PedAM
Pediatric Disease Annotations & Medicines
| bacterial vaginosis | ||||
| Disease ID | 1243 |
|---|---|
| Disease | bacterial vaginosis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0001622 | Premature delivery | 4 HP:0000789 | Infertility | 2 HP:0100512 | Vitamin D deficiency | 2 HP:0002027 | Abdominal pain | 1 HP:0012531 | Pain | 1 HP:0200043 | Verrucae | 1 HP:0001788 | Premature rupture of membranes | 1 HP:0030160 | Uterine cervicitis | 1 HP:0001548 | Overgrowth | 1 |
| Disease ID | 1243 |
|---|---|
| Disease | bacterial vaginosis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:3) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:4) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs10759932 | 18928988 | 134083 | OR2Y1 | umls:C0085166 | BeFree | After adjustment for race, smoking, and bacterial vaginosis, carriage of these alleles was associated with chorionic plate inflammation (maternal rs1554973: odds ratio [OR] 5.2, 95% confidence interval, 3.2-6.4, P = .006; fetal rs10759932: OR 4.95, 95% confidence interval, 3.0-5.6, P = .005). | 0.000271442 | 2008 | TLR4 | 9 | 117702866 | T | C |
| rs1554973 | 18928988 | 134083 | OR2Y1 | umls:C0085166 | BeFree | After adjustment for race, smoking, and bacterial vaginosis, carriage of these alleles was associated with chorionic plate inflammation (maternal rs1554973: odds ratio [OR] 5.2, 95% confidence interval, 3.2-6.4, P = .006; fetal rs10759932: OR 4.95, 95% confidence interval, 3.0-5.6, P = .005). | 0.000271442 | 2008 | NA | 9 | 117718534 | T | C |
| rs187084 | 23021866 | 7099 | TLR4 | umls:C0085166 | BeFree | Two SNPs were associated with BV as diagnosed by the Nugent score and the combined criteria: a minor allele G of rs4986790 (frequency=0.07), which encodes a His to Tyr substitution in TLR4 (HR=1.47, 95% CI 1.15-1.87) and rs187084 (frequency=0.24) on TLR9. | 0.006091273 | 2012 | TLR9 | 3 | 52227015 | A | G |
| rs4986790 | 23021866 | 7099 | TLR4 | umls:C0085166 | BeFree | Two SNPs were associated with BV as diagnosed by the Nugent score and the combined criteria: a minor allele G of rs4986790 (frequency=0.07), which encodes a His to Tyr substitution in TLR4 (HR=1.47, 95% CI 1.15-1.87) and rs187084 (frequency=0.24) on TLR9. | 0.006091273 | 2012 | TLR4 | 9 | 117713024 | A | G |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |