PedAM
Pediatric Disease Annotations & Medicines
| central sleep apnea | ||||
| Disease ID | 1574 |
|---|---|
| Disease | central sleep apnea |
| Definition | A condition associated with multiple episodes of sleep apnea which are distinguished from obstructive sleep apnea (SLEEP APNEA, OBSTRUCTIVE) by the complete cessation of efforts to breathe. This disorder is associated with dysfunction of central nervous system centers that regulate respiration. |
| Synonym | alveolar hypoventilation, central alveolar hypoventilations, central apnea central sleep apnea, central apnea, central sleep apnea, sleep, central apneas, central apneas, central sleep breathing, central sleep-disordered breathings, central sleep-disordered central alveolar hypoventilation central alveolar hypoventilation syndrome central apnea central apneas central apnoea central sleep apnea syndrome central sleep apneas central sleep apnoea central sleep disordered breathing central sleep-disordered breathing central sleep-disordered breathings hypoventilation, central alveolar hypoventilations, central alveolar sleep apnea central sleep apnea, central sleep apnea, central [disease/finding] sleep apnea, lethal central sleep apneas, central sleep disordered breathing, central sleep-disordered breathing, central sleep-disordered breathings, central |
| OMIM | |
| DOID | |
| UMLS | C0520680 |
| MeSH | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:16) C0018801 | heart failure | 22 C0264716 | chronic heart failure | 3 C0520679 | obstructive sleep apnea | 2 C0018802 | congestive heart failure | 2 C0018824 | valvular heart disease | 1 C0042075 | urological disorders | 1 C0022658 | kidney disease | 1 C0037315 | sleep apnea | 1 C1135191 | systolic heart failure | 1 C0027765 | neurological disorders | 1 C0431399 | joubert syndrome | 1 C0026769 | multiple sclerosis | 1 C0917796 | leber hereditary optic neuropathy | 1 C0027765 | neurological disorder | 1 C0018799 | heart disease | 1 C0085292 | stiff-person syndrome | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:43) 8929 | PHOX2B | DISEASES 1401 | CRP | DISEASES 1131 | CHRM3 | DISEASES 759 | CA1 | DISEASES 6521 | SLC4A1 | DISEASES 8647 | ABCB11 | DISEASES 402665 | IGLON5 | DISEASES 57724 | EPG5 | DISEASES 25836 | NIPBL | DISEASES 1360 | CPB1 | DISEASES 7547 | ZIC3 | DISEASES 4054 | LTBP3 | DISEASES 51305 | KCNK9 | DISEASES 6869 | TACR1 | DISEASES 2548 | GAA | DISEASES 3777 | KCNK3 | DISEASES 27129 | HSPB7 | DISEASES 1351 | COX8A | DISEASES 5032 | P2RY11 | DISEASES 4843 | NOS2 | DISEASES 10011 | SRA1 | DISEASES 2261 | FGFR3 | DISEASES 4128 | MAOA | DISEASES 60490 | PPCDC | DISEASES 57492 | ARID1B | DISEASES 6714 | SRC | DISEASES 26047 | CNTNAP2 | DISEASES 4000 | LMNA | DISEASES 50861 | STMN3 | DISEASES 9211 | LGI1 | DISEASES 1025 | CDK9 | DISEASES 4153 | MBL2 | DISEASES 3055 | HCK | DISEASES 4879 | NPPB | DISEASES 1906 | EDN1 | DISEASES 25820 | ARIH1 | DISEASES 55835 | CENPJ | DISEASES 344022 | NOTO | DISEASES 3550 | IK | DISEASES 10687 | PNMA2 | DISEASES 8914 | TIMELESS | DISEASES 101 | ADAM8 | DISEASES 55554 | KLK15 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1574 |
|---|---|
| Disease | central sleep apnea |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:1) HP:0010535 | Sleep apnea |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:12) HP:0001635 | Congestive heart failure | 23 HP:0012196 | Periodic respiration | 14 HP:0012531 | Pain | 2 HP:0011675 | Arrhythmias | 1 HP:0002870 | Obstructive sleep apnea | 1 HP:0005110 | Atrial fibrillation | 1 HP:0002871 | Central apnea | 1 HP:0002459 | Dysautonomia | 1 HP:0002791 | Under breathing | 1 HP:0001262 | Somnolence | 1 HP:0040213 | Hypopnea | 1 HP:0012532 | Chronic pain | 1 |
| Disease ID | 1574 |
|---|---|
| Disease | central sleep apnea |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0520680 | methadone | D008691 | 76-99-3 | sleep apnea, central | MESH:D020182 | marker/mechanism | 11255580 | ||
| C0520680 | morphine | D009020 | 57-27-2 | sleep apnea, central | MESH:D020182 | marker/mechanism | 2334618 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |