PedAM
Pediatric Disease Annotations & Medicines
| carotid artery thrombosis | ||||
| Disease ID | 1863 |
|---|---|
| Disease | carotid artery thrombosis |
| Definition | Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX. |
| Synonym | artery carotid thrombosis carotid artery thromboses carotid artery thrombosis (disorder) carotid artery thrombosis [disease/finding] carotid thrombosis thrombosis carotid thrombosis carotid artery thrombosis, carotid thrombosis, carotid artery |
| DOID | |
| UMLS | C0007274 |
| MeSH | |
| SNOMED-CT | |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:3) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:65) 1361 | CPB2 | DISEASES 3053 | SERPIND1 | DISEASES 4627 | MYH9 | DISEASES 1511 | CTSG | DISEASES 10544 | PROCR | DISEASES 5327 | PLAT | DISEASES 5054 | SERPINE1 | DISEASES 6404 | SELPLG | DISEASES 5624 | PROC | DISEASES 847 | CAT | DISEASES 5552 | SRGN | DISEASES 7408 | VASP | DISEASES 348 | APOE | DISEASES 967 | CD63 | DISEASES 7450 | VWF | DISEASES 3674 | ITGA2B | DISEASES 6416 | MAP2K4 | DISEASES 334 | APLP2 | DISEASES 6403 | SELP | DISEASES 10000 | AKT3 | DISEASES 3818 | KLKB1 | DISEASES 3827 | KNG1 | DISEASES 4240 | MFGE8 | DISEASES 6647 | SOD1 | DISEASES 5141 | PDE4A | DISEASES 10733 | PLK4 | DISEASES 170692 | ADAMTS18 | DISEASES 23576 | DDAH1 | DISEASES 5196 | PF4 | DISEASES 4846 | NOS3 | DISEASES 5028 | P2RY1 | DISEASES 64805 | P2RY12 | DISEASES 2147 | F2 | DISEASES 51206 | GP6 | DISEASES 5340 | PLG | DISEASES 7094 | TLN1 | DISEASES 6810 | STX4 | DISEASES 2529 | FUT7 | DISEASES 2149 | F2R | DISEASES 5034 | P4HB | DISEASES 2811 | GP1BA | DISEASES 2152 | F3 | DISEASES 2534 | FYN | DISEASES 6714 | SRC | DISEASES 51592 | TRIM33 | DISEASES 5336 | PLCG2 | DISEASES 23038 | WDTC1 | DISEASES 2058 | EPRS | DISEASES 462 | SERPINC1 | DISEASES 10451 | VAV3 | DISEASES 26036 | ZNF451 | DISEASES 953 | ENTPD1 | DISEASES 5900 | RALGDS | DISEASES 2159 | F10 | DISEASES 2155 | F7 | DISEASES 7056 | THBD | DISEASES 208 | AKT2 | DISEASES 5547 | PRCP | DISEASES 2876 | GPX1 | DISEASES 5270 | SERPINE2 | DISEASES 9948 | WDR1 | DISEASES 4067 | LYN | DISEASES 5027 | P2RX7 | DISEASES 388588 | SMIM1 | DISEASES 7409 | VAV1 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1863 |
|---|---|
| Disease | carotid artery thrombosis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | (Waiting for update.) |
| Disease ID | 1863 |
|---|---|
| Disease | carotid artery thrombosis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
Chemical(Total Drugs:2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0007274 | progesterone | D011374 | 57-83-0 | carotid artery thrombosis | MESH:D002341 | marker/mechanism | 8638876 | ||
| C0007274 | tranexamic acid | D014148 | 1197-18-8 | carotid artery thrombosis | MESH:D002341 | marker/mechanism | 63691 | ||
FDA approved drug and dosage information(Total Drugs:1) | ||||||||
|---|---|---|---|---|---|---|---|---|
| DiseaseID | Drug_name | active_ingredients | strength | Dosage Form/Route | Marketing Status | TE code | RLD | RS |
| MESH:D002341 | lysteda | tranexamic acid | 650MG | TABLET;ORAL | Prescription | AB | Yes | Yes |
FDA labeling changes(Total Drugs:1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DiseaseID | Pediatric_Labeling_Date | Trade_Name | Generic_Name_or_Proper_Name | Indications Studied | Label Changes Summary | Product Labeling | BPCA(B) | PREA(P) | BPCA(B) and PREA(P) | Pediatric Rule (R) | Sponsor | Pediatric Exclusivity Granted Date | NNPS |
| MESH:D002341 | 08/21/2013 | lysteda | tranexamic acid | Treatment of cyclic heavy menstrual bleeding | Indicated for women of reproductive age. It is not intended for use in premenarcheal girls Information on PK studyPostmarketing study | - | P | - | - | Ferring | - | FALSE' | - |