PedAM

Pediatric Disease Annotations & Medicines


	aseptic meningitis

Disease ID	1267
Disease	aseptic meningitis
Definition	A syndrome characterized by headache, neck stiffness, low grade fever, and CSF lymphocytic pleocytosis in the absence of an acute bacterial pathogen. Viral meningitis is the most frequent cause although MYCOPLASMA INFECTIONS; RICKETTSIA INFECTIONS; diagnostic or therapeutic procedures; NEOPLASTIC PROCESSES; septic perimeningeal foci; and other conditions may result in this syndrome. (From Adams et al., Principles of Neurology, 6th ed, p745)
Synonym	aseptic meningitis (disorder) meningitis aseptic meningitis, aseptic meningitis, aseptic [disease/finding]
DOID	DOID:12157
UMLS	C0025290
MeSH	D008582
SNOMED-CT	SNOMEDCT_US_2016_09_01:301770000
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:26) C0025289 \| meningitis \| 2 C0014038 \| encephalitis \| 2 C0085253 \| adult-onset still's disease \| 2 C0042769 \| viral infection \| 2 C0019348 \| herpes simplex \| 2 C1527311 \| brain edema \| 1 C0008049 \| chickenpox \| 1 C0026691 \| kawasaki disease \| 1 C0010346 \| crohn's disease \| 1 C0036472 \| scrub typhus \| 1 C0024205 \| lymphadenitis \| 1 C0039538 \| teratoma \| 1 C0011854 \| type 1 diabetes \| 1 C0042769 \| virus infection \| 1 C0041327 \| pulmonary tb \| 1 C0026780 \| mumps \| 1 C0011847 \| diabetes \| 1 C0035078 \| renal failure \| 1 C0041471 \| typhus \| 1 C0025007 \| measles \| 1 C0271355 \| sixth nerve palsy \| 1 C0917996 \| cerebral aneurysm \| 1 C0042384 \| vasculitis \| 1 C0042384 \| angiitis \| 1 C0152026 \| retinal vasculitis \| 1 C0026975 \| myelitis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) IL6 \| 3569 \| CTD_human ALB \| 213 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:95) 4710 \| NDUFB4 \| DISEASES 1512 \| CTSH \| DISEASES 2137 \| EXTL3 \| DISEASES 973 \| CD79A \| DISEASES 858 \| CAV2 \| DISEASES 6348 \| CCL3 \| DISEASES 1440 \| CSF3 \| DISEASES 5197 \| PF4V1 \| DISEASES 3558 \| IL2 \| DISEASES 51166 \| AADAT \| DISEASES 3458 \| IFNG \| DISEASES 2026 \| ENO2 \| DISEASES 63923 \| TNN \| DISEASES 54210 \| TREM1 \| DISEASES 7533 \| YWHAH \| DISEASES 6351 \| CCL4 \| DISEASES 1401 \| CRP \| DISEASES 1022 \| CDK7 \| DISEASES 269 \| AMHR2 \| DISEASES 3569 \| IL6 \| DISEASES 3557 \| IL1RN \| DISEASES 25833 \| POU2F3 \| DISEASES 4069 \| LYZ \| DISEASES 1800 \| DPEP1 \| DISEASES 671 \| BPI \| DISEASES 3553 \| IL1B \| DISEASES 3574 \| IL7 \| DISEASES 7531 \| YWHAE \| DISEASES 950 \| SCARB2 \| DISEASES 7879 \| RAB7A \| DISEASES 2028 \| ENPEP \| DISEASES 60314 \| C12orf10 \| DISEASES 5868 \| RAB5A \| DISEASES 3439 \| IFNA1 \| DISEASES 3948 \| LDHC \| DISEASES 54842 \| MFSD6 \| DISEASES 4900 \| NRGN \| DISEASES 1525 \| CXADR \| DISEASES 56934 \| CA10 \| DISEASES 7079 \| TIMP4 \| DISEASES 56896 \| DPYSL5 \| DISEASES 715 \| C1R \| DISEASES 6285 \| S100B \| DISEASES 6352 \| CCL5 \| DISEASES 213 \| ALB \| DISEASES 2923 \| PDIA3 \| DISEASES 762 \| CA4 \| DISEASES 3688 \| ITGB1 \| DISEASES 171558 \| PTCRA \| DISEASES 7532 \| YWHAG \| DISEASES 4968 \| OGG1 \| DISEASES 1473 \| CST5 \| DISEASES 1776 \| DNASE1L3 \| DISEASES 79966 \| SCD5 \| DISEASES 3291 \| HSD11B2 \| DISEASES 201475 \| RAB12 \| DISEASES 114548 \| NLRP3 \| DISEASES 7204 \| TRIO \| DISEASES 22978 \| NT5C2 \| DISEASES 27159 \| CHIA \| DISEASES 3146 \| HMGB1 \| DISEASES 128859 \| BPIFB6 \| DISEASES 58473 \| PLEKHB1 \| DISEASES 79971 \| WLS \| DISEASES 2551 \| GABPA \| DISEASES 163882 \| CNST \| DISEASES 3664 \| IRF6 \| DISEASES 1805 \| DPT \| DISEASES 1268 \| CNR1 \| DISEASES 959 \| CD40LG \| DISEASES 3339 \| HSPG2 \| DISEASES 359710 \| BPIFB3 \| DISEASES 25805 \| BAMBI \| DISEASES 7133 \| TNFRSF1B \| DISEASES 765 \| CA6 \| DISEASES 51567 \| TDP2 \| DISEASES 768 \| CA9 \| DISEASES 3456 \| IFNB1 \| DISEASES 4155 \| MBP \| DISEASES 10675 \| CSPG5 \| DISEASES 55576 \| STAB2 \| DISEASES 4099 \| MAG \| DISEASES 9560 \| CCL4L2 \| DISEASES 7124 \| TNF \| DISEASES 5817 \| PVR \| DISEASES 4049 \| LTA \| DISEASES 388372 \| CCL4L1 \| DISEASES 84148 \| KAT8 \| DISEASES 3586 \| IL10 \| DISEASES 56342 \| PPAN \| DISEASES 246734 \| NPCDR1 \| DISEASES 6625 \| SNRNP70 \| DISEASES 100885779 \| LINC-ROR \| DISEASES 103164619 \| PCAT2 \| DISEASES 654321 \| SNORA75 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1267
Disease	aseptic meningitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:25) HP:0001945 \| Fever \| 3 HP:0000016 \| Urinary retention \| 3 HP:0002315 \| Headaches \| 3 HP:0000969 \| Dropsy \| 2 HP:0002633 \| Vasculitis \| 2 HP:0002383 \| Encephalitis \| 2 HP:0001287 \| Meningitis \| 2 HP:0200119 \| Acute liver inflammation \| 1 HP:0001289 \| Confusion \| 1 HP:0009792 \| Teratoma \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0012531 \| Pain \| 1 HP:0000010 \| Frequent urinary tract infections \| 1 HP:0002018 \| Nausea \| 1 HP:0004944 \| Cerebral artery aneurysm \| 1 HP:0100280 \| Morbus Crohn \| 1 HP:0012486 \| Inflammation of spinal cord \| 1 HP:0001548 \| Overgrowth \| 1 HP:0002840 \| Lymphadenitis \| 1 HP:0002027 \| Abdominal pain \| 1 HP:0002617 \| Aneurysmal dilatation \| 1 HP:0011349 \| Sixth nerve palsy \| 1 HP:0002013 \| Emesis \| 1 HP:0002181 \| Cerebral edema \| 1 HP:0100774 \| Hyperostosis \| 1

Disease ID	1267
Disease	aseptic meningitis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:5) C0009450 \| infection \| 6 C0021311 \| infections \| 4 C0341742 \| acute urinary retention \| 3 C0024205 \| lymphadenitis \| 1 C0398367 \| subacute necrotizing lymphadenitis \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:17)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0025290	baclofen	D001418	1134-47-0	meningitis, aseptic	MESH:D008582	marker/mechanism	16172626
C0025290	bupivacaine	D002045	2180-92-9	meningitis, aseptic	MESH:D008582	marker/mechanism	17641986
C0025290	carbamazepine	D002220	298-46-4	meningitis, aseptic	MESH:D008582	marker/mechanism	2327680
C0025290	carbamazepine	D002220	298-46-4	meningitis, aseptic	MESH:D008582	therapeutic	8067500
C0025290	ciprofloxacin	D002939	85721-33-1	meningitis, aseptic	MESH:D008582	marker/mechanism	18205541
C0025290	diclofenac	D004008	15307-86-5	meningitis, aseptic	MESH:D008582	marker/mechanism	10567617
C0025290	erythromycin	D004917	114-07-8	meningitis, aseptic	MESH:D008582	marker/mechanism	8614533
C0025290	foscarnet	D017245	4428-95-9	meningitis, aseptic	MESH:D008582	therapeutic	11197578
C0025290	ketorolac	D020910	66635-83-4	meningitis, aseptic	MESH:D008582	marker/mechanism	16521060
C0025290	lamotrigine	C047781	84057-84-1	meningitis, aseptic	MESH:D008582	marker/mechanism	15679516
C0025290	methotrexate	D008727	1959/5/2	meningitis, aseptic	MESH:D008582	marker/mechanism	17878395
C0025290	piroxicam	D010894	36322-90-4	meningitis, aseptic	MESH:D008582	marker/mechanism	10567617
C0025290	rifampin	D012293	13292-46-1	meningitis, aseptic	MESH:D008582	marker/mechanism	20674104
C0025290	sulfisoxazole	D013444	127-69-5	meningitis, aseptic	MESH:D008582	marker/mechanism	8614533
C0025290	sulindac	D013467	38194-50-2	meningitis, aseptic	MESH:D008582	marker/mechanism	1763533
C0025290	tolmetin	D014046	26171-23-3	meningitis, aseptic	MESH:D008582	marker/mechanism	1763533
C0025290	trimethoprim	D014295	738-70-5	meningitis, aseptic	MESH:D008582	marker/mechanism	10888991

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

Web
Analytics