PedAM

Pediatric Disease Annotations & Medicines


	anterior uveitis

Disease ID	469
Disease	anterior uveitis
Definition	Inflammation of the anterior uvea comprising the iris, angle structures, and the ciliary body. Manifestations of this disorder include ciliary injection, exudation into the anterior chamber, iris changes, and adhesions between the iris and lens (posterior synechiae). Intraocular pressure may be increased or reduced.
Synonym	anterior uveitides anterior uveitis (disorder) anterior uveitis [ambiguous] anterior uveitis, nos uveitides, anterior uveitis, anterior uveitis, anterior [disease/finding]
Orphanet	ORPHANET:280886
DOID	DOID:1407
UMLS	C0042165
MeSH	D014606
SNOMED-CT	SNOMEDCT_US_2016_09_01:410692006
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:63) C0038013 \| ankylosing spondylitis \| 12 C0553662 \| juvenile idiopathic arthritis \| 8 C0086543 \| cataract \| 7 C0038012 \| spondylitis \| 7 C0003864 \| arthritis \| 7 C0042164 \| uveitis \| 5 C0022568 \| keratitis \| 5 C0017601 \| glaucoma \| 4 C0152253 \| posterior synechiae \| 3 C0271051 \| macular edema \| 3 C0036202 \| sarcoidosis \| 3 C0042769 \| virus infection \| 2 C0020538 \| hypertension \| 2 C0011570 \| depression \| 2 C0028840 \| ocular hypertension \| 2 C0030343 \| panuveitis \| 2 C0042167 \| posterior uveitis \| 1 C0027813 \| neuritis \| 1 C0730306 \| ocular lymphoma \| 1 C0019348 \| herpes simplex \| 1 C0027707 \| interstitial nephritis \| 1 C0152258 \| hypermature cataract \| 1 C0155088 \| interstitial keratitis \| 1 C0022573 \| keratoconjunctivitis \| 1 C0007939 \| chancre \| 1 C0041322 \| ocular tuberculosis \| 1 C0015458 \| parry-romberg syndrome \| 1 C0024299 \| lymphomas \| 1 C0020581 \| hyphema \| 1 C0009324 \| ulcerative colitis \| 1 C0029134 \| optic neuritis \| 1 C0017658 \| glomerulonephritis \| 1 C0281658 \| intraocular lymphoma \| 1 C0010403 \| cryoglobulinemia \| 1 C0544008 \| chandler's syndrome \| 1 C0010037 \| corneal edema \| 1 C0152257 \| mature cataract \| 1 C0009763 \| conjunctivitis \| 1 C0162293 \| papillitis \| 1 C0009447 \| common variable immunodeficiency \| 1 C0004114 \| astrocytoma \| 1 C0152026 \| retinal vasculitis \| 1 C0028817 \| ochronosis \| 1 C0041296 \| tuberculosis \| 1 C0011603 \| dermatitis \| 1 C0085437 \| bacterial meningitis \| 1 C0949691 \| spondyloarthropathy \| 1 C0010678 \| cysticercosis \| 1 C0155223 \| dacryoadenitis \| 1 C0032453 \| relapsing polychondritis \| 1 C0271097 \| usher syndrome \| 1 C0042384 \| vasculitis \| 1 C0949690 \| spondyloarthritis \| 1 C0025290 \| aseptic meningitis \| 1 C0024440 \| cystoid macular edema \| 1 C0036416 \| scleritis \| 1 C0027697 \| nephritis \| 1 C0022081 \| iritis \| 1 C0030353 \| papilloedema \| 1 C0026896 \| myasthenia gravis \| 1 C0007939 \| syphilitic chancre \| 1 C0014236 \| endophthalmitis \| 1 C0042164 \| intraocular inflammation \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:10) 6347 \| CCL2 \| infer 6352 \| CCL5 \| infer 1493 \| CTLA4 \| infer 3383 \| ICAM1 \| infer 3586 \| IL10 \| infer 3557 \| IL1RN \| infer 3569 \| IL6 \| infer 26191 \| PTPN22 \| infer 6648 \| SOD2 \| infer 7124 \| TNF \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:137) 5442 \| POLRMT \| DISEASES 4282 \| MIF \| DISEASES 1414 \| CRYBB1 \| DISEASES 3560 \| IL2RB \| DISEASES 2137 \| EXTL3 \| DISEASES 8797 \| TNFRSF10A \| DISEASES 7991 \| TUSC3 \| DISEASES 973 \| CD79A \| DISEASES 5949 \| RBP3 \| DISEASES 6347 \| CCL2 \| DISEASES 3558 \| IL2 \| DISEASES 3458 \| IFNG \| DISEASES 55856 \| ACOT13 \| DISEASES 3565 \| IL4 \| DISEASES 3554 \| IL1R1 \| DISEASES 8809 \| IL18R1 \| DISEASES 6402 \| SELL \| DISEASES 7128 \| TNFAIP3 \| DISEASES 10804 \| GJB6 \| DISEASES 84329 \| HVCN1 \| DISEASES 6351 \| CCL4 \| DISEASES 1401 \| CRP \| DISEASES 1823 \| DSC1 \| DISEASES 3569 \| IL6 \| DISEASES 3557 \| IL1RN \| DISEASES 7097 \| TLR2 \| DISEASES 4069 \| LYZ \| DISEASES 7188 \| TRAF5 \| DISEASES 384 \| ARG2 \| DISEASES 10133 \| OPTN \| DISEASES 443 \| ASPA \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 10994 \| ILVBL \| DISEASES 55717 \| WDR11 \| DISEASES 941 \| CD80 \| DISEASES 8808 \| IL1RL2 \| DISEASES 3383 \| ICAM1 \| DISEASES 3189 \| HNRNPH3 \| DISEASES 6017 \| RLBP1 \| DISEASES 6687 \| SPG7 \| DISEASES 57410 \| SCYL1 \| DISEASES 8795 \| TNFRSF10B \| DISEASES 4715 \| NDUFB9 \| DISEASES 23643 \| LY96 \| DISEASES 54069 \| MIS18A \| DISEASES 1636 \| ACE \| DISEASES 1409 \| CRYAA \| DISEASES 729230 \| CCR2 \| DISEASES 1234 \| CCR5 \| DISEASES 1584 \| CYP11B1 \| DISEASES 85451 \| UNK \| DISEASES 6352 \| CCL5 \| DISEASES 3577 \| CXCR1 \| DISEASES 213 \| ALB \| DISEASES 1230 \| CCR1 \| DISEASES 51752 \| ERAP1 \| DISEASES 4714 \| NDUFB8 \| DISEASES 64127 \| NOD2 \| DISEASES 56947 \| MFF \| DISEASES 1493 \| CTLA4 \| DISEASES 9655 \| SOCS5 \| DISEASES 3627 \| CXCL10 \| DISEASES 56246 \| MRAP \| DISEASES 81793 \| TLR10 \| DISEASES 5340 \| PLG \| DISEASES 5553 \| PRG2 \| DISEASES 4179 \| CD46 \| DISEASES 767 \| CA8 \| DISEASES 4684 \| NCAM1 \| DISEASES 149233 \| IL23R \| DISEASES 23046 \| KIF21B \| DISEASES 125061 \| AFMID \| DISEASES 81565 \| NDEL1 \| DISEASES 120227 \| CYP2R1 \| DISEASES 114548 \| NLRP3 \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 7100 \| TLR5 \| DISEASES 966 \| CD59 \| DISEASES 84639 \| IL1F10 \| DISEASES 6731 \| SRP72 \| DISEASES 3605 \| IL17A \| DISEASES 766 \| CA7 \| DISEASES 23111 \| SPG20 \| DISEASES 100506658 \| OCLN \| DISEASES 50488 \| MINK1 \| DISEASES 5265 \| SERPINA1 \| DISEASES 9600 \| PITPNM1 \| DISEASES 6775 \| STAT4 \| DISEASES 9652 \| TTC37 \| DISEASES 26191 \| PTPN22 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 54106 \| TLR9 \| DISEASES 676 \| BRDT \| DISEASES 7096 \| TLR1 \| DISEASES 6993 \| DYNLT1 \| DISEASES 3080 \| CFHR2 \| DISEASES 3075 \| CFH \| DISEASES 4942 \| OAT \| DISEASES 8804 \| CREG1 \| DISEASES 959 \| CD40LG \| DISEASES 5737 \| PTGFR \| DISEASES 7422 \| VEGFA \| DISEASES 55315 \| SLC29A3 \| DISEASES 2833 \| CXCR3 \| DISEASES 7099 \| TLR4 \| DISEASES 1896 \| EDA \| DISEASES 5698 \| PSMB9 \| DISEASES 100507436 \| MICA \| DISEASES 3107 \| HLA-C \| DISEASES 7133 \| TNFRSF1B \| DISEASES 3105 \| HLA-A \| DISEASES 8718 \| TNFRSF25 \| DISEASES 7293 \| TNFRSF4 \| DISEASES 3559 \| IL2RA \| DISEASES 4155 \| MBP \| DISEASES 3426 \| CFI \| DISEASES 7913 \| DEK \| DISEASES 337867 \| UBAC2 \| DISEASES 6295 \| SAG \| DISEASES 720 \| C4A \| DISEASES 55683 \| KANSL3 \| DISEASES 653509 \| SFTPA1 \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 4615 \| MYD88 \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 3586 \| IL10 \| DISEASES 721 \| C4B \| DISEASES 7710 \| ZNF154 \| DISEASES 346007 \| EYS \| DISEASES 930 \| CD19 \| DISEASES 1232 \| CCR3 \| DISEASES 11331 \| PHB2 \| DISEASES 567 \| B2M \| DISEASES 79104 \| MEG8 \| DISEASES 100130889 \| PSORS1C3 \| DISEASES
Locus	(Waiting for update.)

Disease ID	469
Disease	anterior uveitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:43) HP:0005681 \| Juvenile idiopathic arthritis \| 8 HP:0000518 \| Cataract \| 7 HP:0001369 \| Arthritis \| 7 HP:0000491 \| Corneal inflammation \| 5 HP:0000554 \| Uveitis \| 5 HP:0000501 \| Glaucoma \| 4 HP:0012531 \| Pain \| 4 HP:0011531 \| Hyalitis \| 3 HP:0011484 \| Posterior synechiae \| 3 HP:0000969 \| Dropsy \| 3 HP:0000613 \| Extreme light sensitivity \| 2 HP:0040049 \| Macular edema \| 2 HP:0000822 \| Hypertension \| 2 HP:0100533 \| Ocular inflammation \| 2 HP:0002829 \| Arthralgias \| 2 HP:0012121 \| Panuveitis \| 2 HP:0000716 \| Depression \| 2 HP:0001096 \| Keratoconjunctivitis \| 1 HP:0009592 \| Astrocytoma \| 1 HP:0012231 \| Exudative retinal detachment \| 1 HP:0001101 \| Iritis \| 1 HP:0010696 \| Polar cataract \| 1 HP:0001134 \| Anterior polar cataract \| 1 HP:0001970 \| Interstitial nephritis \| 1 HP:0100778 \| Cryoglobulinemia \| 1 HP:0000509 \| Conjunctivitis \| 1 HP:0011505 \| Cystoid macular edema \| 1 HP:0000573 \| Retinal hemorrhage \| 1 HP:0100686 \| Enthesitis \| 1 HP:0009916 \| Asymmetric pupil sizes \| 1 HP:0100532 \| Scleritis \| 1 HP:0000123 \| Nephritis \| 1 HP:0030764 \| Ochronosis \| 1 HP:0200026 \| Ocular pain \| 1 HP:0012155 \| Reduced corneal sensation \| 1 HP:0011886 \| Hyphema \| 1 HP:0100279 \| Ulcerative colitis \| 1 HP:0000099 \| Glomerular nephritis \| 1 HP:0003473 \| Fatigable weakness \| 1 HP:0001945 \| Fever \| 1 HP:0012123 \| Posterior uveitis \| 1 HP:0000572 \| Visual loss \| 1 HP:0100653 \| Optic neuritis \| 1

Disease ID	469
Disease	anterior uveitis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:18) C1962983 \| cataract C1306068 \| secondary cataract C0949691 \| spondyloarthropathies C0850666 \| helicobacter pylori infection C0521706 \| unilateral cataract C0456909 \| blindness C0442893 \| systemic disease C0339383 \| chorioretinopathy C0339324 \| spontaneous hyphema C0268780 \| idiopathic acute interstitial nephritis C0152026 \| retinal vasculitis C0149893 \| secondary glaucoma C0043407 \| yersinia infection C0036454 \| scotoma C0033860 \| psoriasis C0011860 \| niddm C0008513 \| retinochoroiditis C0008149 \| chlamydia
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:3) C0086543 \| cataract \| 7 C0442893 \| systemic disease \| 3 C0149893 \| secondary glaucoma \| 2

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0042165	piroxicam	D010894	36322-90-4	uveitis, anterior	MESH:D014606	therapeutic	1987876

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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