PedAM

Pediatric Disease Annotations & Medicines


	cauda equina syndrome

Disease ID	922
Disease	cauda equina syndrome
Definition	A rare neurologic disorder caused by impingement of the nerve roots of the cauda equina secondary to disc herniation, spinal stenosis, vertebral fracture, neoplasm or infection. Clinical signs may include bladder or bowel dysfunction, paresthesia and weakness of the lower extremities. The clinical course rapidly deteriorates and necessitates emergent surgical decompression to minimize risk of incontinence, sexual dysfunction and permanent paralysis.
Synonym	cauda equina syndrome (disorder) cauda equina syndrome (disorder) [ambiguous] cauda equina syndrome nos cauda equina syndrome nos (disorder) cauda equina syndrome, nos cauda equina syndromes lumbosacral syndrome syndrome cauda equina syndrome, cauda equina syndromes, cauda equina
DOID	DOID:11577
ICD10	ICD10CM:G83.4
UMLS	C0392548
SNOMED-CT	SNOMEDCT_US_2016_09_01:192970008
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:24) C0392548 \| cauda equina syndrome \| 33 C0003708 \| arachnoiditis \| 3 C0005697 \| neurogenic bladder \| 2 C0024299 \| lymphoma \| 2 C0038013 \| ankylosing spondylitis \| 2 C0038012 \| spondylitis \| 2 C0037944 \| spinal stenosis \| 2 C0018916 \| hemangioma \| 1 C0033953 \| sexual dysfunction \| 1 C0038016 \| spondylolisthesis \| 1 C0206093 \| primitive neuroectodermal tumor \| 1 C0025149 \| medulloblastoma \| 1 C0039730 \| thalassemia \| 1 C0334634 \| mantle cell lymphoma \| 1 C0270629 \| epidural abscess \| 1 C0751690 \| malignant peripheral nerve sheath tumor \| 1 C0041296 \| tuberculosis \| 1 C0078981 \| arachnoid cysts \| 1 C0078981 \| arachnoid cyst \| 1 C0034372 \| quadriplegia \| 1 C0029423 \| osteochondroma \| 1 C0079731 \| b-cell lymphoma \| 1 C0037753 \| sparganosis \| 1 C0030486 \| paraplegia \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:31) 1432 \| MAPK14 \| DISEASES 1959 \| EGR2 \| DISEASES 9572 \| NR1D1 \| DISEASES 2670 \| GFAP \| DISEASES 2521 \| FUS \| DISEASES 55850 \| USE1 \| DISEASES 5443 \| POMC \| DISEASES 5045 \| FURIN \| DISEASES 150094 \| SIK1 \| DISEASES 3948 \| LDHC \| DISEASES 29123 \| ANKRD11 \| DISEASES 2353 \| FOS \| DISEASES 5340 \| PLG \| DISEASES 836 \| CASP3 \| DISEASES 1103 \| CHAT \| DISEASES 467 \| ATF3 \| DISEASES 875 \| CBS \| DISEASES 2879 \| GPX4 \| DISEASES 4514 \| MT-CO3 \| DISEASES 3713 \| IVL \| DISEASES 3303 \| HSPA1A \| DISEASES 650 \| BMP2 \| DISEASES 1646 \| AKR1C2 \| DISEASES 6164 \| RPL34 \| DISEASES 146713 \| RBFOX3 \| DISEASES 2130 \| EWSR1 \| DISEASES 6559 \| SLC12A3 \| DISEASES 627 \| BDNF \| DISEASES 672 \| BRCA1 \| DISEASES 4359 \| MPZ \| DISEASES 567 \| B2M \| DISEASES
Locus	(Waiting for update.)

Disease ID	922
Disease	cauda equina syndrome
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:28) HP:0012531 \| Pain \| 5 HP:0003418 \| Back pain \| 3 HP:0002665 \| Lymphoma \| 2 HP:0003416 \| Spinal canal stenosis \| 2 HP:0000011 \| Neurogenic bladder \| 2 HP:0002664 \| Neoplasia \| 2 HP:0030431 \| Osteochondromas \| 1 HP:0000016 \| Urinary retention \| 1 HP:0002445 \| Paralysis of all four limbs \| 1 HP:0001028 \| Strawberry mark \| 1 HP:0010550 \| Paraplegia \| 1 HP:0100697 \| Neurofibrosarcoma \| 1 HP:0001288 \| Gait disturbance \| 1 HP:0040078 \| Axonal degeneration \| 1 HP:0003302 \| Spondylolithesis \| 1 HP:0100775 \| Dural ectasia \| 1 HP:0030065 \| Primitive neuroectodermal tumor \| 1 HP:0002885 \| Medulloblastoma \| 1 HP:0100702 \| Arachnoid cyst \| 1 HP:0004610 \| Narrow lumbar spinal canal \| 1 HP:0012191 \| B-cell lymphoma \| 1 HP:0002953 \| Vertebral compression fractures \| 1 HP:0009027 \| Foot drop \| 1 HP:0002366 \| Lower motor neuron disease \| 1 HP:0007340 \| Lower limb weakness \| 1 HP:0002948 \| Fusion of vertebral bodies \| 1 HP:0003690 \| Limb weakness \| 1 HP:0000020 \| Bladder incontinence \| 1

Disease ID	922
Disease	cauda equina syndrome
Manually Symptom	UMLS \| Name(Total Manually Symptoms:5) C0078981 \| arachnoid diverticula C0030200 \| intractable pain C0024031 \| lumbar pain C0015732 \| fecal incontinence C0003708 \| arachnoiditis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0003708 \| arachnoiditis \| 3 C0030200 \| intractable pain \| 1

Manually Genotype(Total Text Mining Genotypes:0)
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All Snps(Total Genotypes:0)
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GWASdb Annotation(Total Genotypes:0)
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GWASdb Snp Trait(Total Genotypes:0)
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Mapped by lexical matching(Total Items:0)
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Mapped by homologous gene(Total Items:0)
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Chemical(Total Drugs:0)
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FDA approved drug and dosage information(Total Drugs:0)
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FDA labeling changes(Total Drugs:0)
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