PedAM

Pediatric Disease Annotations & Medicines


	calciphylaxis

Disease ID	568
Disease	calciphylaxis
Definition	Condition of induced systemic hypersensitivity in which tissues respond to appropriate challenging agents with a sudden local calcification.
Synonym	calciphylaxes calciphylaxis (disorder) calciphylaxis [disease/finding] calciphylaxis, idiopathic idiopathic calciphylaxis
Orphanet	ORPHANET:280062
DOID	DOID:4734
UMLS	C0006666
MeSH	D002115
SNOMED-CT	SNOMEDCT_US_2016_09_01:237900002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:35) C0022661 \| end-stage renal disease \| 12 C0022658 \| renal disease \| 9 C0020502 \| hyperparathyroidism \| 5 C0035078 \| renal failure \| 5 C0022661 \| chronic renal failure \| 4 C1565489 \| renal insufficiency \| 3 C0024141 \| systemic lupus erythematosus \| 2 C0221002 \| primary hyperparathyroidism \| 2 C0003873 \| rheumatoid arthritis \| 2 C0022661 \| chronic kidney disease \| 2 C0085404 \| poems syndrome \| 2 C0409974 \| lupus erythematosus \| 2 C0155626 \| acute mi \| 1 C0020503 \| secondary hyperparathyroidism \| 1 C0022658 \| kidney disease \| 1 C0023890 \| cirrhosis \| 1 C0398623 \| hypercoagulability \| 1 C0024143 \| lupus nephritis \| 1 C0878486 \| arteriolosclerosis \| 1 C0403447 \| chronic renal insufficiency \| 1 C0027697 \| nephritis \| 1 C0023895 \| liver disease \| 1 C0262587 \| parathyroid adenomas \| 1 C0151468 \| thyroid adenoma \| 1 C0023891 \| alcoholic cirrhosis \| 1 C0242666 \| protein s deficiency \| 1 C0022660 \| acute renal failure \| 1 C0042384 \| vasculitis \| 1 C0262587 \| parathyroid adenoma \| 1 C0023890 \| liver cirrhosis \| 1 C0023891 \| alcoholic liver cirrhosis \| 1 C0003864 \| arthritis \| 1 C0020626 \| hypoparathyroidism \| 1 C0026266 \| mitral regurgitation \| 1 C0022661 \| end stage renal disease \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:32) 368 \| ABCC6 \| DISEASES 1311 \| COMP \| DISEASES 4256 \| MGP \| DISEASES 5624 \| PROC \| DISEASES 8074 \| FGF23 \| DISEASES 10343 \| PKDREJ \| DISEASES 4907 \| NT5E \| DISEASES 9172 \| MYOM2 \| DISEASES 11043 \| MID2 \| DISEASES 4924 \| NUCB1 \| DISEASES 5741 \| PTH \| DISEASES 6781 \| STC1 \| DISEASES 213 \| ALB \| DISEASES 4982 \| TNFRSF11B \| DISEASES 50964 \| SOST \| DISEASES 5340 \| PLG \| DISEASES 5745 \| PTH1R \| DISEASES 796 \| CALCA \| DISEASES 2335 \| FN1 \| DISEASES 5167 \| ENPP1 \| DISEASES 4514 \| MT-CO3 \| DISEASES 860 \| RUNX2 \| DISEASES 650 \| BMP2 \| DISEASES 114899 \| C1QTNF3 \| DISEASES 2591 \| GALNT3 \| DISEASES 79001 \| VKORC1 \| DISEASES 6696 \| SPP1 \| DISEASES 197 \| AHSG \| DISEASES 9278 \| ZBTB22 \| DISEASES 846 \| CASR \| DISEASES 7421 \| VDR \| DISEASES 8972 \| MGAM \| DISEASES
Locus	(Waiting for update.)

Disease ID	568
Disease	calciphylaxis
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:12) HP:0002905 \| Hyperphosphatemia HP:0100806 \| Sepsis HP:0003207 \| Arterial calcification HP:0001939 \| Abnormality of metabolism/homeostasis HP:0000965 \| Cutis marmorata HP:0011986 \| Ectopic ossification HP:0100658 \| Cellulitis HP:0011122 \| Abnormality of skin physiology HP:0000867 \| Secondary hyperparathyroidism HP:0100758 \| Gangrene HP:0200042 \| Skin ulcer HP:0003774 \| Stage 5 chronic kidney disease
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:25) HP:0003774 \| End-stage renal failure \| 17 HP:0000083 \| Renal insufficiency \| 8 HP:0000843 \| Hyperparathyroidism \| 5 HP:0001370 \| Rheumatoid arthritis \| 2 HP:0002725 \| Systemic lupus erythematosus \| 2 HP:0012622 \| Chronic kidney disease \| 2 HP:0100758 \| Gangrene \| 2 HP:0001919 \| Acute renal failure \| 2 HP:0008200 \| Primary hyperparathyroidism \| 2 HP:0000829 \| Hypoparathyroidism \| 1 HP:0004934 \| Vascular calcification \| 1 HP:0002901 \| Hypocalcemia \| 1 HP:0000867 \| Secondary hyperparathyroidism \| 1 HP:0001394 \| Hepatic cirrhosis \| 1 HP:0001653 \| Mitral valve insufficiency \| 1 HP:0004382 \| Mitral valve calcification \| 1 HP:0000854 \| Thyroid adenoma \| 1 HP:0011770 \| Tertiary hyperparathyroidism \| 1 HP:0001369 \| Arthritis \| 1 HP:0002897 \| Parathyroid adenoma \| 1 HP:0012531 \| Pain \| 1 HP:0100724 \| Hypercoagulability \| 1 HP:0002633 \| Vasculitis \| 1 HP:0002664 \| Neoplasia \| 1 HP:0000123 \| Nephritis \| 1

Disease ID	568
Disease	calciphylaxis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:11) C2598155 \| pain C1611707 \| penile necrosis C1411989 \| angiomatosis C1402315 \| vascular lesions C0948089 \| acute coronary syndrome C0459830 \| foot gangrene C0451641 \| urolithiasis C0037284 \| skin lesions C0030326 \| panniculitis C0022660 \| acute renal failure C0022116 \| ischemia
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:5) C0037284 \| skin lesions \| 2 C1611707 \| penile necrosis \| 2 C0022660 \| acute renal failure \| 1 C0030193 \| pain \| 1 C0002992 \| angiomatosis \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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