PedAM

Pediatric Disease Annotations & Medicines


	atrial fibrillation

Disease ID	380
Disease	atrial fibrillation
Definition	Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Synonym	af - atrial fibrillation afib atrial fibrillation (af) atrial fibrillation (disorder) atrial fibrillation [disease/finding] atrial fibrillations auricular fibrillation auricular fibrillations fibrillation - atrial fibrillation atrial fibrillation, atrial fibrillation, auricular fibrillations, atrial fibrillations, auricular
DOID	DOID:0060224
UMLS	C0004238
MeSH	D001281
SNOMED-CT	SNOMEDCT_US_2016_09_01:49436004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:202) C0018801 \| heart failure \| 135 C0040053 \| thrombus \| 61 C0018799 \| heart disease \| 53 C0027051 \| myocardial infarct \| 47 C0027051 \| myocardial infarction \| 47 C0020538 \| hypertension \| 35 C0155626 \| acute myocardial infarction \| 32 C0011847 \| diabetes \| 27 C0007194 \| hypertrophic cardiomyopathy \| 25 C0010068 \| coronary artery disease \| 21 C0878544 \| cardiomyopathy \| 19 C0020550 \| hyperthyroidism \| 16 C0007787 \| transient ischemic attack \| 16 C0022661 \| chronic kidney disease \| 15 C0087086 \| thrombi \| 15 C0011849 \| diabetes mellitus \| 14 C0022658 \| kidney disease \| 14 C0026265 \| mitral valve disease \| 14 C0018802 \| congestive heart failure \| 14 C0007785 \| cerebral infarct \| 13 C0026269 \| mitral stenosis \| 13 C0011860 \| type 2 diabetes \| 12 C0007785 \| cerebral infarction \| 11 C0037315 \| sleep apnea \| 11 C0022661 \| end-stage renal disease \| 11 C0042373 \| vascular disease \| 11 C0022658 \| renal disease \| 11 C0040053 \| thrombosis \| 11 C0035439 \| rheumatic heart disease \| 10 C0520679 \| obstructive sleep apnea \| 10 C0011570 \| depression \| 10 C0018824 \| valvular heart disease \| 9 C0037052 \| sick sinus syndrome \| 9 C0043202 \| wolff-parkinson-white syndrome \| 8 C0028754 \| obesity \| 8 C0022116 \| ischemia \| 8 C0006384 \| bundle branch block \| 7 C0948265 \| metabolic syndrome \| 7 C0007222 \| cardiovascular disease \| 7 C0003507 \| aortic stenosis \| 7 C0264766 \| rheumatic mitral stenosis \| 7 C0007787 \| transient ischaemic attack \| 6 C0745140 \| hyperthyroid \| 6 C0026266 \| mitral regurgitation \| 6 C0007785 \| cerebral ischemia \| 6 C0600260 \| obstructive pulmonary disease \| 5 C0020676 \| hypothyroidism \| 5 C0010068 \| coronary heart disease \| 5 C0024115 \| pulmonary disease \| 5 C0033860 \| psoriasis \| 5 C0024117 \| chronic obstructive pulmonary disease \| 4 C0085580 \| essential hypertension \| 4 C0264716 \| chronic heart failure \| 4 C0020542 \| pulmonary hypertension \| 4 C0018213 \| graves' disease \| 4 C0497327 \| dementia \| 4 C0003873 \| rheumatoid arthritis \| 4 C1561644 \| chronic kidney disease (ckd) \| 4 C0037315 \| sleep apnoea \| 3 C0007193 \| dilated cardiomyopathy \| 3 C0037315 \| sleep-disordered breathing \| 3 C0007787 \| transient ischemic attack (tia) \| 3 C0022661 \| chronic renal failure \| 3 C0031039 \| pericardial effusion \| 3 C0035078 \| renal failure \| 3 C0007785 \| cerebral infarctions \| 3 C0014544 \| epileptic seizure \| 3 C0017168 \| oesophageal reflux \| 3 C0017168 \| gastroesophageal reflux disease \| 3 C0014544 \| epileptic seizures \| 3 C0017168 \| esophageal reflux \| 3 C0003467 \| anxiety \| 3 C0004153 \| atherosclerosis \| 3 C0034065 \| pulmonary embolism \| 3 C0018799 \| heart diseases \| 3 C0242350 \| erectile dysfunction \| 3 C0011860 \| type 2 diabetes mellitus \| 3 C0017168 \| gastroesophageal reflux \| 3 C0027051 \| myocardial infarction (mi) \| 3 C1135191 \| systolic heart failure \| 3 C1142166 \| brugada syndrome \| 3 C0004245 \| atrioventricular block \| 3 C0017168 \| esophageal reflux disease \| 3 C0520679 \| obstructive sleep apnoea \| 3 C0040127 \| thyroid storm \| 2 C0010068 \| coronary disease \| 2 C0152021 \| congenital heart disease \| 2 C0003864 \| arthritis \| 2 C0018799 \| cardiac disorders \| 2 C0002726 \| amyloidosis \| 2 C0019069 \| hemophilia \| 2 C0033687 \| proteinuria \| 2 C0003507 \| aortic valve stenosis \| 2 C0014118 \| endocarditis \| 2 C0026265 \| mitral valvular disease \| 2 C0152105 \| hypertensive heart disease \| 2 C0022116 \| ischaemia \| 2 C0026266 \| mitral valve regurgitation \| 2 C0018799 \| cardiac disease \| 2 C0024115 \| lung disease \| 2 C0007102 \| colon cancer \| 2 C0007570 \| coeliac disease \| 1 C0242379 \| lung cancer \| 1 C0018824 \| heart valve disease \| 1 C0018991 \| hemiplegia \| 1 C0034063 \| lung edema \| 1 C0029456 \| osteoporosis \| 1 C1332850 \| primary cardiac lymphoma \| 1 C0020456 \| hyperglycaemia \| 1 C0026848 \| myopathy \| 1 C0392077 \| cardiac sarcoidosis \| 1 C0024299 \| lymphoma \| 1 C0040137 \| thyroid nodule \| 1 C0398623 \| hypercoagulability \| 1 C0011269 \| vascular dementia \| 1 C0677607 \| hashimoto's thyroiditis \| 1 C0043202 \| wolff parkinson white syndrome \| 1 C0036202 \| sarcoidosis \| 1 C0014121 \| bacterial endocarditis \| 1 C0020538 \| high blood pressure \| 1 C0007113 \| rectal cancer \| 1 C0007570 \| celiac disease \| 1 C0040034 \| thrombocytopenia \| 1 C0162429 \| undernourished \| 1 C0520680 \| central sleep apnea \| 1 C0002395 \| alzheimer's disease \| 1 C0007785 \| cerebral infarcts \| 1 C0009319 \| colitis \| 1 C0032285 \| pneumonia \| 1 C0007787 \| transient ischaemic attacks \| 1 C0268407 \| cardiac amyloidosis \| 1 C0011860 \| diabetes mellitus type 2 \| 1 C0009402 \| colorectal cancer \| 1 C0009241 \| cognitive disorders \| 1 C0022660 \| acute renal failure \| 1 C0852949 \| arterial disease \| 1 C0751955 \| brain infarction \| 1 C0003500 \| subvalvular aortic stenosis \| 1 C0029463 \| osteosarcoma \| 1 C0043202 \| wpw syndrome \| 1 C0039538 \| teratoma \| 1 C0007930 \| chagas cardiomyopathy \| 1 C0020676 \| hypothyroid \| 1 C0151744 \| myocardial ischemia \| 1 C0030920 \| peptic ulcer \| 1 C0035258 \| restless legs \| 1 C1135196 \| diastolic heart failure \| 1 C0264765 \| mitral valve diseases \| 1 C0019069 \| haemophilia \| 1 C0035258 \| restless legs syndrome \| 1 C0022661 \| end-stage kidney disease \| 1 C0007196 \| restrictive cardiomyopathy \| 1 C0030305 \| pancreatitis \| 1 C0917713 \| becker muscular dystrophy \| 1 C0007177 \| cardiac tamponade \| 1 C0003537 \| aphasia \| 1 C0020456 \| hyperglycemia \| 1 C0026850 \| muscular dystrophy \| 1 C0020538 \| hypertensive disease \| 1 C0282193 \| iron overload \| 1 C0342388 \| adrenocorticotropic hormone deficiency \| 1 C0040137 \| thyroid nodules \| 1 C0751955 \| brain infarct \| 1 C0151744 \| ischaemic heart disease \| 1 C0026266 \| mitral insufficiency \| 1 C0014544 \| epilepsy \| 1 C0040156 \| thyrotoxicosis \| 1 C0022661 \| end stage renal disease \| 1 C0398623 \| hypercoagulable state \| 1 C0003125 \| anorexia nervosa \| 1 C0019158 \| hepatitis \| 1 C0023364 \| leptospirosis \| 1 C0085615 \| right bundle branch block \| 1 C0024115 \| lung diseases \| 1 C0003507 \| valvular aortic stenosis \| 1 C0001339 \| acute pancreatitis \| 1 C0009324 \| ulcerative colitis \| 1 C0040961 \| tricuspid regurgitation \| 1 C0029408 \| osteoarthritis \| 1 C0035309 \| retinal disease \| 1 C0004943 \| behcet's disease \| 1 C0011860 \| non-insulin dependent diabetes \| 1 C1704436 \| peripheral arterial disease \| 1 C0016522 \| patent foramen ovale \| 1 C0043202 \| wolf-parkinson-white syndrome \| 1 C0037998 \| splenic infarction \| 1 C0018824 \| heart valve diseases \| 1 C0031046 \| pericarditis \| 1 C0019204 \| hepatocellular carcinoma \| 1 C0011854 \| insulin dependent diabetes \| 1 C0023976 \| long qt syndrome \| 1 C0398623 \| hypercoagulability state \| 1 C0342388 \| acth deficiency \| 1 C0014038 \| encephalitis \| 1 C1565489 \| renal insufficiency \| 1 C0023895 \| hepatopathy \| 1 C0040128 \| thyroid disease \| 1 C0878544 \| cardiomyopathies \| 1 C0035309 \| retinal diseases \| 1 C0003504 \| aortic insufficiency \| 1 C1631597 \| catecholaminergic polymorphic ventricular tachycardia \| 1 C0002895 \| sickle cell disease \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:37) NKX2-5 \| 1482 \| CTD_human NOS3 \| 4846 \| CTD_human EDN1 \| 1906 \| CTD_human DES \| 1674 \| CTD_human KCNN3 \| 3782 \| CTD_human;GWASCAT SCN4B \| 6330 \| UniProtKB-KW ACE \| 1636 \| CTD_human SCN1B \| 6324 \| UniProtKB-KW NPPB \| 4879 \| CTD_human SELE \| 6401 \| CTD_human MTHFR \| 4524 \| GWASCAT HCN4 \| 10021 \| CTD_human;GWASCAT ABCC9 \| 10060 \| UniProtKB-KW C9orf3 \| 84909 \| CTD_human;GWASCAT SYNE2 \| 23224 \| CTD_human;GWASCAT NPPA \| 4878 \| UniProtKB-KW SCN3B \| 55800 \| UniProtKB-KW KCNE2 \| 9992 \| CTD_human;UniProtKB-KW;GHR GJA5 \| 2702 \| UniProtKB-KW ESR2 \| 2100 \| GWASCAT SCN5A \| 6331 \| CLINVAR;CTD_human;UniProtKB-KW VWF \| 7450 \| CTD_human SOX5 \| 6660 \| CTD_human SCN10A \| 6336 \| CTD_human KCNA5 \| 3741 \| CTD_human;UniProtKB-KW PRRX1 \| 5396 \| CTD_human CAV1 \| 857 \| CTD_human;GWASCAT CAV2 \| 858 \| CTD_human SCN2B \| 6327 \| UniProtKB-KW WNT8A \| 7478 \| CTD_human;GWASCAT KCNQ1 \| 3784 \| UniProtKB-KW;GHR TBX5 \| 6910 \| UniProtKB-KW ZFHX3 \| 463 \| CTD_human;GWASCAT KCNJ2 \| 3759 \| CLINVAR;UniProtKB-KW;GHR NUP155 \| 9631 \| UniProtKB-KW MYL4 \| 4635 \| UniProtKB-KW HTR4 \| 3360 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:49) 1636 \| ACE \| infer 153 \| ADRB1 \| infer 183 \| AGT \| infer 185 \| AGTR1 \| infer 54796 \| BNC2 \| infer 4345 \| CD200 \| infer 1071 \| CETP \| infer 53942 \| CNTN5 \| infer 1401 \| CRP \| infer 1585 \| CYP11B2 \| infer 1559 \| CYP2C9 \| infer 1565 \| CYP2D6 \| infer 4189 \| DNAJB9 \| infer 1848 \| DUSP6 \| infer 2099 \| ESR1 \| infer 2162 \| F13A1 \| infer 2702 \| GJA5 \| infer 2784 \| GNB3 \| infer 83872 \| HMCN1 \| infer 3586 \| IL10 \| infer 3741 \| KCNA5 \| infer 3753 \| KCNE1 \| infer 23704 \| KCNE4 \| infer 3757 \| KCNH2 \| infer 3762 \| KCNJ5 \| infer 3782 \| KCNN3 \| infer 3784 \| KCNQ1 \| infer 220416 \| LRRC63 \| infer 50488 \| MINK1 \| infer 4313 \| MMP2 \| infer 4524 \| MTHFR \| infer 4846 \| NOS3 \| infer 4878 \| NPPA \| infer 5099 \| PCDH7 \| infer 5308 \| PITX2 \| infer 54715 \| RBFOX1 \| infer 100271279 \| RPL13AP15 \| infer 728010 \| RPL35P3 \| infer 6176 \| RPLP1 \| infer 55800 \| SCN3B \| infer 6331 \| SCN5A \| infer 9723 \| SEMA3E \| infer 92369 \| SPSB4 \| infer 55959 \| SULF2 \| infer 6938 \| TCF12 \| infer 8615 \| USO1 \| infer 139538 \| VENTXP1 \| infer 79001 \| VKORC1 \| infer 463 \| ZFHX3 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:484) 5898 \| RALA \| DISEASES 84245 \| MRI1 \| DISEASES 5318 \| PKP2 \| DISEASES 3784 \| KCNQ1 \| DISEASES 1071 \| CETP \| DISEASES 4282 \| MIF \| DISEASES 328 \| APEX1 \| DISEASES 10278 \| EFS \| DISEASES 10857 \| PGRMC1 \| DISEASES 2158 \| F9 \| DISEASES 7076 \| TIMP1 \| DISEASES 479 \| ATP12A \| DISEASES 4313 \| MMP2 \| DISEASES 1666 \| DECR1 \| DISEASES 5327 \| PLAT \| DISEASES 56729 \| RETN \| DISEASES 8529 \| CYP4F2 \| DISEASES 2091 \| FBL \| DISEASES 7040 \| TGFB1 \| DISEASES 5054 \| SERPINE1 \| DISEASES 58498 \| MYL7 \| DISEASES 4353 \| MPO \| DISEASES 6347 \| CCL2 \| DISEASES 6783 \| SULT1E1 \| DISEASES 3558 \| IL2 \| DISEASES 1594 \| CYP27B1 \| DISEASES 4633 \| MYL2 \| DISEASES 4256 \| MGP \| DISEASES 2597 \| GAPDH \| DISEASES 9896 \| FIG4 \| DISEASES 9450 \| LY86 \| DISEASES 4015 \| LOX \| DISEASES 9631 \| NUP155 \| DISEASES 7035 \| TFPI \| DISEASES 374291 \| NDUFS7 \| DISEASES 2677 \| GGCX \| DISEASES 3336 \| HSPE1 \| DISEASES 5510 \| PPP1R7 \| DISEASES 1185 \| CLCN6 \| DISEASES 7276 \| TTR \| DISEASES 8074 \| FGF23 \| DISEASES 54812 \| AFTPH \| DISEASES 5396 \| PRRX1 \| DISEASES 3764 \| KCNJ8 \| DISEASES 2703 \| GJA8 \| DISEASES 4852 \| NPY \| DISEASES 7291 \| TWIST1 \| DISEASES 540 \| ATP7B \| DISEASES 3759 \| KCNJ2 \| DISEASES 583 \| BBS2 \| DISEASES 55154 \| MSTO1 \| DISEASES 3315 \| HSPB1 \| DISEASES 1215 \| CMA1 \| DISEASES 3630 \| INS \| DISEASES 3741 \| KCNA5 \| DISEASES 348 \| APOE \| DISEASES 59272 \| ACE2 \| DISEASES 9518 \| GDF15 \| DISEASES 54795 \| TRPM4 \| DISEASES 140628 \| GATA5 \| DISEASES 11046 \| SLC35D2 \| DISEASES 3958 \| LGALS3 \| DISEASES 55915 \| LANCL2 \| DISEASES 1401 \| CRP \| DISEASES 1116 \| CHI3L1 \| DISEASES 79589 \| RNF128 \| DISEASES 53 \| ACP2 \| DISEASES 187 \| APLNR \| DISEASES 6926 \| TBX3 \| DISEASES 3569 \| IL6 \| DISEASES 1101 \| CHAD \| DISEASES 1559 \| CYP2C9 \| DISEASES 9360 \| PPIG \| DISEASES 1419 \| CRYGB \| DISEASES 10152 \| ABI2 \| DISEASES 10060 \| ABCC9 \| DISEASES 4069 \| LYZ \| DISEASES 7450 \| VWF \| DISEASES 11019 \| LIAS \| DISEASES 845 \| CASQ2 \| DISEASES 23316 \| CUX2 \| DISEASES 10021 \| HCN4 \| DISEASES 4092 \| SMAD7 \| DISEASES 4087 \| SMAD2 \| DISEASES 3757 \| KCNH2 \| DISEASES 3674 \| ITGA2B \| DISEASES 6521 \| SLC4A1 \| DISEASES 495 \| ATP4A \| DISEASES 7077 \| TIMP2 \| DISEASES 25939 \| SAMHD1 \| DISEASES 3783 \| KCNN4 \| DISEASES 5595 \| MAPK3 \| DISEASES 22858 \| ICK \| DISEASES 50507 \| NOX4 \| DISEASES 3553 \| IL1B \| DISEASES 57731 \| SPTBN4 \| DISEASES 5067 \| CNTN3 \| DISEASES 6403 \| SELP \| DISEASES 56981 \| PRDM11 \| DISEASES 832 \| CAPZB \| DISEASES 51602 \| NOP58 \| DISEASES 3781 \| KCNN2 \| DISEASES 3383 \| ICAM1 \| DISEASES 3827 \| KNG1 \| DISEASES 4883 \| NPR3 \| DISEASES 9061 \| PAPSS1 \| DISEASES 1390 \| CREM \| DISEASES 5243 \| ABCB1 \| DISEASES 6717 \| SRI \| DISEASES 3746 \| KCNC1 \| DISEASES 5286 \| PIK3C2A \| DISEASES 7078 \| TIMP3 \| DISEASES 775 \| CACNA1C \| DISEASES 122953 \| JDP2 \| DISEASES 3705 \| ITPK1 \| DISEASES 463 \| ZFHX3 \| DISEASES 114799 \| ESCO1 \| DISEASES 2627 \| GATA6 \| DISEASES 207 \| AKT1 \| DISEASES 2702 \| GJA5 \| DISEASES 3782 \| KCNN3 \| DISEASES 5972 \| REN \| DISEASES 8497 \| PPFIA4 \| DISEASES 805 \| CALM2 \| DISEASES 185 \| AGTR1 \| DISEASES 166378 \| SPATA5 \| DISEASES 84651 \| SPINK7 \| DISEASES 4851 \| NOTCH1 \| DISEASES 138151 \| NACC2 \| DISEASES 6327 \| SCN2B \| DISEASES 738 \| VPS51 \| DISEASES 3606 \| IL18 \| DISEASES 5805 \| PTS \| DISEASES 2180 \| ACSL1 \| DISEASES 23704 \| KCNE4 \| DISEASES 115106 \| HAUS1 \| DISEASES 5741 \| PTH \| DISEASES 2697 \| GJA1 \| DISEASES 1360 \| CPB1 \| DISEASES 23250 \| ATP11A \| DISEASES 84976 \| DISP1 \| DISEASES 118611 \| C10orf90 \| DISEASES 81552 \| VOPP1 \| DISEASES 4838 \| NODAL \| DISEASES 391059 \| FRRS1 \| DISEASES 7547 \| ZIC3 \| DISEASES 7079 \| TIMP4 \| DISEASES 5468 \| PPARG \| DISEASES 51422 \| PRKAG2 \| DISEASES 3156 \| HMGCR \| DISEASES 776 \| CACNA1D \| DISEASES 22808 \| MRAS \| DISEASES 909 \| CD1A \| DISEASES 9992 \| KCNE2 \| DISEASES 1636 \| ACE \| DISEASES 90525 \| SHF \| DISEASES 808 \| CALM3 \| DISEASES 89765 \| RSPH1 \| DISEASES 6285 \| S100B \| DISEASES 160622 \| GRASP \| DISEASES 7412 \| VCAM1 \| DISEASES 3760 \| KCNJ3 \| DISEASES 213 \| ALB \| DISEASES 5473 \| PPBP \| DISEASES 5196 \| PF4 \| DISEASES 4724 \| NDUFS4 \| DISEASES 23305 \| ACSL6 \| DISEASES 4982 \| TNFRSF11B \| DISEASES 4846 \| NOS3 \| DISEASES 7373 \| COL14A1 \| DISEASES 55800 \| SCN3B \| DISEASES 118490 \| MSS51 \| DISEASES 339302 \| CPLX4 \| DISEASES 162681 \| C18orf54 \| DISEASES 4775 \| NFATC3 \| DISEASES 6240 \| RRM1 \| DISEASES 784 \| CACNB3 \| DISEASES 1632 \| ECI1 \| DISEASES 80150 \| ASRGL1 \| DISEASES 116285 \| ACSM1 \| DISEASES 56947 \| MFF \| DISEASES 51305 \| KCNK9 \| DISEASES 140838 \| NANP \| DISEASES 3308 \| HSPA4 \| DISEASES 255738 \| PCSK9 \| DISEASES 8988 \| HSPB3 \| DISEASES 5190 \| PEX6 \| DISEASES 5308 \| PITX2 \| DISEASES 6588 \| SLN \| DISEASES 1448 \| CSN3 \| DISEASES 154 \| ADRB2 \| DISEASES 8862 \| APLN \| DISEASES 3708 \| ITPR1 \| DISEASES 3777 \| KCNK3 \| DISEASES 2243 \| FGA \| DISEASES 3761 \| KCNJ4 \| DISEASES 51327 \| AHSP \| DISEASES 64805 \| P2RY12 \| DISEASES 126669 \| SHE \| DISEASES 8028 \| MLLT10 \| DISEASES 197259 \| MLKL \| DISEASES 2147 \| F2 \| DISEASES 134 \| ADORA1 \| DISEASES 5340 \| PLG \| DISEASES 171389 \| NLRP6 \| DISEASES 3265 \| HRAS \| DISEASES 6910 \| TBX5 \| DISEASES 8815 \| BANF1 \| DISEASES 10008 \| KCNE3 \| DISEASES 54207 \| KCNK10 \| DISEASES 836 \| CASP3 \| DISEASES 80227 \| PAAF1 \| DISEASES 5553 \| PRG2 \| DISEASES 8557 \| TCAP \| DISEASES 81832 \| NETO1 \| DISEASES 11238 \| CA5B \| DISEASES 3737 \| KCNA2 \| DISEASES 1604 \| CD55 \| DISEASES 3291 \| HSD11B2 \| DISEASES 9377 \| COX5A \| DISEASES 53905 \| DUOX1 \| DISEASES 3752 \| KCND3 \| DISEASES 783 \| CACNB2 \| DISEASES 124590 \| USH1G \| DISEASES 54822 \| TRPM7 \| DISEASES 9370 \| ADIPOQ \| DISEASES 90933 \| TRIM41 \| DISEASES 2149 \| F2R \| DISEASES 5345 \| SERPINF2 \| DISEASES 23212 \| RRS1 \| DISEASES 6330 \| SCN4B \| DISEASES 4312 \| MMP1 \| DISEASES 154865 \| IQUB \| DISEASES 1585 \| CYP11B2 \| DISEASES 1482 \| NKX2-5 \| DISEASES 3768 \| KCNJ12 \| DISEASES 114786 \| XKR4 \| DISEASES 3739 \| KCNA4 \| DISEASES 6331 \| SCN5A \| DISEASES 11016 \| ATF7 \| DISEASES 57649 \| PHF12 \| DISEASES 29110 \| TBK1 \| DISEASES 5155 \| PDGFB \| DISEASES 2192 \| FBLN1 \| DISEASES 6401 \| SELE \| DISEASES 4088 \| SMAD3 \| DISEASES 10052 \| GJC1 \| DISEASES 3751 \| KCND2 \| DISEASES 3043 \| HBB \| DISEASES 2152 \| F3 \| DISEASES 496 \| ATP4B \| DISEASES 2626 \| GATA4 \| DISEASES 1103 \| CHAT \| DISEASES 3753 \| KCNE1 \| DISEASES 9376 \| SLC22A8 \| DISEASES 10011 \| SRA1 \| DISEASES 1576 \| CYP3A4 \| DISEASES 3363 \| HTR7 \| DISEASES 80829 \| ZFP91 \| DISEASES 3266 \| ERAS \| DISEASES 857 \| CAV1 \| DISEASES 445329 \| SULT1A4 \| DISEASES 63826 \| SRR \| DISEASES 3762 \| KCNJ5 \| DISEASES 3329 \| HSPD1 \| DISEASES 4882 \| NPR2 \| DISEASES 113675 \| SDSL \| DISEASES 4306 \| NR3C2 \| DISEASES 7137 \| TNNI3 \| DISEASES 9536 \| PTGES \| DISEASES 259307 \| IL4I1 \| DISEASES 6818 \| SULT1A3 \| DISEASES 7273 \| TTN \| DISEASES 155 \| ADRB3 \| DISEASES 94241 \| TP53INP1 \| DISEASES 875 \| CBS \| DISEASES 4771 \| NF2 \| DISEASES 89932 \| PAPLN \| DISEASES 5144 \| PDE4D \| DISEASES 3767 \| KCNJ11 \| DISEASES 1861 \| TOR1A \| DISEASES 23481 \| PES1 \| DISEASES 2335 \| FN1 \| DISEASES 2326 \| FMO1 \| DISEASES 4635 \| MYL4 \| DISEASES 50488 \| MINK1 \| DISEASES 4625 \| MYH7 \| DISEASES 51703 \| ACSL5 \| DISEASES 4624 \| MYH6 \| DISEASES 7068 \| THRB \| DISEASES 26084 \| ARHGEF26 \| DISEASES 801 \| CALM1 \| DISEASES 287 \| ANK2 \| DISEASES 23224 \| SYNE2 \| DISEASES 10004 \| NAALADL1 \| DISEASES 58529 \| MYOZ1 \| DISEASES 799 \| CALCR \| DISEASES 9464 \| HAND2 \| DISEASES 147409 \| DSG4 \| DISEASES 4151 \| MB \| DISEASES 10092 \| ARPC5 \| DISEASES 116969 \| ART5 \| DISEASES 2157 \| F8 \| DISEASES 4311 \| MME \| DISEASES 6241 \| RRM2 \| DISEASES 1565 \| CYP2D6 \| DISEASES 3360 \| HTR4 \| DISEASES 57692 \| MAGEE1 \| DISEASES 4514 \| MT-CO3 \| DISEASES 9722 \| NOS1AP \| DISEASES 7179 \| TPTE \| DISEASES 23038 \| WDTC1 \| DISEASES 9859 \| CEP170 \| DISEASES 6262 \| RYR2 \| DISEASES 88 \| ACTN2 \| DISEASES 3775 \| KCNK1 \| DISEASES 183 \| AGT \| DISEASES 22796 \| COG2 \| DISEASES 3142 \| HLX \| DISEASES 2058 \| EPRS \| DISEASES 7779 \| SLC30A1 \| DISEASES 89796 \| NAV1 \| DISEASES 7139 \| TNNT2 \| DISEASES 23328 \| SASH1 \| DISEASES 389432 \| SAMD5 \| DISEASES 462 \| SERPINC1 \| DISEASES 1490 \| CTGF \| DISEASES 911 \| CD1C \| DISEASES 2117 \| ETV3 \| DISEASES 387104 \| SOGA3 \| DISEASES 4000 \| LMNA \| DISEASES 23493 \| HEY2 \| DISEASES 10654 \| PMVK \| DISEASES 3570 \| IL6R \| DISEASES 387119 \| CEP85L \| DISEASES 4881 \| NPR1 \| DISEASES 262 \| AMD1 \| DISEASES 51205 \| ACP6 \| DISEASES 153 \| ADRB1 \| DISEASES 1193 \| CLIC2 \| DISEASES 1268 \| CNR1 \| DISEASES 4803 \| NGF \| DISEASES 2010 \| EMD \| DISEASES 2316 \| FLNA \| DISEASES 22823 \| MTF2 \| DISEASES 84548 \| TMEM185A \| DISEASES 959 \| CD40LG \| DISEASES 51086 \| TNNI3K \| DISEASES 4774 \| NFIA \| DISEASES 1573 \| CYP2J2 \| DISEASES 23648 \| SSBP3 \| DISEASES 1557 \| CYP2C19 \| DISEASES 27063 \| ANKRD1 \| DISEASES 3745 \| KCNB1 \| DISEASES 11124 \| FAF1 \| DISEASES 186 \| AGTR2 \| DISEASES 11093 \| ADAMTS13 \| DISEASES 7422 \| VEGFA \| DISEASES 4318 \| MMP9 \| DISEASES 57158 \| JPH2 \| DISEASES 89822 \| KCNK17 \| DISEASES 149076 \| ZNF362 \| DISEASES 80312 \| TET1 \| DISEASES 2170 \| FABP3 \| DISEASES 84890 \| ADO \| DISEASES 4303 \| FOXO4 \| DISEASES 3710 \| ITPR3 \| DISEASES 1269 \| CNR2 \| DISEASES 4686 \| NCBP1 \| DISEASES 84909 \| C9orf3 \| DISEASES 2159 \| F10 \| DISEASES 2155 \| F7 \| DISEASES 3376 \| IARS \| DISEASES 3303 \| HSPA1A \| DISEASES 23564 \| DDAH2 \| DISEASES 3055 \| HCK \| DISEASES 11330 \| CTRC \| DISEASES 85366 \| MYLK2 \| DISEASES 4879 \| NPPB \| DISEASES 4878 \| NPPA \| DISEASES 4524 \| MTHFR \| DISEASES 1471 \| CST3 \| DISEASES 7056 \| THBD \| DISEASES 5293 \| PIK3CD \| DISEASES 765 \| CA6 \| DISEASES 285641 \| SLC36A3 \| DISEASES 22844 \| FRMPD1 \| DISEASES 10590 \| SCGN \| DISEASES 8514 \| KCNAB2 \| DISEASES 55301 \| OLAH \| DISEASES 1536 \| CYBB \| DISEASES 1906 \| EDN1 \| DISEASES 7222 \| TRPC3 \| DISEASES 54586 \| EQTN \| DISEASES 79886 \| CAAP1 \| DISEASES 79811 \| SLTM \| DISEASES 2281 \| FKBP1B \| DISEASES 415 \| ARSE \| DISEASES 7054 \| TH \| DISEASES 3709 \| ITPR2 \| DISEASES 26278 \| SACS \| DISEASES 60312 \| AFAP1 \| DISEASES 3736 \| KCNA1 \| DISEASES 50506 \| DUOX2 \| DISEASES 2869 \| GRK5 \| DISEASES 27032 \| ATP2C1 \| DISEASES 2596 \| GAP43 \| DISEASES 5627 \| PROS1 \| DISEASES 782 \| CACNB1 \| DISEASES 51520 \| LARS \| DISEASES 50801 \| KCNK4 \| DISEASES 79933 \| SYNPO2L \| DISEASES 64115 \| C10orf54 \| DISEASES 79001 \| VKORC1 \| DISEASES 4299 \| AFF1 \| DISEASES 831 \| CAST \| DISEASES 7702 \| ZNF143 \| DISEASES 51147 \| ING4 \| DISEASES 4689 \| NCF4 \| DISEASES 9373 \| PLAA \| DISEASES 23426 \| GRIP1 \| DISEASES 7110 \| TMF1 \| DISEASES 7478 \| WNT8A \| DISEASES 84709 \| MGARP \| DISEASES 23077 \| MYCBP2 \| DISEASES 2160 \| F11 \| DISEASES 729920 \| ISPD \| DISEASES 57703 \| CWC22 \| DISEASES 5861 \| RAB1A \| DISEASES 26115 \| TANC2 \| DISEASES 23066 \| CAND2 \| DISEASES 1385 \| CREB1 \| DISEASES 1111 \| CHEK1 \| DISEASES 4776 \| NFATC4 \| DISEASES 255928 \| SYT14 \| DISEASES 6336 \| SCN10A \| DISEASES 201456 \| FBXO15 \| DISEASES 8671 \| SLC4A4 \| DISEASES 3776 \| KCNK2 \| DISEASES 30820 \| KCNIP1 \| DISEASES 6324 \| SCN1B \| DISEASES 5999 \| RGS4 \| DISEASES 6660 \| SOX5 \| DISEASES 7124 \| TNF \| DISEASES 6474 \| SHOX2 \| DISEASES 51562 \| MBIP \| DISEASES 387 \| RHOA \| DISEASES 84290 \| CAPNS2 \| DISEASES 5817 \| PVR \| DISEASES 9498 \| SLC4A8 \| DISEASES 9734 \| HDAC9 \| DISEASES 116 \| ADCYAP1 \| DISEASES 3586 \| IL10 \| DISEASES 133396 \| IL31RA \| DISEASES 22862 \| FNDC3A \| DISEASES 339487 \| ZBTB8OS \| DISEASES 347273 \| MURC \| DISEASES 7881 \| KCNAB1 \| DISEASES 30819 \| KCNIP2 \| DISEASES 813 \| CALU \| DISEASES 253970 \| SFTA3 \| DISEASES 149466 \| C1orf210 \| DISEASES 9312 \| KCNB2 \| DISEASES 55845 \| BRK1 \| DISEASES 3347 \| HTN3 \| DISEASES 142891 \| SAMD8 \| DISEASES 488 \| ATP2A2 \| DISEASES 4607 \| MYBPC3 \| DISEASES 6510 \| SLC1A5 \| DISEASES 11153 \| FICD \| DISEASES 8972 \| MGAM \| DISEASES 84525 \| HOPX \| DISEASES 9628 \| RGS6 \| DISEASES 101 \| ADAM8 \| DISEASES 27229 \| TUBGCP4 \| DISEASES 3316 \| HSPB2 \| DISEASES 7138 \| TNNT1 \| DISEASES 100302740 \| FAS-AS1 \| DISEASES 102723508 \| KANTR \| DISEASES 378805 \| LINC-PINT \| DISEASES 104564225 \| MHRT \| DISEASES 103752588 \| PACERR \| DISEASES 9304 \| SNORD22 \| DISEASES 25826 \| SNORD82 \| DISEASES
Locus	(Waiting for update.)

Disease ID	380
Disease	atrial fibrillation
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:170) HP:0001297 \| Cerebral vascular events \| 893 HP:0001907 \| Thromboembolic disease \| 153 HP:0001635 \| Congestive heart failure \| 136 HP:0002140 \| Ischemic stroke \| 125 HP:0001658 \| Myocardial infarction \| 45 HP:0001649 \| Tachycardia \| 36 HP:0000822 \| Hypertension \| 34 HP:0011675 \| Arrhythmias \| 30 HP:0001639 \| Hypertrophic cardiomyopathy \| 25 HP:0002326 \| TIA \| 24 HP:0001677 \| Coronary artery disease \| 22 HP:0001638 \| Cardiomyopathy \| 19 HP:0000836 \| Overactive thyroid \| 16 HP:0012622 \| Chronic kidney disease \| 15 HP:0003774 \| End-stage renal failure \| 15 HP:0010535 \| Sleep apnea \| 14 HP:0000819 \| Diabetes mellitus \| 14 HP:0002104 \| Absence of spontaneous respiration \| 14 HP:0001718 \| Mitral stenosis \| 13 HP:0001662 \| Bradycardia \| 13 HP:0000716 \| Depression \| 10 HP:0002870 \| Obstructive sleep apnea \| 10 HP:0001650 \| Valvular aortic stenosis \| 9 HP:0011704 \| Sick sinus syndrome \| 9 HP:0001712 \| Left ventricular hypertrophy \| 9 HP:0001513 \| Obesity \| 8 HP:0002170 \| Intracranial hemorrhage \| 8 HP:0100543 \| Cognitive deficits \| 8 HP:0001653 \| Mitral valve insufficiency \| 8 HP:0001716 \| Wolff-Parkinson-White syndrome \| 8 HP:0004756 \| Ventricular tachycardia \| 8 HP:0001727 \| Thromboembolic stroke \| 8 HP:0001631 \| Atria septal defect \| 8 HP:0002584 \| Intestinal hemorrhage \| 7 HP:0001279 \| Syncope \| 7 HP:0004755 \| Supraventricular tachycardia \| 7 HP:0011710 \| Bundle-branch block \| 7 HP:0001714 \| Ventricular hypertrophy \| 7 HP:0002637 \| Brain ischemia \| 6 HP:0002239 \| Gastrointestinal hemorrhage \| 6 HP:0004757 \| Paroxysmal atrial fibrillation \| 6 HP:0002617 \| Aneurysmal dilatation \| 5 HP:0000821 \| Underactive thyroid \| 5 HP:0011713 \| Left bundle branch block \| 5 HP:0003765 \| Psoriasis \| 5 HP:0004749 \| Atrial flutter \| 5 HP:0002527 \| Falls \| 4 HP:0001250 \| Seizures \| 4 HP:0000083 \| Renal insufficiency \| 4 HP:0006510 \| Chronic obstructive pulmonary disease \| 4 HP:0000726 \| Dementia \| 4 HP:0001370 \| Rheumatoid arthritis \| 4 HP:0002092 \| Pulmonary artery hypertension \| 4 HP:0001342 \| Intracerebral hemorrhage \| 4 HP:0002020 \| Heartburn \| 3 HP:0001268 \| Mental deterioration \| 3 HP:0100806 \| Sepsis \| 3 HP:0001645 \| Sudden cardiac death \| 3 HP:0004763 \| Episodic supraventricular tachycardia \| 3 HP:0000802 \| Erectile dysfunction \| 3 HP:0001678 \| Atrioventricular block \| 3 HP:0000739 \| Anxiety \| 3 HP:0002621 \| Atherosclerosis \| 3 HP:0004309 \| Pre-excitation syndrome \| 3 HP:0002204 \| Pulmonary embolism \| 3 HP:0001644 \| Congestive cardiomyopathy \| 3 HP:0002094 \| Dyspnea \| 3 HP:0001698 \| Pericardial effusions \| 3 HP:0001962 \| Palpitations \| 3 HP:0002615 \| Low blood pressure \| 3 HP:0001681 \| Angina pectoris \| 2 HP:0003003 \| Colon cancer \| 2 HP:0004950 \| Peripheral artery disease \| 2 HP:0011995 \| Atrial septal aneurysm \| 2 HP:0002647 \| Aortic dissection \| 2 HP:0002625 \| Blood clot in a deep vein \| 2 HP:0000093 \| Proteinuria \| 2 HP:0100584 \| Endocarditis \| 2 HP:0002315 \| Headaches \| 2 HP:0001657 \| Prolonged QT interval \| 2 HP:0005301 \| Persistent left superior vena cava \| 2 HP:0001369 \| Arthritis \| 2 HP:0011034 \| Amyloid disease \| 2 HP:0011877 \| Increased mean platelet volume \| 2 HP:0001627 \| Congenital heart defects \| 2 HP:0005162 \| Left ventricular impairment \| 2 HP:0100749 \| Thoracic pain \| 2 HP:0012668 \| Situational syncope \| 2 HP:0002459 \| Dysautonomia \| 2 HP:0001945 \| Fever \| 1 HP:0002381 \| Aphasia \| 1 HP:0030843 \| Cardiac amyloidosis \| 1 HP:0006554 \| Acute hepatic failure \| 1 HP:0002359 \| Frequent falls \| 1 HP:0100724 \| Hypercoagulability \| 1 HP:0006528 \| Chronic lung disease \| 1 HP:0002665 \| Lymphoma \| 1 HP:0005115 \| arrhythmias, Supraventricular \| 1 HP:0100790 \| Hernia \| 1 HP:0001655 \| Patent foramen ovale \| 1 HP:0100279 \| Ulcerative colitis \| 1 HP:0012452 \| Restless legs \| 1 HP:0001701 \| Pericarditis \| 1 HP:0100598 \| Pulmonary oedema \| 1 HP:0004398 \| Peptic ulcer \| 1 HP:0002344 \| Progressive neurologic deterioration \| 1 HP:0001733 \| Pancreatic inflammation \| 1 HP:0002155 \| Increased triglycerides \| 1 HP:0002301 \| Hemiplegia \| 1 HP:0001682 \| Subvalvular aortic stenosis \| 1 HP:0003198 \| Myopathic changes \| 1 HP:0001288 \| Gait disturbance \| 1 HP:0000767 \| Funnel chest \| 1 HP:0007359 \| Partial seizures \| 1 HP:0002608 \| Celiac disease \| 1 HP:0009792 \| Teratoma \| 1 HP:0012735 \| Coughing \| 1 HP:0007430 \| Generalized edema \| 1 HP:0001723 \| Restrictive cardiomyopathy \| 1 HP:0100665 \| Angiooedema \| 1 HP:0003074 \| High blood glucose \| 1 HP:0001695 \| Cardiac arrest \| 1 HP:0001399 \| Liver failure \| 1 HP:0002189 \| Excessive daytime sleepiness \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0002583 \| Colitis \| 1 HP:0002669 \| Osteosarcoma \| 1 HP:0000939 \| Osteoporosis \| 1 HP:0001262 \| Somnolence \| 1 HP:0003560 \| Muscular dystrophy \| 1 HP:0011703 \| Sinus tach \| 1 HP:0001873 \| Low platelet count \| 1 HP:0001651 \| Thoracic situs inversus \| 1 HP:0002917 \| Low blood magnesium levels \| 1 HP:0005157 \| Concentric hypertrophic cardiomyopathy \| 1 HP:0004420 \| Arterial thrombosis \| 1 HP:0002664 \| Neoplasia \| 1 HP:0001824 \| Weight loss \| 1 HP:0002018 \| Nausea \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0003077 \| Hyperlipidemia \| 1 HP:0012248 \| Lengthened PR interval on EKG \| 1 HP:0012625 \| Stage 3 chronic kidney disease \| 1 HP:0002758 \| Osteoarthritis \| 1 HP:0001735 \| Acute pancreatitis \| 1 HP:0001659 \| Aortic insufficiency \| 1 HP:0011712 \| Right bundle-branch block \| 1 HP:0001663 \| Ventricular fibrillation \| 1 HP:0004308 \| Ventricular arrhythmia \| 1 HP:0002153 \| Elevated serum potassium levels \| 1 HP:0001636 \| Tetrology of fallot \| 1 HP:0002015 \| Swallowing difficulty \| 1 HP:0004936 \| Blood clot in vein \| 1 HP:0002013 \| Emesis \| 1 HP:0000969 \| Dropsy \| 1 HP:0011748 \| Adrenocorticotropic hormone deficiency \| 1 HP:0012377 \| Hemianopia \| 1 HP:0001669 \| Transposition of the great arteries \| 1 HP:0000820 \| Thyroid abnormality \| 1 HP:0005180 \| Tricuspid insufficiency \| 1 HP:0000832 \| Primary hypothyroidism \| 1 HP:0002090 \| Pneumonia \| 1 HP:0002039 \| Anorexia \| 1 HP:0002069 \| Generalized tonic clonic seizures \| 1 HP:0012531 \| Pain \| 1 HP:0000872 \| Hashimoto's thyroiditis \| 1 HP:0001402 \| Hepatocellular carcinoma \| 1 HP:0010536 \| Central sleep apnoea \| 1 HP:0002383 \| Encephalitis \| 1 HP:0030741 \| Teratoma of the mediastinum \| 1

Disease ID	380
Disease	atrial fibrillation
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:46)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs10033464	17603472	5308	PITX2	umls:C0004238	GAD	[Variants conferring risk of atrial fibrillation on chromosome 4q25.]	0.01183516	2007	NA	4	110799605	T	G
rs10489717	17903304	83872	HMCN1	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	HMCN1	1	185954443	G	A
rs10492755	17903304	54715	RBFOX1	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	RBFOX1	16	7511457	C	T
rs10501920	17903304	53942	CNTN5	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	CNTN5	11	99622442	C	G
rs10511311	17903304	4345	CD200	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	CD200;SLC9C1	3	112336992	A	T
rs10821415	22544366	84909	C9orf3	umls:C0004238	GWASCAT	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	0.24	2012	C9orf3	9	94951177	C	A
rs1152591	22544366	23224	SYNE2	umls:C0004238	GWASCAT	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	0.24	2012	ESR2;SYNE2	14	64214130	A	G
rs1152591	22544366	2100	ESR2	umls:C0004238	GWASCAT	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	0.12	2012	ESR2;SYNE2	14	64214130	A	G
rs11973337	17903304	9723	SEMA3E	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	NA	7	83662101	A	G
rs1298340	17903304	5890	RAD51B	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	RAD51B	14	68210775	G	C
rs13038095	20173747	55959	SULF2	umls:C0004238	GAD	[Common variants in KCNN3 are associated with lone atrial fibrillation.]	0.002367032	2010	NA	20	47796832	G	T
rs1314913	17903304	5890	RAD51B	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	RAD51B	14	68232877	C	T
rs13376333	20173747	3782	KCNN3	umls:C0004238	GWASCAT	Common variants in KCNN3 are associated with lone atrial fibrillation.	0.242367032	2010	KCNN3	1	154841877	C	T
rs13376333	20173747	3782	KCNN3	umls:C0004238	GAD	[Common variants in KCNN3 are associated with lone atrial fibrillation.]	0.242367032	2010	KCNN3	1	154841877	C	T
rs1427828	17903304	1848	DUSP6	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	LOC105369889	12	89368722	C	G
rs147750704	NA	3759	KCNJ2	umls:C0004238	CLINVAR	NA	0.12272435	NA	KCNJ2	17	70175316	G	A
rs1558145	17903304	139538	VENTXP1	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	NA	X	26637619	C	T
rs16851040	17903304	92369	SPSB4	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	SPSB4	3	141073523	A	G
rs17042171	19597492	5308	PITX2	umls:C0004238	GAD	[Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.]	0.01183516	2009	NA	4	110787131	C	A
rs17375901	19597492	4878	NPPA	umls:C0004238	GAD	[Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.]	0.005091382	2009	MTHFR	1	11792459	C	T
rs17375901	19597492	4524	MTHFR	umls:C0004238	GAD	[Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.]	0.122367032	2009	MTHFR	1	11792459	C	T
rs17375901	19597492	4524	MTHFR	umls:C0004238	GWASCAT	Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.	0.122367032	2009	MTHFR	1	11792459	C	T
rs1751382	17903304	5890	RAD51B	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	RAD51B	14	68225933	C	T
rs199473060	NA	6331	SCN5A	umls:C0004238	CLINVAR	NA	0.262732561	NA	SCN5A	3	38622468	C	T
rs199473111	NA	6331	SCN5A	umls:C0004238	CLINVAR	NA	0.262732561	NA	SCN5A	3	38606007	C	T
rs199473260	NA	6331	SCN5A	umls:C0004238	CLINVAR	NA	0.262732561	NA	SCN5A	3	38555720	T	C
rs199473335	NA	6331	SCN5A	umls:C0004238	CLINVAR	NA	0.262732561	NA	SCN5A	3	38550411	G	T
rs2040862	22544366	7478	WNT8A	umls:C0004238	GWASCAT	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	0.24	2012	WNT8A	5	138084300	C	T
rs2106261	22544366	463	ZFHX3	umls:C0004238	GWASCAT	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	0.244734064	2012	ZFHX3	16	73017721	C	T
rs2106261	19597492	463	ZFHX3	umls:C0004238	GWASCAT	Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.	0.244734064	2009	ZFHX3	16	73017721	C	T
rs2106261	19597492	463	ZFHX3	umls:C0004238	GAD	[Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.]	0.244734064	2009	ZFHX3	16	73017721	C	T
rs2200733	17603472	5308	PITX2	umls:C0004238	GAD	[Variants conferring risk of atrial fibrillation on chromosome 4q25.]	0.01183516	2007	NA	4	110789013	C	T
rs2200733	19597491	5308	PITX2	umls:C0004238	GAD	[A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.]	0.01183516	2009	NA	4	110789013	C	T
rs2421954	17903304	51057	WDPCP	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	WDPCP	2	63527141	T	C
rs324735	17903304	8615	USO1	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	USO1	4	75783861	A	T
rs3807989	22544366	857	CAV1	umls:C0004238	GWASCAT	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	0.24	2012	CAV1	7	116546187	A	G
rs412253	17903304	5099	PCDH7	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	NA	4	31441128	T	A
rs4776472	17903304	6176	RPLP1	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	NA	15	69714534	G	A
rs6666258	22544366	3782	KCNN3	umls:C0004238	GWASCAT	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	0.242367032	2012	KCNN3	1	154841792	G	C
rs6843082	20173747	5308	PITX2	umls:C0004238	GAD	[Common variants in KCNN3 are associated with lone atrial fibrillation.]	0.01183516	2010	NA	4	110796911	G	A
rs7164883	22544366	10021	HCN4	umls:C0004238	GWASCAT	Meta-analysis identifies six new susceptibility loci for atrial fibrillation.	0.24	2012	HCN4	15	73359833	A	G
rs7193343	19597491	463	ZFHX3	umls:C0004238	GWASCAT	A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.	0.244734064	2009	ZFHX3	16	72995261	T	C
rs7193343	19597491	463	ZFHX3	umls:C0004238	GAD	[A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.]	0.244734064	2009	ZFHX3	16	72995261	T	C
rs7781585	17903304	4189	DNAJB9	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	NA	7	108824307	C	T
rs935329	17903304	6938	TCF12	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	TCF12	15	57217763	C	G
rs958546	17903304	220416	LRRC63	umls:C0004238	GAD	[No association attained genome-wide significance, but several intriguing findings emerged. Notably, we replicated associations of chromosome 9p21 with major CVD. Additional studies are needed to validate these results. Finding genetic variants associated ]	0.002367032	2007	LRRC63	13	46259582	G	C

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:504)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	8008968	rs226473	T	C	rs226473	21846873	9.52E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11852110	rs13306556	C	T	rs13306556	21846873	2.90E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11852516	rs17375901	C	T	rs17375901	19597492	6.00E-07	NA	1.26	NA	3,413 cases; 37,105 referents	NOPOP(40518)	ALL(40518)	NOPOP(40518)	ALL(40518)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs17375901-T	NA	C	MTHFR
1	11860117	rs13306553	A	G	rs13306553	21846873	2.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11860843	rs17037390	G	A	rs17037390	21846873	8.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11862047	rs17037396	C	T	rs17037396	21846873	2.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11862778	rs17367504	A	G	rs17367504	21846873	3.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11863057	rs2066470	G	A	rs2066470	21846873	1.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11865804	rs13306561	A	G	rs13306561	21846873	3.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11870383	rs17037425	G	A	rs17037425	21846873	4.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11904076	rs198358	T	C	rs198358	21846873	1.15E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	11905974	rs5068	A	G	rs5068	21846873	2.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	17371298	rs34916635	C	T	rs34916635	21846873	1.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	18563991	rs4920311	G	C	rs4920311	21846873	6.60E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	36934805	rs3917991	C	G	rs3917991	21846873	6.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	92209311	rs2029356	T	C	rs2029356	21846873	4.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	92211020	rs17131547	G	A	rs17131547	21846873	3.60E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	101711783	rs2031959	T	G	rs2031959	21846873	8.70E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	112428953	rs1767283	T	C	rs1767283	24850809	2.80E-10	NA	0.86	[0.59-1.13] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1767283-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	112433863	rs605604	C	A	rs605604	24850809	2.17E-10	NA	0.87	[0.6-1.14] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs605604-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	112437344	rs2798334	T	C	rs2798334	24850809	8.00E-11	NA	0.92	[0.64-1.19] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2798334-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	112451447	rs2120436	C	T	rs2120436	24850809	4.38E-09	NA	0.84	[0.56-1.12] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2120436-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	112454822	rs12090194	C	T	rs12090194	24850809	3.08E-09	NA	0.84	[0.56-1.11] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12090194-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	112461902	rs1443926	A	G	rs1443926	24850809	5.12E-09	NA	0.81	[0.54-1.08] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1443926-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	112464004	rs1545300	C	T	rs1545300	24850809	5.06E-09	NA	0.82	[0.55-1.09] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1545300-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T,C
1	112471029	rs1443927	C	G	rs1443927	24850809	5.35E-09	NA	0.95	[0.63-1.27] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1443927-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	112480536	rs12145374	A	C	rs12145374	24850809	2.78E-10	NA	1.46	[1.01-1.91] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12145374-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	147231373	rs2232190	A	G	rs2232190	21846873	2.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	154418879	rs4537545	C	T	rs4537545	21846873	6.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	154420778	rs7529229	T	C	rs7529229	21846873	8.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	154421354	rs28638007	T	C	rs28638007	21846873	4.90E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	154422067	rs4845625	T	C	rs4845625	21846873	4.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	154814268	rs6666258	G	C	rs6666258	22544366	2.00E-14	NA	1.18	[1.13-1.23]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs6666258-C	Meta-Analysis	C	KCNN3
1	154814353	rs13376333	C	T	rs13376333	20173747	2.00E-21	NA	1.52	[1.40-1.64]	1,335 European descent cases; 12,844 European descent controls	European(14179)	ALL(14179)	EUR(14179)	ALL(14179)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs13376333-T	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	154900721	rs4578216	T	C	rs4578216	21846873	4.90E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	161192316	rs6413453	G	A	rs6413453	21846873	4.46E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	170569317	rs3903239	A	G	rs3903239	22544366	8.00E-14	NA	1.14	[1.10-1.17]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs3903239-G	Meta-Analysis	T	NA
1	179077613	rs17277288	T	C	rs17277288	21846873	2.70E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	190259941	rs567393	T	C	rs567393	21846873	4.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	206626828	rs2483058	C	G	rs2483058	21846873	4.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
1	232174775	rs1411771	T	C	rs1411771	23705025	0.0000206	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	DISC1
1	237599023	rs17633019	G	A	rs17633019	21846873	3.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
2	21260601	rs550619	G	A	rs550619	21846873	6.90E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
2	41531398	rs13385952	T	C	rs13385952	21846873	9.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
2	66746532	rs4300815	C	A	rs4300815	24850809	8.87E-09	NA	1.23	[0.81-1.64] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4300815-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
2	66749610	rs4430933	A	G	rs4430933	24850809	3.11E-08	NA	1.13	[0.73-1.53] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4430933-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	66750152	rs6742861	T	C	rs6742861	24850809	8.29E-09	NA	1.21	[0.8-1.63] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6742861-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
2	66756413	rs11677371	A	G	rs11677371	24850809	3.24E-08	NA	1.15	[0.74-1.56] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11677371-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	66756976	rs3891585	A	G	rs3891585	24850809	2.30E-08	NA	1.16	[0.75-1.56] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3891585-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	66759843	rs11693646	G	A	rs11693646	24850809	4.92E-09	NA	1.26	[0.84-1.68] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11693646-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	66760079	rs11678354	T	A	rs11678354	24850809	5.00E-09	NA	1.26	[0.84-1.68] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11678354-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
2	66760311	rs4433986	A	G	rs4433986	24850809	3.07E-08	NA	1.16	[0.75-1.56] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4433986-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	66762411	rs7603236	C	T	rs7603236	24850809	4.10E-08	NA	1.16	[0.74-1.57] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7603236-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
2	66764997	rs10865355	A	G	rs10865355	24850809	4.51E-08	NA	1.18	[0.75-1.6] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10865355-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	66768975	rs17625724	G	A	rs17625724	24850809	9.13E-09	NA	1.27	[0.84-1.7] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs17625724-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	66770035	rs11678796	G	A	rs11678796	24850809	1.06E-08	NA	1.27	[0.83-1.7] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11678796-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	66779866	rs3772026	G	A	rs3772026	24850809	2.14E-08	NA	1.26	[0.82-1.7] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3772026-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
2	68322579	rs11681944	G	A	rs11681944	23705025	0.0000328	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA
2	113580094	rs3917385	G	A	rs3917385	21846873	1.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
2	179489726	rs12614435	A	G	rs12614435	21846873	9.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
3	19384526	rs13316471	C	T	rs13316471	21846873	5.50E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
3	38442504	rs2234628	G	A	rs2234628	24850809	4.00E-10	NA	1.9	[1.31-2.5] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2234628-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38455901	rs12636358	G	A	rs12636358	24850809	4.66E-10	NA	2.01	[1.37-2.64] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12636358-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38510346	rs2284816	T	C	rs2284816	24850809	3.36E-10	NA	2.03	[1.39-2.66] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2284816-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38512619	rs12637034	T	C	rs12637034	24850809	2.27E-10	NA	2.07	[1.43-2.7] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12637034-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38525588	rs12636077	G	A	rs12636077	24850809	2.51E-10	NA	2.06	[1.42-2.7] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12636077-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38561079	rs17037809	G	A	rs17037809	24850809	2.32E-12	NA	2.15	[1.55-2.75] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs17037809-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38569764	rs12631864	G	A	rs12631864	24850809	2.62E-12	NA	2.14	[1.54-2.74] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12631864-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38591689	rs7429945	T	C	rs7429945	24850809	4.27E-14	NA	0.99	[0.73-1.24] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7429945-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38593393	rs12053903	T	C	rs12053903	24850809	2.38E-12	NA	0.98	[0.71-1.26] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12053903-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38594973	rs7638909	T	G	rs7638909	24850809	2.91E-14	NA	1.32	[0.98-1.66] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7638909-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38599037	rs6793245	G	A	rs6793245	24850809	1.40E-11	NA	0.99	[0.7-1.27] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6793245-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38601556	rs6799868	T	C	rs6799868	24850809	4.69E-12	NA	0.99	[0.71-1.27] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6799868-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38602855	rs3935472	G	A	rs3935472	24850809	2.37E-14	NA	2.55	[1.89-3.2] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3935472-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38605732	rs7374138	G	C	rs7374138	24850809	1.38E-18	NA	2.31	[1.8-2.83] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7374138-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38607229	rs9812912	C	T	rs9812912	24850809	3.11E-18	NA	2.24	[1.74-2.75] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9812912-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38609334	rs9861242	A	G	rs9861242	24850809	9.60E-12	NA	1.57	[1.12-2.02] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9861242-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38611704	rs4130467	C	T	rs4130467	24850809	1.48E-12	NA	1.62	[1.17-2.07] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4130467-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38624253	rs3922844	T	C	rs3922844	24850809	1.78E-08	NA	1.42	[0.92-1.91] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3922844-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38624343	rs3922843	A	G	rs3922843	24850809	1.88E-08	NA	1.13	[0.74-1.53] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3922843-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38629814	rs6599214	G	A	rs6599214	24850809	3.02E-08	NA	2.38	[1.54-3.22] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599214-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38632047	rs7374040	C	G	rs7374040	24850809	1.70E-16	NA	2.73	[2.08-3.38] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7374040-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38632630	rs10154914	T	A	rs10154914	24850809	8.88E-13	NA	1.23	[0.89-1.56] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10154914-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38633110	rs9311191	T	C	rs9311191	24850809	1.19E-12	NA	1.21	[0.88-1.54] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9311191-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38633923	rs11708996	G	C	rs11708996	24850809	3.63E-11	NA	2.82	[1.99-3.66] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11708996-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38634142	rs7374540	C	A	rs7374540	24850809	3.40E-14	NA	1.38	[1.02-1.73] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7374540-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38634343	rs7373862	G	A	rs7373862	24850809	4.04E-13	NA	1.46	[1.07-1.85] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7373862-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38635072	rs9311194	G	A	rs9311194	24850809	6.43E-13	NA	1.21	[0.88-1.54] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9311194-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38638202	rs3935184	C	G	rs3935184	24850809	2.28E-13	NA	1.39	[1.02-1.77] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3935184-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38638390	rs10212202	G	C	rs10212202	24850809	9.05E-13	NA	1.18	[0.86-1.5] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10212202-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38641084	rs9833775	C	T	rs9833775	24850809	4.18E-11	NA	1.69	[1.19-2.19] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9833775-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38643785	rs11714074	C	T	rs11714074	24850809	1.15E-10	NA	1.67	[1.16-2.17] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11714074-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38645420	rs1805124	T	C	rs1805124	24850809	9.89E-13	NA	1.07	[0.77-1.36] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1805124-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38646423	rs7428779	C	T	rs7428779	24850809	5.17E-11	NA	1.68	[1.18-2.18] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7428779-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38647047	rs11711602	C	T	rs11711602	24850809	5.43E-11	NA	1.68	[1.18-2.18] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11711602-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38684466	rs6768664	C	A	rs6768664	24850809	1.90E-08	NA	3.47	[2.26-4.68] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6768664-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38719901	rs9851710	C	A	rs9851710	24850809	6.52E-20	NA	1.95	[1.53-2.37] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9851710-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38719901	rs9851710	C	A	rs9851710	24850809	7.81E-10	NA	2.15	[1.47-2.84] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9851710-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38721308	rs7373154	T	C	rs7373154	24850809	4.49E-08	NA	0.76	[0.49-1.03] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7373154-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38723217	rs7633988	T	A	rs7633988	24850809	2.79E-12	NA	2.97	[2.13-3.8] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7633988-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38723217	rs7633988	T	A	rs7633988	24850809	7.93E-23	NA	2.55	[2.04-3.05] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7633988-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38726685	rs7374165	A	C	rs7374165	24850809	1.10E-08	NA	1.85	[1.21-2.48] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7374165-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38726685	rs7374165	A	C	rs7374165	24850809	1.41E-09	NA	1.2	[0.81-1.59] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7374165-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38737984	rs6599239	G	A	rs6599239	24850809	4.41E-08	NA	1.88	[1.2-2.55] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599239-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38738717	rs6599240	G	A	rs6599240	24850809	4.53E-27	NA	2.77	[2.27-3.27] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599240-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38738717	rs6599240	G	A	rs6599240	24850809	7.17E-19	NA	1.39	[1.09-1.7] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599240-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38739845	rs6599242	A	G	rs6599242	24850809	2.96E-08	NA	1.83	[1.19-2.48] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599242-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38742229	rs11129799	T	C	rs11129799	24850809	1.78E-11	NA	1.67	[1.18-2.16] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11129799-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38744370	rs11129800	C	T	rs11129800	24850809	2.95E-15	NA	2.7	[2.03-3.38] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11129800-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38747277	rs6599243	C	T	rs6599243	24850809	1.14E-09	NA	1.9	[1.29-2.51] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599243-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38747872	rs6599247	T	C	rs6599247	24850809	1.02E-09	NA	1.9	[1.29-2.51] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599247-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38749026	rs6599248	T	A	rs6599248	24850809	1.14E-11	NA	1.67	[1.19-2.16] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599248-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38750375	rs11129801	A	G	rs11129801	24850809	6.03E-12	NA	2.17	[1.55-2.78] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11129801-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38750436	rs11129802	T	C	rs11129802	24850809	8.92E-10	NA	1.9	[1.29-2.51] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11129802-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38752790	rs11710006	A	T	rs11710006	24850809	1.89E-08	NA	1.45	[0.94-1.96] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11710006-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38752790	rs11710006	A	T	rs11710006	24850809	3.51E-10	NA	0.99	[0.68-1.3] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11710006-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38752935	rs6783110	A	G	rs6783110	24850809	1.28E-24	NA	1.48	[1.19-1.76] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6783110-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38752935	rs6783110	A	G	rs6783110	24850809	8.75E-38	NA	3.03	[2.57-3.49] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6783110-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38752968	rs11129803	T	C	rs11129803	24850809	4.56E-11	NA	1.91	[1.34-2.48] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11129803-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38756498	rs11928905	T	C	rs11928905	24850809	1.87E-11	NA	1.91	[1.35-2.47] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11928905-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38756566	rs11924846	C	T	rs11924846	24850809	3.72E-25	NA	1.44	[1.17-1.72] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11924846-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38756566	rs11924846	C	T	rs11924846	24850809	9.69E-39	NA	2.96	[2.52-3.41] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11924846-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38757235	rs6794914	C	T	rs6794914	24850809	1.39E-12	NA	2.16	[1.56-2.75] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6794914-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38757235	rs6794914	C	T	rs6794914	24850809	4.43E-08	NA	1.02	[0.65-1.38] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6794914-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38759465	rs9990137	A	G	rs9990137	24850809	1.03E-14	NA	1.9	[1.42-2.38] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9990137-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38759465	rs9990137	A	G	rs9990137	24850809	3.61E-13	NA	1.09	[0.8-1.38] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9990137-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38760506	rs6805187	C	A	rs6805187	24850809	7.67E-11	NA	1.22	[0.85-1.59] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6805187-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38760506	rs6805187	C	A	rs6805187	24850809	9.24E-15	NA	2.38	[1.78-2.98] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6805187-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38763500	rs7617547	G	C	rs7617547	24850809	4.05E-18	NA	2.17	[1.68-2.66] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7617547-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38763863	rs6771157	G	C	rs6771157	24850809	2.76E-09	NA	1.15	[0.77-1.53] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6771157-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38763863	rs6771157	G	C	rs6771157	24850809	6.20E-11	NA	2.08	[1.45-2.7] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6771157-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38764782	rs4076737	G	T	rs4076737	24850809	1.22E-39	NA	2.86	[2.44-3.29] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4076737-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38764782	rs4076737	G	T	rs4076737	24850809	1.32E-25	NA	1.39	[1.13-1.65] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4076737-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38764998	rs12632942	A	G	rs12632942	24850809	2.27E-11	NA	1.03	[0.73-1.33] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12632942-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38764998	rs12632942	A	G	rs12632942	24850809	4.78E-10	NA	1.57	[1.07-2.06] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12632942-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38765490	rs7430477	C	T	rs7430477	24850809	4.38E-30	NA	2.58	[2.14-3.02] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7430477-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38765490	rs7430477	C	T	rs7430477	24850809	9.56E-24	NA	1.39	[1.12-1.66] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7430477-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38766338	rs9825762	T	C	rs9825762	24850809	2.66E-11	NA	1.67	[1.18-2.16] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9825762-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38766675	rs6795970	A	G	rs6795970	22544366	2.20E-05	NA	NA	NA	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Meta-Analysis	G	SCN10A
3	38766675	rs6795970	A	G	rs6795970	24850809	4.79E-40	NA	2.85	[2.43-3.27] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6795970-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38766675	rs6795970	A	G	rs6795970	24850809	8.79E-26	NA	1.38	[1.12-1.64] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6795970-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38766701	rs6791171	C	T	rs6791171	24850809	2.66E-11	NA	1.91	[1.35-2.48] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6791171-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38767315	rs6801957	T	C	rs6801957	24850809	7.00E-41	NA	2.94	[2.51-3.36] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6801957-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38767315	rs6801957	T	C	rs6801957	24850809	8.00E-27	NA	1.44	[1.17-1.70] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6801957-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38770639	rs7433306	C	G	rs7433306	24850809	1.21E-39	NA	2.77	[2.36-3.18] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7433306-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38770639	rs7433306	C	G	rs7433306	24850809	5.17E-26	NA	1.36	[1.1-1.61] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7433306-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38771464	rs6780103	G	A	rs6780103	24850809	1.29E-15	NA	1.78	[1.35-2.22] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6780103-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38771464	rs6780103	G	A	rs6780103	24850809	2.26E-08	NA	0.76	[0.5-1.03] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6780103-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38771925	rs6790396	C	G	rs6790396	24850809	4.31E-26	NA	1.33	[1.08-1.57] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6790396-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38771925	rs6790396	C	G	rs6790396	24850809	4.84E-39	NA	2.68	[2.28-3.08] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6790396-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38772864	rs13096893	G	A	rs13096893	24850809	5.96E-12	NA	1.85	[1.32-2.38] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs13096893-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38774832	rs6800541	C	T	rs6800541	22544366	2.80E-06	NA	NA	NA	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Meta-Analysis	T	SCN10A
3	38774832	rs6800541	C	T	rs6800541	24850809	2.74E-39	NA	2.66	[2.26-3.06] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6800541-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38774832	rs6800541	C	T	rs6800541	24850809	8.35E-26	NA	1.3	[1.06-1.55] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6800541-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38779189	rs6776034	T	A	rs6776034	24850809	3.02E-25	NA	11.92	[9.67-14.17] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6776034-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38779189	rs6776034	T	A	rs6776034	24850809	4.22E-20	NA	6.41	[5.04-7.78] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6776034-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38782026	rs7615140	T	C	rs7615140	24850809	2.96E-13	NA	1.59	[1.16-2.01] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7615140-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38782026	rs7615140	T	C	rs7615140	24850809	6.54E-09	NA	0.77	[0.51-1.03] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7615140-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38784029	rs6599250	T	C	rs6599250	24850809	1.47E-40	NA	2.83	[2.41-3.24] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599250-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38784029	rs6599250	T	C	rs6599250	24850809	1.90E-26	NA	1.38	[1.13-1.64] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599250-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38784957	rs7433723	G	A	rs7433723	24850809	1.79E-26	NA	1.4	[1.14-1.65] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7433723-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38784957	rs7433723	G	A	rs7433723	24850809	2.60E-40	NA	2.85	[2.43-3.27] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7433723-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38785809	rs6599251	G	T	rs6599251	24850809	6.45E-26	NA	1.37	[1.11-1.62] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599251-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	NA
3	38785809	rs6599251	G	T	rs6599251	24850809	8.46E-37	NA	2.69	[2.27-3.1] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599251-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	NA
3	38788506	rs9844265	C	T	rs9844265	24850809	2.07E-12	NA	1.78	[1.29-2.28] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9844265-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38788506	rs9844265	C	T	rs9844265	24850809	3.19E-08	NA	0.86	[0.55-1.16] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9844265-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38788728	rs9844577	C	A	rs9844577	24850809	1.89E-26	NA	1.4	[1.14-1.65] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9844577-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38789691	rs6599252	T	A	rs6599252	24850809	3.67E-09	NA	0.87	[0.58-1.16] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599252-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38795495	rs7430451	C	G	rs7430451	24850809	9.90E-13	NA	1.06	[0.77-1.35] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7430451-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38795555	rs6599254	A	G	rs6599254	24850809	3.30E-25	NA	1.37	[1.11-1.63] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599254-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38796415	rs6599255	A	C	rs6599255	24850809	1.06E-25	NA	1.4	[1.14-1.66] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599255-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38796985	rs12630795	A	G	rs12630795	24850809	1.85E-09	NA	0.86	[0.58-1.13] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12630795-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38798836	rs6798015	C	T	rs6798015	24850809	3.83E-25	NA	1.41	[1.14-1.67] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6798015-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38800747	rs6763876	T	C	rs6763876	24850809	4.88E-08	NA	0.84	[0.54-1.14] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6763876-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38801225	rs6599256	G	T	rs6599256	24850809	5.09E-10	NA	0.91	[0.62-1.2] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599256-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38802251	rs7641844	A	G	rs7641844	24850809	6.76E-10	NA	0.91	[0.62-1.19] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7641844-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38803509	rs7432804	A	G	rs7432804	24850809	8.10E-10	NA	0.9	[0.61-1.19] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7432804-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38803618	rs7430438	G	A	rs7430438	24850809	2.69E-17	NA	1.37	[1.05-1.68] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7430438-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38803639	rs7430439	G	A	rs7430439	24850809	7.67E-17	NA	1.35	[1.03-1.66] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7430439-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	38804341	rs7651106	T	C	rs7651106	24850809	9.92E-16	NA	1.24	[0.94-1.54] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7651106-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	38804588	rs6599257	C	T	rs6599257	24850809	8.93E-15	NA	1.03	[0.77-1.29] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6599257-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38806478	rs7610489	A	G	rs7610489	24850809	8.37E-15	NA	1.03	[0.77-1.29] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7610489-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	38806511	rs7650384	C	T	rs7650384	24850809	8.49E-15	NA	1.03	[0.77-1.29] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7650384-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	38812650	rs10212338	G	A	rs10212338	24850809	2.20E-14	NA	1.07	[0.79-1.34] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10212338-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	54471010	rs6768189	A	G	rs6768189	23705025	0.0000357	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	CACNA2D3
3	137447485	rs10935268	G	A	rs10935268	19578179	8.00E-07	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA	NA
3	158681562	rs7618072	C	T	rs7618072	19597491	2.40E-06	NA	NA	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	172167261	rs2922126	T	A	rs2922126	21846873	5.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
3	190265429	rs3773989	G	A	rs3773989	21846873	2.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
4	3770952	rs7678463	C	G	rs7678463	21846873	8.60E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
4	37909841	rs2925948	G	A	rs2925948	21846873	3.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
4	46985750	rs7694035	A	C	rs7694035	21846873	7.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
4	65275649	rs1384720	C	A	rs1384720	21846873	1.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
4	86642714	rs7658797	C	A	rs7658797	24850809	1.42E-14	NA	1.8	[1.35-2.26] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7658797-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
4	86651464	rs7660702	T	C	rs7660702	24850809	1.14E-14	NA	1.79	[1.33-2.24] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7660702-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	86663055	rs343849	A	T	rs343849	24850809	1.17E-14	NA	1.78	[1.33-2.23] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs343849-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	86664940	rs2601855	A	T	rs2601855	24850809	1.57E-14	NA	1.76	[1.31-2.21] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2601855-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
4	86673888	rs12507272	T	C	rs12507272	24850809	1.02E-10	NA	1.67	[1.17-2.18] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12507272-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	86674199	rs13137008	G	T	rs13137008	24850809	1.00E-14	NA	1.76	[1.32-2.21] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs13137008-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	86682968	rs13111293	C	T	rs13111293	24850809	2.55E-14	NA	1.73	[1.29-2.18] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs13111293-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	86683121	rs13111662	C	T	rs13111662	24850809	2.29E-14	NA	1.74	[1.29-2.18] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs13111662-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	86685746	rs7674888	G	A	rs7674888	24850809	3.41E-08	NA	1.58	[1.02-2.14] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7674888-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	86688769	rs12054628	T	A	rs12054628	24850809	3.12E-08	NA	1.58	[1.02-2.14] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12054628-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	86692665	rs6831420	G	A	rs6831420	24850809	3.51E-08	NA	1.55	[1-2.1] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6831420-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	86702112	rs17395020	A	T	rs17395020	24850809	2.66E-08	NA	1.85	[1.2-2.5] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs17395020-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
4	86702170	rs17399123	C	T	rs17399123	24850809	3.23E-08	NA	1.81	[1.17-2.46] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs17399123-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	86714299	rs958800	C	T	rs958800	19597491	2.00E-06	NA	NA	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	111552398	rs994978	T	C	rs994978	21846873	1.20E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
4	111629039	rs16997168	C	T	rs16997168	19597491	1.30E-07	NA	NA	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	111634287	rs2723316	T	C	rs2723316	19597491	5.90E-08	NA	NA	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	111641053	rs1448817	A	G	rs1448817	19597491	1.60E-10	NA	NA	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	111665783	rs2634073	T	C	rs2634073	19597491	1.40E-14	NA	NA	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
4	111705768	rs6817105	T	C	rs6817105	22544366	2.00E-74	NA	1.64	[1.55-1.73]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs6817105-C	Meta-Analysis	C	NA
4	111708287	rs17042171	C	A	rs17042171	19597492	4.00E-63	NA	1.65	NA	3,413 cases; 37,105 referents	NOPOP(40518)	ALL(40518)	NOPOP(40518)	ALL(40518)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs17042171-A	NA	C	NA
4	111710169	rs2200733	C	T	rs2200733	19597491	1.00E-14	NA	1.42	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	111710169	rs2200733	C	T	rs2200733	21846873	2.50E-16	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
4	111711041	rs4611994	T	C	rs4611994	21846873	2.60E-16	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
4	111714889	rs2220427	C	T	rs2220427	19597491	1.40E-14	NA	NA	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	111718067	rs6843082	G	A	rs6843082	20173747	3.00E-28	NA	2.03	[1.79-2.30]	1,335 European descent cases; 12,844 European descent controls	European(14179)	ALL(14179)	EUR(14179)	ALL(14179)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs6843082-G	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	111728614	rs13141190	A	G	rs13141190	19597491	2.30E-14	NA	NA	NA	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	155532639	rs2066867	A	G	rs2066867	21846873	2.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
5	79965536	rs6151627	A	G	rs6151627	21846873	8.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
5	89979485	rs35791889	C	G,T	rs35791889	21846873	4.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
5	137419989	rs2040862	C	T	rs2040862	22544366	3.00E-07	NA	1.12	[1.07-1.17]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs2040862-T	Meta-Analysis	C	WNT8A
5	158750329	rs3213096	C	T	rs3213096	21846873	2.00E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
5	172664163	rs6882776	G	A	rs6882776	23583979	4.41E-08	NA	1.11	[1.07-1.15] unit increase	85,787 European ancestry individuals; 6,568 Indian Asian ancestry indiviudals	European(85787)	Indian Asian(6568)	ALL(92355)	EUR(85787)	SAN(6568)	ALL(92355)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs6882776-G	Meta-Analysis
6	36647289	rs3176326	G	A	rs3176326	21846873	3.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
6	118667522	rs11153730	T	C	rs11153730	23583979	5.19E-04	NA	1.06	[1.03-1.10] unit increase	85,787 European ancestry individuals; 6,568 Indian Asian ancestry indiviudals	European(85787)	Indian Asian(6568)	ALL(92355)	EUR(85787)	SAN(6568)	ALL(92355)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs11153730-T	Meta-Analysis
6	122131485	rs1015451	T	C	rs1015451	23583979	1.58E-04	NA	0.9	[0.86-0.95] unit increase	85,787 European ancestry individuals; 6,568 Indian Asian ancestry indiviudals	European(85787)	Indian Asian(6568)	ALL(92355)	EUR(85787)	SAN(6568)	ALL(92355)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs1015451-C	Meta-Analysis
6	130469126	rs2152192	T	C	rs2152192	23705025	0.0000277	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	SAMD3
6	148324907	rs9322115	A	T	rs9322115	25015694	4.66E-05	NA	1.91	[1.40-2.61]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9322115-A	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148333960	rs1358689	C	T	rs1358689	25015694	2.19E-05	NA	2.33	[1.59-3.45]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1358689-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148334316	rs9386204	G	A	rs9386204	25015694	2.10E-05	NA	2.33	[1.59-3.45]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9386204-G	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148338905	rs7765323	C	G	rs7765323	25015694	3.67E-05	NA	1.84	[1.38-2.46]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7765323-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148340111	rs1406710	A	T	rs1406710	25015694	4.05E-05	NA	1.85	[1.38-2.49]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1406710-A	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148340146	rs1406709	T	A	rs1406709	25015694	3.94E-05	NA	1.85	[1.39-2.50]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1406709-T	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148340422	rs4896955	C	T	rs4896955	25015694	6.04E-05	NA	1.82	[1.35-2.44]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4896955-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148340812	rs9403913	G	T	rs9403913	25015694	4.28E-05	NA	1.82	[1.37-2.44]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9403913-G	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148340955	rs9403915	C	T	rs9403915	25015694	4.21E-05	NA	1.82	[1.37-2.44]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9403915-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148341115	rs9377097	G	A	rs9377097	25015694	3.03E-05	NA	2.27	[1.56-3.45]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9377097-G	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148341674	rs1881827	G	A	rs1881827	25015694	3.11E-05	NA	2.27	[1.56-3.33]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1881827-G	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148343053	rs9403916	C	T	rs9403916	25015694	3.96E-05	NA	1.85	[1.37-2.44]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9403916-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148344667	rs4896956	T	G	rs4896956	25015694	3.57E-05	NA	1.85	[1.38-2.47]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4896956-T	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148344769	rs4896957	C	T	rs4896957	25015694	3.96E-05	NA	1.85	[1.37-2.44]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4896957-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148344804	rs4896958	C	T	rs4896958	25015694	3.90E-05	NA	1.85	[1.37-2.44]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4896958-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148346318	rs9322117	C	A	rs9322117	25015694	3.01E-05	NA	1.85	[1.39-2.50]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9322117-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148346323	rs9322118	C	T	rs9322118	25015694	3.02E-05	NA	1.85	[1.39-2.50]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9322118-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148346615	rs1534773	C	T	rs1534773	25015694	1.69E-05	NA	1.89	[1.41-2.56]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1534773-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148350314	rs2328840	C	A	rs2328840	25015694	2.58E-05	NA	2.33	[1.56-3.45]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2328840-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148351816	rs9390526	C	T	rs9390526	25015694	2.83E-05	NA	2.33	[1.56-3.45]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9390526-C	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148355552	rs1534774	G	C	rs1534774	25015694	1.67E-05	NA	2.38	[1.61-3.57]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1534774-G	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148358891	rs1997380	T	C	rs1997380	25015694	3.30E-05	NA	1.88	[1.39-2.53]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1997380-T	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148360063	rs1404488	A	G	rs1404488	25015694	3.53E-05	NA	2.3	[1.55-3.41]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1404488-A	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148369104	rs2876678	A	G	rs2876678	25015694	7.15E-05	NA	1.81	[1.35-2.42]	95 non-responders; 190 responders	NOPOP(285)	ALL(285)	NOPOP(285)	ALL(285)	Response to rate control therapy in atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2876678-A	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	170512479	rs13193455	G	A	rs13193455	23705025	0.0000295	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA
7	10146577	rs7798735	C	T	rs7798735	21846873	5.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
7	38262723	rs756392	C	T	rs756392	21846873	3.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
7	51795300	rs1860867	G	A	rs1860867	23705025	0.0000141	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA
7	72877166	rs2074755	T	C	rs2074755	21846873	5.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
7	116186241	rs3807989	A	G	rs3807989	22544366	4.00E-12	NA	1.11	[1.09-1.15]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs3807989-G	Meta-Analysis	A	CAV1
7	116186241	rs3807989	A	G	rs3807989	24850809	5.00E-12	NA	1.4	[1.00-1.79] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3807989-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	116191301	rs11773845	C	A	rs11773845	24850809	4.33E-11	NA	1.48	[1.04-1.92] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11773845-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	116198828	rs1997572	A	G	rs1997572	24850809	1.51E-11	NA	1.4	[1-1.81] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1997572-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	116200587	rs1049337	C	T	rs1049337	24850809	8.30E-11	NA	3.03	[2.12-3.95] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1049337-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	116206665	rs2052106	A	G	rs2052106	24850809	8.08E-10	NA	1.42	[0.96-1.87] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2052106-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	125805301	rs683493	G	A	rs683493	21846873	6.90E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
7	132094453	rs2341825	C	A	rs2341825	21846873	5.60E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	6829085	rs2738113	G	T	rs2738113	21846873	3.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	31504639	rs4733267	C	T	rs4733267	21846873	1.98E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	31633553	rs10503888	T	C	rs10503888	21846873	7.70E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	31635834	rs16878272	G	C	rs16878272	21846873	2.06E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	31753921	rs17680540	G	C	rs17680540	21846873	2.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	31770158	rs756266	T	C	rs756266	21846873	1.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	31965188	rs6993043	T	C	rs6993043	21846873	8.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	37824817	rs35361594	C	T	rs35361594	21846873	5.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	42140549	rs5029748	G	T	rs5029748	21846873	8.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	67070155	rs7843038	C	T	rs7843038	21846873	8.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	67970243	rs6997490	A	G	rs6997490	21846873	3.60E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	68574359	rs10112728	A	G	rs10112728	21846873	6.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	73927124	rs16938550	G	A	rs16938550	21846873	7.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	100180871	rs4442113	A	G	rs4442113	21846873	2.70E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	100432976	rs3103705	C	T	rs3103705	21846873	8.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
8	121062077	rs1051534	A	G	rs1051534	21846873	8.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
9	22098619	rs2891168	A	G	rs2891168	21846873	5.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
9	78782943	rs10869717	A	G	rs10869717	21846873	7.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
9	97713459	rs10821415	C	A	rs10821415	22544366	4.00E-11	NA	1.11	[1.08-1.15]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs10821415-A	Meta-Analysis	C	C9orf3
9	113665254	rs1409684	C	T	rs1409684	21846873	7.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
9	123676699	rs758959	C	T	rs758959	21846873	2.60E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
10	75421208	rs10824026	G	A	rs10824026	22544366	4.00E-09	NA	1.15	[1.10-1.20]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs10824026-A	Meta-Analysis	G	NA
10	80622356	rs570677	C	T	rs570677	21846873	7.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
10	91004886	rs2246942	A	G	rs2246942	21846873	5.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
10	96405329	rs12772169	C	T	rs12772169	19578179	8.00E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	NA	NA	NA
10	96407978	rs1998591	G	A	rs1998591	19578179	8.06E-09	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C,T	NA	NA
10	96429971	rs2104543	C	T	rs2104543	19578179	1.09E-08	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	NA	NA
10	96464730	rs7896133	G	A	rs7896133	19578179	8.19E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	CYP2C18	intron
10	96547463	rs12767583	C	T	rs12767583	19578179	3.00E-07	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	CYP2C19	intron
10	96576190	rs10509678	A	C	rs10509678	19578179	5.02E-11	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	NA	CYP2C19	intron
10	96619025	rs3862009	C	T	rs3862009	19578179	1.31E-11	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	NA	NA
10	96619086	rs733115	G	T	rs733115	19578179	1.31E-11	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA	NA
10	96700537	rs2253635	C	T	rs2253635	19578179	3.19E-09	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	CYP2C9	intron
10	96707202	rs4086116	C	T	rs4086116	19578179	3.29E-24	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	CYP2C9	intron
10	96711884	rs4918766	G	A	rs4918766	19578179	1.82E-21	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	CYP2C9	intron
10	96725535	rs4917639	A	C	rs4917639	19578179	8.02E-24	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	CYP2C9	intron
10	96731310	rs9332169	A	G	rs9332169	19578179	8.34E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	CYP2C9	intron
10	96734339	rs10509680	G	T	rs10509680	19578179	8.34E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	CYP2C9	intron
10	96741053	rs1057910	A	C	rs1057910	19578179	6.44E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	CYP2C9	missense
10	96743108	rs9332214	T	C	rs9332214	19578179	8.34E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	CYP2C9	intron
10	96751270	rs2185570	T	C	rs2185570	19578179	4.72E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	NA	NA
10	96797571	rs11572174	G	A	rs11572174	19578179	7.89E-09	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	CYP2C8	intron
10	96798749	rs10509681	T	C	rs10509681	19578179	8.60E-09	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	CYP2C8	missense
10	102385066	rs2489020	T	C	rs2489020	21846873	6.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
10	108416572	rs1252031	C	T	rs1252031	21846873	3.50E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
11	2763228	rs7114479	T	C	rs7114479	21846873	6.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
11	2781670	rs463535	T	C	rs463535	21846873	5.36E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
11	6459938	rs4758417	A	G	rs4758417	21846873	1.44E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
11	17351683	rs757081	C	G	rs757081	21846873	8.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
11	61543499	rs174528	T	C	rs174528	24850809	3.16E-08	NA	0.9	[0.58-1.21] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs174528-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
11	61600342	rs174574	A	C	rs174574	24850809	3.40E-08	NA	0.73	[0.47-0.99] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs174574-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	61603510	rs174576	C	A	rs174576	24850809	3.29E-08	NA	0.73	[0.47-0.99] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs174576-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	61604814	rs174577	C	A	rs174577	24850809	3.00E-08	NA	0.74	[0.48-0.99] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs174577-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	61605499	rs174578	T	A	rs174578	24850809	2.69E-08	NA	0.73	[0.48-0.99] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	P wave duration	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs174578-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	76596504	rs618076	G	T	rs618076	21846873	4.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
11	99493173	rs10501920	C	G	rs10501920	17903304	9.00E-06	NA	NA	NA	1,345 individuals depending on measure (Framingham)	Framingham(1345)	ALL(1345)	EUR(1345)	ALL(1345)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	C	CNTN5
11	113286878	rs2440390	T	C	rs2440390	21846873	5.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
11	113307129	rs4586205	G	T	rs4586205	21846873	4.50E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
11	113316236	rs12574471	C	T	rs12574471	21846873	3.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
12	5149184	rs7961013	A	G	rs7961013	21846873	2.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
12	24770878	rs17287293	A	G	rs17287293	23583979	2.38E-07	NA	1.13	[1.08-1.19] unit increase	85,787 European ancestry individuals; 6,568 Indian Asian ancestry indiviudals	European(85787)	Indian Asian(6568)	ALL(92355)	EUR(85787)	SAN(6568)	ALL(92355)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs17287293-A	Meta-Analysis
12	24788339	rs11047543	G	A	rs11047543	22544366	3.50E-07	NA	NA	NA	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Meta-Analysis	G	NA
12	26297832	rs748775	C	T	rs748775	21846873	3.50E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
12	46619130	rs10880942	T	C	rs10880942	23705025	0.00000044	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	SLC38A1
12	71937646	rs941197	A	G	rs941197	21846873	3.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
12	109888779	rs1477117	G	A	rs1477117	21846873	3.70E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
12	114795443	rs3825214	G	A	rs3825214	22544366	4.10E-07	NA	NA	NA	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Meta-Analysis	A	TBX5
12	115157609	rs10850369	T	G	rs10850369	24850809	2.86E-08	NA	1.53	[0.99-2.07] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10850369-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115344085	rs4625524	G	A	rs4625524	24850809	7.28E-09	NA	1.61	[1.06-2.15] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4625524-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115344782	rs1955105	T	G	rs1955105	24850809	2.61E-09	NA	1.29	[0.87-1.72] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1955105-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115346424	rs1896312	C	T	rs1896312	24850809	1.17E-09	NA	1.6	[1.09-2.12] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1896312-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115349497	rs1124477	T	C	rs1124477	24850809	5.83E-10	NA	1.39	[0.95-1.83] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1124477-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	115354179	rs4766748	C	T	rs4766748	24850809	1.14E-09	NA	1.55	[1.05-2.04] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4766748-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	115357003	rs1896330	G	A	rs1896330	24850809	5.98E-10	NA	1.45	[0.99-1.9] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1896330-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115357432	rs1896329	C	T	rs1896329	24850809	6.57E-10	NA	1.56	[1.06-2.05] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1896329-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	115357928	rs2384552	A	G	rs2384552	24850809	5.49E-10	NA	1.56	[1.07-2.05] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2384552-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115358952	rs2891537	T	G	rs2891537	24850809	5.51E-10	NA	1.54	[1.05-2.03] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2891537-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	115359206	rs7967168	T	A	rs7967168	24850809	2.32E-10	NA	1.5	[1.03-1.96] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7967168-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115360824	rs7132580	G	A	rs7132580	24850809	7.82E-10	NA	1.45	[0.99-1.91] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7132580-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115360866	rs7132593	G	A	rs7132593	24850809	7.13E-10	NA	1.46	[0.99-1.92] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7132593-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115361364	rs6416327	T	G	rs6416327	24850809	1.23E-10	NA	1.53	[1.06-2] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs6416327-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	115362278	rs2384554	T	G	rs2384554	24850809	1.61E-09	NA	1.41	[0.95-1.86] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2384554-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115362584	rs7979724	T	C	rs7979724	24850809	1.93E-09	NA	1.4	[0.94-1.86] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7979724-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115362972	rs7977151	A	G	rs7977151	24850809	6.64E-11	NA	1.54	[1.08-2] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7977151-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115363111	rs7980361	T	C	rs7980361	24850809	7.65E-10	NA	1.46	[0.99-1.92] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7980361-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115363443	rs11067327	C	T	rs11067327	24850809	6.01E-11	NA	1.53	[1.07-1.99] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11067327-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	115363751	rs3914956	T	A	rs3914956	24850809	9.15E-10	NA	1.45	[0.99-1.92] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3914956-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115365211	rs7966951	A	G	rs7966951	24850809	9.80E-12	NA	1.61	[1.15-2.07] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7966951-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	115371208	rs7311039	G	C	rs7311039	24850809	1.74E-09	NA	1.43	[0.96-1.89] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7311039-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	115371742	rs10744836	T	G	rs10744836	24850809	5.40E-09	NA	1.36	[0.9-1.82] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10744836-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115371958	rs7966651	T	C	rs7966651	24850809	1.56E-09	NA	1.43	[0.96-1.89] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7966651-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	115381071	rs7132327	T	C	rs7132327	24850809	7.98E-13	NA	1.63	[1.18-2.07] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs7132327-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115381740	rs10850409	G	A	rs10850409	24850809	8.00E-13	NA	1.65	[1.20-2.10] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10850409-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	115383743	rs4994122	G	C	rs4994122	24850809	2.59E-10	NA	2.72	[1.87-3.56] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4994122-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	115387033	rs11611538	C	A	rs11611538	24850809	1.83E-08	NA	2.03	[1.32-2.73] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11611538-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	115387968	rs10850412	T	C	rs10850412	24850809	2.34E-08	NA	2.03	[1.32-2.74] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10850412-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	115389126	rs10744840	G	A	rs10744840	24850809	1.32E-08	NA	2.07	[1.35-2.78] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10744840-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	115394076	rs10850414	C	A	rs10850414	24850809	3.91E-08	NA	2.02	[1.3-2.74] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10850414-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	115413953	rs11611866	A	G	rs11611866	24850809	7.09E-09	NA	2.12	[1.4-2.84] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11611866-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	115423129	rs10850421	A	G	rs10850421	24850809	8.43E-09	NA	2.31	[1.52-3.1] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10850421-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
13	21300909	rs2253017	C	T	rs2253017	24850809	2.00E-08	NA	1.58	[1.03-2.13] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2253017-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	21348279	rs3936081	A	C,G	rs3936081	24850809	2.77E-08	NA	1.98	[1.28-2.67] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs3936081-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22076491	rs2315545	C	T	rs2315545	24850809	2.62E-09	NA	1.29	[0.86-1.71] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2315545-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22085659	rs718426	A	G	rs718426	24850809	2.84E-09	NA	1.25	[0.84-1.66] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs718426-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22090066	rs1044090	A	C	rs1044090	24850809	2.08E-09	NA	1.24	[0.84-1.65] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1044090-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22092762	rs12861578	T	G	rs12861578	24850809	1.75E-09	NA	1.25	[0.84-1.65] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12861578-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22092961	rs4770170	T	C	rs4770170	24850809	1.84E-09	NA	1.25	[0.84-1.66] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4770170-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22096611	rs1359190	T	G	rs1359190	24850809	2.03E-09	NA	1.23	[0.83-1.64] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1359190-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22102976	rs10492455	A	G	rs10492455	24850809	1.06E-09	NA	1.26	[0.85-1.66] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10492455-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22103294	rs12869776	A	G	rs12869776	24850809	1.05E-09	NA	1.26	[0.85-1.66] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12869776-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22106134	rs2798264	A	T	rs2798264	24850809	2.31E-09	NA	1.45	[0.97-1.92] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2798264-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22111521	rs11841562	C	A	rs11841562	24850809	1.71E-09	NA	1.29	[0.87-1.71] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11841562-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22112853	rs2798280	T	C	rs2798280	24850809	1.96E-09	NA	1.26	[0.85-1.67] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2798280-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22115822	rs11616720	A	G	rs11616720	24850809	7.82E-10	NA	1.3	[0.89-1.71] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11616720-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22116804	rs2761909	T	C	rs2761909	24850809	2.82E-09	NA	1.7	[1.14-2.26] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2761909-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22117071	rs1539562	A	G	rs1539562	24850809	8.90E-10	NA	1.28	[0.87-1.69] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1539562-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22120666	rs12584577	C	T	rs12584577	24850809	4.08E-10	NA	1.37	[0.94-1.8] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12584577-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22122477	rs17679426	A	T	rs17679426	24850809	4.05E-10	NA	1.37	[0.94-1.8] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs17679426-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22123676	rs4770172	A	G	rs4770172	24850809	3.40E-10	NA	1.38	[0.95-1.81] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4770172-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22124028	rs12877509	G	C	rs12877509	24850809	1.25E-09	NA	1.27	[0.86-1.68] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12877509-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22131160	rs1200046	C	A	rs1200046	24850809	1.18E-09	NA	1.27	[0.86-1.68] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1200046-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22131801	rs2761911	T	G	rs2761911	24850809	1.23E-09	NA	1.27	[0.86-1.68] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2761911-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22131897	rs2798269	C	T	rs2798269	24850809	3.00E-10	NA	1.38	[0.95-1.81] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2798269-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22134037	rs2761912	C	T	rs2761912	24850809	4.58E-10	NA	1.37	[0.94-1.8] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2761912-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22135042	rs2761913	C	T	rs2761913	24850809	4.58E-10	NA	1.37	[0.94-1.8] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2761913-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22136766	rs2798272	C	G	rs2798272	24850809	3.84E-10	NA	1.38	[0.95-1.81] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2798272-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22137130	rs2761914	T	A	rs2761914	24850809	1.44E-09	NA	1.28	[0.86-1.69] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2761914-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22137266	rs2476639	T	G	rs2476639	24850809	1.46E-09	NA	1.27	[0.86-1.69] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2476639-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22137608	rs11148157	A	T	rs11148157	24850809	4.40E-10	NA	1.38	[0.94-1.81] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11148157-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22137743	rs11148158	C	T	rs11148158	24850809	4.54E-10	NA	1.38	[0.94-1.81] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11148158-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22138384	rs2093804	T	G	rs2093804	24850809	1.61E-09	NA	1.27	[0.86-1.68] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2093804-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22138691	rs4770174	T	C	rs4770174	24850809	1.70E-09	NA	1.27	[0.86-1.68] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4770174-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22141526	rs11148159	T	A	rs11148159	24850809	2.11E-09	NA	1.31	[0.88-1.74] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11148159-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	22141587	rs2249901	C	G	rs2249901	24850809	2.63E-09	NA	1.43	[0.96-1.9] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2249901-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22143100	rs2040059	C	G	rs2040059	24850809	4.08E-10	NA	1.38	[0.95-1.81] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2040059-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
13	22145941	rs12429479	C	T	rs12429479	24850809	4.21E-10	NA	1.39	[0.95-1.82] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12429479-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22146413	rs12430739	A	T	rs12430739	24850809	5.61E-10	NA	1.39	[0.95-1.84] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs12430739-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22150209	rs10870842	A	C	rs10870842	24850809	4.40E-10	NA	1.39	[0.96-1.83] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs10870842-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22155781	rs2798277	G	C	rs2798277	24850809	3.89E-09	NA	1.34	[0.89-1.78] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2798277-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
13	22159035	rs2798275	T	A	rs2798275	24850809	3.45E-09	NA	1.35	[0.9-1.8] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs2798275-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	22165262	rs1200034	T	C	rs1200034	24850809	4.11E-09	NA	1.39	[0.93-1.86] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs1200034-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22170275	rs11148172	C	T	rs11148172	24850809	4.34E-10	NA	1.56	[1.07-2.05] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs11148172-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	22179186	rs4770182	T	G	rs4770182	24850809	1.68E-08	NA	1.47	[0.96-1.98] unit increase	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs4770182-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	41138389	rs2701858	C	T	rs2701858	21846873	9.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
13	46833717	rs958546	G	C	rs958546	17903304	5.00E-06	NA	NA	NA	1,345 individuals depending on measure (Framingham)	Framingham(1345)	ALL(1345)	EUR(1345)	ALL(1345)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	C	LRRC63
13	47237952	rs9534458	G	A	rs9534458	24850809	3.00E-08	NA	1.18	[0.76-1.59] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9534458-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
13	47238717	rs9590974	C	A	rs9590974	24850809	2.00E-08	NA	1.19	[0.78-1.61] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9590974-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	47238950	rs9534459	T	A	rs9534459	24850809	2.13E-08	NA	1.19	[0.77-1.6] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs9534459-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	47239853	rs8001925	G	A	rs8001925	24850809	2.67E-08	NA	1.16	[0.75-1.57] unit decrease	16,468 European ancestry individuals	European(16468)	ALL(16468)	EUR(16468)	ALL(16468)	PR segment	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	NA	NA	NA	NA	Cardiovascular disease	rs8001925-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	110822524	rs12868126	G	A	rs12868126	21846873	8.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
14	51828412	rs2356895	C	T	rs2356895	23705025	0.00000128	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	LOC283553
14	55355031	rs998259	C	T	rs998259	21846873	3.59E-06	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
14	55643752	rs8009244	A	G	rs8009244	21846873	2.70E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
14	61806908	rs2025526	G	A	rs2025526	21846873	8.90E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
14	62000170	rs12587495	A	G	rs12587495	21846873	4.36E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
14	62206548	rs2301113	C	A	rs2301113	21846873	6.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
14	64680848	rs1152591	A	G	rs1152591	22544366	6.00E-13	NA	1.13	[1.09-1.17]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs1152591-A	Meta-Analysis	C	SYNE2
14	94763493	rs4900224	T	C	rs4900224	21846873	8.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
14	94835647	rs3748319	C	T	rs3748319	21846873	4.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
15	70006873	rs4776472	G	A	rs4776472	17903304	8.00E-06	NA	NA	NA	1,345 individuals depending on measure (Framingham)	Framingham(1345)	ALL(1345)	EUR(1345)	ALL(1345)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural	G	NA
15	73652174	rs7164883	A	G	rs7164883	22544366	3.00E-17	NA	1.19	[1.14-1.24]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs7164883-G	Meta-Analysis	A	HCN4
15	73665506	rs4489968	T	G	rs4489968	23583979	1.85E-12	NA	0.86	[0.82-0.89] unit increase	85,787 European ancestry individuals; 6,568 Indian Asian ancestry indiviudals	European(85787)	Indian Asian(6568)	ALL(92355)	EUR(85787)	SAN(6568)	ALL(92355)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs4489968-T	Meta-Analysis
15	85544887	rs11856097	G	A	rs11856097	21846873	8.90E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
15	101997586	rs4246336	A	G	rs4246336	21846873	3.80E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
16	20599486	rs11643396	G	A	rs11643396	21846873	1.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
16	20680152	rs16970500	T	G	rs16970500	21846873	6.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
16	30520856	rs17790434	C	T	rs17790434	19578179	9.21E-11	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	ITGAL	intron
16	30539097	rs11645241	C	T	rs11645241	19578179	3.07E-16	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	NA	NA
16	30546488	rs6565191	G	A	rs6565191	19578179	8.96E-28	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA	NA
16	30642867	rs7197475	C	T	rs7197475	19578179	9.32E-20	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	NA	NA
16	30666367	rs3747481	C	T	rs3747481	19578179	1.42E-11	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	PRR14	missense
16	30726248	rs8058578	C	T	rs8058578	19578179	3.93E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	SRCAP	intron
16	30781942	rs11642466	A	G	rs11642466	19578179	5.60E-14	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	RNF40	intron
16	30809063	rs8058961	G	A	rs8058961	19578179	9.03E-14	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA	NA
16	30823047	rs4889490	G	T	rs4889490	19578179	2.33E-63	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA	NA
16	30833321	rs8046001	C	T	rs8046001	19578179	7.40E-33	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	NA	NA
16	30850242	rs11150596	C	T	rs11150596	19578179	1.81E-35	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	NA	NA
16	30903679	rs9933843	C	T	rs9933843	19578179	2.58E-47	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	BCL7C	intron
16	30928970	rs12924903	A	G	rs12924903	19578179	2.50E-40	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA	NA
16	30947572	rs7200879	A	G	rs7200879	19578179	5.00E-19	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	FBXL19	intron
16	30970741	rs2305884	G	A	rs2305884	19578179	2.47E-42	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	SETD1A	intron
16	30980902	rs897986	T	C	rs897986	19578179	1.43E-43	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	SETD1A	intron
16	31004812	rs12445568	T	C	rs12445568	19578179	3.53E-47	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	STX1B	intron
16	31048079	rs10871454	C	T	rs10871454	19578179	2.00E-123	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	STX4	intron
16	31102321	rs7294	C	T	rs7294	19578179	1.40E-45	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	VKORC1	UTR-3
16	31122571	rs889555	C	T	rs889555	19578179	6.56E-17	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	BCKDK	intron
16	31124407	rs749767	A	G	rs749767	19578179	3.08E-103	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	NA	NA
16	31129942	rs1978487	C	T	rs1978487	19578179	7.82E-104	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	KAT8	intron
16	31132250	rs11865499	A	G	rs11865499	19578179	1.44E-17	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	KAT8	intron
16	31137712	rs889548	C	T	rs889548	19578179	5.61E-106	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	KAT8	intron
16	31193942	rs741810	C	A	rs741810	19578179	4.68E-19	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	FUS	cds-synon
16	31214898	rs8056505	C	T	rs8056505	19578179	2.49E-19	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	PYCARD	nearGene-5
16	31264267	rs4889640	C	A	rs4889640	19578179	3.33E-17	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	NA	NA
16	31279536	rs8048583	T	C	rs8048583	19578179	6.26E-17	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	ITGAM	intron
16	31289396	rs1143680	T	C	rs11861251	19578179	1.01E-08	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	ITGAM	missense
16	31334236	rs11150610	C	A	rs11150610	19578179	3.72E-28	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	ITGAM	intron
16	31347748	rs3925075	A	G	rs3925075	19578179	1.68E-12	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	NA	NA
16	31357760	rs11150612	G	A	rs11150612	19578179	8.19E-24	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA	NA
16	31363977	rs11574631	C	T	rs11574631	19578179	2.55E-15	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	T	NA	NA
16	31366016	rs11150614	A	G	rs11150614	19578179	6.92E-15	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	ITGAX	nearGene-5
16	73029160	rs7193343	T	C	rs7193343	19597491	1.00E-10	NA	1.21	[1.14-1.29]	2,385 European ancestry cases; 33,752 European ancestry controls	European(36137)	ALL(36137)	EUR(36137)	ALL(36137)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs7193343-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
16	73051620	rs2106261	C	T	rs2106261	19597492	2.00E-15	NA	1.25	NA	3,413 cases; 37,105 referents	NOPOP(40518)	ALL(40518)	NOPOP(40518)	ALL(40518)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs2106261-T	NA	G	ZFHX3
16	73051620	rs2106261	C	T	rs2106261	22544366	3.00E-16	NA	1.24	[1.17-1.30]	6,707 European ancestry cases; 52,426 European ancestry controls	European(59133)	ALL(59133)	EUR(59133)	ALL(59133)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	rs2106261-T	Meta-Analysis	G	ZFHX3
17	7187793	rs5436	C	T	rs5436	21846873	3.16E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
17	10082169	rs4128645	C	T	rs4128645	21846873	5.60E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
17	12635215	rs758185	C	G	rs758185	21846873	4.70E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
17	39838104	rs12453963	T	C	rs12453963	21846873	3.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
17	74149689	rs1868821	C	T	rs1868821	21846873	4.10E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
17	80255037	rs9896932	A	G	rs9896932	23705025	0.0000191	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	NA
18	60816836	rs12457170	G	A	rs12457170	21846873	3.40E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
19	850574	rs3761007	G	A	rs3761007	21846873	4.30E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
19	1691725	rs10405317	T	G	rs10405317	21846873	8.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
19	15990431	rs2108622	C	T	rs2108622	19578179	3.00E-10	NA	NA	NA	1,451 European ancestry individuals	European(1451)	ALL(1451)	EUR(1451)	ALL(1451)	Acenocoumarol maintenance dosage	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	D000074	Acenocoumarol	response to anticoagulant	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	C	CYP4F2	missense
19	30067853	rs2288895	A	G	rs2288895	21846873	7.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
19	40450048	rs2231738	T	C	rs2231738	21846873	6.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
19	45448884	rs12709885	A	T	rs12709885	21846873	2.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
19	54317914	rs3888090	T	C	rs3888090	21846873	3.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
19	54317933	rs3848584	T	C	rs3848584	21846873	3.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
20	36969972	rs11086556	A	G	rs11086556	21846873	2.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
20	45359408	rs998422	A	G	rs998422	21846873	5.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
20	45361455	rs3091904	T	C	rs3091904	21846873	9.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
20	46425576	rs13038095	G	T	rs13038095	20173747	2.00E-07	NA	1.47	[1.39-1.54]	1,335 European descent cases; 12,844 European descent controls	European(14179)	ALL(14179)	EUR(14179)	ALL(14179)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Multicenter Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
21	36277558	rs9985174	T	A	rs9985174	21846873	7.90E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	18601415	rs361540	A	G	rs361540	21846873	2.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	18610110	rs362249	A	G	rs362249	21846873	1.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	18611223	rs361557	A	G	rs361557	21846873	1.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	22190163	rs17759796	C	A	rs17759796	21846873	1.30E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	24464377	rs3827321	A	G	rs3827321	21846873	8.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	24893336	rs3788371	A	G	rs3788371	21846873	5.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	31113433	rs7285562	G	A	rs7285562	21846873	2.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	31156296	rs5749162	G	A	rs5749162	21846873	9.50E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	31254954	rs5997787	T	C	rs5997787	21846873	3.60E-05	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	31255029	rs5997788	G	T	rs5997788	21846873	3.30E-06	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
22	33950513	rs762057	G	A	rs762057	23705025	0.0000944	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	G	LARGE
22	33956080	rs713703	T	C	rs713703	23705025	0.0000313	NA	NA	NA	353 Spanish individuals in 21 extended families	Spanish(353)	ALL(353)	EUR(353)	ALL(353)	Antithrombin	HPOID:0005110	Atrial fibrillation	DOID:1247	blood coagulation disease	NA	NA	NA	NA	Hematopoietic system disease	NA	Research Support, Non-U.S. Gov't	A	LARGE
22	51023340	rs6009932	A	G	rs6009932	21846873	1.00E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural
X	100604652	rs1122765	C	A	rs1122765	21846873	1.20E-04	Atrial fibrillation	NA	NA	2260 European ancestry cases; 16264 European ancestry controls; 263 African ancestry cases; 3399 African ancestry controls	African(3662)	European(18524)	ALL(22186)	AFR(3662)	EUR(18524)	ALL(22186)	Atrial fibrillation	HPOID:0005110	Atrial fibrillation	DOID:0050650	familial atrial fibrillation	D001281	Atrial Fibrillation	EFOID:0000275	atrial fibrillation	Cardiovascular disease	NA	Research Support, N.I.H., Extramural

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:55)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0004238	acetaminophen	D000082	103-90-2	atrial fibrillation	MESH:D001281	marker/mechanism	11599527
C0004238	adenosine triphosphate	D000255	56-65-5	atrial fibrillation	MESH:D001281	marker/mechanism	20938414
C0004238	alprazolam	D000525	28981-97-7	atrial fibrillation	MESH:D001281	marker/mechanism	10389047
C0004238	arsenic trioxide	C006632	1327-53-3	atrial fibrillation	MESH:D001281	marker/mechanism	18463343
C0004238	atenolol	D001262	29122-68-7	atrial fibrillation	MESH:D001281	marker/mechanism	7106148
C0004238	atropine	D001285	51-55-8	atrial fibrillation	MESH:D001281	marker/mechanism	17073912
C0004238	atropine	D001285	51-55-8	atrial fibrillation	MESH:D001281	therapeutic	11282081
C0004238	benazepril	C044946	86541-75-5	atrial fibrillation	MESH:D001281	therapeutic	21545815
C0004238	bisoprolol	D017298	66722-44-9	atrial fibrillation	MESH:D001281	therapeutic	21129714
C0004238	caffeine	D002110	1958/8/2	atrial fibrillation	MESH:D001281	marker/mechanism	6835272
C0004238	carbachol	D002217	-	atrial fibrillation	MESH:D001281	marker/mechanism	4397202
C0004238	chlorpromazine	D002746	50-53-3	atrial fibrillation	MESH:D001281	marker/mechanism	5633497
C0004238	cimetidine	D002927	51481-61-9	atrial fibrillation	MESH:D001281	marker/mechanism	6712387
C0004238	ciprofloxacin	D002939	85721-33-1	atrial fibrillation	MESH:D001281	marker/mechanism	17669094
C0004238	citalopram	D015283	59729-33-8	atrial fibrillation	MESH:D001281	marker/mechanism	12503252
C0004238	creatine	D003401	57-00-1	atrial fibrillation	MESH:D001281	marker/mechanism	15899738
C0004238	cyclophosphamide	D003520	50-18-0	atrial fibrillation	MESH:D001281	marker/mechanism	16247745
C0004238	cisplatin	D002945	15663-27-1	atrial fibrillation	MESH:D001281	marker/mechanism	3187073
C0004238	digoxin	D004077	20830-75-5	atrial fibrillation	MESH:D001281	marker/mechanism	11761419
C0004238	digoxin	D004077	20830-75-5	atrial fibrillation	MESH:D001281	therapeutic	10689846
C0004238	diltiazem	D004110	42399-41-7	atrial fibrillation	MESH:D001281	therapeutic	12681894
C0004238	disopyramide	D004206	3737/9/5	atrial fibrillation	MESH:D001281	therapeutic	3859260
C0004238	dofetilide	C063533	115256-11-6	atrial fibrillation	MESH:D001281	therapeutic	10651390
C0004238	erythromycin	D004917	114-07-8	atrial fibrillation	MESH:D001281	marker/mechanism	2495120
C0004238	fluorouracil	D005472	51-21-8	atrial fibrillation	MESH:D001281	marker/mechanism	15855175
C0004238	fluoxetine	D005473	54910-89-3	atrial fibrillation	MESH:D001281	marker/mechanism	2016253
C0004238	gemcitabine	C056507	103882-84-4	atrial fibrillation	MESH:D001281	marker/mechanism	10847470
C0004238	ibutilide	C067192	130350-52-6	atrial fibrillation	MESH:D001281	therapeutic	10569674
C0004238	labetalol	D007741	36894-69-6	atrial fibrillation	MESH:D001281	therapeutic	9698967
C0004238	lidocaine	D008012	137-58-6	atrial fibrillation	MESH:D001281	marker/mechanism	576484
C0004238	loxapine	D008152	1977/10/2	atrial fibrillation	MESH:D001281	marker/mechanism	7114310
C0004238	melphalan	D008558	148-82-3	atrial fibrillation	MESH:D001281	marker/mechanism	10373065
C0004238	mesna	D015080	19767-45-4	atrial fibrillation	MESH:D001281	marker/mechanism	16247745
C0004238	metoprolol	D008790	37350-58-6	atrial fibrillation	MESH:D001281	marker/mechanism	16513452
C0004238	metoprolol	D008790	37350-58-6	atrial fibrillation	MESH:D001281	therapeutic	18294935
C0004238	milrinone	D020105	78415-72-2	atrial fibrillation	MESH:D001281	marker/mechanism	18824641
C0004238	mitoxantrone	D008942	65271-80-9	atrial fibrillation	MESH:D001281	marker/mechanism	16088176
C0004238	morphine	D009020	57-27-2	atrial fibrillation	MESH:D001281	marker/mechanism	19378534
C0004238	nicotine	D009538	-	atrial fibrillation	MESH:D001281	marker/mechanism	12713677
C0004238	olanzapine	C076029	132539-06-1	atrial fibrillation	MESH:D001281	marker/mechanism	18480700
C0004238	paclitaxel	D017239	-	atrial fibrillation	MESH:D001281	marker/mechanism	10052252
C0004238	pentagastrin	D010418	5534-95-2	atrial fibrillation	MESH:D001281	marker/mechanism	7231470
C0004238	pentobarbital	D010424	76-74-4	atrial fibrillation	MESH:D001281	marker/mechanism	18980425
C0004238	phenylephrine	D010656	59-42-7	atrial fibrillation	MESH:D001281	marker/mechanism	19004376
C0004238	propranolol	D011433	525-66-6	atrial fibrillation	MESH:D001281	marker/mechanism	8908332
C0004238	propranolol	D011433	525-66-6	atrial fibrillation	MESH:D001281	therapeutic	3709557
C0004238	ranolazine	D000069458	-	atrial fibrillation	MESH:D001281	therapeutic	19698954
C0004238	sotalol	D013015	3930-20-9	atrial fibrillation	MESH:D001281	therapeutic	10496434
C0004238	spironolactone	D013148	1952/1/7	atrial fibrillation	MESH:D001281	therapeutic	20082611
C0004238	succinylcholine	D013390	306-40-1	atrial fibrillation	MESH:D001281	marker/mechanism	5492183
C0004238	thiotepa	D013852	52-24-4	atrial fibrillation	MESH:D001281	marker/mechanism	9676843
C0004238	timolol	D013999	26839-75-8	atrial fibrillation	MESH:D001281	therapeutic	41449
C0004238	valsartan	D000068756	-	atrial fibrillation	MESH:D001281	therapeutic	15864246
C0004238	vinorelbine	C030852	71486-22-1	atrial fibrillation	MESH:D001281	marker/mechanism	11165408
C0004238	zoledronic acid	C088658	-	atrial fibrillation	MESH:D001281	marker/mechanism	17476024

FDA approved drug and dosage information(Total Drugs:14)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D001281	cipro	ciprofloxacin	400MG/40ML (10MG/ML)	INJECTABLE;INJECTION	Discontinued	None	Yes	No
MESH:D001281	cipro	ciprofloxacin	250MG/5ML	FOR SUSPENSION;ORAL	Prescription	AB	Yes	No
MESH:D001281	diovan	valsartan	80MG	CAPSULE;ORAL	Discontinued	None	No	No
MESH:D001281	diovan	valsartan	80MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D001281	zometa	zoledronic acid	EQ 4MG BASE/VIAL Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	INJECTABLE;IV (INFUSION)	Discontinued	None	Yes	No
MESH:D001281	zometa	zoledronic acid	EQ 4MG BASE/VIAL	INJECTABLE; IV (INFUSION)	Prescription	None	No	No
MESH:D001281	zyprexa	olanzapine	2.5MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D001281	zyprexa	olanzapine	10MG/VIAL	INJECTABLE;INTRAMUSCULAR	Prescription	AP	Yes	Yes
MESH:D001281	zyprexa	olanzapine	2.5MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D001281	zyprexa	olanzapine	10MG/VIAL	INJECTABLE;INTRAMUSCULAR	Prescription	AP	Yes	Yes
MESH:D001281	ofirmev	acetaminophen	1GM/100ML (10MG/ML)	SOLUTION;IV (INFUSION)	Prescription	AP	Yes	Yes
MESH:D001281	ofirmev	acetaminophen	1GM/100ML (10MG/ML)	SOLUTION;IV (INFUSION)	Prescription	AP	Yes	Yes
MESH:D001281	acetaminophen	acetaminophen	650MG	SUPPOSITORY;RECTAL	Over-the-counter	None	Yes	Yes
MESH:D001281	acetaminophen	acetaminophen	650MG	SUPPOSITORY;RECTAL	Over-the-counter	None	Yes	Yes

FDA labeling changes(Total Drugs:14)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D001281	03/25/2004	cipro	ciprofloxacin	Complicated UTI and pyelonephritis	Indicated for the treatment of complicated urinary tract infections (cUTIs) and pyelonephritis in pediatric patients 1 17 years of age Not drug of first choice due to increased adverse events compared to controls including events related to joints and/or surrounding tissues Information on PK and dose in pediatric patients 1 17 years of age The most frequent adverse events observed within 6 weeks of treatment initiation during the cUTI clinical trial were gastrointestinal 15% compared to 9% and musculoskeletal 9.3% compared to 6% in ciprofloxacin-treated compared to control-treated patients, respectively	Labeling	B	-	-	-	Bayer	12/18/2003	FALSE'
MESH:D001281	03/25/2004	cipro	ciprofloxacin	Complicated UTI and pyelonephritis	Indicated for the treatment of complicated urinary tract infections (cUTIs) and pyelonephritis in pediatric patients 1 17 years of age Not drug of first choice due to increased adverse events compared to controls including events related to joints and/or surrounding tissues Information on PK and dose in pediatric patients 1 17 years of age The most frequent adverse events observed within 6 weeks of treatment initiation during the cUTI clinical trial were gastrointestinal 15% compared to 9% and musculoskeletal 9.3% compared to 6% in ciprofloxacin-treated compared to control-treated patients, respectively	Labeling	B	-	-	-	Bayer	12/18/2003	FALSE'
MESH:D001281	11/29/2007	diovan	valsartan	Hypertension	Labeling for 6-16 years of age Not recommended for pediatric patients less than 6 years due to safety findings possibly related to treatment or with glomerular filtration rate < 30mL/min/1.73m2 Information on dose, clinical studies in 1-16 years and pharmacokinetics No relevant differences were identified between adverse experience profile for pediatric patients and that previously reported for adult patients Information on preparation of a suspension	Labeling	B	-	-	-	Novartis	8/8/2007	FALSE'
MESH:D001281	11/29/2007	diovan	valsartan	Hypertension	Labeling for 6-16 years of age Not recommended for pediatric patients less than 6 years due to safety findings possibly related to treatment or with glomerular filtration rate < 30mL/min/1.73m2 Information on dose, clinical studies in 1-16 years and pharmacokinetics No relevant differences were identified between adverse experience profile for pediatric patients and that previously reported for adult patients Information on preparation of a suspension	Labeling	B	-	-	-	Novartis	8/8/2007	FALSE'
MESH:D001281	03/20/2008	zometa	zoledronic acid	Severe osteogenesis imperfecta	Zoledronic acid is not indicated for use in children Safety and effectiveness was studied in 152 pediatric patients with severe osteogenesis imperfecta aged 1 - 17 years. At one year, increases in BMD were observed in the zoledronic acid treatment group but the changes did not necessarily correlate with the risk for fracture or the incidence or severity of chronic bone pain Information on PK, clinical study, and AE profile	Labeling	B	-	-	-	Novartis	12/21/2007	FALSE'
MESH:D001281	03/20/2008	zometa	zoledronic acid	Severe osteogenesis imperfecta	Zoledronic acid is not indicated for use in children Safety and effectiveness was studied in 152 pediatric patients with severe osteogenesis imperfecta aged 1 - 17 years. At one year, increases in BMD were observed in the zoledronic acid treatment group but the changes did not necessarily correlate with the risk for fracture or the incidence or severity of chronic bone pain Information on PK, clinical study, and AE profile	Labeling	B	-	-	-	Novartis	12/21/2007	FALSE'
MESH:D001281	08/14/2008	zyprexa	olanzapine	schizophrenia; bipolar disorder	Safety and effectiveness have not been established for patients less than 18 years of age In an analysis of placebo-controlled olanzapine monotherapy studies of adolescent patients, including those with schizophrenia or bipolar disorder, olanzapine was associated with: oHyperglycemia - a statistically significantly greater mean change in fasting glucose levels compared to placebo oHyperlipidemia statistically significant increases compared to placebo in fasting triglycerides, fasting total cholesterol and fasting LDL cholesterol oWeight gain olanzapine treated patients gained an average of 4.6 kg, compared to an average of 0.3 kg in placebo-treated patients with a median exposure of 3 weeks; Average weight gain during long-term therapy was 7.4 kg	-	B	-	-	-	Lilly	10/1/2007	FALSE'
MESH:D001281	08/14/2008	zyprexa	olanzapine	schizophrenia; bipolar disorder	Safety and effectiveness have not been established for patients less than 18 years of age In an analysis of placebo-controlled olanzapine monotherapy studies of adolescent patients, including those with schizophrenia or bipolar disorder, olanzapine was associated with: oHyperglycemia - a statistically significantly greater mean change in fasting glucose levels compared to placebo oHyperlipidemia statistically significant increases compared to placebo in fasting triglycerides, fasting total cholesterol and fasting LDL cholesterol oWeight gain olanzapine treated patients gained an average of 4.6 kg, compared to an average of 0.3 kg in placebo-treated patients with a median exposure of 3 weeks; Average weight gain during long-term therapy was 7.4 kg	-	B	-	-	-	Lilly	10/1/2007	FALSE'
MESH:D001281	4/12/2009	zyprexa	olanzapine	Treatment of manic or mixed episodes of bipolar I disorder and schizophrenia in adolescents ages 13-17	Extended schizophrenia and manic or mixed episodes of bipolar I disorder indications from adults to adolescents 1317 years of age Safety and effectiveness in children < 13 years of age have not been established Recommended starting dose for adolescents is lower than that for adults Compared to patients from adult clinical trials, adolescents were likely to gain more weight, experience increased sedation, and have greater increases in total cholesterol, triglycerides, LDL cholesterol, prolactin and hepatic transaminase levels Information on dosing, adverse reactions, pharmacokinetics, clinical studies	Labeling	B	-	-	-	Lilly	10/1/2007	TRUE'
MESH:D001281	4/12/2009	zyprexa	olanzapine	Treatment of manic or mixed episodes of bipolar I disorder and schizophrenia in adolescents ages 13-17	Extended schizophrenia and manic or mixed episodes of bipolar I disorder indications from adults to adolescents 1317 years of age Safety and effectiveness in children < 13 years of age have not been established Recommended starting dose for adolescents is lower than that for adults Compared to patients from adult clinical trials, adolescents were likely to gain more weight, experience increased sedation, and have greater increases in total cholesterol, triglycerides, LDL cholesterol, prolactin and hepatic transaminase levels Information on dosing, adverse reactions, pharmacokinetics, clinical studies	Labeling	B	-	-	-	Lilly	10/1/2007	TRUE'
MESH:D001281	2/11/2010	ofirmev	acetaminophen	Management of mild-to-moderate pain, for the management of moderate-to-severe pain with adjunctive opioid analgesics, and for the reduction of fever	The safety and effectiveness of Ofirmev for the treatment of acute pain and fever in pediatric patients ages 2 years and older is supported by evidence from adequate and well-controlled studies of Ofirmev in adults. Additional safety and PK data was collected in 355 from premature neonates to adolescents. The effectiveness of Ofirmev for the treatment of acute pain and fever has not been studied in pediatric patients < 2 years of age.The PK exposure of Ofirmev observed in children and adolescents is similar to adults, but higher in neonates and infants. Dosing simulations from PK data in infants and neonates suggest that dose reductions of 33% in infants 1 month to < 2 years of age, and 50% in neonates up to 28 days, with a minimum dosing interval of 6 hours, will produce a PK exposure similar to that observed in children age 2 years and olderMost common adverse reactions in pediatric patients were nausea, vomiting, constipation, pruritus, agitation, and atelectasis.Information on dosing, clinical studies, adverse reactions and PK parametersNew dosage form and route of administration	Labeling	-	P	-	-	Cadence	-	FALSE'
MESH:D001281	01/27/2017	ofirmev	acetaminophen	Treatmeny of pain and fever in pediatric patients birth to 2 years	Treatment of pain Efficacy was not demonstrated in pediatric patients younger than 2 years in a double-blind, placebo-controlled study of 198 pediatric patients younger than 2 years. Pediatric patients less than 2 years of age, including neonates from 28 to 40 weeks gestational age at birth, were randomized to receive opioid plus acetaminophen or opioid plus placebo. No difference in analgesic effect of intravenous acetaminophen, measured by assessment of reduced need for additional opioid treatment for pain control, was observed. Treatment of fever The safety and effectiveness for the treatment of fever in pediatric patients, including premature neonates born at 32 weeks or greater gestation is supported by adequate and well-controlled studies of Ofirmev in adults, clinical studies in 244 pediatric patients 2 years and older, and safety and pharmacokinetic data from 239 patients younger than 2 years including neonates 32 weeks or greater gestational age. Information on dosing, clinical trials. Postmarketing study.	Labeling	-	-	B,P	-	Mallinckrodt	11/7/2016	FALSE
MESH:D001281	2/11/2010	ofirmev	acetaminophen	Management of mild-to-moderate pain, for the management of moderate-to-severe pain with adjunctive opioid analgesics, and for the reduction of fever	The safety and effectiveness of Ofirmev for the treatment of acute pain and fever in pediatric patients ages 2 years and older is supported by evidence from adequate and well-controlled studies of Ofirmev in adults. Additional safety and PK data was collected in 355 from premature neonates to adolescents. The effectiveness of Ofirmev for the treatment of acute pain and fever has not been studied in pediatric patients < 2 years of age.The PK exposure of Ofirmev observed in children and adolescents is similar to adults, but higher in neonates and infants. Dosing simulations from PK data in infants and neonates suggest that dose reductions of 33% in infants 1 month to < 2 years of age, and 50% in neonates up to 28 days, with a minimum dosing interval of 6 hours, will produce a PK exposure similar to that observed in children age 2 years and olderMost common adverse reactions in pediatric patients were nausea, vomiting, constipation, pruritus, agitation, and atelectasis.Information on dosing, clinical studies, adverse reactions and PK parametersNew dosage form and route of administration	Labeling	-	P	-	-	Cadence	-	FALSE'
MESH:D001281	01/27/2017	ofirmev	acetaminophen	Treatmeny of pain and fever in pediatric patients birth to 2 years	Treatment of pain Efficacy was not demonstrated in pediatric patients younger than 2 years in a double-blind, placebo-controlled study of 198 pediatric patients younger than 2 years. Pediatric patients less than 2 years of age, including neonates from 28 to 40 weeks gestational age at birth, were randomized to receive opioid plus acetaminophen or opioid plus placebo. No difference in analgesic effect of intravenous acetaminophen, measured by assessment of reduced need for additional opioid treatment for pain control, was observed. Treatment of fever The safety and effectiveness for the treatment of fever in pediatric patients, including premature neonates born at 32 weeks or greater gestation is supported by adequate and well-controlled studies of Ofirmev in adults, clinical studies in 244 pediatric patients 2 years and older, and safety and pharmacokinetic data from 239 patients younger than 2 years including neonates 32 weeks or greater gestational age. Information on dosing, clinical trials. Postmarketing study.	Labeling	-	-	B,P	-	Mallinckrodt	11/7/2016	FALSE