PedAM

Pediatric Disease Annotations & Medicines


	avian influenza

Disease ID	1475
Disease	avian influenza
Definition	Birds, just like people, get the flu. Bird flu viruses infect birds, including chickens, other poultry, and wild birds such as ducks. Most bird flu viruses can only infect other birds. However, bird flu can pose health risks to people. The first case of a bird flu virus infecting a person directly, H5N1, was in Hong Kong in 1997. Since then, the bird flu virus has spread to birds in countries in Asia, Africa, the Middle East, and Europe. Human infection is still very rare, but the virus that causes the infection in birds might change, or mutate, to more easily infect humans. This could lead to a pandemic, a worldwide outbreak of the illness. During an outbreak of bird flu, people who have contact with infected birds can become sick. It may also be possible to catch bird flu by eating poultry or eggs that are not well cooked or through contact with a person who has it. Bird flu can make people very sick or even cause death. Antiviral medicines may make the illness less severe, and may help prevent the flu in people who were exposed to it. There is currently no vaccine.
Synonym	avian flu avian flu virus avian influenza (disorder) avian influenzas bird flu bird flu virus flu, avian fowl plague h5n1 h7n9 influenza in bird influenza in birds influenza in birds [disease/finding] influenza, avian influenzas, avian plague, fowl
DOID	DOID:4492
UMLS	C0016627
MeSH	D005585
SNOMED-CT	SNOMEDCT_US_2016_09_01:55604004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:7) C0021400 \| influenza \| 5 C0032285 \| pneumonia \| 3 C1704437 \| respiratory distress syndrome \| 3 C0035222 \| acute respiratory distress syndrome \| 2 C0021400 \| human influenza \| 1 C0003467 \| anxiety \| 1 C0024312 \| lymphocytopenia \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) MX1 \| 4599 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:221) 8935 \| SKAP2 \| DISEASES 1357 \| CPA1 \| DISEASES 51564 \| HDAC7 \| DISEASES 4335 \| MNT \| DISEASES 11274 \| USP18 \| DISEASES 5753 \| PTK6 \| DISEASES 30844 \| EHD4 \| DISEASES 2765 \| GML \| DISEASES 54623 \| PAF1 \| DISEASES 973 \| CD79A \| DISEASES 3036 \| HAS1 \| DISEASES 6528 \| SLC5A5 \| DISEASES 2077 \| ERF \| DISEASES 7461 \| CLIP2 \| DISEASES 6348 \| CCL3 \| DISEASES 8688 \| KRT37 \| DISEASES 1655 \| DDX5 \| DISEASES 6347 \| CCL2 \| DISEASES 3558 \| IL2 \| DISEASES 6484 \| ST3GAL4 \| DISEASES 969 \| CD69 \| DISEASES 3458 \| IFNG \| DISEASES 50856 \| CLEC4A \| DISEASES 55856 \| ACOT13 \| DISEASES 3565 \| IL4 \| DISEASES 4759 \| NEU2 \| DISEASES 3218 \| HOXB8 \| DISEASES 1843 \| DUSP1 \| DISEASES 56829 \| ZC3HAV1 \| DISEASES 7374 \| UNG \| DISEASES 1446 \| CSN1S1 \| DISEASES 5300 \| PIN1 \| DISEASES 6351 \| CCL4 \| DISEASES 79132 \| DHX58 \| DISEASES 3854 \| KRT6B \| DISEASES 6289 \| SAA2 \| DISEASES 8638 \| OASL \| DISEASES 3569 \| IL6 \| DISEASES 6426 \| SRSF1 \| DISEASES 7097 \| TLR2 \| DISEASES 10068 \| IL18BP \| DISEASES 10017 \| BCL2L10 \| DISEASES 4659 \| PPP1R12A \| DISEASES 51637 \| C14orf166 \| DISEASES 10558 \| SPTLC1 \| DISEASES 11043 \| MID2 \| DISEASES 6487 \| ST3GAL3 \| DISEASES 5605 \| MAP2K2 \| DISEASES 3553 \| IL1B \| DISEASES 64135 \| IFIH1 \| DISEASES 9828 \| ARHGEF17 \| DISEASES 7301 \| TYRO3 \| DISEASES 25885 \| POLR1A \| DISEASES 941 \| CD80 \| DISEASES 25759 \| SHC2 \| DISEASES 3371 \| TNC \| DISEASES 6895 \| TARBP2 \| DISEASES 5045 \| FURIN \| DISEASES 3858 \| KRT10 \| DISEASES 3454 \| IFNAR1 \| DISEASES 90226 \| UCN2 \| DISEASES 100996939 \| PYURF \| DISEASES 55435 \| AP1AR \| DISEASES 83551 \| TAAR8 \| DISEASES 3439 \| IFNA1 \| DISEASES 3606 \| IL18 \| DISEASES 9407 \| TMPRSS11D \| DISEASES 6352 \| CCL5 \| DISEASES 162417 \| NAGS \| DISEASES 79885 \| HDAC11 \| DISEASES 5648 \| MASP1 \| DISEASES 128 \| ADH5 \| DISEASES 7098 \| TLR3 \| DISEASES 382 \| ARF6 \| DISEASES 3429 \| IFI27 \| DISEASES 6236 \| RRAD \| DISEASES 10982 \| MAPRE2 \| DISEASES 124872 \| B4GALNT2 \| DISEASES 1398 \| CRK \| DISEASES 51435 \| SCARA3 \| DISEASES 719 \| C3AR1 \| DISEASES 116844 \| LRG1 \| DISEASES 253959 \| RALGAPA1 \| DISEASES 6249 \| CLIP1 \| DISEASES 260425 \| MAGI3 \| DISEASES 54538 \| ROBO4 \| DISEASES 5046 \| PCSK6 \| DISEASES 3627 \| CXCL10 \| DISEASES 3669 \| ISG20 \| DISEASES 6373 \| CXCL11 \| DISEASES 3913 \| LAMB2 \| DISEASES 57521 \| RPTOR \| DISEASES 6363 \| CCL19 \| DISEASES 81793 \| TLR10 \| DISEASES 3661 \| IRF3 \| DISEASES 64236 \| PDLIM2 \| DISEASES 653499 \| LGALS7B \| DISEASES 6773 \| STAT2 \| DISEASES 8560 \| DEGS1 \| DISEASES 475 \| ATOX1 \| DISEASES 53347 \| UBASH3A \| DISEASES 196500 \| PIANP \| DISEASES 23621 \| BACE1 \| DISEASES 54984 \| PINX1 \| DISEASES 2193 \| FARSA \| DISEASES 10331 \| B3GNT3 \| DISEASES 23212 \| RRS1 \| DISEASES 7284 \| TUFM \| DISEASES 10194 \| TSHZ1 \| DISEASES 7706 \| TRIM25 \| DISEASES 7329 \| UBE2I \| DISEASES 4670 \| HNRNPM \| DISEASES 9159 \| PCSK7 \| DISEASES 84282 \| RNF135 \| DISEASES 3665 \| IRF7 \| DISEASES 9021 \| SOCS3 \| DISEASES 8519 \| IFITM1 \| DISEASES 6938 \| TCF12 \| DISEASES 9146 \| HGS \| DISEASES 5104 \| SERPINA5 \| DISEASES 4600 \| MX2 \| DISEASES 10519 \| CIB1 \| DISEASES 114548 \| NLRP3 \| DISEASES 3185 \| HNRNPF \| DISEASES 7100 \| TLR5 \| DISEASES 126364 \| LRRC25 \| DISEASES 26088 \| GGA1 \| DISEASES 23394 \| ADNP \| DISEASES 4077 \| NBR1 \| DISEASES 3605 \| IL17A \| DISEASES 84706 \| GPT2 \| DISEASES 347148 \| QRFP \| DISEASES 9863 \| MAGI2 \| DISEASES 1399 \| CRKL \| DISEASES 54898 \| ELOVL2 \| DISEASES 133584 \| EGFLAM \| DISEASES 5979 \| RET \| DISEASES 5284 \| PIGR \| DISEASES 5625 \| PRODH \| DISEASES 51530 \| ZC3HC1 \| DISEASES 8356 \| HIST1H3J \| DISEASES 4192 \| MDK \| DISEASES 8353 \| HIST1H3E \| DISEASES 6772 \| STAT1 \| DISEASES 22920 \| KIFAP3 \| DISEASES 51599 \| LSR \| DISEASES 54739 \| XAF1 \| DISEASES 4283 \| CXCL9 \| DISEASES 5664 \| PSEN2 \| DISEASES 343035 \| RD3 \| DISEASES 89796 \| NAV1 \| DISEASES 140609 \| NEK7 \| DISEASES 1660 \| DHX9 \| DISEASES 6375 \| XCL1 \| DISEASES 26227 \| PHGDH \| DISEASES 1117 \| CHI3L2 \| DISEASES 2832 \| NPBWR2 \| DISEASES 2633 \| GBP1 \| DISEASES 959 \| CD40LG \| DISEASES 24138 \| IFIT5 \| DISEASES 6130 \| RPL7A \| DISEASES 6441 \| SFTPD \| DISEASES 22845 \| DOLK \| DISEASES 127544 \| RNF19B \| DISEASES 6428 \| SRSF3 \| DISEASES 4736 \| RPL10A \| DISEASES 1674 \| DES \| DISEASES 3108 \| HLA-DMA \| DISEASES 58496 \| LY6G5B \| DISEASES 1460 \| CSNK2B \| DISEASES 5355 \| PLP2 \| DISEASES 6461 \| SHB \| DISEASES 54880 \| BCOR \| DISEASES 3963 \| LGALS7 \| DISEASES 23586 \| DDX58 \| DISEASES 3456 \| IFNB1 \| DISEASES 51284 \| TLR7 \| DISEASES 91543 \| RSAD2 \| DISEASES 387733 \| IFITM5 \| DISEASES 348801 \| LNP1 \| DISEASES 11235 \| PDCD10 \| DISEASES 3886 \| KRT35 \| DISEASES 28964 \| GIT1 \| DISEASES 130 \| ADH6 \| DISEASES 3895 \| KTN1 \| DISEASES 89797 \| NAV2 \| DISEASES 7919 \| DDX39B \| DISEASES 10521 \| DDX17 \| DISEASES 8570 \| KHSRP \| DISEASES 7113 \| TMPRSS2 \| DISEASES 4599 \| MX1 \| DISEASES 10410 \| IFITM3 \| DISEASES 10581 \| IFITM2 \| DISEASES 23515 \| MORC3 \| DISEASES 10747 \| MASP2 \| DISEASES 55714 \| TENM3 \| DISEASES 23066 \| CAND2 \| DISEASES 4776 \| NFATC4 \| DISEASES 7124 \| TNF \| DISEASES 6635 \| SNRPE \| DISEASES 4615 \| MYD88 \| DISEASES 57506 \| MAVS \| DISEASES 3609 \| ILF3 \| DISEASES 388372 \| CCL4L1 \| DISEASES 3451 \| IFNA17 \| DISEASES 56649 \| TMPRSS4 \| DISEASES 79012 \| CAMKV \| DISEASES 30816 \| ERVW-1 \| DISEASES 10189 \| ALYREF \| DISEASES 51428 \| DDX41 \| DISEASES 100289462 \| DEFB4B \| DISEASES 84000 \| TMPRSS13 \| DISEASES 8352 \| HIST1H3C \| DISEASES 57128 \| LYRM4 \| DISEASES 89795 \| NAV3 \| DISEASES 5125 \| PCSK5 \| DISEASES 11153 \| FICD \| DISEASES 4666 \| NACA \| DISEASES 4065 \| LY75 \| DISEASES 11201 \| POLI \| DISEASES 4574 \| MT-TS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1475
Disease	avian influenza
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:8) HP:0002098 \| Respiratory distress \| 3 HP:0002090 \| Pneumonia \| 3 HP:0011947 \| Respiratory infection \| 2 HP:0001945 \| Fever \| 2 HP:0030005 \| Capillary leak \| 1 HP:0000739 \| Anxiety \| 1 HP:0001888 \| Lymphocytopenia \| 1 HP:0002719 \| infections, recurrent \| 1

Disease ID	1475
Disease	avian influenza
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:3) C0009450 \| infection \| 174 C0021311 \| infections \| 90 C0032285 \| pneumonia \| 3

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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