PedAM

Pediatric Disease Annotations & Medicines


	angiofollicular lymphoid hyperplasia

Disease ID	1524
Disease	angiofollicular lymphoid hyperplasia
Definition	Large benign, hyperplastic lymph nodes. The more common hyaline vascular subtype is characterized by small hyaline vascular follicles and interfollicular capillary proliferations. Plasma cells are often present and represent another subtype with the plasma cells containing IgM and IMMUNOGLOBULIN A.
Synonym	[d] castleman's disease [d] castleman's disease (disorder) aflh angiofollicular lymph hyperplasia angiofollicular lymph hyperplasias angiofollicular lymph node hyperplasia angiofollicular lymph node hyperplasia (disorder) angiofollicular lymph node hyperplasia (disorder) [ambiguous] angiofollicular lymphoid hyperplasias angiomatous lymphoid hamartoma benign angiofollicular hyperplasia castleman dis castleman disease castleman tumor castleman's disease castleman's disease (disorder) castleman's disease, unicentric castleman's tumor castlemans dis castlemans disease castlemans tumor giant lymph node hyperplasia giant lymph node hyperplasia (disorder) giant lymph node hyperplasia [disease/finding] glnh hyperplasia, angiofollicular lymph hyperplasia, angiofollicular lymphoid hyperplasia, giant lymph node hyperplasias, angiofollicular lymph hyperplasias, angiofollicular lymphoid lymph node hyperplasia, giant lymphoid hyperplasia, angiofollicular lymphoid hyperplasias, angiofollicular tumor, castleman's unicentric castleman's disease
Orphanet	ORPHANET:160
UMLS	C0017531
MeSH	D005871
SNOMED-CT	SNOMEDCT_US_2016_09_01:207036003;SNOMEDCT_US_2016_09_01:238809002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:77) C0024299 \| lymphoma \| 9 C1261473 \| sarcoma \| 6 C1260325 \| follicular dendritic cell sarcoma \| 5 C0002726 \| amyloidosis \| 5 C0026896 \| myasthenia gravis \| 5 C0017658 \| glomerulonephritis \| 4 C0030807 \| pemphigus \| 4 C0235618 \| proliferative glomerulonephritis \| 4 C0079731 \| b-cell lymphoma \| 3 C0002871 \| anemia \| 3 C0017662 \| membranoproliferative glomerulonephritis \| 3 C0040034 \| thrombocytopenia \| 3 C0024141 \| systemic lupus erythematosus \| 2 C0677607 \| hashimoto disease \| 2 C0409974 \| lupus erythematosus \| 2 C0085404 \| poems syndrome \| 2 C0011649 \| dermoid cyst \| 2 C0442874 \| neuropathy \| 2 C0042384 \| vasculitis \| 2 C0029132 \| optic neuropathy \| 2 C0026272 \| mixed connective tissue disease \| 1 C0019069 \| haemophilia \| 1 C1619734 \| pulmonary arterial hypertension \| 1 C0041408 \| turner syndrome \| 1 C0032285 \| pneumonia \| 1 C0079731 \| b cell lymphoma \| 1 C0002880 \| autoimmune hemolytic anemia \| 1 C0043117 \| idiopathic thrombocytopenic purpura \| 1 C0856761 \| budd-chiari syndrome \| 1 C0017661 \| iga nephropathy \| 1 C0019829 \| hodgkin's lymphoma \| 1 C0009447 \| common variable immunodeficiency \| 1 C0015230 \| rash \| 1 C0006271 \| bronchiolitis \| 1 C0035328 \| retinal vein occlusion \| 1 C0006272 \| bronchiolitis obliterans \| 1 C0027726 \| nephrotic syndrome \| 1 C0221238 \| mesangial proliferative glomerulonephritis \| 1 C0024314 \| lymphoproliferative disorder \| 1 C0039520 \| tenosynovitis \| 1 C0878544 \| cardiomyopathy \| 1 C1565489 \| renal insufficiency \| 1 C0036421 \| systemic sclerosis \| 1 C0024115 \| lung disease \| 1 C0018916 \| angioma \| 1 C0021400 \| influenza \| 1 C0021053 \| immune disease \| 1 C0155765 \| microangiopathy \| 1 C0024221 \| lymphangioma \| 1 C0022658 \| kidney disease \| 1 C0155223 \| dacryoadenitis \| 1 C0272286 \| immune thrombocytopenia \| 1 C0001175 \| acquired immune deficiency syndrome \| 1 C0021141 \| syndrome of inappropriate antidiuretic hormone secretion \| 1 C0002880 \| autoimmune haemolytic anaemia \| 1 C0002989 \| angiolymphoid hyperplasia with eosinophilia \| 1 C0002878 \| hemolytic anemia \| 1 C0030305 \| pancreatitis \| 1 C0022658 \| nephropathy \| 1 C0019829 \| hodgkin's disease \| 1 C0020437 \| hypercalcemia \| 1 C0272126 \| evan's syndrome \| 1 C0002989 \| angiolymphoid hyperplasia \| 1 C0011649 \| dermoid \| 1 C0042769 \| virus infection \| 1 C0042164 \| uveitis \| 1 C0001175 \| acquired immune deficiency \| 1 C0027707 \| interstitial nephritis \| 1 C0009782 \| connective tissue disorder \| 1 C0009782 \| connective tissue disease \| 1 C0027059 \| myocarditis \| 1 C0242584 \| autoimmune thrombocytopenia \| 1 C0020538 \| hypertension \| 1 C0162316 \| iron-deficiency anemia \| 1 C0002878 \| haemolytic anaemia \| 1 C0020295 \| hydronephrosis \| 1 C0334634 \| mantle cell lymphoma \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) IL6 \| 3569 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	(Waiting for update.)
Locus	(Waiting for update.)

Disease ID	1524
Disease	angiofollicular lymphoid hyperplasia
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:53) HP:0002665 \| Lymphoma \| 9 HP:0100242 \| Sarcoma \| 6 HP:0003473 \| Fatigable weakness \| 5 HP:0002721 \| Immunodeficiency \| 4 HP:0012191 \| B-cell lymphoma \| 4 HP:0011034 \| Amyloid disease \| 4 HP:0000099 \| Glomerular nephritis \| 4 HP:0001903 \| Anemia \| 3 HP:0000793 \| Membranoproliferative glomerulonephritis \| 3 HP:0001873 \| Low platelet count \| 3 HP:0002716 \| Lymph node hyperplasia \| 3 HP:0001890 \| Autoimmune hemolytic anemia \| 2 HP:0001138 \| Damaged optic nerve \| 2 HP:0001878 \| Haemolytic anaemia \| 2 HP:0001945 \| Fever \| 2 HP:0002633 \| Vasculitis \| 2 HP:0002664 \| Neoplasia \| 1 HP:0001891 \| Iron-deficiency anemia \| 1 HP:0000100 \| Nephrosis \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0012189 \| Hodgkin disease \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0003072 \| Hypercalcemia \| 1 HP:0011946 \| Constrictive bronchiolitis \| 1 HP:0030150 \| Plasmacytosis \| 1 HP:0002719 \| infections, recurrent \| 1 HP:0045073 \| Serositis \| 1 HP:0001917 \| Renal amyloidosis \| 1 HP:0004947 \| Arteriovenous fistula \| 1 HP:0001973 \| Autoimmune thrombocytopenia \| 1 HP:0000112 \| Nephropathy \| 1 HP:0001510 \| Growth deficiency \| 1 HP:0000126 \| Hydronephrosis \| 1 HP:0001733 \| Pancreatic inflammation \| 1 HP:0002090 \| Pneumonia \| 1 HP:0100764 \| Lymphangioma \| 1 HP:0005523 \| Lymphoproliferative disorder \| 1 HP:0007461 \| Hemangiomatosis \| 1 HP:0001638 \| Cardiomyopathy \| 1 HP:0012636 \| Retinal vein occlusion \| 1 HP:0001970 \| Interstitial nephritis \| 1 HP:0200029 \| Cutaneous vasculitis \| 1 HP:0012819 \| Myocarditis \| 1 HP:0030731 \| Carcinoma \| 1 HP:0100570 \| Carcinoid tumor \| 1 HP:0005945 \| Laryngeal obstruction \| 1 HP:0000554 \| Uveitis \| 1 HP:0002639 \| Budd-Chiari syndrome \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0000822 \| Hypertension \| 1 HP:0011950 \| Bronchiolitis \| 1 HP:0008940 \| Generalized lymphadenopathy \| 1 HP:0012050 \| Anasarca \| 1

Disease ID	1524
Disease	angiofollicular lymphoid hyperplasia
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:11) C1112570 \| paraneoplastic pemphigus \| 5 C1261473 \| sarcoma \| 5 C0017658 \| glomerulonephritis \| 3 C0024299 \| lymphoma \| 3 C0002726 \| amyloidosis \| 3 C0221014 \| secondary amyloidosis \| 2 C0442874 \| neuropathy \| 2 C0019829 \| hodgkin's disease \| 1 C2039684 \| systemic symptoms \| 1 C0017661 \| iga nephropathy \| 1 C0020437 \| hypercalcemia \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0017531	thalidomide	D013792	50-35-1	giant lymph node hyperplasia	MESH:D005871	therapeutic	12701121

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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