PedAM

Pediatric Disease Annotations & Medicines


	aspiration pneumonia

Disease ID	1252
Disease	aspiration pneumonia
Definition	A type of lung inflammation resulting from the aspiration of food, liquid, or gastric contents into the upper RESPIRATORY TRACT.
Synonym	aspiration pneumonia (disorder) aspiration pneumonia nos aspiration pneumonia, nos aspiration pneumonias aspiration pneumonitis inhalation pneumonia pneumonia aspiration pneumonia, aspiration pneumonia, aspiration [disease/finding] pneumonia, inhalation pneumonias, aspiration
DOID	DOID:0050152 DOID:3240
UMLS	C0032290
MeSH	D011015
SNOMED-CT	SNOMEDCT_US_2016_09_01:422588002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:42) C1145670 \| respiratory failure \| 8 C0017168 \| esophageal reflux \| 5 C0017168 \| oesophageal reflux \| 4 C0017168 \| gastroesophageal reflux \| 4 C0162429 \| malnutrition \| 3 C0014848 \| achalasia \| 2 C0524851 \| neurodegenerative disease \| 2 C0032285 \| pneumonia \| 2 C0035222 \| acute respiratory distress syndrome \| 2 C0024110 \| lung abscess \| 2 C0030567 \| parkinson disease \| 2 C1704437 \| respiratory distress syndrome \| 2 C1527311 \| brain edema \| 1 C0003125 \| anorexia nervosa \| 1 C0017168 \| gastro-esophageal reflux \| 1 C0017168 \| esophageal reflux disease \| 1 C1258215 \| ileus \| 1 C0021843 \| bowel obstruction \| 1 C0242966 \| sepsis syndrome \| 1 C0524851 \| neurodegenerative diseases \| 1 C0030446 \| paralytic ileus \| 1 C0035078 \| renal failure \| 1 C0042373 \| vascular disease \| 1 C0030442 \| bulbar palsy \| 1 C0017168 \| gastroesophageal reflux disease \| 1 C0019151 \| hepatic encephalopathy \| 1 C0242966 \| systemic inflammatory response syndrome \| 1 C0010674 \| cystic fibrosis \| 1 C0030567 \| parkinson's disease \| 1 C0011991 \| diarrhea \| 1 C0035229 \| respiratory insufficiency \| 1 C0007785 \| cerebral infarct \| 1 C0022661 \| chronic renal failure \| 1 C0007785 \| cerebral infarction \| 1 C0242966 \| systemic inflammatory response syndrome (sirs) \| 1 C0025164 \| megaesophagus \| 1 C0033975 \| psychosis \| 1 C0238301 \| nasopharyngeal carcinoma \| 1 C0014848 \| esophageal achalasia \| 1 C0002395 \| alzheimer disease \| 1 C0010495 \| cutis laxa \| 1 C0022660 \| acute renal failure \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) NOS2 \| 4843 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:144) 2288 \| FKBP4 \| DISEASES 6583 \| SLC22A4 \| DISEASES 3956 \| LGALS1 \| DISEASES 8106 \| PABPN1 \| DISEASES 8106 \| PABPN1 \| DISEASES 479 \| ATP12A \| DISEASES 479 \| ATP12A \| DISEASES 5327 \| PLAT \| DISEASES 6348 \| CCL3 \| DISEASES 1440 \| CSF3 \| DISEASES 7167 \| TPI1 \| DISEASES 9450 \| LY86 \| DISEASES 9450 \| LY86 \| DISEASES 27136 \| MORC1 \| DISEASES 3336 \| HSPE1 \| DISEASES 5624 \| PROC \| DISEASES 6402 \| SELL \| DISEASES 4317 \| MMP8 \| DISEASES 4317 \| MMP8 \| DISEASES 7276 \| TTR \| DISEASES 51119 \| SBDS \| DISEASES 27112 \| FAM155B \| DISEASES 59272 \| ACE2 \| DISEASES 1401 \| CRP \| DISEASES 1401 \| CRP \| DISEASES 2346 \| FOLH1 \| DISEASES 3569 \| IL6 \| DISEASES 114294 \| LACTB \| DISEASES 6521 \| SLC4A1 \| DISEASES 64377 \| CHST8 \| DISEASES 495 \| ATP4A \| DISEASES 495 \| ATP4A \| DISEASES 11043 \| MID2 \| DISEASES 492 \| ATP2B3 \| DISEASES 1991 \| ELANE \| DISEASES 7301 \| TYRO3 \| DISEASES 2743 \| GLRB \| DISEASES 3383 \| ICAM1 \| DISEASES 1161 \| ERCC8 \| DISEASES 54504 \| CPVL \| DISEASES 5286 \| PIK3C2A \| DISEASES 7008 \| TEF \| DISEASES 5373 \| PMM2 \| DISEASES 6567 \| SLC16A2 \| DISEASES 8562 \| DENR \| DISEASES 25836 \| NIPBL \| DISEASES 51422 \| PRKAG2 \| DISEASES 1636 \| ACE \| DISEASES 5739 \| PTGIR \| DISEASES 643 \| CXCR5 \| DISEASES 729230 \| CCR2 \| DISEASES 6006 \| RHCE \| DISEASES 2487 \| FRZB \| DISEASES 5274 \| SERPINI1 \| DISEASES 213 \| ALB \| DISEASES 213 \| ALB \| DISEASES 10999 \| SLC27A4 \| DISEASES 143501 \| C11orf40 \| DISEASES 11141 \| IL1RAPL1 \| DISEASES 2548 \| GAA \| DISEASES 6504 \| SLAMF1 \| DISEASES 114990 \| VASN \| DISEASES 2147 \| F2 \| DISEASES 572 \| BAD \| DISEASES 171389 \| NLRP6 \| DISEASES 57560 \| IFT80 \| DISEASES 3579 \| CXCR2 \| DISEASES 6863 \| TAC1 \| DISEASES 79054 \| TRPM8 \| DISEASES 55748 \| CNDP2 \| DISEASES 3052 \| HCCS \| DISEASES 3052 \| HCCS \| DISEASES 2318 \| FLNC \| DISEASES 4843 \| NOS2 \| DISEASES 9735 \| KNTC1 \| DISEASES 2520 \| GAST \| DISEASES 2520 \| GAST \| DISEASES 8338 \| HIST2H2AC \| DISEASES 5873 \| RAB27A \| DISEASES 6575 \| SLC20A2 \| DISEASES 64087 \| MCCC2 \| DISEASES 3605 \| IL17A \| DISEASES 7316 \| UBC \| DISEASES 55107 \| ANO1 \| DISEASES 135250 \| RAET1E \| DISEASES 5169 \| ENPP3 \| DISEASES 5116 \| PCNT \| DISEASES 79947 \| DHDDS \| DISEASES 773 \| CACNA1A \| DISEASES 4638 \| MYLK \| DISEASES 4512 \| MT-CO1 \| DISEASES 4860 \| PNP \| DISEASES 4508 \| MT-ATP6 \| DISEASES 343035 \| RD3 \| DISEASES 10767 \| HBS1L \| DISEASES 383 \| ARG1 \| DISEASES 10500 \| SEMA6C \| DISEASES 1893 \| ECM1 \| DISEASES 8337 \| HIST2H2AA3 \| DISEASES 8202 \| NCOA3 \| DISEASES 1288 \| COL4A6 \| DISEASES 6441 \| SFTPD \| DISEASES 79717 \| PPCS \| DISEASES 10269 \| ZMPSTE24 \| DISEASES 546 \| ATRX \| DISEASES 2516 \| NR5A1 \| DISEASES 2833 \| CXCR3 \| DISEASES 26190 \| FBXW2 \| DISEASES 54829 \| ASPN \| DISEASES 3055 \| HCK \| DISEASES 81689 \| ISCA1 \| DISEASES 3274 \| HRH2 \| DISEASES 3274 \| HRH2 \| DISEASES 5293 \| PIK3CD \| DISEASES 51109 \| RDH11 \| DISEASES 114899 \| C1QTNF3 \| DISEASES 4287 \| ATXN3 \| DISEASES 196410 \| METTL7B \| DISEASES 6164 \| RPL34 \| DISEASES 3652 \| IPP \| DISEASES 81502 \| HM13 \| DISEASES 6314 \| ATXN7 \| DISEASES 7442 \| TRPV1 \| DISEASES 9612 \| NCOR2 \| DISEASES 3267 \| AGFG1 \| DISEASES 4295 \| MLN \| DISEASES 2741 \| GLRA1 \| DISEASES 285782 \| CAGE1 \| DISEASES 4671 \| NAIP \| DISEASES 2053 \| EPHX2 \| DISEASES 5333 \| PLCD1 \| DISEASES 9152 \| SLC6A5 \| DISEASES 4586 \| MUC5AC \| DISEASES 727897 \| MUC5B \| DISEASES 727897 \| MUC5B \| DISEASES 4850 \| CNOT4 \| DISEASES 10577 \| NPC2 \| DISEASES 4065 \| LY75 \| DISEASES 820 \| CAMP \| DISEASES 11012 \| KLK11 \| DISEASES 102723508 \| KANTR \| DISEASES 378805 \| LINC-PINT \| DISEASES 7955 \| RNF217-AS1 \| DISEASES 100128252 \| ZNF667-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1252
Disease	aspiration pneumonia
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:42) HP:0002015 \| Swallowing difficulty \| 21 HP:0001297 \| Cerebral vascular events \| 9 HP:0002835 \| Aspiration \| 8 HP:0002878 \| Respiratory failure \| 7 HP:0002020 \| Heartburn \| 4 HP:0012735 \| Coughing \| 4 HP:0002098 \| Respiratory distress \| 4 HP:0002013 \| Emesis \| 3 HP:0100806 \| Sepsis \| 3 HP:0004395 \| Malnutrition \| 3 HP:0001944 \| Dehydration \| 2 HP:0002571 \| Achalasia \| 2 HP:0002202 \| Pleural effusion \| 2 HP:0000969 \| Dropsy \| 2 HP:0002090 \| Pneumonia \| 2 HP:0100749 \| Thoracic pain \| 1 HP:0002140 \| Ischemic stroke \| 1 HP:0011469 \| Nasal regurgitation \| 1 HP:0002181 \| Cerebral edema \| 1 HP:0002590 \| Paralytic ileus \| 1 HP:0001945 \| Fever \| 1 HP:0002480 \| Hepatic encephalopathy \| 1 HP:0002511 \| Late-onset form of familial Alzheimer disease \| 1 HP:0001300 \| Parkinsonism \| 1 HP:0030731 \| Carcinoma \| 1 HP:0000973 \| Dermatomegaly \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0006824 \| Cranial nerve palsy \| 1 HP:0005214 \| Bowel obstruction \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0001250 \| Seizures \| 1 HP:0001283 \| Bulbar palsies \| 1 HP:0002093 \| progressive respiratory failure \| 1 HP:0000709 \| Psychosis \| 1 HP:0002014 \| Diarrhea \| 1 HP:0002902 \| Hyponatremia \| 1 HP:0001824 \| Weight loss \| 1 HP:0001649 \| Tachycardia \| 1 HP:0001609 \| Hoarseness \| 1 HP:0002595 \| Gastrointestinal atony \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0012531 \| Pain \| 1

Disease ID	1252
Disease	aspiration pneumonia
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:8) C1145670 \| respiratory failure \| 7 C0476273 \| respiratory distress \| 4 C0036690 \| sepsis \| 3 C0024110 \| lung abscess \| 2 C0035222 \| acute respiratory distress syndrome \| 2 C0014848 \| achalasia \| 1 C0264490 \| acute respiratory failure \| 1 C0004610 \| bacteremia \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:5)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0032290	chlorpromazine	D002746	50-53-3	pneumonia, aspiration	MESH:D011015	marker/mechanism	9921085
C0032290	fluconazole	D015725	86386-73-4	pneumonia, aspiration	MESH:D011015	therapeutic	1561959
C0032290	methadone	D008691	76-99-3	pneumonia, aspiration	MESH:D011015	marker/mechanism	16997682
C0032290	nitric oxide	D009569	10102-43-9	pneumonia, aspiration	MESH:D011015	marker/mechanism	18573544
C0032290	sucralfate	D013392	54182-58-0	pneumonia, aspiration	MESH:D011015	marker/mechanism	18573544

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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