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PedAM

Pediatric Disease Annotations & Medicines



   alk-positive anaplastic large cell lymphoma
  

Disease ID 1712
Disease alk-positive anaplastic large cell lymphoma
Definition
A T-cell peripheral lymphoma composed of usually large, pleomorphic, CD30 positive T-lymphocytes with abundant cytoplasm characterized by the presence of a translocation involving the ALK gene and expression of ALK fusion protein. Most patients present with peripheral and/or abdominal lymphadenopathy, and often have advanced disease and extranodal involvement.
Synonym
alcl, alk+
alkoma
anaplastic large cell lymphoma, alk-positive
Orphanet
UMLS
C1332079
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:4)
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:1)
ALK  |  238  |  ORPHANET
Inferring Gene(Waiting for update.)
Text Mined Gene(Waiting for update.)
Locus
Symbol | Locus(Total Locus:1)
ALK  |  2p23.2-p23.1
Disease ID 1712
Disease alk-positive anaplastic large cell lymphoma
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:2)
Disease ID 1712
Disease alk-positive anaplastic large cell lymphoma
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:0)
(Waiting for update.)
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)