PedAM

Pediatric Disease Annotations & Medicines


	chronic lymphocytic leukemia

Disease ID	251
Disease	chronic lymphocytic leukemia
Definition	chronic leukemia characterized by morphologically mature but immunologically less mature lymphocytes; manifested by an abnormal accumulation of these cells in blood, bone marrow, and lymphatic tissue.
Synonym	[m]chronic lymphoid leukaemia [m]chronic lymphoid leukaemia (disorder) [m]chronic lymphoid leukemia b cell chronic lymphocytic leukemia b cell cll b cell leukemia b cell leukemia, chronic b cell lymphocytic leukemia b chronic lymphocytic leukemia b lymphocytic leukemia, chronic b-cell chronic lymphocytic leukaemia b-cell chronic lymphocytic leukaemia/small lymphocytic lymphoma b-cell chronic lymphocytic leukemia b-cell chronic lymphocytic leukemia (disorder) b-cell chronic lymphocytic leukemia/small lymphocytic lymphoma b-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (morphologic abnormality) b-cell chronic lymphogenous leukemia b-cell chronic lymphoid leukemia b-cell cll b-cell leukemia b-cell leukemia, chronic b-cell leukemias, chronic b-cell lymphocytic leukemia b-cell malignancy, low-grade b-cll - b-cell chronic lymphocytic leukaemia b-cll - b-cell chronic lymphocytic leukemia b-lymphocytic leukemia, chronic b-lymphocytic leukemias, chronic bcll chronic b-cell leukemia chronic b-cell leukemias chronic b-cell lymphocytic leukemia chronic b-lymphocytic leukemia chronic b-lymphocytic leukemias chronic leukemia lymphocytic chronic lymphatic leukaemia chronic lymphatic leukemia chronic lymphoblastic leukemia chronic lymphoblastic leukemias chronic lymphocytic leukaemia chronic lymphocytic leukaemia, b-cell type chronic lymphocytic leukemia (cll) chronic lymphocytic leukemia, b-cell chronic lymphocytic leukemia, b-cell type chronic lymphocytic leukemia, morphology (morphologic abnormality) chronic lymphocytic leukemia, nos chronic lymphocytic leukemias chronic lymphogenous leukemia chronic lymphoid leukaemia chronic lymphoid leukaemia, disease chronic lymphoid leukemia chronic lymphoid leukemia, disease chronic lymphoid leukemia, disease (disorder) cll cll - chronic lymphocytic leukaemia cll - chronic lymphocytic leukemia cll chronic lymphocytic leukemia cll lymphoplasmacytoid lymphoma cll lymphoplasmacytoid lymphomas cll, b-cell clls diffuse well differ lymphocytic lymphoma diffuse well differentiated lymphocytic lymphoma diffuse well-differentiated lymphocytic lymphoma disrupted in b-cell malignancy hematopoeitic - chronic lymphocytic leukemia (cll) leukemia b cell leukemia chronic lymphocytic leukemia lymphocytic chronic leukemia, b cell, chronic leukemia, b-cell chronic lymphocytic leukemia, b-cell, chronic leukemia, chronic b-cell leukemia, chronic b-lymphocytic leukemia, chronic lymphatic leukemia, chronic lymphocytic leukemia, chronic lymphocytic (cll) leukemia, chronic lymphocytic, b-cell leukemia, lymphoblastic, chronic leukemia, lymphocytic, chronic leukemia, lymphocytic, chronic, b cell leukemia, lymphocytic, chronic, b-cell leukemia, lymphocytic, chronic, b-cell [disease/finding] leukemias, chronic b-cell leukemias, chronic b-lymphocytic leukemias, chronic lymphoblastic lymphoblastic leukemia, chronic lymphoblastic leukemias, chronic lymphocytic leukemia chronic lymphocytic leukemia chronic b lymphocytic leukemia, b-cell chronic lymphocytic leukemia, chronic lymphocytic leukemia, chronic, b cell lymphocytic leukemia, chronic, b-cell lymphocytic leukemias, chronic lymphocytic lymphoma lymphocytic lymphoma diffuse well differ lymphocytic lymphoma well differ lymphocytic lymphoma, diffuse, well differentiated lymphocytic lymphoma, diffuse, well-differentiated lymphocytic lymphoma, small lymphocytic lymphoma, well differentiated lymphocytic lymphoma, well-differentiated lymphocytic lymphomas lymphocytic lymphomas, small lymphocytic lymphomas, well-differentiated lymphoid leukemia, chronic lymphoma lymphocytic diffuse well differ lymphoma lymphocytic well differ lymphoma small lymphoma, cll lymphoplasmacytoid lymphoma, lymphocytic lymphoma, lymphocytic, diffuse, well differentiated lymphoma, lymphocytic, diffuse, well-differentiated lymphoma, lymphocytic, well differentiated lymphoma, lymphocytic, well-differentiated lymphoma, lymphoplasmacytoid, cll lymphoma, small cell lymphoma, small lymphocytic lymphoma, small lymphocytic, plasmacytoid lymphoma, small-cell lymphoma, well-differentiated lymphocytic lymphomas, cll lymphoplasmacytoid lymphomas, lymphocytic lymphomas, small lymphocytic lymphomas, small-cell lymphomas, well-differentiated lymphocytic lymphoplasmacytoid lymphoma, cll lymphoplasmacytoid lymphomas, cll small cell lymphoma small lymphocytic lymphoma small lymphocytic lymphomas small lymphoma small-cell lymphoma small-cell lymphomas well-differentiated lymphocytic lymphoma well-differentiated lymphocytic lymphomas
Orphanet	ORPHANET:67038
OMIM	OMIM:151400 OMIM:109543
DOID	DOID:1040
UMLS	C0023434
MeSH	D015451
SNOMED-CT	SNOMEDCT_US_2016_09_01:277473004;SNOMEDCT_US_2016_09_01:92814006
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:160) C0024299 \| lymphoma \| 17 C0023418 \| leukemia \| 15 C0002871 \| anemia \| 9 C0002878 \| hemolytic anemia \| 8 C0019158 \| hepatitis \| 7 C0002880 \| autoimmune hemolytic anemia \| 6 C0040034 \| thrombocytopenia \| 6 C0079731 \| b-cell lymphoma \| 4 C0023470 \| myeloid leukemia \| 4 C0349631 \| richter syndrome \| 4 C0272286 \| immune thrombocytopenia \| 4 C0025202 \| melanoma \| 3 C0024302 \| large cell lymphoma \| 3 C0024291 \| hemophagocytic lymphohistiocytosis \| 3 C0040028 \| essential thrombocythemia \| 3 C0035078 \| renal failure \| 3 C0349631 \| richter's transformation \| 3 C0079744 \| diffuse large b-cell lymphoma \| 3 C0019196 \| hepatitis c \| 3 C0023448 \| lymphocytic leukemia \| 3 C0007129 \| merkel cell carcinoma \| 3 C0553723 \| cutaneous squamous cell carcinoma \| 2 C0007137 \| squamous cell carcinoma \| 2 C0023467 \| acute myeloid leukemia \| 2 C0598894 \| monocytic leukemia \| 2 C0023524 \| progressive multifocal leukoencephalopathy \| 2 C0027697 \| nephritis \| 2 C0020437 \| hypercalcemia \| 2 C0023473 \| chronic myeloid leukemia \| 2 C0024205 \| lymphadenitis \| 2 C0027707 \| interstitial nephritis \| 2 C0032285 \| pneumonia \| 2 C0024305 \| non-hodgkin's lymphoma \| 2 C0023443 \| hairy cell leukemia \| 2 C0270612 \| leukoencephalopathy \| 2 C0030807 \| pemphigus \| 2 C0042769 \| viral infections \| 2 C0015230 \| rash \| 2 C0007114 \| skin cancer \| 2 C0042384 \| vasculitis \| 2 C0019829 \| hodgkin's lymphoma \| 2 C0206180 \| anaplastic large cell lymphoma \| 2 C0042769 \| virus infection \| 2 C0836924 \| thrombocythemia \| 2 C0042769 \| viral infection \| 2 C0002726 \| amyloidosis \| 2 C0023434 \| chronic lymphocytic leukemia \| 2 C0022660 \| acute renal failure \| 2 C0001430 \| adenoma \| 1 C0024790 \| paroxysmal nocturnal hemoglobinuria \| 1 C0001125 \| lactic acidosis \| 1 C0026948 \| mycosis fungoides \| 1 C0014541 \| epiglottitis \| 1 C0039446 \| telangiectasia \| 1 C0024299 \| lymphomas \| 1 C0242379 \| lung cancer \| 1 C0012813 \| diverticulitis \| 1 C0302592 \| cervical ca \| 1 C0027051 \| myocardial infarct \| 1 C1302547 \| chronic lymphocytic leukemia/small lymphocytic lymphoma \| 1 C0002871 \| anaemia \| 1 C0025289 \| meningitis \| 1 C0079773 \| cutaneous t-cell lymphoma \| 1 C0600139 \| prostate carcinoma \| 1 C0021053 \| immune dysfunction \| 1 C0023434 \| small lymphocytic lymphoma \| 1 C0007114 \| skin cancers \| 1 C0376358 \| prostate cancer \| 1 C0023465 \| acute monocytic leukemia \| 1 C0334463 \| malignant fibrous histiocytoma \| 1 C0279682 \| bladder adenocarcinoma \| 1 C0025202 \| malignant melanoma \| 1 C0001815 \| myelofibrosis \| 1 C0017665 \| membranous nephropathy \| 1 C0008325 \| cholecystitis \| 1 C0023281 \| leishmaniasis \| 1 C0155626 \| acute myocardial infarction \| 1 C0024899 \| mastocytosis \| 1 C0007102 \| colon cancer \| 1 C0042721 \| hepatitis viral \| 1 C0278678 \| metastatic renal cell carcinoma \| 1 C0017668 \| focal segmental glomerulosclerosis \| 1 C1955861 \| t-lgl leukemia \| 1 C0024198 \| lyme disease \| 1 C0041349 \| tubulointerstitial nephritis \| 1 C0019163 \| hepatitis b \| 1 C0456909 \| blindness \| 1 C0085074 \| granuloma annulare \| 1 C0004030 \| aspergillosis \| 1 C0023493 \| adult t-cell leukemia \| 1 C0079731 \| b cell lymphoma \| 1 C0025309 \| meningoencephalitis \| 1 C0178664 \| glomerulosclerosis \| 1 C0014735 \| erysipelothrix \| 1 C0041296 \| tuberculosis \| 1 C1509147 \| histiocytoma \| 1 C0019048 \| hemoglobinuria \| 1 C0699893 \| non-melanoma skin cancer \| 1 C0026277 \| pleomorphic adenoma \| 1 C0026946 \| mycosis \| 1 C0007134 \| renal cell carcinoma \| 1 C0007847 \| cervical cancer \| 1 C0279651 \| gallbladder adenocarcinoma \| 1 C0004135 \| ataxia telangiectasia \| 1 C1704214 \| xanthogranuloma \| 1 C0281963 \| red cell aplasia \| 1 C0042109 \| urticaria \| 1 C0023492 \| t-cell leukemia \| 1 C0041321 \| miliary tuberculosis \| 1 C0027051 \| myocardial infarction \| 1 C0026764 \| multiple myeloma \| 1 C0014130 \| endocrinopathy \| 1 C0001824 \| agranulocytosis \| 1 C0442874 \| neuropathy \| 1 C0024312 \| lymphopenia \| 1 C0026764 \| myeloma \| 1 C0027022 \| myeloproliferative neoplasms \| 1 C0001418 \| adenocarcinoma \| 1 C0155357 \| posterior scleritis \| 1 C0206644 \| fibrous histiocytoma \| 1 C0162871 \| abdominal aortic aneurysm \| 1 C0221013 \| systemic mastocytosis \| 1 C0085436 \| cryptococcal meningitis \| 1 C0011603 \| dermatitis \| 1 C0024314 \| lymphoproliferative disorder \| 1 C0018202 \| granulomatous vasculitis \| 1 C0024198 \| borrelia burgdorferi infection \| 1 C0030326 \| panniculitis \| 1 C0019204 \| hepatocellular carcinoma \| 1 C0037998 \| splenic infarction \| 1 C0043541 \| zygomycosis \| 1 C0022658 \| nephropathy \| 1 C0011991 \| diarrhea \| 1 C0023486 \| prolymphocytic leukemia \| 1 C0030312 \| pancytopenia \| 1 C0036416 \| scleritis \| 1 C0023798 \| lipomas \| 1 C0029132 \| optic neuropathy \| 1 C0020676 \| hypothyroidism \| 1 C0042721 \| viral hepatitis \| 1 C0376480 \| gingival enlargement \| 1 C0023860 \| listeriosis \| 1 C0003486 \| aortic aneurysm \| 1 C0023470 \| myelogenous leukemia \| 1 C0349631 \| richter's syndrome \| 1 C0034902 \| pure red cell aplasia \| 1 C0023434 \| b-cell leukemia \| 1 C0023290 \| visceral leishmaniasis \| 1 C0030354 \| papilloma \| 1 C0027947 \| neutropenia \| 1 C0026986 \| myelodysplastic syndrome \| 1 C0014038 \| encephalitis \| 1 C0001768 \| agammaglobulinemia \| 1 C0008049 \| varicella \| 1 C0023473 \| chronic myelogenous leukemia \| 1 C0015624 \| fanconi syndrome \| 1 C0023448 \| lymphoblastic leukemia \| 1 C0019829 \| hodgkin lymphoma \| 1 C0206067 \| focal epithelial hyperplasia \| 1 C0024623 \| gastric cancer \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:58) IL6 \| 3569 \| CTD_human HLA-DQA1 \| 3117 \| GWASCAT TP53 \| 7157 \| CTD_human;ORPHANET PMAIP1 \| 5366 \| CTD_human FAS \| 355 \| GWASCAT BCL2 \| 596 \| CTD_human;GWASCAT KLRC4 \| 8302 \| CTD_human CASP8 \| 841 \| GWASCAT C6orf10 \| 10665 \| GWASCAT CCND1 \| 595 \| CTD_human;ORPHANET PTGS2 \| 5743 \| CTD_human IRF4 \| 3662 \| CTD_human;GWASCAT IPCEF1 \| 26034 \| GWASCAT IKZF3 \| 22806 \| ORPHANET TNFRSF11A \| 8792 \| CTD_human ACTA2 \| 59 \| GWASCAT ACOXL \| 55289 \| CTD_human;GWASCAT MTHFR \| 4524 \| CTD_human SP140 \| 11262 \| CTD_human;GWASCAT CAMK2D \| 817 \| GWASCAT LEF1 \| 51176 \| CTD_human;GWASCAT OPRM1 \| 4988 \| GWASCAT CLPTM1L \| 81037 \| GWASCAT ARL11 \| 115761 \| CTD_human;ORPHANET TNFSF11 \| 8600 \| CTD_human RBL2 \| 5934 \| CTD_human BAK1 \| 578 \| GWASCAT TFRC \| 7037 \| CTD_human CDKN2B-AS1 \| 100048912 \| CTD_human VDR \| 7421 \| CTD_human IGHV3-21 \| 28444 \| CTD_human;ORPHANET PRKD2 \| 25865 \| CTD_human;GWASCAT C11orf21 \| 29125 \| CTD_human ATM \| 472 \| CTD_human;ORPHANET CD5 \| 921 \| CTD_human IRF8 \| 3394 \| GWASCAT CPEB1 \| 64506 \| CTD_human GRAMD1B \| 57476 \| GWASCAT FARP2 \| 9855 \| CTD_human;GWASCAT IGHG1 \| 3500 \| ORPHANET TOPBP1 \| 11073 \| CTD_human P2RX7 \| 5027 \| CTD_human;ORPHANET MIR145 \| 406937 \| CTD_human MYNN \| 55892 \| GWASCAT QPCT \| 25797 \| CTD_human MIR16-1 \| 406950 \| CTD_human POLB \| 5423 \| CTD_human SF3B1 \| 23451 \| CTD_human MIR143 \| 406935 \| CTD_human POT1 \| 25913 \| ORPHANET;GWASCAT RPS15 \| 6209 \| ORPHANET BMF \| 90427 \| CTD_human RFX7 \| 64864 \| GWASCAT IL19 \| 29949 \| CTD_human LILRA4 \| 23547 \| CTD_human ITGA4 \| 3676 \| CTD_human PPP2R5C \| 5527 \| CTD_human SP110 \| 3431 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:216) 3586 \| IL10 \| infer 8797 \| TNFRSF10A \| infer 55289 \| ACOXL \| infer 10018 \| BCL2L11 \| infer 64506 \| CPEB1 \| infer 30827 \| CXXC1 \| infer 9855 \| FARP2 \| infer 57476 \| GRAMD1B \| infer 3569 \| IL6 \| infer 3662 \| IRF4 \| infer 3394 \| IRF8 \| infer 4152 \| MBD1 \| infer 4734 \| NEDD4 \| infer 25865 \| PRKD2 \| infer 64864 \| RFX7 \| infer 3431 \| SP110 \| infer 11262 \| SP140 \| infer 29888 \| STRN4 \| infer 581 \| BAX \| infer 3106 \| HLA-B \| infer 3115 \| HLA-DPB1 \| infer 3119 \| HLA-DQB1 \| infer 3123 \| HLA-DRB1 \| infer 5243 \| ABCB1 \| infer 207 \| AKT1 \| infer 238 \| ALK \| infer 317 \| APAF1 \| infer 348 \| APOE \| infer 472 \| ATM \| infer 545 \| ATR \| infer 9212 \| AURKB \| infer 578 \| BAK1 \| infer 596 \| BCL2 \| infer 604 \| BCL6 \| infer 637 \| BID \| infer 332 \| BIRC5 \| infer 84312 \| BRMS1L \| infer 701 \| BUB1B \| infer 824 \| CAPN2 \| infer 825 \| CAPN3 \| infer 10753 \| CAPN9 \| infer 22900 \| CARD8 \| infer 834 \| CASP1 \| infer 843 \| CASP10 \| infer 835 \| CASP2 \| infer 836 \| CASP3 \| infer 838 \| CASP5 \| infer 841 \| CASP8 \| infer 842 \| CASP9 \| infer 6347 \| CCL2 \| infer 10850 \| CCL27 \| infer 595 \| CCND1 \| infer 902 \| CCNH \| infer 1236 \| CCR7 \| infer 1237 \| CCR8 \| infer 940 \| CD28 \| infer 952 \| CD38 \| infer 995 \| CDC25C \| infer 990 \| CDC6 \| infer 1021 \| CDK6 \| infer 1063 \| CENPF \| infer 729530 \| CNOT6LP1 \| infer 1375 \| CPT1B \| infer 1493 \| CTLA4 \| infer 6387 \| CXCL12 \| infer 7852 \| CXCR4 \| infer 643 \| CXCR5 \| infer 1543 \| CYP1A1 \| infer 1545 \| CYP1B1 \| infer 1555 \| CYP2B6 \| infer 1562 \| CYP2C18 \| infer 1557 \| CYP2C19 \| infer 1558 \| CYP2C8 \| infer 1559 \| CYP2C9 \| infer 1571 \| CYP2E1 \| infer 1580 \| CYP4B1 \| infer 64421 \| DCLRE1C \| infer 27185 \| DISC1 \| infer 1870 \| E2F2 \| infer 1906 \| EDN1 \| infer 1950 \| EGF \| infer 1956 \| EGFR \| infer 2026 \| ENO2 \| infer 2052 \| EPHX1 \| infer 2053 \| EPHX2 \| infer 2068 \| ERCC2 \| infer 2072 \| ERCC4 \| infer 2073 \| ERCC5 \| infer 2074 \| ERCC6 \| infer 114799 \| ESCO1 \| infer 157570 \| ESCO2 \| infer 9156 \| EXO1 \| infer 2146 \| EZH2 \| infer 8772 \| FADD \| infer 2249 \| FGF4 \| infer 79147 \| FKRP \| infer 51053 \| GMNN \| infer 2778 \| GNAS \| infer 2939 \| GSTA2 \| infer 2944 \| GSTM1 \| infer 2947 \| GSTM3 \| infer 2950 \| GSTP1 \| infer 2952 \| GSTT1 \| infer 2954 \| GSTZ1 \| infer 3077 \| HFE \| infer 3310 \| HSPA6 \| infer 3383 \| ICAM1 \| infer 29851 \| ICOS \| infer 3458 \| IFNG \| infer 3482 \| IGF2R \| infer 3592 \| IL12A \| infer 3594 \| IL12RB1 \| infer 3596 \| IL13 \| infer 3603 \| IL16 \| infer 3606 \| IL18 \| infer 3552 \| IL1A \| infer 3553 \| IL1B \| infer 9173 \| IL1RL1 \| infer 8808 \| IL1RL2 \| infer 3557 \| IL1RN \| infer 3562 \| IL3 \| infer 3565 \| IL4 \| infer 3566 \| IL4R \| infer 3568 \| IL5RA \| infer 3572 \| IL6ST \| infer 51135 \| IRAK4 \| infer 3675 \| ITGA3 \| infer 3676 \| ITGA4 \| infer 3682 \| ITGAE \| infer 3691 \| ITGB4 \| infer 3981 \| LIG4 \| infer 4049 \| LTA \| infer 4173 \| MCM4 \| infer 4174 \| MCM5 \| infer 9656 \| MDC1 \| infer 4193 \| MDM2 \| infer 4323 \| MMP14 \| infer 4317 \| MMP8 \| infer 4318 \| MMP9 \| infer 4436 \| MSH2 \| infer 4524 \| MTHFR \| infer 4552 \| MTRR \| infer 9683 \| N4BP1 \| infer 9 \| NAT1 \| infer 10 \| NAT2 \| infer 4683 \| NBN \| infer 22861 \| NLRP1 \| infer 204801 \| NLRP11 \| infer 126204 \| NLRP13 \| infer 338323 \| NLRP14 \| infer 55655 \| NLRP2 \| infer 147945 \| NLRP4 \| infer 126206 \| NLRP5 \| infer 126205 \| NLRP8 \| infer 10392 \| NOD1 \| infer 64127 \| NOD2 \| infer 4843 \| NOS2 \| infer 1728 \| NQO1 \| infer 4986 \| OPRK1 \| infer 4988 \| OPRM1 \| infer 5027 \| P2RX7 \| infer 5028 \| P2RY1 \| infer 142 \| PARP1 \| infer 5156 \| PDGFRA \| infer 5159 \| PDGFRB \| infer 5371 \| PML \| infer 5426 \| POLE \| infer 11201 \| POLI \| infer 27343 \| POLL \| infer 5529 \| PPP2R5E \| infer 5591 \| PRKDC \| infer 5727 \| PTCH1 \| infer 5810 \| RAD1 \| infer 5885 \| RAD21 \| infer 5887 \| RAD23B \| infer 5888 \| RAD51 \| infer 5896 \| RAG1 \| infer 5909 \| RAP1GAP \| infer 5934 \| RBL2 \| infer 1827 \| RCAN1 \| infer 11123 \| RCAN3 \| infer 51455 \| REV1 \| infer 5980 \| REV3L \| infer 6176 \| RPLP1 \| infer 6402 \| SELL \| infer 6403 \| SELP \| infer 6404 \| SELPLG \| infer 9154 \| SLC28A1 \| infer 9153 \| SLC28A2 \| infer 64078 \| SLC28A3 \| infer 4092 \| SMAD7 \| infer 6648 \| SOD2 \| infer 401475 \| SRRM1P1 \| infer 7124 \| TNF \| infer 8795 \| TNFRSF10B \| infer 8792 \| TNFRSF11A \| infer 23495 \| TNFRSF13B \| infer 115650 \| TNFRSF13C \| infer 7133 \| TNFRSF1B \| infer 8741 \| TNFSF13 \| infer 10673 \| TNFSF13B \| infer 7153 \| TOP2A \| infer 7157 \| TP53 \| infer 7158 \| TP53BP1 \| infer 7161 \| TP73 \| infer 7187 \| TRAF3 \| infer 7412 \| VCAM1 \| infer 7422 \| VEGFA \| infer 6375 \| XCL1 \| infer 7508 \| XPC \| infer 7515 \| XRCC1 \| infer 7516 \| XRCC2 \| infer 7518 \| XRCC4 \| infer 7520 \| XRCC5 \| infer 2547 \| XRCC6 \| infer 100131879 \| ZYG11AP1 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:638) 10301 \| DLEU1 \| DISEASES 8847 \| DLEU2 \| DISEASES 2519 \| FUCA2 \| DISEASES 55365 \| TMEM176A \| DISEASES 1856 \| DVL2 \| DISEASES 4706 \| NDUFAB1 \| DISEASES 3675 \| ITGA3 \| DISEASES 1407 \| CRY1 \| DISEASES 928 \| CD9 \| DISEASES 972 \| CD74 \| DISEASES 3937 \| LCP2 \| DISEASES 608 \| TNFRSF17 \| DISEASES 933 \| CD22 \| DISEASES 3385 \| ICAM3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 602 \| BCL3 \| DISEASES 10272 \| FSTL3 \| DISEASES 3566 \| IL4R \| DISEASES 30009 \| TBX21 \| DISEASES 51291 \| GMIP \| DISEASES 3902 \| LAG3 \| DISEASES 7066 \| THPO \| DISEASES 9274 \| BCL7C \| DISEASES 4616 \| GADD45B \| DISEASES 5594 \| MAPK1 \| DISEASES 79019 \| CENPM \| DISEASES 7494 \| XBP1 \| DISEASES 6767 \| ST13 \| DISEASES 3560 \| IL2RB \| DISEASES 83933 \| HDAC10 \| DISEASES 3002 \| GZMB \| DISEASES 4792 \| NFKBIA \| DISEASES 79444 \| BIRC7 \| DISEASES 54 \| ACP5 \| DISEASES 55824 \| PAG1 \| DISEASES 9694 \| EMC2 \| DISEASES 8797 \| TNFRSF10A \| DISEASES 5971 \| RELB \| DISEASES 10535 \| RNASEH2A \| DISEASES 973 \| CD79A \| DISEASES 5296 \| PIK3R2 \| DISEASES 51384 \| WNT16 \| DISEASES 944 \| TNFSF8 \| DISEASES 29760 \| BLNK \| DISEASES 6348 \| CCL3 \| DISEASES 1440 \| CSF3 \| DISEASES 7473 \| WNT3 \| DISEASES 51225 \| ABI3 \| DISEASES 952 \| CD38 \| DISEASES 4790 \| NFKB1 \| DISEASES 3558 \| IL2 \| DISEASES 6688 \| SPI1 \| DISEASES 595 \| CCND1 \| DISEASES 329 \| BIRC2 \| DISEASES 969 \| CD69 \| DISEASES 1027 \| CDKN1B \| DISEASES 3458 \| IFNG \| DISEASES 56994 \| CHPT1 \| DISEASES 57379 \| AICDA \| DISEASES 3593 \| IL12B \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 9631 \| NUP155 \| DISEASES 604 \| BCL6 \| DISEASES 5341 \| PLEK \| DISEASES 11126 \| CD160 \| DISEASES 6402 \| SELL \| DISEASES 7128 \| TNFAIP3 \| DISEASES 1843 \| DUSP1 \| DISEASES 7976 \| FZD3 \| DISEASES 22914 \| KLRK1 \| DISEASES 8743 \| TNFSF10 \| DISEASES 2322 \| FLT3 \| DISEASES 27434 \| POLM \| DISEASES 1959 \| EGR2 \| DISEASES 5153 \| PDE1B \| DISEASES 1026 \| CDKN1A \| DISEASES 970 \| CD70 \| DISEASES 718 \| C3 \| DISEASES 1340 \| COX6B1 \| DISEASES 1236 \| CCR7 \| DISEASES 83596 \| BCL2L12 \| DISEASES 83460 \| EMC6 \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 599 \| BCL2L2 \| DISEASES 2056 \| EPO \| DISEASES 10155 \| TRIM28 \| DISEASES 8572 \| PDLIM4 \| DISEASES 6382 \| SDC1 \| DISEASES 3975 \| LHX1 \| DISEASES 84674 \| CARD6 \| DISEASES 7014 \| TERF2 \| DISEASES 1022 \| CDK7 \| DISEASES 4064 \| CD180 \| DISEASES 10752 \| CHL1 \| DISEASES 4853 \| NOTCH2 \| DISEASES 301 \| ANXA1 \| DISEASES 4907 \| NT5E \| DISEASES 1019 \| CDK4 \| DISEASES 55619 \| DOCK10 \| DISEASES 55213 \| RCBTB1 \| DISEASES 3569 \| IL6 \| DISEASES 6366 \| CCL21 \| DISEASES 971 \| CD72 \| DISEASES 8335 \| HIST1H2AB \| DISEASES 57569 \| ARHGAP20 \| DISEASES 10017 \| BCL2L10 \| DISEASES 10113 \| PREB \| DISEASES 84692 \| CCDC54 \| DISEASES 894 \| CCND2 \| DISEASES 51646 \| YPEL5 \| DISEASES 55728 \| N4BP2 \| DISEASES 7188 \| TRAF5 \| DISEASES 23495 \| TNFRSF13B \| DISEASES 23197 \| FAF2 \| DISEASES 9172 \| MYOM2 \| DISEASES 945 \| CD33 \| DISEASES 4591 \| TRIM37 \| DISEASES 23239 \| PHLPP1 \| DISEASES 25939 \| SAMHD1 \| DISEASES 7515 \| XRCC1 \| DISEASES 5595 \| MAPK3 \| DISEASES 5264 \| PHYH \| DISEASES 3682 \| ITGAE \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 330 \| BIRC3 \| DISEASES 975 \| CD81 \| DISEASES 3574 \| IL7 \| DISEASES 55850 \| USE1 \| DISEASES 3791 \| KDR \| DISEASES 943 \| TNFRSF8 \| DISEASES 9855 \| FARP2 \| DISEASES 2208 \| FCER2 \| DISEASES 1716 \| DGUOK \| DISEASES 941 \| CD80 \| DISEASES 59067 \| IL21 \| DISEASES 2247 \| FGF2 \| DISEASES 7474 \| WNT5A \| DISEASES 6774 \| STAT3 \| DISEASES 1788 \| DNMT3A \| DISEASES 3383 \| ICAM1 \| DISEASES 7535 \| ZAP70 \| DISEASES 683 \| BST1 \| DISEASES 51176 \| LEF1 \| DISEASES 22797 \| TFEC \| DISEASES 5244 \| ABCB4 \| DISEASES 5243 \| ABCB1 \| DISEASES 3263 \| HPX \| DISEASES 51279 \| C1RL \| DISEASES 939 \| CD27 \| DISEASES 1017 \| CDK2 \| DISEASES 3695 \| ITGB7 \| DISEASES 26277 \| TINF2 \| DISEASES 145482 \| PTGR2 \| DISEASES 51234 \| EMC4 \| DISEASES 597 \| BCL2A1 \| DISEASES 3687 \| ITGAX \| DISEASES 1039 \| CDR2 \| DISEASES 124912 \| SPACA3 \| DISEASES 7157 \| TP53 \| DISEASES 207 \| AKT1 \| DISEASES 5141 \| PDE4A \| DISEASES 8915 \| BCL10 \| DISEASES 2212 \| FCGR2A \| DISEASES 83417 \| FCRL4 \| DISEASES 7483 \| WNT9A \| DISEASES 10130 \| PDIA6 \| DISEASES 805 \| CALM2 \| DISEASES 64651 \| CSRNP1 \| DISEASES 4794 \| NFKBIE \| DISEASES 8795 \| TNFRSF10B \| DISEASES 7013 \| TERF1 \| DISEASES 3439 \| IFNA1 \| DISEASES 4851 \| NOTCH1 \| DISEASES 710 \| SERPING1 \| DISEASES 472 \| ATM \| DISEASES 60496 \| AASDHPPT \| DISEASES 85449 \| KIAA1755 \| DISEASES 83706 \| FERMT3 \| DISEASES 823 \| CAPN1 \| DISEASES 5805 \| PTS \| DISEASES 4613 \| MYCN \| DISEASES 5800 \| PTPRO \| DISEASES 55294 \| FBXW7 \| DISEASES 115761 \| ARL11 \| DISEASES 5140 \| PDE3B \| DISEASES 2321 \| FLT1 \| DISEASES 925 \| CD8A \| DISEASES 124540 \| MSI2 \| DISEASES 83539 \| CHST9 \| DISEASES 7345 \| UCHL1 \| DISEASES 1436 \| CSF1R \| DISEASES 1633 \| DCK \| DISEASES 27163 \| NAAA \| DISEASES 10563 \| CXCL13 \| DISEASES 3815 \| KIT \| DISEASES 673 \| BRAF \| DISEASES 55114 \| ARHGAP17 \| DISEASES 3460 \| IFNGR2 \| DISEASES 115650 \| TNFRSF13C \| DISEASES 808 \| CALM3 \| DISEASES 7307 \| U2AF1 \| DISEASES 89858 \| SIGLEC12 \| DISEASES 23547 \| LILRA4 \| DISEASES 9437 \| NCR1 \| DISEASES 63934 \| ZNF667 \| DISEASES 643 \| CXCR5 \| DISEASES 114757 \| CYGB \| DISEASES 6777 \| STAT5B \| DISEASES 3071 \| NCKAP1L \| DISEASES 3678 \| ITGA5 \| DISEASES 255877 \| BCL6B \| DISEASES 7412 \| VCAM1 \| DISEASES 2215 \| FCGR3B \| DISEASES 5966 \| REL \| DISEASES 213 \| ALB \| DISEASES 5500 \| PPP1CB \| DISEASES 1230 \| CCR1 \| DISEASES 5364 \| PLXNB1 \| DISEASES 308 \| ANXA5 \| DISEASES 3600 \| IL15 \| DISEASES 134147 \| CMBL \| DISEASES 9607 \| CARTPT \| DISEASES 10412 \| NSA2 \| DISEASES 3562 \| IL3 \| DISEASES 1437 \| CSF2 \| DISEASES 79698 \| ZMAT4 \| DISEASES 10206 \| TRIM13 \| DISEASES 1200 \| TPP1 \| DISEASES 8800 \| PEX11A \| DISEASES 290 \| ANPEP \| DISEASES 6778 \| STAT6 \| DISEASES 2793 \| GNGT2 \| DISEASES 84669 \| USP32 \| DISEASES 558 \| AXL \| DISEASES 353514 \| LILRA5 \| DISEASES 7083 \| TK1 \| DISEASES 8772 \| FADD \| DISEASES 9081 \| PRY \| DISEASES 5604 \| MAP2K1 \| DISEASES 598 \| BCL2L1 \| DISEASES 8233 \| ZRSR2 \| DISEASES 10648 \| SCGB1D1 \| DISEASES 442862 \| PRY2 \| DISEASES 3688 \| ITGB1 \| DISEASES 613 \| BCR \| DISEASES 442866 \| PRYP4 \| DISEASES 51237 \| MZB1 \| DISEASES 1493 \| CTLA4 \| DISEASES 8403 \| SOX14 \| DISEASES 1901 \| S1PR1 \| DISEASES 25998 \| IBTK \| DISEASES 84522 \| JAGN1 \| DISEASES 3575 \| IL7R \| DISEASES 6504 \| SLAMF1 \| DISEASES 2353 \| FOS \| DISEASES 3708 \| ITPR1 \| DISEASES 2119 \| ETV5 \| DISEASES 9451 \| EIF2AK3 \| DISEASES 54205 \| CYCS \| DISEASES 27087 \| B3GAT1 \| DISEASES 1938 \| EEF2 \| DISEASES 695 \| BTK \| DISEASES 4046 \| LSP1 \| DISEASES 6363 \| CCL19 \| DISEASES 81029 \| WNT5B \| DISEASES 1540 \| CYLD \| DISEASES 7015 \| TERT \| DISEASES 4023 \| LPL \| DISEASES 3265 \| HRAS \| DISEASES 29127 \| RACGAP1 \| DISEASES 947 \| CD34 \| DISEASES 9743 \| ARHGAP32 \| DISEASES 27115 \| PDE7B \| DISEASES 836 \| CASP3 \| DISEASES 131450 \| CD200R1 \| DISEASES 64393 \| ZMAT3 \| DISEASES 924 \| CD7 \| DISEASES 8832 \| CD84 \| DISEASES 8837 \| CFLAR \| DISEASES 5591 \| PRKDC \| DISEASES 4179 \| CD46 \| DISEASES 56895 \| AGPAT4 \| DISEASES 9448 \| MAP4K4 \| DISEASES 2629 \| GBA \| DISEASES 931 \| MS4A1 \| DISEASES 285 \| ANGPT2 \| DISEASES 26031 \| OSBPL3 \| DISEASES 63917 \| GALNT11 \| DISEASES 1604 \| CD55 \| DISEASES 10464 \| PIBF1 \| DISEASES 4684 \| NCAM1 \| DISEASES 27086 \| FOXP1 \| DISEASES 10892 \| MALT1 \| DISEASES 80381 \| CD276 \| DISEASES 2146 \| EZH2 \| DISEASES 3059 \| HCLS1 \| DISEASES 57705 \| WDFY4 \| DISEASES 8334 \| HIST1H2AC \| DISEASES 3039 \| HBA1 \| DISEASES 6664 \| SOX11 \| DISEASES 9203 \| ZMYM3 \| DISEASES 1879 \| EBF1 \| DISEASES 55 \| ACPP \| DISEASES 923 \| CD6 \| DISEASES 5571 \| PRKAG1 \| DISEASES 283518 \| KCNRG \| DISEASES 8227 \| AKAP17A \| DISEASES 940 \| CD28 \| DISEASES 154141 \| MBOAT1 \| DISEASES 951 \| CD37 \| DISEASES 5366 \| PMAIP1 \| DISEASES 152573 \| SHISA3 \| DISEASES 83852 \| SETDB2 \| DISEASES 8204 \| NRIP1 \| DISEASES 4843 \| NOS2 \| DISEASES 1435 \| CSF1 \| DISEASES 23467 \| NPTXR \| DISEASES 4772 \| NFATC1 \| DISEASES 3563 \| IL3RA \| DISEASES 3714 \| JAG2 \| DISEASES 8784 \| TNFRSF18 \| DISEASES 752 \| FMNL1 \| DISEASES 1850 \| DUSP8 \| DISEASES 596 \| BCL2 \| DISEASES 842 \| CASP9 \| DISEASES 79680 \| C22orf29 \| DISEASES 926 \| CD8B \| DISEASES 10320 \| IKZF1 \| DISEASES 942 \| CD86 \| DISEASES 5142 \| PDE4B \| DISEASES 3916 \| LAMP1 \| DISEASES 10742 \| RAI2 \| DISEASES 59307 \| SIGIRR \| DISEASES 2124 \| EVI2B \| DISEASES 151888 \| BTLA \| DISEASES 199786 \| FAM129C \| DISEASES 5133 \| PDCD1 \| DISEASES 3320 \| HSP90AA1 \| DISEASES 23451 \| SF3B1 \| DISEASES 112744 \| IL17F \| DISEASES 3932 \| LCK \| DISEASES 1981 \| EIF4G1 \| DISEASES 92140 \| MTDH \| DISEASES 6622 \| SNCA \| DISEASES 23583 \| SMUG1 \| DISEASES 53335 \| BCL11A \| DISEASES 3572 \| IL6ST \| DISEASES 22978 \| NT5C2 \| DISEASES 3006 \| HIST1H1C \| DISEASES 340120 \| ANKRD34B \| DISEASES 29102 \| DROSHA \| DISEASES 4602 \| MYB \| DISEASES 79469 \| DLEU2L \| DISEASES 966 \| CD59 \| DISEASES 6932 \| TCF7 \| DISEASES 1758 \| DMP1 \| DISEASES 6776 \| STAT5A \| DISEASES 89857 \| KLHL6 \| DISEASES 22837 \| COBLL1 \| DISEASES 259197 \| NCR3 \| DISEASES 442865 \| PRYP3 \| DISEASES 921 \| CD5 \| DISEASES 3716 \| JAK1 \| DISEASES 9623 \| TCL1B \| DISEASES 55975 \| KLHL7 \| DISEASES 545 \| ATR \| DISEASES 53827 \| FXYD5 \| DISEASES 1499 \| CTNNB1 \| DISEASES 22806 \| IKZF3 \| DISEASES 56940 \| DUSP22 \| DISEASES 3767 \| KCNJ11 \| DISEASES 8326 \| FZD9 \| DISEASES 94134 \| ARHGAP12 \| DISEASES 9879 \| DDX46 \| DISEASES 79711 \| IPO4 \| DISEASES 9967 \| THRAP3 \| DISEASES 90427 \| BMF \| DISEASES 2335 \| FN1 \| DISEASES 2331 \| FMOD \| DISEASES 954 \| ENTPD2 \| DISEASES 84936 \| ZFYVE19 \| DISEASES 8871 \| SYNJ2 \| DISEASES 331 \| XIAP \| DISEASES 51287 \| COA4 \| DISEASES 8764 \| TNFRSF14 \| DISEASES 355 \| FAS \| DISEASES 9260 \| PDLIM7 \| DISEASES 54766 \| BTG4 \| DISEASES 10507 \| SEMA4D \| DISEASES 3683 \| ITGAL \| DISEASES 801 \| CALM1 \| DISEASES 10219 \| KLRG1 \| DISEASES 64919 \| BCL11B \| DISEASES 60 \| ACTB \| DISEASES 3177 \| SLC29A2 \| DISEASES 25913 \| POT1 \| DISEASES 1612 \| DAPK1 \| DISEASES 5079 \| PAX5 \| DISEASES 6714 \| SRC \| DISEASES 51592 \| TRIM33 \| DISEASES 841 \| CASP8 \| DISEASES 84986 \| ARHGAP19 \| DISEASES 2213 \| FCGR2B \| DISEASES 2526 \| FUT4 \| DISEASES 5294 \| PIK3CG \| DISEASES 11086 \| ADAM29 \| DISEASES 2547 \| XRCC6 \| DISEASES 5336 \| PLCG2 \| DISEASES 6427 \| SRSF2 \| DISEASES 7037 \| TFRC \| DISEASES 6693 \| SPN \| DISEASES 3135 \| HLA-G \| DISEASES 5599 \| MAPK8 \| DISEASES 140883 \| ZNF280B \| DISEASES 4311 \| MME \| DISEASES 54106 \| TLR9 \| DISEASES 6772 \| STAT1 \| DISEASES 22876 \| INPP5F \| DISEASES 4860 \| PNP \| DISEASES 2475 \| MTOR \| DISEASES 83416 \| FCRL5 \| DISEASES 57213 \| SPRYD7 \| DISEASES 919 \| CD247 \| DISEASES 4283 \| CXCL9 \| DISEASES 4515 \| MTCP1 \| DISEASES 79368 \| FCRL2 \| DISEASES 23038 \| WDTC1 \| DISEASES 961 \| CD47 \| DISEASES 142 \| PARP1 \| DISEASES 6580 \| SLC22A1 \| DISEASES 1378 \| CR1 \| DISEASES 1380 \| CR2 \| DISEASES 4194 \| MDM4 \| DISEASES 26034 \| IPCEF1 \| DISEASES 80328 \| ULBP2 \| DISEASES 5788 \| PTPRC \| DISEASES 356 \| FASLG \| DISEASES 6846 \| XCL2 \| DISEASES 55811 \| ADCY10 \| DISEASES 84824 \| FCRLA \| DISEASES 2214 \| FCGR3A \| DISEASES 51744 \| CD244 \| DISEASES 962 \| CD48 \| DISEASES 343413 \| FCRL6 \| DISEASES 4332 \| MNDA \| DISEASES 912 \| CD1D \| DISEASES 115350 \| FCRL1 \| DISEASES 115352 \| FCRL3 \| DISEASES 6016 \| RIT1 \| DISEASES 3570 \| IL6R \| DISEASES 27287 \| VENTX \| DISEASES 4082 \| MARCKS \| DISEASES 4288 \| MKI67 \| DISEASES 4942 \| OAT \| DISEASES 4170 \| MCL1 \| DISEASES 639 \| PRDM1 \| DISEASES 2209 \| FCGR1A \| DISEASES 914 \| CD2 \| DISEASES 965 \| CD58 \| DISEASES 1847 \| DUSP5 \| DISEASES 84108 \| PCGF6 \| DISEASES 4791 \| NFKB2 \| DISEASES 51611 \| DPH5 \| DISEASES 1038 \| CDR1 \| DISEASES 959 \| CD40LG \| DISEASES 1647 \| GADD45A \| DISEASES 4919 \| ROR1 \| DISEASES 27022 \| FOXD3 \| DISEASES 1791 \| DNTT \| DISEASES 953 \| ENTPD1 \| DISEASES 3725 \| JUN \| DISEASES 29952 \| DPP7 \| DISEASES 2030 \| SLC29A1 \| DISEASES 5728 \| PTEN \| DISEASES 7422 \| VEGFA \| DISEASES 958 \| CD40 \| DISEASES 4318 \| MMP9 \| DISEASES 25 \| ABL1 \| DISEASES 100 \| ADA \| DISEASES 896 \| CCND3 \| DISEASES 4675 \| NAP1L3 \| DISEASES 9436 \| NCR2 \| DISEASES 1025 \| CDK9 \| DISEASES 254065 \| BRWD3 \| DISEASES 65108 \| MARCKSL1 \| DISEASES 2833 \| CXCR3 \| DISEASES 1104 \| RCC1 \| DISEASES 7185 \| TRAF1 \| DISEASES 6118 \| RPA2 \| DISEASES 2268 \| FGR \| DISEASES 9968 \| MED12 \| DISEASES 3561 \| IL2RG \| DISEASES 1043 \| CD52 \| DISEASES 3710 \| ITPR3 \| DISEASES 2517 \| FUCA1 \| DISEASES 7295 \| TXN \| DISEASES 54534 \| MRPL50 \| DISEASES 978 \| CDA \| DISEASES 3014 \| H2AFX \| DISEASES 6850 \| SYK \| DISEASES 10673 \| TNFSF13B \| DISEASES 7917 \| BAG6 \| DISEASES 50943 \| FOXP3 \| DISEASES 64078 \| SLC28A3 \| DISEASES 11040 \| PIM2 \| DISEASES 3105 \| HLA-A \| DISEASES 201176 \| ARHGAP27 \| DISEASES 114798 \| SLITRK1 \| DISEASES 221079 \| ARL5B \| DISEASES 5293 \| PIK3CD \| DISEASES 3604 \| TNFRSF9 \| DISEASES 6520 \| SLC3A2 \| DISEASES 4609 \| MYC \| DISEASES 93035 \| PKHD1L1 \| DISEASES 574028 \| CLLU1 \| DISEASES 5422 \| POLA1 \| DISEASES 9308 \| CD83 \| DISEASES 3559 \| IL2RA \| DISEASES 54790 \| TET2 \| DISEASES 675 \| BRCA2 \| DISEASES 3440 \| IFNA2 \| DISEASES 3446 \| IFNA10 \| DISEASES 3456 \| IFNB1 \| DISEASES 833 \| CARS \| DISEASES 51284 \| TLR7 \| DISEASES 6305 \| SBF1 \| DISEASES 3662 \| IRF4 \| DISEASES 8110 \| DPF3 \| DISEASES 29126 \| CD274 \| DISEASES 3717 \| JAK2 \| DISEASES 399 \| RHOH \| DISEASES 9107 \| MTMR6 \| DISEASES 50808 \| AK3 \| DISEASES 83650 \| SLC35G5 \| DISEASES 11200 \| CHEK2 \| DISEASES 238 \| ALK \| DISEASES 83850 \| ESYT3 \| DISEASES 23779 \| ARHGAP8 \| DISEASES 340152 \| ZC3H12D \| DISEASES 3903 \| LAIR1 \| DISEASES 11262 \| SP140 \| DISEASES 7520 \| XRCC5 \| DISEASES 152137 \| CCDC50 \| DISEASES 7187 \| TRAF3 \| DISEASES 974 \| CD79B \| DISEASES 10018 \| BCL2L11 \| DISEASES 9130 \| FAM50A \| DISEASES 64333 \| ARHGAP9 \| DISEASES 347734 \| SLC35B2 \| DISEASES 3161 \| HMMR \| DISEASES 10517 \| FBXW10 \| DISEASES 6387 \| CXCL12 \| DISEASES 57584 \| ARHGAP21 \| DISEASES 10521 \| DDX17 \| DISEASES 84433 \| CARD11 \| DISEASES 3676 \| ITGA4 \| DISEASES 7757 \| ZNF208 \| DISEASES 7913 \| DEK \| DISEASES 5609 \| MAP2K7 \| DISEASES 23532 \| PRAME \| DISEASES 1654 \| DDX3X \| DISEASES 5970 \| RELA \| DISEASES 7514 \| XPO1 \| DISEASES 8115 \| TCL1A \| DISEASES 5150 \| PDE7A \| DISEASES 7852 \| CXCR4 \| DISEASES 9938 \| ARHGAP25 \| DISEASES 501 \| ALDH7A1 \| DISEASES 3384 \| ICAM2 \| DISEASES 3718 \| JAK3 \| DISEASES 57636 \| ARHGAP23 \| DISEASES 59339 \| PLEKHA2 \| DISEASES 1029 \| CDKN2A \| DISEASES 83876 \| MRO \| DISEASES 56616 \| DIABLO \| DISEASES 960 \| CD44 \| DISEASES 3702 \| ITK \| DISEASES 7124 \| TNF \| DISEASES 2352 \| FOLR3 \| DISEASES 5795 \| PTPRJ \| DISEASES 387 \| RHOA \| DISEASES 7072 \| TIA1 \| DISEASES 4615 \| MYD88 \| DISEASES 4049 \| LTA \| DISEASES 5923 \| RASGRF1 \| DISEASES 7266 \| DNAJC7 \| DISEASES 29125 \| C11orf21 \| DISEASES 55289 \| ACOXL \| DISEASES 9734 \| HDAC9 \| DISEASES 3451 \| IFNA17 \| DISEASES 3586 \| IL10 \| DISEASES 5527 \| PPP2R5C \| DISEASES 1945 \| EFNA4 \| DISEASES 118471 \| PRAP1 \| DISEASES 221443 \| OARD1 \| DISEASES 4193 \| MDM2 \| DISEASES 120526 \| DNAJC24 \| DISEASES 23089 \| PEG10 \| DISEASES 91227 \| GGTLC2 \| DISEASES 30816 \| ERVW-1 \| DISEASES 127933 \| UHMK1 \| DISEASES 4345 \| CD200 \| DISEASES 573 \| BAG1 \| DISEASES 220107 \| DLEU7 \| DISEASES 51428 \| DDX41 \| DISEASES 4067 \| LYN \| DISEASES 4603 \| MYBL1 \| DISEASES 100423062 \| IGLL5 \| DISEASES 8539 \| API5 \| DISEASES 917 \| CD3G \| DISEASES 56413 \| LTB4R2 \| DISEASES 28970 \| C11orf54 \| DISEASES 57476 \| GRAMD1B \| DISEASES 5977 \| DPF2 \| DISEASES 930 \| CD19 \| DISEASES 3684 \| ITGAM \| DISEASES 5027 \| P2RX7 \| DISEASES 317 \| APAF1 \| DISEASES 567 \| B2M \| DISEASES 55239 \| OGFOD1 \| DISEASES 26156 \| RSL1D1 \| DISEASES 6209 \| RPS15 \| DISEASES 7409 \| VAV1 \| DISEASES 104355217 \| ERICD \| DISEASES 104326057 \| GACAT1 \| DISEASES 104797537 \| GACAT3 \| DISEASES 100885779 \| LINC-ROR \| DISEASES 407975 \| MIR17HG \| DISEASES 677814 \| SNORA31 \| DISEASES 100337591 \| SNORA70F \| DISEASES 26821 \| SNORA74A \| DISEASES 27004 \| TCL6 \| DISEASES 102659353 \| THRIL \| DISEASES 102800311 \| TP53COR1 \| DISEASES 100887755 \| TRERNA1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	251
Disease	chronic lymphocytic leukemia
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:1) HP:0005550 \| Chronic lymphatic leukemia
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:102) HP:0002665 \| Lymphoma \| 17 HP:0001909 \| Leukemia \| 15 HP:0002664 \| Neoplasia \| 12 HP:0001903 \| Anemia \| 9 HP:0001878 \| Haemolytic anaemia \| 7 HP:0012115 \| Liver inflammation \| 7 HP:0001873 \| Low platelet count \| 6 HP:0030731 \| Carcinoma \| 6 HP:0001890 \| Autoimmune hemolytic anemia \| 5 HP:0012191 \| B-cell lymphoma \| 5 HP:0002716 \| Lymph node hyperplasia \| 4 HP:0001973 \| Autoimmune thrombocytopenia \| 4 HP:0100827 \| Lymphocytosis \| 4 HP:0002721 \| Immunodeficiency \| 4 HP:0012324 \| Myeloid leukemia \| 4 HP:0005506 \| Chronic myeloid leukemia \| 3 HP:0000083 \| Renal insufficiency \| 3 HP:0002861 \| Melanoma \| 3 HP:0012189 \| Hodgkin disease \| 3 HP:0002719 \| infections, recurrent \| 2 HP:0012190 \| T cell lymphoma \| 2 HP:0200084 \| Giant cell hepatitis \| 2 HP:0001919 \| Acute renal failure \| 2 HP:0002090 \| Pneumonia \| 2 HP:0004808 \| Acute myelogenous leukemia \| 2 HP:0000123 \| Nephritis \| 2 HP:0010310 \| Chylothorax \| 2 HP:0005550 \| Chronic lymphatic leukemia \| 2 HP:0002352 \| Leukoencephalopathy \| 2 HP:0001970 \| Interstitial nephritis \| 2 HP:0002840 \| Lymphadenitis \| 2 HP:0003072 \| Hypercalcemia \| 2 HP:0002860 \| Squamous cell carcinoma \| 2 HP:0002633 \| Vasculitis \| 2 HP:0011034 \| Amyloid disease \| 2 HP:0012410 \| Pure red cell aplasia \| 1 HP:0002028 \| Chronic diarrhea \| 1 HP:0001025 \| Hives \| 1 HP:0005523 \| Lymphoproliferative disorder \| 1 HP:0001744 \| Splenomegaly \| 1 HP:0001297 \| Cerebral vascular events \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0006824 \| Cranial nerve palsy \| 1 HP:0002910 \| Elevated transaminases \| 1 HP:0001941 \| acidemia \| 1 HP:0005584 \| Renal cell carcinoma \| 1 HP:0000821 \| Underactive thyroid \| 1 HP:0004845 \| Acute monoblastic leukemia \| 1 HP:0002863 \| Myelodysplastic syndrome \| 1 HP:0002113 \| Pulmonary infiltrates \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0012156 \| Hemophagocytosis \| 1 HP:0006562 \| Viral hepatitis \| 1 HP:0012125 \| Prostate cancer \| 1 HP:0000112 \| Nephropathy \| 1 HP:0002383 \| Encephalitis \| 1 HP:0100533 \| Ocular inflammation \| 1 HP:0012315 \| Histiocytoma \| 1 HP:0004953 \| Abdominal aortic aneurysm \| 1 HP:0001138 \| Damaged optic nerve \| 1 HP:0012234 \| Agranulocytosis \| 1 HP:0003128 \| Lactic acidosis \| 1 HP:0001063 \| Acrocyanosis \| 1 HP:0004432 \| Agammaglobulinaemia \| 1 HP:0012578 \| Membranous glomerulonephritis \| 1 HP:0012490 \| Inflammation of fat tissue \| 1 HP:0004313 \| Decreased immunoglobulin level \| 1 HP:0001876 \| Low blood cell count \| 1 HP:0200034 \| Papule \| 1 HP:0001082 \| Cholecystitis \| 1 HP:0000096 \| Glomerulosclerosis \| 1 HP:0100495 \| Mastocytosis \| 1 HP:0004820 \| Acute myelomonocytic leukemia \| 1 HP:0001907 \| Thromboembolic disease \| 1 HP:0011947 \| Respiratory infection \| 1 HP:0012192 \| Cutaneous T-cell lymphoma \| 1 HP:0100532 \| Scleritis \| 1 HP:0001875 \| Neutropenia \| 1 HP:0001945 \| Fever \| 1 HP:0002202 \| Pleural effusion \| 1 HP:0004818 \| Paroxysmal nocturnal hemoglobinuria \| 1 HP:0001287 \| Meningitis \| 1 HP:0002014 \| Diarrhea \| 1 HP:0006775 \| Multiple myeloma \| 1 HP:0001399 \| Liver failure \| 1 HP:0001888 \| Lymphocytopenia \| 1 HP:0006554 \| Acute hepatic failure \| 1 HP:0011974 \| Myelofibrosis \| 1 HP:0000618 \| Blindness \| 1 HP:0012126 \| Gastric cancer \| 1 HP:0001402 \| Hepatocellular carcinoma \| 1 HP:0001009 \| Telangiectases \| 1 HP:0000097 \| focal glomerulosclerosis \| 1 HP:0004942 \| Aortic aneurysm \| 1 HP:0003641 \| Hemoglobin in urine \| 1 HP:0003003 \| Colon cancer \| 1 HP:0005435 \| Impaired T cell function \| 1 HP:0200029 \| Cutaneous vasculitis \| 1 HP:0001541 \| Ascites \| 1 HP:0000212 \| Gingival overgrowth \| 1 HP:0002617 \| Aneurysmal dilatation \| 1 HP:0012740 \| Papilloma \| 1

Disease ID	251
Disease	chronic lymphocytic leukemia
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:53) C0009450 \| infection \| 12 C0002871 \| anemia \| 7 C0002878 \| hemolytic anemia \| 6 C0021311 \| infections \| 6 C1516669 \| clonal evolution \| 6 C0002880 \| autoimmune hemolytic anemia \| 4 C0040034 \| thrombocytopenia \| 4 C0024302 \| large cell lymphoma \| 3 C0349631 \| richter's transformation \| 3 C0272286 \| immune thrombocytopenia \| 3 C0432408 \| trisomy 12 \| 3 C0035078 \| renal failure \| 3 C0023473 \| chronic myeloid leukemia \| 2 C0032285 \| pneumonia \| 2 C0041364 \| tumor lysis syndrome \| 2 C0021051 \| immunodeficiency \| 2 C0007137 \| squamous cell carcinoma \| 2 C0024205 \| lymphadenitis \| 2 C0002726 \| amyloidosis \| 2 C0850497 \| immune deficiency \| 2 C0023443 \| hairy cell leukemia \| 2 C0553723 \| cutaneous squamous cell carcinoma \| 2 C0948976 \| leukaemia cutis \| 2 C0349631 \| richter syndrome \| 2 C0020437 \| hypercalcemia \| 2 C0008733 \| chylothorax \| 2 C0023524 \| progressive multifocal leukoencephalopathy \| 2 C0699893 \| non-melanoma skin cancer \| 1 C0876991 \| hemophagocytosis \| 1 C1332225 \| aggressive lymphoma \| 1 C0025202 \| malignant melanoma \| 1 C0079746 \| plasmablastic lymphoma \| 1 C0034902 \| pure red cell aplasia \| 1 C1262091 \| lymphocytic infiltration \| 1 C0085436 \| cryptococcal meningitis \| 1 C0024198 \| lyme disease \| 1 C0349631 \| richter's syndrome \| 1 C0014541 \| epiglottitis \| 1 C0026986 \| myelodysplastic syndrome \| 1 C0004610 \| bacteremia \| 1 C0079731 \| b cell lymphoma \| 1 C0032227 \| pleural effusion \| 1 C0340961 \| acquired pure red cell aplasia \| 1 C0796095 \| c syndrome \| 1 C0242379 \| lung cancer \| 1 C0021053 \| immune dysfunction \| 1 C0007129 \| merkel cell carcinoma \| 1 C0042384 \| vasculitis \| 1 C0029132 \| optic neuropathy \| 1 C0085077 \| sweet syndrome \| 1 C0011991 \| diarrhea \| 1 C0376358 \| prostate cancer \| 1 C1332079 \| alk-positive anaplastic large cell lymphoma \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:249)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1036935	20062064	30827	CXXC1	umls:C0023434	GAD	[Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.]	0.002638474	2010	NA	18	50317164	A	G
rs1036935	20062064	4152	MBD1	umls:C0023434	GAD	[Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.]	0.002367032	2010	NA	18	50317164	A	G
rs1042522	17981213	4193	MDM2	umls:C0023434	BeFree	Although the p53 R72P SNPs and MDM2 SNP309 did not associate with any of the parameters studied, the BAX G125A SNPs was associated with a more advanced Binet stage at diagnosis, supporting a potential role for this variant in CLL disease progression.	0.019445464	2007	TP53	17	7676154	G	T,C
rs1042522	17981213	581	BAX	umls:C0023434	BeFree	Although the p53 R72P SNPs and MDM2 SNP309 did not associate with any of the parameters studied, the BAX G125A SNPs was associated with a more advanced Binet stage at diagnosis, supporting a potential role for this variant in CLL disease progression.	0.016621425	2007	TP53	17	7676154	G	T,C
rs1044873	24292274	3394	IRF8	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.122638474	2013	IRF8	16	85922065	C	T
rs1045485	19074885	1236	CCR7	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.009987267	2008	CASP8	2	201284866	G	C
rs1045485	19074885	4843	NOS2	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.006448592	2008	CASP8	2	201284866	G	C
rs1045485	19074885	902	CCNH	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.002638474	2008	CASP8	2	201284866	G	C
rs1045485	19074885	3603	IL16	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.005005506	2008	CASP8	2	201284866	G	C
rs1045485	19074885	841	CASP8	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.123995683	2008	CASP8	2	201284866	G	C
rs1045642	25586345	5243	ABCB1	umls:C0023434	BeFree	Different frequencies and effects of ABCB1 T3435C polymorphism on clinical and laboratory features of B cell chronic lymphocytic leukemia in Kurdish patients.	0.008338753	2014	ABCB1	7	87509329	A	T,G
rs1045642	20496015	5243	ABCB1	umls:C0023434	BeFree	MDR-1 polymorphisms (G2677T and C3435T) in B-chronic lymphocytic leukemia: an impact on susceptibility and prognosis.	0.008338753	2011	ABCB1	7	87509329	A	T,G
rs1045642	17085864	5243	ABCB1	umls:C0023434	BeFree	MDR1 (ABCB1) gene polymorphism C3435T is associated with P-glycoprotein activity in B-cell chronic lymphocytic leukemia.	0.008338753	2006	ABCB1	7	87509329	A	T,G
rs1057035	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DICER1	14	95087805	T	C
rs1057035	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DICER1	14	95087805	T	C
rs1057035	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	DICER1	14	95087805	T	C
rs1057035	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DICER1	14	95087805	T	C
rs1057035	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DICER1	14	95087805	T	C
rs1057035	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DICER1	14	95087805	T	C
rs1057035	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DICER1	14	95087805	T	C
rs1057035	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	DICER1	14	95087805	T	C
rs10936599	24292274	55892	MYNN	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.12	2013	MYNN	3	169774313	C	T
rs10958369	21659360	4986	OPRK1	umls:C0023434	GAD	[Our findings provide evidence that genetic variation is a determinant of progression-free survival of patients with chronic lymphocytic leukemia. Specific associations warrant further analyses.]	0.002367032	2011	NA	8	53497648	G	A
rs11083846	18758461	25865	PRKD2	umls:C0023434	GWASCAT	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.24973957	2008	PRKD2	19	46704397	G	A
rs11083846	18758461	11262	SP140	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.248186863	2008	PRKD2	19	46704397	G	A
rs11083846	18758461	25865	PRKD2	umls:C0023434	GAD	[We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).]	0.24973957	2008	PRKD2	19	46704397	G	A
rs11083846	18758461	3662	IRF4	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.254278137	2008	PRKD2	19	46704397	G	A
rs11083846	18758461	25865	PRKD2	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.24973957	2008	PRKD2	19	46704397	G	A
rs11083846	18758461	29888	STRN4	umls:C0023434	GAD	[A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.]	0.004734064	2008	PRKD2	19	46704397	G	A
rs11158493	21659360	5529	PPP2R5E	umls:C0023434	GAD	[Our findings provide evidence that genetic variation is a determinant of progression-free survival of patients with chronic lymphocytic leukemia. Specific associations warrant further analyses.]	0.002367032	2011	PPP2R5E	14	63486804	C	T
rs113488022	22230299	673	BRAF	umls:C0023434	BeFree	Incidence of the BRAF V600E mutation in chronic lymphocytic leukaemia and prolymphocytic leukaemia.	0.001085767	2012	BRAF	7	140753336	A	T,G,C
rs113488022	25511147	673	BRAF	umls:C0023434	BeFree	The performance of the BRAF V600E-specific VE1 antibody was compared with that of allele-specific polymerase chain reaction (PCR) in 22 formalin-fixed, paraffin-embedded (FFPE) specimens with HCL involvement, along with nine splenic marginal zone lymphomas (SMZLs), 10 follicular lymphomas (FLs), 10 mantle cell lymphomas (MCLs), and 10 chronic lymphocytic leukemia/small lymphocytic lymphomas (CLL/SLLs).	0.001085767	2015	BRAF	7	140753336	A	T,G,C
rs11540654	17981213	581	BAX	umls:C0023434	BeFree	Although the p53 R72P SNPs and MDM2 SNP309 did not associate with any of the parameters studied, the BAX G125A SNPs was associated with a more advanced Binet stage at diagnosis, supporting a potential role for this variant in CLL disease progression.	0.016621425	2007	TP53	17	7676040	C	T,G,A
rs11540654	17981213	4193	MDM2	umls:C0023434	BeFree	Although the p53 R72P SNPs and MDM2 SNP309 did not associate with any of the parameters studied, the BAX G125A SNPs was associated with a more advanced Binet stage at diagnosis, supporting a potential role for this variant in CLL disease progression.	0.019445464	2007	TP53	17	7676040	C	T,G,A
rs11554290	9139869	4893	NRAS	umls:C0023434	BeFree	Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.	0.000814326	1997	NRAS	1	114713908	T	G,C,A
rs11614913	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	MIR196A2	12	53991815	C	T
rs11614913	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	MIR196A2	12	53991815	C	T
rs11614913	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	MIR196A2	12	53991815	C	T
rs11614913	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	MIR196A2	12	53991815	C	T
rs11614913	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	MIR196A2	12	53991815	C	T
rs11614913	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	MIR196A2	12	53991815	C	T
rs11614913	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	MIR196A2	12	53991815	C	T
rs11614913	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	MIR196A2	12	53991815	C	T
rs11668878	20062064	79147	FKRP	umls:C0023434	GAD	[Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.]	0.002367032	2010	SLC1A5	19	46765116	G	T
rs1168987	21659360	84312	BRMS1L	umls:C0023434	GAD	[Our findings provide evidence that genetic variation is a determinant of progression-free survival of patients with chronic lymphocytic leukemia. Specific associations warrant further analyses.]	0.002367032	2011	NA	14	35928474	C	T
rs11866002	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	CNOT1	16	58553833	C	T
rs11866002	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	CNOT1	16	58553833	C	T
rs11866002	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	CNOT1	16	58553833	C	T
rs11866002	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	CNOT1	16	58553833	C	T
rs11866002	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	CNOT1	16	58553833	C	T
rs11866002	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	CNOT1	16	58553833	C	T
rs11866002	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	CNOT1	16	58553833	C	T
rs11866002	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	CNOT1	16	58553833	C	T
rs121913237	9139869	4893	NRAS	umls:C0023434	BeFree	Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.	0.000814326	1997	NRAS	1	114716126	C	T,G,A
rs121913250	9139869	4893	NRAS	umls:C0023434	BeFree	Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.	0.000814326	1997	NRAS	1	114716127	C	T,G,A
rs121913507	18448146	947	CD34	umls:C0855095	BeFree	The KIT mutation D816V was detected in sorted CD34(+) cells and unfractionated marrow cells but not in CD5(+) SLL cells, confirming the coexistence of 2 distinct neoplasms.	0.000271442	2008	KIT	4	54733155	A	T
rs13181	22739018	2068	ERCC2	umls:C0023434	BeFree	These preliminary data suggest a possible modifying role of Lys751Gln XPD polymorphism for the development of CLL, expecially in radiation-exposed persons.	0.005276948	2012	ERCC2;KLC3	19	45351661	T	A,G
rs13181	19484764	7515	XRCC1	umls:C0023434	BeFree	Moreover, the clearest differences were found for rs13181 in ERCC2 and rs25487 in XRCC1 between CLL patients with unfavorable cytogenetic aberrations and controls.	0.005276948	2009	ERCC2;KLC3	19	45351661	T	A,G
rs13397985	22700719	3431	SP110	umls:C0023434	GWASCAT	Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.	0.124734064	2012	SP110;SP140	2	230226508	T	G
rs13397985	18758461	11262	SP140	umls:C0023434	GWASCAT	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.248186863	2008	SP110;SP140	2	230226508	T	G
rs13397985	18758461	11262	SP140	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.248186863	2008	SP110;SP140	2	230226508	T	G
rs13397985	18758461	11262	SP140	umls:C0023434	GAD	[We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).]	0.248186863	2008	SP110;SP140	2	230226508	T	G
rs13397985	23770605	11262	SP140	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.248186863	2013	SP110;SP140	2	230226508	T	G
rs13397985	23770605	3431	SP110	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.124734064	2013	SP110;SP140	2	230226508	T	G
rs13397985	18758461	3662	IRF4	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.254278137	2008	SP110;SP140	2	230226508	T	G
rs13397985	18758461	3431	SP110	umls:C0023434	GWASCAT	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	0.124734064	2008	SP110;SP140	2	230226508	T	G
rs13397985	18758461	25865	PRKD2	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.24973957	2008	SP110;SP140	2	230226508	T	G
rs13397985	24292274	11262	SP140	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.248186863	2013	SP110;SP140	2	230226508	T	G
rs13397985	24292274	3431	SP110	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.124734064	2013	SP110;SP140	2	230226508	T	G
rs13397985	22700719	11262	SP140	umls:C0023434	GWASCAT	Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.	0.248186863	2012	SP110;SP140	2	230226508	T	G
rs13397985	18758461	3431	SP110	umls:C0023434	GAD	[A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.]	0.124734064	2008	SP110;SP140	2	230226508	T	G
rs13401811	23770605	55289	ACOXL	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.247372538	2013	ACOXL	2	110858527	G	A
rs1439287	24292274	400997	LOC400997	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.12	2013	ACOXL;LOC400997	2	111114320	G	A
rs1439287	24292274	55289	ACOXL	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.247372538	2013	ACOXL;LOC400997	2	111114320	G	A
rs1494555	20952689	7124	TNF	umls:C0023434	BeFree	After stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma.	0.021235936	2011	IL7R	5	35871088	G	A
rs16976734	24292274	64864	RFX7	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.12	2013	RFX7	15	56090097	A	G
rs17028658	19074885	902	CCNH	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.002638474	2008	ANKS1B	12	98738334	T	C
rs17028658	19074885	4843	NOS2	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.006448592	2008	ANKS1B	12	98738334	T	C
rs17028658	19074885	3603	IL16	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.005005506	2008	ANKS1B	12	98738334	T	C
rs17028658	19074885	841	CASP8	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.123995683	2008	ANKS1B	12	98738334	T	C
rs17028658	19074885	1236	CCR7	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.009987267	2008	ANKS1B	12	98738334	T	C
rs17246404	24292274	25913	POT1	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.240542884	2013	POT1	7	124822607	C	A,T
rs17483466	22700719	55289	ACOXL	umls:C0023434	GWASCAT	Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.	0.247372538	2012	ACOXL;LOC105373556	2	111039881	A	G
rs17483466	18758461	3662	IRF4	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.254278137	2008	ACOXL;LOC105373556	2	111039881	A	G
rs17483466	18758461	25865	PRKD2	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.24973957	2008	ACOXL;LOC105373556	2	111039881	A	G
rs17483466	18758461	55289	ACOXL	umls:C0023434	GAD	[A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.]	0.247372538	2008	ACOXL;LOC105373556	2	111039881	A	G
rs17483466	18758461	11262	SP140	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.248186863	2008	ACOXL;LOC105373556	2	111039881	A	G
rs17483466	18758461	55289	ACOXL	umls:C0023434	GWASCAT	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	0.247372538	2008	ACOXL;LOC105373556	2	111039881	A	G
rs17483466	23770605	55289	ACOXL	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.247372538	2013	ACOXL;LOC105373556	2	111039881	A	G
rs17483466	18758461	10018	BCL2L11	umls:C0023434	GAD	[A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.]	0.008544182	2008	ACOXL;LOC105373556	2	111039881	A	G
rs17676986	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	SND1;SND1-IT1;LOC105375492	7	127996905	C	T
rs17676986	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	SND1;SND1-IT1;LOC105375492	7	127996905	C	T
rs17676986	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	SND1;SND1-IT1;LOC105375492	7	127996905	C	T
rs17676986	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	SND1;SND1-IT1;LOC105375492	7	127996905	C	T
rs17676986	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	SND1;SND1-IT1;LOC105375492	7	127996905	C	T
rs17676986	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	SND1;SND1-IT1;LOC105375492	7	127996905	C	T
rs17676986	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	SND1;SND1-IT1;LOC105375492	7	127996905	C	T
rs17676986	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	SND1;SND1-IT1;LOC105375492	7	127996905	C	T
rs1799782	22106831	7515	XRCC1	umls:C0023434	BeFree	Investigation of Arg399Gln and Arg194Trp polymorphisms of the XRCC1 (x-ray cross-complementing group 1) gene and its correlation to sister chromatid exchange frequency in patients with chronic lymphocytic leukemia.	0.005276948	2012	XRCC1	19	43553422	G	A
rs1800682	24292274	59	ACTA2	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.12	2013	ACTA2;FAS	10	88990206	A	G
rs1800682	24292274	355	FAS	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.127891677	2013	ACTA2;FAS	10	88990206	A	G
rs1800890	19573080	3586	IL10	umls:C0023434	BeFree	We confirmed previous studies showing a polymorphism in the IL10 promoter (rs1800890/-3575T>A) to be associated with non-Hodgkin lymphoma, as this allele was found to be associated with both CLL and WM.	0.01272543	2009	IL10	1	206776020	A	T
rs1800890	19573080	3586	IL10	umls:C0023434	GAD	[We confirmed previous studies showing a polymorphism in the IL10 promoter (rs1800890/-3575T>A) to be associated with non-Hodgkin lymphoma, as this allele was found to be associated with both CLL and WM.]	0.01272543	2009	IL10	1	206776020	A	T
rs1949733	21659360	152992	TRMT44	umls:C0023434	GAD	[Our findings provide evidence that genetic variation is a determinant of progression-free survival of patients with chronic lymphocytic leukemia. Specific associations warrant further analyses.]	0.002367032	2011	TRMT44	4	8501632	A	G
rs2032582	20496015	5243	ABCB1	umls:C0023434	BeFree	MDR-1 polymorphisms (G2677T and C3435T) in B-chronic lymphocytic leukemia: an impact on susceptibility and prognosis.	0.008338753	2011	ABCB1	7	87531302	A	T,C
rs20541	20952689	7124	TNF	umls:C0023434	BeFree	After stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma.	0.021235936	2011	IL13	5	132660272	A	G
rs210142	23770605	578	BAK1	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.122909916	2013	BAK1	6	33579060	T	C
rs210142	22700719	578	BAK1	umls:C0023434	GWASCAT	Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.	0.122909916	2012	BAK1	6	33579060	T	C
rs2114358	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	PVT1;MIR1206	8	128008933	G	A
rs2114358	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	PVT1;MIR1206	8	128008933	G	A
rs2114358	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	PVT1;MIR1206	8	128008933	G	A
rs2114358	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	PVT1;MIR1206	8	128008933	G	A
rs2114358	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	PVT1;MIR1206	8	128008933	G	A
rs2114358	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	PVT1;MIR1206	8	128008933	G	A
rs2114358	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	PVT1;MIR1206	8	128008933	G	A
rs2114358	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	PVT1;MIR1206	8	128008933	G	A
rs2228226	25352360	2735	GLI1	umls:C0023434	BeFree	Association between polymorphism of GLI1 gene SNP rs2228226 and chronic lymphocytic leukemia in Chinese population.	0.001085767	2014	GLI1;ARHGAP9	12	57472038	G	C
rs2230641	19074885	841	CASP8	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.123995683	2008	CCNH	5	87399457	A	T,G
rs2230641	19074885	3603	IL16	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.005005506	2008	CCNH	5	87399457	A	T,G
rs2230641	19074885	4843	NOS2	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.006448592	2008	CCNH	5	87399457	A	T,G
rs2230641	19074885	1236	CCR7	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.009987267	2008	CCNH	5	87399457	A	T,G
rs2230641	19074885	902	CCNH	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.002638474	2008	CCNH	5	87399457	A	T,G
rs2231142	21918980	9429	ABCG2	umls:C0023434	BeFree	Furthermore, a decreased risk of chronic lymphocytic leukemia (CLL) was associated with the ABCG2 rs2231142 variant (p = 0.0004), which could be replicated in an independent population.	0.001085767	2012	ABCG2	4	88131171	G	T
rs2236256	24292274	4988	OPRM1	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.122367032	2013	OPRM1;IPCEF1	6	154157305	C	A
rs2236256	24292274	26034	IPCEF1	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.12	2013	OPRM1;IPCEF1	6	154157305	C	A
rs2266690	19074885	841	CASP8	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.123995683	2008	NA	NA	NA	NA	NA
rs2266690	19074885	902	CCNH	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.002638474	2008	NA	NA	NA	NA	NA
rs2266690	19074885	3603	IL16	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.005005506	2008	NA	NA	NA	NA	NA
rs2266690	19074885	4843	NOS2	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.006448592	2008	NA	NA	NA	NA	NA
rs2266690	19074885	1236	CCR7	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.009987267	2008	NA	NA	NA	NA	NA
rs2305160	25227809	4862	NPAS2	umls:C0023434	BeFree	Lack of association of the NPAS2 gene Ala394Thr polymorphism (rs2305160:G>A) with risk of chronic lymphocytic leukemia.	0.000271442	2015	NPAS2;LOC101927142	2	100974842	A	G
rs2306029	21121903	4038	LRP4	umls:C0023434	GAD	[A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome.]	0.002638474	2011	LRP4;LRP4-AS1	11	46871557	T	A,C
rs2456449	20062064	9855	FARP2	umls:C0023434	BeFree	We identified four new risk loci for CLL at 2q37.3 (rs757978, FARP2; odds ratio (OR) = 1.39; P = 2.11 x 10(-9)), 8q24.21 (rs2456449; OR = 1.26; P = 7.84 x 10(-10)), 15q21.3 (rs7169431; OR = 1.36; P = 4.74 x 10(-7)) and 16q24.1 (rs305061; OR = 1.22; P = 3.60 x 10(-7)).	0.242638474	2010	NA	8	127180736	A	G
rs25487	19484764	7515	XRCC1	umls:C0023434	BeFree	Moreover, the clearest differences were found for rs13181 in ERCC2 and rs25487 in XRCC1 between CLL patients with unfavorable cytogenetic aberrations and controls.	0.005276948	2009	XRCC1	19	43551574	T	C
rs25487	22106831	7515	XRCC1	umls:C0023434	BeFree	Investigation of Arg399Gln and Arg194Trp polymorphisms of the XRCC1 (x-ray cross-complementing group 1) gene and its correlation to sister chromatid exchange frequency in patients with chronic lymphocytic leukemia.	0.005276948	2012	XRCC1	19	43551574	T	C
rs2779251	19074885	3603	IL16	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.005005506	2008	NOS2	17	27804300	G	A
rs2779251	19074885	1236	CCR7	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.009987267	2008	NOS2	17	27804300	G	A
rs2779251	19074885	902	CCNH	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.002638474	2008	NOS2	17	27804300	G	A
rs2779251	19074885	4843	NOS2	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.006448592	2008	NOS2	17	27804300	G	A
rs2779251	19074885	841	CASP8	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.123995683	2008	NOS2	17	27804300	G	A
rs2793086	21659360	27185	DISC1	umls:C0023434	GAD	[Our findings provide evidence that genetic variation is a determinant of progression-free survival of patients with chronic lymphocytic leukemia. Specific associations warrant further analyses.]	0.002367032	2011	DISC1;TSNAX-DISC1	1	231763958	T	G
rs305061	20062064	9855	FARP2	umls:C0023434	BeFree	We identified four new risk loci for CLL at 2q37.3 (rs757978, FARP2; odds ratio (OR) = 1.39; P = 2.11 x 10(-9)), 8q24.21 (rs2456449; OR = 1.26; P = 7.84 x 10(-10)), 15q21.3 (rs7169431; OR = 1.36; P = 4.74 x 10(-7)) and 16q24.1 (rs305061; OR = 1.22; P = 3.60 x 10(-7)).	0.242638474	2010	LOC105371388	16	85942053	C	T
rs305061	20062064	3394	IRF8	umls:C0023434	GAD	[Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.]	0.122638474	2010	LOC105371388	16	85942053	C	T
rs3136597	19573080	8743	TNFSF10	umls:C0023434	GAD	[Polymorphisms in TNFSF10 were associated with both CLL and WM.]	0.007805801	2009	TNFSF10	3	172510754	G	T
rs3136687	19074885	4843	NOS2	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.006448592	2008	CCR7	17	40561644	T	C
rs3136687	19074885	902	CCNH	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.002638474	2008	CCR7	17	40561644	T	C
rs3136687	19074885	1236	CCR7	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.009987267	2008	CCR7	17	40561644	T	C
rs3136687	19074885	841	CASP8	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.123995683	2008	CCR7	17	40561644	T	C
rs3136687	19074885	3603	IL16	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.005005506	2008	CCR7	17	40561644	T	C
rs31490	24292274	81037	CLPTM1L	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.12	2013	CLPTM1L	5	1344343	G	A,T
rs344550	22170086	714	C1QC	umls:C0023434	BeFree	Additionally, SNPs (C2 rs497309, A>C and C3 rs344550, G>C) in two complement genes were positively associated with marginal zone lymphoma (MZL) and C1QG was associated with CLL/SLL, but these results were based on a limited number of cases.	0.000271442	2012	C3	19	6682942	C	G
rs344550	22170086	347734	SLC35B2	umls:C0023434	BeFree	Additionally, SNPs (C2 rs497309, A>C and C3 rs344550, G>C) in two complement genes were positively associated with marginal zone lymphoma (MZL) and C1QG was associated with CLL/SLL, but these results were based on a limited number of cases.	0.012757768	2012	C3	19	6682942	C	G
rs3769825	23770605	841	CASP8	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.123995683	2013	CASP8	2	201246657	A	G
rs3805500	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA	5	31462870	G	A
rs3805500	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	DROSHA	5	31462870	G	A
rs3805500	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA	5	31462870	G	A
rs3805500	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA	5	31462870	G	A
rs3805500	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	DROSHA	5	31462870	G	A
rs3805500	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA	5	31462870	G	A
rs3805500	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA	5	31462870	G	A
rs3805500	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA	5	31462870	G	A
rs386493716	22106831	7515	XRCC1	umls:C0023434	BeFree	Investigation of Arg399Gln and Arg194Trp polymorphisms of the XRCC1 (x-ray cross-complementing group 1) gene and its correlation to sister chromatid exchange frequency in patients with chronic lymphocytic leukemia.	0.005276948	2012	NA	NA	NA	NA	NA
rs386545546	22106831	7515	XRCC1	umls:C0023434	BeFree	Investigation of Arg399Gln and Arg194Trp polymorphisms of the XRCC1 (x-ray cross-complementing group 1) gene and its correlation to sister chromatid exchange frequency in patients with chronic lymphocytic leukemia.	0.005276948	2012	NA	NA	NA	NA	NA
rs386626619	19816006	3717	JAK2	umls:C0023434	BeFree	Absence of the V617F JAK2 mutation in the lymphoid compartment in a patient with essential thrombocythemia and B-chronic lymphocytic leukemia and in two relatives with lymphoproliferative disorders.	0.007348794	2009	NA	NA	NA	NA	NA
rs386626619	22884083	3717	JAK2	umls:C0023434	BeFree	JAK2 V617F positive essential thrombocythemia developing in a patient with CD5⁻ chronic lymphocytic leukemia.	0.007348794	2012	NA	NA	NA	NA	NA
rs386626619	22890406	3717	JAK2	umls:C0023434	BeFree	In 4 previously reported patients with JAK2(V617F)-positive Ph(-) MPN and B-CLL there was no definitive proof of JAK2(V617F) mutation in B-CLL cells, although this was suggested in 1 patient.	0.007348794	2012	NA	NA	NA	NA	NA
rs387907272	23178471	4615	MYD88	umls:C0023434	BeFree	Recurrent L265P mutation of myeloid differentiation primary response gene 88 (MYD88) has been identified in a proportion of diffuse large B-cell lymphoma (DLBCL) and chronic lymphocytic leukemia.	0.003257302	2013	MYD88	3	38141150	T	C
rs387907272	26230596	4615	MYD88	umls:C0023434	BeFree	Thus, pyrosequencing for the MYD88 L265P mutation demonstrates a high clinical sensitivity and specificity to distinguish LPL from MZL and CLL.	0.003257302	2015	MYD88	3	38141150	T	C
rs387907272	25819228	4615	MYD88	umls:C0023434	BeFree	MYD88 L265P was found in 49/51 (96%) LPL cases and in 1/13 (7·6%) MZL (splenic type), whereas all CLL samples remained negative.	0.003257302	2015	MYD88	3	38141150	T	C
rs387907272	24992174	4615	MYD88	umls:C0023434	BeFree	MYD88 L265P mutation has been reported in ∼90% of Waldenström's Macroglobulinemia (WM) patients and immunoglobulin M (IgM) monoclonal gammopathies of uncertain significance (MGUS), as well as in some cases of lymphoma and chronic lymphocytic leukemia.	0.003257302	2015	MYD88	3	38141150	T	C
rs391525	21131588	3394	IRF8	umls:C0023434	GWASCAT	Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.	0.122638474	2011	IRF8	16	85910833	A	G
rs438034	21659360	1063	CENPF	umls:C0023434	GAD	[Our findings provide evidence that genetic variation is a determinant of progression-free survival of patients with chronic lymphocytic leukemia. Specific associations warrant further analyses.]	0.002367032	2011	CENPF	1	214657274	A	G
rs4406737	23770605	355	FAS	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.127891677	2013	FAS;LOC105378417	10	88999967	A	G
rs4505265	19074885	3603	IL16	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.005005506	2008	NA	NA	NA	NA	NA
rs4505265	19074885	4843	NOS2	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.006448592	2008	NA	NA	NA	NA	NA
rs4505265	19074885	841	CASP8	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.123995683	2008	NA	NA	NA	NA	NA
rs4505265	19074885	1236	CCR7	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.009987267	2008	NA	NA	NA	NA	NA
rs4505265	19074885	902	CCNH	umls:C0023434	BeFree	After adjustment for multiple testing, we found a strong association between CLL risk and six genetic variants: CCNH (rs2266690, V270A), APAF1 (rs17028658, 3'region), IL16 (rs4505265, first intron), CASP8 (rs1045485, D302H), NOS2A (rs2779251, promoter), and CCR7 (rs3136687, intron 1).	0.002638474	2008	NA	NA	NA	NA	NA
rs497309	22170086	347734	SLC35B2	umls:C0023434	BeFree	Additionally, SNPs (C2 rs497309, A>C and C3 rs344550, G>C) in two complement genes were positively associated with marginal zone lymphoma (MZL) and C1QG was associated with CLL/SLL, but these results were based on a limited number of cases.	0.012757768	2012	C2	6	31924707	A	C
rs497309	22170086	714	C1QC	umls:C0023434	BeFree	Additionally, SNPs (C2 rs497309, A>C and C3 rs344550, G>C) in two complement genes were positively associated with marginal zone lymphoma (MZL) and C1QG was associated with CLL/SLL, but these results were based on a limited number of cases.	0.000271442	2012	C2	6	31924707	A	C
rs4987852	23770605	596	BCL2	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.297966465	2013	BCL2	18	63126688	T	C
rs4987855	23770605	596	BCL2	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.297966465	2013	BCL2	18	63126316	C	T
rs568408	20952689	7124	TNF	umls:C0023434	BeFree	After stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma.	0.021235936	2011	IL12A;IL12A-AS1	3	159995680	G	A
rs6449182	21121903	952	CD38	umls:C0023434	GAD	[A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome.]	0.070727741	2011	CD38	4	15778830	C	G
rs66554220	24362551	3135	HLA-G	umls:C0023434	BeFree	HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphism.	0.00953026	2015	NA	NA	NA	NA	NA
rs6785504	21659360	5028	P2RY1	umls:C0023434	GAD	[Our findings provide evidence that genetic variation is a determinant of progression-free survival of patients with chronic lymphocytic leukemia. Specific associations warrant further analyses.]	0.002367032	2011	NA	3	152954990	G	T
rs6858698	24292274	817	CAMK2D	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.12	2013	CAMK2D	4	113762688	G	C
rs6877842	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA;C5orf22	5	31532531	G	C
rs6877842	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	DROSHA;C5orf22	5	31532531	G	C
rs6877842	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA;C5orf22	5	31532531	G	C
rs6877842	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA;C5orf22	5	31532531	G	C
rs6877842	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA;C5orf22	5	31532531	G	C
rs6877842	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA;C5orf22	5	31532531	G	C
rs6877842	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	DROSHA;C5orf22	5	31532531	G	C
rs6877842	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	DROSHA;C5orf22	5	31532531	G	C
rs7121	17020971	2778	GNAS	umls:C0023434	BeFree	The GNAS1 T393C polymorphism is associated with disease progression and survival in chronic lymphocytic leukemia.	0.005634266	2006	GNAS	20	58903752	C	T
rs7121	18006055	2778	GNAS	umls:C0023434	BeFree	The GNAS1 T393C polymorphism and lack of clinical prognostic value in chronic lymphocytic leukemia.	0.005634266	2008	GNAS	20	58903752	C	T
rs7169431	20062064	4734	NEDD4	umls:C0023434	GAD	[Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.]	0.002367032	2010	NA	15	56048698	A	G
rs7169431	20062064	9855	FARP2	umls:C0023434	BeFree	We identified four new risk loci for CLL at 2q37.3 (rs757978, FARP2; odds ratio (OR) = 1.39; P = 2.11 x 10(-9)), 8q24.21 (rs2456449; OR = 1.26; P = 7.84 x 10(-10)), 15q21.3 (rs7169431; OR = 1.36; P = 4.74 x 10(-7)) and 16q24.1 (rs305061; OR = 1.22; P = 3.60 x 10(-7)).	0.242638474	2010	NA	15	56048698	A	G
rs7176508	18758461	6176	RPLP1	umls:C0023434	GAD	[A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.]	0.002367032	2008	NA	15	69726651	A	G
rs7176508	18758461	3662	IRF4	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.254278137	2008	NA	15	69726651	A	G
rs7176508	18758461	11262	SP140	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.248186863	2008	NA	15	69726651	A	G
rs7176508	18758461	25865	PRKD2	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.24973957	2008	NA	15	69726651	A	G
rs735665	18758461	3662	IRF4	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.254278137	2008	GRAMD1B	11	123490689	G	A
rs735665	18758461	11262	SP140	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.248186863	2008	GRAMD1B	11	123490689	G	A
rs735665	18758461	25865	PRKD2	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.24973957	2008	GRAMD1B	11	123490689	G	A
rs735665	24292274	57476	GRAMD1B	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.127101096	2013	GRAMD1B	11	123490689	G	A
rs735665	23770605	57476	GRAMD1B	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.127101096	2013	GRAMD1B	11	123490689	G	A
rs735665	18758461	79827	CLMP	umls:C0023434	GAD	[A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.]	0.002367032	2008	GRAMD1B	11	123490689	G	A
rs735665	18758461	57476	GRAMD1B	umls:C0023434	GAD	[A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.]	0.127101096	2008	GRAMD1B	11	123490689	G	A
rs735665	22700719	57476	GRAMD1B	umls:C0023434	GWASCAT	Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.	0.127101096	2012	GRAMD1B	11	123490689	G	A
rs735665	18758461	57476	GRAMD1B	umls:C0023434	GWASCAT	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	0.127101096	2008	GRAMD1B	11	123490689	G	A
rs757978	20062064	9855	FARP2	umls:C0023434	BeFree	We identified four new risk loci for CLL at 2q37.3 (rs757978, FARP2; odds ratio (OR) = 1.39; P = 2.11 x 10(-9)), 8q24.21 (rs2456449; OR = 1.26; P = 7.84 x 10(-10)), 15q21.3 (rs7169431; OR = 1.36; P = 4.74 x 10(-7)) and 16q24.1 (rs305061; OR = 1.22; P = 3.60 x 10(-7)).	0.242638474	2010	FARP2	2	241431686	C	T,A
rs757978	20062064	9855	FARP2	umls:C0023434	GAD	[We identified four new risk loci for CLL at 2q37.3 (rs757978, FARP2; odds ratio (OR) = 1.39; P = 2.11 x 10(-9)), 8q24.21 (rs2456449; OR = 1.26; P = 7.84 x 10(-10)), 15q21.3 (rs7169431; OR = 1.36; P = 4.74 x 10(-7)) and 16q24.1 (rs305061; OR = 1.22; P = 3.60 x 10(-7)).]	0.242638474	2010	FARP2	2	241431686	C	T,A
rs757978	23770605	9855	FARP2	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.242638474	2013	FARP2	2	241431686	C	T,A
rs77375493	22884083	3717	JAK2	umls:C0023434	BeFree	JAK2 V617F positive essential thrombocythemia developing in a patient with CD5⁻ chronic lymphocytic leukemia.	0.007348794	2012	JAK2;INSL6	9	5073770	G	A,T
rs77375493	19816006	3717	JAK2	umls:C0023434	BeFree	Absence of the V617F JAK2 mutation in the lymphoid compartment in a patient with essential thrombocythemia and B-chronic lymphocytic leukemia and in two relatives with lymphoproliferative disorders.	0.007348794	2009	JAK2;INSL6	9	5073770	G	A,T
rs77375493	22890406	3717	JAK2	umls:C0023434	BeFree	In 4 previously reported patients with JAK2(V617F)-positive Ph(-) MPN and B-CLL there was no definitive proof of JAK2(V617F) mutation in B-CLL cells, although this was suggested in 1 patient.	0.007348794	2012	JAK2;INSL6	9	5073770	G	A,T
rs783540	20062064	64506	CPEB1	umls:C0023434	GAD	[Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.]	0.122367032	2010	CPEB1	15	82585958	A	G
rs784567	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TARBP2;MAP3K12	12	53500681	G	A
rs784567	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	TARBP2;MAP3K12	12	53500681	G	A
rs784567	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	TARBP2;MAP3K12	12	53500681	G	A
rs784567	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TARBP2;MAP3K12	12	53500681	G	A
rs784567	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TARBP2;MAP3K12	12	53500681	G	A
rs784567	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TARBP2;MAP3K12	12	53500681	G	A
rs784567	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TARBP2;MAP3K12	12	53500681	G	A
rs784567	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TARBP2;MAP3K12	12	53500681	G	A
rs872071	23770605	3662	IRF4	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.254278137	2013	IRF4	6	411064	A	G
rs872071	18758461	3662	IRF4	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.254278137	2008	IRF4	6	411064	A	G
rs872071	24292274	3662	IRF4	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.254278137	2013	IRF4	6	411064	A	G
rs872071	18758461	3662	IRF4	umls:C0023434	GWASCAT	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.254278137	2008	IRF4	6	411064	A	G
rs872071	18758461	11262	SP140	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.248186863	2008	IRF4	6	411064	A	G
rs872071	18758461	3662	IRF4	umls:C0023434	GAD	[We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).]	0.254278137	2008	IRF4	6	411064	A	G
rs872071	22700719	3662	IRF4	umls:C0023434	GWASCAT	Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.	0.254278137	2012	IRF4	6	411064	A	G
rs872071	18758461	25865	PRKD2	umls:C0023434	BeFree	We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).	0.24973957	2008	IRF4	6	411064	A	G
rs872071	19804451	3662	IRF4	umls:C0023434	BeFree	We have recently shown that the IRF4 variant rs872071 influences CLL risk.	0.254278137	2010	IRF4	6	411064	A	G
rs898518	23770605	51176	LEF1	umls:C0023434	GWASCAT	Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.	0.241900093	2013	LEF1	4	108095668	C	A
rs926070	24292274	10665	C6orf10	umls:C0023434	GWASCAT	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.	0.12	2013	C6orf10;LOC101929163	6	32289789	G	A
rs9272535	21131588	3117	HLA-DQA1	umls:C0023434	GWASCAT	Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.	0.12	2011	HLA-DQA1	6	32638979	G	A
rs9611280	25793711	23019	CNOT1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TNRC6B	22	40156115	G	A
rs9611280	25793711	406973	MIR196A2	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TNRC6B	22	40156115	G	A
rs9611280	25793711	27044	SND1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TNRC6B	22	40156115	G	A
rs9611280	25793711	29102	DROSHA	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	TNRC6B	22	40156115	G	A
rs9611280	25793711	100302170	MIR1206	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TNRC6B	22	40156115	G	A
rs9611280	25793711	6896	TARBP2P	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TNRC6B	22	40156115	G	A
rs9611280	25793711	23112	TNRC6B	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000271442	2015	TNRC6B	22	40156115	G	A
rs9611280	25793711	23405	DICER1	umls:C0023434	BeFree	We found nine statistically significant associations with CLL risk after FDR correction, seven in miRNA processing genes (rs3805500 and rs6877842 in DROSHA, rs1057035 in DICER1, rs17676986 in SND1, rs9611280 in TNRC6B, rs784567 in TRBP and rs11866002 in CNOT1) and two in pre-miRNAs (rs11614913 in miR196a2 and rs2114358 in miR1206).	0.000542884	2015	TNRC6B	22	40156115	G	A
rs9808753	20952689	7124	TNF	umls:C0023434	BeFree	After stratification by common B-cell lymphoma subtypes, a significant interaction was observed for IFNGR2 (rs9808753 P(forinteraction) = .006), IL13 (rs20541 P(forinteraction) = .019), and IL7R (rs1494555 P(forinteraction) = .012) for marginal zone B-cell lymphoma; IL7R (rs1494555 P(forinteraction) = .017) for small lymphocytic lymphoma/chronic lymphocytic leukemia; and IL12A (rs568408 P(forinteraction) = .013) and TNF (1799724 P(forinteraction) = .04) for follicular lymphoma.	0.021235936	2011	IFNGR2	21	33415005	A	G
rs9883654	21659360	5028	P2RY1	umls:C0023434	GAD	[Our findings provide evidence that genetic variation is a determinant of progression-free survival of patients with chronic lymphocytic leukemia. Specific associations warrant further analyses.]	0.002367032	2011	NA	3	153004186	C	T

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:105)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	214830617	rs438034	A	G	rs438034	21659360	5.00E-06	NA	1.88	[1.44-2.46]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	rs438034-T	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
1	231899704	rs2793086	T	G	rs2793086	21659360	9.00E-06	NA	3.01	[1.51-6.01]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	rs2793086-C	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
2	37467264	rs2041840	T	C	rs2041840	24292274	9.00E-06	NA	1.2	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2041840-C	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	37596089	rs3770745	C	T	rs3770745	23770605	1.68E-08	NA	1.24	[1.15-1.33]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs3770745-T	Meta-Analysis	Research Support, N.I.H., Intramural	A
2	111616104	rs13401811	G	A	rs13401811	23770605	2.00E-18	NA	1.41	[1.30-1.52]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs13401811-G	Meta-Analysis	Research Support, N.I.H., Intramural	G
2	111797458	rs17483466	A	G	rs17483466	18758461	2.00E-10	NA	1.39	[1.25-1.53]	505 cases; 1,438 controls	NOPOP(1943)	ALL(1943)	NOPOP(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs17483466-G	Research Support, Non-U.S. Gov't	A	ACOXL
2	111797458	rs17483466	A	G	rs17483466	22700719	5.00E-09	NA	1.43	[1.27-1.61]	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
2	111797458	rs17483466	A	G	rs17483466	23770605	4.00E-17	NA	1.37	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs17483466-G	Meta-Analysis	Research Support, N.I.H., Intramural	A
2	111871897	rs1439287	G	A	rs1439287	24292274	5.00E-15	NA	1.37	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs1439287-A	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	201740268	rs11688943	T	C	rs11688943	23770605	8.90E-08	NA	1.19	[1.12-1.28]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs11688943-T	Meta-Analysis	Research Support, N.I.H., Intramural	T
2	202111380	rs3769825	A	G	rs3769825	23770605	3.00E-09	NA	1.19	[1.12-1.25]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs3769825-T	Meta-Analysis	Research Support, N.I.H., Intramural	C
2	202153078	rs1035142	T	G	rs1035142	24292274	7.61E-05	NA	1.18	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs1035142-T	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	231091223	rs13397985	T	G	rs13397985	18758461	6.00E-10	NA	1.41	[1.26-1.57]	505 cases; 1,438 controls	NOPOP(1943)	ALL(1943)	NOPOP(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs13397985-G	Research Support, Non-U.S. Gov't	T	SP140
2	231091223	rs13397985	T	G	rs13397985	22700719	2.00E-07	NA	1.39	[1.23-1.59]	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
2	231091223	rs13397985	T	G	rs13397985	23770605	1.00E-22	NA	1.45	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs13397985-G	Meta-Analysis	Research Support, N.I.H., Intramural	T
2	231091223	rs13397985	T	G	rs13397985	24292274	5.00E-13	NA	1.43	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs13397985-G	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	242192848	rs7578199	T	C	rs7578199	23770605	5.39E-07	NA	1.2	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7578199-T	Meta-Analysis	Research Support, N.I.H., Intramural	T
2	242371101	rs757978	C	T	rs757978	20062064	2.00E-09	NA	1.38	[1.25-1.56]	505 European cases; 1,438 European controls	European(1943)	ALL(1943)	EUR(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs757978-A	Research Support, Non-U.S. Gov't	G	FARP2
2	242371101	rs757978	C	T	rs757978	22700719	3.00E-06	NA	1.46	[1.25-1.72]	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs757978-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
2	242371101	rs757978	C	T	rs757978	23770605	1.00E-07	NA	1.29	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs757978-A	Meta-Analysis	Research Support, N.I.H., Intramural	G
2	242371101	rs757978	C	T	rs757978	24292274	3.47E-04	NA	1.25	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs757978-T	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	152672779	rs6785504	G	T	rs6785504	21659360	7.00E-06	NA	2.11	[1.51-2.94]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	rs6785504-T	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
3	152721975	rs9883654	C	T	rs9883654	21659360	2.00E-06	NA	2.2	[1.57-3.08]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	rs9883654-T	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
3	169492101	rs10936599	C	T	rs10936599	24292274	2.00E-09	NA	1.26	[1.17-1.35]	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs10936599-C	Meta-Analysis	Research Support, Non-U.S. Gov't	C
4	8503359	rs1949733	A	G	rs1949733	21659360	8.00E-07	NA	2.36	[1.60-3.47]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	rs1949733-A	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
4	109016824	rs898518	C	A	rs898518	23770605	4.00E-10	NA	1.2	[1.14-1.27]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs898518-A	Meta-Analysis	Research Support, N.I.H., Intramural	A
4	109026414	rs2003869	A	G	rs2003869	23770605	8.45E-08	NA	1.19	[1.12-1.27]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2003869-G	Meta-Analysis	Research Support, N.I.H., Intramural	G,A
4	114683844	rs6858698	G	C	rs6858698	24292274	3.00E-09	NA	1.31	[1.20-1.44]	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs6858698-C	Meta-Analysis	Research Support, Non-U.S. Gov't	G
5	1279790	rs10069690	C	T	rs10069690	23770605	1.92E-07	NA	1.19	[1.12-1.28]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs10069690-T	Meta-Analysis	Research Support, N.I.H., Intramural	T
5	1344458	rs31490	G	A	rs31490	24292274	2.00E-07	NA	1.18	[1.11-1.26]	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs31490-A	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	408079	rs1050976	C	T	rs1050976	23770605	5.83E-20	NA	1.33	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs1050976-T	Meta-Analysis	Research Support, N.I.H., Intramural	C
6	411064	rs872071	A	G	rs872071	18758461	2.00E-20	NA	1.54	NA	505 cases; 1,438 controls	NOPOP(1943)	ALL(1943)	NOPOP(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs872071-G	Research Support, Non-U.S. Gov't	A	IRF4
6	411064	rs872071	A	G	rs872071	22700719	8.00E-14	NA	1.47	[1.33-1.63]	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs872071-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
6	411064	rs872071	A	G	rs872071	23770605	6.00E-20	NA	1.33	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs872071-G	Meta-Analysis	Research Support, N.I.H., Intramural	A
6	411064	rs872071	A	G	rs872071	24292274	3.00E-16	NA	1.39	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs872071-G	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	417727	rs9378805	A	C	rs9378805	21131588	2.00E-06	NA	1.38	[1.20-1.58]	407 Caucasian cases; 296 Caucasian controls	Caucasian(703)	ALL(703)	EUR(703)	ALL(703)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs9378805-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
6	417727	rs9378805	A	C	rs9378805	22700719	3.22E-11	NA	NA	NA	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
6	32257566	rs926070	G	A	rs926070	24292274	4.00E-08	0.66	1.27	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs926070-A	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	32578082	rs674313	C	T	rs674313	21131588	7.00E-09	NA	1.69	[1.41-2.01]	407 Caucasian cases; 296 Caucasian controls	Caucasian(703)	ALL(703)	EUR(703)	ALL(703)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs674313-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
6	32606756	rs9272535	G	A	rs9272535	21131588	9.00E-08	NA	1.61	[1.35-1.92]	407 Caucasian cases; 296 Caucasian controls	Caucasian(703)	ALL(703)	EUR(703)	ALL(703)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs9272535-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
6	32611641	rs9273012	A	G	rs9273012	23770605	3.51E-06	NA	1.17	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs9273012-G	Meta-Analysis	Research Support, N.I.H., Intramural	A
6	32626272	rs9273363	C	A	rs9273363	23770605	2.00E-10	NA	1.24	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs9273363-A	Meta-Analysis	Research Support, N.I.H., Intramural	C
6	33540209	rs210134	A	G	rs210134	24292274	3.00E-06	NA	1.31	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs210134-G	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	33546837	rs210142	T	C	rs210142	22700719	9.00E-16	NA	1.4	[1.25-1.57]	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs210142-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
6	33546837	rs210142	T	C	rs210142	23770605	5.00E-08	NA	1.22	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs210142-C	Meta-Analysis	Research Support, N.I.H., Intramural	C
6	151907748	rs4869742	C	T	rs4869742	21540461	2.00E-06	NA	1.67	[1.35-2.04]	201 Korean ancestry cases; 497 Korean ancestry controls	Korean(698)	ALL(698)	ASN(698)	ALL(698)	Chronic myeloid leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:8552	chronic myeloid leukemia	D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive	EFOID:0000339	chronic myelogenous leukemia	Leukemia	rs4869742-T	Research Support, Non-U.S. Gov't	C	C6orf97
6	154478440	rs2236256	C	A	rs2236256	24292274	2.00E-10	NA	1.23	[1.15-1.30]	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2236256-C	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	124462661	rs17246404	C	T	rs17246404	24292274	3.00E-08	NA	1.22	[1.14-1.31]	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs17246404-C	Meta-Analysis	Research Support, Non-U.S. Gov't	C
8	54410208	rs10958369	G	A	rs10958369	21659360	2.00E-06	NA	2.33	[1.64-3.33]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	NA	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
8	103578874	rs2511714	T	G	rs2511714	23770605	5.00E-08	NA	1.19	[1.12-1.27]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2511714-G	Meta-Analysis	Research Support, N.I.H., Intramural	G
8	128188019	rs2466024	G	A	rs2466024	24292274	3.00E-06	NA	1.21	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2466024-A	Meta-Analysis	Research Support, Non-U.S. Gov't	A
8	128192981	rs2456449	A	G	rs2456449	20062064	8.00E-10	NA	1.26	[1.17-1.35]	505 European cases; 1,438 European controls	European(1943)	ALL(1943)	EUR(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2456449-G	Research Support, Non-U.S. Gov't	A	NA
8	128192981	rs2456449	A	G	rs2456449	22700719	6.31E-04	NA	NA	NA	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
8	128209820	rs2466032	T	C	rs2466032	23770605	1.65E-08	NA	1.21	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2466032-C	Meta-Analysis	Research Support, N.I.H., Intramural	T
8	128211229	rs2466035	T	C	rs2466035	23770605	2.00E-08	NA	1.21	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2466035-C	Meta-Analysis	Research Support, N.I.H., Intramural	C
9	22206987	rs1679013	C	T	rs1679013	23770605	1.00E-08	NA	1.19	[1.12-1.27]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs1679013-C	Meta-Analysis	Research Support, N.I.H., Intramural	C
9	22336996	rs1359742	G	C	rs1359742	23770605	6.08E-09	NA	1.2	[1.12-1.28]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs1359742-G	Meta-Analysis	Research Support, N.I.H., Intramural	C
9	105735195	rs1342899	C	T	rs1342899	21659360	8.00E-07	NA	3.13	[1.85-5.26]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	NA	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
10	90749963	rs1800682	A	G	rs1800682	24292274	2.00E-08	NA	1.25	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs1800682-A	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	90759613	rs2147420	A	G	rs2147420	23770605	3.10E-13	NA	1.26	[1.19-1.34]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2147420-G	Meta-Analysis	Research Support, N.I.H., Intramural	T
10	90759724	rs4406737	A	G	rs4406737	23770605	1.00E-14	NA	1.27	[1.19-1.33]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs4406737-G	Meta-Analysis	Research Support, N.I.H., Intramural	G
11	2311152	rs7944004	T	G	rs7944004	23770605	2.00E-10	NA	1.2	[1.13-1.27]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7944004-T	Meta-Analysis	Research Support, N.I.H., Intramural	T
11	2321095	rs2521269	C	A,G,T	rs2521269	23770605	7.23E-09	NA	1.2	[1.14-1.28]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2521269-C	Meta-Analysis	Research Support, N.I.H., Intramural	C
11	2322829	rs11022157	C	A	rs11022157	24292274	3.00E-06	NA	1.22	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs11022157-A	Meta-Analysis	Research Support, Non-U.S. Gov't	C
11	123361397	rs735665	G	A	rs735665	18758461	4.00E-12	NA	1.45	[1.31-1.61]	505 cases; 1,438 controls	NOPOP(1943)	ALL(1943)	NOPOP(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs735665-A	Research Support, Non-U.S. Gov't	G	NA
11	123361397	rs735665	G	A	rs735665	22700719	3.00E-12	NA	1.52	[1.35-1.72]	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs735665-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
11	123361397	rs735665	G	A	rs735665	23770605	4.00E-39	NA	1.62	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs735665-A	Meta-Analysis	Research Support, N.I.H., Intramural	G
11	123361397	rs735665	G	A	rs735665	24292274	4.00E-24	NA	1.64	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs735665-A	Meta-Analysis	Research Support, Non-U.S. Gov't	G
14	36397680	rs1168987	C	T	rs1168987	21659360	5.00E-06	NA	2.27	[0.31-0.63]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	rs1168987-A	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
14	63953522	rs11158493	C	T	rs11158493	21659360	9.00E-07	NA	2	[1.56-2.56]	356 European ancestary cases	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to antineoplastic agents	HPOID:0002664	Neoplasm	DOID:1040	chronic lymphocytic leukemia	D000970	Antineoplastic Agents	NA	NA	Leukemia	NA	Randomized Controlled Trial	Research Support, Non-U.S. Gov't	Clinical Trial, Phase III
15	40403657	rs8024033	C	G	rs8024033	23770605	2.71E-10	NA	1.22	[1.15-1.30]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs8024033-C	Meta-Analysis	Research Support, N.I.H., Intramural	G
15	40414116	rs8023845	G	T	rs8023845	24292274	2.00E-06	NA	1.27	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs8023845-G	Meta-Analysis	Research Support, Non-U.S. Gov't	G
15	56340896	rs7169431	A	G	rs7169431	20062064	5.00E-07	NA	1.36	[1.21-1.53]	505 European cases; 1,438 European controls	European(1943)	ALL(1943)	EUR(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7169431-A	Research Support, Non-U.S. Gov't	A,G	NA
15	56340896	rs7169431	A	G	rs7169431	22700719	2.65E-05	NA	NA	NA	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
15	56340896	rs7169431	A	G	rs7169431	23770605	1.72E-05	NA	1.27	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7169431-A	Meta-Analysis	Research Support, N.I.H., Intramural	A,G
15	56382295	rs16976734	A	G	rs16976734	24292274	4.00E-07	NA	1.36	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs16976734-G	Meta-Analysis	Research Support, Non-U.S. Gov't	A
15	56775597	rs11636802	A	G	rs11636802	23770605	2.00E-13	NA	1.41	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs11636802-G	Meta-Analysis	Research Support, N.I.H., Intramural	A
15	70018990	rs7176508	A	G	rs7176508	18758461	5.00E-12	NA	1.37	[1.26-1.50]	505 cases; 1,438 controls	NOPOP(1943)	ALL(1943)	NOPOP(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7176508-A	Research Support, Non-U.S. Gov't	G	NA
15	70018990	rs7176508	A	G	rs7176508	22700719	3.00E-11	NA	1.42	[1.28-1.58]	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7176508-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
15	70018990	rs7176508	A	G	rs7176508	23770605	1.00E-17	NA	1.32	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7176508-A	Meta-Analysis	Research Support, N.I.H., Intramural	G
15	70018990	rs7176508	A	G	rs7176508	24292274	8.00E-18	NA	1.42	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7176508-A	Meta-Analysis	Research Support, Non-U.S. Gov't	G
15	83254708	rs783540	A	G	rs783540	20062064	4.00E-06	NA	1.18	[1.10-1.27]	505 European cases; 1,438 European controls	European(1943)	ALL(1943)	EUR(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs783540-G	Research Support, Non-U.S. Gov't	A	CPEB1
15	83398315	rs7163848	C	T	rs7163848	24292274	7.00E-05	NA	0.22	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs7163848-C	Meta-Analysis	Research Support, Non-U.S. Gov't	C
16	85927814	rs391023	C	T	rs391023	23770605	5.00E-17	NA	1.33	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs391023-G	Meta-Analysis	Research Support, N.I.H., Intramural	A
16	85944439	rs391525	A	G	rs391525	21131588	3.00E-09	NA	1.56	[1.35-1.82]	407 Caucasian cases; 296 Caucasian controls	Caucasian(703)	ALL(703)	EUR(703)	ALL(703)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
16	85944439	rs391525	A	G	rs391525	22700719	5.40E-07	NA	NA	NA	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
16	85944823	rs2292982	T	G	rs2292982	23770605	4.76E-17	NA	1.33	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs2292982-A	Meta-Analysis	Research Support, N.I.H., Intramural	C
16	85955671	rs1044873	C	T	rs1044873	24292274	1.00E-09	NA	1.29	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs1044873-C	Meta-Analysis	Research Support, Non-U.S. Gov't	T
16	85975659	rs305061	C	T	rs305061	20062064	4.00E-07	NA	1.22	[1.12-1.32]	505 European cases; 1,438 European controls	European(1943)	ALL(1943)	EUR(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs305061-T	Research Support, Non-U.S. Gov't	C,T	NA
16	85975659	rs305061	C	T	rs305061	22700719	9.00E-08	NA	1.33	[1.20-1.49]	1,121 European ancestry cases; 3,745 European ancestry controls	European(4866)	ALL(4866)	EUR(4866)	ALL(4866)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
16	85975659	rs305061	C	T	rs305061	23770605	8.76E-06	NA	1.16	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs305061-T	Meta-Analysis	Research Support, N.I.H., Intramural	C,T
17	25541278	rs4795519	A	C	rs4795519	21540461	1.00E-12	NA	1.85	[1.56-2.17]	201 Korean ancestry cases; 497 Korean ancestry controls	Korean(698)	ALL(698)	ASN(698)	ALL(698)	Chronic myeloid leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:8552	chronic myeloid leukemia	D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive	EFOID:0000339	chronic myelogenous leukemia	Leukemia	rs4795519-C	Research Support, Non-U.S. Gov't	C	NA
18	47837796	rs12970172	T	C	rs12970172	23770605	5.06E-04	NA	1.15	NA	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs12970172-C	Meta-Analysis	Research Support, N.I.H., Intramural	T
18	47843534	rs1036935	A	G	rs1036935	20062064	2.00E-06	NA	1.22	[1.12-1.32]	505 European cases; 1,438 European controls	European(1943)	ALL(1943)	EUR(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs1036935-T	Research Support, Non-U.S. Gov't	C	NA
18	57568693	rs7240884	A	G	rs7240884	24292274	1.50E-05	NA	1.19	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
18	57622287	rs4368253	T	C	rs4368253	23770605	3.00E-08	NA	1.19	[1.12-1.27]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs4368253-C	Meta-Analysis	Research Support, N.I.H., Intramural	C
18	58037433	rs35748167	G	C	rs35748167	23770605	9.31E-09	NA	1.32	[1.19-1.43]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs35748167-G	Meta-Analysis	Research Support, N.I.H., Intramural	C
18	60793494	rs4987856	C	T	rs4987856	23770605	5.71E-11	NA	1.45	[1.30-1.61]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs4987856-C	Meta-Analysis	Research Support, N.I.H., Intramural	G
18	60793549	rs4987855	C	T	rs4987855	23770605	3.00E-12	NA	1.47	[1.32-1.61]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs4987855-G	Meta-Analysis	Research Support, N.I.H., Intramural	G
18	60793921	rs4987852	T	C	rs4987852	23770605	8.00E-11	NA	1.41	[1.27-1.56]	2,179 European ancestry cases; 6,221 European ancestry controls	European(8400)	ALL(8400)	EUR(8400)	ALL(8400)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	NA	Meta-Analysis	Research Support, N.I.H., Intramural	A
18	60793921	rs4987852	T	C	rs4987852	24292274	8.00E-05	NA	1.35	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs4987852-C	Meta-Analysis	Research Support, Non-U.S. Gov't	A
19	47207654	rs11083846	G	A	rs11083846	18758461	4.00E-09		1.35	[1.22-1.49]	505 cases; 1,438 controls	NOPOP(1943)	ALL(1943)	NOPOP(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs11083846-A	Research Support, Non-U.S. Gov't	G	PRKD2
19	47268373	rs11668878	G	T	rs11668878	20062064	4.00E-07	NA	1.37	[1.21-1.55]	505 European cases; 1,438 European controls	European(1943)	ALL(1943)	EUR(1943)	ALL(1943)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs11668878-T	Research Support, Non-U.S. Gov't	G	NA
19	47287507	rs3027957	T	C	rs3027957	24292274	1.25E-05	NA	1.25	NA	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs3027957-C	Meta-Analysis	Research Support, Non-U.S. Gov't	A
20	62341931	rs6062501	T	G	rs6062501	24292274	1.47E-05	NA	1.19	[1.10-1.29]	1,739 European ancestry cases; 5,199 European ancestry controls	European(6938)	ALL(6938)	EUR(6938)	ALL(6938)	Chronic lymphocytic leukemia	HPOID:0005550	Chronic lymphatic leukemia	DOID:1040	chronic lymphocytic leukemia	D015451	Leukemia, Lymphocytic, Chronic, B-Cell	EFOID:0000095	chronic lymphocytic leukemia	Leukemia	rs6062501-T	Meta-Analysis	Research Support, Non-U.S. Gov't	T

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:15)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0023434	arsenic trioxide	C006632	1327-53-3	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	20534739
C0023434	bendamustine hydrochloride	D000069461	-	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	18980985
C0023434	carbamazepine	D002220	298-46-4	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	marker/mechanism	1644161
C0023434	chlorambucil	D002699	305-03-3	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	15370247
C0023434	cladribine	D017338	4291-63-8	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	15360010
C0023434	cyclophosphamide	D003520	50-18-0	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	17008537
C0023434	pentostatin	D015649	53910-25-1	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	17008537
C0023434	medroxyprogesterone acetate	D017258	71-58-9	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	18923439
C0023434	methotrexate	D008727	1959/5/2	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	marker/mechanism	11908730
C0023434	methotrexate	D008727	1959/5/2	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	3812535
C0023434	mitoxantrone	D008942	65271-80-9	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	18172266
C0023434	phenytoin	D010672	57-41-0	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	marker/mechanism	1644161
C0023434	sirolimus	D020123	53123-88-9	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	12393642
C0023434	thalidomide	D013792	50-35-1	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	19373657
C0023434	theophylline	D013806	58-55-9	leukemia, lymphocytic, chronic, b-cell	MESH:D015451	therapeutic	15370247

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)