PedAM

Pediatric Disease Annotations & Medicines


	anaplastic ependymoma

Disease ID	1715
Disease	anaplastic ependymoma
Definition	A WHO grade III malignant glioma of ependymal origin with accelerated growth and an unfavorable clinical outcome, particularly in children. It is characterized by high mitotic activity, often accompanied by microvascular proliferation and pseudo-palisading necrosis. (Adapted from WHO)
Synonym	anaplastic ependymal neoplasm anaplastic ependymal tumor anaplastic ependymoma (morphologic abnormality) anaplastic ependymomas ependymoma, anaplastic ependymoma, anaplastic (morphologic abnormality) ependymoma, anaplastic, malignant ependymomas, anaplastic malignant ependymoma undifferentiated ependymal neoplasm undifferentiated ependymal tumor undifferentiated ependymoma who grade iii ependymal neoplasm who grade iii ependymal tumor
Orphanet	ORPHANET:251646
DOID	DOID:5889 DOID:5074
UMLS	C0280788
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:2) C0205769 \| myxopapillary ependymoma \| 1 C0017636 \| glioblastoma \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:81) 23492 \| CBX7 \| DISEASES 328 \| APEX1 \| DISEASES 57167 \| SALL4 \| DISEASES 3163 \| HMOX2 \| DISEASES 166 \| AES \| DISEASES 2729 \| GCLC \| DISEASES 7043 \| TGFB3 \| DISEASES 6659 \| SOX4 \| DISEASES 6662 \| SOX9 \| DISEASES 2670 \| GFAP \| DISEASES 301 \| ANXA1 \| DISEASES 3417 \| IDH1 \| DISEASES 9368 \| SLC9A3R1 \| DISEASES 6598 \| SMARCB1 \| DISEASES 421 \| ARVCF \| DISEASES 6855 \| SYP \| DISEASES 5290 \| PIK3CA \| DISEASES 4162 \| MCAM \| DISEASES 60482 \| SLC5A7 \| DISEASES 84695 \| LOXL3 \| DISEASES 7474 \| WNT5A \| DISEASES 25824 \| PRDX5 \| DISEASES 7157 \| TP53 \| DISEASES 1956 \| EGFR \| DISEASES 4851 \| NOTCH1 \| DISEASES 55294 \| FBXW7 \| DISEASES 26040 \| SETBP1 \| DISEASES 10413 \| YAP1 \| DISEASES 9965 \| FGF19 \| DISEASES 9317 \| PTER \| DISEASES 7015 \| TERT \| DISEASES 358 \| AQP1 \| DISEASES 5591 \| PRKDC \| DISEASES 4691 \| NCL \| DISEASES 6664 \| SOX11 \| DISEASES 977 \| CD151 \| DISEASES 55553 \| SOX6 \| DISEASES 9074 \| CLDN6 \| DISEASES 10215 \| OLIG2 \| DISEASES 54584 \| GNB1L \| DISEASES 3418 \| IDH2 \| DISEASES 29796 \| UQCR10 \| DISEASES 2037 \| EPB41L2 \| DISEASES 55704 \| CCDC88A \| DISEASES 23136 \| EPB41L3 \| DISEASES 2066 \| ERBB4 \| DISEASES 94241 \| TP53INP1 \| DISEASES 4771 \| NF2 \| DISEASES 2035 \| EPB41 \| DISEASES 1869 \| E2F1 \| DISEASES 5154 \| PDGFA \| DISEASES 2073 \| ERCC5 \| DISEASES 5802 \| PTPRS \| DISEASES 5079 \| PAX5 \| DISEASES 4478 \| MSN \| DISEASES 4133 \| MAP2 \| DISEASES 6663 \| SOX10 \| DISEASES 7042 \| TGFB2 \| DISEASES 2117 \| ETV3 \| DISEASES 10763 \| NES \| DISEASES 23493 \| HEY2 \| DISEASES 127003 \| C1orf194 \| DISEASES 2730 \| GCLM \| DISEASES 5728 \| PTEN \| DISEASES 546 \| ATRX \| DISEASES 25803 \| SPDEF \| DISEASES 240 \| ALOX5 \| DISEASES 2048 \| EPHB2 \| DISEASES 238 \| ALK \| DISEASES 3895 \| KTN1 \| DISEASES 7106 \| TSPAN4 \| DISEASES 5970 \| RELA \| DISEASES 55120 \| FANCL \| DISEASES 501 \| ALDH7A1 \| DISEASES 3481 \| IGF2 \| DISEASES 1029 \| CDKN2A \| DISEASES 3908 \| LAMA2 \| DISEASES 29970 \| SCHIP1 \| DISEASES 4753 \| NELL2 \| DISEASES 4193 \| MDM2 \| DISEASES 586 \| BCAT1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1715
Disease	anaplastic ependymoma
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:4) HP:0100843 \| Glioblastoma \| 1 HP:0040184 \| Oral hemorrhage \| 1 HP:0002664 \| Neoplasia \| 1 HP:0002888 \| Ependymoma \| 1

Disease ID	1715
Disease	anaplastic ependymoma
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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