PedAM

Pediatric Disease Annotations & Medicines


	allergic conjunctivitis

Disease ID	1259
Disease	allergic conjunctivitis
Definition	Conjunctivitis due to hypersensitivity to various allergens.
Synonym	allergic conjunctivitides allergic conjunctivitis (disorder) atopic conjunctivitides atopic conjunctivitis atopic conjunctivitis (disorder) conjunctivitides, allergic conjunctivitides, atopic conjunctivitis, allergic conjunctivitis, allergic [disease/finding] conjunctivitis, atopic
DOID	DOID:11204
UMLS	C0009766
MeSH	D003233
SNOMED-CT	SNOMEDCT_US_2016_09_01:473460002;SNOMEDCT_US_2016_09_01:231854006
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:7) C0035455 \| rhinitis \| 3 C0004096 \| asthma \| 2 C2607914 \| allergic rhinitis \| 2 C0028754 \| obesity \| 1 C0314719 \| dry eye \| 1 C0042164 \| uveitis \| 1 C0040592 \| trachoma \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:117) 4616 \| GADD45B \| DISEASES 4282 \| MIF \| DISEASES 140679 \| SLC32A1 \| DISEASES 6361 \| CCL17 \| DISEASES 973 \| CD79A \| DISEASES 6369 \| CCL24 \| DISEASES 8288 \| EPX \| DISEASES 6347 \| CCL2 \| DISEASES 3558 \| IL2 \| DISEASES 3458 \| IFNG \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 2908 \| NR3C1 \| DISEASES 9173 \| IL1RL1 \| DISEASES 1179 \| CLCA1 \| DISEASES 51426 \| POLK \| DISEASES 8744 \| TNFSF9 \| DISEASES 970 \| CD70 \| DISEASES 1236 \| CCR7 \| DISEASES 54567 \| DLL4 \| DISEASES 1215 \| CMA1 \| DISEASES 59340 \| HRH4 \| DISEASES 301 \| ANXA1 \| DISEASES 79074 \| C2orf49 \| DISEASES 3569 \| IL6 \| DISEASES 7097 \| TLR2 \| DISEASES 8482 \| SEMA7A \| DISEASES 4016 \| LOXL1 \| DISEASES 8989 \| TRPA1 \| DISEASES 3553 \| IL1B \| DISEASES 2208 \| FCER2 \| DISEASES 941 \| CD80 \| DISEASES 80725 \| SRCIN1 \| DISEASES 3383 \| ICAM1 \| DISEASES 3687 \| ITGAX \| DISEASES 2854 \| GPR32 \| DISEASES 2206 \| MS4A2 \| DISEASES 7292 \| TNFSF4 \| DISEASES 57105 \| CYSLTR2 \| DISEASES 729230 \| CCR2 \| DISEASES 5731 \| PTGER1 \| DISEASES 6352 \| CCL5 \| DISEASES 7412 \| VCAM1 \| DISEASES 213 \| ALB \| DISEASES 7098 \| TLR3 \| DISEASES 1437 \| CSF2 \| DISEASES 6778 \| STAT6 \| DISEASES 6356 \| CCL11 \| DISEASES 6037 \| RNASE3 \| DISEASES 5734 \| PTGER4 \| DISEASES 6036 \| RNASE2 \| DISEASES 3688 \| ITGB1 \| DISEASES 3596 \| IL13 \| DISEASES 9655 \| SOCS5 \| DISEASES 3627 \| CXCL10 \| DISEASES 6373 \| CXCL11 \| DISEASES 84868 \| HAVCR2 \| DISEASES 80381 \| CD276 \| DISEASES 6863 \| TAC1 \| DISEASES 64332 \| NFKBIZ \| DISEASES 3714 \| JAG2 \| DISEASES 29933 \| GPR132 \| DISEASES 9021 \| SOCS3 \| DISEASES 6401 \| SELE \| DISEASES 11251 \| PTGDR2 \| DISEASES 85480 \| TSLP \| DISEASES 7100 \| TLR5 \| DISEASES 2358 \| FPR2 \| DISEASES 27159 \| CHIA \| DISEASES 6590 \| SLPI \| DISEASES 11255 \| HRH3 \| DISEASES 3605 \| IL17A \| DISEASES 5733 \| PTGER3 \| DISEASES 10803 \| CCR9 \| DISEASES 6364 \| CCL20 \| DISEASES 83881 \| MIXL1 \| DISEASES 23418 \| CRB1 \| DISEASES 912 \| CD1D \| DISEASES 2312 \| FLG \| DISEASES 8732 \| RNGTT \| DISEASES 4803 \| NGF \| DISEASES 2316 \| FLNA \| DISEASES 4791 \| NFKB2 \| DISEASES 51013 \| EXOSC1 \| DISEASES 958 \| CD40 \| DISEASES 10800 \| CYSLTR1 \| DISEASES 5320 \| PLA2G2A \| DISEASES 50943 \| FOXP3 \| DISEASES 3604 \| TNFRSF9 \| DISEASES 7293 \| TNFRSF4 \| DISEASES 1992 \| SERPINB1 \| DISEASES 90865 \| IL33 \| DISEASES 64109 \| CRLF2 \| DISEASES 26278 \| SACS \| DISEASES 6370 \| CCL25 \| DISEASES 838 \| CASP5 \| DISEASES 3965 \| LGALS9 \| DISEASES 3269 \| HRH1 \| DISEASES 94025 \| MUC16 \| DISEASES 5970 \| RELA \| DISEASES 23308 \| ICOSLG \| DISEASES 50489 \| CD207 \| DISEASES 23066 \| CAND2 \| DISEASES 3384 \| ICAM2 \| DISEASES 6915 \| TBXA2R \| DISEASES 8399 \| PLA2G10 \| DISEASES 7124 \| TNF \| DISEASES 4615 \| MYD88 \| DISEASES 1154 \| CISH \| DISEASES 3586 \| IL10 \| DISEASES 573 \| BAG1 \| DISEASES 51428 \| DDX41 \| DISEASES 4168 \| MCF2 \| DISEASES 83695 \| RHNO1 \| DISEASES 1232 \| CCR3 \| DISEASES 3684 \| ITGAM \| DISEASES 387521 \| TMEM189 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1259
Disease	allergic conjunctivitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:9) HP:0012384 \| Nasal inflammation \| 3 HP:0002099 \| Asthma \| 2 HP:0003193 \| Allergic rhinitis \| 2 HP:0000989 \| pruritis \| 2 HP:0012393 \| Allergy \| 1 HP:0000559 \| Corneal scarring \| 1 HP:0000554 \| Uveitis \| 1 HP:0012375 \| Chemosis \| 1 HP:0001513 \| Obesity \| 1

Disease ID	1259
Disease	allergic conjunctivitis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:3) C0033774 \| itching \| 16 C0858919 \| conjunctival redness \| 1 C0231918 \| nasal symptoms \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:1)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs376158	26011970	50943	FOXP3	umls:C0009766	BeFree	Relationship between Foxp3-3279 (rs376158) polymorphism and dust mite allergic conjunctivitis.	0.000271442	2015	NA	X	138098411	T	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0009766	phenylephrine	D010656	59-42-7	conjunctivitis, allergic	MESH:D003233	marker/mechanism	12199969
C0009766	phenytoin	D010672	57-41-0	conjunctivitis, allergic	MESH:D003233	marker/mechanism	7439205
C0009766	zafirlukast	C062735	107753-78-6	conjunctivitis, allergic	MESH:D003233	therapeutic	15351322

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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