PedAM
Pediatric Disease Annotations & Medicines
| bile duct carcinoma | ||||
| Disease ID | 973 |
|---|---|
| Disease | bile duct carcinoma |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:2) |
| Disease ID | 973 |
|---|---|
| Disease | bile duct carcinoma |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:5) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:7) | |||||||||||||
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| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs1003723 | 18296645 | 3949 | LDLR | umls:C0740277 | BeFree | Male and female carriers of the T allele of LDLR IVS9-30C>T (rs1003723) had a 1.5-fold risk of bile duct cancer. | 0.000271442 | 2008 | LDLR;MIR6886 | 19 | 11113505 | C | T |
| rs1126579 | 18676870 | 3579 | CXCR2 | umls:C0740277 | BeFree | Of the 10 genes with multiple SNPs from which we inferred haplotypes, only one IL8RB haplotype, consisting of 3 SNPs (rs2230054, rs1126579, and rs1126580), was associated with the risk of bile duct cancer (P = 0.003) and biliary stones (P = 0.02), relative to the most frequent haplotype. | 0.000271442 | 2008 | CXCR2 | 2 | 218136011 | T | C |
| rs1126580 | 18676870 | 3579 | CXCR2 | umls:C0740277 | BeFree | Of the 10 genes with multiple SNPs from which we inferred haplotypes, only one IL8RB haplotype, consisting of 3 SNPs (rs2230054, rs1126579, and rs1126580), was associated with the risk of bile duct cancer (P = 0.003) and biliary stones (P = 0.02), relative to the most frequent haplotype. | 0.000271442 | 2008 | CXCR2 | 2 | 218136243 | G | A |
| rs11887534 | 21062971 | 64241 | ABCG8 | umls:C0740277 | BeFree | Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype. | 0.000271442 | 2011 | ABCG5;ABCG8 | 2 | 43839108 | G | A,C |
| rs2230054 | 18676870 | 3579 | CXCR2 | umls:C0740277 | BeFree | Of the 10 genes with multiple SNPs from which we inferred haplotypes, only one IL8RB haplotype, consisting of 3 SNPs (rs2230054, rs1126579, and rs1126580), was associated with the risk of bile duct cancer (P = 0.003) and biliary stones (P = 0.02), relative to the most frequent haplotype. | 0.000271442 | 2008 | CXCR2 | 2 | 218135587 | C | T |
| rs4986938 | 20172949 | 6817 | SULT1A1 | umls:C0740277 | BeFree | Also, the ESR2 rs4986938 (38 bp 3' of STP) GG genotype was associated with a higher risk of bile duct cancer (OR = 3.3, 95% CI 1.3-8.7) compared with the AA genotype, although this estimate was based on a small number of subjects. | 0.000271442 | 2010 | ESR2 | 14 | 64233098 | C | T |
| rs4986938 | 20172949 | 2100 | ESR2 | umls:C0740277 | BeFree | Also, the ESR2 rs4986938 (38 bp 3' of STP) GG genotype was associated with a higher risk of bile duct cancer (OR = 3.3, 95% CI 1.3-8.7) compared with the AA genotype, although this estimate was based on a small number of subjects. | 0.000271442 | 2010 | ESR2 | 14 | 64233098 | C | T |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |