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Pediatric Disease Annotations & Medicines



   choriocarcinoma
  

Disease ID 782
Disease choriocarcinoma
Definition
A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
Synonym
[m]choriocarcinoma
[m]chorioepithelioma
chordocarcinoma
chordoepithelioma
chorioblastoma
choriocarcinoma (disorder)
choriocarcinoma (morphologic abnormality)
choriocarcinoma [disease/finding]
choriocarcinoma nos
choriocarcinoma, malignant
choriocarcinoma, no icd-o subtype
choriocarcinoma, no icd-o subtype (morphologic abnormality)
choriocarcinoma, no international classification of diseases for oncology subtype
choriocarcinoma, no international classification of diseases for oncology subtype (morphologic abnormality)
choriocarcinoma, nos
choriocarcinomas
chorioepithelioma
chorioepithelioma nos
chorionepithelioma
chorionic carcinoma
syncytioma
DOID
UMLS
C0008497
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:28)
C0001418  |  adenocarcinoma  |  7
C0032987  |  ectopic pregnancy  |  3
C0153676  |  lung metastasis  |  3
C0006142  |  breast cancer  |  2
C1145670  |  respiratory failure  |  1
C0684249  |  lung carcinoma  |  1
C0153676  |  lung metastases  |  1
C0334523  |  teratoma with malignant transformation  |  1
C0205698  |  undifferentiated carcinoma  |  1
C0279651  |  gallbladder adenocarcinoma  |  1
C0007121  |  bronchogenic carcinoma  |  1
C0279682  |  bladder adenocarcinoma  |  1
C0014038  |  encephalitis  |  1
C0205696  |  anaplastic carcinoma  |  1
C0035412  |  rhabdomyosarcoma  |  1
C0476089  |  endometrial carcinoma  |  1
C0030805  |  pemphigoid  |  1
C0494165  |  liver metastases  |  1
C0153676  |  pulmonary metastases  |  1
C0206701  |  serous carcinoma  |  1
C0024623  |  gastric cancer  |  1
C0678222  |  mammary carcinoma  |  1
C0279672  |  cervical adenocarcinoma  |  1
C0220650  |  brain metastases  |  1
C0034065  |  pulmonary embolism  |  1
C0476089  |  endometrial ca  |  1
C0678222  |  breast carcinoma  |  1
C0015397  |  ocular disease  |  1
Curated Gene(Waiting for update.)
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:324)
64150  |  DIO3OS  |  DISEASES
2101  |  ESRRA  |  DISEASES
3207  |  HOXA11  |  DISEASES
1634  |  DCN  |  DISEASES
5982  |  RFC2  |  DISEASES
9603  |  NFE2L3  |  DISEASES
6515  |  SLC2A3  |  DISEASES
634  |  CEACAM1  |  DISEASES
2249  |  FGF4  |  DISEASES
6583  |  SLC22A4  |  DISEASES
7022  |  TFAP2C  |  DISEASES
23368  |  PPP1R13B  |  DISEASES
7738  |  ZNF184  |  DISEASES
5714  |  PSMD8  |  DISEASES
3956  |  LGALS1  |  DISEASES
113791  |  PIK3IP1  |  DISEASES
3162  |  HMOX1  |  DISEASES
57167  |  SALL4  |  DISEASES
1522  |  CTSZ  |  DISEASES
5020  |  OXT  |  DISEASES
7076  |  TIMP1  |  DISEASES
4313  |  MMP2  |  DISEASES
3163  |  HMOX2  |  DISEASES
10423  |  CDIPT  |  DISEASES
23581  |  CASP14  |  DISEASES
7040  |  TGFB1  |  DISEASES
1048  |  CEACAM5  |  DISEASES
6822  |  SULT2A1  |  DISEASES
7980  |  TFPI2  |  DISEASES
4232  |  MEST  |  DISEASES
6198  |  RPS6KB1  |  DISEASES
3216  |  HOXB6  |  DISEASES
2798  |  GNRHR  |  DISEASES
3558  |  IL2  |  DISEASES
4848  |  CNOT2  |  DISEASES
113246  |  C12orf57  |  DISEASES
79923  |  NANOG  |  DISEASES
4012  |  LNPEP  |  DISEASES
2908  |  NR3C1  |  DISEASES
3336  |  HSPE1  |  DISEASES
6509  |  SLC1A4  |  DISEASES
9429  |  ABCG2  |  DISEASES
7043  |  TGFB3  |  DISEASES
1748  |  DLX4  |  DISEASES
3223  |  HOXC6  |  DISEASES
79441  |  HAUS3  |  DISEASES
3623  |  INHA  |  DISEASES
5266  |  PI3  |  DISEASES
1026  |  CDKN1A  |  DISEASES
6584  |  SLC22A5  |  DISEASES
10047  |  CST8  |  DISEASES
1773  |  DNASE1  |  DISEASES
5189  |  PEX1  |  DISEASES
3976  |  LIF  |  DISEASES
64151  |  NCAPG  |  DISEASES
7376  |  NR1H2  |  DISEASES
10462  |  CLEC10A  |  DISEASES
56923  |  NMUR2  |  DISEASES
891  |  CCNB1  |  DISEASES
54407  |  SLC38A2  |  DISEASES
8521  |  GCM1  |  DISEASES
2295  |  FOXF2  |  DISEASES
5460  |  POU5F1  |  DISEASES
1588  |  CYP19A1  |  DISEASES
5858  |  PZP  |  DISEASES
10403  |  NDC80  |  DISEASES
8140  |  SLC7A5  |  DISEASES
6532  |  SLC6A4  |  DISEASES
999  |  CDH1  |  DISEASES
10681  |  GNB5  |  DISEASES
4173  |  MCM4  |  DISEASES
3553  |  IL1B  |  DISEASES
9410  |  SNRNP40  |  DISEASES
943  |  TNFRSF8  |  DISEASES
4162  |  MCAM  |  DISEASES
4175  |  MCM6  |  DISEASES
4811  |  NID1  |  DISEASES
7067  |  THRA  |  DISEASES
6774  |  STAT3  |  DISEASES
11320  |  MGAT4A  |  DISEASES
2028  |  ENPEP  |  DISEASES
1950  |  EGF  |  DISEASES
7078  |  TIMP3  |  DISEASES
23598  |  PATZ1  |  DISEASES
55089  |  SLC38A4  |  DISEASES
2065  |  ERBB3  |  DISEASES
3480  |  IGF1R  |  DISEASES
1583  |  CYP11A1  |  DISEASES
5045  |  FURIN  |  DISEASES
1009  |  CDH11  |  DISEASES
284086  |  NEK8  |  DISEASES
58488  |  PCTP  |  DISEASES
1213  |  CLTC  |  DISEASES
7157  |  TP53  |  DISEASES
2064  |  ERBB2  |  DISEASES
29947  |  DNMT3L  |  DISEASES
207  |  AKT1  |  DISEASES
805  |  CALM2  |  DISEASES
10550  |  ARL6IP5  |  DISEASES
5921  |  RASA1  |  DISEASES
83890  |  SPATA9  |  DISEASES
1956  |  EGFR  |  DISEASES
3484  |  IGFBP1  |  DISEASES
2796  |  GNRH1  |  DISEASES
123  |  PLIN2  |  DISEASES
5047  |  PAEP  |  DISEASES
133  |  ADM  |  DISEASES
114571  |  SLC22A9  |  DISEASES
823  |  CAPN1  |  DISEASES
3948  |  LDHC  |  DISEASES
8872  |  CDC123  |  DISEASES
1420  |  CRYGC  |  DISEASES
678  |  ZFP36L2  |  DISEASES
2321  |  FLT1  |  DISEASES
79888  |  LPCAT1  |  DISEASES
1436  |  CSF1R  |  DISEASES
2040  |  STOM  |  DISEASES
5468  |  PPARG  |  DISEASES
57798  |  GATAD1  |  DISEASES
3815  |  KIT  |  DISEASES
11309  |  SLCO2B1  |  DISEASES
9114  |  ATP6V0D1  |  DISEASES
808  |  CALM3  |  DISEASES
2063  |  NR2F6  |  DISEASES
9437  |  NCR1  |  DISEASES
6777  |  STAT5B  |  DISEASES
3678  |  ITGA5  |  DISEASES
30818  |  KCNIP3  |  DISEASES
251  |  ALPPL2  |  DISEASES
308  |  ANXA5  |  DISEASES
1437  |  CSF2  |  DISEASES
64321  |  SOX17  |  DISEASES
5267  |  SERPINA4  |  DISEASES
201161  |  CENPV  |  DISEASES
124935  |  SLC43A2  |  DISEASES
55867  |  SLC22A11  |  DISEASES
5617  |  PRL  |  DISEASES
51082  |  POLR1D  |  DISEASES
3479  |  IGF1  |  DISEASES
5093  |  PCBP1  |  DISEASES
10655  |  DMRT2  |  DISEASES
8433  |  UTF1  |  DISEASES
5066  |  PAM  |  DISEASES
4176  |  MCM7  |  DISEASES
10855  |  HPSE  |  DISEASES
741  |  ZNHIT2  |  DISEASES
1444  |  CSHL1  |  DISEASES
5031  |  P2RY6  |  DISEASES
3265  |  HRAS  |  DISEASES
8884  |  SLC5A6  |  DISEASES
26259  |  FBXW8  |  DISEASES
8463  |  TEAD2  |  DISEASES
836  |  CASP3  |  DISEASES
641371  |  ACOT1  |  DISEASES
2523  |  FUT1  |  DISEASES
3952  |  LEP  |  DISEASES
6879  |  TAF7  |  DISEASES
3172  |  HNF4A  |  DISEASES
1601  |  DAB2  |  DISEASES
653499  |  LGALS7B  |  DISEASES
666  |  BOK  |  DISEASES
9153  |  SLC28A2  |  DISEASES
1442  |  CSH1  |  DISEASES
3291  |  HSD11B2  |  DISEASES
8630  |  HSD17B6  |  DISEASES
811  |  CALR  |  DISEASES
10229  |  COQ7  |  DISEASES
2274  |  FHL2  |  DISEASES
6657  |  SOX2  |  DISEASES
3927  |  LASP1  |  DISEASES
5494  |  PPM1A  |  DISEASES
286826  |  LIN9  |  DISEASES
3855  |  KRT7  |  DISEASES
6667  |  SP1  |  DISEASES
54059  |  YBEY  |  DISEASES
596  |  BCL2  |  DISEASES
51400  |  PPME1  |  DISEASES
5155  |  PDGFB  |  DISEASES
3953  |  LEPR  |  DISEASES
4496  |  MT1H  |  DISEASES
9573  |  GDF3  |  DISEASES
430  |  ASCL2  |  DISEASES
54101  |  RIPK4  |  DISEASES
4088  |  SMAD3  |  DISEASES
2689  |  GH2  |  DISEASES
11104  |  KATNA1  |  DISEASES
10948  |  STARD3  |  DISEASES
56910  |  STARD7  |  DISEASES
11282  |  MGAT4B  |  DISEASES
23583  |  SMUG1  |  DISEASES
1368  |  CPM  |  DISEASES
359787  |  DPPA3  |  DISEASES
5764  |  PTN  |  DISEASES
6776  |  STAT5A  |  DISEASES
9324  |  HMGN3  |  DISEASES
85360  |  SYDE1  |  DISEASES
4089  |  SMAD4  |  DISEASES
7159  |  TP53BP2  |  DISEASES
259197  |  NCR3  |  DISEASES
2066  |  ERBB4  |  DISEASES
9962  |  SLC23A2  |  DISEASES
1499  |  CTNNB1  |  DISEASES
9672  |  SDC3  |  DISEASES
9232  |  PTTG1  |  DISEASES
2624  |  GATA2  |  DISEASES
100132406  |  NBPF10  |  DISEASES
7005  |  TEAD3  |  DISEASES
6925  |  TCF4  |  DISEASES
801  |  CALM1  |  DISEASES
85569  |  GALP  |  DISEASES
5802  |  PTPRS  |  DISEASES
3177  |  SLC29A2  |  DISEASES
4097  |  MAFG  |  DISEASES
6714  |  SRC  |  DISEASES
5893  |  RAD52  |  DISEASES
23607  |  CD2AP  |  DISEASES
1735  |  DIO3  |  DISEASES
7004  |  TEAD4  |  DISEASES
7037  |  TFRC  |  DISEASES
2114  |  ETS2  |  DISEASES
3135  |  HLA-G  |  DISEASES
5599  |  MAPK8  |  DISEASES
4311  |  MME  |  DISEASES
4326  |  MMP17  |  DISEASES
6241  |  RRM2  |  DISEASES
6533  |  SLC6A6  |  DISEASES
114814  |  GNRHR2  |  DISEASES
6582  |  SLC22A2  |  DISEASES
4751  |  NEK2  |  DISEASES
8407  |  TAGLN2  |  DISEASES
103  |  ADAR  |  DISEASES
253738  |  EBF3  |  DISEASES
3283  |  HSD3B1  |  DISEASES
1081  |  CGA  |  DISEASES
1486  |  CTBS  |  DISEASES
1791  |  DNTT  |  DISEASES
3725  |  JUN  |  DISEASES
292  |  SLC25A5  |  DISEASES
2030  |  SLC29A1  |  DISEASES
7422  |  VEGFA  |  DISEASES
4318  |  MMP9  |  DISEASES
5328  |  PLAU  |  DISEASES
84879  |  MFSD2A  |  DISEASES
9436  |  NCR2  |  DISEASES
2516  |  NR5A1  |  DISEASES
1104  |  RCC1  |  DISEASES
7046  |  TGFBR1  |  DISEASES
1192  |  CLIC1  |  DISEASES
64078  |  SLC28A3  |  DISEASES
11074  |  TRIM31  |  DISEASES
3105  |  HLA-A  |  DISEASES
94027  |  CGB7  |  DISEASES
11332  |  ACOT7  |  DISEASES
4609  |  MYC  |  DISEASES
3963  |  LGALS7  |  DISEASES
84515  |  MCM8  |  DISEASES
190  |  NR0B1  |  DISEASES
2625  |  GATA3  |  DISEASES
7020  |  TFAP2A  |  DISEASES
5209  |  PFKFB3  |  DISEASES
1832  |  DSP  |  DISEASES
8644  |  AKR1C3  |  DISEASES
57593  |  EBF4  |  DISEASES
2103  |  ESRRB  |  DISEASES
1045  |  CDX2  |  DISEASES
1761  |  DMRT1  |  DISEASES
3875  |  KRT18  |  DISEASES
284217  |  LAMA1  |  DISEASES
2524  |  FUT2  |  DISEASES
250  |  ALPP  |  DISEASES
1443  |  CSH2  |  DISEASES
196410  |  METTL7B  |  DISEASES
2719  |  GPC3  |  DISEASES
374654  |  KIF7  |  DISEASES
2643  |  GCH1  |  DISEASES
174  |  AFP  |  DISEASES
221002  |  RASGEF1A  |  DISEASES
144195  |  SLC2A14  |  DISEASES
5609  |  MAP2K7  |  DISEASES
10281  |  DSCR4  |  DISEASES
23192  |  ATG4B  |  DISEASES
57504  |  MTA3  |  DISEASES
7018  |  TF  |  DISEASES
65250  |  C5orf42  |  DISEASES
1747  |  DLX3  |  DISEASES
8925  |  HERC1  |  DISEASES
2086  |  ERV3-1  |  DISEASES
3481  |  IGF2  |  DISEASES
1029  |  CDKN2A  |  DISEASES
3550  |  IK  |  DISEASES
8909  |  ENDOU  |  DISEASES
960  |  CD44  |  DISEASES
3908  |  LAMA2  |  DISEASES
946  |  SIGLEC6  |  DISEASES
64084  |  CLSTN2  |  DISEASES
94115  |  CGB8  |  DISEASES
26168  |  SENP3  |  DISEASES
374875  |  HSD11B1L  |  DISEASES
1028  |  CDKN1C  |  DISEASES
1945  |  EFNA4  |  DISEASES
1967  |  EIF2B1  |  DISEASES
143662  |  MUC15  |  DISEASES
6256  |  RXRA  |  DISEASES
30816  |  ERVW-1  |  DISEASES
405754  |  ERVFRD-1  |  DISEASES
2649  |  NR6A1  |  DISEASES
6949  |  TCOF1  |  DISEASES
100526737  |  RBM14-RBM4  |  DISEASES
54212  |  SNTG1  |  DISEASES
10687  |  PNMA2  |  DISEASES
9152  |  SLC6A5  |  DISEASES
6195  |  RPS6KA1  |  DISEASES
9820  |  CUL7  |  DISEASES
6510  |  SLC1A5  |  DISEASES
53349  |  ZFYVE1  |  DISEASES
5228  |  PGF  |  DISEASES
2079  |  ERH  |  DISEASES
567  |  B2M  |  DISEASES
9212  |  AURKB  |  DISEASES
199713  |  NLRP7  |  DISEASES
414778  |  HCG17  |  DISEASES
140828  |  LINC00261  |  DISEASES
100506757  |  LINC00629  |  DISEASES
84848  |  MIR503HG  |  DISEASES
Locus(Waiting for update.)
Disease ID 782
Disease choriocarcinoma
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:18)
HP:0030731  |  Carcinoma  |  7
HP:0002664  |  Neoplasia  |  6
HP:0012531  |  Pain  |  2
HP:0003002  |  Breast carcinoma  |  2
HP:0002204  |  Pulmonary embolism  |  1
HP:0012114  |  Endometrial carcinoma  |  1
HP:0002383  |  Encephalitis  |  1
HP:0012126  |  Gastric cancer  |  1
HP:0003764  |  Naevus  |  1
HP:0100758  |  Gangrene  |  1
HP:0100718  |  Uterine rupture  |  1
HP:0000790  |  Hematuria  |  1
HP:0002027  |  Abdominal pain  |  1
HP:0002859  |  Rhabdomyosarcoma  |  1
HP:0002878  |  Respiratory failure  |  1
HP:0030157  |  Flank pain  |  1
HP:0004947  |  Arteriovenous fistula  |  1
HP:0002170  |  Intracranial hemorrhage  |  1
Disease ID 782
Disease choriocarcinoma
Manually Symptom
UMLS  | Name(Total Manually Symptoms:39)
C2364133  |  infection
C1517567  |  intravascular metastasis
C1393529  |  vascular complications
C1145670  |  respiratory failure
C0948265  |  metabolic syndrome
C0752303  |  urological manifestation
C0686377  |  cns metastases
C0686377  |  central nervous system metastasis
C0686377  |  central nervous system metastases
C0555278  |  cerebral metastasis
C0555278  |  cerebral metastases
C0494165  |  liver metastasis
C0494165  |  hepatic metastasis
C0494165  |  hepatic metastases
C0334520  |  immature teratoma
C0220650  |  brain metastasis
C0220650  |  brain metastases
C0153687  |  skin metastasis
C0153687  |  skin metastases
C0153687  |  cutaneous metastasis
C0153685  |  renal metastasis
C0153685  |  renal metastases
C0153676  |  pulmonary metastasis
C0153676  |  pulmonary metastases
C0153676  |  lung metastasis
C0042755  |  virilization
C0042143  |  uterine rupture
C0042139  |  uterine perforation
C0040156  |  thyrotoxicosis
C0030472  |  paraneoplastic syndrome
C0020550  |  hyperthyroidism
C0019693  |  hiv infection
C0019343  |  herpes gestationis
C0019080  |  hemorrhage
C0017665  |  membranous glomerulonephritis
C0017181  |  gastrointestinal hemorrhage
C0013930  |  tumor embolus
C0002940  |  aneurysms
C0002940  |  aneurysm
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:9)
C0153676  |  lung metastasis  |  3
C0555278  |  cerebral metastasis  |  2
C0019080  |  hemorrhage  |  2
C0555278  |  cerebral metastases  |  1
C0153676  |  pulmonary metastases  |  1
C0220650  |  brain metastases  |  1
C0334520  |  immature teratoma  |  1
C1145670  |  respiratory failure  |  1
C0042143  |  uterine rupture  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:1)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0008497tretinoinD014212302-79-4choriocarcinomaMESH:D002822therapeutic16461808
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)