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PedAM

Pediatric Disease Annotations & Medicines



   asthma
  

Disease ID 385
Disease asthma
Definition
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Synonym
#NAME?
airway hyperreactivity
asthma (disorder)
asthma (disorder) [ambiguous]
asthma [disease/finding]
asthma bronchial
asthma disorders
asthma nos
asthma nos (disorder)
asthma unspecified
asthma unspecified (disorder)
asthma, bronchial
asthma, nos
asthma, unspecified
asthmas
asthmatic
asthmatics
br asthma
bronchial asthma
bronchial asthma, nos
bronchitic asthma
OMIM
DOID
UMLS
C0004096
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:264)
C0035455  |  rhinitis  |  173
C2607914  |  allergic rhinitis  |  118
C0028754  |  obesity  |  111
C0011570  |  depression  |  49
C0004096  |  asthma  |  39
C0003467  |  anxiety  |  27
C0006277  |  bronchitis  |  23
C0032285  |  pneumonia  |  20
C0042769  |  viral infection  |  20
C0013595  |  eczema  |  20
C0017168  |  oesophageal reflux  |  18
C0017168  |  esophageal reflux  |  18
C0011847  |  diabetes  |  17
C0006271  |  bronchiolitis  |  16
C0011615  |  atopic dermatitis  |  16
C0017168  |  gastroesophageal reflux  |  16
C0004030  |  aspergillosis  |  16
C0021400  |  influenza  |  14
C0024115  |  pulmonary disease  |  14
C0024115  |  lung disease  |  14
C0004031  |  allergic bronchopulmonary aspergillosis  |  13
C0037199  |  sinusitis  |  13
C0042769  |  virus infection  |  13
C0024117  |  chronic obstructive pulmonary disease  |  13
C0011603  |  dermatitis  |  12
C0035204  |  respiratory disease  |  12
C0020538  |  hypertension  |  11
C0042769  |  viral infections  |  11
C0017168  |  esophageal reflux disease  |  11
C0600260  |  obstructive pulmonary disease  |  11
C0155877  |  allergic asthma  |  11
C0016470  |  food allergy  |  11
C0028754  |  adiposity  |  10
C0042384  |  vasculitis  |  10
C1145670  |  respiratory failure  |  10
C0017168  |  gastroesophageal reflux disease  |  10
C0042870  |  vitamin d deficiency  |  10
C0042870  |  vitamin d defic  |  10
C0032285  |  pneumoniae  |  10
C0013990  |  emphysema  |  9
C0948265  |  metabolic syndrome  |  8
C0007222  |  cardiovascular disease  |  8
C0010674  |  cystic fibrosis  |  8
C0042373  |  vascular disease  |  8
C0011849  |  diabetes mellitus  |  7
C0002895  |  sickle cell disease  |  7
C0032285  |  lung inflammation  |  7
C0242379  |  lung cancer  |  6
C0006267  |  bronchiectasis  |  6
C0009763  |  conjunctivitis  |  6
C0018621  |  hay fever  |  6
C0026934  |  mycoplasma  |  6
C0018621  |  seasonal allergic rhinitis  |  5
C0016470  |  food allergies  |  5
C0035204  |  respiratory diseases  |  5
C0032285  |  pulmonary inflammation  |  5
C0004623  |  bacterial infections  |  4
C0600260  |  obstructive lung disease  |  4
C0008148  |  chlamydia  |  4
C0004096  |  bronchial asthma  |  4
C0032302  |  mycoplasma pneumonia  |  4
C0021831  |  bowel disease  |  4
C1704214  |  xanthogranuloma  |  4
C0004623  |  bacterial infection  |  4
C0018621  |  pollen allergy  |  4
C0007222  |  cardiovascular diseases  |  3
C0025007  |  measles  |  3
C0011854  |  type 1 diabetes  |  3
C0008728  |  churg-strauss syndrome  |  3
C0024115  |  lung diseases  |  3
C0029456  |  osteoporosis  |  3
C0008711  |  chronic rhinitis  |  3
C0002871  |  anemia  |  3
C0851578  |  sleep disorders  |  3
C0042373  |  vascular diseases  |  3
C0034068  |  pulmonary eosinophilia  |  3
C0037315  |  sleep-disordered breathing  |  3
C0030920  |  peptic ulcer  |  3
C0030920  |  peptic ulcer disease  |  3
C0018799  |  heart disease  |  3
C0577620  |  nut allergy  |  3
C0011334  |  caries  |  3
C0009443  |  common cold  |  3
C0520679  |  obstructive sleep apnea  |  3
C0021390  |  inflammatory bowel disease  |  3
C0036341  |  schizophrenia  |  3
C0014868  |  esophagitis  |  3
C0002020  |  alexithymia  |  3
C0037315  |  sleep apnea  |  3
C0036202  |  sarcoidosis  |  3
C1510471  |  hypovitaminosis  |  2
C0009766  |  allergic conjunctivitis  |  2
C0028432  |  nasal disease  |  2
C0006142  |  breast cancer  |  2
C0021053  |  immune disease  |  2
C0033860  |  psoriasis  |  2
C0027051  |  myocardial infarct  |  2
C0029882  |  otitis media  |  2
C0011334  |  dental caries  |  2
C0032269  |  pneumococcal infections  |  2
C0006017  |  pertussis  |  2
C0035579  |  rickets  |  2
C0024473  |  magnesium deficiency  |  2
C0024117  |  chronic obstructive pulmonary disease (copd)  |  2
C0010068  |  coronary heart disease  |  2
C0409974  |  lupus erythematosus  |  2
C0030319  |  panic disorder  |  2
C0003864  |  arthritis  |  2
C0027051  |  myocardial infarction  |  2
C0038218  |  acute severe asthma  |  2
C0009319  |  colitis  |  2
C0155877  |  atopic asthma  |  2
C0009324  |  ulcerative colitis  |  2
C0031117  |  peripheral neuropathy  |  2
C0035579  |  hypovitaminosis d  |  2
C0024530  |  malaria  |  2
C0003873  |  rheumatoid arthritis  |  2
C0742343  |  acute chest syndrome  |  2
C0042109  |  urticaria  |  2
C0041296  |  tuberculosis  |  2
C0022104  |  irritable bowel syndrome  |  2
C0376358  |  prostate cancer  |  2
C0018621  |  pollinosis  |  2
C0026769  |  multiple sclerosis  |  2
C0026946  |  mycosis  |  2
C0032269  |  pneumococcal infection  |  2
C0024141  |  systemic lupus erythematosus  |  2
C0022658  |  renal disease  |  2
C0024117  |  chronic airflow limitation  |  2
C0036205  |  pulmonary sarcoidosis  |  2
C0019158  |  hepatitis  |  2
C0017168  |  acid reflux  |  2
C0021053  |  immune dysfunction  |  2
C0032326  |  pneumothorax  |  2
C0004352  |  autism  |  2
C0037317  |  sleep disturbance  |  2
C0559469  |  egg allergy  |  2
C0442874  |  neuropathy  |  2
C0034065  |  pulmonary embolism  |  2
C0001125  |  lactic acidosis  |  2
C0149931  |  migraine  |  2
C0011615  |  atopic eczema  |  2
C0019163  |  hepatitis b  |  1
C0206180  |  anaplastic large-cell lymphoma  |  1
C0001623  |  hypoadrenalism  |  1
C0020550  |  hyperthyroidism  |  1
C0038218  |  status asthmaticus  |  1
C0020807  |  idiopathic pulmonary hemosiderosis  |  1
C0013537  |  eclampsia  |  1
C0019114  |  hemosiderosis  |  1
C0028756  |  morbid obesity  |  1
C0022658  |  kidney disease  |  1
C0221757  |  aat deficiency  |  1
C0019829  |  hodgkin's lymphoma  |  1
C0024117  |  chronic airway obstruction  |  1
C0006287  |  bronchopulmonary dysplasia  |  1
C0032371  |  poliomyelitis  |  1
C0022104  |  irritable bowel  |  1
C0006261  |  bronchial diseases  |  1
C0027059  |  myocarditis  |  1
C0878544  |  cardiomyopathy  |  1
C0028756  |  severe obesity  |  1
C0026946  |  fungal infection  |  1
C0024117  |  chronic obstructive lung disease  |  1
C0036203  |  cutaneous sarcoidosis  |  1
C1262481  |  eosinophilic gastroenteritis  |  1
C0007113  |  rectal cancer  |  1
C0041671  |  attention deficit disorder  |  1
C0038463  |  strongyloides infection  |  1
C0034063  |  pulmonary edema  |  1
C0034072  |  cor pulmonale  |  1
C0020807  |  pulmonary hemosiderosis  |  1
C0600260  |  obstructive airway disease  |  1
C0017168  |  gastro-esophageal reflux  |  1
C0747256  |  parasitic infection  |  1
C0242459  |  loeffler's syndrome  |  1
C0015645  |  fasciitis  |  1
C0012569  |  diplopia  |  1
C0694548  |  cough variant asthma  |  1
C0018802  |  congestive heart failure  |  1
C0021400  |  influenzae  |  1
C0494491  |  mononeuropathy  |  1
C0009402  |  colorectal cancer  |  1
C0021831  |  intestinal disease  |  1
C0017160  |  gastroenteritis  |  1
C0006264  |  bronchial tumor  |  1
C0017658  |  glomerulonephritis  |  1
C0020538  |  systemic arterial hypertension  |  1
C1398341  |  sinus infection  |  1
C0020538  |  systemic hypertension  |  1
C0007785  |  cerebral ischemia  |  1
C0041466  |  typhoid fever  |  1
C0011860  |  type 2 diabetes  |  1
C0004245  |  av block  |  1
C0000786  |  spontaneous abortions  |  1
C0013295  |  duodenal ulcer  |  1
C0004096  |  airway hyperreactivity  |  1
C0079840  |  milk allergy  |  1
C0004153  |  atherosclerosis  |  1
C0086543  |  cataract  |  1
C0030920  |  peptic ulcers  |  1
C0040128  |  thyroid disorders  |  1
C0019196  |  hepatitis c  |  1
C0022735  |  klinefelter's syndrome  |  1
C0007194  |  hypertrophic obstructive cardiomyopathy  |  1
C0007194  |  obstructive cardiomyopathy  |  1
C0021171  |  incontinentia pigmenti  |  1
C0085278  |  antiphospholipid antibody syndrome  |  1
C0152025  |  polyneuropathy  |  1
C0497327  |  dementia  |  1
C0018553  |  cowden syndrome  |  1
C0039730  |  thalassemia  |  1
C0403416  |  crescentic glomerulonephritis  |  1
C0206141  |  hypereosinophilic syndrome  |  1
C0003950  |  ascariasis  |  1
C0149925  |  small cell carcinoma  |  1
C0004245  |  atrioventricular block  |  1
C0037274  |  skin diseases  |  1
C0004936  |  mental disorders  |  1
C0334421  |  glomangioma  |  1
C0026946  |  fungal infections  |  1
C0020456  |  hyperglycaemia  |  1
C0016470  |  food hypersensitivity  |  1
C0037317  |  sleep disturbances  |  1
C0017178  |  gastrointestinal disease  |  1
C0024299  |  lymphoma  |  1
C0009447  |  common variable immunodeficiency  |  1
C0021775  |  intermittent claudication  |  1
C0014175  |  endometriosis  |  1
C0037274  |  skin disease  |  1
C0036203  |  cutaneous sarcoid  |  1
C0038436  |  post-traumatic stress disorder  |  1
C0024117  |  chronic airways disease  |  1
C0020459  |  hyperinsulinemia  |  1
C0038013  |  ankylosing spondylitis  |  1
C0017601  |  glaucoma  |  1
C0026896  |  myasthenia gravis  |  1
C0041466  |  typhoid  |  1
C0038218  |  severe asthma attack  |  1
C0003469  |  anxiety disorder  |  1
C0024117  |  chronic airway disease  |  1
C0032914  |  preeclampsia  |  1
C0006325  |  bruxism  |  1
C0020538  |  high blood pressure  |  1
C0020542  |  pulmonary hypertension  |  1
C0002895  |  sickle cell anemia  |  1
C0018801  |  heart failure  |  1
C0751967  |  relapsing-remitting multiple sclerosis  |  1
C0040127  |  thyroid crisis  |  1
C0023976  |  long qt syndrome  |  1
C0026986  |  myelodysplastic syndrome  |  1
C0031036  |  periarteritis nodosa  |  1
C0085207  |  maternal diabetes  |  1
C0032302  |  mycoplasma pneumoniae pneumonia  |  1
C0162871  |  abdominal aortic aneurysm  |  1
C0003469  |  anxiety disorders  |  1
C0007131  |  nsclc  |  1
C0175691  |  dubowitz syndrome  |  1
C0000786  |  spontaneous abortion  |  1
C0006285  |  bronchopneumonia  |  1
C0235974  |  pancreatic cancer  |  1
C0017168  |  gastro-oesophageal reflux  |  1
C0022353  |  neonatal jaundice  |  1
C0221074  |  postnatal depression  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:115)
HLA-DRB1  |  3123  |  CTD_human
CHI3L1  |  1116  |  UniProtKB-KW
CLEC16A  |  23274  |  GWASCAT
TNF  |  7124  |  CTD_human
NQO1  |  1728  |  CTD_human
HLA-DQA1  |  3117  |  CTD_human;GWASCAT
SOD1  |  6647  |  CTD_human
ICAM1  |  3383  |  CTD_human
TGFB1  |  7040  |  CTD_human
SLC22A5  |  6584  |  GWASCAT
BCL2  |  596  |  CTD_human
PLA2G7  |  7941  |  CTD_human;UniProtKB-KW
PLAU  |  5328  |  CTD_human
SMAD3  |  4088  |  GWASCAT
IL13  |  3596  |  CTD_human;GWASCAT
TIMP3  |  7078  |  CTD_human
IL6R  |  3570  |  GWASCAT
HMOX1  |  3162  |  CTD_human
CCL2  |  6347  |  CTD_human
EDN1  |  1906  |  CTD_human
HLA-DPA1  |  3113  |  GWASCAT
C6orf10  |  10665  |  GWASCAT
MMP9  |  4318  |  CTD_human
PARP1  |  142  |  CTD_human
TLR1  |  7096  |  GWASCAT
IL1B  |  3553  |  CTD_human
NOS2  |  4843  |  CTD_human
NPY  |  4852  |  CTD_human
HLA-DPB1  |  3115  |  CTD_human;GWASCAT
ARG1  |  383  |  CTD_human
SCGB3A2  |  117156  |  CTD_human
ERBB4  |  2066  |  GWASCAT
VEGFA  |  7422  |  CTD_human
IL12B  |  3593  |  CTD_human
PTEN  |  5728  |  CTD_human
IKZF3  |  22806  |  GWASCAT
CAT  |  847  |  CTD_human
TBX21  |  30009  |  CTD_human;UniProtKB-KW
HLA-DQB1  |  3119  |  CTD_human
HNMT  |  3176  |  CTD_human
ADRB2  |  154  |  CTD_human
VAV3  |  10451  |  GWASCAT
IL1RN  |  3557  |  CTD_human
PYHIN1  |  149628  |  CTD_human;GWASCAT
SCGB1A1  |  7356  |  CTD_human
PRKG1  |  5592  |  GWASCAT
RORA  |  6095  |  GWASCAT
GSTP1  |  2950  |  CTD_human
SPRR2B  |  6701  |  CTD_human
ALOX5  |  240  |  CTD_human
MYB  |  4602  |  CTD_human
PSAP  |  5660  |  GWASCAT
PPP2CA  |  5515  |  CTD_human
IL2RB  |  3560  |  GWASCAT
HSD11B2  |  3291  |  CTD_human
ALDH2  |  217  |  CTD_human
DNAH5  |  1767  |  CTD_human
GSTM1  |  2944  |  CTD_human
IRAK3  |  11213  |  UniProtKB-KW
CCL5  |  6352  |  CTD_human
MMP10  |  4319  |  CTD_human
IL4  |  3565  |  CTD_human
IL5  |  3567  |  CTD_human
PDE4D  |  5144  |  CTD_human;GWASCAT
PDE4B  |  5142  |  CTD_human
FBXL7  |  23194  |  GWASCAT
ABI3BP  |  25890  |  GWASCAT
ARG2  |  384  |  CTD_human
CDHR3  |  222256  |  CTD_human;GWASCAT;UniProtKB-KW
XKR6  |  286046  |  GWASCAT
DENND1B  |  163486  |  UniProtKB-KW
CD14  |  929  |  CTD_human
CCL11  |  6356  |  CTD_human
TSLP  |  85480  |  CTD_human
PTGDR  |  5729  |  UniProtKB-KW
GSDMA  |  284110  |  GWASCAT
RAP1GAP2  |  23108  |  GWASCAT
PMEL  |  6490  |  GWASCAT
CRB1  |  23418  |  GWASCAT
ORMDL3  |  94103  |  CTD_human;UniProtKB-KW
ADCYAP1R1  |  117  |  CTD_human
IKZF4  |  64375  |  GWASCAT
KIF3A  |  11127  |  CTD_human
AREG  |  374  |  CTD_human
TNC  |  3371  |  CTD_human
MUC7  |  4589  |  CTD_human;UniProtKB-KW
CTNNA3  |  29119  |  CTD_human
ADAM33  |  80332  |  UniProtKB-KW
IFNL3  |  282617  |  CTD_human
NOTCH4  |  4855  |  GWASCAT
PBX2  |  5089  |  GWASCAT
ADCY2  |  108  |  CTD_human
RAD50  |  10111  |  CTD_human;GWASCAT
GSDMB  |  55876  |  CTD_human;GWASCAT
DPP10  |  57628  |  UniProtKB-KW
HLA-G  |  3135  |  CTD_human
IL1RL1  |  9173  |  CTD_human;GWASCAT
TNS1  |  7145  |  GWASCAT
HPSE2  |  60495  |  GWASCAT
KLHL5  |  51088  |  GWASCAT
WDR36  |  134430  |  CTD_human
PHF11  |  51131  |  CTD_human
NPSR1  |  387129  |  CTD_human;UniProtKB-KW
IL33  |  90865  |  CTD_human;GWASCAT
DNMT1  |  1786  |  CTD_human
RNASE3  |  6037  |  CTD_human
SLC30A8  |  169026  |  GWASCAT
CXCL14  |  9547  |  CTD_human
IL18R1  |  8809  |  GWASCAT
GAB1  |  2549  |  GWASCAT
TRPA1  |  8989  |  CTD_human
CDK2  |  1017  |  GWASCAT
BGLAP  |  632  |  CTD_human
KRT19  |  3880  |  CTD_human
HCG23  |  414764  |  GWASCAT
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:484)
4363  |  ABCC1  |  infer
28  |  ABO  |  infer
1636  |  ACE  |  infer
52  |  ACP1  |  infer
100  |  ADA  |  infer
80332  |  ADAM33  |  infer
103  |  ADAR  |  infer
108  |  ADCY2  |  infer
115  |  ADCY9  |  infer
128  |  ADH5  |  infer
134  |  ADORA1  |  infer
147  |  ADRA1B  |  infer
154  |  ADRB2  |  infer
178  |  AGL  |  infer
23287  |  AGTPBP1  |  infer
57379  |  AICDA  |  infer
9472  |  AKAP6  |  infer
217  |  ALDH2  |  infer
240  |  ALOX5  |  infer
241  |  ALOX5AP  |  infer
286  |  ANK1  |  infer
313  |  AOAH  |  infer
10565  |  ARFGEF1  |  infer
383  |  ARG1  |  infer
384  |  ARG2  |  infer
6315  |  ATXN8OS  |  infer
2683  |  B4GALT1  |  infer
343472  |  BARHL2  |  infer
624  |  BDKRB2  |  infer
627  |  BDNF  |  infer
7439  |  BEST1  |  infer
6046  |  BRD2  |  infer
64115  |  C10orf54  |  infer
339448  |  C1orf174  |  infer
114899  |  C1QTNF3  |  infer
718  |  C3  |  infer
719  |  C3AR1  |  infer
152118  |  C3orf79  |  infer
727  |  C5  |  infer
10665  |  C6orf10  |  infer
138255  |  C9orf135  |  infer
59285  |  CACNG6  |  infer
847  |  CAT  |  infer
151278  |  CCDC140  |  infer
6346  |  CCL1  |  infer
6356  |  CCL11  |  infer
6347  |  CCL2  |  infer
6369  |  CCL24  |  infer
10344  |  CCL26  |  infer
6352  |  CCL5  |  infer
6354  |  CCL7  |  infer
1232  |  CCR3  |  infer
1234  |  CCR5  |  infer
929  |  CD14  |  infer
940  |  CD28  |  infer
64072  |  CDH23  |  infer
1017  |  CDK2  |  infer
1080  |  CFTR  |  infer
57530  |  CGN  |  infer
1116  |  CHI3L1  |  infer
27159  |  CHIA  |  infer
1118  |  CHIT1  |  infer
1124  |  CHN2  |  infer
1128  |  CHRM1  |  infer
1129  |  CHRM2  |  infer
1131  |  CHRM3  |  infer
10370  |  CITED2  |  infer
1179  |  CLCA1  |  infer
1215  |  CMA1  |  infer
149111  |  CNIH3  |  infer
246175  |  CNOT6L  |  infer
54875  |  CNTLN  |  infer
131034  |  CPNE4  |  infer
130749  |  CPO  |  infer
23418  |  CRB1  |  infer
54544  |  CRCT1  |  infer
1385  |  CREB1  |  infer
9586  |  CREB5  |  infer
1394  |  CRHR1  |  infer
1395  |  CRHR2  |  infer
167  |  CRISP1  |  infer
64109  |  CRLF2  |  infer
1436  |  CSF1R  |  infer
1437  |  CSF2  |  infer
64478  |  CSMD1  |  infer
1493  |  CTLA4  |  infer
29119  |  CTNNA3  |  infer
1501  |  CTNND2  |  infer
57703  |  CWC22  |  infer
1524  |  CX3CR1  |  infer
2833  |  CXCR3  |  infer
7852  |  CXCR4  |  infer
360170  |  CYCSP14  |  infer
26999  |  CYFIP2  |  infer
1543  |  CYP1A1  |  infer
1544  |  CYP1A2  |  infer
1591  |  CYP24A1  |  infer
1559  |  CYP2C9  |  infer
1571  |  CYP2E1  |  infer
1573  |  CYP2J2  |  infer
120227  |  CYP2R1  |  infer
1576  |  CYP3A4  |  infer
4051  |  CYP4F3  |  infer
10800  |  CYSLTR1  |  infer
57105  |  CYSLTR2  |  infer
116159  |  CYYR1  |  infer
7818  |  DAP3  |  infer
728597  |  DCDC2C  |  infer
1672  |  DEFB1  |  infer
163486  |  DENND1B  |  infer
100126446  |  DEPDC1P2  |  infer
22943  |  DKK1  |  infer
23312  |  DMXL2  |  infer
3337  |  DNAJB1  |  infer
1794  |  DOCK2  |  infer
57628  |  DPP10  |  infer
100129460  |  DPY19L1P1  |  infer
1843  |  DUSP1  |  infer
11221  |  DUSP10  |  infer
1906  |  EDN1  |  infer
1909  |  EDNRA  |  infer
1910  |  EDNRB  |  infer
1956  |  EGFR  |  infer
1958  |  EGR1  |  infer
26298  |  EHF  |  infer
60528  |  ELAC2  |  infer
1993  |  ELAVL2  |  infer
1999  |  ELF3  |  infer
2001  |  ELF5  |  infer
55140  |  ELP3  |  infer
2052  |  EPHX1  |  infer
2053  |  EPHX2  |  infer
2099  |  ESR1  |  infer
2139  |  EYA2  |  infer
100131897  |  FAM196B  |  infer
356  |  FASLG  |  infer
10516  |  FBLN5  |  infer
254170  |  FBXO33  |  infer
2204  |  FCAR  |  infer
2205  |  FCER1A  |  infer
2207  |  FCER1G  |  infer
2208  |  FCER2  |  infer
2210  |  FCGR1B  |  infer
2214  |  FCGR3A  |  infer
53834  |  FGFRL1  |  infer
2288  |  FKBP4  |  infer
2289  |  FKBP5  |  infer
2312  |  FLG  |  infer
50943  |  FOXP3  |  infer
84075  |  FSCB  |  infer
161835  |  FSIP1  |  infer
23105  |  FSTL4  |  infer
2524  |  FUT2  |  infer
2525  |  FUT3  |  infer
2534  |  FYN  |  infer
55632  |  G2E3  |  infer
2549  |  GAB1  |  infer
9568  |  GABBR2  |  infer
2625  |  GATA3  |  infer
2638  |  GC  |  infer
2730  |  GCLM  |  infer
51738  |  GHRL  |  infer
2694  |  GIF  |  infer
169792  |  GLIS3  |  infer
2778  |  GNAS  |  infer
2782  |  GNB1  |  infer
2792  |  GNGT1  |  infer
2835  |  GPR12  |  infer
2876  |  GPX1  |  infer
2879  |  GPX4  |  infer
2904  |  GRIN2B  |  infer
2911  |  GRM1  |  infer
284110  |  GSDMA  |  infer
55876  |  GSDMB  |  infer
2938  |  GSTA1  |  infer
2941  |  GSTA4  |  infer
2944  |  GSTM1  |  infer
2947  |  GSTM3  |  infer
9446  |  GSTO1  |  infer
119391  |  GSTO2  |  infer
2950  |  GSTP1  |  infer
2952  |  GSTT1  |  infer
26762  |  HAVCR1  |  infer
84868  |  HAVCR2  |  infer
8924  |  HERC2  |  infer
51191  |  HERC5  |  infer
3105  |  HLA-A  |  infer
3106  |  HLA-B  |  infer
3107  |  HLA-C  |  infer
3113  |  HLA-DPA1  |  infer
3115  |  HLA-DPB1  |  infer
3117  |  HLA-DQA1  |  infer
3118  |  HLA-DQA2  |  infer
3119  |  HLA-DQB1  |  infer
3122  |  HLA-DRA  |  infer
3123  |  HLA-DRB1  |  infer
3135  |  HLA-G  |  infer
3142  |  HLX  |  infer
3162  |  HMOX1  |  infer
3176  |  HNMT  |  infer
100131609  |  HNRNPA1P2  |  infer
3240  |  HP  |  infer
3274  |  HRH2  |  infer
9951  |  HS3ST4  |  infer
3320  |  HSP90AA1  |  infer
3326  |  HSP90AB1  |  infer
3304  |  HSPA1B  |  infer
3312  |  HSPA8  |  infer
3383  |  ICAM1  |  infer
3458  |  IFNG  |  infer
3459  |  IFNGR1  |  infer
3460  |  IFNGR2  |  infer
3500  |  IGHG1  |  infer
3502  |  IGHG3  |  infer
8518  |  IKBKAP  |  infer
3586  |  IL10  |  infer
3592  |  IL12A  |  infer
3593  |  IL12B  |  infer
3595  |  IL12RB2  |  infer
3596  |  IL13  |  infer
3597  |  IL13RA1  |  infer
3600  |  IL15  |  infer
3603  |  IL16  |  infer
3605  |  IL17A  |  infer
112744  |  IL17F  |  infer
3606  |  IL18  |  infer
8809  |  IL18R1  |  infer
3552  |  IL1A  |  infer
3553  |  IL1B  |  infer
9173  |  IL1RL1  |  infer
8808  |  IL1RL2  |  infer
3557  |  IL1RN  |  infer
3558  |  IL2  |  infer
246778  |  IL27  |  infer
3559  |  IL2RA  |  infer
3560  |  IL2RB  |  infer
90865  |  IL33  |  infer
3565  |  IL4  |  infer
3566  |  IL4R  |  infer
3567  |  IL5  |  infer
3568  |  IL5RA  |  infer
3569  |  IL6  |  infer
3570  |  IL6R  |  infer
3578  |  IL9  |  infer
3581  |  IL9R  |  infer
3631  |  INPP4A  |  infer
11213  |  IRAK3  |  infer
3659  |  IRF1  |  infer
100288517  |  ISCA1P2  |  infer
3695  |  ITGB7  |  infer
3727  |  JUND  |  infer
23189  |  KANK1  |  infer
3741  |  KCNA5  |  infer
3791  |  KDR  |  infer
643115  |  KRT223P  |  infer
220959  |  KRT8P16  |  infer
284217  |  LAMA1  |  infer
81606  |  LBH  |  infer
3952  |  LEP  |  infer
3953  |  LEPR  |  infer
57689  |  LRRC4C  |  infer
347730  |  LRRTM1  |  infer
4049  |  LTA  |  infer
4048  |  LTA4H  |  infer
4050  |  LTB  |  infer
4056  |  LTC4S  |  infer
9450  |  LY86  |  infer
4124  |  MAN2A1  |  infer
5602  |  MAPK10  |  infer
57506  |  MAVS  |  infer
4153  |  MBL2  |  infer
9645  |  MICAL2  |  infer
4321  |  MMP12  |  infer
4318  |  MMP9  |  infer
4353  |  MPO  |  infer
143098  |  MPP7  |  infer
4360  |  MRC1  |  infer
931  |  MS4A1  |  infer
2206  |  MS4A2  |  infer
932  |  MS4A3  |  infer
4513  |  MT-CO2  |  infer
4524  |  MTHFR  |  infer
23281  |  MTUS2  |  infer
4582  |  MUC1  |  infer
4583  |  MUC2  |  infer
4585  |  MUC4  |  infer
4586  |  MUC5AC  |  infer
727897  |  MUC5B  |  infer
4589  |  MUC7  |  infer
4638  |  MYLK  |  infer
282694  |  NASPP1  |  infer
9  |  NAT1  |  infer
10  |  NAT2  |  infer
89797  |  NAV2  |  infer
89795  |  NAV3  |  infer
23327  |  NEDD4L  |  infer
4745  |  NELL1  |  infer
4795  |  NFKBIL1  |  infer
4837  |  NNMT  |  infer
10392  |  NOD1  |  infer
4842  |  NOS1  |  infer
4843  |  NOS2  |  infer
4846  |  NOS3  |  infer
4855  |  NOTCH4  |  infer
64067  |  NPAS3  |  infer
4878  |  NPPA  |  infer
594857  |  NPS  |  infer
387129  |  NPSR1  |  infer
1728  |  NQO1  |  infer
9572  |  NR1D1  |  infer
2908  |  NR3C1  |  infer
10718  |  NRG3  |  infer
83714  |  NRIP2  |  infer
30010  |  NXPH1  |  infer
390433  |  OR4K13  |  infer
94103  |  ORMDL3  |  infer
5021  |  OXTR  |  infer
29780  |  PARVB  |  infer
5077  |  PAX3  |  infer
5089  |  PBX2  |  infer
65217  |  PCDH15  |  infer
5144  |  PDE4D  |  infer
5152  |  PDE9A  |  infer
5154  |  PDGFA  |  infer
5156  |  PDGFRA  |  infer
51131  |  PHF11  |  infer
54984  |  PINX1  |  infer
8395  |  PIP5K1B  |  infer
5317  |  PKP1  |  infer
5321  |  PLA2G4A  |  infer
91584  |  PLXNA4  |  infer
56937  |  PMEPA1  |  infer
11201  |  POLI  |  infer
5468  |  PPARG  |  infer
8499  |  PPFIA2  |  infer
5578  |  PRKCA  |  infer
5581  |  PRKCE  |  infer
5592  |  PRKG1  |  infer
5621  |  PRNP  |  infer
5729  |  PTGDR  |  infer
5731  |  PTGER1  |  infer
5732  |  PTGER2  |  infer
5733  |  PTGER3  |  infer
5734  |  PTGER4  |  infer
10728  |  PTGES3  |  infer
5742  |  PTGS1  |  infer
5743  |  PTGS2  |  infer
5789  |  PTPRD  |  infer
149628  |  PYHIN1  |  infer
10111  |  RAD50  |  infer
26953  |  RANBP6  |  infer
399  |  RHOH  |  infer
6037  |  RNASE3  |  infer
100147765  |  RNU7-17P  |  infer
100151647  |  RNU7-51P  |  infer
6094  |  ROM1  |  infer
6095  |  RORA  |  infer
9501  |  RPH3AL  |  infer
137107  |  RPL10AP3  |  infer
646898  |  RPL12P40  |  infer
728658  |  RPL13AP5  |  infer
442232  |  RPL17P25  |  infer
391719  |  RPL19P8  |  infer
100271449  |  RPL21P126  |  infer
645157  |  RPL21P61  |  infer
100270966  |  RPL26P25  |  infer
100133193  |  RPL32P28  |  infer
100130718  |  RPL34P26  |  infer
128748  |  RPL7AP13  |  infer
100271211  |  RPL7AP47  |  infer
729123  |  RPL7P21  |  infer
439954  |  RPL7P37  |  infer
376693  |  RPS10P7  |  infer
100271613  |  RPS15AP27  |  infer
100271607  |  RPS15AP30  |  infer
390576  |  RPS15P8  |  infer
100271235  |  RPS20P25  |  infer
100271113  |  RPS26P24  |  infer
100271585  |  RPS27P27  |  infer
652980  |  RPS28P1  |  infer
645000  |  RPS3P6  |  infer
861  |  RUNX1  |  infer
1901  |  S1PR1  |  infer
29106  |  SCG3  |  infer
7356  |  SCGB1A1  |  infer
117156  |  SCGB3A2  |  infer
6337  |  SCNN1A  |  infer
6401  |  SELE  |  infer
5265  |  SERPINA1  |  infer
12  |  SERPINA3  |  infer
5054  |  SERPINE1  |  infer
6423  |  SFRP2  |  infer
6425  |  SFRP5  |  infer
6441  |  SFTPD  |  infer
59307  |  SIGIRR  |  infer
27181  |  SIGLEC8  |  infer
57568  |  SIPA1L2  |  infer
220134  |  SKA1  |  infer
6556  |  SLC11A1  |  infer
6584  |  SLC22A5  |  infer
25769  |  SLC24A2  |  infer
57419  |  SLC24A3  |  infer
89874  |  SLC25A21  |  infer
91137  |  SLC25A46  |  infer
169026  |  SLC30A8  |  infer
85414  |  SLC45A3  |  infer
159963  |  SLC5A12  |  infer
6539  |  SLC6A12  |  infer
6534  |  SLC6A7  |  infer
4088  |  SMAD3  |  infer
64744  |  SMAP2  |  infer
64094  |  SMOC2  |  infer
8651  |  SOCS1  |  infer
6648  |  SOD2  |  infer
6662  |  SOX9  |  infer
11005  |  SPINK5  |  infer
6694  |  SPP2  |  infer
6644  |  SRIP1  |  infer
6761  |  ST2  |  infer
6771  |  STARP1  |  infer
6774  |  STAT3  |  infer
6775  |  STAT4  |  infer
6778  |  STAT6  |  infer
10963  |  STIP1  |  infer
6821  |  SUOX  |  infer
79987  |  SVEP1  |  infer
132204  |  SYNPR  |  infer
6863  |  TAC1  |  infer
6866  |  TAC3  |  infer
255061  |  TAC4  |  infer
6865  |  TACR2  |  infer
6879  |  TAF7  |  infer
6890  |  TAP1  |  infer
50834  |  TAS2R1  |  infer
30009  |  TBX21  |  infer
6915  |  TBXA2R  |  infer
7018  |  TF  |  infer
7040  |  TGFB1  |  infer
7042  |  TGFB2  |  infer
7046  |  TGFBR1  |  infer
7048  |  TGFBR2  |  infer
7049  |  TGFBR3  |  infer
7060  |  THBS4  |  infer
91937  |  TIMD4  |  infer
8914  |  TIMELESS  |  infer
7076  |  TIMP1  |  infer
81793  |  TLR10  |  infer
7097  |  TLR2  |  infer
7098  |  TLR3  |  infer
7099  |  TLR4  |  infer
10333  |  TLR6  |  infer
54106  |  TLR9  |  infer
255104  |  TMCO4  |  infer
121256  |  TMEM132D  |  infer
153396  |  TMEM161B  |  infer
80021  |  TMEM62  |  infer
3371  |  TNC  |  infer
7124  |  TNF  |  infer
8797  |  TNFRSF10A  |  infer
8795  |  TNFRSF10B  |  infer
10318  |  TNIP1  |  infer
8658  |  TNKS  |  infer
7135  |  TNNI1  |  infer
8989  |  TRPA1  |  infer
7442  |  TRPV1  |  infer
59341  |  TRPV4  |  infer
85480  |  TSLP  |  infer
55761  |  TTC17  |  infer
7278  |  TUBA3C  |  infer
10426  |  TUBGCP3  |  infer
7991  |  TUSC3  |  infer
9690  |  UBE3C  |  infer
10911  |  UTS2  |  infer
7421  |  VDR  |  infer
7422  |  VEGFA  |  infer
55717  |  WDR11  |  infer
11197  |  WIF1  |  infer
8840  |  WISP1  |  infer
400209  |  YTHDF2P1  |  infer
150244  |  ZDHHC8P1  |  infer
23613  |  ZMYND8  |  infer
163087  |  ZNF383  |  infer
23090  |  ZNF423  |  infer
92285  |  ZNF585B  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:1141)
618  |  BCYRN1  |  DISEASES
2288  |  FKBP4  |  DISEASES
1080  |  CFTR  |  DISEASES
6362  |  CCL18  |  DISEASES
126393  |  HSPB6  |  DISEASES
10344  |  CCL26  |  DISEASES
6376  |  CX3CL1  |  DISEASES
51087  |  YBX2  |  DISEASES
928  |  CD9  |  DISEASES
4257  |  MGST1  |  DISEASES
920  |  CD4  |  DISEASES
1634  |  DCN  |  DISEASES
3631  |  INPP4A  |  DISEASES
51009  |  DERL2  |  DISEASES
3385  |  ICAM3  |  DISEASES
23152  |  CIC  |  DISEASES
7132  |  TNFRSF1A  |  DISEASES
27231  |  NMRK2  |  DISEASES
3566  |  IL4R  |  DISEASES
9817  |  KEAP1  |  DISEASES
7145  |  TNS1  |  DISEASES
4804  |  NGFR  |  DISEASES
30009  |  TBX21  |  DISEASES
6583  |  SLC22A4  |  DISEASES
3902  |  LAG3  |  DISEASES
23430  |  TPSD1  |  DISEASES
5603  |  MAPK13  |  DISEASES
23411  |  SIRT1  |  DISEASES
4616  |  GADD45B  |  DISEASES
4282  |  MIF  |  DISEASES
5008  |  OSM  |  DISEASES
266629  |  SEC14L3  |  DISEASES
5594  |  MAPK1  |  DISEASES
3162  |  HMOX1  |  DISEASES
158  |  ADSL  |  DISEASES
3560  |  IL2RB  |  DISEASES
1511  |  CTSG  |  DISEASES
3002  |  GZMB  |  DISEASES
4792  |  NFKBIA  |  DISEASES
1591  |  CYP24A1  |  DISEASES
3929  |  LBP  |  DISEASES
1472  |  CST4  |  DISEASES
51311  |  TLR8  |  DISEASES
2158  |  F9  |  DISEASES
7076  |  TIMP1  |  DISEASES
2717  |  GLA  |  DISEASES
479  |  ATP12A  |  DISEASES
4313  |  MMP2  |  DISEASES
6367  |  CCL22  |  DISEASES
6361  |  CCL17  |  DISEASES
58189  |  WFDC1  |  DISEASES
10273  |  STUB1  |  DISEASES
4210  |  MEFV  |  DISEASES
3163  |  HMOX2  |  DISEASES
10423  |  CDIPT  |  DISEASES
123263  |  MTFMT  |  DISEASES
1666  |  DECR1  |  DISEASES
2936  |  GSR  |  DISEASES
8797  |  TNFRSF10A  |  DISEASES
9668  |  ZNF432  |  DISEASES
56729  |  RETN  |  DISEASES
1178  |  CLC  |  DISEASES
7040  |  TGFB1  |  DISEASES
973  |  CD79A  |  DISEASES
6822  |  SULT2A1  |  DISEASES
9545  |  RAB3D  |  DISEASES
7392  |  USF2  |  DISEASES
5444  |  PON1  |  DISEASES
51200  |  CPA4  |  DISEASES
10392  |  NOD1  |  DISEASES
6369  |  CCL24  |  DISEASES
1577  |  CYP3A5  |  DISEASES
5054  |  SERPINE1  |  DISEASES
113263  |  GLCCI1  |  DISEASES
146542  |  ZNF688  |  DISEASES
944  |  TNFSF8  |  DISEASES
6348  |  CCL3  |  DISEASES
4353  |  MPO  |  DISEASES
8288  |  EPX  |  DISEASES
1440  |  CSF3  |  DISEASES
6198  |  RPS6KB1  |  DISEASES
6347  |  CCL2  |  DISEASES
6346  |  CCL1  |  DISEASES
6357  |  CCL13  |  DISEASES
7448  |  VTN  |  DISEASES
952  |  CD38  |  DISEASES
6372  |  CXCL6  |  DISEASES
4790  |  NFKB1  |  DISEASES
3558  |  IL2  |  DISEASES
116449  |  CLNK  |  DISEASES
6688  |  SPI1  |  DISEASES
1075  |  CTSC  |  DISEASES
56253  |  CRTAM  |  DISEASES
595  |  CCND1  |  DISEASES
3587  |  IL10RA  |  DISEASES
4254  |  KITLG  |  DISEASES
969  |  CD69  |  DISEASES
6404  |  SELPLG  |  DISEASES
51561  |  IL23A  |  DISEASES
1594  |  CYP27B1  |  DISEASES
4048  |  LTA4H  |  DISEASES
4055  |  LTBR  |  DISEASES
3458  |  IFNG  |  DISEASES
2597  |  GAPDH  |  DISEASES
50813  |  COPS7A  |  DISEASES
55907  |  CMAS  |  DISEASES
57379  |  AICDA  |  DISEASES
3820  |  KLRB1  |  DISEASES
1432  |  MAPK14  |  DISEASES
9896  |  FIG4  |  DISEASES
54346  |  UNC93A  |  DISEASES
9450  |  LY86  |  DISEASES
1839  |  HBEGF  |  DISEASES
4015  |  LOX  |  DISEASES
3565  |  IL4  |  DISEASES
3567  |  IL5  |  DISEASES
2908  |  NR3C1  |  DISEASES
4057  |  LTF  |  DISEASES
11068  |  CYB561D2  |  DISEASES
374291  |  NDUFS7  |  DISEASES
3485  |  IGFBP2  |  DISEASES
3554  |  IL1R1  |  DISEASES
9173  |  IL1RL1  |  DISEASES
8809  |  IL18R1  |  DISEASES
5624  |  PROC  |  DISEASES
5657  |  PRTN3  |  DISEASES
1179  |  CLCA1  |  DISEASES
5997  |  RGS2  |  DISEASES
6402  |  SELL  |  DISEASES
4317  |  MMP8  |  DISEASES
335  |  APOA1  |  DISEASES
80306  |  MED28  |  DISEASES
5273  |  SERPINB10  |  DISEASES
1843  |  DUSP1  |  DISEASES
83887  |  TTLL2  |  DISEASES
4360  |  MRC1  |  DISEASES
1958  |  EGR1  |  DISEASES
50839  |  TAS2R10  |  DISEASES
847  |  CAT  |  DISEASES
51426  |  POLK  |  DISEASES
4852  |  NPY  |  DISEASES
7291  |  TWIST1  |  DISEASES
27019  |  DNAI1  |  DISEASES
29095  |  ORMDL2  |  DISEASES
3598  |  IL13RA2  |  DISEASES
7130  |  TNFAIP6  |  DISEASES
5266  |  PI3  |  DISEASES
5335  |  PLCG1  |  DISEASES
3581  |  IL9R  |  DISEASES
54210  |  TREM1  |  DISEASES
56848  |  SPHK2  |  DISEASES
6584  |  SLC22A5  |  DISEASES
3659  |  IRF1  |  DISEASES
718  |  C3  |  DISEASES
22918  |  CD93  |  DISEASES
2867  |  FFAR2  |  DISEASES
1236  |  CCR7  |  DISEASES
6945  |  MLX  |  DISEASES
1773  |  DNASE1  |  DISEASES
5199  |  CFP  |  DISEASES
391013  |  PLA2G2C  |  DISEASES
57622  |  LRFN1  |  DISEASES
7538  |  ZFP36  |  DISEASES
2678  |  GGT1  |  DISEASES
2952  |  GSTT1  |  DISEASES
5880  |  RAC2  |  DISEASES
3976  |  LIF  |  DISEASES
54567  |  DLL4  |  DISEASES
968  |  CD68  |  DISEASES
6351  |  CCL4  |  DISEASES
8840  |  WISP1  |  DISEASES
1215  |  CMA1  |  DISEASES
3630  |  INS  |  DISEASES
239  |  ALOX12  |  DISEASES
2006  |  ELN  |  DISEASES
59285  |  CACNG6  |  DISEASES
84313  |  VPS25  |  DISEASES
80762  |  NDFIP1  |  DISEASES
3958  |  LGALS3  |  DISEASES
23647  |  ARFIP2  |  DISEASES
23108  |  RAP1GAP2  |  DISEASES
182  |  JAG1  |  DISEASES
1401  |  CRP  |  DISEASES
1131  |  CHRM3  |  DISEASES
1116  |  CHI3L1  |  DISEASES
55303  |  GIMAP4  |  DISEASES
4922  |  NTS  |  DISEASES
10001  |  MED6  |  DISEASES
51124  |  IER3IP1  |  DISEASES
3568  |  IL5RA  |  DISEASES
3656  |  IRAK2  |  DISEASES
10468  |  FST  |  DISEASES
2922  |  GRP  |  DISEASES
59340  |  HRH4  |  DISEASES
187  |  APLNR  |  DISEASES
301  |  ANXA1  |  DISEASES
967  |  CD63  |  DISEASES
116540  |  MRPL53  |  DISEASES
80896  |  NPL  |  DISEASES
10154  |  PLXNC1  |  DISEASES
3569  |  IL6  |  DISEASES
313  |  AOAH  |  DISEASES
56300  |  IL36G  |  DISEASES
3557  |  IL1RN  |  DISEASES
5004  |  ORM1  |  DISEASES
5082  |  PDCL  |  DISEASES
5168  |  ENPP2  |  DISEASES
79139  |  DERL1  |  DISEASES
3442  |  IFNA5  |  DISEASES
6366  |  CCL21  |  DISEASES
10850  |  CCL27  |  DISEASES
1208  |  CLPS  |  DISEASES
51439  |  FAM8A1  |  DISEASES
83888  |  FGFBP2  |  DISEASES
7097  |  TLR2  |  DISEASES
2615  |  LRRC32  |  DISEASES
51050  |  PI15  |  DISEASES
4316  |  MMP7  |  DISEASES
102  |  ADAM10  |  DISEASES
1559  |  CYP2C9  |  DISEASES
9360  |  PPIG  |  DISEASES
11213  |  IRAK3  |  DISEASES
4069  |  LYZ  |  DISEASES
1182  |  CLCN3  |  DISEASES
6095  |  RORA  |  DISEASES
1535  |  CYBA  |  DISEASES
6433  |  SFSWAP  |  DISEASES
217  |  ALDH2  |  DISEASES
59341  |  TRPV4  |  DISEASES
9904  |  RBM19  |  DISEASES
999  |  CDH1  |  DISEASES
384  |  ARG2  |  DISEASES
79875  |  THSD4  |  DISEASES
8482  |  SEMA7A  |  DISEASES
4016  |  LOXL1  |  DISEASES
9252  |  RPS6KA5  |  DISEASES
4092  |  SMAD7  |  DISEASES
4087  |  SMAD2  |  DISEASES
7434  |  VIPR2  |  DISEASES
8989  |  TRPA1  |  DISEASES
7528  |  YY1  |  DISEASES
4025  |  LPO  |  DISEASES
4591  |  TRIM37  |  DISEASES
1387  |  CREBBP  |  DISEASES
6521  |  SLC4A1  |  DISEASES
83716  |  CRISPLD2  |  DISEASES
495  |  ATP4A  |  DISEASES
5465  |  PPARA  |  DISEASES
7077  |  TIMP2  |  DISEASES
25939  |  SAMHD1  |  DISEASES
3783  |  KCNN4  |  DISEASES
5595  |  MAPK3  |  DISEASES
22858  |  ICK  |  DISEASES
3682  |  ITGAE  |  DISEASES
10096  |  ACTR3  |  DISEASES
2033  |  EP300  |  DISEASES
50507  |  NOX4  |  DISEASES
27178  |  IL37  |  DISEASES
3552  |  IL1A  |  DISEASES
3553  |  IL1B  |  DISEASES
8726  |  EED  |  DISEASES
23476  |  BRD4  |  DISEASES
9466  |  IL27RA  |  DISEASES
54414  |  SIAE  |  DISEASES
3933  |  LCN1  |  DISEASES
1991  |  ELANE  |  DISEASES
64135  |  IFIH1  |  DISEASES
6403  |  SELP  |  DISEASES
7301  |  TYRO3  |  DISEASES
3574  |  IL7  |  DISEASES
10578  |  GNLY  |  DISEASES
3791  |  KDR  |  DISEASES
943  |  TNFRSF8  |  DISEASES
51192  |  CKLF  |  DISEASES
2208  |  FCER2  |  DISEASES
941  |  CD80  |  DISEASES
7294  |  TXK  |  DISEASES
10144  |  FAM13A  |  DISEASES
374  |  AREG  |  DISEASES
59067  |  IL21  |  DISEASES
2247  |  FGF2  |  DISEASES
3589  |  IL11  |  DISEASES
1356  |  CP  |  DISEASES
5709  |  PSMD3  |  DISEASES
6774  |  STAT3  |  DISEASES
2255  |  FGF10  |  DISEASES
5443  |  POMC  |  DISEASES
8626  |  TP63  |  DISEASES
7297  |  TYK2  |  DISEASES
3383  |  ICAM1  |  DISEASES
3827  |  KNG1  |  DISEASES
1462  |  VCAN  |  DISEASES
1950  |  EGF  |  DISEASES
6722  |  SRF  |  DISEASES
256076  |  COL6A5  |  DISEASES
5423  |  POLB  |  DISEASES
4258  |  MGST2  |  DISEASES
286  |  ANK1  |  DISEASES
5172  |  SLC26A4  |  DISEASES
55749  |  CCAR1  |  DISEASES
5286  |  PIK3C2A  |  DISEASES
3373  |  HYAL1  |  DISEASES
4060  |  LUM  |  DISEASES
3695  |  ITGB7  |  DISEASES
60314  |  C12orf10  |  DISEASES
8477  |  GPR65  |  DISEASES
90050  |  FAM181A  |  DISEASES
3067  |  HDC  |  DISEASES
597  |  BCL2A1  |  DISEASES
3687  |  ITGAX  |  DISEASES
64180  |  DPEP3  |  DISEASES
409  |  ARRB2  |  DISEASES
7157  |  TP53  |  DISEASES
5409  |  PNMT  |  DISEASES
207  |  AKT1  |  DISEASES
1762  |  DMWD  |  DISEASES
11006  |  LILRB4  |  DISEASES
5141  |  PDE4A  |  DISEASES
2212  |  FCGR2A  |  DISEASES
5298  |  PI4KB  |  DISEASES
2052  |  EPHX1  |  DISEASES
5972  |  REN  |  DISEASES
805  |  CALM2  |  DISEASES
2840  |  GPR17  |  DISEASES
23671  |  TMEFF2  |  DISEASES
7220  |  TRPC1  |  DISEASES
3001  |  GZMA  |  DISEASES
5295  |  PIK3R1  |  DISEASES
51397  |  COMMD10  |  DISEASES
3578  |  IL9  |  DISEASES
91937  |  TIMD4  |  DISEASES
1956  |  EGFR  |  DISEASES
139818  |  DOCK11  |  DISEASES
80005  |  DOCK5  |  DISEASES
1392  |  CRH  |  DISEASES
3439  |  IFNA1  |  DISEASES
4915  |  NTRK2  |  DISEASES
3934  |  LCN2  |  DISEASES
4851  |  NOTCH1  |  DISEASES
80013  |  FAM188A  |  DISEASES
133  |  ADM  |  DISEASES
7356  |  SCGB1A1  |  DISEASES
932  |  MS4A3  |  DISEASES
2206  |  MS4A2  |  DISEASES
6876  |  TAGLN  |  DISEASES
10398  |  MYL9  |  DISEASES
10435  |  CDC42EP2  |  DISEASES
3176  |  HNMT  |  DISEASES
3606  |  IL18  |  DISEASES
7082  |  TJP1  |  DISEASES
144423  |  GLT1D1  |  DISEASES
23704  |  KCNE4  |  DISEASES
7292  |  TNFSF4  |  DISEASES
57105  |  CYSLTR2  |  DISEASES
2321  |  FLT1  |  DISEASES
6317  |  SERPINB3  |  DISEASES
23643  |  LY96  |  DISEASES
231  |  AKR1B1  |  DISEASES
10  |  NAT2  |  DISEASES
10538  |  BATF  |  DISEASES
27163  |  NAAA  |  DISEASES
5097  |  PCDH1  |  DISEASES
123803  |  NTAN1  |  DISEASES
5468  |  PPARG  |  DISEASES
3815  |  KIT  |  DISEASES
55540  |  IL17RB  |  DISEASES
26060  |  APPL1  |  DISEASES
5291  |  PIK3CB  |  DISEASES
8365  |  HIST1H4H  |  DISEASES
11309  |  SLCO2B1  |  DISEASES
2207  |  FCER1G  |  DISEASES
3460  |  IFNGR2  |  DISEASES
1636  |  ACE  |  DISEASES
5739  |  PTGIR  |  DISEASES
808  |  CALM3  |  DISEASES
7032  |  TFF2  |  DISEASES
326  |  AIRE  |  DISEASES
643  |  CXCR5  |  DISEASES
729230  |  CCR2  |  DISEASES
1234  |  CCR5  |  DISEASES
5731  |  PTGER1  |  DISEASES
4056  |  LTC4S  |  DISEASES
3046  |  HBE1  |  DISEASES
6352  |  CCL5  |  DISEASES
6359  |  CCL15  |  DISEASES
6777  |  STAT5B  |  DISEASES
362  |  AQP5  |  DISEASES
246  |  ALOX15  |  DISEASES
260429  |  PRSS33  |  DISEASES
115  |  ADCY9  |  DISEASES
7412  |  VCAM1  |  DISEASES
2215  |  FCGR3B  |  DISEASES
91461  |  PKDCC  |  DISEASES
27306  |  HPGDS  |  DISEASES
10461  |  MERTK  |  DISEASES
11167  |  FSTL1  |  DISEASES
3577  |  CXCR1  |  DISEASES
84666  |  RETNLB  |  DISEASES
152185  |  SPICE1  |  DISEASES
213  |  ALB  |  DISEASES
84818  |  IL17RC  |  DISEASES
2921  |  CXCL3  |  DISEASES
6374  |  CXCL5  |  DISEASES
5473  |  PPBP  |  DISEASES
5196  |  PF4  |  DISEASES
1359  |  CPA3  |  DISEASES
1230  |  CCR1  |  DISEASES
6010  |  RHO  |  DISEASES
128  |  ADH5  |  DISEASES
308  |  ANXA5  |  DISEASES
3600  |  IL15  |  DISEASES
3673  |  ITGA2  |  DISEASES
651746  |  ANKRD33B  |  DISEASES
2150  |  F2RL1  |  DISEASES
4724  |  NDUFS4  |  DISEASES
117156  |  SCGB3A2  |  DISEASES
7098  |  TLR3  |  DISEASES
3562  |  IL3  |  DISEASES
1437  |  CSF2  |  DISEASES
1672  |  DEFB1  |  DISEASES
4846  |  NOS3  |  DISEASES
4783  |  NFIL3  |  DISEASES
115825  |  WDFY2  |  DISEASES
139081  |  MAGEC3  |  DISEASES
27199  |  OXGR1  |  DISEASES
9317  |  PTER  |  DISEASES
5896  |  RAG1  |  DISEASES
5055  |  SERPINB2  |  DISEASES
4314  |  MMP3  |  DISEASES
89927  |  C16orf45  |  DISEASES
6866  |  TAC3  |  DISEASES
6778  |  STAT6  |  DISEASES
6632  |  SNRPD1  |  DISEASES
23102  |  TBC1D2B  |  DISEASES
64127  |  NOD2  |  DISEASES
6786  |  STIM1  |  DISEASES
148170  |  CDC42EP5  |  DISEASES
94274  |  PPP1R14A  |  DISEASES
4909  |  NTF4  |  DISEASES
3816  |  KLK1  |  DISEASES
284110  |  GSDMA  |  DISEASES
5724  |  PTAFR  |  DISEASES
4589  |  MUC7  |  DISEASES
719  |  C3AR1  |  DISEASES
6356  |  CCL11  |  DISEASES
6037  |  RNASE3  |  DISEASES
8460  |  TPST1  |  DISEASES
5604  |  MAP2K1  |  DISEASES
64581  |  CLEC7A  |  DISEASES
3479  |  IGF1  |  DISEASES
2357  |  FPR1  |  DISEASES
5734  |  PTGER4  |  DISEASES
3603  |  IL16  |  DISEASES
3308  |  HSPA4  |  DISEASES
140738  |  TMEM37  |  DISEASES
9723  |  SEMA3E  |  DISEASES
3689  |  ITGB2  |  DISEASES
59350  |  RXFP1  |  DISEASES
6036  |  RNASE2  |  DISEASES
6870  |  TACR3  |  DISEASES
3688  |  ITGB1  |  DISEASES
8988  |  HSPB3  |  DISEASES
5729  |  PTGDR  |  DISEASES
84640  |  USP38  |  DISEASES
6869  |  TACR1  |  DISEASES
1673  |  DEFB4A  |  DISEASES
1493  |  CTLA4  |  DISEASES
3171  |  FOXA3  |  DISEASES
136  |  ADORA2B  |  DISEASES
1448  |  CSN3  |  DISEASES
94103  |  ORMDL3  |  DISEASES
3596  |  IL13  |  DISEASES
9655  |  SOCS5  |  DISEASES
11141  |  IL1RAPL1  |  DISEASES
154  |  ADRB2  |  DISEASES
1901  |  S1PR1  |  DISEASES
1051  |  CEBPB  |  DISEASES
3627  |  CXCL10  |  DISEASES
5066  |  PAM  |  DISEASES
3575  |  IL7R  |  DISEASES
2353  |  FOS  |  DISEASES
83886  |  PRSS27  |  DISEASES
1128  |  CHRM1  |  DISEASES
125  |  ADH1B  |  DISEASES
147  |  ADRA1B  |  DISEASES
6373  |  CXCL11  |  DISEASES
3037  |  HAS2  |  DISEASES
9451  |  EIF2AK3  |  DISEASES
64805  |  P2RY12  |  DISEASES
126669  |  SHE  |  DISEASES
1241  |  LTB4R  |  DISEASES
624  |  BDKRB2  |  DISEASES
54205  |  CYCS  |  DISEASES
10855  |  HPSE  |  DISEASES
695  |  BTK  |  DISEASES
9934  |  P2RY14  |  DISEASES
2147  |  F2  |  DISEASES
134  |  ADORA1  |  DISEASES
5897  |  RAG2  |  DISEASES
6363  |  CCL19  |  DISEASES
81793  |  TLR10  |  DISEASES
5340  |  PLG  |  DISEASES
9690  |  UBE3C  |  DISEASES
1657  |  DMXL1  |  DISEASES
5031  |  P2RY6  |  DISEASES
116113  |  FOXP4  |  DISEASES
947  |  CD34  |  DISEASES
3661  |  IRF3  |  DISEASES
26512  |  INTS6  |  DISEASES
5029  |  P2RY2  |  DISEASES
9092  |  SART1  |  DISEASES
147183  |  KRT25  |  DISEASES
836  |  CASP3  |  DISEASES
2944  |  GSTM1  |  DISEASES
84868  |  HAVCR2  |  DISEASES
5553  |  PRG2  |  DISEASES
5319  |  PLA2G1B  |  DISEASES
133522  |  PPARGC1B  |  DISEASES
3952  |  LEP  |  DISEASES
4281  |  MID1  |  DISEASES
4793  |  NFKBIB  |  DISEASES
3184  |  HNRNPD  |  DISEASES
64096  |  GFRA4  |  DISEASES
5198  |  PFAS  |  DISEASES
8877  |  SPHK1  |  DISEASES
57101  |  ANO2  |  DISEASES
1831  |  TSC22D3  |  DISEASES
54472  |  TOLLIP  |  DISEASES
3556  |  IL1RAP  |  DISEASES
285  |  ANGPT2  |  DISEASES
1909  |  EDNRA  |  DISEASES
30835  |  CD209  |  DISEASES
3170  |  FOXA2  |  DISEASES
6440  |  SFTPC  |  DISEASES
8560  |  DEGS1  |  DISEASES
53346  |  TM6SF1  |  DISEASES
9377  |  COX5A  |  DISEASES
53905  |  DUOX1  |  DISEASES
4684  |  NCAM1  |  DISEASES
56676  |  ASCL3  |  DISEASES
55076  |  TMEM45A  |  DISEASES
8490  |  RGS5  |  DISEASES
91662  |  NLRP12  |  DISEASES
29851  |  ICOS  |  DISEASES
3579  |  CXCR2  |  DISEASES
3183  |  HNRNPC  |  DISEASES
1728  |  NQO1  |  DISEASES
1129  |  CHRM2  |  DISEASES
80381  |  CD276  |  DISEASES
9520  |  NPEPPS  |  DISEASES
8727  |  CTNNAL1  |  DISEASES
10938  |  EHD1  |  DISEASES
9370  |  ADIPOQ  |  DISEASES
23765  |  IL17RA  |  DISEASES
27181  |  SIGLEC8  |  DISEASES
6863  |  TAC1  |  DISEASES
149233  |  IL23R  |  DISEASES
131566  |  DCBLD2  |  DISEASES
10611  |  PDLIM5  |  DISEASES
23212  |  RRS1  |  DISEASES
3039  |  HBA1  |  DISEASES
4312  |  MMP1  |  DISEASES
11336  |  EXOC3  |  DISEASES
55600  |  ITLN1  |  DISEASES
2302  |  FOXJ1  |  DISEASES
79054  |  TRPM8  |  DISEASES
2  |  A2M  |  DISEASES
9235  |  IL32  |  DISEASES
26999  |  CYFIP2  |  DISEASES
222256  |  CDHR3  |  DISEASES
9622  |  KLK4  |  DISEASES
788  |  SLC25A20  |  DISEASES
1237  |  CCR8  |  DISEASES
83852  |  SETDB2  |  DISEASES
3052  |  HCCS  |  DISEASES
64327  |  LMBR1  |  DISEASES
161882  |  ZFPM1  |  DISEASES
94101  |  ORMDL1  |  DISEASES
6097  |  RORC  |  DISEASES
4094  |  MAF  |  DISEASES
2318  |  FLNC  |  DISEASES
7433  |  VIPR1  |  DISEASES
4843  |  NOS2  |  DISEASES
633  |  BGN  |  DISEASES
4991  |  OR1D2  |  DISEASES
4772  |  NFATC1  |  DISEASES
3563  |  IL3RA  |  DISEASES
64806  |  IL25  |  DISEASES
8784  |  TNFRSF18  |  DISEASES
84876  |  ORAI1  |  DISEASES
2865  |  FFAR3  |  DISEASES
58491  |  ZNF71  |  DISEASES
200504  |  GKN2  |  DISEASES
50616  |  IL22  |  DISEASES
3665  |  IRF7  |  DISEASES
8651  |  SOCS1  |  DISEASES
84206  |  MEX3B  |  DISEASES
9021  |  SOCS3  |  DISEASES
28955  |  DEXI  |  DISEASES
7850  |  IL1R2  |  DISEASES
83482  |  SCRT1  |  DISEASES
6401  |  SELE  |  DISEASES
796  |  CALCA  |  DISEASES
942  |  CD86  |  DISEASES
5142  |  PDE4B  |  DISEASES
5367  |  PMCH  |  DISEASES
113179  |  ADAT3  |  DISEASES
10227  |  MFSD10  |  DISEASES
11251  |  PTGDR2  |  DISEASES
4088  |  SMAD3  |  DISEASES
59307  |  SIGIRR  |  DISEASES
117194  |  MRGPRX2  |  DISEASES
151888  |  BTLA  |  DISEASES
255061  |  TAC4  |  DISEASES
2152  |  F3  |  DISEASES
120227  |  CYP2R1  |  DISEASES
10810  |  WASF3  |  DISEASES
124626  |  ZPBP2  |  DISEASES
2938  |  GSTA1  |  DISEASES
3607  |  FOXK2  |  DISEASES
8856  |  NR1I2  |  DISEASES
5025  |  P2RX4  |  DISEASES
135  |  ADORA2A  |  DISEASES
81608  |  FIP1L1  |  DISEASES
283  |  ANG  |  DISEASES
1908  |  EDN3  |  DISEASES
114548  |  NLRP3  |  DISEASES
112744  |  IL17F  |  DISEASES
1551  |  CYP3A7  |  DISEASES
4842  |  NOS1  |  DISEASES
10011  |  SRA1  |  DISEASES
64386  |  MMP25  |  DISEASES
3932  |  LCK  |  DISEASES
7189  |  TRAF6  |  DISEASES
1576  |  CYP3A4  |  DISEASES
3363  |  HTR7  |  DISEASES
3091  |  HIF1A  |  DISEASES
2289  |  FKBP5  |  DISEASES
23236  |  PLCB1  |  DISEASES
23580  |  CDC42EP4  |  DISEASES
51337  |  THEM6  |  DISEASES
857  |  CAV1  |  DISEASES
54878  |  DPP8  |  DISEASES
3117  |  HLA-DQA1  |  DISEASES
1429  |  CRYZ  |  DISEASES
85480  |  TSLP  |  DISEASES
84545  |  MRPL43  |  DISEASES
3329  |  HSPD1  |  DISEASES
7100  |  TLR5  |  DISEASES
2358  |  FPR2  |  DISEASES
115362  |  GBP5  |  DISEASES
6609  |  SMPD1  |  DISEASES
6701  |  SPRR2B  |  DISEASES
7225  |  TRPC6  |  DISEASES
6614  |  SIGLEC1  |  DISEASES
6776  |  STAT5A  |  DISEASES
51094  |  ADIPOR1  |  DISEASES
27159  |  CHIA  |  DISEASES
1544  |  CYP1A2  |  DISEASES
9588  |  PRDX6  |  DISEASES
5132  |  PDC  |  DISEASES
1508  |  CTSB  |  DISEASES
6590  |  SLPI  |  DISEASES
9536  |  PTGES  |  DISEASES
11255  |  HRH3  |  DISEASES
108  |  ADCY2  |  DISEASES
57515  |  SERINC1  |  DISEASES
29949  |  IL19  |  DISEASES
121642  |  ALKBH2  |  DISEASES
3146  |  HMGB1  |  DISEASES
3716  |  JAK1  |  DISEASES
8360  |  HIST1H4D  |  DISEASES
9474  |  ATG5  |  DISEASES
6318  |  SERPINB4  |  DISEASES
7177  |  TPSAB1  |  DISEASES
22835  |  ZFP30  |  DISEASES
10252  |  SPRY1  |  DISEASES
3455  |  IFNAR2  |  DISEASES
3605  |  IL17A  |  DISEASES
53827  |  FXYD5  |  DISEASES
1499  |  CTNNB1  |  DISEASES
22806  |  IKZF3  |  DISEASES
147199  |  SCGB1C1  |  DISEASES
55972  |  SLC25A40  |  DISEASES
119391  |  GSTO2  |  DISEASES
3516  |  RBPJ  |  DISEASES
5144  |  PDE4D  |  DISEASES
387712  |  ENO4  |  DISEASES
538  |  ATP7A  |  DISEASES
302  |  ANXA2  |  DISEASES
2879  |  GPX4  |  DISEASES
51297  |  BPIFA1  |  DISEASES
8294  |  HIST1H4I  |  DISEASES
23587  |  ELP5  |  DISEASES
2534  |  FYN  |  DISEASES
2335  |  FN1  |  DISEASES
8654  |  PDE5A  |  DISEASES
64218  |  SEMA4A  |  DISEASES
8363  |  HIST1H4J  |  DISEASES
728  |  C5AR1  |  DISEASES
100506658  |  OCLN  |  DISEASES
55107  |  ANO1  |  DISEASES
26112  |  CCDC69  |  DISEASES
5143  |  PDE4C  |  DISEASES
2204  |  FCAR  |  DISEASES
8764  |  TNFRSF14  |  DISEASES
355  |  FAS  |  DISEASES
5265  |  SERPINA1  |  DISEASES
3240  |  HP  |  DISEASES
8368  |  HIST1H4L  |  DISEASES
80332  |  ADAM33  |  DISEASES
5733  |  PTGER3  |  DISEASES
3683  |  ITGAL  |  DISEASES
8794  |  TNFRSF10C  |  DISEASES
801  |  CALM1  |  DISEASES
79602  |  ADIPOR2  |  DISEASES
57209  |  ZNF248  |  DISEASES
60  |  ACTB  |  DISEASES
2181  |  ACSL3  |  DISEASES
55691  |  FRMD4A  |  DISEASES
8362  |  HIST1H4K  |  DISEASES
10803  |  CCR9  |  DISEASES
5169  |  ENPP3  |  DISEASES
26151  |  NAT9  |  DISEASES
121504  |  HIST4H4  |  DISEASES
6714  |  SRC  |  DISEASES
1524  |  CX3CR1  |  DISEASES
6775  |  STAT4  |  DISEASES
841  |  CASP8  |  DISEASES
2213  |  FCGR2B  |  DISEASES
2526  |  FUT4  |  DISEASES
6364  |  CCL20  |  DISEASES
4217  |  MAP3K5  |  DISEASES
9332  |  CD163  |  DISEASES
5294  |  PIK3CG  |  DISEASES
5336  |  PLCG2  |  DISEASES
8936  |  WASF1  |  DISEASES
3635  |  INPP5D  |  DISEASES
387129  |  NPSR1  |  DISEASES
11005  |  SPINK5  |  DISEASES
8359  |  HIST1H4A  |  DISEASES
1201  |  CLN3  |  DISEASES
3123  |  HLA-DRB1  |  DISEASES
79947  |  DHDDS  |  DISEASES
7037  |  TFRC  |  DISEASES
4638  |  MYLK  |  DISEASES
55876  |  GSDMB  |  DISEASES
3135  |  HLA-G  |  DISEASES
5599  |  MAPK8  |  DISEASES
8367  |  HIST1H4E  |  DISEASES
4311  |  MME  |  DISEASES
1803  |  DPP4  |  DISEASES
54106  |  TLR9  |  DISEASES
56891  |  LGALS14  |  DISEASES
23560  |  GTPBP4  |  DISEASES
100049587  |  SIGLEC14  |  DISEASES
6772  |  STAT1  |  DISEASES
2475  |  MTOR  |  DISEASES
257202  |  GPX6  |  DISEASES
5742  |  PTGS1  |  DISEASES
10724  |  MGEA5  |  DISEASES
4283  |  CXCL9  |  DISEASES
7096  |  TLR1  |  DISEASES
56670  |  SUCNR1  |  DISEASES
23038  |  WDTC1  |  DISEASES
7052  |  TGM2  |  DISEASES
159  |  ADSS  |  DISEASES
23596  |  OPN3  |  DISEASES
58  |  ACTA1  |  DISEASES
142  |  PARP1  |  DISEASES
3142  |  HLX  |  DISEASES
2058  |  EPRS  |  DISEASES
7042  |  TGFB2  |  DISEASES
1378  |  CR1  |  DISEASES
1380  |  CR2  |  DISEASES
1118  |  CHIT1  |  DISEASES
7432  |  VIP  |  DISEASES
252839  |  TMEM9  |  DISEASES
5788  |  PTPRC  |  DISEASES
163486  |  DENND1B  |  DISEASES
5321  |  PLA2G4A  |  DISEASES
5743  |  PTGS2  |  DISEASES
356  |  FASLG  |  DISEASES
3459  |  IFNGR1  |  DISEASES
1805  |  DPT  |  DISEASES
6375  |  XCL1  |  DISEASES
4259  |  MGST3  |  DISEASES
22926  |  ATF6  |  DISEASES
11266  |  DUSP12  |  DISEASES
2214  |  FCGR3A  |  DISEASES
1490  |  CTGF  |  DISEASES
4720  |  NDUFS2  |  DISEASES
7391  |  USF1  |  DISEASES
142683  |  ITLN2  |  DISEASES
962  |  CD48  |  DISEASES
383  |  ARG1  |  DISEASES
2205  |  FCER1A  |  DISEASES
149628  |  PYHIN1  |  DISEASES
911  |  CD1C  |  DISEASES
912  |  CD1D  |  DISEASES
632  |  BGLAP  |  DISEASES
339403  |  RXFP4  |  DISEASES
4582  |  MUC1  |  DISEASES
3570  |  IL6R  |  DISEASES
4082  |  MARCKS  |  DISEASES
8038  |  ADAM12  |  DISEASES
4881  |  NPR1  |  DISEASES
6283  |  S100A12  |  DISEASES
149018  |  LELP1  |  DISEASES
2312  |  FLG  |  DISEASES
7062  |  TCHH  |  DISEASES
117145  |  THEM4  |  DISEASES
79626  |  TNFAIP8L2  |  DISEASES
1520  |  CTSS  |  DISEASES
554313  |  HIST2H4B  |  DISEASES
8370  |  HIST2H4A  |  DISEASES
2209  |  FCGR1A  |  DISEASES
153  |  ADRB1  |  DISEASES
914  |  CD2  |  DISEASES
55356  |  SLC22A15  |  DISEASES
4803  |  NGF  |  DISEASES
140  |  ADORA3  |  DISEASES
1117  |  CHI3L2  |  DISEASES
2316  |  FLNA  |  DISEASES
3654  |  IRAK1  |  DISEASES
1137  |  CHRNA4  |  DISEASES
1369  |  CPN1  |  DISEASES
22802  |  CLCA4  |  DISEASES
9635  |  CLCA2  |  DISEASES
2258  |  FGF13  |  DISEASES
959  |  CD40LG  |  DISEASES
2778  |  GNAS  |  DISEASES
6005  |  RHAG  |  DISEASES
953  |  ENTPD1  |  DISEASES
3725  |  JUN  |  DISEASES
1557  |  CYP2C19  |  DISEASES
6342  |  SCP2  |  DISEASES
3597  |  IL13RA1  |  DISEASES
64756  |  ATPAF1  |  DISEASES
5728  |  PTEN  |  DISEASES
5900  |  RALGDS  |  DISEASES
7422  |  VEGFA  |  DISEASES
27069  |  GHITM  |  DISEASES
958  |  CD40  |  DISEASES
6441  |  SFTPD  |  DISEASES
729238  |  SFTPA2  |  DISEASES
4318  |  MMP9  |  DISEASES
9670  |  IPO13  |  DISEASES
1907  |  EDN2  |  DISEASES
441509  |  GLRA4  |  DISEASES
64744  |  SMAP2  |  DISEASES
10695  |  CNPY3  |  DISEASES
100  |  ADA  |  DISEASES
27095  |  TRAPPC3  |  DISEASES
10800  |  CYSLTR1  |  DISEASES
6865  |  TACR2  |  DISEASES
5292  |  PIM1  |  DISEASES
3065  |  HDAC1  |  DISEASES
200081  |  TXLNA  |  DISEASES
2833  |  CXCR3  |  DISEASES
553115  |  PEF1  |  DISEASES
29119  |  CTNNA3  |  DISEASES
84890  |  ADO  |  DISEASES
54797  |  MED18  |  DISEASES
26190  |  FBXW2  |  DISEASES
4153  |  MBL2  |  DISEASES
7099  |  TLR4  |  DISEASES
25803  |  SPDEF  |  DISEASES
285180  |  RUFY4  |  DISEASES
3561  |  IL2RG  |  DISEASES
246184  |  CDC26  |  DISEASES
240  |  ALOX5  |  DISEASES
7295  |  TXN  |  DISEASES
5030  |  P2RY4  |  DISEASES
9277  |  WDR46  |  DISEASES
3339  |  HSPG2  |  DISEASES
3118  |  HLA-DQA2  |  DISEASES
3127  |  HLA-DRB5  |  DISEASES
7046  |  TGFBR1  |  DISEASES
177  |  AGER  |  DISEASES
5320  |  PLA2G2A  |  DISEASES
4686  |  NCBP1  |  DISEASES
3376  |  IARS  |  DISEASES
6850  |  SYK  |  DISEASES
23013  |  SPEN  |  DISEASES
3055  |  HCK  |  DISEASES
10673  |  TNFSF13B  |  DISEASES
50943  |  FOXP3  |  DISEASES
87769  |  GGACT  |  DISEASES
7133  |  TNFRSF1B  |  DISEASES
54520  |  CCDC93  |  DISEASES
4878  |  NPPA  |  DISEASES
7091  |  TLE4  |  DISEASES
2623  |  GATA1  |  DISEASES
3105  |  HLA-A  |  DISEASES
386653  |  IL31  |  DISEASES
1325  |  CORT  |  DISEASES
7056  |  THBD  |  DISEASES
1910  |  EDNRB  |  DISEASES
3274  |  HRH2  |  DISEASES
5293  |  PIK3CD  |  DISEASES
8366  |  HIST1H4B  |  DISEASES
92675  |  DTD1  |  DISEASES
54206  |  ERRFI1  |  DISEASES
3604  |  TNFRSF9  |  DISEASES
8361  |  HIST1H4F  |  DISEASES
8718  |  TNFRSF25  |  DISEASES
8364  |  HIST1H4C  |  DISEASES
51131  |  PHF11  |  DISEASES
6354  |  CCL7  |  DISEASES
1536  |  CYBB  |  DISEASES
165140  |  OXER1  |  DISEASES
11127  |  KIF3A  |  DISEASES
646480  |  FABP9  |  DISEASES
201229  |  LYRM9  |  DISEASES
9308  |  CD83  |  DISEASES
7293  |  TNFRSF4  |  DISEASES
5212  |  VIT  |  DISEASES
2625  |  GATA3  |  DISEASES
1906  |  EDN1  |  DISEASES
7222  |  TRPC3  |  DISEASES
1543  |  CYP1A1  |  DISEASES
10631  |  POSTN  |  DISEASES
23586  |  DDX58  |  DISEASES
3559  |  IL2RA  |  DISEASES
7010  |  TEK  |  DISEASES
247  |  ALOX15B  |  DISEASES
3456  |  IFNB1  |  DISEASES
551  |  AVP  |  DISEASES
119679  |  OR52J3  |  DISEASES
241  |  ALOX5AP  |  DISEASES
51284  |  TLR7  |  DISEASES
728340  |  GTF2H2C  |  DISEASES
1992  |  SERPINB1  |  DISEASES
3662  |  IRF4  |  DISEASES
9189  |  ZBED1  |  DISEASES
90865  |  IL33  |  DISEASES
7006  |  TEC  |  DISEASES
64109  |  CRLF2  |  DISEASES
29126  |  CD274  |  DISEASES
3717  |  JAK2  |  DISEASES
23464  |  GCAT  |  DISEASES
5555  |  PRH2  |  DISEASES
10333  |  TLR6  |  DISEASES
91543  |  RSAD2  |  DISEASES
26524  |  LATS2  |  DISEASES
9467  |  SH3BP5  |  DISEASES
2878  |  GPX3  |  DISEASES
50506  |  DUOX2  |  DISEASES
238  |  ALK  |  DISEASES
10411  |  RAPGEF3  |  DISEASES
5799  |  PTPRN2  |  DISEASES
2877  |  GPX2  |  DISEASES
440193  |  CCDC88C  |  DISEASES
2524  |  FUT2  |  DISEASES
147906  |  DACT3  |  DISEASES
12  |  SERPINA3  |  DISEASES
122509  |  IFI27L1  |  DISEASES
57628  |  DPP10  |  DISEASES
338699  |  ANKRD42  |  DISEASES
26269  |  FBXO8  |  DISEASES
6439  |  SFTPB  |  DISEASES
64174  |  DPEP2  |  DISEASES
5091  |  PC  |  DISEASES
6152  |  RPL24  |  DISEASES
55773  |  TBC1D23  |  DISEASES
5627  |  PROS1  |  DISEASES
51520  |  LARS  |  DISEASES
9560  |  CCL4L2  |  DISEASES
6355  |  CCL8  |  DISEASES
6696  |  SPP1  |  DISEASES
3122  |  HLA-DRA  |  DISEASES
27040  |  LAT  |  DISEASES
3965  |  LGALS9  |  DISEASES
2919  |  CXCL1  |  DISEASES
6387  |  CXCL12  |  DISEASES
4773  |  NFATC2  |  DISEASES
117  |  ADCYAP1R1  |  DISEASES
4629  |  MYH11  |  DISEASES
84807  |  NFKBID  |  DISEASES
3676  |  ITGA4  |  DISEASES
3269  |  HRH1  |  DISEASES
4780  |  NFE2L2  |  DISEASES
11069  |  RAPGEF4  |  DISEASES
4689  |  NCF4  |  DISEASES
4703  |  NEB  |  DISEASES
80380  |  PDCD1LG2  |  DISEASES
5609  |  MAP2K7  |  DISEASES
594857  |  NPS  |  DISEASES
1394  |  CRHR1  |  DISEASES
2687  |  GGT5  |  DISEASES
2950  |  GSTP1  |  DISEASES
3119  |  HLA-DQB1  |  DISEASES
29965  |  CDIP1  |  DISEASES
7442  |  TRPV1  |  DISEASES
6093  |  ROCK1  |  DISEASES
386677  |  KRTAP10-1  |  DISEASES
5970  |  RELA  |  DISEASES
23308  |  ICOSLG  |  DISEASES
4660  |  PPP1R12B  |  DISEASES
9170  |  LPAR2  |  DISEASES
1994  |  ELAVL1  |  DISEASES
5150  |  PDE7A  |  DISEASES
3778  |  KCNMA1  |  DISEASES
7018  |  TF  |  DISEASES
50489  |  CD207  |  DISEASES
6295  |  SAG  |  DISEASES
7852  |  CXCR4  |  DISEASES
501  |  ALDH7A1  |  DISEASES
3267  |  AGFG1  |  DISEASES
65986  |  ZBTB10  |  DISEASES
2641  |  GCG  |  DISEASES
1385  |  CREB1  |  DISEASES
3384  |  ICAM2  |  DISEASES
255743  |  NPNT  |  DISEASES
5601  |  MAPK9  |  DISEASES
3120  |  HLA-DQB2  |  DISEASES
51135  |  IRAK4  |  DISEASES
10551  |  AGR2  |  DISEASES
3718  |  JAK3  |  DISEASES
2880  |  GPX5  |  DISEASES
94026  |  POM121L2  |  DISEASES
1638  |  DCT  |  DISEASES
6915  |  TBXA2R  |  DISEASES
8399  |  PLA2G10  |  DISEASES
1438  |  CSF2RA  |  DISEASES
283463  |  MUC19  |  DISEASES
23705  |  CADM1  |  DISEASES
10163  |  WASF2  |  DISEASES
720  |  C4A  |  DISEASES
79935  |  CNTD2  |  DISEASES
4908  |  NTF3  |  DISEASES
117579  |  RLN3  |  DISEASES
960  |  CD44  |  DISEASES
3702  |  ITK  |  DISEASES
7124  |  TNF  |  DISEASES
387  |  RHOA  |  DISEASES
4615  |  MYD88  |  DISEASES
5706  |  PSMC6  |  DISEASES
3594  |  IL12RB1  |  DISEASES
4049  |  LTA  |  DISEASES
9278  |  ZBTB22  |  DISEASES
388372  |  CCL4L1  |  DISEASES
84148  |  KAT8  |  DISEASES
3276  |  PRMT1  |  DISEASES
2876  |  GPX1  |  DISEASES
3115  |  HLA-DPB1  |  DISEASES
81704  |  DOCK8  |  DISEASES
5578  |  PRKCA  |  DISEASES
6349  |  CCL3L1  |  DISEASES
6358  |  CCL14  |  DISEASES
1154  |  CISH  |  DISEASES
408  |  ARRB1  |  DISEASES
387640  |  SKIDA1  |  DISEASES
834  |  CASP1  |  DISEASES
4050  |  LTB  |  DISEASES
92293  |  TMEM132C  |  DISEASES
1028  |  CDKN1C  |  DISEASES
3586  |  IL10  |  DISEASES
5554  |  PRH1  |  DISEASES
627  |  BDNF  |  DISEASES
55250  |  ELP2  |  DISEASES
4583  |  MUC2  |  DISEASES
2859  |  GPR35  |  DISEASES
165631  |  PARP15  |  DISEASES
4585  |  MUC4  |  DISEASES
57620  |  STIM2  |  DISEASES
374308  |  PTCHD3  |  DISEASES
5478  |  PPIA  |  DISEASES
56244  |  BTNL2  |  DISEASES
4345  |  CD200  |  DISEASES
7019  |  TFAM  |  DISEASES
6949  |  TCOF1  |  DISEASES
2638  |  GC  |  DISEASES
81792  |  ADAMTS12  |  DISEASES
51428  |  DDX41  |  DISEASES
134430  |  WDR36  |  DISEASES
100289462  |  DEFB4B  |  DISEASES
2920  |  CXCL2  |  DISEASES
1050  |  CEBPA  |  DISEASES
253970  |  SFTA3  |  DISEASES
284  |  ANGPT1  |  DISEASES
4067  |  LYN  |  DISEASES
3066  |  HDAC2  |  DISEASES
3551  |  IKBKB  |  DISEASES
4914  |  NTRK1  |  DISEASES
7178  |  TPT1  |  DISEASES
56413  |  LTB4R2  |  DISEASES
8111  |  GPR68  |  DISEASES
4586  |  MUC5AC  |  DISEASES
26298  |  EHF  |  DISEASES
727897  |  MUC5B  |  DISEASES
5977  |  DPF2  |  DISEASES
930  |  CD19  |  DISEASES
55733  |  HHAT  |  DISEASES
83695  |  RHNO1  |  DISEASES
1232  |  CCR3  |  DISEASES
3684  |  ITGAM  |  DISEASES
50840  |  TAS2R14  |  DISEASES
5027  |  P2RX7  |  DISEASES
57552  |  NCEH1  |  DISEASES
5125  |  PCSK5  |  DISEASES
11153  |  FICD  |  DISEASES
7421  |  VDR  |  DISEASES
8972  |  MGAM  |  DISEASES
28977  |  MRPL42  |  DISEASES
440400  |  RNASEK  |  DISEASES
387521  |  TMEM189  |  DISEASES
5228  |  PGF  |  DISEASES
319089  |  TTC6  |  DISEASES
4065  |  LY75  |  DISEASES
567  |  B2M  |  DISEASES
101  |  ADAM8  |  DISEASES
3949  |  LDLR  |  DISEASES
8778  |  SIGLEC5  |  DISEASES
100507679  |  MUC22  |  DISEASES
64506  |  CPEB1  |  DISEASES
820  |  CAMP  |  DISEASES
115727  |  RASGRP4  |  DISEASES
9294  |  S1PR2  |  DISEASES
2323  |  FLT3LG  |  DISEASES
8740  |  TNFSF14  |  DISEASES
100129528  |  MUC8  |  DISEASES
104355217  |  ERICD  |  DISEASES
102191832  |  FBXW7-AS1  |  DISEASES
100124700  |  HOTAIR  |  DISEASES
100885789  |  IFNG-AS1  |  DISEASES
102723508  |  KANTR  |  DISEASES
103344928  |  KIAA1614-AS1  |  DISEASES
100885779  |  LINC-ROR  |  DISEASES
100302640  |  LINC00882  |  DISEASES
348120  |  LINC01193  |  DISEASES
440823  |  MIAT  |  DISEASES
404744  |  NPSR1-AS1  |  DISEASES
148756  |  OVAAL  |  DISEASES
677800  |  SNORA12  |  DISEASES
26782  |  SNORA66  |  DISEASES
26768  |  SNORA73B  |  DISEASES
9304  |  SNORD22  |  DISEASES
100874231  |  SPATA13-AS1  |  DISEASES
401014  |  TEX41  |  DISEASES
Locus(Waiting for update.)
Disease ID 385
Disease asthma
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:207)
HP:0012384  |  Nasal inflammation  |  171
HP:0003193  |  Allergic rhinitis  |  116
HP:0001513  |  Obesity  |  111
HP:0012393  |  Allergy  |  77
HP:0000716  |  Depression  |  49
HP:0012735  |  Coughing  |  48
HP:0001880  |  Eosinophilia  |  46
HP:0002020  |  Heartburn  |  42
HP:0002099  |  Asthma  |  40
HP:0030828  |  Wheezing  |  36
HP:0100582  |  Nasal polyps  |  34
HP:0011947  |  Respiratory infection  |  29
HP:0000739  |  Anxiety  |  27
HP:0002094  |  Dyspnea  |  26
HP:0012387  |  Bronchitis  |  23
HP:0000964  |  Eczema  |  20
HP:0002090  |  Pneumonia  |  19
HP:0011950  |  Bronchiolitis  |  16
HP:0001047  |  Atopic dermatitis  |  15
HP:0000246  |  Sinus inflammation  |  13
HP:0006510  |  Chronic obstructive pulmonary disease  |  13
HP:0000822  |  Hypertension  |  11
HP:0002633  |  Vasculitis  |  10
HP:0002878  |  Respiratory failure  |  10
HP:0100512  |  Vitamin D deficiency  |  10
HP:0002097  |  Pulmonary emphysema  |  9
HP:0012531  |  Pain  |  8
HP:0001945  |  Fever  |  7
HP:0000708  |  Behavioral problems  |  7
HP:0000819  |  Diabetes mellitus  |  7
HP:0001824  |  Weight loss  |  7
HP:0006528  |  Chronic lung disease  |  6
HP:0002110  |  Bronchiectasis  |  6
HP:0005952  |  Decreased lung function  |  6
HP:0000509  |  Conjunctivitis  |  6
HP:0002098  |  Respiratory distress  |  6
HP:0004469  |  Chronic bronchitis  |  5
HP:0002719  |  infections, recurrent  |  5
HP:0001518  |  Small for gestational age  |  5
HP:0002664  |  Neoplasia  |  5
HP:0002315  |  Headaches  |  4
HP:0006536  |  Obstructive lung disease  |  4
HP:0001941  |  acidemia  |  4
HP:0005943  |  Respiratory arrest  |  4
HP:0002104  |  Absence of spontaneous respiration  |  4
HP:0000855  |  Insulin resistance  |  4
HP:0001631  |  Atria septal defect  |  4
HP:0001695  |  Cardiac arrest  |  3
HP:0011109  |  Chronic sinusitis  |  3
HP:0000670  |  Dental caries  |  3
HP:0002360  |  Sleep disturbance  |  3
HP:0002788  |  Recurrent upper respiratory infection  |  3
HP:0002257  |  Chronic rhinitis  |  3
HP:0002875  |  Exertional dyspnea  |  3
HP:0100543  |  Cognitive deficits  |  3
HP:0012743  |  Central obesity  |  3
HP:0010535  |  Sleep apnea  |  3
HP:0004398  |  Peptic ulcer  |  3
HP:0000939  |  Osteoporosis  |  3
HP:0100633  |  Inflammation of the esophagus  |  3
HP:0001903  |  Anemia  |  3
HP:0012418  |  Low blood oxygen level  |  3
HP:0004313  |  Decreased immunoglobulin level  |  3
HP:0000752  |  Hyperactive behavior  |  3
HP:0002870  |  Obstructive sleep apnea  |  3
HP:0100753  |  Schizophrenia  |  3
HP:0012653  |  Acute severe asthma  |  3
HP:0002076  |  Migraine headaches  |  2
HP:0006532  |  Pneumonia, recurrent episodes  |  2
HP:0001369  |  Arthritis  |  2
HP:0003128  |  Lactic acidosis  |  2
HP:0002791  |  Under breathing  |  2
HP:0002583  |  Colitis  |  2
HP:0002917  |  Low blood magnesium levels  |  2
HP:0002960  |  Autoimmune condition  |  2
HP:0007879  |  Allergic conjunctivitis  |  2
HP:0003212  |  Elevated serum IgE  |  2
HP:0001658  |  Myocardial infarction  |  2
HP:0002883  |  Rapid breathing  |  2
HP:0012115  |  Liver inflammation  |  2
HP:0000388  |  Otitis media  |  2
HP:0003002  |  Breast carcinoma  |  2
HP:0009830  |  Peripheral neuritis  |  2
HP:0005972  |  Respiratory acidosis  |  2
HP:0002113  |  Pulmonary infiltrates  |  2
HP:0100279  |  Ulcerative colitis  |  2
HP:0012378  |  Fatigue  |  2
HP:0011675  |  Arrhythmias  |  2
HP:0001061  |  Acne  |  2
HP:0001742  |  Obstruction of nose  |  2
HP:0002725  |  Systemic lupus erythematosus  |  2
HP:0003765  |  Psoriasis  |  2
HP:0002204  |  Pulmonary embolism  |  2
HP:0000969  |  Dropsy  |  2
HP:0000717  |  Autism  |  2
HP:0100845  |  Anaphylactic shock  |  2
HP:0001025  |  Hives  |  2
HP:0002748  |  Rickets  |  2
HP:0001370  |  Rheumatoid arthritis  |  2
HP:0001618  |  Dysphonia  |  2
HP:0002107  |  Collapsed lung  |  2
HP:0012125  |  Prostate cancer  |  2
HP:0001622  |  Premature delivery  |  1
HP:0011944  |  Small vessel vasculitis  |  1
HP:0100598  |  Pulmonary oedema  |  1
HP:0001638  |  Cardiomyopathy  |  1
HP:0009831  |  Single damaged nerve  |  1
HP:0000010  |  Frequent urinary tract infections  |  1
HP:0001399  |  Liver failure  |  1
HP:0002625  |  Blood clot in a deep vein  |  1
HP:0030833  |  Neck pain  |  1
HP:0001271  |  Polyneuropathy  |  1
HP:0012532  |  Chronic pain  |  1
HP:0005202  |  Helicobacter pylori infection  |  1
HP:0002955  |  Granulomatosis  |  1
HP:0003287  |  Abnormality of mitochondrial metabolism  |  1
HP:0002637  |  Brain ischemia  |  1
HP:0003712  |  Hypertrophic muscles  |  1
HP:0011782  |  Thyroid crisis  |  1
HP:0000394  |  Lop ear  |  1
HP:0200123  |  Chronic liver inflammation  |  1
HP:0011458  |  Abdominal symptom  |  1
HP:0100327  |  Cow milk allergy  |  1
HP:0003477  |  Peripheral axonal neuropathy  |  1
HP:0003613  |  Antiphospholipid antibodies  |  1
HP:0006543  |  Cardiorespiratory arrest  |  1
HP:0000846  |  Hypoadrenalism  |  1
HP:0003763  |  Bruxism  |  1
HP:0004953  |  Abdominal aortic aneurysm  |  1
HP:0002621  |  Atherosclerosis  |  1
HP:0000805  |  Enuresis  |  1
HP:0002880  |  Respiratory difficulties  |  1
HP:0030127  |  Endometriosis  |  1
HP:0000726  |  Dementia  |  1
HP:0100570  |  Carcinoid tumor  |  1
HP:0010783  |  Erythema  |  1
HP:0012193  |  Anaplastic large-cell lymphoma  |  1
HP:0000458  |  Anosmia  |  1
HP:0000651  |  Diplopia  |  1
HP:0001254  |  Lethargy  |  1
HP:0009803  |  Hypoplastic/small phalanges of the hand  |  1
HP:0001978  |  Extramedullary hematopoiesis  |  1
HP:0009733  |  Glioma  |  1
HP:0004417  |  Intermittent claudication  |  1
HP:0100785  |  Insomnia  |  1
HP:0002373  |  Febrile convulsions  |  1
HP:0001678  |  Atrioventricular block  |  1
HP:0002027  |  Abdominal pain  |  1
HP:0002138  |  Subarachnoid hemorrhage  |  1
HP:0007018  |  Attention deficits  |  1
HP:0001510  |  Growth deficiency  |  1
HP:0009381  |  Hypoplastic fingers  |  1
HP:0000988  |  Exanthem  |  1
HP:0040189  |  Desquamation  |  1
HP:0002958  |  Immune dysregulation  |  1
HP:0000099  |  Glomerular nephritis  |  1
HP:0100601  |  Eclampsia  |  1
HP:0001609  |  Hoarseness  |  1
HP:0000750  |  Late-onset speech development  |  1
HP:0001649  |  Tachycardia  |  1
HP:0012219  |  Erythema nodosum  |  1
HP:0001657  |  Prolonged QT interval  |  1
HP:0000217  |  Dry mouth syndrome  |  1
HP:0002527  |  Falls  |  1
HP:0009800  |  gestational diabetes  |  1
HP:0000836  |  Overactive thyroid  |  1
HP:0002665  |  Lymphoma  |  1
HP:0002780  |  Bronchomalacia  |  1
HP:0002863  |  Myelodysplastic syndrome  |  1
HP:0100537  |  Inflammation of the fascia  |  1
HP:0001297  |  Cerebral vascular events  |  1
HP:0010775  |  Vascular ring  |  1
HP:0001648  |  Cor pulmonale  |  1
HP:0002837  |  Recurrent bronchitis  |  1
HP:0040183  |  Encopresis  |  1
HP:0012388  |  Acute bronchitis  |  1
HP:0002091  |  Restrictive ventilatory defect  |  1
HP:0012189  |  Hodgkin disease  |  1
HP:0100699  |  Scarring  |  1
HP:0000501  |  Glaucoma  |  1
HP:0010307  |  Stridor  |  1
HP:0002588  |  Duodenal ulcer  |  1
HP:0000842  |  Elevated insulin level  |  1
HP:0100602  |  Pre-eclampsia  |  1
HP:0040187  |  Neonatal sepsis  |  1
HP:0002015  |  Swallowing difficulty  |  1
HP:0005268  |  Spontaneous abortion  |  1
HP:0002092  |  Pulmonary artery hypertension  |  1
HP:0001262  |  Somnolence  |  1
HP:0000518  |  Cataract  |  1
HP:0002894  |  Neoplasia of the pancreas  |  1
HP:0001635  |  Congestive heart failure  |  1
HP:0100806  |  Sepsis  |  1
HP:0008653  |  Crescentic glomerulonephritis  |  1
HP:0011590  |  Double aortic arch  |  1
HP:0000958  |  Xerosis  |  1
HP:0011108  |  Sinusitis, recurrent  |  1
HP:0001627  |  Congenital heart defects  |  1
HP:0004900  |  Severe lactic acidosis  |  1
HP:0012467  |  Acute respiratory acidosis  |  1
HP:0000952  |  Yellow skin  |  1
HP:0002721  |  Immunodeficiency  |  1
HP:0006579  |  Neonatal jaundice  |  1
HP:0002835  |  Aspiration  |  1
HP:0003473  |  Fatigable weakness  |  1
HP:0001276  |  Hypertonia  |  1
HP:0012819  |  Myocarditis  |  1
Disease ID 385
Disease asthma
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:126)
C0035455  |  rhinitis  |  148
C0028754  |  obesity  |  104
C2607914  |  allergic rhinitis  |  99
C0009450  |  infection  |  76
C0021311  |  infections  |  68
C0002111  |  allergy  |  62
C0011570  |  depression  |  43
C0010200  |  cough  |  38
C0014457  |  eosinophilia  |  35
C0043144  |  wheezing  |  34
C0037090  |  respiratory symptoms  |  30
C0001883  |  airway obstruction  |  26
C0043144  |  wheeze  |  26
C0013404  |  dyspnea  |  24
C0003467  |  anxiety  |  23
C0149516  |  chronic rhinosinusitis  |  17
C0032285  |  pneumonia  |  17
C0006271  |  bronchiolitis  |  16
C0699949  |  airway disease  |  15
C0011615  |  atopic dermatitis  |  14
C0004031  |  allergic bronchopulmonary aspergillosis  |  13
C0035473  |  rhinovirus  |  13
C0006266  |  bronchospasm  |  13
C0042769  |  viral infection  |  12
C0021400  |  influenza  |  12
C0010201  |  chronic cough  |  12
C0042769  |  virus infection  |  12
C0037199  |  sinusitis  |  11
C0035243  |  respiratory infections  |  11
C0020538  |  hypertension  |  10
C0024115  |  lung disease  |  10
C0011603  |  dermatitis  |  10
C0042384  |  vasculitis  |  10
C0017168  |  gastroesophageal reflux  |  9
C0035243  |  respiratory infection  |  9
C0334108  |  polyposis  |  9
C0016470  |  food allergy  |  9
C0013990  |  emphysema  |  8
C0030193  |  pain  |  8
C0085129  |  bronchial hyperresponsiveness  |  8
C0231303  |  distress  |  8
C0032285  |  pneumoniae  |  7
C1145670  |  respiratory failure  |  7
C0032285  |  lung inflammation  |  7
C0006267  |  bronchiectasis  |  6
C0001883  |  airways obstruction  |  6
C0010200  |  coughing  |  6
C0035243  |  respiratory tract infections  |  6
C0276447  |  rhinovirus infection  |  6
C0042769  |  viral infections  |  5
C0242379  |  lung cancer  |  5
C0410000  |  overlap syndrome  |  5
C0032285  |  pulmonary inflammation  |  5
C0856169  |  endothelial dysfunction  |  4
C0699949  |  airways disease  |  4
C0004623  |  bacterial infections  |  4
C0013404  |  breathlessness  |  4
C0422833  |  ent symptoms  |  4
C0008677  |  chronic bronchitis  |  4
C0008728  |  churg-strauss syndrome  |  3
C0476273  |  respiratory distress  |  3
C0029456  |  osteoporosis  |  3
C0948780  |  rhinosinusitis  |  3
C0008711  |  chronic rhinitis  |  3
C0085129  |  bronchial hyperreactivity  |  3
C0231818  |  airway constriction  |  3
C0426576  |  gastrointestinal symptoms  |  3
C0009443  |  common cold  |  3
C1393529  |  vascular complications  |  3
C0017168  |  gastroesophageal reflux disease  |  3
C0037090  |  pulmonary symptoms  |  3
C0262471  |  ent problem  |  2
C0011849  |  diabetes mellitus  |  2
C0022104  |  irritable bowel syndrome  |  2
C0024117  |  chronic obstructive pulmonary disease (copd)  |  2
C0347950  |  asthmatic attack  |  2
C0231912  |  nocturnal cough  |  2
C0851578  |  sleep disorders  |  2
C0041296  |  tuberculosis  |  2
C0001125  |  lactic acidosis  |  2
C0232292  |  chest tightness  |  2
C0018621  |  pollen allergy  |  2
C0017168  |  acid reflux  |  2
C1841971  |  glucocorticoid resistance  |  2
C0027051  |  myocardial infarction  |  2
C0034068  |  pulmonary eosinophilia  |  2
C0004364  |  autoimmune diseases  |  2
C0151723  |  hypomagnesemia  |  2
C0149931  |  migraine  |  2
C0026896  |  myasthenia gravis  |  1
C0917801  |  insomnia  |  1
C0020550  |  hyperthyroidism  |  1
C0851901  |  rhinoviral infections  |  1
C0334421  |  glomangioma  |  1
C0041912  |  upper respiratory infections  |  1
C0024117  |  chronic airway disease  |  1
C0015263  |  exercise-induced bronchospasm  |  1
C1527344  |  dysphonia  |  1
C0085605  |  liver failure  |  1
C0003469  |  anxiety disorders  |  1
C0694549  |  community-acquired pneumonia  |  1
C0015967  |  fever  |  1
C0744318  |  gastroesophageal reflux symptoms  |  1
C0085129  |  bronchial hypersensitivity  |  1
C0004059  |  aspirin intolerance  |  1
C0264490  |  acute respiratory failure  |  1
C0006266  |  bronchospasms  |  1
C0233401  |  psychiatric symptoms  |  1
C0162539  |  igg subclass deficiency  |  1
C0031117  |  peripheral neuropathy  |  1
C0235162  |  sleep difficulties  |  1
C0032302  |  mycoplasma pneumonia  |  1
C0029896  |  ent diseases  |  1
C0264558  |  tension pneumothorax  |  1
C0013404  |  dyspnoea  |  1
C0863094  |  recurrent respiratory tract infections  |  1
C0004096  |  airway hyperreactivity  |  1
C0037317  |  sleep disturbances  |  1
C1698398  |  eosinophilic bronchitis  |  1
C0034072  |  cor pulmonale  |  1
C0017168  |  gastro-oesophageal reflux  |  1
C0015672  |  fatigue  |  1
C0231819  |  air trapping  |  1
C0033774  |  itching  |  1
C1839611  |  n syndrome  |  1
C0036202  |  sarcoidosis  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:602)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs10036748226949307124TNFumls:C0004096BeFreeMultiple single nucleotide polymorphisms in the TNFAIP3 interacting protein 1 (TNIP1) gene, which interacts with TNFAIP3 and inhibits the TNF-α-induced nuclear factor κB inflammation pathway, were associated with asthma: rs1422673 (P = 3.44 × 10(-7)) and rs10036748 (P = 1.41 × 10(-6), r(2) = 0.67).0.2658279742012TNIP15151078585CT
rs10036748226949307128TNFAIP3umls:C0004096BeFreeMultiple single nucleotide polymorphisms in the TNFAIP3 interacting protein 1 (TNIP1) gene, which interacts with TNFAIP3 and inhibits the TNF-α-induced nuclear factor κB inflammation pathway, were associated with asthma: rs1422673 (P = 3.44 × 10(-7)) and rs10036748 (P = 1.41 × 10(-6), r(2) = 0.67).0.0005428842012TNIP15151078585CT
rs10036748NA10318TNIP1umls:C0004096GADNA0.002638474NATNIP15151078585CT
rs100367482269493010318TNIP1umls:C0004096BeFreeThe T allele of rs10036748 in the TNIP1 gene is the minor protective allele for asthma but the minor or major risk allele for systemic lupus erythematosus and systemic sclerosis in non-Hispanic white or Chinese subjects, respectively.0.0026384742012TNIP15151078585CT
rs100442542448606923194FBXL7umls:C0004096GWASCATHowever, these 3 SNPs were not additionally replicated in the adult asthmatic patients of the remaining trials. rs10044254 lies in the intronic region of F-box and leucine-rich repeat protein 7 (FBXL7) and is associated with decreased expression in immortalized B cells derived from CAMP participants.0.122013FBXL7515783487AG
rs1007591411022011114899C1QTNF3umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA534525826AG
rs1008723NA55876GSDMBumls:C0004096GADNA0.263279326NAGSDMB1739910014GT
rs101230724824216101929231LOC101929231umls:C0004096GWASCATGenome-wide interaction studies reveal sex-specific asthma risk alleles.0.122015LOC1019292312149798707AC
rs1018765422424883151507MSL3P1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012NA2233905414CT
rs10197862243880139173IL1RL1umls:C0004096GWASCATGenome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.0.2670894442013IL1RL12102350089AG
rs1022400NA3459IFNGR1umls:C0004096GADNA0.009468128NANA6137352903TC
rs10399931194214041116CHI3L1umls:C0004096BeFreeInterestingly, it has been reported that rs10399931 (-329 G/A) of CHI3LI contributes to the inter-individual plasma YKL-40 levels in patients with sarcoidosis, and that rs4950928 (-131 C/G) is a susceptibility polymorphism for asthma and a decline in lung function.0.016806992009CHI3L11203186952TC
rs104271322328447154ADRB2umls:C0004096BeFreeThese results suggest that in the group of mestizo schoolchildren studied, the Arg16Gly and Gln27Glu polymorphisms are not markers of susceptibility or severity of asthma and do not affect ADRB2 gene expression during the rescue therapy.0.2687741092012ADRB25148826877GA
rs104271321829036154ADRB2umls:C0004096BeFreeWe were the first to analyze Arg16Gly ADRB2 gene polymorphism in Japanese patients with AERD, and showed that Arg16Gly ADRB2 gene polymorphism in Japanese patients with AERD is different from that in the patients with ATA.0.2687741092011ADRB25148826877GA
rs104271326505596154ADRB2umls:C0004096BeFreeTo compare the effectiveness and safety of tiotropium vs LABAs, when used with inhaled corticosteroids (ICS) in black adults with asthma and to determine whether allelic variation at the Arg16Gly locus of the β2-adrenergic receptor (ADRB2) geneis associated with treatment response.0.2687741092015ADRB25148826877GA
rs1042713197451607421VDRumls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.0177171242010ADRB25148826877GA
rs104271319077707154ADRB2umls:C0004096BeFreeEarly studies suggest that bronchodilator reversibility and asthma worsening in patients on continuous short-acting and long-acting beta-agonists are related to the Gly16Arg genotype for the ADRB2.0.2687741092009ADRB25148826877GA
rs104271319183167154ADRB2umls:C0004096BeFreeAdditive role of tiotropium in severe asthmatics and Arg16Gly in ADRB2 as a potential marker to predict response.0.2687741092009ADRB25148826877GA
rs104271324838642931MS4A1umls:C0004096BeFreeThe MS4A2 C-109T T/T and ADRB2 R16G A/A genotypes were associated with asthma in the Chinese Han children.0.0066341572014ADRB25148826877GA
rs1042713248386422206MS4A2umls:C0004096BeFreeThe MS4A2 C-109T T/T and ADRB2 R16G A/A genotypes were associated with asthma in the Chinese Han children.0.0552223852014ADRB25148826877GA
rs1042713113714094760NEUROD1umls:C0004096BeFreeRecent studies have suggested that two polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) gene at codons 16 (arginine to glycine) and 27 (glutamine to glutamate) affect an individual's airway responsiveness, or response to acute or chronic beta(2)-agonist therapy but are not risk factors for asthma.0.0135720942001ADRB25148826877GA
rs10427131137140910383TUBB4Bumls:C0004096BeFreeRecent studies have suggested that two polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) gene at codons 16 (arginine to glycine) and 27 (glutamine to glutamate) affect an individual's airway responsiveness, or response to acute or chronic beta(2)-agonist therapy but are not risk factors for asthma.0.0135720942001ADRB25148826877GA
rs104271324838642154ADRB2umls:C0004096BeFreeThe MS4A2 C-109T T/T and ADRB2 R16G A/A genotypes were associated with asthma in the Chinese Han children.0.2687741092014ADRB25148826877GA
rs1042713197451607040TGFB1umls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.2907425092010ADRB25148826877GA
rs104271322075484154ADRB2umls:C0004096BeFreeWe tested the hypothesis that three functional polymorphisms in the ADRB2 gene (Thr164Ile, Gly16Arg and Gln27Glu) are associated with reduced lung function, asthma or chronic obstructive pulmonary disease (COPD).0.2687741092012ADRB25148826877GA
rs104271318849614154ADRB2umls:C0004096BeFreeThe authors analyze the possible implication of 7 genetic polymorphisms described as asthma susceptibility genes: IL13 (C-1112T and R130Q), IL4RA (I50V, Q551R), IL5 (C-746T) and ADRB2 (Q27E and R16G) in specific olive pollen allergic sensitization.0.2687741092009ADRB25148826877GA
rs1042713188496143567IL5umls:C0004096BeFreeThe authors analyze the possible implication of 7 genetic polymorphisms described as asthma susceptibility genes: IL13 (C-1112T and R130Q), IL4RA (I50V, Q551R), IL5 (C-746T) and ADRB2 (Q27E and R16G) in specific olive pollen allergic sensitization.0.2454141262009ADRB25148826877GA
rs104271319745160154ADRB2umls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.2687741092010ADRB25148826877GA
rs104271422075484154ADRB2umls:C0004096BeFreeWe tested the hypothesis that three functional polymorphisms in the ADRB2 gene (Thr164Ile, Gly16Arg and Gln27Glu) are associated with reduced lung function, asthma or chronic obstructive pulmonary disease (COPD).0.2687741092012ADRB25148826910GC,T
rs10427141137140910383TUBB4Bumls:C0004096BeFreeRecent studies have suggested that two polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) gene at codons 16 (arginine to glycine) and 27 (glutamine to glutamate) affect an individual's airway responsiveness, or response to acute or chronic beta(2)-agonist therapy but are not risk factors for asthma.0.0135720942001ADRB25148826910GC,T
rs104271418849614154ADRB2umls:C0004096BeFreeThe authors analyze the possible implication of 7 genetic polymorphisms described as asthma susceptibility genes: IL13 (C-1112T and R130Q), IL4RA (I50V, Q551R), IL5 (C-746T) and ADRB2 (Q27E and R16G) in specific olive pollen allergic sensitization.0.2687741092009ADRB25148826910GC,T
rs1042714188496143567IL5umls:C0004096BeFreeThe authors analyze the possible implication of 7 genetic polymorphisms described as asthma susceptibility genes: IL13 (C-1112T and R130Q), IL4RA (I50V, Q551R), IL5 (C-746T) and ADRB2 (Q27E and R16G) in specific olive pollen allergic sensitization.0.2454141262009ADRB25148826910GC,T
rs104271422328447154ADRB2umls:C0004096BeFreeThese results suggest that in the group of mestizo schoolchildren studied, the Arg16Gly and Gln27Glu polymorphisms are not markers of susceptibility or severity of asthma and do not affect ADRB2 gene expression during the rescue therapy.0.2687741092012ADRB25148826910GC,T
rs1042714113714094760NEUROD1umls:C0004096BeFreeRecent studies have suggested that two polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) gene at codons 16 (arginine to glycine) and 27 (glutamine to glutamate) affect an individual's airway responsiveness, or response to acute or chronic beta(2)-agonist therapy but are not risk factors for asthma.0.0135720942001ADRB25148826910GC,T
rs1047266188296838795TNFRSF10Bumls:C0004096BeFreeIn the initial sample, three SNPs, rs320995 in the cysteinyl leukotriene receptor 1 gene, rs1047266 in the tumour necrosis factor receptor superfamily, member 10b, gene and rs40401 in the interleukin-3 gene, were associated with risk of asthma.0.0002714422009TNFRSF10B823043188GA
rs1047266188296833562IL3umls:C0004096BeFreeIn the initial sample, three SNPs, rs320995 in the cysteinyl leukotriene receptor 1 gene, rs1047266 in the tumour necrosis factor receptor superfamily, member 10b, gene and rs40401 in the interleukin-3 gene, were associated with risk of asthma.0.0103583982009TNFRSF10B823043188GA
rs104893908258157732908NR3C1umls:C0004096BeFreeAssociation of the glucocorticoid receptor D641V variant with steroid-resistant asthma: a case-control study.0.1036789132016NR3C15143295561TA
rs104893909224697832908NR3C1umls:C0004096BeFreeThe N363S and I559N single nucleotide polymorphisms of the h-GR/NR3C1 gene in patients with bronchial asthma.0.1036789132012NR3C15143300556AT
rs1048943222367192950GSTP1umls:C0004096BeFreeTo assess the effect of IL13 (-1112 C>T and Arg110Gln), GSTP1 (Ile105Val), and CYP1A1 (Ile462Val) on asthma risk and ETS exposure, we recruited 201 unrelated children and classified them into four groups: (1) control without ETS exposure; (2) control with ETS exposure; (3) with asthma and with ETS exposure and (4) with asthma and without ETS exposure.0.2239365422012CYP1A11574720644TG,C,A
rs1048943222367193596IL13umls:C0004096BeFreeTo assess the effect of IL13 (-1112 C>T and Arg110Gln), GSTP1 (Ile105Val), and CYP1A1 (Ile462Val) on asthma risk and ETS exposure, we recruited 201 unrelated children and classified them into four groups: (1) control without ETS exposure; (2) control with ETS exposure; (3) with asthma and with ETS exposure and (4) with asthma and without ETS exposure.0.4905192532012CYP1A11574720644TG,C,A
rs1048990253759075687PSMA6umls:C0004096BeFreeHowever, when male and female study subjects were considered separately, we found that the CG genotype of PSMA6 rs1048990 is significantly more frequent in male asthma patients compared to male control subjects.0.0002714422015PSMA61435292469CG,T
rs1048990253759075706PSMC6umls:C0004096BeFreeTo investigate polymorphisms of proteasomal genes PSMA6 (rs1048990 and rs2277460), PSMC6 (rs2295826 and rs2295827) and PSMA3 (rs2348071) in Lithuanian patients with asthma.0.0002714422015PSMA61435292469CG,T
rs104951791102201111221DUSP10umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1221796026CT
rs1050501245865892213FCGR2Bumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0002714422014FCGR2B1161674008TC
rs1050501245865892214FCGR3Aumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0031813582014FCGR2B1161674008TC
rs1050501245865892212FCGR2Aumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0029957922014FCGR2B1161674008TC
rs1051292811022011108ADCY2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.1223670322000ADCY257546298CT
rs105158071991002857628DPP10umls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.1116616862010ADRA1B;LOC1019277905159937991GA
rs10515807199100285621PRNPumls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.0050055062010ADRA1B;LOC1019277905159937991GA
rs1051580719910028147ADRA1Bumls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.0050055062010ADRA1B;LOC1019277905159937991GA
rs105168092242488351191HERC5umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012HERC5488499935AG
rs1056836195750275444PON1umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0029099162009CYP1B1238071060GC
rs1056836195750271545CYP1B1umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0026384742009CYP1B1238071060GC
rs10568361957502754578UGT1A6umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0026384742009CYP1B1238071060GC
rs1063355201592423119HLA-DQB1umls:C0004096BeFreeThe HLA-DR/DQ region on chromosome 6p21.3 was also associated with asthma: rs1063355 in the 3' untranslated region of HLA-DQB1 (P = 9.55E-06).0.1659497542010HLA-DQB1;HLA-DQB1-AS1632659937TG
rs10720381102201157703CWC22umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA2180485103AG
rs10759931242437407099TLR4umls:C0004096BeFreeThe TLR4 single-nucleotide polymorphisms rs1927911, rs10759931, and rs6478317 modified the association of particulate matter and nitrogen dioxide with asthma.0.0579989362014NA9117701869GA
rs107620581918733229119CTNNA3umls:C0004096GAD[Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis.]0.1234527992009CTNNA31066328750CG
rs1076619721613960120227CYP2R1umls:C0004096BeFreeOnly the CYP2R1 SNP rs10766197 homozygous minor genotype was associated with asthma (P = 0.044).0.0052769482011NA1114900334GA
rs10781329110220118395PIP5K1Bumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0026384742000PIP5K1B969003329GA
rs10789166218273233716JAK1umls:C0004096BeFreeJAK-1 rs2780895 C-related genotype and allele but not JAK-1 rs10789166, rs4916008, rs2780885, rs17127114, and rs3806277 are associated with higher susceptibility to asthma.0.0026384742011JAK1164847130AG
rs10800812110220111999ELF3umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1202086810AG
rs108082652242488391584PLXNA4umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012PLXNA47132504930GA
rs10830196217344005791PTPREumls:C0004096BeFreeRAD50 (rs2706347) and PTPRE (rs10830196) revealed crude associations with asthma at a Bonferroni-corrected level of significance (p < 0.0011).0.0029099162011PTPRE10127925448CT
rs10875595224248836879TAF7umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012TAF75141320922TG
rs1088628911022011143384CACUL1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000CACUL110118704208GT
rs108907841102201154734RAB39Aumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000RAB39A11107954513GA
rs10912477NA356FASLGumls:C0004096GADNA0.002638474NANA1172826855AC
rs10917661245865892213FCGR2Bumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0002714422014FCGR2B1161671427CT
rs10917661245865892214FCGR3Aumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0031813582014FCGR2B1161671427CT
rs10917661245865892212FCGR2Aumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0029957922014FCGR2B1161671427CT
rs109249931839555056605ERO1LBumls:C0004096BeFreePolymorphisms at the loci of nearby genes for NRG1 (rs4512342) and ERO1LB (rs10924993) were associated with neither the occurrence of nor exacerbations of asthma.0.0026384742008NA1236296485TG
rs10924993183955503084NRG1umls:C0004096BeFreePolymorphisms at the loci of nearby genes for NRG1 (rs4512342) and ERO1LB (rs10924993) were associated with neither the occurrence of nor exacerbations of asthma.0.0026384742008NA1236296485TG
rs10984561224248831620BRINP1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012LOC1053762509119496299CT
rs11000019238296865660PSAPumls:C0004096GWASCATRank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.0.122013PSAP1071831773GA
rs110199921804549149628PYHIN1umls:C0004096GWASCATIn addition, we identified a new asthma susceptibility locus at PYHIN1, with the association being specific to individuals of African descent (P = 3.9 × 10(-9)).0.2431813582011PYHIN11158962765CT
rs110199921804549149628PYHIN1umls:C0004096GAD[In addition, we identified a new asthma susceptibility locus at PYHIN1, with the association being specific to individuals of African descent (P = 3.9 A 10(-9)).]0.2431813582011PYHIN11158962765CT
rs110374661102201155761TTC17umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1143532377AG
rs11064153110220116337SCNN1Aumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000LTBR;SCNN1A126379284TC
rs11071559208605036095RORAumls:C0004096GWASCATA large-scale, consortium-based genomewide association study of asthma.0.1202714422010RORA1560777789CT
rs110789272180454955876GSDMBumls:C0004096GWASCATMeta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.0.2632793262011GSDMB1739908152CT
rs110789272180454955876GSDMBumls:C0004096GAD[Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.]0.2632793262011GSDMB1739908152CT
rs111188641102201111221DUSP10umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1221806025CT
rs11214966218045494837NNMTumls:C0004096GAD[Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.]0.0023670322011LOC10192894011114360533TC
rs1121496621804549101928940LOC101928940umls:C0004096GWASCATMeta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.0.122011LOC10192894011114360533TC
rs1131882235170376625SNRNP70umls:C0004096BeFreeWe performed comprehensive sequencing of the TBXA2R gene in 48 Japanese control subjects and found a set of variants (SNP1 G>T rs2238634, SNP2 T>G rs2238633, SNP3 C>T rs2238632 and SNP4 G>A rs2238631) in intron 1 in linkage disequilibrium with c.795 T>C rs1131882, which was previously reported to be associated with asthma and related phenotypes.0.0005428842013TBXA2R193595925GA
rs113641019484672142PARP1umls:C0004096BeFreeThe Ala allele at Val762Ala polymorphism in poly(ADP-ribose) polymerase-1 (PARP-1) gene is associated with a decreased risk of asthma in a Turkish population.0.1237242412009PARP11226367601AG
rs1138272244650307124TNFumls:C0004096BeFreeGSTP1 rs1138272 and TNF rs1800629 SNPs were associated with asthma and wheeze, respectively.0.2658279742014GSTP11167586108CT
rs1138272244650302950GSTP1umls:C0004096BeFreeChildren carrying GSTP1 rs1138272 or rs1695 minor alleles may constitute a susceptible population at increased risk of asthma associated with air pollution.0.2239365422014GSTP11167586108CT
rs114666512081531210333TLR6umls:C0004096BeFreeFurthermore, a positive association was observed between the T allele of rs2381289 in TLR6 and allergic rhinitis in asthma (OR, 1.79; 95% CI, 1.10-2.91; P = .025), while the A allele of rs11466651 in TLRIO was negatively associated with allergic rhinitis (OR, 0.49; 95% CI, 0.26-0.95; P = .046).0.020736662010TLR10438774699CT
rs114818622424883143098MPP7umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012LOC1053764671028328706CG
rs11676357192649733631INPP4Aumls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.0077298562009INPP4A298491814AG
rs1168613522424883728597DCDC2Cumls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012NA24271386TC
rs11718105192649734638MYLKumls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.0173598052009MYLK3123744861CT
rs117792542487617364478CSMD1umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0026384742015CSMD184391552GC
rs11779254248761738477GPR65umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0002714422015CSMD184391552GC
rs11779254248761736660SOX5umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0002714422015CSMD184391552GC
rs11810332NA356FASLGumls:C0004096GADNA0.002638474NANA1172820625AG
rs120521790705140913PPIAP10umls:C0004096BeFreeCRP single nucleotide polymorphisms (SNPs) did not increase the risk of asthma, but CRP rs1205 CC genotype significantly decreased the predictive value of forced vital capacity (FVC) in the asthma group (adjusted mean change = -7.54%, 95% CI = -13.82 to -1.25%).0.0005428842011CRP1159712443CT
rs1212171224687304804NGFRumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0026384742012NTRK2984667612CT
rs1212171224687302534FYNumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0056342662012NTRK2984667612CT
rs121908755225337791080CFTRumls:C0004096BeFreeTo find out the association of S549N and IVS8-5T variants of the CFTR gene with bronchial asthma and its severity and to assess the combinational effect of S549N and IVS8-5T variants on severity of disease.0.0256463582012CFTR7117587800GA,T
rs122127402249847654738FEVumls:C0004096BeFreeWe found variant rs12212740, an intronic SNP of ATG5, to be associated with asthma and forced expiratory volume in 1 second (FEV(1)) percent predicted in the French Canadian population and with FEV(1) in an American Caucasian cohort.0.0211724662012ATG56106301433GA
rs1229540NA6863TAC1umls:C0004096GADNA0.014992773NANA797794082GA
rs12351127110220119568GABBR2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000GABBR2998533135CT
rs12361312192649732206MS4A2umls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.0552223852009NA1160085123CT
rs1237137311022011121256TMEM132Dumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000TMEM132D12129226901GA
rs124503232438801322806IKZF3umls:C0004096GWASCATGenome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.0.1210857672013IKZF31739816455GT
rs125701882382968660495HPSE2umls:C0004096GWASCATRank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.0.122013HPSE21099095945CT
rs1261572122424883347730LRRTM1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012LOC102724542281629402GA
rs12712969224248835581PRKCEumls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012PRKCE246105030CT
rs12941150224248836662SOX9umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012NA1772367254GA
rs1295686208605033596IL13umls:C0004096GWASCATA large-scale, consortium-based genomewide association study of asthma.0.4905192532010IL135132660151TC
rs1295686208605033596IL13umls:C0004096GAD[Asthma is genetically heterogeneous. A few common alleles are associated with disease risk at all ages. Implicated genes suggest a role for communication of epithelial damage to the adaptive immune system and activation of airway inflammation. Variants at]0.4905192532010IL135132660151TC
rs13361200110220111794DOCK2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000DOCK25170054488TC
rs13408661230284838809IL18R1umls:C0004096BeFreeWe also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus.0.1426367532012IL1RL12102338622GA
rs13408661230284839173IL1RL1umls:C0004096BeFreeWe also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus.0.2670894442012IL1RL12102338622GA
rs13408661230284839173IL1RL1umls:C0004096GWASCATWe also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus.0.2670894442012IL1RL12102338622GA
rs13423262086050326953RANBP6umls:C0004096GAD[Asthma is genetically heterogeneous. A few common alleles are associated with disease risk at all ages. Implicated genes suggest a role for communication of epithelial damage to the adaptive immune system and activation of airway inflammation. Variants at]0.0047340642010NA96190076AC
rs1422673NA10318TNIP1umls:C0004096GADNA0.002638474NATNIP15151059427CT
rs1422673226949307124TNFumls:C0004096BeFreeMultiple single nucleotide polymorphisms in the TNFAIP3 interacting protein 1 (TNIP1) gene, which interacts with TNFAIP3 and inhibits the TNF-α-induced nuclear factor κB inflammation pathway, were associated with asthma: rs1422673 (P = 3.44 × 10(-7)) and rs10036748 (P = 1.41 × 10(-6), r(2) = 0.67).0.2658279742012TNIP15151059427CT
rs1422673226949307128TNFAIP3umls:C0004096BeFreeMultiple single nucleotide polymorphisms in the TNFAIP3 interacting protein 1 (TNIP1) gene, which interacts with TNFAIP3 and inhibits the TNF-α-induced nuclear factor κB inflammation pathway, were associated with asthma: rs1422673 (P = 3.44 × 10(-7)) and rs10036748 (P = 1.41 × 10(-6), r(2) = 0.67).0.0005428842012TNIP15151059427CT
rs14358791991002857628DPP10umls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.1116616862010DPP102114735310AG
rs1435879199100285621PRNPumls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.0050055062010DPP102114735310AG
rs143587919910028147ADRA1Bumls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.0050055062010DPP102114735310AG
rs1441585223760402206MS4A2umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0552223852012MS4A21160088238TC
rs1441585223760401493CTLA4umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0381961542012MS4A21160088238TC
rs1441585223760407124TNFumls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.2658279742012MS4A21160088238TC
rs1441586213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011MS4A21160088555TC
rs1441586213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011MS4A21160088555TC
rs14535592262659222806IKZF3umls:C0004096BeFreeSixteen SNPs were significantly associated with asthma after multiple testing correction (P ≤ .01), of which 5 (rs2290400, rs8079416, rs3894194, rs7212938, and rs3859192) were strongly associated (FDR P ≤ .0002), and one was novel (IKZF3-rs1453559).0.1210857672012IKZF31739864166TC
rs1538246NA2625GATA3umls:C0004096GADNA0.094625523NANA108325907AC
rs1588265194269555144PDE4Dumls:C0004096GWASCATGenome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.0.2466341572009PDE4D560073967AG
rs1588265194269555144PDE4Dumls:C0004096GAD[Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.]0.2466341572009PDE4D560073967AG
rs1682273211022011255104TMCO4umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000TMCO4119688807GA
rs16848610110220117135TNNI1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1201454530AC
rs1685102011022011134ADORA1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0058198312000ADORA11203164524GT
rs168561862242488385414SLC45A3umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012NA1205708998TG
rs16925863NA5789PTPRDumls:C0004096GADNA0.009825446NAPTPRD910354770TC
rs1692911102201110370CITED2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA6140139871GC
rs169378831918733225769SLC24A2umls:C0004096GAD[These findings suggested that multiple genetic polymorphisms of CTNNA3 may be determinants of susceptibility to TDI-induced asthma.]0.0023670322009NA920098713AG
rs1695244650302950GSTP1umls:C0004096BeFreeChildren carrying GSTP1 rs1138272 or rs1695 minor alleles may constitute a susceptible population at increased risk of asthma associated with air pollution.0.2239365422014GSTP11167585218AG
rs1695162957822950GSTP1umls:C0004096BeFreeGSTP1 Ile105Val polymorphism was determined using a single based extension method in 88 AIA subjects and compared to 154 aspirin-tolerant asthma (ATA) subjects and 119 normal healthy controls (NC) recruited from the Korean population.0.2239365422005GSTP11167585218AG
rs1695222367192950GSTP1umls:C0004096BeFreeTo assess the effect of IL13 (-1112 C>T and Arg110Gln), GSTP1 (Ile105Val), and CYP1A1 (Ile462Val) on asthma risk and ETS exposure, we recruited 201 unrelated children and classified them into four groups: (1) control without ETS exposure; (2) control with ETS exposure; (3) with asthma and with ETS exposure and (4) with asthma and without ETS exposure.0.2239365422012GSTP11167585218AG
rs1695200322672950GSTP1umls:C0004096BeFreeMeta-analysis of GSTP1 Ile105Val (n = 17) and asthma suggested a possible protective effect of the Val allele, but heterogeneity was extreme.0.2239365422010GSTP11167585218AG
rs1695170881352950GSTP1umls:C0004096BeFreeChildren with asthma with val/val genotype at GSTP1 ile105val locus may be good candidates for supplemental antioxidant therapy.0.2239365422006GSTP11167585218AG
rs1695180570982950GSTP1umls:C0004096BeFreeIf confirmed by independent studies, our results suggest that GSTP1 Ile105Val genotype strongly determines the progression of BHR to physician-diagnosed asthma in the general population.0.2239365422008GSTP11167585218AG
rs1695222367193596IL13umls:C0004096BeFreeTo assess the effect of IL13 (-1112 C>T and Arg110Gln), GSTP1 (Ile105Val), and CYP1A1 (Ile462Val) on asthma risk and ETS exposure, we recruited 201 unrelated children and classified them into four groups: (1) control without ETS exposure; (2) control with ETS exposure; (3) with asthma and with ETS exposure and (4) with asthma and without ETS exposure.0.4905192532012GSTP11167585218AG
rs1695213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011GSTP11167585218AG
rs1695153008482950GSTP1umls:C0004096BeFreeThe polymorphism c.342A>G (p.I105V) in GSTP1 has previously been suggested as a risk factor for asthma.0.2239365422004GSTP11167585218AG
rs1695213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011GSTP11167585218AG
rs16969966192649733690ITGB3umls:C0004096GAD[Of the 160 SNPs previously genotyped in these 39 genes, 10 SNPs in 6 genes were significantly associated with asthma (including the first independent replication for asthma-associated integrin beta(3) ITGB3).]0.0115399742009NA1747241086CA
rs1701704218045486821SUOXumls:C0004096GAD[Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.]0.0023670322011IKZF4;LOC1053697811256018703TG
rs17017042180454864375IKZF4umls:C0004096GWASCATGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.0.122011IKZF4;LOC1053697811256018703TG
rs1703350623829686100130503LOC100130503umls:C0004096GWASCATRank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.0.122013NA335598334GT
rs170645201102201123327NEDD4Lumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0026384742000NEDD4L1858242398CT
rs17084857110220112835GPR12umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0047340642000NA1326895631TC
rs171156741102201184075FSCBumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1444870240TC
rs1712140322424883178AGLumls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012AGL199870421AG
rs17127114218273233716JAK1umls:C0004096BeFreeJAK-1 rs2780895 C-related genotype and allele but not JAK-1 rs10789166, rs4916008, rs2780885, rs17127114, and rs3806277 are associated with higher susceptibility to asthma.0.0026384742011JAK1164870148GA
rs17226566249027624695NDUFA2umls:C0004096BeFreeWe observed two interactions between SNPs in CD14 and LY96 with environmental endotoxin exposure in relation to hospital admissions due to asthma exacerbation which remained significant after correction for multiple testing (CD14 SNPs rs2915863 and LY96 SNP rs17226566).0.0122148842014LY96874007677TC
rs172265662490276223643LY96umls:C0004096BeFreeWe observed two interactions between SNPs in CD14 and LY96 with environmental endotoxin exposure in relation to hospital admissions due to asthma exacerbation which remained significant after correction for multiple testing (CD14 SNPs rs2915863 and LY96 SNP rs17226566).0.0002714422014LY96874007677TC
rs17294280243880134088SMAD3umls:C0004096GWASCATGenome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.0.1229099162013SMAD31567175947AG
rs175254722012508829106SCG3umls:C0004096GAD[Genome-wide association study of recurrent early-onset major depressive disorder.]0.0023670322011NA1551677471TC
rs175254722015924223312DMXL2umls:C0004096GAD[This GWAS confirmed the important role of T(H)2 cytokine and antigen presentation genes in asthma at a genome-wide level and the importance of additional investigation of these 2 regions to delineate their structural complexity and biologic function in th]0.0023670322010NA1551677471TC
rs17593068213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011GSTP11167583461GT
rs17593068213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011GSTP11167583461GT
rs1778983419264973387129NPSR1umls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.1825957542009NPSR1;NPSR1-AS1734831716AG
rs1786929191873323880KRT19umls:C0004096BeFreeA genetic polymorphism in the 3' downstream region of CTNNA3 (rs1786929), as identified by DNA direct sequencing, was significantly associated with the TDI-induced asthma phenotype (P=0.015 in recessive analysis model) and the prevalence of serum-specific IgG to cytokeratin 19 (P=0.031).0.1202714422009CTNNA31065919290AG
rs1799724188116224049LTAumls:C0004096BeFreeThe following study populations were genotyped for 4 polymorphisms within TNF-beta (rs909253) and TNF-alpha (rs1799964, rs1799724, rs1800629): 322 asthmatic children, 151 children with severe respiratory syncytial virus (RSV) bronchiolitis and 270 controls.0.049488432009LTA;TNF631574705CT
rs1799964188116224049LTAumls:C0004096BeFreeThe following study populations were genotyped for 4 polymorphisms within TNF-beta (rs909253) and TNF-alpha (rs1799964, rs1799724, rs1800629): 322 asthmatic children, 151 children with severe respiratory syncytial virus (RSV) bronchiolitis and 270 controls.0.049488432009LTA;TNF;LOC100287329631574531TC
rs1799983229668864846NOS3umls:C0004096BeFreeG894T polymorphism of eNOS gene is a predictor of response to combination of inhaled corticosteroids with long-lasting β2-agonists in asthmatic children.0.0311809352012NOS37150999023TG
rs1800629188116224049LTAumls:C0004096BeFreeThe following study populations were genotyped for 4 polymorphisms within TNF-beta (rs909253) and TNF-alpha (rs1799964, rs1799724, rs1800629): 322 asthmatic children, 151 children with severe respiratory syncytial virus (RSV) bronchiolitis and 270 controls.0.049488432009TNF631575254GA
rs1800629244650307124TNFumls:C0004096BeFreeGSTP1 rs1138272 and TNF rs1800629 SNPs were associated with asthma and wheeze, respectively.0.2658279742014TNF631575254GA
rs1800629223760401493CTLA4umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0381961542012TNF631575254GA
rs1800629223760402206MS4A2umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0552223852012TNF631575254GA
rs1800629223760407124TNFumls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.2658279742012TNF631575254GA
rs1800629249366507124TNFumls:C0004096BeFreeAssociation between tumor necrosis factor-α rs1800629 polymorphism and risk of asthma: a meta-analysis.0.2658279742014TNF631575254GA
rs180088822075484154ADRB2umls:C0004096BeFreeWe tested the hypothesis that three functional polymorphisms in the ADRB2 gene (Thr164Ile, Gly16Arg and Gln27Glu) are associated with reduced lung function, asthma or chronic obstructive pulmonary disease (COPD).0.2687741092012ADRB25148827322CT
rs1800896241671513586IL10umls:C0004096BeFreePolymorphism of the rs1800896 IL10 promoter gene protects children from post-bronchiolitis asthma.0.1537102272013IL101206773552TC
rs18009251979619954738FEVumls:C0004096BeFreeIL13 SNPs rs1881457(-1512) and rs1800925(-1111) were associated with better FEV(1) and FEV(1)/FVC in asthmatics.0.0211724662010IL13;LOC1019277615132657117CT
rs1800925195540223596IL13umls:C0004096BeFreeIL13 encodes IL-13, a Th2 cytokine, and rs1800925 and rs20541 confer risk of asthma.0.4905192532009IL13;LOC1019277615132657117CT
rs1801274245865892212FCGR2Aumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0029957922014FCGR2A1161509955AG
rs1801274245865892213FCGR2Bumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0002714422014FCGR2A1161509955AG
rs1801274245865892214FCGR3Aumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0031813582014FCGR2A1161509955AG
rs1801275197702713566IL4Rumls:C0004096BeFreeOur findings indicate that the Q576R polymorphism directly promotes asthma in carrier populations by selectively augmenting IL-4R alpha-dependent signaling.0.1110138942009IL4R1627363079AG
rs1801275175362197124TNFumls:C0004096BeFreeWe aimed to investigate the association of the polymorphisms for IL-4 (C-589T), IL-4R alpha (Gln576Arg), TNF-alpha (G-308A) and LT-alpha (A252G) genes as candidates and asthma in adult Hong Kong Chinese population.0.2658279742007IL4R1627363079AG
rs1801275175362193566IL4Rumls:C0004096BeFreeWe aimed to investigate the association of the polymorphisms for IL-4 (C-589T), IL-4R alpha (Gln576Arg), TNF-alpha (G-308A) and LT-alpha (A252G) genes as candidates and asthma in adult Hong Kong Chinese population.0.1110138942007IL4R1627363079AG
rs1801275172842253566IL4Rumls:C0004096BeFreePolymorphisms in the interleukin-4 (C-590T), interleukin-4 receptor (ile50val and gln576arg), and interleukin-13 (arg130gln) genes have been described as susceptibility alleles for asthma.0.1110138942007IL4R1627363079AG
rs1801275225332352206MS4A2umls:C0004096BeFreeTo investigate whether the single-nucleotide polymorphisms (SNPs) Ile75Val and Gln576Arg in the IL4RA gene, -33C>T in the IL4 gene, and Gly237Glu in the FCER1B gene contribute to the development and severity of atopic bronchial asthma in Russian patients from Moscow.0.0552223852012IL4R1627363079AG
rs180273224248832792GNGT1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012GNGT1793908983AG
rs1805010225332352206MS4A2umls:C0004096BeFreeTo investigate whether the single-nucleotide polymorphisms (SNPs) Ile75Val and Gln576Arg in the IL4RA gene, -33C>T in the IL4 gene, and Gly237Glu in the FCER1B gene contribute to the development and severity of atopic bronchial asthma in Russian patients from Moscow.0.0552223852012IL4R1627344882AC,G,T
rs1805010223760401493CTLA4umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0381961542012IL4R1627344882AC,G,T
rs1805010223760407124TNFumls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.2658279742012IL4R1627344882AC,G,T
rs1805010223760402206MS4A2umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0552223852012IL4R1627344882AC,G,T
rs18372532180454991137SLC25A46umls:C0004096GAD[Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.]0.0047340642011NA5111066174TC
rs18372532180454891137SLC25A46umls:C0004096GAD[Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.]0.0047340642011NA5111066174TC
rs1861494183857423458IFNGumls:C0004096BeFreeIn conclusion, we report for the first time association of rs1861494 A/G polymorphism with asthma, which may regulate the IFNgamma levels and, hence, modulate asthma pathogenesis.0.0430484322008IFNG1268157629CT
rs18679822242488364072CDH23umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012CDH23;C10orf541071767290AG
rs18679822242488364115C10orf54umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012CDH23;C10orf541071767290AG
rs1871042213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011GSTP11167586373CT
rs1871042213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011GSTP11167586373CT
rs18814571979619954738FEVumls:C0004096BeFreeIL13 SNPs rs1881457(-1512) and rs1800925(-1111) were associated with better FEV(1) and FEV(1)/FVC in asthmatics.0.0211724662010IL13;LOC1019277615132656717AC
rs189212111022011149111CNIH3umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1224830399AG
rs19149731926497357628DPP10umls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.1116616862009DPP102114930953CT
rs1927911242437407099TLR4umls:C0004096BeFreeThe TLR4 single-nucleotide polymorphisms rs1927911, rs10759931, and rs6478317 modified the association of particulate matter and nitrogen dioxide with asthma.0.0579989362014TLR49117707776AG
rs19373952242488365217PCDH15umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012PCDH15;LOC1053783111054631543GA
rs1953367192649735729PTGDRumls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.0310950582009NA1452279352AG
rs1978331222062914048LTA4Humls:C0004096BeFreeThese data suggest that polymorphisms spanning ALOX5AP, LTA4H and the LTB4R locus are not major determinants of baseline lung function in smokers, but provide tentative evidence for LTA4H rs1978331C (intron 11) in determining baseline FEV1 and FEV1/FVC ratio in Caucasian Smokers in addition to our previously identified role in asthma susceptibility.0.0967310452011LTA4H1296015423AG
rs197833122206291241ALOX5APumls:C0004096BeFreeThese data suggest that polymorphisms spanning ALOX5AP, LTA4H and the LTB4R locus are not major determinants of baseline lung function in smokers, but provide tentative evidence for LTA4H rs1978331C (intron 11) in determining baseline FEV1 and FEV1/FVC ratio in Caucasian Smokers in addition to our previously identified role in asthma susceptibility.0.0241035832011LTA4H1296015423AG
rs1978331222062911241LTB4Rumls:C0004096BeFreeThese data suggest that polymorphisms spanning ALOX5AP, LTA4H and the LTB4R locus are not major determinants of baseline lung function in smokers, but provide tentative evidence for LTA4H rs1978331C (intron 11) in determining baseline FEV1 and FEV1/FVC ratio in Caucasian Smokers in addition to our previously identified role in asthma susceptibility.0.0046244432011LTA4H1296015423AG
rs1982073197451607040TGFB1umls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.2907425092010NANANANANA
rs198207319745160154ADRB2umls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.2687741092010NANANANANA
rs1982073197451607421VDRumls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.0177171242010NANANANANA
rs198372192649734878NPPAumls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.0077298562009NPPA111849457GA
rs199899897240537083596IL13umls:C0004096BeFreeIL-13 A2044G A/A and RANTES G-28C G/G have a significant and combined effect on the development of asthma.0.4905192532013IL135132658159GC
rs199899897240537086352CCL5umls:C0004096BeFreeIL-13 A2044G A/A and RANTES G-28C G/G have a significant and combined effect on the development of asthma.0.2587373172013IL135132658159GC
rs201961300171966414695NDUFA2umls:C0004096BeFreeTNF-alpha (-308 G/A) and CD14 (-159T/C) polymorphisms in the bronchial responsiveness of Korean children with asthma.0.0122148842007IK;NDUFA2;MIR36555140647891CT
rs20283731476769457379AICDAumls:C0004096BeFreeNeither the IFNG intron 1 CA repeat nor 465C/T of AICDA showed any association with asthma.0.007643982004AICDA128604885GA
rs2028373147676943458IFNGumls:C0004096BeFreeNeither the IFNG intron 1 CA repeat nor 465C/T of AICDA showed any association with asthma.0.0430484322004AICDA128604885GA
rs2038366206246517422VEGFAumls:C0004096BeFreeConsistent with predicted in silico functionality, alleles of the promoter SNPs rs2038366 (-1557G/T) and rs59317557 (-532C/G) influenced the activity of a luciferase S1PR1 reporter vector in transfected endothelial cells exposed to growth factors (epidermal growth factor, platelet-derived growth factor, and vascular endothelial growth factor) known to be increased in asthmatic airways.0.1479520892010S1PR1;LOC1019283701101235342GT
rs2038366206246511950EGFumls:C0004096BeFreeConsistent with predicted in silico functionality, alleles of the promoter SNPs rs2038366 (-1557G/T) and rs59317557 (-532C/G) influenced the activity of a luciferase S1PR1 reporter vector in transfected endothelial cells exposed to growth factors (epidermal growth factor, platelet-derived growth factor, and vascular endothelial growth factor) known to be increased in asthmatic airways.0.0010857672010S1PR1;LOC1019283701101235342GT
rs204993218045485089PBX2umls:C0004096GAD[Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.]0.1223670322011PBX2632187804AG
rs204993218045485089PBX2umls:C0004096GWASCATGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.0.1223670322011PBX2632187804AG
rs20541222862123596IL13umls:C0004096BeFreeEvidence for an association between EBV-negative cHL and rs20541 (5q31, IL13: OR = 1.53, 95% CI = 1.32 to 1.76, P = 5.4 x 10(-9)), a variant previously linked to psoriasis and asthma, was observed; however, the evidence for replication was less clear.0.4905192532012IL135132660272AG
rs20541223760407124TNFumls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.2658279742012IL135132660272AG
rs20541195540223596IL13umls:C0004096BeFreeIL13 encodes IL-13, a Th2 cytokine, and rs1800925 and rs20541 confer risk of asthma.0.4905192532009IL135132660272AG
rs20541223760401493CTLA4umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0381961542012IL135132660272AG
rs20541223760402206MS4A2umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0552223852012IL135132660272AG
rs20541226949303596IL13umls:C0004096BeFreeThe minor allele T of rs20541 in IL13 is the risk allele for asthma but the protective allele for psoriasis.0.4905192532012IL135132660272AG
rs2069408218045486490PMELumls:C0004096GWASCATGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.0.122011CDK21255970537AG
rs2069408218045481017CDK2umls:C0004096GAD[Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.]0.1223670322011CDK21255970537AG
rs2069408218045481017CDK2umls:C0004096GWASCATGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.0.1223670322011CDK21255970537AG
rs2069812188496143567IL5umls:C0004096BeFreeThe authors analyze the possible implication of 7 genetic polymorphisms described as asthma susceptibility genes: IL13 (C-1112T and R130Q), IL4RA (I50V, Q551R), IL5 (C-746T) and ADRB2 (Q27E and R16G) in specific olive pollen allergic sensitization.0.2454141262009IL55132544224AG
rs2069812173622543567IL5umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.2454141262007IL55132544224AG
rs2069812173622543562IL3umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.0103583982007IL55132544224AG
rs206981215805995450095PLFumls:C0004096BeFreeWe conducted an association study between known polymorphisms of IL-5 (T-746C) and TBXA2R (T924C) and asthma phenotype and the parameters of atopy and pulmonary function in atopic and nonatopic Korean children with asthma.0.013029212005IL55132544224AG
rs2069812173622541437CSF2umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.0159827332007IL55132544224AG
rs206981218849614154ADRB2umls:C0004096BeFreeThe authors analyze the possible implication of 7 genetic polymorphisms described as asthma susceptibility genes: IL13 (C-1112T and R130Q), IL4RA (I50V, Q551R), IL5 (C-746T) and ADRB2 (Q27E and R16G) in specific olive pollen allergic sensitization.0.2687741092009IL55132544224AG
rs20706002180454854738FEVumls:C0004096BeFreeWe observed the most significant association with adult asthma at rs404860 in the major histocompatiblity complex region (P = 4.07 × 10(-23)), which is close to rs2070600, a SNP previously reported for association with FEV(1)/FVC in genome-wide association studies for lung function.0.0211724662011AGER632183666CT
rs2070874236540773565IL4umls:C0004096BeFreeA total of 214 atopic patients (108 with asthma and 106 with allergic rhinitis) and 120 healthy controls from Pakistan were genotyped for IL-4 SNPs C-589T (rs2243250), T+2979G (rs2227284), and C-33T (rs2070874) using restriction fragment length polymorphism-polymerase chain reaction.0.354745832013IL45132674018CT
rs2070874248347743565IL4umls:C0004096BeFreeThe -33C/T polymorphism in the interleukin 4 gene is associated with asthma risk: a meta-analysis.0.354745832014IL45132674018CT
rs2070959195750271545CYP1B1umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0026384742009UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A92233693545AG
rs20709591957502754578UGT1A6umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0026384742009UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A92233693545AG
rs2070959195750275444PON1umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0029099162009UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A92233693545AG
rs2072446224687304804NGFRumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0026384742012NGFR;LOC100288866;MIR61651749510457CT
rs2072446224687302534FYNumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0056342662012NGFR;LOC100288866;MIR61651749510457CT
rs2073440206089213067HDCumls:C0004096BeFreeStatistically significant differences were observed for the histidine decarboxylase Glu644Asp (rs2073440) polymorphism, with OR (95% CI) values for homozygous carriers of the Glu644 allele equal to 3.12 (1.75-5.56, P < 0.00005) for all patients, 3.38 (1.54-7.44, P = 0.002) for patients with rhinitis alone, and 2.92 (1.43-5.95), P = 0.003 for patients with rhinitis + asthma, when compared with healthy controls.0.0052769482010HDC1550242317TG
rs2073643208605036584SLC22A5umls:C0004096GAD[Asthma is genetically heterogeneous. A few common alleles are associated with disease risk at all ages. Implicated genes suggest a role for communication of epithelial damage to the adaptive immune system and activation of airway inflammation. Variants at]0.1229099162010SLC22A55132387596TC
rs2073643208605036584SLC22A5umls:C0004096GWASCATA large-scale, consortium-based genomewide association study of asthma.0.1229099162010SLC22A55132387596TC
rs211954711022011220134SKA1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1850437594CT
rs21463232251996654738FEVumls:C0004096BeFreeConversely, the AA genotype in rs2146323 was associated with uncontrolled asthma in patients regularly receiving LTRA therapy (p = 0.020) and a worse FEV(1)/FVC ratio in patients who episodically used LTRA therapy (p = 0.044).0.0211724662012VEGFA643777358CA
rs2153101110220111116CHI3L1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.016806992000NA1203199346AT
rs2227284236540773565IL4umls:C0004096BeFreeA total of 214 atopic patients (108 with asthma and 106 with allergic rhinitis) and 120 healthy controls from Pakistan were genotyped for IL-4 SNPs C-589T (rs2243250), T+2979G (rs2227284), and C-33T (rs2070874) using restriction fragment length polymorphism-polymerase chain reaction.0.354745832013IL45132677033TG
rs222806518204779240ALOX5umls:C0004096BeFreeA novel polymorphism, E254K, in the 5-lipoxygenase gene associated with bronchial asthma.0.1708218952008ALOX51045425058GA,C
rs2228145235930363570IL6Rumls:C0004096BeFreeAlthough a common, non-synonymous variant in the IL-6 receptor gene (IL6R Asp358Ala; rs2228145 A>C) is associated with the risk of several common diseases, with the 358Ala allele conferring protection from coronary heart disease (CHD), rheumatoid arthritis (RA), atrial fibrillation (AF), abdominal aortic aneurysm (AAA), and increased susceptibility to asthma, the variant's effect on IL-6 signaling is not known.0.1305538952013IL6R1154454494AC,T
rs2228145225547043570IL6Rumls:C0004096BeFreeThe IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.0.1305538952012IL6R1154454494AC,T
rs2228145235930363569IL6umls:C0004096BeFreeAlthough a common, non-synonymous variant in the IL-6 receptor gene (IL6R Asp358Ala; rs2228145 A>C) is associated with the risk of several common diseases, with the 358Ala allele conferring protection from coronary heart disease (CHD), rheumatoid arthritis (RA), atrial fibrillation (AF), abdominal aortic aneurysm (AAA), and increased susceptibility to asthma, the variant's effect on IL-6 signaling is not known.0.0379907262013IL6R1154454494AC,T
rs2233287NA10318TNIP1umls:C0004096GADNA0.002638474NATNIP15151060536GA
rs2238631235170376625SNRNP70umls:C0004096BeFreeWe performed comprehensive sequencing of the TBXA2R gene in 48 Japanese control subjects and found a set of variants (SNP1 G>T rs2238634, SNP2 T>G rs2238633, SNP3 C>T rs2238632 and SNP4 G>A rs2238631) in intron 1 in linkage disequilibrium with c.795 T>C rs1131882, which was previously reported to be associated with asthma and related phenotypes.0.0005428842013TBXA2R193604301TC
rs2238632235170376625SNRNP70umls:C0004096BeFreeWe performed comprehensive sequencing of the TBXA2R gene in 48 Japanese control subjects and found a set of variants (SNP1 G>T rs2238634, SNP2 T>G rs2238633, SNP3 C>T rs2238632 and SNP4 G>A rs2238631) in intron 1 in linkage disequilibrium with c.795 T>C rs1131882, which was previously reported to be associated with asthma and related phenotypes.0.0005428842013TBXA2R193604500AG
rs2238633235170376625SNRNP70umls:C0004096BeFreeWe performed comprehensive sequencing of the TBXA2R gene in 48 Japanese control subjects and found a set of variants (SNP1 G>T rs2238634, SNP2 T>G rs2238633, SNP3 C>T rs2238632 and SNP4 G>A rs2238631) in intron 1 in linkage disequilibrium with c.795 T>C rs1131882, which was previously reported to be associated with asthma and related phenotypes.0.0005428842013TBXA2R193604551CA
rs2238634235170376625SNRNP70umls:C0004096BeFreeWe performed comprehensive sequencing of the TBXA2R gene in 48 Japanese control subjects and found a set of variants (SNP1 G>T rs2238634, SNP2 T>G rs2238633, SNP3 C>T rs2238632 and SNP4 G>A rs2238631) in intron 1 in linkage disequilibrium with c.795 T>C rs1131882, which was previously reported to be associated with asthma and related phenotypes.0.0005428842013TBXA2R193604731AC
rs223918519745160154ADRB2umls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.2687741092010VDR;LOC1053697491247850776GA
rs2239185197451607040TGFB1umls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.2907425092010VDR;LOC1053697491247850776GA
rs2239185197451607421VDRumls:C0004096BeFreeProposed test statistics are applied to NHANES III data to test for associations between the locus ADRB2 (rs1042713) and obesity, between VDR (rs2239185) and high blood lead level, and between TGFB1 (rs1982073) and asthma.0.0177171242010VDR;LOC1053697491247850776GA
rs22400172017580330009TBX21umls:C0004096BeFreePharmacogenetic study of the effects of NK2R G231E G>A and TBX21 H33Q C>G polymorphisms on asthma control with inhaled corticosteroid treatment.0.1504524852009TBX211747733553CG
rs22400172017580354738FEVumls:C0004096BeFreeOur results suggest that NK2R G231E G>A and TBX21 H33Q C>G are genetic predictors of response to ICS, at least with respect to asthma control status and changes in FEV(1)%, in Korean patients with asthma.0.0211724662009TBX211747733553CG
rs2240017201758036865TACR2umls:C0004096BeFreePharmacogenetic study of the effects of NK2R G231E G>A and TBX21 H33Q C>G polymorphisms on asthma control with inhaled corticosteroid treatment.0.005548392009TBX211747733553CG
rs2243250175362193566IL4Rumls:C0004096BeFreeWe aimed to investigate the association of the polymorphisms for IL-4 (C-589T), IL-4R alpha (Gln576Arg), TNF-alpha (G-308A) and LT-alpha (A252G) genes as candidates and asthma in adult Hong Kong Chinese population.0.1110138942007IL45132673462CT
rs2243250223760402206MS4A2umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0552223852012IL45132673462CT
rs2243250183960273565IL4umls:C0004096BeFreeAssociation between C-589T polymorphisms of interleukin-4 gene promoter and asthma: a meta-analysis.0.354745832008IL45132673462CT
rs2243250255377963565IL4umls:C0004096BeFreeInterleukin-4 -589C/T Polymorphism is Associated with Increased Pediatric Asthma Risk: A Meta-Analysis.0.354745832016IL45132673462CT
rs2243250226524163565IL4umls:C0004096BeFreeInterleukin-4 rs2243250 polymorphism is associated with asthma among Caucasians and related to atopic asthma.0.354745832012IL45132673462CT
rs2243250233987893565IL4umls:C0004096BeFreeAssociation between the interleukin-4 gene C-589T and C+33T polymorphisms and asthma risk: a meta-analysis.0.354745832013IL45132673462CT
rs2243250236540773565IL4umls:C0004096BeFreeA total of 214 atopic patients (108 with asthma and 106 with allergic rhinitis) and 120 healthy controls from Pakistan were genotyped for IL-4 SNPs C-589T (rs2243250), T+2979G (rs2227284), and C-33T (rs2070874) using restriction fragment length polymorphism-polymerase chain reaction.0.354745832013IL45132673462CT
rs2243250223760407124TNFumls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.2658279742012IL45132673462CT
rs2243250180880173565IL4umls:C0004096BeFreeAssociation of TNF-alpha -308 G/A and IL-4 -589 C/T gene promoter polymorphisms with asthma susceptibility in the south of Iran.0.354745832007IL45132673462CT
rs2243250223760401493CTLA4umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0381961542012IL45132673462CT
rs2243250175362197124TNFumls:C0004096BeFreeWe aimed to investigate the association of the polymorphisms for IL-4 (C-589T), IL-4R alpha (Gln576Arg), TNF-alpha (G-308A) and LT-alpha (A252G) genes as candidates and asthma in adult Hong Kong Chinese population.0.2658279742007IL45132673462CT
rs2243250234546223565IL4umls:C0004096BeFreeThe interleukin-4 -589C/T polymorphism and the risk of asthma: a meta-analysis including 7,345 cases and 7,819 controls.0.354745832013IL45132673462CT
rs22440122012508810111RAD50umls:C0004096GAD[Genome-wide association study of recurrent early-onset major depressive disorder.]0.2463627152011RAD505132565533AG
rs22440122015924210111RAD50umls:C0004096GAD[Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.]0.2463627152010RAD505132565533AG
rs2244012201592423596IL13umls:C0004096BeFreeMultiple SNPs in the RAD50-IL13 region on chromosome 5q31.1 were associated with asthma: rs2244012 in intron 2 of RAD50 (P = 3.04E-07).0.4905192532010RAD505132565533AG
rs22440122015924210111RAD50umls:C0004096BeFreeMultiple SNPs in the RAD50-IL13 region on chromosome 5q31.1 were associated with asthma: rs2244012 in intron 2 of RAD50 (P = 3.04E-07).0.2463627152010RAD505132565533AG
rs22440122015924210111RAD50umls:C0004096GWASCATGenome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.0.2463627152010RAD505132565533AG
rs2249003NA4153MBL2umls:C0004096GADNA0.031747563NALOC1053783091053005848AC
rs2275913204372533605IL17Aumls:C0004096BeFreeThe preliminary results demonstrate that IL-17 SNP rs2275913 was associated with several asthma-related traits and confers genetic susceptibility to childhood asthma.0.1001501692010IL17A652186235GA
rs2275913243930793605IL17Aumls:C0004096BeFreeWe investigated the possible association among asthma and IL-17A -197G/A (rs2275913), IL-17F 7488A/G (rs763780) and IL-17F 7383A/G (rs2397084).0.1001501692014IL17A652186235GA
rs2276109200189594321MMP12umls:C0004096BeFreeThe minor allele of a SNP in MMP12 (rs2276109) is associated with a positive effect on lung function in children with asthma and in adults who smoke.0.0060912732009MMP1211102875061TC
rs22761092001895954738FEVumls:C0004096BeFreeThe minor allele (G) of a functional variant in the promoter region of MMP12 (rs2276109 [-82A-->G]) was positively associated with FEV(1) in a combined analysis of children with asthma and adult former and current smokers in all cohorts (P=2x10(-6)).0.0211724662009MMP1211102875061TC
rs2277460253759075706PSMC6umls:C0004096BeFreeTo investigate polymorphisms of proteasomal genes PSMA6 (rs1048990 and rs2277460), PSMC6 (rs2295826 and rs2295827) and PSMA3 (rs2348071) in Lithuanian patients with asthma.0.0002714422015PSMA61435292367CT,A
rs22820321102201155051NRDE2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NRDE21490292547GT
rs2284033208605033560IL2RBumls:C0004096GAD[We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3A10(a9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7A10(a14)); rs1342326 on chromosome 9, flanking IL33 (P=9A10(a10)); rs744910 on chromosome 15 in SMAD3 (P=4A10(a9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1A10(a8)).]0.1279154222010IL2RB2237137994GA
rs2284033208605033560IL2RBumls:C0004096GWASCATWe observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).0.1279154222010IL2RB2237137994GA
rs22904011022011116159CYYR1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA2126835071AC
rs22904002262659222806IKZF3umls:C0004096BeFreeSixteen SNPs were significantly associated with asthma after multiple testing correction (P ≤ .01), of which 5 (rs2290400, rs8079416, rs3894194, rs7212938, and rs3859192) were strongly associated (FDR P ≤ .0002), and one was novel (IKZF3-rs1453559).0.1210857672012GSDMB1739909987TC
rs2290400NA55876GSDMBumls:C0004096GADNA0.263279326NAGSDMB1739909987TC
rs229185520580442255061TAC4umls:C0004096BeFreeA significant association with asthma was observed for two SNPs: rs2291855 in the TAC3 gene conferring asthma protection (Odds ratio [OR]: 0.46; 95% Confidence Interval [CI]: 0.22-0.97; P=0.038), and rs4794068 in the TAC4 gene associated with an increased risk for asthma (OR: 1.94; 95% CI: 1.06-3.54; P=0.03).0.0026384742010TAC31257016407GA
rs2291855205804426866TAC3umls:C0004096BeFreeA significant association with asthma was observed for two SNPs: rs2291855 in the TAC3 gene conferring asthma protection (Odds ratio [OR]: 0.46; 95% Confidence Interval [CI]: 0.22-0.97; P=0.038), and rs4794068 in the TAC4 gene associated with an increased risk for asthma (OR: 1.94; 95% CI: 1.06-3.54; P=0.03).0.0026384742010TAC31257016407GA
rs2295826253759075706PSMC6umls:C0004096BeFreeTo investigate polymorphisms of proteasomal genes PSMA6 (rs1048990 and rs2277460), PSMC6 (rs2295826 and rs2295827) and PSMA3 (rs2348071) in Lithuanian patients with asthma.0.0002714422015PSMC61452708205AG
rs2295827253759075706PSMC6umls:C0004096BeFreeTo investigate polymorphisms of proteasomal genes PSMA6 (rs1048990 and rs2277460), PSMC6 (rs2295826 and rs2295827) and PSMA3 (rs2348071) in Lithuanian patients with asthma.0.0002714422015PSMC61452708263CT
rs2297515110220114843NOS2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.2327237092000NOS21727766307AC
rs23030671582049411005SPINK5umls:C0004096BeFreeDevelopment of a high throughput assay to analyse the polymorphism G1258A (Glu420Lys) in exon 14 of the SPINK5 gene followed by the validation using samples of 235 latex-allergic health care workers (HCWs) with (N=63) and without asthma (N=172), and 80 non-atopic controls.0.0211077912005SPINK55148101392AG
rs23054802424153755876GSDMBumls:C0004096GWASCATFour of these, GSDMB, IL33, RAD50 and IL1RL1, were previously reported as asthma susceptibility loci, but the effect sizes for these loci in our cohort were considerably larger than in the previous genome-wide association studies of asthma.0.2632793262013GSDMB1739905943GA
rs23054802086050355876GSDMBumls:C0004096GWASCATA large-scale, consortium-based genomewide association study of asthma.0.2632793262010GSDMB1739905943GA
rs23054802246906255876GSDMBumls:C0004096BeFreeTo assess whether the association of rs2305480 on chromosome 17q12 in the GSDML gene with asthma-like symptoms in the first 4 years of life is modified by smoke exposure during fetal and early postnatal life.0.2632793262012GSDMB1739905943GA
rs23054802086050355876GSDMBumls:C0004096GAD[Asthma is genetically heterogeneous. A few common alleles are associated with disease risk at all ages. Implicated genes suggest a role for communication of epithelial damage to the adaptive immune system and activation of airway inflammation. Variants at]0.2632793262010GSDMB1739905943GA
rs231775223760407124TNFumls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.2658279742012CTLA42203867991AG,T
rs231775223760401493CTLA4umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0381961542012CTLA42203867991AG,T
rs231775223760402206MS4A2umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0552223852012CTLA42203867991AG,T
rs2348071253759075706PSMC6umls:C0004096BeFreeTo investigate polymorphisms of proteasomal genes PSMA6 (rs1048990 and rs2277460), PSMC6 (rs2295826 and rs2295827) and PSMA3 (rs2348071) in Lithuanian patients with asthma.0.0002714422015PSMA31458263908AG
rs23812892081531210333TLR6umls:C0004096BeFreeFurthermore, a positive association was observed between the T allele of rs2381289 in TLR6 and allergic rhinitis in asthma (OR, 1.79; 95% CI, 1.10-2.91; P = .025), while the A allele of rs11466651 in TLRIO was negatively associated with allergic rhinitis (OR, 0.49; 95% CI, 0.26-0.95; P = .046).0.020736662010TLR6438825250GA
rs23814162180454926953RANBP6umls:C0004096GAD[Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.]0.0047340642011NA96193455CA
rs23830242242488354875CNTLNumls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012CNTLN917487947TG
rs2395185226949303122HLA-DRAumls:C0004096BeFreeThe minor allele T of rs2395185 in HLA-DRA is the risk allele for asthma but the protective allele for ulcerative colitis.0.0058198312012NA632465390GT
rs2397084243930793605IL17Aumls:C0004096BeFreeWe investigated the possible association among asthma and IL-17A -197G/A (rs2275913), IL-17F 7488A/G (rs763780) and IL-17F 7383A/G (rs2397084).0.1001501692014IL17F;LOC105375088652237046TC
rs24242342242488357419SLC24A3umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012SLC24A32019383335TC
rs2495636223760401493CTLA4umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0381961542012IL13RA1X118791935AG
rs2495636223760402206MS4A2umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0552223852012IL13RA1X118791935AG
rs2495636223760407124TNFumls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.2658279742012IL13RA1X118791935AG
rs256919020608916929CD14umls:C0004096GAD[The effect of CD14 C159T polymorphism on in vitro IgE synthesis and cytokine production by PBMC from children with asthma.]0.2148378812011CD14;TMCO65140633331AG
rs2569190223760401493CTLA4umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0381961542012CD14;TMCO65140633331AG
rs2569190223760407124TNFumls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.2658279742012CD14;TMCO65140633331AG
rs2569190223760402206MS4A2umls:C0004096BeFreeTo investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.0.0552223852012CD14;TMCO65140633331AG
rs25882173622543567IL5umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.2454141262007CSF25132075767TC
rs25882173622543562IL3umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.0103583982007CSF25132075767TC
rs25882173622541437CSF2umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.0159827332007CSF25132075767TC
rs259892110220111794DOCK2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000DOCK2;FAM196B5169930499TG
rs25989211022011100131897FAM196Bumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000DOCK2;FAM196B5169930499TG
rs26237022242488364478CSMD1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0026384742012CSMD183737384TC
rs265878222424883159989CCDC67umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012CCDC671193433565TG
rs266292811022011149111CNIH3umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1224823940AG
rs2668898110220117439BEST1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000BEST11161958026AT,G
rs2706347217344005791PTPREumls:C0004096BeFreeRAD50 (rs2706347) and PTPRE (rs10830196) revealed crude associations with asthma at a Bonferroni-corrected level of significance (p < 0.0011).0.0029099162011RAD505132569425GT
rs272783116815140313AOAHumls:C0004096GAD[Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes.]0.0029099162006AOAH736577011TC
rs2780885218273233716JAK1umls:C0004096BeFreeJAK-1 rs2780895 C-related genotype and allele but not JAK-1 rs10789166, rs4916008, rs2780885, rs17127114, and rs3806277 are associated with higher susceptibility to asthma.0.0026384742011JAK1164865689CT
rs2780895218273233716JAK1umls:C0004096BeFreeJAK-1 rs2780895 C-related genotype and allele but not JAK-1 rs10789166, rs4916008, rs2780885, rs17127114, and rs3806277 are associated with higher susceptibility to asthma.0.0026384742011JAK1164843717CT
rs27860982003231823418CRB1umls:C0004096GWASCATVariants of DENND1B associated with asthma in children.0.1223670322010CRB11197356778TG,A
rs27860982003231823418CRB1umls:C0004096GAD[We have identified a locus containing DENND1B on chromosome 1q31.3 that is associated with susceptibility to asthma.]0.1223670322010CRB11197356778TG,A
rs278609820032318163486DENND1Bumls:C0004096GAD[We have identified a locus containing DENND1B on chromosome 1q31.3 that is associated with susceptibility to asthma.]0.005548392010CRB11197356778TG,A
rs28364072179804182208FCER2umls:C0004096GAD[FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma.]0.0098155152007FCER2197690399AG
rs2844484200492127124TNFumls:C0004096BeFreeThe association between modeled NO(2) and asthma prevalence was significant for carriers of the most common genotypes of NQO1 rs2917666 [odds ratio (OR) = 1.54; 95% confidence interval (CI), 1.10-2.24], TNFA rs2844484 (OR = 2.02; 95% CI, 1.30-3.27).0.2658279742009LTA;LOC100287329631568447AG
rs28516871102201126011TENM4umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000LOC1019289891182064908TG,C
rs28665122220692703606IL18umls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.036076822011VIMP15101277522CT
rs286651222206927055829VIMPumls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.0002714422011VIMP15101277522CT
rs28725072107218794103ORMDL3umls:C0004096BeFreeIn addition, rs2872507, which maps to a locus associated with asthma and influences the expression of the ORMDL3 gene in lymphoblastoid cells, showed a significant association with AS (p = 0.03).0.1723409262010NA1739884510GA
rs28725072269493055876GSDMBumls:C0004096BeFreeThe minor allele A of rs2872507 in GSDMB is the protective allele for asthma but the risk allele for rheumatoid arthritis, Crohn disease, and ulcerative colitis.0.2632793262012NA1739884510GA
rs2915863249027624695NDUFA2umls:C0004096BeFreeWe observed two interactions between SNPs in CD14 and LY96 with environmental endotoxin exposure in relation to hospital admissions due to asthma exacerbation which remained significant after correction for multiple testing (CD14 SNPs rs2915863 and LY96 SNP rs17226566).0.0122148842014CD14;TMCO65140634792CT
rs29158632490276223643LY96umls:C0004096BeFreeWe observed two interactions between SNPs in CD14 and LY96 with environmental endotoxin exposure in relation to hospital admissions due to asthma exacerbation which remained significant after correction for multiple testing (CD14 SNPs rs2915863 and LY96 SNP rs17226566).0.0002714422014CD14;TMCO65140634792CT
rs2917666200492127124TNFumls:C0004096BeFreeThe association between modeled NO(2) and asthma prevalence was significant for carriers of the most common genotypes of NQO1 rs2917666 [odds ratio (OR) = 1.54; 95% confidence interval (CI), 1.10-2.24], TNFA rs2844484 (OR = 2.02; 95% CI, 1.30-3.27).0.2658279742009NA1669730057CG
rs29811926497351131PHF11umls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.1507476722009PHF111349526958GA
rs301988521814517441376AARDumls:C0004096GAD[Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.]0.0023670322011SLC30A88117013406TG
rs301988521814517169026SLC30A8umls:C0004096GAD[Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.]0.1223670322011SLC30A88117013406TG
rs301988521814517169026SLC30A8umls:C0004096GWASCATGenome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.0.1223670322011SLC30A88117013406TG
rs3021094192649733586IL10umls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.1537102272009IL101206771607TG
rs311709821804548414764HCG23umls:C0004096GWASCATGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.0.122011HCG23;LOC101929163632390736GA
rs3129890218045483122HLA-DRAumls:C0004096GAD[Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.]0.0058198312011NA632446496TC
rs31299432180454810665C6orf10umls:C0004096GAD[Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.]0.1223670322011C6orf10;LOC101929163632370918AG
rs31299432180454810665C6orf10umls:C0004096GWASCATGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.0.1223670322011C6orf10;LOC101929163632370918AG
rs3209951677667410800CYSLTR1umls:C0004096BeFreeA TaqMan allelic discrimination assay was used to genotype a 927T/C SNP and oligonucleotide ligation assays were used to genotype the previously reported 617T/C and 898G/A SNPs of CYSLTR1 in 341 asthmatic families from the UK.0.054717892006CYSLTR1X78272820GT,A
rs320995188296838795TNFRSF10Bumls:C0004096BeFreeIn the initial sample, three SNPs, rs320995 in the cysteinyl leukotriene receptor 1 gene, rs1047266 in the tumour necrosis factor receptor superfamily, member 10b, gene and rs40401 in the interleukin-3 gene, were associated with risk of asthma.0.0002714422009CYSLTR1X78272820GT,A
rs320995188296833562IL3umls:C0004096BeFreeIn the initial sample, three SNPs, rs320995 in the cysteinyl leukotriene receptor 1 gene, rs1047266 in the tumour necrosis factor receptor superfamily, member 10b, gene and rs40401 in the interleukin-3 gene, were associated with risk of asthma.0.0103583982009CYSLTR1X78272820GT,A
rs3212227215137523593IL12Bumls:C0004096BeFreeThese results suggest that the SNPs in IL-12A rs568404 and IL-12B rs3212227 may individually and jointly contribute to the risk of asthma in a Chinese population.0.1542004712011IL12B5159315942TG
rs32498116790440387129NPSR1umls:C0004096BeFreeStructure-function relationships in the neuropeptide S receptor: molecular consequences of the asthma-associated mutation N107I.0.1825957542006NPSR1;NPSR1-AS1734778501AT
rs345065NA5021OXTRumls:C0004096GADNA0.002638474NAOXTR38821239TC
rs351414842382968651088KLHL5umls:C0004096GWASCATRank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.0.122013KLHL5;LOC105374418439086721AC
rs360717220692703606IL18umls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.036076822011IL1811112164002GA
rs3607172206927055829VIMPumls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.0002714422011IL1811112164002GA
rs3730353224687304804NGFRumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0026384742012FYN6111674463AG
rs3730353224687302534FYNumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0056342662012FYN6111674463AG
rs37307291102201111201POLIumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000POLI1854278332CT
rs3732378205233026376CX3CL1umls:C0004096BeFreeThe CX3CR1 gene encodes the fractalkine (CX3CL1) receptor and has two coding single-nucleotide polymorphisms, V249I and T280M, linked to a lower risk of other inflammatory diseases such as coronary artery disease (CAD) and asthma.0.0005428842011CX3CR1339265671GA
rs3732378205233021524CX3CR1umls:C0004096BeFreeThe CX3CR1 gene encodes the fractalkine (CX3CL1) receptor and has two coding single-nucleotide polymorphisms, V249I and T280M, linked to a lower risk of other inflammatory diseases such as coronary artery disease (CAD) and asthma.0.008272742011CX3CR1339265671GA
rs3732379205233021524CX3CR1umls:C0004096BeFreeThe CX3CR1 gene encodes the fractalkine (CX3CL1) receptor and has two coding single-nucleotide polymorphisms, V249I and T280M, linked to a lower risk of other inflammatory diseases such as coronary artery disease (CAD) and asthma.0.008272742011CX3CR1339265765CT
rs3732379205233026376CX3CL1umls:C0004096BeFreeThe CX3CR1 gene encodes the fractalkine (CX3CL1) receptor and has two coding single-nucleotide polymorphisms, V249I and T280M, linked to a lower risk of other inflammatory diseases such as coronary artery disease (CAD) and asthma.0.0005428842011CX3CR1339265765CT
rs374287921039601384ARG2umls:C0004096BeFreeThe ARG2 association was tagged by intronic variant rs3742879 with stronger association with FeNO in asthmatic children (P-interaction = 0.01).0.1266341572011ARG21467648284AG
rs3742879210396014843NOS2umls:C0004096BeFreeThe association of a NOS2A promoter haplotype with FeNO varied significantly by rs3742879 genotypes and by asthma.0.2327237092011ARG21467648284AG
rs374874811022011255104TMCO4umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000TMCO4119691702GA
rs3771166208605038809IL18R1umls:C0004096GWASCATWe observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).0.1426367532010IL18R12102369762GA
rs3771166208605038809IL18R1umls:C0004096GAD[We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3A10(a9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7A10(a14)); rs1342326 on chromosome 9, flanking IL33 (P=9A10(a10)); rs744910 on chromosome 15 in SMAD3 (P=4A10(a9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1A10(a8)).]0.1426367532010IL18R12102369762GA
rs3771180230284839173IL1RL1umls:C0004096BeFreeWe also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus.0.2670894442012IL1RL12102337157GT
rs3771180218045499173IL1RL1umls:C0004096GAD[Four were at previously reported loci on 17q21, near IL1RL1, TSLP and IL33, but we report for the first time, to our knowledge, that these loci are associated with asthma risk in three ethnic groups.]0.2670894442011IL1RL12102337157GT
rs3771180218045499173IL1RL1umls:C0004096GWASCATFour were at previously reported loci on 17q21, near IL1RL1, TSLP and IL33, but we report for the first time, to our knowledge, that these loci are associated with asthma risk in three ethnic groups.0.2670894442011IL1RL12102337157GT
rs3771180230284838809IL18R1umls:C0004096BeFreeWe also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus.0.1426367532012IL1RL12102337157GT
rs3785931224687304804NGFRumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0026384742012NGFR1749500756TC
rs3785931224687302534FYNumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0056342662012NGFR1749500756TC
rs3792785NA10318TNIP1umls:C0004096GADNA0.002638474NATNIP15151072089TC
rs3797325134782113263GLCCI1umls:C0004096BeFreeRs37972 and rs37973 variants in the glucocorticoid-induced transcript 1 gene have been associated with inhaled glucocorticosteroid responsiveness in asthmatics; however, some discrepancies have been also reported.0.0016286512015GLCCI1;LOC100505921;LOC10537513977968245GA
rs3805236218045482549GAB1umls:C0004096GWASCATGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.0.1202714422011GAB14143436584AG
rs3806277218273233716JAK1umls:C0004096BeFreeJAK-1 rs2780895 C-related genotype and allele but not JAK-1 rs10789166, rs4916008, rs2780885, rs17127114, and rs3806277 are associated with higher susceptibility to asthma.0.0026384742011JAK1164887247CT
rs3809865234511095018OXA1Lumls:C0004096BeFreeOur results revealed that rs3809865 was significantly associated with asthma due to its effect on the binding of hsa-mir-124 to ITGB3.0.0002714422013ITGB3;LOC1027245081747311220TA
rs384330622424883343472BARHL2umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012LOC105378853190822573TA
rs38591922262659222806IKZF3umls:C0004096BeFreeSixteen SNPs were significantly associated with asthma after multiple testing correction (P ≤ .01), of which 5 (rs2290400, rs8079416, rs3894194, rs7212938, and rs3859192) were strongly associated (FDR P ≤ .0002), and one was novel (IKZF3-rs1453559).0.1210857672012GSDMA1739972395CT
rs386596107166301486648SOD2umls:C0004096BeFreeTo investigate the association of the manganese-containing form of SOD (MnSOD) gene at amino acid position 16 (Val16Ala) and catalase gene in the promoter at A-21T and C-262T polymorphisms and asthma in a Hong Kong Chinese population.0.0058198312006NANANANANA
rs386599440244958602206MS4A2umls:C0004096BeFreeAssociation of the MS4A2 gene promoter C-109T or the 7th exon E237G polymorphisms with asthma risk: a meta-analysis.0.0552223852014NANANANANA
rs386599440189318922206MS4A2umls:C0004096BeFreeCD14-159 C/T and MS4A2 Glu237Gly were identified to have difference in genotype/allele frequencies between the control group and asthma patients.0.0552223852009NANANANANA
rs386599440225332352206MS4A2umls:C0004096BeFreeTo investigate whether the single-nucleotide polymorphisms (SNPs) Ile75Val and Gln576Arg in the IL4RA gene, -33C>T in the IL4 gene, and Gly237Glu in the FCER1B gene contribute to the development and severity of atopic bronchial asthma in Russian patients from Moscow.0.0552223852012NANANANANA
rs389419420860503284110GSDMAumls:C0004096GWASCATA large-scale, consortium-based genomewide association study of asthma.0.1237242412010GSDMA1739965740GA
rs389419420860503284110GSDMAumls:C0004096GAD[Asthma is genetically heterogeneous. A few common alleles are associated with disease risk at all ages. Implicated genes suggest a role for communication of epithelial damage to the adaptive immune system and activation of airway inflammation. Variants at]0.1237242412010GSDMA1739965740GA
rs38941942262659222806IKZF3umls:C0004096BeFreeSixteen SNPs were significantly associated with asthma after multiple testing correction (P ≤ .01), of which 5 (rs2290400, rs8079416, rs3894194, rs7212938, and rs3859192) were strongly associated (FDR P ≤ .0002), and one was novel (IKZF3-rs1453559).0.1210857672012GSDMA1739965740GA
rs389419424241537284110GSDMAumls:C0004096GWASCATA genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.0.1237242412013GSDMA1739965740GA
rs39121612134637054738FEVumls:C0004096BeFreeIn addition, a polymorphism in intron 4 (rs3912161) and a haplotype (SLC22A2-ht3) showed significantly stronger association signals with the FEV(1) fall rate induced by aspirin provocation in AIA subjects compared with ATA controls (p = 0.004, P(corr) = 0.05).0.0211724662011SLC22A26160248686TC
rs396991245865892214FCGR3Aumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0031813582014FCGR3A1161544752AG,C
rs396991245865892213FCGR2Bumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0002714422014FCGR3A1161544752AG,C
rs396991245865892212FCGR2Aumls:C0004096BeFreeFunctional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B (FcγRIIB-187Ile>Thr, rs1050501), FCGR2C (FcγRIIC-13Gln>Stop, rs10917661), FCGR3A (FcγRIIIA-158Val>Phe, rs396991), and FCGR3B variants (FcγRIIIB NA1 and NA2) were genotyped in an asthma family cohort including 370 atopy positive, 239 atopy negative, and 169 asthma positive subjects.0.0029957922014FCGR3A1161544752AG,C
rs40401173622541437CSF2umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.0159827332007IL3;LOC1053791745132060785CT
rs40401242933943562IL3umls:C0004096BeFreeThe strongest hypothetical biological mechanism was one wherein SNPrs40401 modulates the role of IL3 in several pathways and conditions, including the stem pathway, asthma (hsa05310), the dendritic cell pathway, and development (0.001 < p < 0.004; 0.001 < FDR < 0.033).0.0103583982013IL3;LOC1053791745132060785CT
rs40401188296833562IL3umls:C0004096BeFreeIn the initial sample, three SNPs, rs320995 in the cysteinyl leukotriene receptor 1 gene, rs1047266 in the tumour necrosis factor receptor superfamily, member 10b, gene and rs40401 in the interleukin-3 gene, were associated with risk of asthma.0.0103583982009IL3;LOC1053791745132060785CT
rs40401246845173562IL3umls:C0004096BeFreeIL3 rs40401 polymorphism and interaction with smoking in risk of asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health study.0.0103583982014IL3;LOC1053791745132060785CT
rs40401173622543567IL5umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.2454141262007IL3;LOC1053791745132060785CT
rs40401173622543562IL3umls:C0004096BeFreeIn two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).0.0103583982007IL3;LOC1053791745132060785CT
rs40401188296838795TNFRSF10Bumls:C0004096BeFreeIn the initial sample, three SNPs, rs320995 in the cysteinyl leukotriene receptor 1 gene, rs1047266 in the tumour necrosis factor receptor superfamily, member 10b, gene and rs40401 in the interleukin-3 gene, were associated with risk of asthma.0.0002714422009IL3;LOC1053791745132060785CT
rs404860218045484855NOTCH4umls:C0004096GAD[Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.]0.1223670322011NOTCH4632216568TC
rs4048602180454854738FEVumls:C0004096BeFreeWe observed the most significant association with adult asthma at rs404860 in the major histocompatiblity complex region (P = 4.07 × 10(-23)), which is close to rs2070600, a SNP previously reported for association with FEV(1)/FVC in genome-wide association studies for lung function.0.0211724662011NOTCH4632216568TC
rs404860218045484855NOTCH4umls:C0004096GWASCATGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.0.1223670322011NOTCH4632216568TC
rs4129267219078643570IL6Rumls:C0004096GWASCATIdentification of IL6R and chromosome 11q13.5 as risk loci for asthma.0.1305538952011IL6R1154453788CT
rs4129267219078641258CNGB1umls:C0004096BeFreeTwo loci were confirmed to associate with asthma risk in the replication cohorts and reached genome-wide significance in the combined analysis of all available studies (n=57,800): rs4129267 (OR 1·09, combined p=2·4×10(-8)) in the interleukin-6 receptor (IL6R) gene and rs7130588 (OR 1·09, p=1·8×10(-8)) on chromosome 11q13.5 near the leucine-rich repeat containing 32 gene (LRRC32, also known as GARP).0.0002714422011IL6R1154453788CT
rs4129267219078643570IL6Rumls:C0004096GAD[Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.]0.1305538952011IL6R1154453788CT
rs41295115243880133559IL2RAumls:C0004096BeFreeSingle nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).0.0890771342013NA106082658TC
rs41295115243880137145TNS1umls:C0004096BeFreeSingle nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).0.1205428842013NA106082658TC
rs4130140110220119501RPH3ALumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000LOC10537143017407766GA
rs413476481451506357105CYSLTR2umls:C0004096BeFreeThe novel M201V [corrected] CysLT2 receptor variant was associated with atopy (21%) on Tristan da Cunha compared with those who were non-atopic (7%) (Fisher's exact test, P=0.0016) in a manner that was independent of asthma (two-way ANOVA, P=0.0015).0.0187170152003CYSLTR21348707418AG
rs41347648145150634858NOVA2umls:C0004096BeFreeThe novel M201V [corrected] CysLT2 receptor variant was associated with atopy (21%) on Tristan da Cunha compared with those who were non-atopic (7%) (Fisher's exact test, P=0.0016) in a manner that was independent of asthma (two-way ANOVA, P=0.0015).0.0008143262003CYSLTR21348707418AG
rs415348472333152580332ADAM33umls:C0004096BeFreeSeventeen SNPs were significantly associated with asthma; one (rs41534847 in ADAM33) remained significant after correction for multiple testing.0.1049334312013ADAM33203673835GA
rs4253238242496363818KLKB1umls:C0004096BeFreeIn these cohorts, a genome-wide association study of serum scuPAR levels identified a human plasma kallikrein gene (KLKB1) promoter polymorphism (rs4253238) associated with serum scuPAR levels in a control/asthma population (P=1.17 × 10(-7)), which was also observed in a COPD population (combined P=5.04 × 10(-12)).0.0002714422014KLKB14186227233CT
rs4271002236220084780NFE2L2umls:C0004096BeFreeGene polymorphisms in NAT2 (rs4271002), Nrf2 (rd6726395), and GSTP1 (rd1695) increased the risk of treatment for asthma within the last 12 months.0.0042671252013NAT2818390758GC
rs42710022362200881539SLC38A1umls:C0004096BeFreeGene polymorphisms in NAT2 (rs4271002), Nrf2 (rd6726395), and GSTP1 (rd1695) increased the risk of treatment for asthma within the last 12 months.0.0019000932013NAT2818390758GC
rs4271002236220082950GSTP1umls:C0004096BeFreeGene polymorphisms in NAT2 (rs4271002), Nrf2 (rd6726395), and GSTP1 (rd1695) increased the risk of treatment for asthma within the last 12 months.0.2239365422013NAT2818390758GC
rs43089241102201157568SIPA1L2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1232691597TC
rs43786501913392155876GSDMBumls:C0004096BeFreeWe genotyped rs4378650 in ORMDL3 and rs7216389 in GSDML in 615 nuclear families consisting of asthmatic children aged 4-17 years and their parents.0.2632793262009NANANANANA
rs443198411022011159963SLC5A12umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1126874358CT
rs4436440110220111999ELF3umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA1202082885TA
rs45123421839555056605ERO1LBumls:C0004096BeFreePolymorphisms at the loci of nearby genes for NRG1 (rs4512342) and ERO1LB (rs10924993) were associated with neither the occurrence of nor exacerbations of asthma.0.0026384742008NRG1832750356TG
rs4512342183955503084NRG1umls:C0004096BeFreePolymorphisms at the loci of nearby genes for NRG1 (rs4512342) and ERO1LB (rs10924993) were associated with neither the occurrence of nor exacerbations of asthma.0.0026384742008NRG1832750356TG
rs4523108309126915TBXA2Rumls:C0004096BeFreeAssociation studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene.0.0216506752000TBXA2R193595796AG
rs452315805995450095PLFumls:C0004096BeFreeWe conducted an association study between known polymorphisms of IL-5 (T-746C) and TBXA2R (T924C) and asthma phenotype and the parameters of atopy and pulmonary function in atopic and nonatopic Korean children with asthma.0.013029212005TBXA2R193595796AG
rs4673659248242162066ERBB4umls:C0004096GWASCATGenome-wide interaction studies reveal sex-specific asthma risk alleles.0.122015ERBB42212325005AC
rs467564422424883130749CPOumls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012NA2206975608GC
rs4696480206857427097TLR2umls:C0004096BeFreeThe risk of having doctor-diagnosed asthma increased with increasing PM(2.5) levels in children with at least one copy of the TLR2 rs4696480 A allele (OR 2.0 (95% CI 1.2 to 3.1) for an interquartile range increase in exposure).0.0336476562010TLR24153685974TA
rs47524852242488355717WDR11umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012LOC10537851910120961461CT
rs475996611022011121256TMEM132Dumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000TMEM132D12129554313CA,G
rs4790522257152363565IL4umls:C0004096BeFreeThe results of logistic regression analysis indicated that TRPV1 expression level, IL-4 level, and rs4790522 site mutation were the main risk factors inducing bronchial asthma in children.0.354745832015TRPV1173566559AC
rs4794068205804426866TAC3umls:C0004096BeFreeA significant association with asthma was observed for two SNPs: rs2291855 in the TAC3 gene conferring asthma protection (Odds ratio [OR]: 0.46; 95% Confidence Interval [CI]: 0.22-0.97; P=0.038), and rs4794068 in the TAC4 gene associated with an increased risk for asthma (OR: 1.94; 95% CI: 1.06-3.54; P=0.03).0.0026384742010TAC4;FLJ455131749844979GA
rs479406820580442255061TAC4umls:C0004096BeFreeA significant association with asthma was observed for two SNPs: rs2291855 in the TAC3 gene conferring asthma protection (Odds ratio [OR]: 0.46; 95% Confidence Interval [CI]: 0.22-0.97; P=0.038), and rs4794068 in the TAC4 gene associated with an increased risk for asthma (OR: 1.94; 95% CI: 1.06-3.54; P=0.03).0.0026384742010TAC4;FLJ455131749844979GA
rs479482022561531101928947LOC101928947umls:C0004096GWASCATGenome-wide association study to identify genetic determinants of severe asthma.0.122012LRRC3C1739933091AG
rs479539722271045124626ZPBP2umls:C0004096BeFreeWe found that a single nucleotide polymorphism rs4795397 influences the activity of ZPBP2 promoter in vitro in an allele-dependent fashion, and also leads to nucleosome repositioning on the asthma-associated allele.0.0037242412012ZPBP21739867492AG
rs4802131102201126011TENM4umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000LOC1019289891182093529AG
rs48156172015924257506MAVSumls:C0004096GAD[This GWAS confirmed the important role of T(H)2 cytokine and antigen presentation genes in asthma at a genome-wide level and the importance of additional investigation of these 2 regions to delineate their structural complexity and biologic function in th]0.0023670322010MAVS203846662CT
rs482241022424883150244ZDHHC8P1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012NA2223423078AG
rs4831760224248837991TUSC3umls:C0004096GAD[The top ranking signal, TUSC3, which is associated with FEV(1)/FVC ratio decrease in asthmatic participants (PA = 5.3 A 10(-8)), did not replicate.]0.0026384742012TUSC3815675076TC
rs4833095243880137096TLR1umls:C0004096GWASCATGenome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.0.130368332013TLR1438798089TC
rs48457832180454954544CRCT1umls:C0004096GAD[Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.]0.0023670322011NA1152520083GA
rs4880166301486648SOD2umls:C0004096BeFreeTo investigate the association of the manganese-containing form of SOD (MnSOD) gene at amino acid position 16 (Val16Ala) and catalase gene in the promoter at A-21T and C-262T polymorphisms and asthma in a Hong Kong Chinese population.0.0058198312006SOD26159692840AG
rs4916008218273233716JAK1umls:C0004096BeFreeJAK-1 rs2780895 C-related genotype and allele but not JAK-1 rs10789166, rs4916008, rs2780885, rs17127114, and rs3806277 are associated with higher susceptibility to asthma.0.0026384742011JAK1164852824CT
rs4950928194214041116CHI3L1umls:C0004096BeFreeInterestingly, it has been reported that rs10399931 (-329 G/A) of CHI3LI contributes to the inter-individual plasma YKL-40 levels in patients with sarcoidosis, and that rs4950928 (-131 C/G) is a susceptibility polymorphism for asthma and a decline in lung function.0.016806992009CHI3L11203186754GC
rs4950928215308691116CHI3L1umls:C0004096BeFreeThe CHI3L1 rs4950928 polymorphism is associated with asthma-related hospital admissions in children and young adults.0.016806992011CHI3L11203186754GC
rs4950929110220111116CHI3L1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.016806992000NA1203190998GT
rs49519811022011376693RPS10P7umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NAV11201636988GA
rs4986790153565573586IL10umls:C0004096BeFreeDecreased LPS-induced IL-12(p70) and IL-10 responses were associated with the TLR4 (Asp299Gly) polymorphism and independently with asthma, especially atopic asthma.0.1537102272004TLR49117713024AG
rs4986790207114707099TLR4umls:C0004096BeFreeDetermination of the TLR4 Asp299Gly/Thr399Ile haplotype is of no clinical benefit in predicting the nature or intensity of cytokine production in children whether currently healthy or among specific at-risk groups characterized by prior infantile broncholitis or current asthma.0.0579989362010TLR49117713024AG
rs4986790255301387099TLR4umls:C0004096BeFreeWherease some previous studies indicated TLRs and their polymorphisms might have some role in asthma incidence and features, our data demonstrated that TLR2 Arg753Gln and TLR4 Asp299Gly gene variants were not risk factors for asthma or its features in Iranian patients.0.0579989362014TLR49117713024AG
rs4986790253310707099TLR4umls:C0004096BeFreeRole of TLR4 C>1196T (Thr399Ile) and TLR4 A>896G (Asp299Gly) polymorphisms in a North Indian population with asthma: a case-control study.0.0579989362014TLR49117713024AG
rs4986790255301387097TLR2umls:C0004096BeFreeWherease some previous studies indicated TLRs and their polymorphisms might have some role in asthma incidence and features, our data demonstrated that TLR2 Arg753Gln and TLR4 Asp299Gly gene variants were not risk factors for asthma or its features in Iranian patients.0.0336476562014TLR49117713024AG
rs4986790235743987099TLR4umls:C0004096BeFreeAssociation between the TLR4 +896A>G (Asp299Gly) polymorphism and asthma: a systematic review and meta-analysis.0.0579989362012TLR49117713024AG
rs4986791253310707099TLR4umls:C0004096BeFreeRole of TLR4 C>1196T (Thr399Ile) and TLR4 A>896G (Asp299Gly) polymorphisms in a North Indian population with asthma: a case-control study.0.0579989362014TLR49117713324CT
rs4986791207114707099TLR4umls:C0004096BeFreeDetermination of the TLR4 Asp299Gly/Thr399Ile haplotype is of no clinical benefit in predicting the nature or intensity of cytokine production in children whether currently healthy or among specific at-risk groups characterized by prior infantile broncholitis or current asthma.0.0579989362010TLR49117713324CT
rs502419213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011MS4A21160098702GA
rs502419213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011MS4A21160098702GA
rs502581213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011MS4A21160092705GT
rs502581213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011MS4A21160092705GT
rs504560NA10911UTS2umls:C0004096GADNA0.082638474NAUTS217866482AG
rs545854110220118658TNKSumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000LOC105379235810002570GC
rs5498166252133383ICAM1umls:C0004096BeFreeICAM1 amino-acid variant K469E is associated with paediatric bronchial asthma and elevated sICAM1 levels.0.2180744422006ICAM1;ICAM4;LOC1053722721910285007AG
rs549908182501353606IL18umls:C0004096BeFreeAn IL-18 genetic A/C polymorphism at coding position 105 (rs549908) has been linked with asthma and rheumatoid arthritis.0.036076822008IL1811112150193TA,G
rs549908192884493606IL18umls:C0004096BeFreeAn IL-18 genetic A/C polymorphism at coding position 105 (rs549908) has been linked with asthma, rheumatoid, and systemic lupus erythematosus.0.036076822009IL1811112150193TA,G
rs549908129117843606IL18umls:C0004096BeFreeAssociation between interleukin-18 gene polymorphism 105A/C and asthma.0.036076822003IL1811112150193TA,G
rs556917213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011MS4A21160091239AT
rs556917213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011MS4A21160091239AT
rs568404215137523593IL12Bumls:C0004096BeFreeThese results suggest that the SNPs in IL-12A rs568404 and IL-12B rs3212227 may individually and jointly contribute to the risk of asthma in a Chinese population.0.1542004712011NA10129233875CG
rs569108225332352206MS4A2umls:C0004096BeFreeTo investigate whether the single-nucleotide polymorphisms (SNPs) Ile75Val and Gln576Arg in the IL4RA gene, -33C>T in the IL4 gene, and Gly237Glu in the FCER1B gene contribute to the development and severity of atopic bronchial asthma in Russian patients from Moscow.0.0552223852012MS4A21160095631AG
rs5743618244458347096TLR1umls:C0004096BeFreeIn this study, we demonstrated that TLR1 rs5743618 was associated with asthma and atopic eczema during the first 6 years of life after early bronchiolitis.0.130368332014TLR1438797027CA
rs5743708255301387099TLR4umls:C0004096BeFreeWherease some previous studies indicated TLRs and their polymorphisms might have some role in asthma incidence and features, our data demonstrated that TLR2 Arg753Gln and TLR4 Asp299Gly gene variants were not risk factors for asthma or its features in Iranian patients.0.0579989362014TLR24153705165GA
rs5743708255301387097TLR2umls:C0004096BeFreeWherease some previous studies indicated TLRs and their polymorphisms might have some role in asthma incidence and features, our data demonstrated that TLR2 Arg753Gln and TLR4 Asp299Gly gene variants were not risk factors for asthma or its features in Iranian patients.0.0336476562014TLR24153705165GA
rs57438361616444054106TLR9umls:C0004096BeFreeRecently, a possible association of TLR9 polymorphism C-1237T with asthma has been reported.0.0199124032005TLR9352226766AG
rs57442922206927055829VIMPumls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.0002714422011IL1811112143413TC
rs5744292220692703606IL18umls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.036076822011IL1811112143413TC
rs5744562206927055829VIMPumls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.0002714422011LRP1B2140644133AT
rs574456220692703606IL18umls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.036076822011LRP1B2140644133AT
rs574700213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011MS4A21160088010CT
rs574700213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011MS4A21160088010CT
rs59317557206246511950EGFumls:C0004096BeFreeConsistent with predicted in silico functionality, alleles of the promoter SNPs rs2038366 (-1557G/T) and rs59317557 (-532C/G) influenced the activity of a luciferase S1PR1 reporter vector in transfected endothelial cells exposed to growth factors (epidermal growth factor, platelet-derived growth factor, and vascular endothelial growth factor) known to be increased in asthmatic airways.0.0010857672010S1PR1;LOC1019283701101236367CG
rs59317557206246517422VEGFAumls:C0004096BeFreeConsistent with predicted in silico functionality, alleles of the promoter SNPs rs2038366 (-1557G/T) and rs59317557 (-532C/G) influenced the activity of a luciferase S1PR1 reporter vector in transfected endothelial cells exposed to growth factors (epidermal growth factor, platelet-derived growth factor, and vascular endothelial growth factor) known to be increased in asthmatic airways.0.1479520892010S1PR1;LOC1019283701101236367CG
rs59569785248761738477GPR65umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0002714422015SOX51223618801CT
rs595697852487617364478CSMD1umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0026384742015SOX51223618801CT
rs59569785248761736660SOX5umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0002714422015SOX51223618801CT
rs6052761199100285621PRNPumls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.0050055062010NA204676371TC
rs605276119910028147ADRA1Bumls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.0050055062010NA204676371TC
rs60527611991002857628DPP10umls:C0004096BeFreeA meta-analysis combining these 2 African-ancestry populations yielded 3 SNPs with a combined P value of less than 10(-5) in genes of potential biologic relevance to asthma and allergic disease: rs10515807, mapping to the alpha-1B-adrenergic receptor (ADRA1B) gene on chromosome 5q33 (3.57 x 10(-6)); rs6052761, mapping to the prion-related protein (PRNP) gene on chromosome 20pter-p12 (2.27 x 10(-6)); and rs1435879, mapping to the dipeptidyl peptidase 10 (DPP10) gene on chromosome 2q12.3-q14.2.0.1116616862010NA204676371TC
rs60703462242488356937PMEPA1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012NA2058088218TC
rs618167612206927055829VIMPumls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.0002714422011FLG;FLG-AS11152313385GA,T
rs61816761220692703606IL18umls:C0004096BeFreeWe genotyped single nucleotide polymorphisms (SNPs): -105/rs28665122 in SELS or SEPS1 (selenoprotein), three single nucleotide polymorphisms in IL18 (-105/rs360717, +183/rs5744292 and +1467/rs574456) and R501X/rs61816761 in FLG, the major locus associated with atopic dermatitis and predisposing to asthma, in a minimum of 6743 T1D cases and 7864 controls.0.036076822011FLG;FLG-AS11152313385GA,T
rs61816761173018312312FLGumls:C0004096BeFreeMutations in FLG/(R501X and 2282del4) are reported to be strongly associated with AD and to influence asthma accompanying AD.0.0611664812007FLG;FLG-AS11152313385GA,T
rs61816761214264112312FLGumls:C0004096BeFreeIn the Polish patients with AD, the prevalence of FLG mutations was higher in patients with AD than in the controls and 2282del4 FLG mutation was more frequent than R501X, and it was associated with a 6-fold higher risk for AD development (P < 0.001; OR: 5.76), moderate or severe disease course, early onset of asthma and palmar hyperlinearity.0.0611664812011FLG;FLG-AS11152313385GA,T
rs6195224697832908NR3C1umls:C0004096BeFreeThe N363S and I559N single nucleotide polymorphisms of the h-GR/NR3C1 gene in patients with bronchial asthma.0.1036789132012NANANANANA
rs620263762438801323274CLEC16Aumls:C0004096GWASCATAt genome-wide significance, we identified 11 independent variants associated with the risk of having asthma with hay fever, including 2 associations reaching this level of significance with allergic disease for the first time: ZBTB10 (rs7009110; odds ratio [OR], 1.14; P = 4 × 10(-9)) and CLEC16A (rs62026376; OR, 1.17; P = 1 × 10(-8)).0.122013CLEC16A1611134855CT
rs6478317242437407099TLR4umls:C0004096BeFreeThe TLR4 single-nucleotide polymorphisms rs1927911, rs10759931, and rs6478317 modified the association of particulate matter and nitrogen dioxide with asthma.0.0579989362014NANANANANA
rs65035252115087894103ORMDL3umls:C0004096GAD[Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.]0.1723409262011LRRC3C1739938921GC
rs650352521150878101928947LOC101928947umls:C0004096GWASCATAssociation between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.0.122011LRRC3C1739938921GC
rs6574978248761736660SOX5umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0002714422015GPR651488011069CT
rs6574978248761738477GPR65umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0002714422015GPR651488011069CT
rs65749782487617364478CSMD1umls:C0004096BeFreeThe non-Hispanic white GWAS identified single nucleotide polymorphisms in the genes CSMD1 (rs11779254, p=1.57 × 10(-6)) and SOX5 (rs59569785, p=1.61 × 10(-6)) and the meta-analysis identified single nucleotide polymorphisms in the gene GPR65 (rs6574978, p=1.18 × 10(-7)) associated with COPD and asthma overlap.0.0026384742015GPR651488011069CT
rs6591255183351116927HNF1Aumls:C0004096BeFreeThe Ile105Val allele and a SNP in the upstream promoter region (SNP1: rs6591255, putative transcription factor 1 binding site) were associated with asthma and wheezing outcomes, an association observed in two cohorts of the CHS recruited in different years.0.0002714422008GSTP11167582077TA
rs6591255183351116625SNRNP70umls:C0004096BeFreeThe Ile105Val allele and a SNP in the upstream promoter region (SNP1: rs6591255, putative transcription factor 1 binding site) were associated with asthma and wheezing outcomes, an association observed in two cohorts of the CHS recruited in different years.0.0005428842008GSTP11167582077TA
rs6591256213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011GSTP11167582428AG
rs6591256213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011GSTP11167582428AG
rs662195750275444PON1umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0029099162009PON1795308134TC
rs6621957502754578UGT1A6umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0026384742009PON1795308134TC
rs662195750271545CYP1B1umls:C0004096BeFreeWe found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.0.0026384742009PON1795308134TC
rs6691378110220111116CHI3L1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.016806992000CHI3L11203187994GA
rs6755028256437475554PRH1umls:C0004096BeFreeFive SNPs of protein C gene (PROC) on 2q14 were associated with asthma, with rs6755028 being the most significant SNP.0.0002714422015LOC1053736082127437866GA
rs6780211102201126011TENM4umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000LOC1019289891182043646CT
rs6790467NA5021OXTRumls:C0004096GADNA0.002638474NAOXTR38784337AG
rs68273571102201153834FGFRL1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000RNF21241065414AC
rs68399311102201153834FGFRL1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000RNF21241059384TC
rs68715362424153710111RAD50umls:C0004096GWASCATFour of these, GSDMB, IL33, RAD50 and IL1RL1, were previously reported as asthma susceptibility loci, but the effect sizes for these loci in our cohort were considerably larger than in the previous genome-wide association studies of asthma.0.2463627152013RAD50;LOC1019277615132634182TC
rs6884431224248831501CTNND2umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012CTNND2511111659AG
rs68849051102201150834TAS2R1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000NA510148309CT
rs696733025848009222256CDHR3umls:C0004096BeFreeOur findings identify that the asthma susceptibility gene product CDHR3 mediates RV-C entry into host cells, and suggest that rs6967330 mutation could be a risk factor for RV-C wheezing illnesses.0.2402714422015CDHR37106018005GA
rs696733024241537222256CDHR3umls:C0004096GWASCATA genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.0.2402714422013CDHR37106018005GA
rs698275124388013286046XKR6umls:C0004096GWASCATGenome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.0.122013XKR6810955964CG
rs700629022424883286ANK1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012ANK1841757620GA
rs7006742224248838989TRPA1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.1223670322012NA872324575CT
rs70279302242488323189KANK1umls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012KANK19565917TC
rs70488781102201123287AGTPBP1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000LOC102724057985783990CT
rs7124442224687302534FYNumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0056342662012BDNF;BDNF-AS1127655494CT
rs7124442224687304804NGFRumls:C0004096BeFreeAnalysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).0.0026384742012BDNF;BDNF-AS1127655494CT
rs7130588219078641258CNGB1umls:C0004096BeFreeTwo loci were confirmed to associate with asthma risk in the replication cohorts and reached genome-wide significance in the combined analysis of all available studies (n=57,800): rs4129267 (OR 1·09, combined p=2·4×10(-8)) in the interleukin-6 receptor (IL6R) gene and rs7130588 (OR 1·09, p=1·8×10(-8)) on chromosome 11q13.5 near the leucine-rich repeat containing 32 gene (LRRC32, also known as GARP).0.0002714422011NA1176559639AG
rs71305882190786456946C11orf30umls:C0004096GAD[The IL6R association further supports the hypothesis that cytokine signalling dysregulation affects asthma risk, and raises the possibility that an IL6R antagonist (tocilizumab) may be effective to treat the disease, perhaps in a genotype-dependent manner]0.0026384742011NA1176559639AG
rs721293824388013284110GSDMAumls:C0004096GWASCATA variant near LRRC32 was a stronger risk factor for hay fever than for asthma, whereas the reverse was observed for variants in/near GSDMA and TSLP.0.1237242412013GSDMA1739966427GA,T
rs72129382262659222806IKZF3umls:C0004096BeFreeSixteen SNPs were significantly associated with asthma after multiple testing correction (P ≤ .01), of which 5 (rs2290400, rs8079416, rs3894194, rs7212938, and rs3859192) were strongly associated (FDR P ≤ .0002), and one was novel (IKZF3-rs1453559).0.1210857672012GSDMA1739966427GA,T
rs72163891913392155876GSDMBumls:C0004096BeFreeWe genotyped rs4378650 in ORMDL3 and rs7216389 in GSDML in 615 nuclear families consisting of asthmatic children aged 4-17 years and their parents.0.2632793262009GSDMB1739913696CT
rs72163891761149655876GSDMBumls:C0004096GAD[Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.]0.2632793262007GSDMB1739913696CT
rs72163891761149655876GSDMBumls:C0004096GWASCATGenetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.0.2632793262007GSDMB1739913696CT
rs72163892037218955876GSDMBumls:C0004096BeFreeThus, the contribution of rs7216389-T to the development of asthma is unlikely to operate only through an impact on the expression of ORMDL3 or GSDMB genes.0.2632793262010GSDMB1739913696CT
rs72163892037218994103ORMDL3umls:C0004096BeFreeThus, the contribution of rs7216389-T to the development of asthma is unlikely to operate only through an impact on the expression of ORMDL3 or GSDMB genes.0.1723409262010GSDMB1739913696CT
rs730012201284194056LTC4Sumls:C0004096BeFreeWe analyzed the effects of LTC4S -444 A/C, ALOX5 -176/-147, and ALOX5AP -169/-146 on asthma susceptibility by means of a case-control study with 193 ethnically matched, unrelated individuals.0.068648642009LTC4S5179793637AC
rs730012228848584056LTC4Sumls:C0004096BeFreeThe -444A/C polymorphism in the LTC4S gene and the risk of asthma: a meta-analysis.0.068648642012LTC4S5179793637AC
rs7302032110220113741KCNA5umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0026384742000LOC105369617125246207GA
rs733618192649731493CTLA4umls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.0381961542009CTLA42203866221TC
rs743119176439732730GCLMumls:C0004096BeFreeThe present study was designed to investigate an association of common -588C/T and -23G/T polymorphisms within glutamate cysteine ligase modifier subunit gene with susceptibility to bronchial asthma.0.0026384742007GCLM193909186CA
rs744910208605034088SMAD3umls:C0004096GWASCATWe observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).0.1229099162010SMAD31567154447GA
rs744910208605034088SMAD3umls:C0004096GAD[We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3A10(a9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7A10(a14)); rs1342326 on chromosome 9, flanking IL33 (P=9A10(a10)); rs744910 on chromosome 15 in SMAD3 (P=4A10(a9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1A10(a8)).]0.1229099162010SMAD31567154447GA
rs75216812438801310451VAV3umls:C0004096GWASCATGenome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.0.122013VAV31107779913GA
rs76043829243880137145TNS1umls:C0004096BeFreeSingle nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).0.1205428842013TNS12217812863GA
rs76043829243880137145TNS1umls:C0004096GWASCATSingle nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).0.1205428842013TNS12217812863GA
rs76043829243880133559IL2RAumls:C0004096BeFreeSingle nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).0.0890771342013TNS12217812863GA
rs763780243930793605IL17Aumls:C0004096BeFreeWe investigated the possible association among asthma and IL-17A -197G/A (rs2275913), IL-17F 7488A/G (rs763780) and IL-17F 7383A/G (rs2397084).0.1001501692014IL17F;LOC105375088652236941TC
rs76378016961709112744IL17Fumls:C0004096BeFreeGiven that asthma and COPD are complex diseases involving a number of genetic and environmental factors, the genetic impact of IL-17F H161R with regard to the development of chronic airway inflammation likely varies among individuals with different genetic backgrounds and environmental exposures.0.0058957762006IL17F;LOC105375088652236941TC
rs76378016630936112744IL17Fumls:C0004096BeFreeIL-17F sequence variant (His161Arg) is associated with protection against asthma and antagonizes wild-type IL-17F activity.0.0058957762006IL17F;LOC105375088652236941TC
rs76696221102201153834FGFRL1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000RNF21241064871TC
rs770389162017580354738FEVumls:C0004096BeFreeOur results suggest that NK2R G231E G>A and TBX21 H33Q C>G are genetic predictors of response to ICS, at least with respect to asthma control status and changes in FEV(1)%, in Korean patients with asthma.0.0211724662009TACR2;LOC1053783431069408971CT
rs770389162017580330009TBX21umls:C0004096BeFreePharmacogenetic study of the effects of NK2R G231E G>A and TBX21 H33Q C>G polymorphisms on asthma control with inhaled corticosteroid treatment.0.1504524852009TACR2;LOC1053783431069408971CT
rs77038916201758036865TACR2umls:C0004096BeFreePharmacogenetic study of the effects of NK2R G231E G>A and TBX21 H33Q C>G polymorphisms on asthma control with inhaled corticosteroid treatment.0.005548392009TACR2;LOC1053783431069408971CT
rs77370312191260411127KIF3Aumls:C0004096BeFreeThe association between KIF3A rs7737031 and asthma was validated in 3 independent populations, further substantiating the validity of our gene selection approach.0.1205428842011KIF3A5132710898CT
rs77417511102201164094SMOC2umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000LOC1053781456169040845CT
rs7922491219078645592PRKG1umls:C0004096GWASCATIdentification of IL6R and chromosome 11q13.5 as risk loci for asthma.0.1223670322011PRKG1;LOC1053783041051733713GA
rs7922491219078645592PRKG1umls:C0004096GAD[The IL6R association further supports the hypothesis that cytokine signalling dysregulation affects asthma risk, and raises the possibility that an IL6R antagonist (tocilizumab) may be effective to treat the disease, perhaps in a genotype-dependent manner]0.1223670322011PRKG1;LOC1053783041051733713GA
rs7975232196221397421VDRumls:C0004096BeFreeAlthough the susceptibility of VDR gene variants with asthma could not be confirmed for all SNPs tested in this study, the significant association obtained for rs7975232 provides evidence for a previously unknown report about the Chinese Han population and may raise the susceptibility of VDR to be a candidate gene for asthma.0.0177171242009VDR;LOC1053697491247845054CA
rs803010221828085729PTGDRumls:C0004096BeFreeNo association of PTGDR -441C/T polymorphism with asthma in a North Indian population.0.0310950582011PTGDR1452267374TC
rs803395711022011161835FSIP1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0050055062000FSIP11539746232TC
rs8049738110220119951HS3ST4umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000HS3ST41625958711TC
rs80794162262659222806IKZF3umls:C0004096BeFreeSixteen SNPs were significantly associated with asthma after multiple testing correction (P ≤ .01), of which 5 (rs2290400, rs8079416, rs3894194, rs7212938, and rs3859192) were strongly associated (FDR P ≤ .0002), and one was novel (IKZF3-rs1453559).0.1210857672012LRRC3C1739936460TC
rs820336220159494638MYLKumls:C0004096BeFreeWe studied the potential regulatory roles of two intronic MYLK SNPs (rs936170 and rs820336) previously associated with ALI and asthma.0.0173598052012MYLK;LOC1053691943123696934CT
rs82861822261696131566DCBLD2umls:C0004096BeFreeResults reveal significant association of rs828618 and DCBLD2_ht1 with nasal polyposis in the overall asthma patients group (P = 0.006, P(corr) = 0.05).0.0005428842012DCBLD2398822789GA
rs832147110220115317PKP1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000PKP11201300559CG
rs8811522067398454738FEVumls:C0004096BeFreeAmong the group of SAPPHIRE participants prospectively treated with ICSs for 6 weeks, rs881152 genotype was significantly associated with changes in self-reported asthma control but not FEV(1).0.0211724662010DUSP1;LOC1053777305172771552GA
rs907922440607322806IKZF3umls:C0004096BeFreeWe confirmed the strong allelic association between SNPs in the 17q21 region and asthma in Latinos (IKZF3, lowest P value: rs90792, odds ratio, 0.67; 95% CI, 0.61-0.75; P = 6 × 10(-13)) and replicated associations in several genes that had previously been associated with asthma in genome-wide association studies.0.1210857672013NANANANANA
rs909253188116224049LTAumls:C0004096BeFreeThe following study populations were genotyped for 4 polymorphisms within TNF-beta (rs909253) and TNF-alpha (rs1799964, rs1799724, rs1800629): 322 asthmatic children, 151 children with severe respiratory syncytial virus (RSV) bronchiolitis and 270 controls.0.049488432009LTA;LOC100287329631572536AG
rs9268516230284839173IL1RL1umls:C0004096BeFreeWe also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus.0.2670894442012NA632411712CT
rs9268516230284838809IL18R1umls:C0004096BeFreeWe also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus.0.1426367532012NA632411712CT
rs9272346231817883117HLA-DQA1umls:C0004096GWASCATHLA-DQA1 is the fourth member of the HLA family found to be associated with asthma, in addition to the previously identified HLA-DRA, HLA-DQB1 and HLA-DQA2.0.2553738362012HLA-DQA1632636595GA
rs9284132424153790865IL33umls:C0004096GWASCATFour of these, GSDMB, IL33, RAD50 and IL1RL1, were previously reported as asthma susceptibility loci, but the effect sizes for these loci in our cohort were considerably larger than in the previous genome-wide association studies of asthma.0.2552443522013IL3396213387GA
rs9319321191873322835GPR12umls:C0004096GAD[These findings suggested that multiple genetic polymorphisms of CTNNA3 may be determinants of susceptibility to TDI-induced asthma.]0.0047340642009NA1326841536AT
rs936170220159494638MYLKumls:C0004096BeFreeWe studied the potential regulatory roles of two intronic MYLK SNPs (rs936170 and rs820336) previously associated with ALI and asthma.0.0173598052012MYLK;LOC1053691943123703970GC
rs9378805240743333662IRF4umls:C0004096BeFreeThe IRF-4 variant rs9378805 was associated with recurrent bronchitis in the ISAAC population and replicated in the GWAS data set where further SNPs showed associations with recurrent bronchitis and asthma.0.0008143262013NA6417727AC
rs946263192649731116CHI3L1umls:C0004096GAD[We replicated asthma associations for a minority of candidate genes.]0.016806992009NA1203196253GA
rs946263110220111116CHI3L1umls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.016806992000NA1203196253GA
rs947895213203442950GSTP1umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.2239365422011GSTP11167586935CA
rs947895213203442206MS4A2umls:C0004096BeFreeChromosome 11 haplotype CTACGAGGCC (corresponding to MS4A2 rs574700, rs1441586, rs556917, rs502581, rs502419 and GSTP1 rs6591256, rs17593068, rs1695, rs1871042, rs947895) was associated with a nearly five-fold increase in the odds of asthma (Odds Ratio (OR) = 4.8, p = 0.007).0.0552223852011GSTP11167586935CA
rs9500927218045486046BRD2umls:C0004096GAD[Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.]0.0026384742011NA632993584GA
rs96357262362200522806IKZF3umls:C0004096BeFreeWe found 2 SNPs (1 novel rs9635726 in IKZF3) to be associated with asthma.0.1210857672013IKZF31739863888CT
rs9644708110220118658TNKSumls:C0004096GAD[A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.]0.0023670322000TNKS89743407TC
rs9807989225615318809IL18R1umls:C0004096GWASCATGenome-wide association study to identify genetic determinants of severe asthma.0.1426367532012IL18R12102354740TC
rs98235062382968625890ABI3BPumls:C0004096GWASCATRank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.0.122013ABI3BP3100757869CT
rs987870218145173115HLA-DPB1umls:C0004096GAD[Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.]0.2671852512011HLA-DPA1;HLA-DPB1633075103AG
rs987870218145173113HLA-DPA1umls:C0004096GAD[SNP rs987870, located between HLA-DPA1 and HLA-DPB1, was consistently associated with pediatric asthma in 3 independent populations (P(combined)a=a2.3A10(-10), odds ratio ORa=a1.40).]0.1226384742011HLA-DPA1;HLA-DPB1633075103AG
rs987870218145173115HLA-DPB1umls:C0004096GWASCATGenome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.0.2671852512011HLA-DPA1;HLA-DPB1633075103AG
rs987870218145173113HLA-DPA1umls:C0004096GWASCATSNP rs987870, located between HLA-DPA1 and HLA-DPB1, was consistently associated with pediatric asthma in 3 independent populations (P(combined) = 2.3×10(-10), odds ratio [OR] = 1.40).0.1226384742011HLA-DPA1;HLA-DPB1633075103AG
rs987870218145173113HLA-DPA1umls:C0004096BeFreeSNP rs987870, located between HLA-DPA1 and HLA-DPB1, was consistently associated with pediatric asthma in 3 independent populations (P(combined) = 2.3×10(-10), odds ratio [OR] = 1.40).0.1226384742011HLA-DPA1;HLA-DPB1633075103AG
rs98950982482421623108RAP1GAP2umls:C0004096GWASCATGenome-wide interaction studies reveal sex-specific asthma risk alleles.0.122015RAP1GAP2173035239TC
rs9979235224248835152PDE9Aumls:C0004096GAD[Genetic heterogeneity of lung function might be extensive. Our results suggest that genetic determinants of longitudinal and cross-sectional lung function differ and vary by asthma status.]0.0023670322012PDE9A;LOC1019282842142736659AG
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:1747)
CHR POS SNPID REF ALT ORI_SNPID PMID P_VALUE P_VALUE_TEXT OR/BETA CI95_TEXT GWAS_INITIAL_SAMPLE_SIZE SUB_POPULATION SUPER_POPULATION GWAS_TRAIT HPO_ID HPO_TERM DO_ID DO_TERM MESH_ID MESH_TERM EFO_ID EFO_TERM DOLITE_TERM RISK_ALLELE PUBLICATION_TYPE AA GENE_SYMBOL TYPE REFGENE
12526746rs3748816AGrs3748816211508783.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
14682104rs6668002TCrs6668002pha0031279.98E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
17425064rs1418489AGrs1418489238296862.52E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralACAMTA1
17926542rs504560AGrs504560pha0031279.16E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
111957639rs12724129CTrs12724129206989756.83E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
112419883rs148728975GArs148728975244060737.00E-07NA2.13[1.59-2.13]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
117394775rs2235927GArs2235927231817881.21E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
120015300rs16822732GArs16822732110220115.30E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars16822732-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
120018195rs3748748GArs3748748110220116.63E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3748748-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
120140036rs1317209GArs1317209219078642.00E-10NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
122698447rs7524102AGrs7524102217328293.00E-09NA1.28[1.17-1.41] 856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseasers7524102-GResearch Support, Non-U.S. Gov'tGNA
124881126rs6424099CTrs6424099206989756.00E-05AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
125303576rs10903122AGrs10903122211508782.00E-10NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
125303576rs10903122AGrs10903122219078642.00E-10NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
129594563rs7550930TCrs7550930217900088.03E-06Atopic dermatitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCPTPRU
134902910rs4653032CArs4653032231817881.82E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
141240519rs823673CTrs823673235413243.94E-05FEV1/FVC ratio0.19[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars823673-AResearch Support, N.I.H., Extramural
142202714rs710235TCrs710235209207761.78E-05Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
142213076rs4284254GArs4284254209207761.98E-06Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
142250456rs7517484TCrs7517484209207763.16E-06Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
142326017rs655198AGrs655198201592428.87E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
142345723rs11210537GArs11210537239672696.39E-05NA1.33[1.33-2.33]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars11210537-AResearch Support, Non-U.S. Gov'tGHIVEP3
142345723rs11210537GArs11210537239672696.99E-05NA1.3[1.30-2.17]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars11210537-AResearch Support, Non-U.S. Gov'tGHIVEP3
142350837rs2993120ACrs2993120239672695.17E-05NA1.33[1.33-2.38]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2993120-AResearch Support, Non-U.S. Gov'tAHIVEP3
142350837rs2993120ACrs2993120239672696.00E-05NA1.3[1.30-2.17]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2993120-AResearch Support, Non-U.S. Gov'tAHIVEP3
142353344rs12024772AGrs12024772239672694.55E-05NA1.35[1.35-2.38]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12024772-GResearch Support, Non-U.S. Gov'tAHIVEP3
142353344rs12024772AGrs12024772239672695.73E-05NA1.3[1.30-2.17]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12024772-GResearch Support, Non-U.S. Gov'tAHIVEP3
142371447rs6600391CTrs6600391238296862.73E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCHIVEP3
143357369rs12070405GTrs12070405238296865.93E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
147118168rs2289447CTrs2289447216968132.20E-08Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
147118189rs620431GTrs620431216968134.00E-04Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
147118918rs1150068AGrs1150068216968132.00E-04Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
147142538rs1048380GArs1048380216968131.00E-04Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
147148044rs1150064TArs1150064216968138.79E-05Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
147167238rs1440486CTrs1440486216968132.26E-05Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
147176818rs2218189TCrs2218189216968131.00E-04Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
147187908rs6670495TArs6670495216968137.93E-06Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
147220059rs6662321CTrs6662321216968139.00E-04Asthma (childhood asthma)NANA112 European ancestry children cases; 165 European ancestry children controlsEuropean(277)ALL(277)EUR(277)ALL(277)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMulticenter StudyClinical TrialResearch Support, N.I.H., Extramural
149196060rs6661901GArs6661901227920825.30E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
155453391rs13374752AGrs13374752238296866.11E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGTMEM61
157177388rs1342382TArs1342382184015940.00007NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
158231158rs1886140AGrs1886140237067090.0000065NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tADAB1
161688282rs7552300CTrs7552300238296865.82E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNFIA
163674914rs1328589TGrs1328589201592426.50E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
163713524rs10493343CArs10493343201592421.37E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
167702526rs11465804TGrs11465804211508787.00E-63NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
178749908rs6424762CArs6424762225615311.70E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
186371149rs1858556TCrs1858556184015940.00007NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
186377028rs10493777CTrs10493777184015940.00007NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
192099741rs1887054GArs1887054231817886.93E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
194089708rs236313ACrs236313231817882.24E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1105220965rs12725071CTrs12725071206989754.52E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1107837159rs4604720GArs4604720231817883.15E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA,G
1109156284rs943806CTrs943806238296861.62E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralAFAM102B
1114377568rs2476601AGrs2476601211508781.00E-08NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG,C
1115739084rs12035380CTrs12035380225027970.000706NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1115782068rs1777719AGrs1777719225027970.000336NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1117129711rs17036023AGrs17036023238296865.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralAIGSF3
1119102839rs17185776TCrs17185776217900085.95E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTNA
1151501737rs6678068TCrs6678068pha0031286.22E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACCGNintron
1152476743rs499913TArs499913230408850.00000072NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1152480233rs1885531TGrs1885531230408850.0000037NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1152492559rs4845783GArs4845783218045496.00E-06NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1152496012rs1538084ACrs1538084218045495.01E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1152529622rs6587688TCrs6587688218045491.47E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1154426264rs4129267CTrs4129267219078642.00E-08NA1.09[1.06-1.12] 12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars4129267-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1154633513rs1876304GTrs1876304pha0031288.50E-06phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
1154652572rs6698385AGrs6698385pha0031282.83E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
1158932555rs1101999CTrs1101999218045494.00E-09NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1159685136rs3093059AGrs3093059219078644.00E-21NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1160852046rs2274910TCrs2274910211508781.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1165497692rs285461TCrs285461235413249.56E-05ppFEV10.22[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars285461-TResearch Support, N.I.H., Extramural
1172789765rs11810332AGrs11810332pha0031281.58E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
1172795995rs10912477ACrs10912477pha0031281.57E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
1172862234rs9286879AGrs9286879211508782.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1173353159rs6701588GArs6701588225615314.21E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1174219398rs16846809AGrs16846809206989756.70E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1174440683rs10489261CTrs10489261206989751.10E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1174737457rs6692753GTrs6692753206989754.20E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1176423140rs4471226CTrs4471226243154512.96E-04(EA)0.09[0.04-0.14] unit decrease5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4471226-CMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1176423140rs4471226CTrs4471226243154513.00E-06NA0.1[0.056-0.138] unit decrease5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
1180645441rs7527074CTrs7527074238296869.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTXPR1
1182959364rs10911180CArs10911180239672691.40E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
1183004076rs10911203GArs10911203239672696.53E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGLAMC1
1183143422rs17479287GArs17479287239672691.10E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
1184442054rs4651208TCrs4651208235413246.34E-05ppFEV10.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4651208-TResearch Support, N.I.H., Extramural
1186550535rs4140432TGrs4140432239672697.28E-05NA1.29[1.29-2.17]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4140432-GResearch Support, Non-U.S. Gov'tTNA
1186598610rs10489397CArs10489397239672693.31E-05NA1.32[1.32-2.22]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10489397-AResearch Support, Non-U.S. Gov'tCNA
1186599524rs2383513TCrs2383513239672691.73E-05NA1.35[1.35-2.27]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2383513-CResearch Support, Non-U.S. Gov'tCNA
1188275062rs12136061CTrs12136061239672691.10E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
1192536813rs2816316CArs2816316211508782.00E-17NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1193589444rs1339307AGrs1339307217900087.00E-06Lung function, forced expiratory volume in 1 second (FEV1)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
1194550938rs3001156CArs3001156201592429.46E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1195170004rs687523AGrs687523217900085.53E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTNA
1197325908rs2786098TA,C,Grs2786098200323182.00E-13NA1.43NA793 European ancestry child cases; 1,988 European ancestry child controlsEuropean(2781)ALL(2781)EUR(2781)ALL(2781)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, Non-U.S. Gov'tResearch Support, N.I.H., Intramural
1197508901rs4915551GArs4915551235170422.80E-05ChildrenNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
1197529218rs2111931CTrs2111931235170422.90E-04ChildrenNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
1197733055rs1775456GArs1775456219078643.00E-07NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1197733055rs1775456GArs1775456235170425.20E-04ChildrenNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
1197738327rs1924518AGrs1924518235170422.90E-04ChildrenNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
1197740690rs1775444TCrs1775444235170425.80E-04ChildrenNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
1198876258rs1322916TCrs1322916231817881.35E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1200892137rs296547TCrs296547211508784.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1200935866rs11584383TCrs11584383211508781.00E-11NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1201269687rs832147CGrs832147110220116.81E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars832147-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1201423658rs16848610ACrs16848610110220111.93E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars16848610-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1201606116rs495198GArs495198110220112.19E-06phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars495198-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1202052013rs4436440TArs4436440110220115.16E-07phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars4436440-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1202055938rs10800812AGrs10800812110220111.62E-08phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10800812-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1202390914rs12734001CTrs12734001217900082.79E-07Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCPPP1R12B
1202464760rs3817222CTrs3817222217900082.18E-07Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCPPP1R12B
1202469723rs12734338TCrs12734338206989751.70E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1202476648rs12743401TCrs12743401206989754.20E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1203133652rs16851020GTrs16851020110220114.14E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars16851020-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1203155882rs4950928GCrs4950928184037591.00E-13NA0.3[NA] ng/ml decrease632 individualsNOPOP(632)ALL(632)NOPOP(632)ALL(632)YKL-40 levelsHPOID:0002099AsthmaDOID:2841DOID:1324asthmalung cancerD015415Biological MarkersEFOID:0004869ykl40 measurementAsthmaLung cancerrs4950928-G
1203157122rs6691378GArs6691378110220113.76E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars6691378-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1203160126rs4950929GTrs4950929110220111.32E-12phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars4950929-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1203165381rs946263GArs946263110220119.74E-13phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars946263-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1203168474rs2153101ATrs2153101110220119.74E-13phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2153101-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1205084120rs7515178GArs7515178239672698.51E-05NA1.7[1.70-4.80]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7515178-AResearch Support, Non-U.S. Gov'tARBBP5
1205257338rs1562866TCrs1562866206989757.30E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1207494416rs2564978TCrs2564978210722015.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCCD55
1209932121rs10489341CTrs10489341206989759.20E-05AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1217435636rs4146799GArs4146799217900088.05E-06Bronchial asthma, age of onset after age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
1217453219rs4846406GArs4846406217900088.05E-06Bronchial asthma, age of onset after age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
1217461144rs4846411CArs4846411217900088.05E-06Bronchial asthma, age of onset after age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
1218105019rs10495085CTrs10495085239672691.40E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
1221617076rs12032381ACrs12032381209715836.00E-06NA6.22[2.37-16.31] 37 European ancestry cases; 34 European ancestry controlsEuropean(71)ALL(71)EUR(71)ALL(71)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseasers12032381-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1221969368rs10495179CTrs10495179110220118.26E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10495179-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1221979367rs11118864CTrs11118864110220112.88E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars11118864-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1225011642rs2662928AGrs2662928110220118.79E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2662928-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1225018101rs1892121AGrs1892121110220116.78E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1892121-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1225624016rs4653637GArs4653637206989752.90E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1225824028rs2840967CTrs2840967206989753.70E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1225974531rs4653433AGrs4653433218045495.44E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1229291651rs9287024TGrs9287024110220114.14E-06phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars9287024-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1229666990rs446924CTrs446924239672694.32E-05NA1.61[1.61-4.55]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars446924-CResearch Support, Non-U.S. Gov'tCABCB10
1232827343rs4308924TCrs4308924110220117.97E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars4308924-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1235760817rs10926189CTrs10926189239672695.20E-05NA1.43[1.43-2.81]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10926189-TResearch Support, Non-U.S. Gov'tCGNG4
1236459785rs10924993TGrs10924993176114967.00E-07NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1237326348rs10754593GCrs10754593213592103.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tG
1237390732rs6683160ACrs6683160239672693.31E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tARYR2
1240644644rs12734326CTrs12734326230408850.0000071NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1240693711rs3748540CTrs3748540235413247.88E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars3748540-AResearch Support, N.I.H., Extramural
1241724922rs3753214TCrs3753214206989752.20E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1244511176rs4658627GArs4658627225604796.00E-06NA0.13[NA] unit decrease573 European ancestry childrenEuropean(573)ALL(573)EUR(573)ALL(573)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmars4658627-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1246372880rs10802346GCrs10802346243154517.17E-05(EA)0.08[0.04-0.12] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10802346-CMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1246372880rs10802346GCrs10802346243154518.00E-06NA0.08[0.043-0.109] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
23703041rs17445240AGrs17445240247923825.01E-07NA0.36[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
23704830rs13418767GTrs13418767247923822.77E-06NA0.34[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
23707423rs6754459CTrs6754459247923825.73E-07NA0.36[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTALLC
23723026rs11123610GArs11123610247923824.00E-07NA0.37[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGALLC
212181825rs11690527CTrs11690527226949300.000000899NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
212366908rs1453488CTrs1453488235413244.35E-05ppFEV10.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1453488-TResearch Support, N.I.H., Extramural
212369870rs4669834AGrs4669834235413245.13E-05ppFEV10.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4669834-AResearch Support, N.I.H., Extramural
217530815rs7602088AGrs7602088217900083.67E-06Allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractANA
220819316rs896733GTrs896733225615312.87E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
229725676rs11684392CTrs11684392217900083.00E-06Lung function, forced expiratory volume in 1 second (FEV1)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCALK
230480865rs13386455AGrs13386455pha0031286.36E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAALBHUTR-3
231243964rs17010574GCrs17010574238296863.67E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGGALNT14
231246546rs10197865CTrs10197865239672695.48E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTGALNT14
231249974rs7608731TCrs7608731239672698.15E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCGALNT14
231254348rs1862968CTrs1862968239672691.10E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tAGALNT14
231263433rs9308914CArs9308914239672691.00E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCGALNT14
235764414rs1439706TCrs1439706238296865.75E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
236631779rs3770924AGrs3770924239672691.30E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTCRIM1
236675530rs848512AGrs848512239672691.00E-06NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTCRIM1
236680848rs711254AGrs711254239672696.73E-06NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTCRIM1
240115696rs6721181CTrs6721181238296866.00E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
242028633rs10211025AGrs10211025244060739.70E-07NA1.37[1.20-1.37]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
242035110rs12328045ACrs12328045244060734.60E-06NA1.33[1.18-1.50]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
244512971rs3768919GA,C,Trs3768919231817882.29E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
244517662rs6706053TCrs6706053231817881.07E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
247948101rs797700CTrs797700226949300.0000817NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
254797798rs6734445CTrs6734445206989758.30E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
254818895rs7584223TCrs7584223206989756.40E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
254859403rs6545435CTrs6545435206989751.60E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
257091538rs2111724CTrs2111724231817887.38E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
259749401rs2110565AGrs2110565235413246.15E-05ppFVC0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2110565-TResearch Support, N.I.H., Extramural
259794609rs2539669AGrs2539669217900085.52E-06Bronchial asthma, age of onset after age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
261186829rs13003464AGrs13003464211508784.00E-13NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
262805224rs17025954AGrs17025954237067090.0000074NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
265283174rs2302647GArs2302647210722012.00E-04Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
265283174rs2302647GArs2302647210722015.00E-05Lung function, forced expiratory volume in 1 second (FEV1) decline by aspirin provocationNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
265296280rs2252867TCrs2252867210722017.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGCEP68
265296280rs2252867TCrs2252867210722019.00E-05Lung function, forced expiratory volume in 1 second (FEV1) decline by aspirin provocationNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGCEP68
265296798rs7572857GArs7572857210722013.00E-05Lung function, forced expiratory volume in 1 second (FEV1) decline by aspirin provocationNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGCEP68
265296798rs7572857GArs7572857210722016.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGCEP68
265298282rs2723087TArs2723087210722014.00E-04Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tACEP68
265298282rs2723087TArs2723087210722019.00E-05Lung function, forced expiratory volume in 1 second (FEV1) decline by aspirin provocationNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tACEP68
265306905rs6741255CTrs6741255210722011.00E-04Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCCEP68
265306905rs6741255CTrs6741255210722015.00E-05Lung function, forced expiratory volume in 1 second (FEV1) decline by aspirin provocationNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCCEP68
266725867rs12619205GArs12619205231802724.64E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tAMEIS1
266725940rs13023583TCrs13023583231802726.84E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTMEIS1
268598955rs17035378TCrs17035378211508788.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
269245228rs6716266TGrs6716266176114961.00E-08NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
269328218rs1106518GArs1106518231817885.67E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2102741718rs12619383AGrs12619383226949300.0000255NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2102769786rs949963CTrs949963218045498.32E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102771341rs871657CTrs871657218045497.08E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102844020rs3755285TCrs3755285226949300.00000513NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2102844020rs3755285TCrs3755285pha0031271.42E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAAIL1RL2intron
2102879464rs10189629CArs10189629218045492.48E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102883975rs11692065CTrs11692065218045491.56E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102887128rs11674302TCrs11674302208605031.69E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2102887128rs11674302TCrs11674302218045497.75E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102953617rs3771180GTrs3771180218045492.00E-15NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102954653rs13431828CTrs13431828199100302.00E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
2102954653rs13431828CTrs13431828208605031.26E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2102954653rs13431828CTrs13431828218045492.77E-08NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102955056rs13408569GCrs13408569218045493.79E-08NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102955082rs13408661GArs13408661218045493.78E-08NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102955082rs13408661GArs13408661230284831.00E-09NA1.23[1.15-1.31] 1,716 European ancestry cases; 16,888 European ancestry controlsEuropean(18604)ALL(18604)EUR(18604)ALL(18604)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars13408661-GResearch Support, Non-U.S. Gov'tResearch Support, N.I.H., IntramuralG
2102955468rs1041973CArs1041973199100303.50E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
2102957348rs10173081CTrs10173081218045491.42E-08NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102966549rs10197862AGrs10197862218045496.31E-08NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102968212rs10204137AGrs10204137208605031.40E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2102968356rs10192157CTrs10192157208605032.11E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2102968362rs10206753TCrs10206753208605031.54E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2102971200rs9807989TCrs9807989225615316.00E-08NA1.33[1.20-1.47] 933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2102978459rs3755276CTrs3755276218045498.10E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102984624rs1362348CGrs1362348218045498.46E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2102986222rs3771166GArs3771166208605033.00E-09NA1.15[1.10-1.20] 10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3771166-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2102986222rs3771166GArs3771166219078643.40E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2102986222rs3771166GArs3771166225615313.40E-09NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2102986222rs3771166GArs3771166242415372.80E-04NA1.22[1.10-1.36]1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3771166-GNATIL18R1
2102990648rs17027029GCrs17027029236662770.0000997NANANA745 African American cases; 3238 African American controlsAfrican American(3983)ALL(3983)AFR(3983)ALL(3983)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2103009537rs4851004CTrs4851004208605031.41E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2103011237rs2287033TCrs2287033208605031.24E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2103015687rs1420094CTrs1420094208605031.18E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2103042712rs3755266GArs3755266208605038.71E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2103049074rs2310300AGrs2310300208605038.92E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2103070568rs917997TCrs917997211508781.00E-15NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2106160606rs6726692AGrs6726692231817881.12E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2108603967rs333236GArs333236225615316.47E-06NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2108938735rs12477830AGrs12477830217900087.00E-06Lung function, forced vital capacity (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractANA
2113457049rs10211073AGrs10211073227920822.50E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2115492887rs1435879AGrs1435879199100283.05E-06AsthmaNANA464 African American cases; 471 African American controls; 1028 African Caribbean samples (from families)African American(935)African Caribbean(1028)ALL(1963)AFR(1963)ALL(1963)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., Extramural
2115710826rs980316TCrs980316199100304.00E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
2115710936rs980317TCrs980317199100301.60E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
2115716385rs7421482GTrs7421482199100302.70E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
2115723034rs12469474GArs12469474199100304.50E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
2115743547rs949577AGrs949577199100304.10E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
2128150924rs8179521AGrs8179521176114968.00E-07NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2128177377rs1158867CTrs1158867219078644.00E-36NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2128340855rs11693296GArs11693296217900087.00E-06Lung function, maximal expiration flow at 50% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGMYO7B
2138472227rs7561701CG,Trs7561701238296861.48E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
2138731765rs3791244GArs3791244176114967.00E-10NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2141638380rs10496855TGrs10496855201592424.90E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
2150397218rs7578361GTrs7578361231817889.89E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2150655221rs1012307ACrs1012307248242168.00E-07(African American/African Caribbean, female)1.44[1.25-1.67] 1,052 European ancestry male cases; 1,019 European ancestry female cases; 709 European ancestry male controls; 826 European ancestry female controls; 675 African ancestry male cases; 837 African ancestry female cases; 577 African ancestry male controls; 926 African ancestry female controls; 926 Latino male cases; 710 Latino female cases; 410 Latino male controls; 382 Latino female controlsAfrican(3015)European(3606)Latino(2428)ALL(9049)HIS(2428)AFR(3015)EUR(3606)ALL(9049)Asthma (sex interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
2150870450rs331125TCrs331125226949300.0000454NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2150877992rs732227TCrs732227226949300.000049NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2167475482rs4233808GArs4233808242801048.20E-05NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4233808-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2170115588rs2241190TCrs2241190206989757.70E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2170754854rs17554448AGrs17554448235413248.56E-05FEV1/FVC ratio0.19[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars17554448-AResearch Support, N.I.H., Extramural
2175602377rs733187GArs733187238296865.75E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
2177884232rs9287995CTrs9287995235413246.02E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars9287995-TResearch Support, N.I.H., Extramural
2178576681rs13428806GArs13428806209207762.68E-07Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2178603588rs3754993GCrs3754993209207769.05E-05Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2178604146rs4893839TCrs4893839209207763.27E-06Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2178605770rs11684634CArs11684634209207762.42E-08Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2178605770rs11684634CArs11684634209207766.00E-05AsthmaNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2178607273rs1866210GCrs1866210209207766.23E-05Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2178607359rs1866209GArs1866209209207765.79E-06Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2178612270rs998059ACrs998059209207761.31E-05Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2178836629rs2573088TCrs2573088209207761.06E-05Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
2181349830rs1072038AGrs1072038110220113.86E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1072038-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
2181996045rs13010713AGrs13010713211508785.00E-11NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2182019461rs13025711TCrs13025711231817882.47E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2191897540rs925847CTrs925847235413248.17E-05ppFEV10.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars925847-TResearch Support, N.I.H., Extramural
2195993306rs777734CArs777734239672694.39E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
2201113452rs17531061ACrs17531061227920823.90E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2201150040rs295137CTrs295137227920821.00E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars295137-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2201159988rs295139TArs295139227920826.80E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2201187775rs159320AGrs159320227920827.70E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2201195602rs295114CTrs295114227920826.00E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2201211716rs295142AGrs295142227920824.70E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2201214071rs1900706CArs1900706227920824.90E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2201247479rs7598349GArs7598349227920825.10E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2202497586rs1208082ACrs1208082235413248.49E-05ppFVC0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1208082-TResearch Support, N.I.H., Extramural
2204570092rs3181096CTrs3181096201592427.12E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
2204802578rs4675374TCrs4675374211508786.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2211495587rs12468557CTrs12468557235170429.00E-06adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
2213189729rs4673659ACrs4673659248242169.00E-07(Latino, female)1.42[1.23-1.64] 1,052 European ancestry male cases; 1,019 European ancestry female cases; 709 European ancestry male controls; 826 European ancestry female controls; 675 African ancestry male cases; 837 African ancestry female cases; 577 African ancestry male controls; 926 African ancestry female controls; 926 Latino male cases; 710 Latino female cases; 410 Latino male controls; 382 Latino female controlsAfrican(3015)European(3606)Latino(2428)ALL(9049)HIS(2428)AFR(3015)EUR(3606)ALL(9049)Asthma (sex interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
2216325768rs10498039CTrs10498039206989753.20E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2217488954rs6733115TCrs6733115238296862.43E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
2219046437rs4674267TCrs4674267239672697.29E-05NA1.33[1.33-2.38]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4674267-CResearch Support, Non-U.S. Gov'tCNA
2219080978rs6720449GArs6720449239672695.73E-05NA1.33[1.33-2.44]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6720449-GResearch Support, Non-U.S. Gov'tGNA
2220781006rs750764CTrs750764235413242.34E-05ppFEV10.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars750764-TResearch Support, N.I.H., Extramural
2220790637rs1007684AGrs1007684235413242.52E-05ppFEV10.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1007684-AResearch Support, N.I.H., Extramural
2223106018rs1367413GTrs1367413pha0031273.16E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGPAX3intron
2223167710rs6436310AGrs6436310pha0031287.60E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGCCDC140intron
2224044250rs1597167AGrs1597167217900083.69E-07Allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
2225558042rs1843834AGrs1843834239672694.00E-06NA2.14[1.54-2.96]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1843834-AResearch Support, Non-U.S. Gov'tGNA
2225558042rs1843834AGrs1843834239672699.31E-05NA1.34[1.34-2.43]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1843834-AResearch Support, Non-U.S. Gov'tGNA
2225574650rs10197382TCrs10197382239672695.72E-06NA1.52[1.52-2.89]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10197382-TResearch Support, Non-U.S. Gov'tCNA
2225634693rs1565073TGrs1565073239672693.31E-05NA1.46[1.46-2.88]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1565073-TResearch Support, Non-U.S. Gov'tGDOCK10
2225665193rs6717059CTrs6717059239672694.54E-05NA1.46[1.46-2.95]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6717059-CResearch Support, Non-U.S. Gov'tTDOCK10
2228373683rs4485561GTrs4485561239848881.15E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4485561-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2228378861rs10189795CTrs10189795239848882.97E-06NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10189795-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2228393168rs4972983CArs4972983239848888.62E-06NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4972983-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2228397566rs6731443TGrs6731443239848882.00E-06NA0.02[NA] unit decrease994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6731443-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2228418957rs13382948AGrs13382948239848882.75E-06NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars13382948-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2228438549rs4129709GArs4129709239848882.27E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4129709-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2228442208rs11674314CTrs11674314239848882.27E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars11674314-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2228443552rs7595130AGrs7595130239848882.24E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7595130-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2228445730rs7579157CTrs7579157239848882.23E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7579157-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2228448028rs11683662GArs11683662239848882.21E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars11683662-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2228451190rs7592613TCrs7592613239848882.25E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7592613-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2228808696rs1916804GTrs1916804201592429.98E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
2230326068rs11675728CTrs11675728235413247.22E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars11675728-TResearch Support, N.I.H., Extramural
2234180410rs3828309AGrs3828309211508782.00E-32NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2235055333rs16850525AGrs16850525pha0031287.98E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
2241769281rs4234121TGrs4234121235413243.25E-05ppFEV10.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4234121-AResearch Support, N.I.H., Extramural
2241769281rs4234121TGrs4234121235413245.32E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4234121-AResearch Support, N.I.H., Extramural
31533549rs7613331TArs7613331238296861.14E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
33614887rs9815663CTrs9815663225604792.00E-08NA0.17[NA] unit decrease573 European ancestry childrenEuropean(573)ALL(573)EUR(573)ALL(573)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmars9815663-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
38796547rs11706648ACrs11706648206989756.60E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
38826023rs6790467AGrs6790467pha0031278.66E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
38862925rs345065TCrs345065pha0031283.52E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
320147562rs4241546AGrs4241546231817888.98E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
322623604rs1531160CTrs1531160239672691.60E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tC,TNA
325131570rs13072262AGrs13072262231817882.01E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
326685539rs12496948GArs12496948227920824.00E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
333015469rs13314993GTrs13314993211508783.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
333015469rs13314993GTrs13314993219078643.00E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
335639826rs17033506GTrs17033506238296864.00E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
346235201rs13098911CTrs13098911211508783.00E-17NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
349721532rs3197999GArs3197999211508781.00E-12NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
354800316rs1820616TCrs1820616243154511.27E-05(EA)0.13[0.07-0.18] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1820616-TMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
354800316rs1820616TCrs1820616243154513.00E-06NA0.11[0.066-0.16] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
357431985rs2121743GArs2121743235413241.56E-05ppFVC0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2121743-TResearch Support, N.I.H., Extramural
357489591rs4681992CArs4681992235413244.01E-05ppFVC0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4681992-AResearch Support, N.I.H., Extramural
359265315rs9838009GTrs9838009227920828.40E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
359305064rs11130695ACrs11130695217900087.00E-06Lung function, forced expiratory volume in 1 second (FEV1)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractANA
363405972rs727777TCrs727777pha0031271.20E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATSYNPRintron
367298578rs872101GCrs872101238296863.71E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
374591012rs9836097AGrs9836097238296867.74E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
374616253rs11928037GTrs11928037226949300.00000827NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
374625123rs7630534AGrs7630534226949300.00000122NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
374672571rs17012697CTrs17012697226949300.0000597NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
374887781rs941304CTrs941304239672696.24E-05NA1.32[1.32-2.33]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars941304-AResearch Support, Non-U.S. Gov'tGNA
374955581rs12630469GArs12630469239672696.41E-05NA1.35[1.35-2.50]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12630469-AResearch Support, Non-U.S. Gov'tGNA
375166496rs9310315CTrs9310315239672695.26E-05NA1.33[1.33-2.38]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars9310315-TResearch Support, Non-U.S. Gov'tTNA
375222937rs9810161AGrs9810161239672693.94E-05NA1.35[1.35-2.44]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars9810161-GResearch Support, Non-U.S. Gov'tGNA
375245774rs9828201CTrs9828201239672699.86E-05NA1.32[1.32-2.38]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars9828201-TResearch Support, Non-U.S. Gov'tTNA
375257002rs4677485CTrs4677485239672696.86E-05NA1.33[1.33-2.38]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4677485-TResearch Support, Non-U.S. Gov'tTNA
376464685rs3849488GArs3849488238296867.74E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGROBO2
379884675rs9848056TCrs9848056235413244.67E-05ppFEV10.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars9848056-TResearch Support, N.I.H., Extramural
379888401rs4856360AGrs4856360235413244.07E-05ppFEV10.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4856360-AResearch Support, N.I.H., Extramural
382011680rs7644264CTrs7644264227920826.00E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
383038704rs35216186CTrs35216186238296861.24E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
398541116rs828616GArs828616210722012.00E-06Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGDCBLD2
3100476713rs9823506CTrs9823506238296866.00E-08NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTABI3BP
3103028245rs6788848CTrs6788848235413244.99E-05ppFEV10.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars6788848-TResearch Support, N.I.H., Extramural
3103348699rs2063485TCrs2063485235413241.34E-05FEV1/FVC ratio0.25[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2063485-TResearch Support, N.I.H., Extramural
3103348699rs2063485TCrs2063485235413247.18E-05ppFEV10.23[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2063485-TResearch Support, N.I.H., Extramural
3112269287rs2705520AGrs2705520238296862.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCATG3
3112991492rs3814399CA,G,Trs3814399238296868.95E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralC,TBOC
3116791023rs12634401TCrs12634401231817884.79E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
3116813492rs1357099TGrs1357099pha0031282.17E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
3119118796rs11712165TGrs11712165211508788.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
3119337198rs2272266CTrs2272266238296862.43E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGPLA1A
3119501960rs2472669TCrs2472669238296862.17E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNR1I2
3123571754rs1343700GArs1343700225615313.20E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3124102176rs1154799CTrs1154799209207763.55E-05Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
3124102317rs9832203GTrs9832203209207769.88E-05Asthma, early onset persistantNANA28 European ancestry cases; 19 European ancestry controls; 11 African ancestry cases; 4 African ancestry controls; 18 Hispanic cases; 14 Hispanic controls; 14 biracial samplesNOPOP(14)African(15)European(47)Hispanic(32)ALL(108)NOPOP(14)HIS(32)AFR(15)EUR(47)ALL(108)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270
3124443522rs3736388TCrs3736388239672695.87E-05NA1.35[1.35-2.44]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3736388-TResearch Support, Non-U.S. Gov'tTNA
3124486993rs614664CArs614664239848886.73E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars614664-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
3124501072rs702036AGrs702036239848887.58E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars702036-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3124528424rs848788TCrs848788239848881.30E-05NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars848788-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3131748098rs6790962GArs6790962pha0031283.32E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGCPNE4intron
3131759457rs3009511CTrs3009511pha0031282.69E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
3140953898rs2292400TCrs2292400217900082.60E-06Atopic sensitization in skin allergy testNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractAACPL2
3140978921rs3796259CTrs3796259217900083.14E-06Bronchial asthma in combination with atopic dermatitis and/or allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTACPL2
3140978921rs3796259CTrs3796259217900086.74E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTACPL2
3140978921rs3796259CTrs3796259217900089.76E-06Allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTACPL2
3140995801rs6775902CTrs6775902217900086.56E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTACPL2
3142888043rs17572584CTrs17572584206989759.70E-07AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3153495291rs1524548TGrs1524548pha0031273.28E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
3153499535rs9851119TCrs9851119pha0031276.93E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
3154376514rs12493149CTrs12493149231817888.46E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3155045430rs6440972CArs6440972247923828.00E-07NA0.35[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
3159665050rs17810546AGrs17810546211508784.00E-28NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
3159669994rs11918254CTrs11918254235413246.29E-05ppFEV10.19[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars11918254-TResearch Support, N.I.H., Extramural
3159678641rs7636840GTrs7636840235413243.58E-05ppFEV10.19[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7636840-TResearch Support, N.I.H., Extramural
3170769171rs4133045TCrs4133045235413243.50E-05ppFVC0.2[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4133045-AResearch Support, N.I.H., Extramural
3174278640rs9827557AGrs9827557235413241.12E-05ppFVC0.22[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars9827557-AResearch Support, N.I.H., Extramural
3174300045rs950636TCrs950636235413242.32E-05ppFVC0.22[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars950636-AResearch Support, N.I.H., Extramural
3175370599rs9868563CTrs9868563242801042.25E-05NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars9868563-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
3175410177rs1889261GArs1889261242801042.66E-05NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1889261-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
3177855632rs9883878GArs9883878238296861.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
3180550702rs6782299GTrs6782299213592102.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tT
3181255808rs6779474TCrs6779474201592429.90E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
3185618266rs4686399GArs4686399242801042.33E-05NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4686399-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
3186519136rs1648703ACrs1648703235170421.10E-05adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
3186519136rs1648703ACrs1648703235413247.83E-05FEV1/FVC ratio0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1648703-TResearch Support, N.I.H., Extramural
3186519136rs71528570AACrs1648703235170421.10E-05adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
3186519136rs71528570AACrs1648703235413247.83E-05FEV1/FVC ratio0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1648703-TResearch Support, N.I.H., Extramural
3186519141rs1656941ACrs1656941235170421.20E-05adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
3186519141rs1656941ACrs1656941235413247.44E-05FEV1/FVC ratio0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1656941-AResearch Support, N.I.H., Extramural
3188112554rs1464510CA,G,Trs1464510211508783.00E-40NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3188112554rs1464510CA,G,Trs1464510219078643.00E-40NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3193891012rs11711981CTrs11711981225615312.19E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4116981rs17745701CGrs17745701231817887.00E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
41053172rs6839931TCrs6839931110220112.09E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars6839931-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
41058659rs7669622TCrs7669622110220114.53E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7669622-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
41059202rs6827357ACrs6827357110220115.15E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars6827357-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
42954717rs7667661GArs7667661239672692.50E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNOP14
43063817rs7694687CTrs7694687239672691.70E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
44809353rs4689941ACrs4689941239672691.60E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
411268830rs4697861GCrs4697861225027970.000659NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
425739169rs4328902TCrs4328902227920826.10E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
428687406rs7663065AGrs7663065235413245.43E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7663065-AResearch Support, N.I.H., Extramural
431354090rs4692508ACrs4692508238296866.36E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
436066470rs11940540GCrs11940540238296869.58E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
437846939rs2303409ACrs2303409238296864.23E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTPGM2
439088341rs35141484ACrs35141484238296863.00E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralAKLHL5
440279534rs9683756GArs9683756pha0031275.18E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
441082483rs10516997GCrs10516997213592102.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tG
442237898rs4861175GArs4861175239848882.60E-04NANANA994 European ancestry asthma casesEuropean(994)ALL(994)EUR(994)ALL(994)Airway hyperresponsivenessHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4861175-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
447101223rs1866990GArs1866990239672692.68E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGGABRB1
447932661rs4695314GArs4695314238296863.56E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
456475338rs3805383GArs3805383235413242.35E-05ppFEV10.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars3805383-AResearch Support, N.I.H., Extramural
458964422rs6839025GArs6839025pha0031279.15E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAG,ANANA
458994906rs4864645ACrs4864645pha0031279.41E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
459074656rs2060321GArs2060321pha0031274.62E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
459094592rs4353961GArs4353961pha0031276.72E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
459109055rs12511928GArs12511928pha0031275.27E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
459156514rs17237651AGrs17237651pha0031275.27E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
459213845rs17218161TCrs17218161238296862.00E-08NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
462244228rs17219773GTrs17219773206989754.56E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
465680034rs10005234TArs10005234238296863.82E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
466496170rs7659227AGrs7659227218045498.89E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
466499016rs11735820TGrs11735820218045492.27E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
468598998rs1843593TCrs1843593235413245.30E-05ppFEV10.2[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1843593-TResearch Support, N.I.H., Extramural
469214926rs17592868TCrs17592868235413241.39E-05ppFVC0.35[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars17592868-TResearch Support, N.I.H., Extramural
471051031rs17652789CTrs17652789225027970.0000782NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
471051407rs1514401TArs1514401225027970.000439NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
471052339rs6839328CTrs6839328225027970.0000683NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
471083209rs1842483AGrs1842483225027970.000446NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
472028545rs7685921AGrs7685921243154519.00E-07(EA)0.12[0.069-0.163] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7685921-GMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
472028545rs7685921AGrs7685921243154519.00E-07NA0.12[0.069-0.163] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
472393391rs1530976GCrs1530976238296862.68E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCSLC4A4
479887043rs13150370TCrs13150370225615313.05E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
484578707rs10026591GArs10026591225027970.000542NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
487023394rs12640395AGrs12640395226949300.0000655NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
487027819rs11943376TCrs11943376226949300.000072NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
487076360rs6822478TCrs6822478pha0031279.68E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATMAPK10intron
494753879rs7699958GTrs7699958231817886.24E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4104529274rs4580655GArs4580655213592101.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tA
4113855477rs12500579CGrs12500579243154515.00E-13(EA)0.42[0.31-0.53] unit decrease5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12500579-GMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
4113855477rs12500579CGrs12500579243154518.00E-08NA0.19[0.12-0.26] unit decrease5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
4119863476rs1472066AGrs1472066239672698.00E-06NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGSYNPO2
4119874487rs1038770GArs1038770239672698.66E-06NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGSYNPO2
4119877794rs12508843TGrs12508843239672691.10E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGSYNPO2
4120953245rs10006038TCrs10006038217900085.00E-06Lung function, maximal expiration flow at 25% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTNA
4123115502rs13151961AGrs13151961211508782.00E-27NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4123132492rs4505848AGrs4505848219078645.00E-13NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4126967979rs6534528AGrs6534528227920823.90E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4126973044rs1320269TGrs1320269227920822.60E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4126996870rs12509991CTrs12509991227920829.70E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4126996974rs10518485CTrs10518485227920821.40E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4127001808rs4382051AGrs4382051227920828.00E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4127006583rs17010666ACrs17010666227920824.20E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4127033186rs7667104AGrs7667104227920825.80E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4127036380rs7677190TGrs7677190227920826.60E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4127041554rs7685518AGrs7685518227920824.90E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4127065892rs565659ACrs565659227920828.10E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4127074758rs1586150CTrs1586150227920829.10E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4130523279rs628527AGrs628527239672691.10E-04NA1.27[1.27-2.09]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars628527-GResearch Support, Non-U.S. Gov'tANA
4131727377rs2312337ACrs2312337pha0031285.61E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
4139611302rs1505863CTrs1505863184015940.00001NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
4142711243rs17701271CArs17701271235082663.00E-04Recessive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars17701271-AResearch Support, N.I.H., ExtramuralCNA
4143907480rs1588408GArs1588408218045487.76E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4143911483rs1510140CTrs1510140218045487.76E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4143936903rs1104696AGrs1104696218045484.21E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4143946132rs1588411TCrs1588411218045484.21E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4143947047rs4690752AGrs4690752218045484.21E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG,A
4143959584rs1113094GArs1113094218045484.50E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4143972745rs4690760CTrs4690760218045481.34E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4144003159rs7686660TGrs7686660218045482.00E-12NA1.16[1.11-1.21]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7686660-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4144060464rs7666785AGrs7666785218045482.74E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4144069561rs4337690GTrs4337690218045483.03E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4144073912rs11100775AGrs11100775218045485.82E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4144086245rs4132266GArs4132266218045482.74E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4144104906rs11100780GArs11100780218045482.40E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4144165951rs17017425CTrs17017425218045482.89E-05NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4144171748rs300934TGrs300934218045484.55E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4144182073rs10519678CTrs10519678218045482.76E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4144187380rs893929GArs893929218045482.33E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4144193117rs763918TGrs763918218045486.58E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4144207686rs17686361GArs17686361218045485.52E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4144240473rs300905AGrs300905218045482.71E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4144273884rs300916GTrs300916218045485.15E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4144285683rs3805254AGrs3805254218045489.55E-05NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4144293524rs12649592GArs12649592218045485.30E-05NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4144295952rs3805251CTrs3805251218045488.24E-05NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4144319745rs1397528GArs1397528218045481.42E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4144325021rs10519691ACrs10519691218045481.81E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4144326385rs1397527GTrs1397527218045482.37E-05NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4144340098rs4690785TCrs4690785218045484.67E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC,T
4144357737rs3805236AGrs3805236218045487.00E-08NA1.12[1.08-1.17] 1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3805236-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4145511875rs7670758AGrs7670758235413249.50E-05ppFEV10.14[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7670758-AResearch Support, N.I.H., Extramural
4152944433rs17028407CArs17028407239672699.59E-05NA1.41[1.41-3.13]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars17028407-CResearch Support, Non-U.S. Gov'tCNA
4152960983rs7434739GArs7434739239672693.54E-05NA1.35[1.35-2.38]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7434739-GResearch Support, Non-U.S. Gov'tGNA
4154415184rs13119846TCrs13119846235413242.02E-05ppFVC0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars13119846-TResearch Support, N.I.H., Extramural
4158724848rs727755CTrs727755235413249.57E-05ppFEV10.14[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars727755-AResearch Support, N.I.H., Extramural
4158731019rs7434819GArs7434819235413247.34E-05ppFEV10.14[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7434819-AResearch Support, N.I.H., Extramural
4158782030rs9991982CTrs9991982231817883.80E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4160267334rs11723634TCrs11723634231817881.70E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4161565370rs981516AC,G,Trs981516225615312.27E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4162907833rs359486TCrs359486201592426.11E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
4168433754rs17053323AGrs17053323239672695.37E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
4175796630rs1121336TCrs1121336231817885.76E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4176285962rs2333166TCrs2333166239672696.37E-05NA1.54NA404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2333166-TResearch Support, Non-U.S. Gov'tTNA
4181526927rs1559101AGrs1559101pha0031277.24E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
4185315792rs3756089CTrs3756089235413248.79E-05ppFEV10.26[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars3756089-TResearch Support, N.I.H., Extramural
4186299758rs1048329GArs1048329206989753.10E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4186299985rs1288548GArs1288548206989758.70E-07AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4186809714rs4862585CTrs4862585231817885.90E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
51203437rs13159461GArs13159461201592423.89E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
51689029rs16883212ACrs16883212225027970.00077NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
52507645rs6896543ATrs6896543225027970.000527NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
52533617rs6875477AGrs6875477239672691.20E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tA,GNA
54292616rs1039603TCrs1039603206989755.00E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
54343987rs261159CTrs261159206989753.40E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
54361120rs261137CTrs261137206989751.20E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
54365468rs261119GArs261119206989754.20E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
54369887rs261125GTrs261125206989756.60E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
56462338rs272474AGrs272474231817883.78E-08NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
57155958rs12659620TCrs12659620235413245.56E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars12659620-TResearch Support, N.I.H., Extramural
57546411rs10512928CTrs10512928110220117.32E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10512928-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
59226440rs16882243CGrs16882243238296869.49E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCSEMA5A
59723470rs16883448GArs16883448237067090.0000033NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tALOC285692
510148421rs6884905CTrs6884905110220119.18E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars6884905-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
511518226rs4702810CTrs4702810231817882.12E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
512652832rs7721328TCrs7721328231817885.99E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
512699253rs4558991CGrs4558991231817884.49E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
515783596rs10044254AGrs10044254244860699.00E-08NA1.19[NA] unit increase124 European ancestry individualsEuropean(124)ALL(124)EUR(124)ALL(124)Asthma (corticosteroid response)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, N.I.H., ExtramuralAFBXL7
517293761rs298568ACrs298568227920822.40E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
517296431rs2652653AGrs2652653227920822.20E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
517298004rs298566CTrs298566227920822.10E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
531818948rs4867084GArs4867084210722014.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tAPDZD2
533954511rs2287949TCrs2287949239672691.40E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
533954511rs387906317TGTrs2287949239672691.40E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
533955252rs2113097TCrs2113097239672691.40E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGSLC45A2
533958910rs1010872ACrs1010872239672691.50E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCSLC45A2
534525931rs10075914AGrs10075914110220117.33E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10075914-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
538867732rs395157CTrs395157239672696.94E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGOSMR
540237374rs36019094CArs36019094217900082.21E-06Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractANA
540237843rs34868670TCrs34868670217900089.58E-06Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTNA
540392728rs4613763TCrs4613763211508787.00E-27NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
541185361rs4245976TCrs4245976210722017.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCC6
556343247rs16886678AGrs16886678237067090.0000055NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
559369794rs1588265AGrs1588265194269553.00E-08NA1.18[1.08-1.30] 422 cases; 1,533 controlsNOPOP(1955)ALL(1955)NOPOP(1955)ALL(1955)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1588265-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
559369794rs1588265AGrs1588265206989755.11E-07AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
559369794rs1588265AGrs1588265219078642.50E-08NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
559383886rs2548659AGrs2548659194269551.50E-07NANANA422 cases; 1,533 controlsNOPOP(1955)ALL(1955)NOPOP(1955)ALL(1955)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
559383886rs2548659AGrs2548659206989752.07E-07AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
559439082rs1544791TCrs1544791194269559.70E-07NANANA422 cases; 1,533 controlsNOPOP(1955)ALL(1955)NOPOP(1955)ALL(1955)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
559439082rs1544791TCrs1544791206989751.16E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
559445137rs983280CTrs983280194269554.80E-07NANANA422 cases; 1,533 controlsNOPOP(1955)ALL(1955)NOPOP(1955)ALL(1955)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
559445137rs983280CTrs983280206989755.71E-07AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
559467203rs2910830GArs2910830206989757.79E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
562541894rs346416CArs346416210722017.30E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
566807042rs4976079CTrs4976079227920821.50E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
566807910rs7715410CArs7715410227920824.10E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
566814842rs10940113TCrs10940113227920826.10E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
566820274rs6414806CTrs6414806227920828.10E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
566912233rs4976096CTrs4976096227920823.40E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
576233004rs1700687CTrs1700687206989753.90E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
576264982rs1875999TCrs1875999206989758.80E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
576324766rs17682661TCrs17682661231817886.69E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
579355471rs401302CTrs401302pha0031277.08E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGTHBS4intron
587430517rs7716850CTrs7716850238296866.11E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
587525513rs7716599AGrs7716599pha0031288.01E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAATMEM161Bintron
593624507rs6859083CTrs6859083247923827.99E-06NA0.32[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTKIAA0825
593643170rs10491400TGrs10491400247923827.80E-06NA0.32[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTKIAA0825
593648131rs17083580GCrs17083580238296862.52E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGKIAA0825
593697852rs2434364CTrs2434364247923827.00E-06NA0.33[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCKIAA0825
5109348449rs17162540AGrs17162540pha0031274.72E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
5110401872rs1837253TCrs1837253208605037.52E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5110401872rs1837253TCrs1837253218045481.00E-16NA1.17[1.13-1.22]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1837253-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5110401872rs1837253TCrs1837253218045491.00E-14NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
5110401872rs1837253TCrs1837253225615315.52E-06NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5110401872rs1837253TCrs1837253226949300.00076NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5110405675rs3806932AGrs3806932219078643.00E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5110464008rs1043828TCrs1043828219078641.10E-08NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5110467499rs1438673CTrs1438673219078643.20E-06NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
5110470137rs6594499CArs6594499231817881.80E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
5126487366rs2159424GArs2159424238296862.52E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
5128190750rs1496348CArs1496348184015940.0007NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
5130883996rs17671387TA,C,Grs17671387226949300.000052NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5131075921rs4705893CTrs4705893226949300.0000449NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5131394738rs2073506CTrs2073506226949300.000069NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5131407044rs25879AGrs25879226949300.0000645NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
5131615966rs7721296TCrs7721296226949300.0000761NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5131649222rs2073838GArs2073838226949300.00000129NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5131675981rs2306772CTrs2306772226949300.00000217NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5131723288rs2073643TCrs2073643208605032.00E-07NA1.11[1.06-1.15] 10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2073643-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5131723288rs2073643TCrs2073643219078642.20E-07NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5131723288rs2073643TCrs2073643225615312.20E-07NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5131723288rs2073643TCrs2073643242415371.40E-05NA1.25[1.13-1.38]1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2073643-TNATSLC22A5
5131770805rs2188962CTrs2188962211508782.00E-18NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5131796922rs11745587GArs11745587225615312.00E-06NA1.26[1.15-1.39] 933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5131829297rs2549003GArs2549003248242169.00E-07(European, male)1.33[1.18-1.49] 1,052 European ancestry male cases; 1,019 European ancestry female cases; 709 European ancestry male controls; 826 European ancestry female controls; 675 African ancestry male cases; 837 African ancestry female cases; 577 African ancestry male controls; 926 African ancestry female controls; 926 Latino male cases; 710 Latino female cases; 410 Latino male controls; 382 Latino female controlsAfrican(3015)European(3606)Latino(2428)ALL(9049)HIS(2428)AFR(3015)EUR(3606)ALL(9049)Asthma (sex interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
5131901225rs2244012AGrs2244012201592423.00E-07NA1.64[1.36-1.97] 607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2244012-CMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
5131929594rs2897443GTrs2897443201592422.74E-06NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
5131929594rs2897443GTrs2897443208605031.47E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5131932753rs17622991GArs17622991236662770.0000107NANANA745 African American cases; 3238 African American controlsAfrican American(3983)ALL(3983)AFR(3983)ALL(3983)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5131969874rs6871536TCrs6871536201592429.03E-07NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
5131969874rs6871536TCrs6871536208605031.81E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5131969874rs6871536TCrs6871536219078642.40E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5131969874rs6871536TCrs6871536242415378.00E-07NA1.17[1.10-1.25] 1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6871536-CNATRAD50
5131977127rs2240032CTrs2240032208605033.47E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5131995843rs1295686TCrs1295686208605031.00E-07NA1.15[1.09-1.20] 10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1295686-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
5131995843rs1295686TCrs1295686219078641.40E-07NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
5131995843rs1295686TCrs1295686225615311.40E-07NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
5131995843rs1295686TCrs1295686242415372.00E-06NA1.31[1.17-1.48] 1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1295686-TNAAIL13
5131995964rs20541AGrs20541208605031.24E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5131995964rs20541AGrs20541226949300.000417NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5132655625rs733023AGrs733023pha0031282.68E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACFSTL4intron
5133003135rs11242168TCrs11242168217900081.00E-06Lung function, maximal expiration flow at 25% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
5133003135rs11242168TCrs11242168217900082.00E-06Lung function, maximal expiration flow at 50% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
5133003449rs6865119GTrs6865119217900081.00E-06Lung function, maximal expiration flow at 50% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTNA
5133003449rs6865119GTrs6865119217900082.00E-06Lung function, maximal expiration flow at 25% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTNA
5133531449rs10051026CTrs10051026235413247.16E-05ppFVC0.21[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars10051026-TResearch Support, N.I.H., Extramural
5133551445rs13187105TGrs13187105235413245.54E-05ppFVC0.21[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars13187105-TResearch Support, N.I.H., Extramural
5141445980rs6867913GArs6867913225615314.00E-06NA1.33[1.18-1.49] 933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5141479065rs11167764ACrs11167764219078642.00E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5143096916rs9324928GArs9324928pha0031278.96E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
5146652943rs987651AGrs987651239672694.14E-05NA1.35[1.35-2.38]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars987651-TResearch Support, Non-U.S. Gov'tTSTK32A
5146658253rs1549881AGrs1549881239672697.60E-05NA1.32[1.32-2.30]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1549881-AResearch Support, Non-U.S. Gov'tGSTK32A
5146675133rs13170855CTrs13170855239672697.10E-05NA1.32[1.32-2.30]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars13170855-CResearch Support, Non-U.S. Gov'tCSTK32A
5147520415rs4705227GArs4705227217900086.21E-06Allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractANA
5150258867rs11747270AGrs11747270211508783.00E-16NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5150432153rs2112635CTrs2112635226949300.000425NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5150438988rs1422673CTrs1422673226949300.000000272NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5150438988rs1422673CTrs1422673pha0031271.78E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATTNIP1intron
5150440097rs2233287GArs2233287226949300.0000865NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5150440097rs2233287GArs2233287pha0031275.83E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACTNIP1intron
5150450236rs4958881TCrs4958881226949300.000158NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5150451650rs3792785TCrs3792785226949300.0000611NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
5150451650rs3792785TCrs3792785pha0031276.18E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAATNIP1intron
5150455732rs3792783AGrs3792783226949300.0000526NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5150458146rs10036748CTrs10036748226949300.00000114NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5150458146rs10036748CTrs10036748pha0031273.44E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATTNIP1intron
5150462638rs13168551TCrs13168551226949300.000551NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5150739002rs6876572TCrs6876572225615311.60E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5151481730rs154104AGrs154104110220113.78E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars154104-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
5153772289rs10064618GArs10064618218045494.44E-04NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
5154442093rs10059123ACrs10059123238296869.55E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
5156155155rs456290CTrs456290213592102.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tC
5156817266rs17599222GTrs17599222199100304.10E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
5158814533rs10045431ACrs10045431211508784.00E-13NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
5159017398rs6882632CTrs6882632238296863.67E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
5159297173rs11954917CTrs11954917199100286.00E-04AsthmaNANA464 African American cases; 471 African American controls; 1028 African Caribbean samples (from families)African American(935)African Caribbean(1028)ALL(1963)AFR(1963)ALL(1963)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., Extramural
5159298312rs10077860TArs10077860199100284.10E-05AsthmaNANA464 African American cases; 471 African American controls; 1028 African Caribbean samples (from families)African American(935)African Caribbean(1028)ALL(1963)AFR(1963)ALL(1963)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., Extramural
5159364998rs10515807GArs10515807199100283.57E-06AsthmaNANA464 African American cases; 471 African American controls; 1028 African Caribbean samples (from families)African American(935)African Caribbean(1028)ALL(1963)AFR(1963)ALL(1963)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., Extramural
5166639905rs17495520CTrs17495520235082663.00E-04Additive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars17495520-TResearch Support, N.I.H., ExtramuralCNA
5169357503rs259892TGrs259892110220111.10E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars259892-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
5169481492rs13361200TCrs13361200110220112.98E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars13361200-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
5169731198rs315782GArs315782239672693.36E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
5169743612rs4867956CTrs4867956201592429.54E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
5174901052rs6861032AGrs6861032201592422.29E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
5177357964rs4958980AGrs4958980227920827.50E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5177373525rs7730346TGrs7730346227920827.00E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tNA
63415302rs4452682GArs4452682227920823.20E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
63665573rs9502039CTrs9502039239672698.71E-05NA1.32[1.32-2.33]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars9502039-TResearch Support, Non-U.S. Gov'tTNA
64553691rs10484836CTrs10484836pha0031272.00E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
64915423rs4144547TArs4144547231817882.17E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
68871713rs4566922CTrs4566922244060732.90E-06NA1.27[1.15-1.27]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
612388165rs994565CTrs994565239672691.50E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tC,TNA
615093021rs6906466CArs6906466237067090.0000049NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
619297457rs12205836GArs12205836pha0031288.30E-06phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAA,GNANA
620728731rs6908425TCrs6908425211508789.00E-10NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
621039951rs9295489AGrs9295489237067090.0000072NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGCDKAL1
624223579rs4052671TCrs4052671231802726.83E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTDCDC2
624261060rs870601TCrs870601231802723.88E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTDCDC2
624266739rs6456601CTrs6456601231802723.96E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCDCDC2
624274117rs12055879CArs12055879231802725.88E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCDCDC2
624280101rs3789224GArs3789224231802723.07E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tGDCDC2
624285571rs2328208CTrs2328208231802725.11E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCDCDC2
624286952rs9379650TCrs9379650231802723.63E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTDCDC2
624288724rs17302729GArs17302729231802726.61E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tADCDC2
624292282rs3804327CTrs3804327244060731.80E-06NA1.37[1.20-1.56]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
628302784rs1416920AGrs1416920235413249.46E-05FEV1/FVC ratio0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1416920-TResearch Support, N.I.H., Extramural
629655113rs2747454GArs2747454217900082.00E-06Lung function, maximal expiration flow at 50% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
631122500rs130065GArs130065208605033.13E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
631243884rs3130696GArs3130696235413247.34E-05FEV1/FVC ratio0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars3130696-AResearch Support, N.I.H., Extramural
631312326rs3134792TGrs3134792219078641.00E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
631499603rs3853601CGrs3853601217900082.20E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGDDX39B
631499603rs3853601CGrs3853601217900083.82E-06Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGDDX39B
631499603rs3853601CGrs3853601217900085.57E-06Bronchial asthma in combination with atopic dermatitis and/or allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGDDX39B
631499603rs3853601CGrs3853601217900085.73E-07Atopic sensitization in skin allergy testNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGDDX39B
631528951rs17200733AGrs17200733217900082.98E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractALOC100287329
632155581rs204993AGrs204993218045482.00E-15NA1.17[1.12-1.21]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars204993-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
632184345rs404860TCrs404860218045484.00E-23NA1.21[1.16-1.25]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars404860-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
632338695rs3129943AGrs3129943218045483.00E-15NA1.17[1.12-1.21]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3129943-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
632338695rs3129943AGrs3129943244060739.80E-04NA1.24[1.09-1.40]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
632341473rs9268403TCrs9268403231817881.82E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
632358513rs3117098GArs3117098218045485.00E-12NA1.16[1.11-1.21]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3117098-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
632375973rs3763309CArs3763309219078642.80E-07NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
632379489rs9268516CTrs9268516230284831.00E-08NA1.15[1.10-1.21] 1,716 European ancestry cases; 16,888 European ancestry controlsEuropean(18604)ALL(18604)EUR(18604)ALL(18604)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars9268516-TResearch Support, Non-U.S. Gov'tResearch Support, N.I.H., IntramuralC
632384721rs9268542AGrs9268542201592428.55E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
632411523rs2239804TCrs2239804201592422.80E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
632414273rs3129890TCrs3129890218045485.00E-13NA1.15[1.11-1.20]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3129890-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tNA
632427748rs9268831CTrs9268831231817887.23E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
632429643rs9268853TCrs9268853231817889.55E-07NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
632429758rs9268858TCrs9268858231817881.13E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
632433167rs2395185GTrs2395185201592428.73E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
632433167rs2395185GTrs2395185226949300.00077NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
632570400rs2516049TCrs2516049201592422.62E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
632604372rs9272346GArs9272346231817882.00E-08AdultNANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
632605884rs2187668CTrs2187668211508781.00E-50NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
632620283rs17843604CTrs17843604208605031.55E-10NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
632625869rs9273349TCrs9273349208605037.00E-14NA1.18[1.13-1.24]10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars9273349-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
632625869rs9273349TCrs9273349219078647.00E-14NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
632625869rs9273349TCrs9273349225615317.00E-14NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
632627714rs1063355TGrs1063355201592429.55E-06NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
632657578rs7774434TCrs7774434239672691.10E-04NA1.28[1.28-2.22]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7774434-TResearch Support, Non-U.S. Gov'tCNA
632658079rs7775228TCrs7775228218045485.00E-15NA1.17[1.12-1.21]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7775228-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT,C
632663564rs5000634AGrs5000634201592429.16E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
632665728rs9275312AGrs9275312201592421.13E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
632687973rs9275698AGrs9275698218045485.00E-12NA1.18[1.12-1.24]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars9275698-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA,G
632804909rs241425AGrs241425219078649.90E-07NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
632961361rs9500927GArs9500927218045484.00E-09NA1.13[1.09-1.18] 1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars9500927-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
633042880rs987870AGrs987870218145172.00E-10NA1.4[1.26-1.55]938 Japanese ancestry cases; 2,376 Japanese ancestry controlsJapanese(3314)ALL(3314)ASN(3314)ALL(3314)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars987870-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
633046915rs1431402TArs1431402231802721.11E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tAHLA-DPA1
633048661rs1042151AGrs1042151231802725.00E-07NA2.4[1.68-3.42] 117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmars1042151-GResearch Support, Non-U.S. Gov'tAHLA-DPB1
633059796rs2281389AGrs2281389231802726.98E-07NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
633074288rs3128927CTrs3128927231802725.86E-06NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
633075443rs910320CTrs910320231802721.01E-06NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
633075635rs3117230AGrs3117230231802721.21E-06NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
633084671rs3129294ACrs3129294231802722.09E-06NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
633086448rs1883414GArs1883414231802729.43E-06NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
633089196rs3129286GArs3129286231802723.58E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
633097423rs3129270CTrs3129270231802721.76E-06NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
633097614rs3129269CArs3129269231802721.93E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
633098276rs6901221ACrs6901221231802721.41E-06NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
636932571rs1046279TCrs1046279239672691.60E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCPI16
644769237rs7770848TGrs7770848238296862.00E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
645543338rs2280229CTrs2280229201592429.15E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
646127836rs2295017TArs2295017210722015.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tAENPP5
648513035rs9463425AGrs9463425206989759.70E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
649891258rs4715153TCrs4715153pha0031277.13E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
649902734rs6927196TCrs6927196pha0031277.60E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
652856179rs6904771AGrs6904771pha0031286.23E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAAGSTA4intron
669675867rs12191480TCrs12191480pha0031283.96E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATBAI3intron
673090537rs2807510GArs2807510238296863.42E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralARIMS1
673351870rs12200468AGrs12200468225615311.47E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
673405265rs17729195TCrs17729195217900081.00E-06Lung function, forced expiratory volume in 1 second (FEV1)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTKCNQ5
673431969rs719830AGrs719830217900084.00E-06Lung function, forced expiratory volume in 1 second (FEV1)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractAKCNQ5
673573771rs1935521AGrs1935521238296867.10E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCKCNQ5
676194895rs1932523TCrs1932523210722013.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTFILIP1
682020990rs10455382GTrs10455382226079920.000094NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
682072436rs4706889AGrs4706889226079920.00064NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
682091661rs9341883TGrs9341883226079920.00048NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
682099191rs2323252ACrs2323252226079920.00035NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
682287685rs1361549GArs1361549226079920.00000187NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
682287685rs1361549GArs1361549pha0031285.24E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
685178268rs9362054TCrs9362054235413248.68E-05FEV1/FVC ratio0.14[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars9362054-TResearch Support, N.I.H., Extramural
686944599rs7765374GArs7765374206989757.34E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
690926612rs10806425CArs10806425211508784.00E-10NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
690973159rs1847472CArs1847472219078645.00E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
691038726rs6926330GArs6926330226079920.000037NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
691743110rs9345075AGrs9345075226079920.0000161NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
691876805rs6925314AGrs6925314217900083.32E-06Bronchial asthma in combination with atopic dermatitis and/or allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
691876805rs6925314AGrs6925314217900085.25E-06Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
691956663rs2811670TCrs2811670247923827.00E-06NA0.05[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
694460497rs1414614TCrs1414614226079920.00062NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
694461990rs9363108CTrs9363108226079920.00062NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
695152928rs2207428GArs2207428226079920.000042NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
695358968rs9363229GTrs9363229226079920.0000167NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
695390186rs10498989CTrs10498989226079920.00000856NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
6100138561rs576231CTrs576231226079920.0000167NANANA355 African American cases; 444 African American controlsAfrican American(799)ALL(799)AFR(799)ALL(799)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6106435269rs7746082GCrs7746082211508782.00E-10NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
6110057219rs3799852AGrs3799852239672694.55E-05NA1.37[1.37-2.49]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3799852-AResearch Support, Non-U.S. Gov'tGFIG4
6111390344rs6935864ACrs6935864226949300.0000226NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6113479335rs2473967GTrs2473967238296862.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
6119685952rs1295378TCrs1295378238296862.52E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
6121766286rs11961755GArs11961755217900083.00E-06Lung function, forced vital capacity (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGGJA1
6126022602rs1777220GTrs1777220226949300.0000598NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
6128278798rs802734AGrs802734211508783.00E-14NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6128278798rs802734AGrs802734219078643.00E-14NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6130787776rs11751990CTrs11751990206989754.97E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC,T
6132466452rs1321267ACrs1321267235413245.46E-05ppFEV10.14[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1321267-AResearch Support, N.I.H., Extramural
6134369424rs2811686TGrs2811686227920829.80E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6135592211rs11968112GArs11968112230408850.000009NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
6135596873rs11964349CTrs11964349230408850.0000015NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
6137674040rs1022400TCrs1022400pha0031286.52E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
6137973068rs2327832AGrs2327832211508784.00E-19NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6139227530rs1212985TGrs1212985231817887.42E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6139774853rs3010301AGrs3010301235413242.65E-05ppFEV10.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars3010301-TResearch Support, N.I.H., Extramural
6140461008rs169291GCrs169291110220115.93E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars169291-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
6147091074rs17535206TGrs17535206227920822.00E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6149762537rs2179367AGrs2179367217328293.00E-07NA1.23[1.14-1.32] 856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseasers2179367-GResearch Support, Non-U.S. Gov'tTNA
6151672285rs13212161AGrs13212161217900089.37E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractAAKAP12
6152313146rs9340941CTrs9340941199100306.90E-04Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
6153694029rs2171249TCrs2171249231817888.45E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6154628854rs7739184CGrs7739184231817881.57E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
6154827861rs7768635CTrs7768635226949300.0000701NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6155371513rs9322495TCrs9322495pha0031279.90E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
6156540417rs2820406GArs2820406239672699.53E-05NA1.28[1.28-2.13]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2820406-GResearch Support, Non-U.S. Gov'tANA
6159465977rs1738074TCrs1738074211508783.00E-15NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6165565895rs2675724ACrs2675724248242162.00E-07(Latino, female)1.44[1.26-1.66] 1,052 European ancestry male cases; 1,019 European ancestry female cases; 709 European ancestry male controls; 826 European ancestry female controls; 675 African ancestry male cases; 837 African ancestry female cases; 577 African ancestry male controls; 926 African ancestry female controls; 926 Latino male cases; 710 Latino female cases; 410 Latino male controls; 382 Latino female controlsAfrican(3015)European(3606)Latino(2428)ALL(9049)HIS(2428)AFR(3015)EUR(3606)ALL(9049)Asthma (sex interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
6166534742rs6456042ACrs6456042225388056.00E-06NANANA418 European ancestry casesEuropean(418)ALL(418)EUR(418)ALL(418)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNARandomized Controlled TrialResearch Support, N.I.H., ExtramuralComparative Study
6167186024rs17590608TCrs17590608227920824.30E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6167215384rs7754623CArs7754623227920828.80E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6167218762rs2178806CTrs2178806227920821.00E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6167437988rs2301436CTrs2301436211508781.00E-12NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6169202852rs9364299GArs9364299235413249.96E-05ppFEV10.14[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars9364299-AResearch Support, N.I.H., Extramural
6169440940rs7741751CTrs7741751110220112.25E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7741751-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
6169935826rs16888111GArs16888111238296865.75E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGWDR27
6169988672rs7740799TGrs7740799231817881.86E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
78007509rs37972TCrs37972219918917.00E-04Response to inhaled glucocorticoids for asthma measured as change in forced expiratory volume (FEV1)NANA1209 European ancestry samples (from trios)European(1209)ALL(1209)EUR(1209)ALL(1209)Response to glucocorticoid therapy in asthmaHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
78007876rs37973GArs37973219918917.00E-04Response to inhaled glucocorticoids for asthma measured as change in forced expiratory volume (FEV1)NANA1209 European ancestry samples (from trios)European(1209)ALL(1209)EUR(1209)ALL(1209)Response to glucocorticoid therapy in asthmaHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
78859094rs10245651GArs10245651pha0031272.00E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
713253069rs6973933GArs6973933217900089.00E-06Lung function, forced expiratory volume in 1 second (FEV1)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractANA
722358234rs12333614CTrs12333614237067090.0000068NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTRAPGEF5
724240165rs886448GArs886448238296867.00E-08NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
725722313rs2214976CTrs2214976230408850.0000087NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
725751792rs11489283AGrs11489283230408850.0000036NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
726427889rs1406593GArs1406593235413247.64E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1406593-TResearch Support, N.I.H., Extramural
726532145rs757393CTrs757393201592426.26E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
726536913rs3180361AGrs3180361201592425.83E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
726543316rs1859600GArs1859600201592425.38E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
728420703rs2058397CTrs2058397pha0031287.27E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACCREB5intron
729135569rs2286992CTrs2286992239672697.39E-05NA1.32[1.32-2.27]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2286992-CResearch Support, Non-U.S. Gov'tCCPVL
729140213rs12670165CTrs12670165239672698.94E-05NA1.3[1.30-2.27]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12670165-CResearch Support, Non-U.S. Gov'tCCPVL
732700562rs1839581GArs1839581pha0031286.27E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGDPY19L1P1intron
735830920rs7792246ACrs7792246231817881.21E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
737989095rs16879765CTrs16879765217328296.00E-39NA1.98[1.78-2.18]856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseasers16879765-AResearch Support, Non-U.S. Gov'tCEPDR1
742018699rs7802385TCrs7802385206989756.40E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
743433870rs10951730GArs10951730235413249.58E-05ppFEV10.24[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars10951730-AResearch Support, N.I.H., Extramural
744222802rs1990458CTrs1990458239672695.24E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGGCK
744231216rs3757840TGrs3757840239672697.05E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
750269672rs1456893GArs1456893211508785.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
754039000rs9918659AGrs9918659238296863.82E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
769971020rs3094893TGrs3094893231817887.24E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
777966572rs2691546GArs2691546217900081.38E-06Bronchial asthma in combination with atopic dermatitis and/or allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractAMAGI2
777966572rs2691546GArs2691546217900088.69E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractAMAGI2
777973456rs2075013CTrs2075013217900086.94E-06Bronchial asthma in combination with atopic dermatitis and/or allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTMAGI2
777973787rs2075014TCrs2075014217900086.74E-06Bronchial asthma in combination with atopic dermatitis and/or allergic rhinitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCMAGI2
778249167rs11770702AGrs11770702231817885.08E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
781786043rs2367910ACrs2367910227920823.40E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
788945484rs38948GArs38948217900086.79E-06Atopic sensitization in skin allergy testNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGZNF804B
791174263rs7787692CArs7787692239672691.60E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
795085431rs11770226ACrs11770226201592424.69E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
797423394rs1229540GArs1229540pha0031285.35E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANANANANA
798304764rs13223648CTrs13223648237067090.0000021NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
7100457356rs314376AGrs314376235170422.50E-05ChildrenNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
7100505792rs7803865AGrs7803865235170424.20E-05ChildrenNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
7100512824rs13232524CTrs13232524235170425.30E-05ChildrenNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
7105658451rs6967330GArs6967330219078643.20E-06NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
7105658451rs6967330GArs6967330242415373.00E-14NA1.26[1.18-1.33] 1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6967330-ANAACDHR3
7106594885rs7779057CTrs7779057226949300.0000111NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
7108201328rs2240449CArs2240449231817881.15E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7109262114rs10261639TGrs10261639239672699.26E-05NA1.38[1.38-2.63]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10261639-GResearch Support, Non-U.S. Gov'tTNA
7110677656rs6958325AGrs6958325201592422.33E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
7116917118rs4730775CTrs4730775217328293.00E-08NA1.2[1.14-1.30] 856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseaseNAResearch Support, Non-U.S. Gov'tCWNT2
7125036538rs12533496CTrs12533496231817885.76E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7125088151rs1526413AGrs1526413231817881.20E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
7130875552rs326234GArs326234201592425.12E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
7131021099rs7807274GArs7807274238296864.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralAMKLN1
7134845432rs3250GArs3250213592104.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tT
7136483470rs7792231TCrs7792231213592101.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tC
7154058474rs12536378CTrs12536378239672691.30E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
7156352856rs17837682CGrs17837682238296868.24E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCLOC100506380
7157880135rs7780849AGrs7780849217900089.00E-06Total serum IgENANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGPTPRN2
8677305rs4735916GArs4735916235413247.02E-05ppFEV10.24[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4735916-AResearch Support, N.I.H., Extramural
83417189rs11991146CGrs11991146231817881.10E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
83527234rs6998429CTrs6998429237067090.0000067NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTCSMD1
84196066rs13267437AGrs13267437206989759.50E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
88111659rs13274039AGrs13274039239672691.56E-05NA1.34[1.34-2.21]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars13274039-AResearch Support, Non-U.S. Gov'tANA
89264711rs6601306CTrs6601306247923824.00E-06NA0.34[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
89600917rs9644708TCrs9644708110220113.44E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars9644708-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC,T
89860080rs545854GCrs545854110220113.57E-07phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars545854-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
810085359rs10503404AGrs10503404231817886.46E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
810626333rs17774023TCrs17774023pha0031285.07E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATPINX1intron
811079259rs4841511TCrs4841511217900084.03E-06Atopic sensitization in skin allergy testNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
813058674rs2016444CGrs2016444243154511.00E-12(EA)0.29[0.21-0.37] unit decrease5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2016444-GMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
813058674rs2016444CGrs2016444243154519.00E-07NA0.13[0.079-0.181] unit decrease5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
817322180rs2705044GTrs2705044235413247.46E-05FEV1/FVC ratio0.21[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2705044-AResearch Support, N.I.H., Extramural
826280472rs4871977AGrs4871977237067090.0000084NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
827319905rs11778371CTrs11778371194269558.10E-07NANANA422 cases; 1,533 controlsNOPOP(1955)ALL(1955)NOPOP(1955)ALL(1955)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
827319905rs11778371CTrs11778371206989757.92E-07AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
828069928rs12543257ACrs12543257pha0031275.50E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
830447818rs2979520CGrs2979520225027970.000688NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
832607874rs4512342TGrs4512342176114962.00E-09NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
834045261rs9297216CA,G,Trs9297216238296861.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
836994665rs576778TArs576778231817881.21E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
837209300rs11785595CTrs11785595110220115.22E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars11785595-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
854119214rs1425902GArs1425902239672691.00E-06NA2.14[1.56-2.94]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1425902-GResearch Support, Non-U.S. Gov'tGNA
869992380rs2912522GArs2912522217328292.00E-13NA1.39[1.28-1.52]856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseaseNAResearch Support, Non-U.S. Gov'tALOC100505718
870442828rs7836170TCrs7836170235413242.15E-05ppFEV10.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7836170-TResearch Support, N.I.H., Extramural
870442828rs7836170TCrs7836170235413249.77E-05ppFVC0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7836170-TResearch Support, N.I.H., Extramural
870484161rs17646998CTrs17646998235413243.61E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars17646998-TResearch Support, N.I.H., Extramural
881120189rs4415363CTrs4415363226949300.0000321NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
881126925rs7814057ACrs7814057226949300.0000644NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
883889759rs7006993CTrs7006993238296863.06E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
895176015rs11776675TCrs11776675219078642.70E-06NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
896599566rs3104961CTrs3104961217900089.58E-06Atopic dermatitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGLOC100616530
896609971rs3134236AGrs3134236217900089.58E-06Atopic dermatitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCLOC100616530
896625550rs3134211CTrs3134211217900089.58E-06Atopic dermatitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGLOC100616530
898389164rs2853288GArs2853288231817881.33E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8101137897rs2453626TCrs2453626218045492.82E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
8105811365rs1460239CTrs1460239217900081.00E-06Metacholine concentration in bronchial challenge test (PC20)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
8107326900rs7013315AGrs7013315227920822.30E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8107331653rs12682157AGrs12682157227920821.70E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8107333828rs9297380CTrs9297380227920822.70E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8107334109rs9283944CTrs9283944227920822.80E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8107334331rs9297381GArs9297381227920822.80E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8107334686rs2345581AGrs2345581227920822.80E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8107335570rs10105383ATrs10105383227920822.90E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8107336888rs9774587CArs9774587227920823.80E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
8107336940rs16874388TCrs16874388227920825.50E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
8107339141rs10092617AGrs10092617227920827.30E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8107353313rs6992673GArs6992673227920827.00E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8107353858rs10283328GArs10283328227920826.90E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8108377901rs2163870AGrs2163870243154513.00E-06NA0.06[0.033-0.081] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
8108377901rs2163870AGrs2163870243154515.24E-05(EA)0.06[0.03-0.09] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2163870-GMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
8109228008rs611744AGrs611744217328298.00E-15NA1.33[1.23-1.43]856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseaseNAResearch Support, Non-U.S. Gov'tCEIF3E
8114885432rs6469488GArs6469488242801047.00E-06NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6469488-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8118025645rs3019885TGrs3019885218145175.00E-13NA1.34[1.24-1.45]938 Japanese ancestry cases; 2,376 Japanese ancestry controlsJapanese(3314)ALL(3314)ASN(3314)ALL(3314)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3019885-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8119152919rs2451167CArs2451167238296862.07E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
8123354335rs12056619AGrs12056619237067090.0000028NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
8124951527rs4870880AGrs4870880225615313.25E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8126540051rs1551398GArs1551398211508785.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
8126789900rs1036966CTrs1036966238296865.93E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
8127343692rs10101575TCrs10101575231817881.01E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
8129264589rs9792269AGrs9792269211508783.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8133704712rs10097529CArs10097529227920828.80E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
8135986892rs7465467GArs7465467226949300.00000796NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8139884509rs6988229CTrs6988229235082669.00E-06Recessive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars6988229-TResearch Support, N.I.H., ExtramuralTCOL22A1
8143298768rs7835585GTrs7835585238296869.49E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTTSNARE1
9678010rs16922480AGrs16922480238296865.02E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralAKANK1
9986085rs279880AGrs279880231817888.28E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
91202371rs10809650AGrs10809650217328296.00E-09NA1.25[1.14-1.35] 856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseaseNAResearch Support, Non-U.S. Gov'tANA
93946659rs10491899TCrs10491899110220111.52E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10491899-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
94981602rs10758669CArs10758669211508783.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
96078614rs371454CTrs371454208605033.62E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
96108921rs340900TCrs340900231817885.14E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
96128897rs340908TCrs340908208605032.81E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
96128897rs340908TCrs340908219078643.20E-07NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
96188652rs1412426AC,G,Trs1412426208605031.82E-09NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
96190076rs1342326ACrs1342326208605039.00E-10NA1.2[1.13-1.28]10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1342326-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
96190076rs1342326ACrs1342326219078649.20E-10NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
96190076rs1342326ACrs1342326225615319.20E-10NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
96190076rs1342326ACrs1342326242415371.10E-10NA1.53[1.35-1.73]1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1342326-CNATNA
96193455rs2381416CArs2381416218045492.00E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
96197392rs1888909TCrs1888909218045493.97E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
96209697rs992969AGrs992969208605034.81E-13NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
96210099rs3939286TCrs3939286208605034.11E-13NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
96213387rs928413GArs928413208605032.17E-13NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
96213387rs928413GArs928413242415379.00E-13NA1.24[1.17-1.32] 1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars928413-GNAANA
96219176rs2066362GTrs2066362208605039.03E-12NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
96237547rs17498196ACrs17498196208605035.06E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
97391855rs10120589GArs10120589238296869.55E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
910354770rs16925863TCrs16925863pha0031281.78E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATPTPRDintron
912521826rs16929097GArs16929097238296868.00E-09NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
914524438rs927969CArs927969pha0031283.99E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
916816755rs3936215CTrs3936215244060738.60E-07NA1.38[1.21-1.56]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
917070633rs2774633AGrs2774633226949300.000043NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
917071162rs2129626ACrs2129626226949300.0000246NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
917377629rs13285126CArs13285126226949300.000086NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
919579427rs3780215GArs3780215235170427.00E-06adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
920098711rs16937883AGrs16937883191873327.00E-06NA5.29[2.41-11.61] 84 Korean ancestry cases; 263 Korean ancestry controlsKorean(347)ALL(347)ASN(347)ALL(347)Asthma (toluene diisocyanate-induced)HPOID:0002099AsthmaDOID:2841asthmaD059366Asthma, OccupationalNANAAsthmars16937883-GResearch Support, Non-U.S. Gov'tANA
932348024rs10511905AGrs10511905235082663.00E-04Additive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars10511905-GResearch Support, N.I.H., ExtramuralANA
932433526rs10970976TCrs10970976225615314.00E-06NA1.28[1.16-1.43] 933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
933113970rs12379501CTrs12379501pha0031274.77E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATB4GALT1intron
933115556rs2183124AGrs2183124pha0031273.86E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAAB4GALT1intron
935700837rs4879926CTrs4879926239672698.00E-06NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTTLN1
971618245rs10781329GArs10781329110220118.34E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10781329-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
973491479rs11787887ATrs11787887231817885.10E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
973655072rs1411164ACrs1411164201592424.46E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
975792301rs10781126AGrs10781126227920824.40E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
975810393rs4581121CTrs4581121227920821.80E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
975813310rs7874116ACrs7874116227920823.70E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
981926265rs7045156TCrs7045156238296865.73E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
982039362rs2378383AGrs2378383197142057.00E-07NA1.64[1.32-2.04] 492 Mexican triosMexican(492)ALL(492)HIS(492)ALL(492)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
984144714rs11139298ACrs11139298pha0031283.96E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
987065048rs6559804CGrs6559804225027970.000347NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
988398905rs7048878CTrs7048878110220119.89E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7048878-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
989527458rs11141597AGrs11141597238296862.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
9101295417rs12351127CTrs12351127110220114.09E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars12351127-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
9104636695rs1415649CTrs1415649238296862.69E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
9105797832rs10820351GTrs10820351231817881.56E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
9109247001rs16925517GArs16925517238296861.90E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
9109546063rs10759199GCrs10759199110220119.45E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10759199-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
9110787096rs7868720CTrs7868720110220119.47E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7868720-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
9111403445rs10122628AGrs10122628237067090.000005NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
9116742214rs12682865TCrs12682865230408850.00000022NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
9116749530rs4979311GCrs4979311230408850.00000061NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
9117566440rs4263839AGrs4263839211508783.00E-10NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
9119843051rs1889318TCrs1889318227920823.20E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
9119850813rs1334086GArs1334086227920824.20E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
9123652898rs881375TCrs881375219078644.00E-08NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
9123948375rs10760153TCrs10760153213592104.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tT
9128748401rs10987080GArs10987080206989754.10E-05AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
9131048760rs2240956TCrs2240956231817885.25E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
9133534279rs3802344GArs3802344243154512.14E-05(EA)0.13[0.07-0.19] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3802344-AMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
9133534279rs3802344GArs3802344243154515.00E-06NA0.11[0.064-0.158] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
9135724901rs2771994TCrs2771994231802726.05E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tGAK8
9135767943rs1050700CTrs1050700231802721.12E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tATSC1
9135774164rs11243929TCrs11243929231802722.35E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCTSC1
9135776341rs7020438CArs7020438231802722.07E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tATSC1
9135778827rs10901219CTrs10901219231802722.09E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCTSC1
9135779530rs12345576TCrs12345576231802722.01E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCTSC1
9135781563rs10901220GArs10901220231802722.01E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tGTSC1
9135786904rs1073123AGrs1073123231802722.06E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tGTSC1
9135813001rs7874234CTrs7874234231802726.70E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCTSC1
103964161rs11252191CTrs11252191244060731.30E-07NA1.54[1.31-1.80]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
103968713rs7086533ACrs7086533244060733.80E-07NA1.51[1.29-1.77]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
104240870rs11252394GArs11252394227920824.30E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
104240870rs11252394GArs11252394235082662.00E-07Additive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars11252394-AResearch Support, N.I.H., ExtramuralGNA
104758118rs17133449TCrs17133449217900084.00E-06Lung function, maximal expiration flow at 75% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTNA
106572225rs11259403CTrs11259403235170427.00E-06adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
108367870rs1538246ACrs1538246pha0031284.18E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
108926700rs1444774GArs1444774218045489.64E-04NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
108958587rs11255975TCrs11255975236662770.000849NANANA745 African American cases; 3238 African American controlsAfrican American(3983)ALL(3983)AFR(3983)ALL(3983)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
108972018rs10508372GArs10508372218045482.00E-15NA1.16[1.12-1.21]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10508372-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
109013198rs10430791TCrs10430791218045486.12E-05NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1012869000rs1644392AGrs1644392237067090.00008NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tACAMK1D
1012882041rs1644412CTrs1644412237067090.000037NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
1013777194rs7900357GArs7900357239672693.58E-05NA1.39[1.39-2.63]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7900357-GResearch Support, Non-U.S. Gov'tGFRMD4A
1014488967rs7905868TCrs7905868239672696.64E-05NA1.36[1.36-2.46]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7905868-CResearch Support, Non-U.S. Gov'tTNA
1016138489rs11253779CTrs11253779235413243.36E-05ppFEV10.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars11253779-TResearch Support, N.I.H., Extramural
1016145787rs7098374TCrs7098374235413245.11E-05ppFEV10.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7098374-TResearch Support, N.I.H., Extramural
1016158880rs10795348CTrs10795348235413245.07E-05ppFEV10.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars10795348-TResearch Support, N.I.H., Extramural
1020229749rs6482071TCrs6482071235413246.50E-05ppFVC0.31[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars6482071-TResearch Support, N.I.H., Extramural
1022205676rs2666781CArs2666781176114964.00E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1030116104rs11007764CGrs11007764238296863.44E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1031611256rs7894459CTrs7894459231817887.83E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1035287650rs17582416TGrs17582416211508782.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1036637021rs11010633GTrs11010633110220115.11E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars11010633-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1038009483rs11011346CTrs11011346206989756.70E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1053493473rs7922491GArs7922491219078645.00E-07NA1.13[1.08-1.19] 12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7922491-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1053602190rs12247820AGrs12247820206989754.20E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1054765608rs2249003ACrs2249003pha0031272.70E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
1056208967rs1930149TCrs1930149239672698.75E-05NA1.29[1.29-2.17]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1930149-GResearch Support, Non-U.S. Gov'tGPCDH15
1056517410rs10763141AGrs10763141235413244.71E-05ppFEV10.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars10763141-AResearch Support, N.I.H., Extramural
1059146466rs2928442TCrs2928442238296868.68E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1064438486rs10995271GCrs10995271211508784.00E-20NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1064470675rs224136CTrs224136219078641.00E-10NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1068088508rs10762058CGrs10762058191873326.00E-06NA5[2.36-10.60] 84 Korean ancestry cases; 263 Korean ancestry controlsKorean(347)ALL(347)ASN(347)ALL(347)Asthma (toluene diisocyanate-induced)HPOID:0002099AsthmaDOID:2841asthmaD059366Asthma, OccupationalNANAAsthmars10762058-GResearch Support, Non-U.S. Gov'tGCTNNA3
1072515691rs946742CArs946742226949300.0000178NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1072517206rs2791189TCrs2791189226949300.000000456NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1072520930rs2541232GArs2541232226949300.0000859NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1073591530rs11000019GArs11000019238296868.00E-08NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGPSAP
1078106937rs17450685CTrs17450685235413248.73E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars17450685-TResearch Support, N.I.H., Extramural
1081058027rs1250552AGrs1250552211508789.00E-10NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1083835232rs11192402CArs11192402217900087.00E-06Lung function, maximal expiration flow at 75% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNRG3
1084051375rs2225809GArs2225809pha0031288.18E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANRG3intron
1084206002rs7909484CTrs7909484pha0031284.94E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNRG3intron
1091643607rs1324705CTrs1324705184015940.00009NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
1094839642rs2068888GArs2068888225615312.12E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1098556785rs6584099ATrs6584099110220114.33E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars6584099-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
10100855702rs12570188CTrs12570188238296865.00E-08NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCHPSE2
10101291593rs11190140TCrs11190140211508783.00E-16NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
10108334189rs12359404CTrs12359404238296863.10E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCSORCS1
10115018340rs4265536TCrs4265536110220118.64E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars4265536-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
10116281550rs2497708ACrs2497708239672691.00E-04NA1.29[1.29-2.18]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2497708-AResearch Support, Non-U.S. Gov'tCABLIM1
10116292561rs2497714AGrs2497714235413244.66E-05ppFVC0.33[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2497714-AResearch Support, N.I.H., Extramural
10116604344rs2181563TCrs2181563235413246.72E-05ppFVC0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2181563-AResearch Support, N.I.H., Extramural
10116908479rs1314595TCrs1314595238296866.91E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralAATRNL1
10119227342rs4752066GTrs4752066235413246.00E-07ppFEV10.3[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4752066-TResearch Support, N.I.H., Extramural
10119234786rs242966TCrs242966235413248.02E-06ppFEV10.25[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars242966-AResearch Support, N.I.H., Extramural
10119647256rs17642749TGrs17642749248242164.00E-07(African American/African Caribbean, male)2.97[1.90-4.63] 1,052 European ancestry male cases; 1,019 European ancestry female cases; 709 European ancestry male controls; 826 European ancestry female controls; 675 African ancestry male cases; 837 African ancestry female cases; 577 African ancestry male controls; 926 African ancestry female controls; 926 Latino male cases; 710 Latino female cases; 410 Latino male controls; 382 Latino female controlsAfrican(3015)European(3606)Latino(2428)ALL(9049)HIS(2428)AFR(3015)EUR(3606)ALL(9049)Asthma (sex interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
10120463720rs10886289GTrs10886289110220116.41E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10886289-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
10120909785rs11198804CTrs11198804225027970.000194NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
10121881681rs928382CGrs928382238296863.19E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
10123092807rs4752536AGrs4752536235413241.06E-05ppFVC0.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4752536-AResearch Support, N.I.H., Extramural
10123094861rs11199916ACrs11199916235413241.37E-05ppFVC0.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars11199916-AResearch Support, N.I.H., Extramural
10124120457rs10510109GTrs10510109225027970.000649NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG,T
10124138804rs10749466AGrs10749466225027970.00016NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
10124145212rs7068487CTrs7068487225027970.000275NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
10124149352rs7088058CTrs7088058225027970.000177NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
10124167004rs10887149GArs10887149225027970.000888NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
10124167512rs2421016CTrs2421016225027970.00000356NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
10124192430rs10510110TCrs10510110225027970.0000517NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
10124193181rs2280141TGrs2280141225027970.0000461NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
10126911566rs17152730TCrs17152730238296862.52E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
10130573275rs1327013AGrs1327013238296865.90E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
10132509961rs7908624CTrs7908624238296864.47E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
111101649rs7480563TCrs7480563225615314.68E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
112616053rs10400286TCrs10400286238296863.44E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTKCNQ1
115085254rs16909520CTrs16909520201592423.81E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1111918698rs4360694TCrs4360694235413243.73E-05ppFVC0.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4360694-TResearch Support, N.I.H., Extramural
1111922325rs4910031TCrs4910031235413244.54E-05ppFVC0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4910031-TResearch Support, N.I.H., Extramural
1112245343rs6485587TCrs6485587pha0031278.10E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATMICAL2intron
1117429872rs4148634GArs4148634235413243.48E-05ppFEV10.26[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4148634-TResearch Support, N.I.H., Extramural
1117433088rs7926934ACrs7926934235413242.64E-05ppFEV10.26[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7926934-AResearch Support, N.I.H., Extramural
1119100736rs10766527GArs10766527226949300.000071NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1119106045rs11024979CTrs11024979226949300.0000454NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1119108683rs16936115TCrs16936115226949300.0000679NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1119541784rs2632057TCrs2632057pha0031279.52E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNAV2intron
1119546520rs2702646TGrs2702646226949300.0000525NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1119546842rs2702628CTrs2702628226949300.0000524NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1120050143rs920672AGrs920672238296865.79E-08NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANAV2
1120654585rs12283302GTrs12283302239672698.15E-05NA1.35[1.35-2.56]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12283302-TResearch Support, Non-U.S. Gov'tGSLC6A5
1122200763rs10833711GArs10833711pha0031273.98E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
1123192015rs16910754CTrs16910754231817882.77E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1123192235rs17306398AC,G,Trs17306398231817881.62E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1126895905rs4431984CTrs4431984110220114.62E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars4431984-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1127443151rs4448642TCrs4448642226949300.0000356NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1133475831rs10836063CTrs10836063239672691.10E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
1134806466rs11032873TCrs11032873235413243.08E-05FEV1/FVC ratio0.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars11032873-TResearch Support, N.I.H., Extramural
1135593885rs1348879GArs1348879227920824.90E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1135886919rs684909TCrs684909206989753.12E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1137396461rs1822933AGrs1822933235413249.49E-05ppFVC0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1822933-AResearch Support, N.I.H., Extramural
1137439348rs1822934AGrs1822934235413249.35E-05ppFVC0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1822934-AResearch Support, N.I.H., Extramural
1139754355rs1702585GArs1702585231817889.70E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1140212151rs10734479GTrs10734479pha0031283.66E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATLRRC4Cintron
1143553927rs11037466AGrs11037466110220112.87E-06phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars11037466-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1144607471rs1981993GArs1981993238296869.55E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralACD82
1161725498rs2668898AG,Trs2668898110220115.65E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2668898-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1163231259rs12280132TGrs12280132238296867.74E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTHRASLS5
1168680577rs10896379CTrs10896379219078644.10E-06NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1169533129rs11263535AGrs11263535239672698.04E-05NA1.44[1.44-2.97]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars11263535-GResearch Support, Non-U.S. Gov'tANA
1169553604rs7105655CArs7105655239672691.61E-05NA1.49[1.49-3.03]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7105655-CResearch Support, Non-U.S. Gov'tCNA
1172894273rs11603160CTrs11603160235170428.00E-06adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
1176270683rs7130588AGrs7130588219078642.00E-08NA1.09[1.06-1.13] 12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7130588-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1176270683rs7130588AGrs7130588231817881.10E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1176301316rs7927894CTrs7927894211508781.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1176301316rs7927894CTrs7927894231817888.81E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1176301375rs7927997CTrs7927997231817887.21E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1181754688rs678021CTrs678021110220112.95E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars678021-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1181775950rs2851687TC,Grs2851687110220112.83E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2851687-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1181804571rs480213AGrs480213110220112.69E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars480213-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1182041847rs2175961TCrs2175961184015940.00006NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
1188286437rs10128616GCrs10128616238296866.03E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCGRM5
1195003263rs11021111CGrs11021111238296867.98E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1196841814rs17275283TCrs17275283201592422.30E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1197624373rs1039951GArs1039951217900085.00E-06Metacholine concentration in bronchial challenge test (PC20)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
1198474723rs10892026GArs10892026235413249.83E-05ppFEV10.14[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars10892026-AResearch Support, N.I.H., Extramural
1198483202rs7102022AGrs7102022235413243.29E-05ppFEV10.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7102022-AResearch Support, N.I.H., Extramural
11104812647rs674467CTrs674467238296862.38E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
11107566585rs597872TCrs597872225615313.08E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
11107825239rs10890784GArs10890784110220111.84E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars10890784-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA,G
11112546305rs7113799TCrs7113799226949300.0000138NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
11114231255rs11214966TCrs11214966218045496.00E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
11115487740rs2846895CTrs2846895239672692.93E-05NA1.36[1.36-2.37]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2846895-AResearch Support, Non-U.S. Gov'tGNA
11115487952rs2613468GArs2613468239672693.39E-05NA1.34[1.34-2.28]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2613468-AResearch Support, Non-U.S. Gov'tGNA
11115498833rs2155633CTrs2155633239672692.91E-05NA1.35[1.35-2.31]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2155633-AResearch Support, Non-U.S. Gov'tANA
11115501794rs2155631ACrs2155631239672694.89E-05NA1.32[1.32-2.27]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2155631-GResearch Support, Non-U.S. Gov'tGNA
11115515326rs1785016CTrs1785016239672693.64E-05NA1.35[1.35-2.36]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1785016-AResearch Support, Non-U.S. Gov'tANA
11115521706rs1698157CArs1698157239672691.30E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
11115521706rs1698157CArs1698157239672694.49E-05NA1.32[1.32-2.26]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1698157-AResearch Support, Non-U.S. Gov'tANA
11123167298rs6589994TArs6589994213592106.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tT
11123648333rs17744026TGrs17744026239672693.00E-06NA4[2.08-7.69]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars17744026-TResearch Support, Non-U.S. Gov'tTNA
11123686185rs11219307GTrs11219307239672691.90E-05NA1.54[1.54-3.45]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars11219307-GResearch Support, Non-U.S. Gov'tGNA
11123687286rs2155362GArs2155362239672691.90E-05NA1.54[1.54-3.45]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2155362-GResearch Support, Non-U.S. Gov'tANA
11123716249rs1939915TCrs1939915239672698.80E-05NA1.39[1.39-2.78]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1939915-TResearch Support, Non-U.S. Gov'tTNA
11123717248rs2155363TCrs2155363239672698.80E-05NA1.39[1.39-2.78]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2155363-TResearch Support, Non-U.S. Gov'tCNA
11123723946rs12283877CTrs12283877239672693.88E-05NA1.49[1.49-3.33]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12283877-CResearch Support, Non-U.S. Gov'tCNA
11123742913rs12273131CTrs12273131239672693.14E-05NA1.49[1.49-3.33]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12273131-CResearch Support, Non-U.S. Gov'tCNA
11127156732rs2322732AGrs2322732239672696.07E-05NA1.49[1.49-3.45]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2322732-GResearch Support, Non-U.S. Gov'tGNA
11127761666rs7927044GArs7927044225604797.00E-09NA0.16[NA] unit decrease573 European ancestry childrenEuropean(573)ALL(573)EUR(573)ALL(573)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmars7927044-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
11128380974rs11221332CTrs11221332211508785.00E-16NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
11129263154rs10791006TCrs10791006239672692.45E-05NA1.35[1.35-2.33]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10791006-CResearch Support, Non-U.S. Gov'tTBARX2
11129327691rs984176AGrs984176230408850.0000028NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
11129650451rs1940108TCrs1940108231817881.94E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
11129657216rs10791048CArs10791048231817887.03E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
11131520368rs1857922TCrs1857922227920824.00E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
11134172031rs1144219GTrs1144219231817885.57E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
122205886rs7298821TCrs7298821239672691.30E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCCACNA1C
122749127rs216026TGrs216026243154511.43E-04(EA)0.07[0.03-0.1] unit decrease5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars216026-TMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
122749127rs216026TGrs216026243154518.00E-06NA0.07[0.038-0.096] unit decrease5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
125355373rs7302032GArs7302032110220114.99E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7302032-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
126488450rs11064153TCrs11064153110220115.39E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars11064153-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1212902272rs12318822TGrs12318822226949300.000036NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1213859584rs17220663GArs17220663pha0031279.30E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGGRIN2Bintron
1214760028rs11831626TCrs11831626237067090.0000095NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
1214775260rs11836172GArs11836172237067090.0000095NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGGUCY2C
1220313437rs1427988ACrs1427988226949300.0000292NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1221731522rs11046127CTrs11046127231817881.02E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1222198865rs2955503GArs2955503226949300.0000334NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1223981788rs9804956CTrs9804956231817883.12E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1225993804rs16929496TCrs16929496218045492.60E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1226022138rs11048311ACrs11048311218045494.70E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1226028407rs11048317TGrs11048317218045493.32E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1230097843rs7958129GTrs7958129227920821.80E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1240601940rs11175593CTrs11175593211508783.00E-10NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1241893994rs17129414AGrs17129414238296861.57E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralAPDZRN4
1252266348rs1566869GArs1566869239672692.12E-05NA1.38[1.38-2.43]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1566869-GResearch Support, Non-U.S. Gov'tA,GNA
1252266348rs1566869GArs1566869239672699.05E-05NA1.29[1.29-2.19]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1566869-GResearch Support, Non-U.S. Gov'tA,GNA
1252660812rs2852474GArs2852474239672693.80E-05NA1.47[1.47-3.23]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2852474-GResearch Support, Non-U.S. Gov'tGNA
1252935247rs609704CTrs609704239672698.96E-05NA1.31[1.31-2.28]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars609704-CResearch Support, Non-U.S. Gov'tTNA
1256364321rs2069408AGrs2069408218045481.00E-10NA1.15[1.10-1.20]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2069408-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1256365979rs2069415GArs2069415218045488.07E-05NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1256374695rs773109GArs773109218045482.56E-05NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1256401085rs10876864GArs10876864218045482.70E-06NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1256412487rs1701704TGrs1701704218045482.00E-13NA1.19[1.14-1.25]1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1701704-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1256478658rs7971751ACrs7971751218045483.29E-06NANANA1,532 Japanese ancestry cases; 3,304 Japanese ancestry controlsJapanese(4836)ALL(4836)ASN(4836)ALL(4836)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1261672165rs7963956TGrs7963956210722014.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
1263392391rs12826619GCrs12826619231817881.05E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1266556960rs1168745GArs1168745239672696.21E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTTMBIM4
1269305458rs1152937TCrs1152937239672694.45E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCCPM
1271255025rs4294640TGrs4294640239672699.00E-05NA1.32[1.32-2.32]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4294640-TResearch Support, Non-U.S. Gov'tGPTPRR
1274445607rs7305291CTrs7305291227920821.80E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1274462370rs12824038GArs12824038227920825.50E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1274465532rs11179902CArs11179902227920825.50E-06NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1274505531rs11179922TCrs11179922227920822.10E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1274522056rs12306576AGrs12306576227920821.30E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1274528830rs11179933CTrs11179933227920822.50E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1278851869rs10506786GArs10506786pha0031275.59E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
1279109021rs10219720ATrs10219720238296869.10E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralANA
1279291372rs1551847ACrs1551847237067090.0000022NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTSYT1
1282325768rs6539603TCrs6539603pha0031273.51E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
1282400181rs1529757CTrs1529757226949300.0000451NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1294361527rs4146626GArs4146626227920829.60E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1294500590rs7308292GArs7308292235413244.67E-05ppFVC0.2[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7308292-AResearch Support, N.I.H., Extramural
1294502584rs17231818TCrs17231818235413243.94E-05ppFVC0.23[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars17231818-TResearch Support, N.I.H., Extramural
1296634205rs11835157AGrs11835157247923826.00E-06NA0.32[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tAELK3
1297676235rs1558726GArs1558726244860691.02E-05NA0.36[NA] unit increase124 European ancestry individualsEuropean(124)ALL(124)EUR(124)ALL(124)Asthma (corticosteroid response)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, N.I.H., ExtramuralGNA
12107956249rs182722816GTrs182722816244060737.00E-07NA5.7[2.86-11.34]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
12108371313rs7974135GArs7974135238296861.90E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
12112007756rs653178CTrs653178211508787.00E-21NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
12116035167rs2195003AGrs2195003239672696.11E-05NA1.35[1.35-2.44]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2195003-AResearch Support, Non-U.S. Gov'tGNA
12116749737rs10850603TCrs10850603226949300.00000189NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
12122676013rs11060167ACrs11060167210722014.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGLRRC43
12125316770rs7967521TCrs7967521239672691.40E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCSCARB1
12125991984rs4765045AGrs4765045231817882.06E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
12127656553rs10773370CTrs10773370239672698.26E-05NA1.31[1.31-2.30]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10773370-TResearch Support, Non-U.S. Gov'tCNA
12128494033rs4761051GArs4761051239672692.68E-05NA1.34[1.34-2.25]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4761051-AResearch Support, Non-U.S. Gov'tGNA
12128719362rs11612995CTrs11612995237067090.0000005NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
12128729838rs7970358AGrs7970358237067090.0000033NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
12129675423rs12422767CTrs12422767226949300.0000865NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
12129711446rs12371373GArs12371373110220117.18E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars12371373-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG,A
12130038858rs4759966CA,Grs4759966110220113.10E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars4759966-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
12131939920rs10466868GTrs10466868235413246.39E-05ppFVC0.25[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars10466868-TResearch Support, N.I.H., Extramural
1319658933rs9581191CTrs9581191226949300.0000213NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1319798532rs2765209CTrs2765209pha0031283.69E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
1323200009rs41334648GArs41334648238296868.24E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1323231920rs9552679TCrs9552679235082663.02E-05Additive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars9552679-CResearch Support, N.I.H., ExtramuralTNA
1325861577rs3809335AGrs3809335235413245.40E-05FEV1/FVC ratio0.28[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars3809335-TResearch Support, N.I.H., Extramural
1327415673rs9319321ATrs9319321191873323.00E-06NA5.2[2.47-10.92] 84 Korean ancestry cases; 263 Korean ancestry controlsKorean(347)ALL(347)ASN(347)ALL(347)Asthma (toluene diisocyanate-induced)HPOID:0002099AsthmaDOID:2841asthmaD059366Asthma, OccupationalNANAAsthmars9319321-TResearch Support, Non-U.S. Gov'tTNA
1327469768rs17084857TCrs17084857110220117.67E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars17084857-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1329813633rs1999716TGrs1999716pha0031286.04E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAAMTUS2intron
1330916263rs12429252AGrs12429252243154514.00E-06NA0.12[0.068-0.166] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
1333798262rs2555603ACrs2555603235170423.00E-06adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
1333825641rs2555595TCrs2555595235170421.30E-05adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
1336351766rs7328278ACrs7328278225604793.00E-06NA0.13[NA] unit increase573 European ancestry childrenEuropean(573)ALL(573)EUR(573)ALL(573)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmars7328278-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1338484529rs817737CTrs817737184015940.0003NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
1338511215rs1337604CTrs1337604184015940.00028NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
1338927888rs2150468TGrs2150468184015940.00009NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
1341610561rs2031662CTrs2031662238296864.30E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
1342073812rs1105145CTrs1105145225027970.000172NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1344457925rs3764147AGrs3764147211508782.00E-13NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1349250997rs1323555GArs1323555247923822.00E-06NA0.34[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
1358988271rs7988007ACrs7988007110220116.28E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7988007-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1359245163rs1537473GCrs1537473110220117.53E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1537473-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1359246294rs9569918TCrs9569918110220117.11E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars9569918-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tT
1359797726rs13378924TCrs13378924230408850.0000013NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1359811662rs9538344TGrs9538344230408850.0000015NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1359814259rs9538345TCrs9538345230408850.0000012NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1359815206rs9538346AGrs9538346230408850.0000033NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1359819143rs9570077TCrs9570077230408850.000000099NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1363638329rs3119939TCrs3119939219078648.00E-06NA1.08[1.04-1.10] 12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1363679702rs1413065CTrs1413065225027970.000435NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1364210398rs4884502AGrs4884502247923829.00E-06NA0.32[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
1364215667rs2590931CTrs2590931247923829.44E-06NA0.32[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
1371421801rs10467606TGrs10467606226949300.0000127NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1371421801rs10467606TGrs10467606pha0031273.11E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
1377547791rs679090CTrs679090184015940.00003NANANA96 Puerto Rican cases; 88 Puerto Rican controlsNOPOP(184)ALL(184)NOPOP(184)ALL(184)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tComparative Study
1379834482rs9574386GArs9574386235413247.72E-05FEV1/FVC ratio0.27[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars9574386-AResearch Support, N.I.H., Extramural
1381062941rs1930336TCrs1930336247923823.00E-06NA0.35[NA] unit increase189 Korean ancestry casesKorean(189)ALL(189)ASN(189)ALL(189)Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
1384030514rs9318942TCrs9318942206989758.72E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1395916201rs9590225CTrs9590225238296868.95E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCABCC4
13100086259rs4772201AGrs4772201226949300.00000866NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
13100086259rs4772201AGrs4772201pha0031274.58E-06phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
13110535092rs1414320GArs1414320225615312.33E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
13110652684rs11616866GArs11616866231817889.19E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
13112523965rs9549433CArs9549433239672697.40E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
13113284191rs9603917CTrs9603917pha0031278.37E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
13113329401rs17121478CTrs17121478pha0031271.99E-06phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACC13orf35intron
13114457173rs7330442CArs7330442226949300.0000527NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
13114476911rs7489746CTrs7489746226949300.0000858NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1420503541rs17122640GArs17122640pha0031287.72E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
1426069812rs11159411CTrs11159411239672691.50E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
1431040974rs7146136AGrs7146136pha0031276.00E-06phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAAG2E3intron
1432911026rs1957018GArs1957018pha0031281.94E-06phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAAAKAP6intron
1432919779rs6571518TCrs6571518pha0031282.27E-06phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACAKAP6intron
1433245114rs17441370CTrs17441370231817881.37E-11NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1433683746rs12586992TGrs12586992pha0031288.58E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNPAS3intron
1434690056rs6571636AGrs6571636239672698.05E-05NA1.32[1.32-2.33]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6571636-GResearch Support, Non-U.S. Gov'tANA
1437564413rs8014186TCrs8014186pha0031287.03E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATSLC25A21intron
1439690756rs1998193TGrs1998193pha0031281.15E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
1441394129rs11848229GArs11848229pha0031277.75E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
1441437036rs1176974GArs1176974pha0031275.61E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
1441447041rs1901475CTrs1901475pha0031274.14E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACNANA
1441633385rs17111521CArs17111521238296864.84E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1445339443rs17115674TCrs17115674110220117.76E-06phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars17115674-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1451193213rs2984272ATrs2984272231817881.05E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1460740326rs1887104TGrs1887104239672697.34E-05NA1.67[1.67-4.42]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1887104-CResearch Support, Non-U.S. Gov'tAPPM1A
1460765245rs2273623AGrs2273623239672692.98E-05NA1.66[1.66-4.02]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2273623-GResearch Support, Non-U.S. Gov'tAPPM1A
1460765245rs2273623AGrs2273623239672693.16E-05NA1.59[1.59-3.65]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2273623-GResearch Support, Non-U.S. Gov'tAPPM1A
1466443496rs1663330AGrs1663330235082664.54E-05Additive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars1663330-GResearch Support, N.I.H., ExtramuralCNA
1466444344rs1663332CTrs1663332235082668.07E-05Additive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars1663332-TResearch Support, N.I.H., ExtramuralCNA
1471716231rs976044CTrs976044pha0031284.06E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAAC14orf56intron
1473393246rs3213729GCrs3213729210722011.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCDCAF4
1473489268rs3742829CTrs3742829231802726.73E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tAZFYVE1
1473493195rs12432987ACrs12432987231802727.02E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCZFYVE1
1473530678rs8005215TCrs8005215231802721.11E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tT,CRBM25
1478625653rs7144274GArs7144274201592429.94E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1480383025rs1534837GArs1534837206989756.50E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1481442055rs179260TCrs179260231817886.55E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1487320278rs10498606CArs10498606239672698.56E-05NA1.28[1.28-2.11]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10498606-AResearch Support, Non-U.S. Gov'tANA
1488472595rs8005161CTrs8005161219078644.00E-18NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1490758891rs2282032GTrs2282032110220111.19E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2282032-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1492421275rs2498828TCrs2498828pha0031272.42E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
1494160521rs943323CArs943323217900089.00E-06Lung function, forced vital capacity (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTUNC79
1497592627rs12883143TCrs12883143217900085.00E-06Metacholine concentration in bronchial challenge test (PC20)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTNA
1498486545rs10142119GArs10142119239672692.00E-07NA1.96[1.52-2.56]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10142119-GResearch Support, Non-U.S. Gov'tGNA
1498486545rs10142119GArs10142119239672692.86E-05NA1.37[1.37-2.38]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10142119-GResearch Support, Non-U.S. Gov'tGNA
1498488007rs1456988GTrs1456988239672691.11E-06NA1.44[1.44-2.40]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1456988-GResearch Support, Non-U.S. Gov'tTNA
1498497054rs12590389TCrs12590389239672692.47E-06NA1.43[1.43-2.40]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12590389-CResearch Support, Non-U.S. Gov'tTNA
14100896800rs7157695AGrs7157695238296867.74E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGWDR25
14101683461rs8020818TCrs8020818201592422.14E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
14101852207rs7494167GArs7494167239672691.50E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
1525003041rs11854309GArs11854309226949300.0000819NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1528513513rs916976AGrs916976pha0031288.17E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANACHERC2intron
1538168279rs12148658GArs12148658110220111.00E-04phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars12148658-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1540038433rs8033957TCrs8033957110220113.77E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars8033957-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1543440522rs7166467GArs7166467pha0031288.21E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGTMEM62intron
1548529940rs11633336AGrs11633336217900085.00E-06Lung function, maximal expiration flow at 50% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractASLC12A1
1551969668rs17525472TCrs17525472201592422.00E-06NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1560293714rs4775229ACrs4775229227920824.50E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1560580333rs11635176GArs11635176217900084.83E-06Atopic dermatitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
1560582457rs16942401AGrs16942401217900083.36E-06Atopic dermatitisNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
1561069988rs11071559CTrs11071559208605031.00E-07NA1.18[1.11-1.25] 10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars11071559-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1561069988rs11071559CTrs11071559219078641.10E-07NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1561069988rs11071559CTrs11071559225615311.10E-07NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1566159227rs12594238TCrs12594238244060733.00E-06NA1.37[1.20-1.37]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1567446785rs744910GArs744910208605034.00E-09NA1.12[1.09-1.16] 10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars744910-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1567446785rs744910GArs744910219078643.90E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1567446785rs744910GArs744910225615313.90E-09NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1567467541rs12708492TCrs12708492208605038.12E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1568155710rs4776381AGrs4776381239672691.54E-05NA1.56[1.56-3.28]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4776381-AResearch Support, Non-U.S. Gov'tGNA
1568155710rs4776381AGrs4776381239672694.92E-05NA1.52[1.52-3.28]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4776381-AResearch Support, Non-U.S. Gov'tGNA
1574092777rs8030494CArs8030494235413247.83E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars8030494-AResearch Support, N.I.H., Extramural
1579979443rs16971243AGrs16971243213592109.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tA
1586167386rs6496137ACrs6496137239672696.39E-05NA1.3[1.30-2.22]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6496137-AResearch Support, Non-U.S. Gov'tAAKAP13
1586205189rs338544AGrs338544239672691.10E-04NA1.28[1.28-2.17]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars338544-TResearch Support, Non-U.S. Gov'tTAKAP13
1589245239rs4932194ACrs4932194217328298.00E-07NA1.22[1.12-1.30] 856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseaseNAResearch Support, Non-U.S. Gov'tA,CNA
1594048638rs7170834GTrs7170834239672691.20E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
1595471060rs6496069CTrs6496069235413243.54E-05ppFVC0.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars6496069-TResearch Support, N.I.H., Extramural
1595487052rs12437784AGrs12437784235413241.01E-05ppFVC0.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars12437784-AResearch Support, N.I.H., Extramural
1599834662rs8039009CTrs8039009239672691.00E-04NA1.51[1.51-3.50]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars8039009-TResearch Support, Non-U.S. Gov'tCLRRC28
16875402rs689439TCrs689439235413247.39E-05FEV1/FVC ratio0.14[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars689439-AResearch Support, N.I.H., Extramural
16885032rs556179AGrs556179235413245.43E-05FEV1/FVC ratio0.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars556179-AResearch Support, N.I.H., Extramural
16895079rs561553ACrs561553235413247.11E-05ppFEV10.15[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars561553-AResearch Support, N.I.H., Extramural
16897566rs4984698GArs4984698235413245.74E-05FEV1/FVC ratio0.2[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4984698-AResearch Support, N.I.H., Extramural
16897566rs4984698GArs4984698235413248.33E-05ppFEV10.19[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars4984698-AResearch Support, N.I.H., Extramural
163405986rs1218762GArs1218762239672694.95E-05NA1.45[1.45-3.03]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1218762-GResearch Support, Non-U.S. Gov'tGOR2C1
163411855rs7196196CArs7196196239672696.92E-05NA1.33[1.33-2.44]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7196196-AResearch Support, Non-U.S. Gov'tCNA
163412861rs7188903AGrs7188903239672695.01E-05NA1.45[1.45-3.03]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7188903-GResearch Support, Non-U.S. Gov'tGNA
164033436rs2230739TCrs2230739235413246.25E-05FEV1/FVC ratio0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2230739-AResearch Support, N.I.H., Extramural
164766597rs17137208ACrs17137208217900086.00E-06Total serum IgENANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractAANKS3
165900889rs6500728TCrs6500728235413247.15E-05ppFVC0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars6500728-TResearch Support, N.I.H., Extramural
165952909rs1012259GArs1012259213592101.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tC
1610995850rs6498124GTrs6498124210722014.00E-05Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGCIITA
1611182893rs11642009TGrs11642009230408850.0000017NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1611219041rs12935657GArs12935657230408850.000005NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1611241906rs17673553AGrs17673553230408850.0000017NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1611403893rs12928822CTrs12928822211508783.00E-08NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1617357457rs11075345CTrs11075345231817882.09E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1619644773rs6497393AGrs6497393237067090.000034NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tAC16orf62
1622840704rs169660GArs169660235413244.20E-05ppFVC0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars169660-TResearch Support, N.I.H., Extramural
1622929129rs12599188TCrs12599188231817882.83E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1622938499rs1476458CGrs1476458231817887.12E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1625970032rs8049738TCrs8049738110220116.45E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars8049738-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1627373872rs1805011ACrs1805011237067090.00061NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tAIL4R
1631386862rs8052139CArs8052139230408850.00000032NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1649839782rs4785358GArs4785358pha0031284.14E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGZNF423intron
1650763778rs199883290GCrs2066847211508783.00E-24NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1650763778rs2066847GGCrs2066847211508783.00E-24NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1650763778rs540973741GGCrs2066847211508783.00E-24NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1650763778rs5743293GGCrs2066847211508783.00E-24NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1651820998rs16944951CTrs16944951238296864.23E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1652102937rs12931290CTrs12931290217900085.00E-06Metacholine concentration in bronchial challenge test (PC20)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCLOC388276
1654489793rs2388639CArs2388639244860699.00E-09NA0.88[NA] unit increase124 European ancestry individualsEuropean(124)ALL(124)EUR(124)ALL(124)Asthma (corticosteroid response)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1654794101rs4440156GArs4440156217900087.00E-06Lung function, maximal expiration flow at 25% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
1657967218rs247052TCrs247052206989751.80E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1660136254rs1423946GArs1423946110220111.58E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1423946-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1665938406rs12930287GArs12930287206989754.80E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1679200414rs11150140GArs11150140226949300.00000764NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1679201179rs17656178AGrs17656178226949300.00000179NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1683342234rs723919GArs723919239672691.10E-04NA1.28[1.28-2.16]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars723919-AResearch Support, Non-U.S. Gov'tACDH13
1683342301rs763727GArs763727239672697.15E-05NA1.3[1.30-2.19]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars763727-AResearch Support, Non-U.S. Gov'tGCDH13
1683342301rs763727GArs763727239672697.61E-05NA1.32[1.32-2.32]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars763727-GResearch Support, Non-U.S. Gov'tGCDH13
1683348824rs1035569AGrs1035569239672697.34E-05NA1.3[1.30-2.20]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1035569-AResearch Support, Non-U.S. Gov'tACDH13
1683349398rs7194029TCrs7194029239672696.25E-05NA1.3[1.30-2.21]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7194029-TResearch Support, Non-U.S. Gov'tTCDH13
1683349398rs7194029TCrs7194029239672699.19E-05NA1.31[1.31-2.32]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7194029-TResearch Support, Non-U.S. Gov'tTCDH13
1683358288rs6563897AGrs6563897239672691.10E-04NA1.28[1.28-2.17]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6563897-GResearch Support, Non-U.S. Gov'tA,GCDH13
1683358776rs6563898AGrs6563898239672693.60E-05NA1.35[1.35-2.44]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6563898-GResearch Support, Non-U.S. Gov'tGCDH13
1683358776rs6563898AGrs6563898239672698.00E-06NA1.82[1.39-2.38]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6563898-GResearch Support, Non-U.S. Gov'tGCDH13
1683393302rs1424169GArs1424169239672698.42E-05NA1.65[1.65-4.47]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1424169-AResearch Support, Non-U.S. Gov'tGCDH13
1683457455rs9925521TGrs9925521238296865.75E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTCDH13
1684009402rs2247470TCrs2247470239672696.73E-05NA1.54NA329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2247470-AResearch Support, Non-U.S. Gov'tGNECAB2
1684233536rs7185137CTrs7185137217900087.00E-06Lung function, peak expiratory flowNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
1684262109rs7196274GArs7196274219078641.30E-06NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1684839954rs8057431CArs8057431225615311.20E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
178547rs2396789TCrs2396789237067090.000025NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
1722211rs2294074GArs28702002237067090.0000003NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
17257557rs4130140GArs4130140110220112.30E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars4130140-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
172938533rs9895098TCrs9895098248242163.00E-07(Latino, female)2.31[1.90-2.80] 1,052 European ancestry male cases; 1,019 European ancestry female cases; 709 European ancestry male controls; 826 European ancestry female controls; 675 African ancestry male cases; 837 African ancestry female cases; 577 African ancestry male controls; 926 African ancestry female controls; 926 Latino male cases; 710 Latino female cases; 410 Latino male controls; 382 Latino female controlsAfrican(3015)European(3606)Latino(2428)ALL(9049)HIS(2428)AFR(3015)EUR(3606)ALL(9049)Asthma (sex interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
176431123rs6502960AGrs6502960237067090.0000081NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGPITPNM3
178099183rs9891949GArs9891949218045494.47E-04NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
178099183rs9891949GArs9891949230408850.000000058NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1710362269rs2108606CTrs2108606239672693.37E-05NA1.55[1.55-3.39]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2108606-CResearch Support, Non-U.S. Gov'tCMYH4
1710362269rs2108606CTrs2108606239672696.18E-05NA1.46[1.46-3.02]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2108606-CResearch Support, Non-U.S. Gov'tCMYH4
1710431275rs12952334AGrs12952334239672691.40E-05NA1.61[1.61-3.51]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12952334-AResearch Support, Non-U.S. Gov'tGMYH2
1710431275rs12952334AGrs12952334239672693.29E-05NA1.49[1.49-3.09]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12952334-AResearch Support, Non-U.S. Gov'tGMYH2
1713559080rs10521233AGrs10521233225604793.00E-06NA0.14[NA] unit decrease573 European ancestry childrenEuropean(573)ALL(573)EUR(573)ALL(573)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmars10521233-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1714646168rs7211689ACrs7211689239672691.30E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
1717126041rs2292527GArs2292527238296861.50E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCFLCN
1726092037rs944722CTrs944722243154511.00E-09NA0.07[0.049-0.097] unit decrease5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
1726092037rs944722CTrs944722243154513.00E-07(EA)0.08[0.046-0.104] unit decrease5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars944722-CMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1726093333rs2297515ACrs2297515110220112.13E-06phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2297515-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1726206414rs3751972CArs3751972243154512.00E-10NA0.09[0.059-0.113] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
1726206414rs3751972CArs3751972243154517.00E-09(EA)0.1[0.064-0.126] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3751972-CMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1726247888rs11653617GArs11653617pha0031284.84E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGNANA
1728661392rs3110093AGrs3110093237067090.0000009NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
1731710972rs1021891CTrs1021891239672698.94E-05NA1.36[1.36-2.54]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars1021891-AResearch Support, Non-U.S. Gov'tGASIC2
1737365699rs486512CTrs486512176114961.70E-13NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737610123rs11655550TCrs11655550176114967.59E-04NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1737814080rs1877031GArs1877031208605032.76E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737817482rs2271308TCrs2271308208605034.78E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1737817482rs2271308TCrs2271308219078641.70E-10NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1737821435rs113612868GGTrs931992208605032.73E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737821435rs931992GTrs931992208605032.73E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737824339rs3764351GArs3764351208605031.21E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737828745rs2941503AGrs2941503208605038.52E-09NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1737830900rs2941504AGrs2941504208605038.30E-09NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1737830900rs2941504AGrs2941504221885911.48E-06AsthmaNANA490 Chinese cases; 490 Chinese controlsChinese(980)ALL(980)ASN(980)ALL(980)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, Non-U.S. Gov'tGPGAP3
1737831035rs1565922AGrs1565922208605031.10E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1737834541rs12150298TCrs12150298208605036.57E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737843681rs2517955CTrs2517955218045492.19E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737861718rs2952155TCrs2952155218045493.63E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737866005rs1810132CTrs1810132208605031.16E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1737866005rs1810132CTrs1810132218045492.31E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737868715rs4252627CTrs4252627208605031.01E-05NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737884037rs1058808CGrs1058808218045498.33E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737884037rs1058808CGrs1058808221885917.81E-04AsthmaNANA490 Chinese cases; 490 Chinese controlsChinese(980)ALL(980)ASN(980)ALL(980)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, Non-U.S. Gov'tCERBB2
1737921742rs907091CTrs907091176114965.01E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737922259rs907092GArs907092176114961.20E-09NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1737922259rs907092GArs907092208605038.53E-14NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1737922259rs907092GArs907092218045493.24E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737922259rs907092GArs907092244060735.70E-13NA1.49[1.33-1.49]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1737929816rs2313430TCrs2313430218045491.94E-11NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737938047rs10445308CTrs10445308176114961.10E-04NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1737938047rs10445308CTrs10445308218045498.39E-13NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737970149rs9909593AGrs9909593218045495.23E-13NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737976469rs9303277CTrs9303277176114961.26E-22NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1737976469rs9303277CTrs9303277208605032.52E-15NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1737976469rs9303277CTrs9303277218045491.01E-11NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1737985801rs3816470AGrs3816470218045498.22E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738024626rs11557466CTrs11557466218045496.02E-13NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738025208rs11078925TCrs11078925218045491.86E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738025417rs12150079GArs12150079208605035.02E-09NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738025417rs12150079GArs12150079218045491.98E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738028634rs11557467GTrs11557467176114963.16E-23NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738028634rs11557467GTrs11557467208605034.82E-15NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738029120rs12936231CGrs12936231218045491.95E-10NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738030205rs11870965TArs11870965218045494.04E-10NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738031714rs10852936CTrs10852936176114962.40E-04NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738033277rs1054609ACrs1054609176114963.31E-04NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738033277rs1054609ACrs1054609218045492.23E-10NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738035116rs9907088GArs9907088218045493.16E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738036586rs9904624AGrs9904624218045491.63E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738040119rs12232497TCrs12232497218045491.21E-13NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738040763rs2872507GArs2872507208605035.52E-14NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738040763rs2872507GArs2872507211508785.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738040763rs2872507GArs2872507218045496.84E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738043343rs9901146GArs9901146218045495.57E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738049233rs12950743TCrs12950743218045495.30E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738049589rs7359623CTrs7359623218045494.64E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738051348rs8067378AGrs8067378176114962.00E-23NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738051348rs8067378AGrs8067378208605031.61E-15NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738051348rs8067378AGrs8067378218045496.43E-11NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738053889rs2123685TCrs2123685176114962.14E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738057197rs8069176GArs8069176176114963.80E-10NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738057197rs8069176GArs8069176218045495.66E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738057197rs8069176GArs8069176243154512.00E-08NA0.07[0.042-0.09] unit decrease5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
1738057197rs8069176GArs8069176243154515.00E-06(EA)0.07[0.039-0.093] unit decrease5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars8069176-AMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1738062196rs2305480GArs2305480176114963.00E-09NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738062196rs2305480GArs2305480208605031.00E-07NA1.18[1.11-1.23] 10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2305480-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738062196rs2305480GArs2305480218045491.31E-13NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738062196rs2305480GArs2305480219078649.60E-08NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738062196rs2305480GArs2305480225615319.60E-08NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738062196rs2305480GArs2305480242415376.00E-23NA1.32[1.23-1.39] 1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2305480-GNACGSDMB
1738062217rs2305479CTrs2305479176114968.91E-12NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG,A
1738062217rs2305479CTrs2305479218045491.21E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738062976rs11078926GArs11078926176114964.37E-04NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG,A
1738064405rs11078927CTrs11078927218045492.00E-16NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738064405rs11078927CTrs11078927244060732.40E-10NA1.42[1.27-1.58]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1738066240rs2290400TCrs2290400176114963.98E-23NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738066240rs2290400TCrs2290400208605039.09E-16NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738066240rs2290400TCrs2290400218045493.75E-11NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738066240rs2290400TCrs2290400pha0031279.77E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGGSDMBintron
1738066267rs1008723GTrs1008723176114962.24E-05NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738066267rs1008723GTrs1008723218045497.96E-13NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738066267rs1008723GTrs1008723pha0031279.77E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATGSDMBintron
1738067020rs4795400CTrs4795400176114962.51E-08NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738067020rs4795400CTrs4795400218045491.38E-13NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738068043rs869402TCrs869402218045493.46E-14NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738068043rs869402TCrs869402236662770.000125NANANA745 African American cases; 3238 African American controlsAfrican American(3983)ALL(3983)AFR(3983)ALL(3983)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1738069949rs7216389CTrs7216389176114969.00E-11NA1.45[1.17-1.81]994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7216389-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738069949rs7216389CTrs7216389208605031.29E-15NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738069949rs7216389CTrs7216389218045494.99E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738069949rs7216389CTrs7216389244060739.30E-09NA1.35[1.22-1.50]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1738074031rs9303280TCrs9303280218045494.09E-13NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738074046rs9303281GArs9303281176114961.82E-12NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738074046rs9303281GArs9303281218045493.67E-12NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738074518rs7219923CTrs7219923176114961.66E-12NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738074518rs7219923CTrs7219923218045493.25E-11NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738075426rs7224129GArs7224129218045491.16E-11NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738080865rs4065275AG,Trs4065275176114961.26E-11NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738080912rs8076131GArs8076131176114961.91E-10NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738080912rs8076131GArs8076131218045498.62E-14NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738082807rs12603332TCrs12603332218045494.93E-11NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738084350rs3744246TCrs3744246208605036.00E-04NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738085385rs4795402ACrs4795402176114966.03E-04NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738085722rs4795403TCrs4795403218045495.58E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738088417rs4795405TCrs4795405176114962.51E-15NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738088417rs4795405TCrs4795405208605031.01E-13NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738088417rs4795405TCrs4795405218045491.49E-10NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738089344rs4794820AGrs4794820176114961.35E-09NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738089344rs4794820AGrs4794820218045492.38E-09NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738089344rs4794820AGrs4794820225615311.00E-08NA1.33[1.20-1.45] 933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738091660rs7207600GArs7207600176114964.17E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738092713rs8079416TCrs8079416176114961.26E-11NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738092713rs8079416TCrs8079416208605033.53E-14NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738092713rs8079416TCrs8079416218045492.42E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738092713rs8079416TCrs8079416219078642.40E-22NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738095174rs6503525GCrs6503525176114965.50E-10NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738095174rs6503525GCrs6503525211508785.00E-07NA1.33NA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars6503525-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738095174rs6503525GCrs6503525218045492.88E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738099035rs8065126TCrs8065126176114965.89E-07NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738101932rs4065985GCrs4065985218045493.32E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738103016rs3893044TCrs3893044176114963.39E-08NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738106599rs8071050AGrs8071050219078646.30E-10NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738107627rs4795408GArs4795408176114965.01E-11NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738107627rs4795408GArs4795408218045495.55E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738108708rs7209742AGrs7209742176114964.37E-07NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738111234rs8076474GCrs8076474176114963.72E-07NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738111354rs1007654AGrs1007654176114962.24E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738111354rs1007654AGrs1007654208605033.66E-09NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738111419rs1007655GArs1007655176114961.26E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738111845rs2313640CTrs2313640176114968.13E-07NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738114361rs7218742AGrs7218742176114966.03E-07NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738114469rs7218321CTrs7218321176114962.19E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738114516rs7219080ACrs7219080176114962.51E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738114516rs7219080ACrs7219080208605033.33E-09NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738114598rs6503526CTrs6503526176114961.05E-09NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738114598rs6503526CTrs6503526218045496.63E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738114719rs6503527GArs6503527176114961.78E-06NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738119254rs3902025GTrs3902025176114968.71E-08NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738119254rs3902025GTrs3902025208605039.62E-11NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738121993rs3894194GArs3894194176114961.00E-11NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738121993rs3894194GArs3894194208605035.00E-09NA1.17[1.11-1.23] 10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3894194-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738121993rs3894194GArs3894194218045491.92E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738121993rs3894194GArs3894194219078644.60E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738121993rs3894194GArs3894194225615314.60E-09NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738121993rs3894194GArs3894194242415373.00E-21NA1.59[1.44-1.76] 1,173 European ancestry cases; 2,511 European ancestry controls.European(3684)ALL(3684)EUR(3684)ALL(3684)Asthma (childhood, severe)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3894194-ANACGSDMA
1738121993rs3894194GArs3894194244060734.60E-06NA1.26[1.14-1.39]1,893 Latin American cases; 1,881 Latin American controlsLatin American(3774)ALL(3774)HIS(3774)ALL(3774)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1738122680rs7212938GTrs7212938176114967.76E-04NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738122680rs7212938GTrs7212938218045495.68E-07NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1738128648rs3859192CTrs3859192176114967.10E-13NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738128648rs3859192CTrs3859192208605032.20E-11NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738137623rs8075668CTrs8075668208605034.95E-09NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738153473rs12453334CTrs12453334208605032.63E-07NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738160754rs8070454CTrs8070454208605031.99E-06NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738178149rs2302776AGrs2302776176114966.46E-05NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1738182229rs9916158GTrs9916158208605035.75E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1738197914rs11078936TCrs11078936176114964.17E-05NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738197914rs11078936TCrs11078936208605031.67E-08NANANA10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1738254492rs2071427CTrs2071427pha0031284.60E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANR1D1intron
1738579236rs11650680CTrs11650680176114965.60E-12NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1738892689rs758632CTrs758632pha0031283.92E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANATNANA
1739444101rs12451126CTrs12451126237067090.0000089NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
1739453510rs12449502CTrs12449502237067090.0000089NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
1739456179rs8074471GArs8074471237067090.000008NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
1740514201rs744166AGrs744166211508787.00E-12NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1743008970rs17546822TCrs17546822231817881.13E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1749960309rs967676TCrs967676201592423.18E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1750217537rs11079992GArs11079992201592429.24E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1757832391rs2777899TGrs2777899206989756.10E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1761566031rs4343GArs4343231817884.50E-06NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1763018533rs3972219AGrs3972219199100287.11E-06AsthmaNANA464 African American cases; 471 African American controls; 1028 African Caribbean samples (from families)African American(935)African Caribbean(1028)ALL(1963)AFR(1963)ALL(1963)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., Extramural
1768275532rs723498CArs723498201592423.25E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1768319533rs17716091GArs17716091238296865.00E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGNA
1769196263rs16976458CTrs16976458238296864.59E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1770091433rs9903394AGrs9903394235413248.47E-05ppFEV10.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars9903394-AResearch Support, N.I.H., Extramural
1776881703rs4789939TCrs4789939217328296.00E-07NA1.22[1.11-1.35] 856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseaseNAResearch Support, Non-U.S. Gov'tATIMP2
18849178rs1291183ACrs1291183235413244.00E-06ppFEV10.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1291183-TResearch Support, N.I.H., Extramural
18849178rs1291183ACrs1291183235413245.47E-05ppFVC0.18[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars1291183-TResearch Support, N.I.H., Extramural
182946291rs643507CTrs643507235170428.00E-09adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
184147483rs12607175CTrs12607175238296869.10E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCDLGAP1
186908726rs12454415AGrs12454415225027970.000176NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
187028454rs7227276GArs7227276110220116.48E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7227276-GResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1812779947rs2542151GTrs2542151211508785.00E-17NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1812809340rs1893217AGrs1893217211508783.00E-10NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1813799456rs2155668CTrs2155668238296865.58E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1813828444rs9955902TGrs9955902239672691.00E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
1819696670rs9950004ATrs9950004110220115.29E-06phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars9950004-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1825726723rs11083252GArs11083252227920828.20E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1825760028rs11564299AGrs11564299227920824.80E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1836874502rs7233056AGrs7233056110220115.12E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars7233056-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
1840182606rs17694970AGrs17694970217900081.00E-06Lung function, peak expiratory flowNANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractALOC284260
1840182606rs17694970AGrs17694970217900082.00E-06Lung function, forced expiratory volume in 1 second (FEV1)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractALOC284260
1840182606rs17694970AGrs17694970217900082.00E-06Lung function, forced vital capacity (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractALOC284260
1842824095rs7235815CTrs7235815225027970.000554NANANA529 Hispanic cases; 347 Hispanic controlsHispanic(876)ALL(876)HIS(876)ALL(876)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1845979900rs16949218GArs16949218231817881.20E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1847963964rs2119547CTrs2119547110220113.65E-06phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2119547-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1851804702rs3730729CTrs3730729110220114.40E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3730729-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1853928641rs2538026AGrs2538026110220118.91E-07phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2538026-TResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1853934787rs1229598AGrs1229598110220117.83E-07phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars1229598-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tG
1855472316rs41479544GArs41479544238296861.29E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralGATP8B1
1855909630rs17064520CTrs17064520110220113.22E-07phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars17064520-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
1857662696rs11877823GCrs11877823238296868.42E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCNA
1859240251rs17619983GArs17619983217900088.24E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
1859370004rs1945486TArs1945486231817882.19E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1865360863rs2218416TGrs2218416238296861.38E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralALOC643542
1870546470rs2156107CTrs2156107243154511.00E-06(EA)0.2[0.12-0.29] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2156107-CMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1870546470rs2156107CTrs2156107243154513.00E-06NA0.14[0.083-0.205] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
191119019rs2074920CTrs2074920239672691.20E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCSBNO2
191122147rs2072280GArs2072280239672691.50E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tG,ASBNO2
191199676rs35576999GArs35576999237067090.000068NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGNA
1910071669rs2277968CTrs2277968201592424.27E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1914679428rs11085898AGrs11085898235413244.97E-05ppFVC0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars11085898-AResearch Support, N.I.H., Extramural
1915225348rs13301TCrs13301231802723.82E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
1915226611rs2074261CArs2074261231802722.02E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tCILVBL
1915228178rs1468198TCrs1468198231802727.92E-05NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTILVBL
1915228542rs7507755AGrs7507755231802723.28E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tGILVBL
1915228982rs2240299CTrs2240299231802723.15E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tTILVBL
1918132540rs12984174TCrs12984174235413249.00E-06ppFVC0.26[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars12984174-TResearch Support, N.I.H., Extramural
1918141996rs388159CTrs388159235413242.06E-05ppFVC0.22[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars388159-TResearch Support, N.I.H., Extramural
1918141996rs388159CTrs388159235413243.47E-05ppFEV10.19[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars388159-TResearch Support, N.I.H., Extramural
1918433225rs2241351TCrs2241351225615313.50E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1930373392rs335016CArs335016218045495.78E-05NANANA2,088 European American cases; 1,612 African American and African Caribbean cases; 1,688 Hispanic ancestry casesAfrican American,African Caribbean(1612)Hispanic(1688)European American(2088)ALL(5388)HIS(1688)AFR(1612)EUR(2088)ALL(5388)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1931379109rs7245959TCrs7245959243154513.00E-06NA0.06[0.034-0.084] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
1931379109rs7245959TCrs7245959243154516.00E-06(EA)0.07[0.04-0.098] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars7245959-CMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
1933726375rs11672303TCrs11672303226949300.0000622NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1935556123rs2305744GArs2305744239672694.97E-05NA1.37[1.37-2.47]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2305744-GResearch Support, Non-U.S. Gov'tGHPN
1937693438rs320887TCrs320887pha0031283.07E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAC,TZNF585Bintron
1937737850rs320881AGrs320881pha0031283.20E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAANANA
1940306704rs3810385TCrs3810385239672696.00E-05NA1.89[1.89-9.09]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3810385-AResearch Support, Non-U.S. Gov'tANA
1940309305rs3810384CTrs3810384239672696.86E-05NA1.85[1.85-9.09]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3810384-GResearch Support, Non-U.S. Gov'tGNA
1941856886rs2241715ACrs2241715199100303.30E-05Asthma (childhood asthma)NANA492 Hispanic child cases; 984 Hispanic parentsHispanic(1476)ALL(1476)HIS(1476)ALL(1476)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov't
1951360096rs1061477TCrs1061477230408850.000000023NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
1952532271rs2288884CTrs2288884242801045.00E-08NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2288884-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1952552021rs3752120CTrs3752120242801044.81E-08NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3752120-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1952552999rs3450TCrs3450242801047.56E-09NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars3450-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1952586919rs12460587TGrs12460587242801042.00E-09NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars12460587-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1952601399rs11666341GArs11666341242801041.00E-09NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars11666341-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1952607765rs10411428CTrs10411428242801041.00E-09NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars10411428-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1953682042rs16984547TCrs16984547225615314.00E-06NA1.43[1.23-1.66] 933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1955553019rs1671215CArs1671215231802725.77E-04NANANA117 Korean ancestry cases; 685 Korean ancestry controlsKorean(802)ALL(802)ASN(802)ALL(802)Aspirin exacerbated respiratory disease in asthmaticsHPOID:0012042Aspirin-induced asthmaDOID:2841asthmaD055963Asthma, Aspirin-InducedNANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
1956684824rs10405607TCrs10405607206989753.10E-04AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1957132238rs10404342CArs10404342239672698.00E-06NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCZNF71
1957678194rs11672517GArs11672517217328297.00E-14NA1.34[1.25-1.45]856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseasers11672517-AResearch Support, Non-U.S. Gov'tGDUXA
1957984190rs12977381CArs12977381231817881.36E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
203827309rs4815617CTrs4815617201592428.00E-06NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
204655602rs10485513AGrs10485513199100281.00E-04AsthmaNANA464 African American cases; 471 African American controls; 1028 African Caribbean samples (from families)African American(935)African Caribbean(1028)ALL(1963)AFR(1963)ALL(1963)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., Extramural
204655816rs7270994GArs7270994199100281.00E-04AsthmaNANA464 African American cases; 471 African American controls; 1028 African Caribbean samples (from families)African American(935)African Caribbean(1028)ALL(1963)AFR(1963)ALL(1963)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., Extramural
204657017rs6052761TCrs6052761199100282.27E-06AsthmaNANA464 African American cases; 471 African American controls; 1028 African Caribbean samples (from families)African American(935)African Caribbean(1028)ALL(1963)AFR(1963)ALL(1963)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., Extramural
204751487rs6052862TGrs6052862239672695.91E-05NA1.36[1.36-2.46]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars6052862-GResearch Support, Non-U.S. Gov'tTNA
204785315rs2423011GArs2423011239672697.38E-05NA1.3[1.30-2.22]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars2423011-AResearch Support, Non-U.S. Gov'tARASSF2
205247393rs2326614GArs2326614225615314.53E-05NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
206656028rs765302CGrs765302231817889.87E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
206667135rs2223753ATrs2223753231817881.30E-04NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
206705246rs235763TCrs235763237067090.0000031NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCNA
207385958rs6054973TCrs6054973238296861.00E-07NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
209815528rs221013TCrs221013235413243.09E-05ppFVC0.17[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars221013-TResearch Support, N.I.H., Extramural
2011008382rs4813955ACrs4813955239672694.44E-05NA1.38[1.38-2.50]329 Korean ancestry D.p.-positive cases; 548 Korean ancestry D.p.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.p. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4813955-CResearch Support, Non-U.S. Gov'tANA
2011367780rs996384CArs996384239672691.10E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
2011374805rs4610128AGrs4610128239672691.10E-04NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tANA
2015448563rs2208133TCrs2208133217900088.00E-06Lung function, maximal expiration flow at 50% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractTMACROD2
2016708109rs3787509ATrs3787509110220119.03E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars3787509-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
2030527065rs6061043TCrs6061043227920822.20E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2039028436rs8124695CArs8124695217328298.00E-10NA1.48[1.30-1.68]856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseasers8124695-AResearch Support, Non-U.S. Gov'tANA
2039577519rs2223955GArs2223955217900082.00E-06Lung function, maximal expiration flow at 75% forced vital capactiy (FVC)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
2040509905rs12481621GArs12481621231817882.20E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2040811780rs7262414CArs7262414235413249.97E-05ppFVC0.19[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7262414-AResearch Support, N.I.H., Extramural
2040847486rs8115491TCrs8115491235413247.02E-05ppFVC0.2[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars8115491-TResearch Support, N.I.H., Extramural
2041409901rs13042473TGrs13042473243154512.00E-06(EA)0.09[0.053-0.127] unit increase5,131 European ancestry individualsEuropean(5131)ALL(5131)EUR(5131)ALL(5131)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars13042473-GMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
2041409901rs13042473TGrs13042473243154518.00E-06NA0.07[0.038-0.1] unit increase5,131 European ancestry individuals; 1,155 Hispanic individuals; 2,572 individualsNOPOP(2572)European(5131)Hispanic(1155)ALL(8858)NOPOP(2572)HIS(1155)EUR(5131)ALL(8858)Fractional exhaled nitric oxide (childhood)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthma
2043259306rs244072AGrs244072237067090.000091NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTADA
2043506247rs2425656GArs2425656217900081.99E-07Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractANA
2043507254rs2179069ACrs2179069217900084.23E-06Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractANA
2043741523rs734685CTrs734685230408850.0000069NANANA4867 European ancestry; 4644 Latino; 3447 African AmericanAfrican American(3447)European(4867)Latino(4644)ALL(12958)AFR(3447)HIS(4644)EUR(4867)ALL(12958)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthma
2045739758rs6094594GArs6094594pha0031287.23E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAGEYA2intron
2045888390rs11696358CGrs11696358110220119.43E-06phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars11696358-CResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tC
2046876537rs226839TCrs226839231817886.09E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2050383679rs6096573CTrs6096573235413245.92E-05ppFVC0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars6096573-TResearch Support, N.I.H., Extramural
2055533289rs9974012CTrs9974012235413248.72E-05ppFVC0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars9974012-TResearch Support, N.I.H., Extramural
2059637942rs2093154GTrs2093154213592102.00E-04Pediatric allergic asthmaNANA135 European ancestry children with asthma; 134 European ancestry children with rhinoconjunctivitisEuropean(269)ALL(269)EUR(269)ALL(269)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAMeta-AnalysisResearch Support, Non-U.S. Gov'tG
2116805220rs1736135TCrs1736135211508787.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2116805220rs1736135TCrs1736135219078647.00E-09NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2118452225rs7281703TGrs7281703235413246.98E-05ppFVC0.33[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars7281703-TResearch Support, N.I.H., Extramural
2122810077rs2826840AGrs2826840227920821.00E-04NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2128207390rs229040ACrs229040110220115.15E-05phs000123NANA693 HutteritesHutterite(693)ALL(693)EUR(693)ALL(693)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars229040-AResearch Support, U.S. Gov't, P.H.S.Research Support, Non-U.S. Gov'tA
2129476477rs2037986GTrs2037986176114964.00E-07NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2140400958rs2242930GArs2242930227920825.20E-05NANANA1,644 European ancestry asthmaticsEuropean(1644)ALL(1644)EUR(1644)ALL(1644)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2143080711rs8132754GTrs8132754231817883.61E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2143129442rs4919929CTrs4919929242801042.22E-05NANANA172 European ancestry cases; 409 European ancestry controlsEuropean(581)ALL(581)EUR(581)ALL(581)Bronchodilator response in asthma (inhaled corticosteroid treatment interaction)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars4919929-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2143296188rs13049896GArs13049896226949300.0000867NANANA813 European ancestry cases; 1,011 European ancestry controlsEuropean(1824)ALL(1824)EUR(1824)ALL(1824)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2145615561rs762421GArs762421211508781.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2145647421rs4819388TCrs4819388211508782.00E-09NANANA986 European descent cases; 1,846 European descent controlsEuropean(2832)ALL(2832)EUR(2832)ALL(2832)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2219921137rs9605030CTrs9605030237067090.0000043NANANA199 cases; 502 controlsNOPOP(701)ALL(701)NOPOP(701)ALL(701)Asthma (exacerbation)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCTXNRD2
2225282765rs139719TCrs139719210722011.60E-06Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tCSGSM1
2226766024rs595817TCrs595817235170421.40E-05adultNANA2,418 European ancestry children; 273 children; 3,321 European ancestry adults; 139 adultsNOPOP(412)European(5739)ALL(6151)NOPOP(412)EUR(5739)ALL(6151)Body mass index (asthmatics)HPOID:0002099HPOID:0001507AsthmaGrowth abnormalityDOID:2841asthmaNANAEFOID:0000270asthmaAsthma
2227657544rs518350CTrs518350235082662.70E-04Recessive ModelNANAUp to 403 European ancestry asthmatic children and their parentsEuropean(403)ALL(403)EUR(403)ALL(403)Asthma (bronchodilator response)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaNANAAsthmars518350-TResearch Support, N.I.H., ExtramuralGNA
2231681150rs11704523GArs11704523231817883.10E-05NANANAUp to 1,238 European ancestry cases; up to 2,617 European ancestry controlsEuropean(3855)ALL(3855)EUR(3855)ALL(3855)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2232710985rs5753959AGrs5753959217900088.24E-06Bronchial asthma, age of onset before age 16NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractGNA
2233479580rs2040403AGrs2040403235413241.96E-05ppFEV10.29[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars2040403-AResearch Support, N.I.H., Extramural
2234799261rs5755023AGrs5755023235413241.75E-05ppFEV10.21[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars5755023-AResearch Support, N.I.H., Extramural
2236919343rs8140240AGrs8140240235413249.95E-05ppFVC0.31[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars8140240-AResearch Support, N.I.H., Extramural
2237534034rs2284033GArs2284033208605031.00E-08NA1.12[1.08-1.16] 10,365 cases; 16,110 controlsNOPOP(26475)ALL(26475)NOPOP(26475)ALL(26475)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmars2284033-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2237534034rs2284033GArs2284033219078641.20E-08NANANA12,475 European ancestry cases; 19,967 European ancestry controlsEuropean(32442)ALL(32442)EUR(32442)ALL(32442)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2237534034rs2284033GArs2284033225615311.20E-08NANANA933 European ancestry cases; 3,346 European ancestry controlsEuropean(4279)ALL(4279)EUR(4279)ALL(4279)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2244042348rs16990878CTrs16990878238296865.93E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralCEFCAB6
2244530844rs2267616ACrs2267616pha0031283.03E-05phs000355phs000501NANANAALL(0)ALL(0)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNANAAPARVBintron
2244741589rs8137340TCrs8137340206989752.50E-05AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2245169376rs132470CTrs132470239672691.13E-05NA1.44[1.44-2.61]404 Korean ancestry D.f.-positive cases; 473 Korean ancestry D.f.-negative casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmatics (D.f. specific)HPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmars132470-CResearch Support, Non-U.S. Gov'tTARHGAP8
2245622351rs5766564AGrs5766564239672692.48E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tGKIAA0930
2245634738rs11090735TCrs11090735239672699.64E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tC,TKIAA0930
2245638535rs5766584GTrs5766584239672699.05E-05NANANA877 Korean ancestry casesKorean(877)ALL(877)ASN(877)ALL(877)IgE levels in asthmaticsHPOID:0002099AsthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTNA
2245668012rs58667CTrs58667235413244.00E-07ppFEV10.18[NA] unit increase1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars58667-AResearch Support, N.I.H., Extramural
2245711854rs104664GArs104664235413246.14E-05FEV1/FVC ratio0.22[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars104664-AResearch Support, N.I.H., Extramural
2245736153rs3827393GArs3827393235413247.02E-05FEV1/FVC ratio0.22[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars3827393-AResearch Support, N.I.H., Extramural
2245742760rs6006992AGrs6006992235413247.24E-05FEV1/FVC ratio0.22[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars6006992-AResearch Support, N.I.H., Extramural
2245767369rs470062AGrs470062235413246.21E-05FEV1/FVC ratio0.22[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars470062-AResearch Support, N.I.H., Extramural
2246421842rs6519955GTrs6519955217328293.00E-33NA1.54[1.44-1.65]856 European ancestry cases; 2,836 European ancestry controlsEuropean(3692)ALL(3692)EUR(3692)ALL(3692)Dupuytren's diseaseHPOID:0002099AsthmaDOID:8936plantar fascial fibromatosisD004387Dupuytren ContractureEFOID:0004229dupuytren contractureConnective tissue diseasers6519955-AResearch Support, Non-U.S. Gov'tTNA
2248607014rs5767064GArs5767064235413242.79E-05FEV1/FVC ratio0.16[NA] unit decrease1,544 European ancestry individualsEuropean(1544)ALL(1544)EUR(1544)ALL(1544)Pulmonary function in asthmaticsHPOID:0005952HPOID:0002099Decreased pulmonary functionAsthmaDOID:2841asthmaNANANANAAsthmars5767064-AResearch Support, N.I.H., Extramural
2250101815rs12168899TCrs12168899238296862.60E-06NANANA429 European ancestry affected offspring triosEuropean(429)ALL(429)EUR(429)ALL(429)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralTNA
2250885775rs1053744AGrs1053744210722013.00E-07Aspirin-intolerant asthmaNANA80 Korean cases; 100 Korean controlsKorean(180)ALL(180)ASN(180)ALL(180)Asthma (aspirin-intolerant)HPOID:0012042Aspirin-induced asthmaDOID:2841asthmaNANANANAAsthmaNAResearch Support, Non-U.S. Gov'tTSBF1
X3463531rs2895159GArs2895159217900087.12E-06Allergic diseases (bronchial asthma,allergic rhinitis, atopic dermatitis,food allergy, drug allergy, pollen allergy,urticaria, Quincke?s edema)NANA686 Russian individualsRussian(686)ALL(686)EUR(686)ALL(686)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAEnglish AbstractCNA
X34403462rs5928535TCrs5928535201592429.65E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
X71538575rs646297TCrs646297201592426.98E-05NANANA607 cases; 3,294 white controlsNOPOP(3901)ALL(3901)NOPOP(3901)ALL(3901)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't
X75788843rs2311978TCrs2311978176114962.00E-09NANANA994 cases; 1,243 controlsNOPOP(2237)ALL(2237)NOPOP(2237)ALL(2237)Asthma (childhood onset)HPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0004591childhood onset asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tNA
X95272658rs2761647TGrs2761647206989755.83E-06AsthmaNANA359 European ancestry cases; 846 European ancestry controlsEuropean(1205)ALL(1205)EUR(1205)ALL(1205)AsthmaHPOID:0002099AsthmaDOID:2841asthmaD001249AsthmaEFOID:0000270asthmaAsthmaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:22)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0004096acetaminophenD000082103-90-2asthmaMESH:D001249marker/mechanism15942102
C0004096arsenic trioxideC0066321327-53-3asthmaMESH:D001249therapeutic23210436
C0004096carbimazoleD00223122232-54-8asthmaMESH:D001249therapeutic3968675
C0004096cromolyn sodiumD00420515826-37-6asthmaMESH:D001249therapeutic7437783
C0004096decitabineC0143472353-33-5asthmaMESH:D001249therapeutic23423710
C0004096flunisolideC0077343385/3/3asthmaMESH:D001249therapeutic16696591
C0004096glutathioneD00597870-18-8asthmaMESH:D001249marker/mechanism22867017
C0004096glycopyrrolateD006024596-51-0asthmaMESH:D001249therapeutic3392363
C0004096lansoprazoleD064747-asthmaMESH:D001249therapeutic16778364
C0004096lindaneD00155658-89-9asthmaMESH:D001249marker/mechanism19541724
C0004096loratadineD01733679794-75-5asthmaMESH:D001249therapeutic9196086
C0004096dextromethorphanD003915125-71-3asthmaMESH:D001249marker/mechanism6375709
C0004096methotrexateD0087271959/5/2asthmaMESH:D001249therapeutic1450620
C0004096montelukastC093875158966-92-8asthmaMESH:D001249therapeutic10075616
C0004096nitric oxideD00956910102-43-9asthmaMESH:D001249marker/mechanism16696591
C0004096propranololD011433525-66-6asthmaMESH:D001249therapeutic8687243
C0004096terfenadineD01659350679-08-8asthmaMESH:D001249therapeutic8006312
C0004096theophyllineD01380658-55-9asthmaMESH:D001249therapeutic10596698
C0004096timololD01399926839-75-8asthmaMESH:D001249marker/mechanism7402591
C0004096tretinoinD014212302-79-4asthmaMESH:D001249therapeutic16456186
C0004096vitamin aD01480111103-57-4asthmaMESH:D001249marker/mechanism16732791
C0004096zafirlukastC062735107753-78-6asthmaMESH:D001249therapeutic10027429
FDA approved drug and dosage information(Total Drugs:17)
DiseaseID Drug_name active_ingredients strength Dosage Form/Route Marketing Status TE code RLD RS
MESH:D001249claritinloratadine10MGTABLET;ORALOver-the-counterNoneYesYes
MESH:D001249claritinloratadine1MG/MLSYRUP;ORALOver-the-counterNoneYesYes
MESH:D001249claritinloratadine10MGCAPSULE;ORALOver-the-counterNoneYesYes
MESH:D001249loratadineloratadine10MGTABLET;ORALDiscontinuedNoneNoNo
MESH:D001249loratadineloratadine1MG/MLSUSPENSION;ORALOver-the-counterNoneYesYes
MESH:D001249nasalcromcromolyn sodium5.2MG/SPRAY Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasonsSPRAY, METERED;NASALDiscontinuedNoneYesNo
MESH:D001249prevacidlansoprazole15MGCAPSULE, DELAYED REL PELLETS;ORALPrescriptionABYesNo
MESH:D001249prevacidlansoprazole15MG/PACKETFOR SUSPENSION, DELAYED RELEASE;ORALDiscontinuedNoneNoNo
MESH:D001249prevacidlansoprazole15MGTABLET, DELAYED RELEASE, ORALLY DISINTEGRATING;ORALPrescriptionNoneYesNo
MESH:D001249prevacidlansoprazole15MGCAPSULE, DELAYED REL PELLETS;ORALPrescriptionABYesNo
MESH:D001249prevacidlansoprazole15MG/PACKETFOR SUSPENSION, DELAYED RELEASE;ORALDiscontinuedNoneNoNo
MESH:D001249prevacidlansoprazole15MGTABLET, DELAYED RELEASE, ORALLY DISINTEGRATING;ORALPrescriptionNoneYesNo
MESH:D001249ofirmevacetaminophen1GM/100ML (10MG/ML)SOLUTION;IV (INFUSION)PrescriptionAPYesYes
MESH:D001249ofirmevacetaminophen1GM/100ML (10MG/ML)SOLUTION;IV (INFUSION)PrescriptionAPYesYes
MESH:D001249acetaminophenacetaminophen650MGSUPPOSITORY;RECTALOver-the-counterNoneYesYes
MESH:D001249acetaminophenacetaminophen650MGSUPPOSITORY;RECTALOver-the-counterNoneYesYes
MESH:D001249inomaxnitric oxide100PPM Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasonsGAS;INHALATIONDiscontinuedNoneYesNo
FDA labeling changes(Total Drugs:17)
DiseaseID Pediatric_Labeling_Date Trade_Name Generic_Name_or_Proper_Name Indications Studied Label Changes Summary Product Labeling BPCA(B) PREA(P) BPCA(B) and PREA(P) Pediatric Rule (R) Sponsor Pediatric Exclusivity Granted Date NNPS
MESH:D0012494/12/2000claritinloratadineAllergic rhinitis/UrticariaLabeling for 2 - 5 year olds including information on dose, PK parameters and AE profile PK parameter in 2-5 year olds given a 5mg dose was comparable to the 10mg dose in children 6 years to adolescenceLabelingB---Schering08/14/2000FALSE'
MESH:D0012494/12/2000claritinloratadineAllergic rhinitis/UrticariaLabeling for 2 - 5 year olds including information on dose, PK parameters and AE profile PK parameter in 2-5 year olds given a 5mg dose was comparable to the 10mg dose in children 6 years to adolescenceLabelingB---Schering08/14/2000FALSE'
MESH:D0012494/12/2000claritinloratadineAllergic rhinitis/UrticariaLabeling for 2 - 5 year olds including information on dose, PK parameters and AE profile PK parameter in 2-5 year olds given a 5mg dose was comparable to the 10mg dose in children 6 years to adolescenceLabelingB---Schering08/14/2000FALSE'
MESH:D0012494/12/2000claritinloratadineAllergic rhinitis/UrticariaLabeling for 2 - 5 year olds including information on dose, PK parameters and AE profile PK parameter in 2-5 year olds given a 5mg dose was comparable to the 10mg dose in children 6 years to adolescenceLabelingB---Schering08/14/2000FALSE'
MESH:D0012494/12/2000claritinloratadineAllergic rhinitis/UrticariaLabeling for 2 - 5 year olds including information on dose, PK parameters and AE profile PK parameter in 2-5 year olds given a 5mg dose was comparable to the 10mg dose in children 6 years to adolescenceLabelingB---Schering08/14/2000FALSE'
MESH:D00124903/27/2001nasalcromcromolynPrevention and relief of nasal symptoms of hay fever and other nasal allergiesEstablished proper dose in 2 year - 6 year olds and provided additional safety and compliance data for this age groupLabelingB---Pharmacia & Upjohn2/11/1999FALSE'
MESH:D00124906/17/2004prevacidlansoprazoleShort-term treatment of symptomatic GERD and erosive EsophagitisExpanded age range to include patients 12 -17 years of age; previously labeled only in pediatric patients 1-11 years of age Safety and effectiveness in pediatric patientsLabelingB---Tap07/15/2008FALSE'
MESH:D00124906/17/2004prevacidlansoprazoleShort-term treatment of symptomatic GERD and erosive EsophagitisExpanded age range to include patients 12 -17 years of age; previously labeled only in pediatric patients 1-11 years of age Safety and effectiveness in pediatric patientsLabelingB---Tap07/15/2008FALSE'
MESH:D00124906/17/2004prevacidlansoprazoleShort-term treatment of symptomatic GERD and erosive EsophagitisExpanded age range to include patients 12 -17 years of age; previously labeled only in pediatric patients 1-11 years of age Safety and effectiveness in pediatric patientsLabelingB---Tap07/15/2008FALSE'
MESH:D00124910/28/2008prevacidlansoprazoleSymptomatic GERD in infantsEffectiveness was not established in a 4 week multicenter, double-blind, placebo-controlled study of patients 1 month and < 12 months of age AE profile similar to that observed in adultsInformation on PK parameters in neonates to < 1 year, and clinical studiesLabeling--B, P-Takeda07/15/2008FALSE'
MESH:D00124910/28/2008prevacidlansoprazoleSymptomatic GERD in infantsEffectiveness was not established in a 4 week multicenter, double-blind, placebo-controlled study of patients 1 month and < 12 months of age AE profile similar to that observed in adultsInformation on PK parameters in neonates to < 1 year, and clinical studiesLabeling--B, P-Takeda07/15/2008FALSE'
MESH:D00124910/28/2008prevacidlansoprazoleSymptomatic GERD in infantsEffectiveness was not established in a 4 week multicenter, double-blind, placebo-controlled study of patients 1 month and < 12 months of age AE profile similar to that observed in adultsInformation on PK parameters in neonates to < 1 year, and clinical studiesLabeling--B, P-Takeda07/15/2008FALSE'
MESH:D0012492/11/2010ofirmevacetaminophenManagement of mild-to-moderate pain, for the management of moderate-to-severe pain with adjunctive opioid analgesics, and for the reduction of feverThe safety and effectiveness of Ofirmev for the treatment of acute pain and fever in pediatric patients ages 2 years and older is supported by evidence from adequate and well-controlled studies of Ofirmev in adults. Additional safety and PK data was collected in 355 from premature neonates to adolescents. The effectiveness of Ofirmev for the treatment of acute pain and fever has not been studied in pediatric patients < 2 years of age.The PK exposure of Ofirmev observed in children and adolescents is similar to adults, but higher in neonates and infants. Dosing simulations from PK data in infants and neonates suggest that dose reductions of 33% in infants 1 month to < 2 years of age, and 50% in neonates up to 28 days, with a minimum dosing interval of 6 hours, will produce a PK exposure similar to that observed in children age 2 years and olderMost common adverse reactions in pediatric patients were nausea, vomiting, constipation, pruritus, agitation, and atelectasis.Information on dosing, clinical studies, adverse reactions and PK parametersNew dosage form and route of administrationLabeling-P--Cadence-FALSE'
MESH:D00124901/27/2017ofirmevacetaminophenTreatmeny of pain and fever in pediatric patients birth to 2 yearsTreatment of pain Efficacy was not demonstrated in pediatric patients younger than 2 years in a double-blind, placebo-controlled study of 198 pediatric patients younger than 2 years. Pediatric patients less than 2 years of age, including neonates from 28 to 40 weeks gestational age at birth, were randomized to receive opioid plus acetaminophen or opioid plus placebo. No difference in analgesic effect of intravenous acetaminophen, measured by assessment of reduced need for additional opioid treatment for pain control, was observed. Treatment of fever The safety and effectiveness for the treatment of fever in pediatric patients, including premature neonates born at 32 weeks or greater gestation is supported by adequate and well-controlled studies of Ofirmev in adults, clinical studies in 244 pediatric patients 2 years and older, and safety and pharmacokinetic data from 239 patients younger than 2 years including neonates 32 weeks or greater gestational age. Information on dosing, clinical trials. Postmarketing study.Labeling--B,P-Mallinckrodt11/7/2016FALSE
MESH:D0012492/11/2010ofirmevacetaminophenManagement of mild-to-moderate pain, for the management of moderate-to-severe pain with adjunctive opioid analgesics, and for the reduction of feverThe safety and effectiveness of Ofirmev for the treatment of acute pain and fever in pediatric patients ages 2 years and older is supported by evidence from adequate and well-controlled studies of Ofirmev in adults. Additional safety and PK data was collected in 355 from premature neonates to adolescents. The effectiveness of Ofirmev for the treatment of acute pain and fever has not been studied in pediatric patients < 2 years of age.The PK exposure of Ofirmev observed in children and adolescents is similar to adults, but higher in neonates and infants. Dosing simulations from PK data in infants and neonates suggest that dose reductions of 33% in infants 1 month to < 2 years of age, and 50% in neonates up to 28 days, with a minimum dosing interval of 6 hours, will produce a PK exposure similar to that observed in children age 2 years and olderMost common adverse reactions in pediatric patients were nausea, vomiting, constipation, pruritus, agitation, and atelectasis.Information on dosing, clinical studies, adverse reactions and PK parametersNew dosage form and route of administrationLabeling-P--Cadence-FALSE'
MESH:D00124901/27/2017ofirmevacetaminophenTreatmeny of pain and fever in pediatric patients birth to 2 yearsTreatment of pain Efficacy was not demonstrated in pediatric patients younger than 2 years in a double-blind, placebo-controlled study of 198 pediatric patients younger than 2 years. Pediatric patients less than 2 years of age, including neonates from 28 to 40 weeks gestational age at birth, were randomized to receive opioid plus acetaminophen or opioid plus placebo. No difference in analgesic effect of intravenous acetaminophen, measured by assessment of reduced need for additional opioid treatment for pain control, was observed. Treatment of fever The safety and effectiveness for the treatment of fever in pediatric patients, including premature neonates born at 32 weeks or greater gestation is supported by adequate and well-controlled studies of Ofirmev in adults, clinical studies in 244 pediatric patients 2 years and older, and safety and pharmacokinetic data from 239 patients younger than 2 years including neonates 32 weeks or greater gestational age. Information on dosing, clinical trials. Postmarketing study.Labeling--B,P-Mallinckrodt11/7/2016FALSE
MESH:D00124912/21/2010inomaxnitric oxidePrevention of bronchopulmonary dysplasiaINOmax is not indicated for prevention of BPD in preterm neonates d 34 weeks gestational age.Efficacy for the prevention of BPD in preterm infants was not established in three ldouble-blind, placebo-controlled clinical trials in a total of 2,149 preterm infants Information on clinical trials, adverse reactionLabelingB---INO Therapeutics2/11/2010FALSE'