PedAM

Pediatric Disease Annotations & Medicines


	clear cell adenocarcinoma

Disease ID	1857
Disease	clear cell adenocarcinoma
Definition	An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)
Synonym	[m]clear cell adenocarcinoma nos [m]clear cell adenocarcinoma nos (morphologic abnormality) adenocarcinoma cell clear adenocarcinoma clear cell adenocarcinoma, clear cell adenocarcinoma, clear cell [disease/finding] adenocarcinoma, clear cell, malignant adenocarcinomas, clear cell carcinoma cell clear carcinoma clear cell carcinomas cell clear clear cell adenocarcinoma (morphologic abnormality) clear cell adenocarcinoma, mesonephroid clear cell adenocarcinoma, nos clear cell adenocarcinomas clear cell carcinoma malignant glandular clear cell mesonephroid clear cell adenocarcinoma mesonephroid clear cell carcinoma
DOID	DOID:4468
UMLS	C0206681
MeSH	D018262
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:11) C0014175 \| endometriosis \| 5 C0152443 \| urethral diverticulum \| 2 C0156347 \| intestinal endometriosis \| 1 C1140680 \| ovarian cancer \| 1 C0677886 \| epithelial ovarian cancer \| 1 C0001418 \| adenocarcinoma \| 1 C1140680 \| ovarian ca \| 1 C1140680 \| ovarian cancers \| 1 C0153687 \| skin metastases \| 1 C0007138 \| urothelial carcinoma \| 1 C0206681 \| clear cell carcinoma \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) TP53 \| 7157 \| CTD_human BCL2 \| 596 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:104) 3675 \| ITGA3 \| DISEASES 6515 \| SLC2A3 \| DISEASES 3861 \| KRT14 \| DISEASES 54474 \| KRT20 \| DISEASES 2099 \| ESR1 \| DISEASES 113791 \| PIK3IP1 \| DISEASES 23492 \| CBX7 \| DISEASES 7380 \| UPK3A \| DISEASES 27294 \| DHDH \| DISEASES 1048 \| CEACAM5 \| DISEASES 10061 \| ABCF2 \| DISEASES 7980 \| TFPI2 \| DISEASES 6928 \| HNF1B \| DISEASES 2026 \| ENO2 \| DISEASES 4292 \| MLH1 \| DISEASES 9479 \| MAPK8IP1 \| DISEASES 51426 \| POLK \| DISEASES 8220 \| DGCR14 \| DISEASES 3852 \| KRT5 \| DISEASES 81 \| ACTN4 \| DISEASES 9476 \| NAPSA \| DISEASES 29923 \| HILPDA \| DISEASES 10643 \| IGF2BP3 \| DISEASES 5460 \| POU5F1 \| DISEASES 84692 \| CCDC54 \| DISEASES 8140 \| SLC7A5 \| DISEASES 6855 \| SYP \| DISEASES 28960 \| DCPS \| DISEASES 5290 \| PIK3CA \| DISEASES 867 \| CBL \| DISEASES 306 \| ANXA3 \| DISEASES 1462 \| VCAN \| DISEASES 29999 \| FSCN3 \| DISEASES 4240 \| MFGE8 \| DISEASES 7157 \| TP53 \| DISEASES 2064 \| ERBB2 \| DISEASES 3858 \| KRT10 \| DISEASES 10769 \| PLK2 \| DISEASES 54361 \| WNT4 \| DISEASES 3856 \| KRT8 \| DISEASES 10825 \| NEU3 \| DISEASES 1381 \| CRABP1 \| DISEASES 2990 \| GUSB \| DISEASES 1540 \| CYLD \| DISEASES 947 \| CD34 \| DISEASES 3642 \| INSM1 \| DISEASES 354 \| KLK3 \| DISEASES 4233 \| MET \| DISEASES 4684 \| NCAM1 \| DISEASES 129807 \| NEU4 \| DISEASES 8289 \| ARID1A \| DISEASES 84260 \| TCHP \| DISEASES 5241 \| PGR \| DISEASES 7481 \| WNT11 \| DISEASES 3855 \| KRT7 \| DISEASES 5463 \| POU6F1 \| DISEASES 7490 \| WT1 \| DISEASES 1287 \| COL4A5 \| DISEASES 4088 \| SMAD3 \| DISEASES 196528 \| ARID2 \| DISEASES 3091 \| HIF1A \| DISEASES 64778 \| FNDC3B \| DISEASES 23583 \| SMUG1 \| DISEASES 2810 \| SFN \| DISEASES 10164 \| CHST4 \| DISEASES 4089 \| SMAD4 \| DISEASES 5154 \| PDGFA \| DISEASES 7080 \| NKX2-1 \| DISEASES 5294 \| PIK3CG \| DISEASES 4311 \| MME \| DISEASES 3880 \| KRT19 \| DISEASES 722 \| C4BPA \| DISEASES 4582 \| MUC1 \| DISEASES 6277 \| S100A6 \| DISEASES 85413 \| SLC22A16 \| DISEASES 3897 \| L1CAM \| DISEASES 23566 \| LPAR3 \| DISEASES 7422 \| VEGFA \| DISEASES 2017 \| CTTN \| DISEASES 768 \| CA9 \| DISEASES 1645 \| AKR1C1 \| DISEASES 1045 \| CDX2 \| DISEASES 23600 \| AMACR \| DISEASES 6624 \| FSCN1 \| DISEASES 2878 \| GPX3 \| DISEASES 3875 \| KRT18 \| DISEASES 174 \| AFP \| DISEASES 5744 \| PTHLH \| DISEASES 144195 \| SLC2A14 \| DISEASES 1781 \| DYNC1I2 \| DISEASES 344022 \| NOTO \| DISEASES 23243 \| ANKRD28 \| DISEASES 1029 \| CDKN2A \| DISEASES 7849 \| PAX8 \| DISEASES 5076 \| PAX2 \| DISEASES 4588 \| MUC6 \| DISEASES 4583 \| MUC2 \| DISEASES 6513 \| SLC2A1 \| DISEASES 4586 \| MUC5AC \| DISEASES 55733 \| HHAT \| DISEASES 6510 \| SLC1A5 \| DISEASES 246734 \| NPCDR1 \| DISEASES 100038246 \| TLX1NB \| DISEASES 51352 \| WT1-AS \| DISEASES
Locus	(Waiting for update.)

Disease ID	1857
Disease	clear cell adenocarcinoma
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:6) HP:0030127 \| Endometriosis \| 5 HP:0008722 \| Urethral diverticulum \| 2 HP:0000079 \| Urinary tract anomalies \| 1 HP:0030731 \| Carcinoma \| 1 HP:0000078 \| Genital abnormalities \| 1 HP:0002664 \| Neoplasia \| 1

Disease ID	1857
Disease	clear cell adenocarcinoma
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0206681	diethylstilbestrol	D004054	56-53-1	adenocarcinoma, clear cell	MESH:D018262	marker/mechanism	11437935

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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