PedAM

Pediatric Disease Annotations & Medicines


	amebiasis

Disease ID	618
Disease	amebiasis
Definition	Infection with any of various amebae. It is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.
Synonym	[x]amebiasis, unspecified [x]amebiasis, unspecified (disorder) [x]amoebiasis, unspecified amebiases amebiasis (disorder) amebiasis [disease/finding] amebiasis nos amebiasis nos (disorder) amebiasis, unspecified amebic infection amebic infection (disorder) amoebiases amoebiasis amoebiasis (disorder) amoebiasis nos amoebic infection amoebic infection (disorder) disease caused by endamoebidae disease caused by endamoebidae (disorder) disease due to endamoebidae disease due to endamoebidae (disorder) entamoeba histolytica infection infection caused by entamoeba histolytica infection caused by entamoeba histolytica (disorder) infection due to entameba histolytica infection due to entameba histolytica, sai infection due to entamoeba histolytica infection due to entamoeba histolytica (disorder) infection due to entamoeba histolytica, sai
DOID	DOID:9181
ICD10	ICD10CM:A06.9
UMLS	C0002438
MeSH	D000562
SNOMED-CT	SNOMEDCT_US_2016_09_01:388759003;SNOMEDCT_US_2016_09_01:105637008;SNOMEDCT_US_2016_09_01:111910009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:8) C0001175 \| acquired immunodeficiency syndrome \| 1 C0034152 \| henoch-schonlein purpura \| 1 C0747256 \| parasitic infection \| 1 C0020295 \| hydronephrosis \| 1 C0001175 \| acquired immunodeficiency syndrome (aids) \| 1 C0009319 \| colitis \| 1 C0013370 \| amebic colitis \| 1 C0013371 \| shigellosis \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:162) 3385 \| ICAM3 \| DISEASES 10598 \| AHSA1 \| DISEASES 10423 \| CDIPT \| DISEASES 1666 \| DECR1 \| DISEASES 4849 \| CNOT3 \| DISEASES 1158 \| CKM \| DISEASES 973 \| CD79A \| DISEASES 9545 \| RAB3D \| DISEASES 858 \| CAV2 \| DISEASES 6348 \| CCL3 \| DISEASES 6347 \| CCL2 \| DISEASES 6357 \| CCL13 \| DISEASES 3558 \| IL2 \| DISEASES 24145 \| PANX1 \| DISEASES 51561 \| IL23A \| DISEASES 3458 \| IFNG \| DISEASES 6678 \| SPARC \| DISEASES 3565 \| IL4 \| DISEASES 5967 \| REG1A \| DISEASES 3336 \| HSPE1 \| DISEASES 4953 \| ODC1 \| DISEASES 84057 \| MND1 \| DISEASES 56829 \| ZC3HAV1 \| DISEASES 57152 \| SLURP1 \| DISEASES 3857 \| KRT9 \| DISEASES 5199 \| CFP \| DISEASES 1258 \| CNGB1 \| DISEASES 23135 \| KDM6B \| DISEASES 1401 \| CRP \| DISEASES 1131 \| CHRM3 \| DISEASES 4608 \| MYBPH \| DISEASES 53 \| ACP2 \| DISEASES 2995 \| GYPC \| DISEASES 7097 \| TLR2 \| DISEASES 23406 \| COTL1 \| DISEASES 23239 \| PHLPP1 \| DISEASES 10552 \| ARPC1A \| DISEASES 3553 \| IL1B \| DISEASES 9424 \| KCNK6 \| DISEASES 10578 \| GNLY \| DISEASES 6774 \| STAT3 \| DISEASES 7879 \| RAB7A \| DISEASES 25824 \| PRDX5 \| DISEASES 10180 \| RBM6 \| DISEASES 6523 \| SLC5A1 \| DISEASES 5371 \| PML \| DISEASES 5211 \| PFKL \| DISEASES 57530 \| CGN \| DISEASES 52 \| ACP1 \| DISEASES 375 \| ARF1 \| DISEASES 805 \| CALM2 \| DISEASES 823 \| CAPN1 \| DISEASES 7082 \| TJP1 \| DISEASES 3192 \| HNRNPU \| DISEASES 55079 \| FEZF2 \| DISEASES 5205 \| ATP8B1 \| DISEASES 57630 \| SH3RF1 \| DISEASES 132 \| ADK \| DISEASES 808 \| CALM3 \| DISEASES 3101 \| HK3 \| DISEASES 56344 \| CABP5 \| DISEASES 51475 \| CABP2 \| DISEASES 213 \| ALB \| DISEASES 2921 \| CXCL3 \| DISEASES 201161 \| CENPV \| DISEASES 11051 \| NUDT21 \| DISEASES 3308 \| HSPA4 \| DISEASES 5968 \| REG1B \| DISEASES 25928 \| SOSTDC1 \| DISEASES 4430 \| MYO1B \| DISEASES 1938 \| EEF2 \| DISEASES 1072 \| CFL1 \| DISEASES 10221 \| TRIB1 \| DISEASES 3952 \| LEP \| DISEASES 8560 \| DEGS1 \| DISEASES 9478 \| CABP1 \| DISEASES 1129 \| CHRM2 \| DISEASES 10938 \| EHD1 \| DISEASES 3996 \| LLGL1 \| DISEASES 10611 \| PDLIM5 \| DISEASES 55 \| ACPP \| DISEASES 8454 \| CUL1 \| DISEASES 7404 \| UTY \| DISEASES 3543 \| IGLL1 \| DISEASES 10945 \| KDELR1 \| DISEASES 286753 \| TUSC5 \| DISEASES 255324 \| EPGN \| DISEASES 3953 \| LEPR \| DISEASES 2903 \| GRIN2A \| DISEASES 3320 \| HSP90AA1 \| DISEASES 25788 \| RAD54B \| DISEASES 5889 \| RAD51C \| DISEASES 200162 \| SPAG17 \| DISEASES 5781 \| PTPN11 \| DISEASES 84335 \| AKT1S1 \| DISEASES 1508 \| CTSB \| DISEASES 5962 \| RDX \| DISEASES 7177 \| TPSAB1 \| DISEASES 94241 \| TP53INP1 \| DISEASES 5213 \| PFKM \| DISEASES 6122 \| RPL3 \| DISEASES 6157 \| RPL27A \| DISEASES 54600 \| UGT1A9 \| DISEASES 79971 \| WLS \| DISEASES 954 \| ENTPD2 \| DISEASES 6204 \| RPS10 \| DISEASES 100506658 \| OCLN \| DISEASES 93979 \| CPA5 \| DISEASES 3042 \| HBM \| DISEASES 801 \| CALM1 \| DISEASES 51390 \| AIG1 \| DISEASES 26136 \| TES \| DISEASES 51592 \| TRIM33 \| DISEASES 5893 \| RAD52 \| DISEASES 6364 \| CCL20 \| DISEASES 5602 \| MAPK10 \| DISEASES 6120 \| RPE \| DISEASES 4641 \| MYO1C \| DISEASES 51150 \| SDF4 \| DISEASES 58484 \| NLRC4 \| DISEASES 3775 \| KCNK1 \| DISEASES 93183 \| PIGM \| DISEASES 912 \| CD1D \| DISEASES 4082 \| MARCKS \| DISEASES 8991 \| SELENBP1 \| DISEASES 9531 \| BAG3 \| DISEASES 1847 \| DUSP5 \| DISEASES 959 \| CD40LG \| DISEASES 51727 \| CMPK1 \| DISEASES 7295 \| TXN \| DISEASES 8718 \| TNFRSF25 \| DISEASES 1787 \| TRDMT1 \| DISEASES 10097 \| ACTR2 \| DISEASES 54620 \| FBXL19 \| DISEASES 5214 \| PFKP \| DISEASES 114899 \| C1QTNF3 \| DISEASES 5888 \| RAD51 \| DISEASES 7247 \| TSN \| DISEASES 1621 \| DBH \| DISEASES 64400 \| AKTIP \| DISEASES 81035 \| COLEC12 \| DISEASES 3098 \| HK1 \| DISEASES 3384 \| ICAM2 \| DISEASES 6147 \| RPL23A \| DISEASES 2674 \| GFRA1 \| DISEASES 1438 \| CSF2RA \| DISEASES 279 \| AMY2A \| DISEASES 7124 \| TNF \| DISEASES 5229 \| PGGT1B \| DISEASES 834 \| CASP1 \| DISEASES 389549 \| FEZF1 \| DISEASES 3586 \| IL10 \| DISEASES 4583 \| MUC2 \| DISEASES 5890 \| RAD51B \| DISEASES 8833 \| GMPS \| DISEASES 2920 \| CXCL2 \| DISEASES 100423062 \| IGLL5 \| DISEASES 9414 \| TJP2 \| DISEASES 8972 \| MGAM \| DISEASES 10577 \| NPC2 \| DISEASES 5892 \| RAD51D \| DISEASES 100302740 \| FAS-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	618
Disease	amebiasis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:5) HP:0002013 \| Emesis \| 1 HP:0000126 \| Hydronephrosis \| 1 HP:0002583 \| Colitis \| 1 HP:0100523 \| Hepatic abscess \| 1 HP:0002721 \| Immunodeficiency \| 1

Disease ID	618
Disease	amebiasis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:15) C1510428 \| cerebral abscesses C0701815 \| hyperchromic anemia C0267166 \| gastroduodenitis C0221014 \| secondary amyloidosis C0151594 \| bloody diarrhea C0042850 \| vitamin b complex deficiency C0038463 \| strongyloidiasis C0037285 \| skin manifestations C0037074 \| sigmoiditis C0031154 \| peritonitis C0019204 \| hepatic carcinoma C0019158 \| hepatitis C0008526 \| choroiditis C0007137 \| squamous cell carcinoma C0000727 \| acute abdomen
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:1)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1137101	25516614	3953	LEPR	umls:C0002438	BeFree	Humans with the Q223R leptin receptor mutation have increased susceptibility to amebiasis, but the mechanism has been unclear.	0.000542884	2015	LEPR	1	65592830	A	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0002438	tinidazole	D014011	19387-91-8	amebiasis	MESH:D000562	therapeutic	7123

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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