PedAM

Pediatric Disease Annotations & Medicines


	cardiogenic shock

Disease ID	959
Disease	cardiogenic shock
Definition	Shock resulting from diminution of cardiac output in heart disease.
Synonym	[d]cardiogenic shock [d]cardiogenic shock (context-dependent category) [d]cardiogenic shock (situation) [d]heart shock cardiocirculatory collapse cardiogenic shock (disorder) cardiovascular shock heart shock heart shocking shock cardiogenic shock heart shock, cardiogenic shock, cardiogenic [disease/finding]
Orphanet	ORPHANET:97292
ICD10	ICD10CM:R57.0
UMLS	C0036980
MeSH	D012770
SNOMED-CT	SNOMEDCT_US_2016_09_01:89138009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:69) C0027051 \| myocardial infarct \| 155 C0027051 \| myocardial infarction \| 154 C0155626 \| acute myocardial infarction \| 91 C0878544 \| cardiomyopathy \| 17 C0027059 \| myocarditis \| 14 C0018801 \| heart failure \| 8 C0027051 \| myocardial infarction (mi) \| 7 C0155626 \| acute mi \| 6 C0034063 \| pulmonary edema \| 5 C0014118 \| endocarditis \| 5 C0034065 \| pulmonary embolism \| 4 C0007193 \| dilated cardiomyopathy \| 4 C0031511 \| pheochromocytoma \| 4 C0022116 \| ischemia \| 3 C0040053 \| thrombus \| 3 C0007177 \| cardiac tamponade \| 2 C0018801 \| cardiac failure \| 2 C0007194 \| hypertrophic cardiomyopathy \| 2 C0031046 \| pericarditis \| 2 C1145670 \| respiratory failure \| 2 C0018802 \| congestive heart failure \| 2 C0155686 \| acute myocarditis \| 2 C0020538 \| hypertension \| 2 C1332850 \| primary cardiac lymphoma \| 1 C0264793 \| idiopathic dilated cardiomyopathy \| 1 C0268407 \| cardiac amyloidosis \| 1 C0008372 \| intrahepatic cholestasis \| 1 C0040053 \| thrombosis \| 1 C0022660 \| acute renal failure \| 1 C0878544 \| cardiomyopathies \| 1 C0264832 \| peripartum cardiomyopathy \| 1 C0042870 \| vitamin d defic \| 1 C0011570 \| depression \| 1 C0003507 \| aortic valve stenosis \| 1 C0018802 \| congestive cardiac failure \| 1 C0002726 \| amyloidosis \| 1 C0010073 \| coronary spasm \| 1 C0039730 \| thalassemia \| 1 C0262564 \| anterolateral myocardial infarction \| 1 C0030305 \| pancreatitis \| 1 C0020676 \| hypothyroid \| 1 C0020542 \| pulmonary hypertension \| 1 C0003504 \| aortic regurgitation \| 1 C0007194 \| obstructive cardiomyopathy \| 1 C0151744 \| myocardial ischemia \| 1 C0206141 \| hypereosinophilic syndrome \| 1 C0004245 \| av block \| 1 C0024299 \| lymphoma \| 1 C0242231 \| coronary artery stenosis \| 1 C0008728 \| churg-strauss syndrome \| 1 C0003507 \| aortic stenosis \| 1 C0026848 \| myopathy \| 1 C0007194 \| hypertrophic obstructive cardiomyopathy \| 1 C0023418 \| leukemia \| 1 C0005122 \| beriberi \| 1 C0011849 \| diabetes mellitus \| 1 C0040961 \| tricuspid regurgitation \| 1 C0027051 \| myocardial infarctions \| 1 C0042769 \| viral illness \| 1 C0035078 \| renal failure \| 1 C0010068 \| coronary disease \| 1 C0042870 \| vitamin d deficiency \| 1 C0020538 \| high blood pressure \| 1 C0011847 \| diabetes \| 1 C0031039 \| pericardial effusion \| 1 C0340305 \| inferior myocardial infarction \| 1 C0027051 \| cardiac infarction \| 1 C0035229 \| respiratory insufficiency \| 1 C0014121 \| infective endocarditis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:3) SOD2 \| 6648 \| CTD_human PLAT \| 5327 \| CTD_human EPO \| 2056 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	(Waiting for update.)
Locus	(Waiting for update.)

Disease ID	959
Disease	cardiogenic shock
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:69) HP:0001658 \| Myocardial infarction \| 66 HP:0001638 \| Cardiomyopathy \| 16 HP:0012819 \| Myocarditis \| 13 HP:0001635 \| Congestive heart failure \| 10 HP:0002615 \| Low blood pressure \| 5 HP:0100584 \| Endocarditis \| 5 HP:0001649 \| Tachycardia \| 5 HP:0012531 \| Pain \| 4 HP:0100598 \| Pulmonary oedema \| 4 HP:0002045 \| Abnormally low body temperature \| 4 HP:0002666 \| Pheochromocytoma \| 4 HP:0000969 \| Dropsy \| 4 HP:0001644 \| Congestive cardiomyopathy \| 3 HP:0002204 \| Pulmonary embolism \| 3 HP:0001941 \| acidemia \| 3 HP:0011665 \| Takotsubo cardiomyopathy \| 3 HP:0011675 \| Arrhythmias \| 3 HP:0001695 \| Cardiac arrest \| 3 HP:0001942 \| Metabolic acidosis \| 3 HP:0001708 \| Impaired right ventricular function \| 3 HP:0100749 \| Thoracic pain \| 3 HP:0000822 \| Hypertension \| 2 HP:0001650 \| Valvular aortic stenosis \| 2 HP:0004756 \| Ventricular tachycardia \| 2 HP:0100806 \| Sepsis \| 2 HP:0001639 \| Hypertrophic cardiomyopathy \| 2 HP:0001701 \| Pericarditis \| 2 HP:0011701 \| Ectopic atrial tachycardia \| 1 HP:0003198 \| Myopathic changes \| 1 HP:0001659 \| Aortic insufficiency \| 1 HP:0004308 \| Ventricular arrhythmia \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0001399 \| Liver failure \| 1 HP:0002901 \| Hypocalcemia \| 1 HP:0001909 \| Leukemia \| 1 HP:0006689 \| Bacterial endocarditis \| 1 HP:0002148 \| Hypophosphataemia \| 1 HP:0001733 \| Pancreatic inflammation \| 1 HP:0000855 \| Insulin resistance \| 1 HP:0003201 \| Rhabdomyolysis \| 1 HP:0002138 \| Subarachnoid hemorrhage \| 1 HP:0001406 \| Intrahepatic cholestasis \| 1 HP:0002094 \| Dyspnea \| 1 HP:0002664 \| Neoplasia \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0002239 \| Gastrointestinal hemorrhage \| 1 HP:0011034 \| Amyloid disease \| 1 HP:0002584 \| Intestinal hemorrhage \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0005145 \| Narrowing of coronary artery \| 1 HP:0005110 \| Atrial fibrillation \| 1 HP:0100512 \| Vitamin D deficiency \| 1 HP:0002098 \| Respiratory distress \| 1 HP:0030843 \| Cardiac amyloidosis \| 1 HP:0011852 \| Chylopericardium \| 1 HP:0001279 \| Syncope \| 1 HP:0005180 \| Tricuspid insufficiency \| 1 HP:0003473 \| Fatigable weakness \| 1 HP:0005162 \| Left ventricular impairment \| 1 HP:0001677 \| Coronary artery disease \| 1 HP:0002092 \| Pulmonary artery hypertension \| 1 HP:0001698 \| Pericardial effusions \| 1 HP:0012153 \| Low blood triglyceride levels \| 1 HP:0000716 \| Depression \| 1 HP:0001645 \| Sudden cardiac death \| 1 HP:0012418 \| Low blood oxygen level \| 1 HP:0002878 \| Respiratory failure \| 1 HP:0001945 \| Fever \| 1 HP:0002093 \| progressive respiratory failure \| 1

Disease ID	959
Disease	cardiogenic shock
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
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GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
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Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:20)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0036980	atenolol	D001262	29122-68-7	shock, cardiogenic	MESH:D012770	marker/mechanism	1764831
C0036980	carbachol	D002217	-	shock, cardiogenic	MESH:D012770	marker/mechanism	7110388
C0036980	carbamazepine	D002220	298-46-4	shock, cardiogenic	MESH:D012770	marker/mechanism	20129423
C0036980	carteolol	D002354	51781-06-7	shock, cardiogenic	MESH:D012770	marker/mechanism	1979694
C0036980	chloroquine	D002738	1954/5/7	shock, cardiogenic	MESH:D012770	marker/mechanism	1774400
C0036980	clozapine	D003024	5786-21-0	shock, cardiogenic	MESH:D012770	marker/mechanism	8664211
C0036980	cyclophosphamide	D003520	50-18-0	shock, cardiogenic	MESH:D012770	marker/mechanism	7707444
C0036980	diltiazem	D004110	42399-41-7	shock, cardiogenic	MESH:D012770	marker/mechanism	1979694
C0036980	disopyramide	D004206	3737/9/5	shock, cardiogenic	MESH:D012770	marker/mechanism	7339947
C0036980	fluorouracil	D005472	51-21-8	shock, cardiogenic	MESH:D012770	marker/mechanism	1642435
C0036980	gemcitabine	C056507	103882-84-4	shock, cardiogenic	MESH:D012770	marker/mechanism	10541971
C0036980	glimepiride	C057619	-	shock, cardiogenic	MESH:D012770	marker/mechanism	8911987
C0036980	imipramine	D007099	50-49-7	shock, cardiogenic	MESH:D012770	marker/mechanism	8161395
C0036980	lidocaine	D008012	137-58-6	shock, cardiogenic	MESH:D012770	marker/mechanism	7154501
C0036980	methadone	D008691	76-99-3	shock, cardiogenic	MESH:D012770	marker/mechanism	16997682
C0036980	metoprolol	D008790	37350-58-6	shock, cardiogenic	MESH:D012770	marker/mechanism	18566202
C0036980	milrinone	D020105	78415-72-2	shock, cardiogenic	MESH:D012770	therapeutic	20628043
C0036980	nitroprusside	D009599	15078-28-1	shock, cardiogenic	MESH:D012770	therapeutic	3987325
C0036980	norepinephrine	D009638	51-41-2	shock, cardiogenic	MESH:D012770	therapeutic	21037469
C0036980	propranolol	D011433	525-66-6	shock, cardiogenic	MESH:D012770	marker/mechanism	10460701

FDA approved drug and dosage information(Total Drugs:0)
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FDA labeling changes(Total Drugs:0)
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