PedAM

Pediatric Disease Annotations & Medicines


	cervical adenocarcinoma

Disease ID	1815
Disease	cervical adenocarcinoma
Definition	An adenocarcinoma arising from the cervical epithelium. It accounts for approximately 15% of invasive cervical carcinomas. Increased numbers of sexual partners and human papillomavirus (HPV) infection are risk factors. Grossly, advanced cervical adenocarcinoma may present as an exophytic mass, an ulcerated lesion, or diffuse cervical enlargement. Microscopically, the majority of cervical adenocarcinomas are of the endocervical (mucinous) type.
Synonym	adenocarcinoma - cervix adenocarcinoma cervical cancer adenocarcinoma cervix adenocarcinoma cervix uteri adenocarcinoma of cervix adenocarcinoma of cervix (disorder) adenocarcinoma of cervix uteri adenocarcinoma of the cervix adenocarcinoma of the cervix uteri adenocarcinoma of the uterine cervix adenocarcinoma of uterine cervix adenocarcinomas cervical adenocarcinomas cervix cervical adenocarcinoma, nos cervical adenocarcinoma, not otherwise specified cervical cancer, adenocarcinoma cervix adenocarcinoma cervix cancer, adenocarcinoma cervix uteri adenocarcinoma uterine cervix adenocarcinoma uterine cervix cancer, adenocarcinoma
Orphanet	ORPHANET:213772
DOID	DOID:3702
UMLS	C0279672
SNOMED-CT	SNOMEDCT_US_2016_09_01:254887002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:6) C0149925 \| small cell carcinoma \| 1 C0008497 \| choriocarcinoma \| 1 C1333990 \| lynch syndrome \| 1 C0018552 \| hamartoma \| 1 C0686619 \| lymph node metastases \| 1 C0003857 \| arteriovenous malformation \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:144) 4830 \| NME1 \| DISEASES 54474 \| KRT20 \| DISEASES 51208 \| CLDN18 \| DISEASES 2099 \| ESR1 \| DISEASES 5173 \| PDYN \| DISEASES 4833 \| NME4 \| DISEASES 343 \| AQP8 \| DISEASES 1048 \| CEACAM5 \| DISEASES 595 \| CCND1 \| DISEASES 3587 \| IL10RA \| DISEASES 7903 \| ST8SIA4 \| DISEASES 29094 \| LGALSL \| DISEASES 9479 \| MAPK8IP1 \| DISEASES 3229 \| HOXC13 \| DISEASES 1026 \| CDKN1A \| DISEASES 826 \| CAPNS1 \| DISEASES 7429 \| VIL1 \| DISEASES 1890 \| TYMP \| DISEASES 3852 \| KRT5 \| DISEASES 84674 \| CARD6 \| DISEASES 3845 \| KRAS \| DISEASES 6610 \| SMPD2 \| DISEASES 10241 \| CALCOCO2 \| DISEASES 10403 \| NDC80 \| DISEASES 3595 \| IL12RB2 \| DISEASES 3978 \| LIG1 \| DISEASES 7474 \| WNT5A \| DISEASES 9061 \| PAPSS1 \| DISEASES 7472 \| WNT2 \| DISEASES 6425 \| SFRP5 \| DISEASES 7157 \| TP53 \| DISEASES 2064 \| ERBB2 \| DISEASES 3756 \| KCNH1 \| DISEASES 26018 \| LRIG1 \| DISEASES 6423 \| SFRP2 \| DISEASES 319100 \| TAAR6 \| DISEASES 6581 \| SLC22A3 \| DISEASES 1956 \| EGFR \| DISEASES 5801 \| PTPRR \| DISEASES 81552 \| VOPP1 \| DISEASES 54971 \| BANP \| DISEASES 50848 \| F11R \| DISEASES 3588 \| IL10RB \| DISEASES 7307 \| U2AF1 \| DISEASES 563 \| AZGP1 \| DISEASES 5731 \| PTGER1 \| DISEASES 4009 \| LMX1A \| DISEASES 9076 \| CLDN1 \| DISEASES 5798 \| PTPRN \| DISEASES 57650 \| KIAA1524 \| DISEASES 4825 \| NKX6-1 \| DISEASES 308 \| ANXA5 \| DISEASES 64321 \| SOX17 \| DISEASES 9640 \| ZNF592 \| DISEASES 5347 \| PLK1 \| DISEASES 2923 \| PDIA3 \| DISEASES 94235 \| GNG8 \| DISEASES 147948 \| ZNF582 \| DISEASES 5734 \| PTGER4 \| DISEASES 8403 \| SOX14 \| DISEASES 3790 \| KCNS3 \| DISEASES 794 \| CALB2 \| DISEASES 51206 \| GP6 \| DISEASES 6596 \| HLTF \| DISEASES 9134 \| CCNE2 \| DISEASES 836 \| CASP3 \| DISEASES 6578 \| SLCO2A1 \| DISEASES 3642 \| INSM1 \| DISEASES 1604 \| CD55 \| DISEASES 2814 \| GP5 \| DISEASES 10397 \| NDRG1 \| DISEASES 3039 \| HBA1 \| DISEASES 84260 \| TCHP \| DISEASES 3909 \| LAMA3 \| DISEASES 6794 \| STK11 \| DISEASES 5241 \| PGR \| DISEASES 121227 \| LRIG3 \| DISEASES 51218 \| GLRX5 \| DISEASES 3214 \| HOXB4 \| DISEASES 3855 \| KRT7 \| DISEASES 6656 \| SOX1 \| DISEASES 277 \| AMY1B \| DISEASES 23542 \| MAPK8IP2 \| DISEASES 10539 \| GLRX3 \| DISEASES 7490 \| WT1 \| DISEASES 3838 \| KPNA2 \| DISEASES 10495 \| ENOX2 \| DISEASES 2042 \| EPHA3 \| DISEASES 9166 \| EBAG9 \| DISEASES 10524 \| KAT5 \| DISEASES 1447 \| CSN2 \| DISEASES 3167 \| HMX2 \| DISEASES 1499 \| CTNNB1 \| DISEASES 23373 \| CRTC1 \| DISEASES 3914 \| LAMB3 \| DISEASES 11186 \| RASSF1 \| DISEASES 841 \| CASP8 \| DISEASES 4311 \| MME \| DISEASES 10848 \| PPP1R13L \| DISEASES 9860 \| LRIG2 \| DISEASES 5743 \| PTGS2 \| DISEASES 3068 \| HDGF \| DISEASES 278 \| AMY1C \| DISEASES 276 \| AMY1A \| DISEASES 6005 \| RHAG \| DISEASES 3745 \| KCNB1 \| DISEASES 5728 \| PTEN \| DISEASES 7422 \| VEGFA \| DISEASES 113452 \| TMEM54 \| DISEASES 5457 \| POU4F1 \| DISEASES 26586 \| CKAP2 \| DISEASES 768 \| CA9 \| DISEASES 168400 \| DDX53 \| DISEASES 1045 \| CDX2 \| DISEASES 3486 \| IGFBP3 \| DISEASES 7310 \| ZRSR1 \| DISEASES 5650 \| KLK7 \| DISEASES 4291 \| MLF1 \| DISEASES 10401 \| PIAS3 \| DISEASES 23023 \| TMCC1 \| DISEASES 3122 \| HLA-DRA \| DISEASES 94025 \| MUC16 \| DISEASES 5075 \| PAX1 \| DISEASES 10581 \| IFITM2 \| DISEASES 10437 \| IFI30 \| DISEASES 28996 \| HIPK2 \| DISEASES 57057 \| TBX20 \| DISEASES 55743 \| CHFR \| DISEASES 9058 \| SLC13A2 \| DISEASES 1029 \| CDKN2A \| DISEASES 7849 \| PAX8 \| DISEASES 5076 \| PAX2 \| DISEASES 3594 \| IL12RB1 \| DISEASES 284111 \| SLC13A5 \| DISEASES 2195 \| FAT1 \| DISEASES 4588 \| MUC6 \| DISEASES 6424 \| SFRP4 \| DISEASES 84441 \| MAML2 \| DISEASES 6949 \| TCOF1 \| DISEASES 9152 \| SLC6A5 \| DISEASES 4586 \| MUC5AC \| DISEASES 63895 \| PIEZO2 \| DISEASES 81033 \| KCNH6 \| DISEASES 440900 \| LINC01191 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1815
Disease	cervical adenocarcinoma
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:7) HP:0002664 \| Neoplasia \| 6 HP:0012721 \| Venous malformations \| 1 HP:0100026 \| Arteriovenous malformation \| 1 HP:0100768 \| Choriocarcinoma \| 1 HP:0030731 \| Carcinoma \| 1 HP:0010566 \| Hamartoma \| 1 HP:0100615 \| Neoplasm of the ovary \| 1

Disease ID	1815
Disease	cervical adenocarcinoma
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:2)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs11575934	23280621	3594	IL12RB1	umls:C0279672	BeFree	Cervical adenocarcinoma risk was associated with the minor alleles of the IL10RA rs4252314 intronic SNP (OR=2.23, 95% CI=1.26-3.96) and IL12RB1 rs11575934 non-synonymous SNP (OR=1.51, 95% CI=1.12-2.05).	0.000271442	2013	IL12RB1	19	18075808	T	C
rs4252314	23280621	3594	IL12RB1	umls:C0279672	BeFree	Cervical adenocarcinoma risk was associated with the minor alleles of the IL10RA rs4252314 intronic SNP (OR=2.23, 95% CI=1.26-3.96) and IL12RB1 rs11575934 non-synonymous SNP (OR=1.51, 95% CI=1.12-2.05).	0.000271442	2013	IL10RA	11	117997802	A	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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