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Pediatric Disease Annotations & Medicines



   alcoholic hepatitis
  

Disease ID 1045
Disease alcoholic hepatitis
Definition
INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.
Synonym
ah - alcoholic hepatitis
alcohol hepatitis
alcoholic hepatitis (disorder)
alcoholics hepatitis
hepatitis alcohol
hepatitis alcoholic
hepatitis, alcoholic
hepatitis, alcoholic [disease/finding]
DOID
UMLS
C0019187
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:18)
C0023895  |  liver disease  |  4
C0023890  |  cirrhosis  |  3
C0001973  |  alcoholism  |  2
C0442874  |  neuropathy  |  1
C0023895  |  liver diseases  |  1
C0014868  |  esophagitis  |  1
C0020538  |  hypertension  |  1
C0029132  |  optic neuropathy  |  1
C0020541  |  portal hypertension  |  1
C0024299  |  lymphoma  |  1
C0004030  |  aspergillosis  |  1
C0085293  |  hepatitis e  |  1
C0241910  |  autoimmune hepatitis  |  1
C0026946  |  fungal infections  |  1
C0026946  |  fungal infection  |  1
C0019158  |  hepatitis  |  1
C0023891  |  alcoholic cirrhosis  |  1
C0343386  |  clostridium difficile infection  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:2)
TNF  |  7124  |  CTD_human
CCL5  |  6352  |  CTD_human
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:2)
3586  |  IL10  |  infer
7124  |  TNF  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:155)
84699  |  CREB3L3  |  DISEASES
7132  |  TNFRSF1A  |  DISEASES
124  |  ADH1A  |  DISEASES
25984  |  KRT23  |  DISEASES
23411  |  SIRT1  |  DISEASES
80339  |  PNPLA3  |  DISEASES
3929  |  LBP  |  DISEASES
7076  |  TIMP1  |  DISEASES
1666  |  DECR1  |  DISEASES
973  |  CD79A  |  DISEASES
6348  |  CCL3  |  DISEASES
4353  |  MPO  |  DISEASES
6347  |  CCL2  |  DISEASES
230  |  ALDOC  |  DISEASES
6372  |  CXCL6  |  DISEASES
84649  |  DGAT2  |  DISEASES
3458  |  IFNG  |  DISEASES
4188  |  MDFI  |  DISEASES
3565  |  IL4  |  DISEASES
335  |  APOA1  |  DISEASES
7276  |  TTR  |  DISEASES
4360  |  MRC1  |  DISEASES
51569  |  UFM1  |  DISEASES
84329  |  HVCN1  |  DISEASES
2678  |  GGT1  |  DISEASES
968  |  CD68  |  DISEASES
3630  |  INS  |  DISEASES
5894  |  RAF1  |  DISEASES
55821  |  ALLC  |  DISEASES
1571  |  CYP2E1  |  DISEASES
3021  |  H3F3B  |  DISEASES
1401  |  CRP  |  DISEASES
1116  |  CHI3L1  |  DISEASES
23175  |  LPIN1  |  DISEASES
6610  |  SMPD2  |  DISEASES
3569  |  IL6  |  DISEASES
7097  |  TLR2  |  DISEASES
10068  |  IL18BP  |  DISEASES
4659  |  PPP1R12A  |  DISEASES
7450  |  VWF  |  DISEASES
217  |  ALDH2  |  DISEASES
3552  |  IL1A  |  DISEASES
3553  |  IL1B  |  DISEASES
1356  |  CP  |  DISEASES
3383  |  ICAM1  |  DISEASES
127  |  ADH4  |  DISEASES
5244  |  ABCB4  |  DISEASES
84920  |  ALG10  |  DISEASES
56938  |  ARNTL2  |  DISEASES
51411  |  BIN2  |  DISEASES
6652  |  SORD  |  DISEASES
3934  |  LCN2  |  DISEASES
2746  |  GLUD1  |  DISEASES
23576  |  DDAH1  |  DISEASES
114  |  ADCY8  |  DISEASES
6296  |  ACSM3  |  DISEASES
267  |  AMFR  |  DISEASES
6352  |  CCL5  |  DISEASES
3856  |  KRT8  |  DISEASES
248  |  ALPI  |  DISEASES
3577  |  CXCR1  |  DISEASES
8320  |  EOMES  |  DISEASES
213  |  ALB  |  DISEASES
6374  |  CXCL5  |  DISEASES
84315  |  MON1A  |  DISEASES
6690  |  SPINK1  |  DISEASES
5479  |  PPIB  |  DISEASES
23179  |  RGL1  |  DISEASES
29  |  ABR  |  DISEASES
84342  |  COG8  |  DISEASES
125  |  ADH1B  |  DISEASES
2147  |  F2  |  DISEASES
144245  |  ALG10B  |  DISEASES
3661  |  IRF3  |  DISEASES
836  |  CASP3  |  DISEASES
55236  |  UBA6  |  DISEASES
1831  |  TSC22D3  |  DISEASES
30835  |  CD209  |  DISEASES
3579  |  CXCR2  |  DISEASES
6014  |  RIT2  |  DISEASES
55  |  ACPP  |  DISEASES
51330  |  TNFRSF12A  |  DISEASES
3855  |  KRT7  |  DISEASES
50616  |  IL22  |  DISEASES
7850  |  IL1R2  |  DISEASES
6401  |  SELE  |  DISEASES
5142  |  PDE4B  |  DISEASES
151888  |  BTLA  |  DISEASES
226  |  ALDOA  |  DISEASES
2309  |  FOXO3  |  DISEASES
89910  |  UBE3B  |  DISEASES
84706  |  GPT2  |  DISEASES
224  |  ALDH3A2  |  DISEASES
5562  |  PRKAA1  |  DISEASES
355  |  FAS  |  DISEASES
2074  |  ERCC6  |  DISEASES
3240  |  HP  |  DISEASES
79876  |  UBA5  |  DISEASES
6525  |  SMTN  |  DISEASES
2526  |  FUT4  |  DISEASES
6364  |  CCL20  |  DISEASES
9332  |  CD163  |  DISEASES
6905  |  TBCE  |  DISEASES
3020  |  H3F3A  |  DISEASES
6993  |  DYNLT1  |  DISEASES
356  |  FASLG  |  DISEASES
336  |  APOA2  |  DISEASES
51506  |  UFC1  |  DISEASES
284486  |  THEM5  |  DISEASES
23376  |  UFL1  |  DISEASES
2805  |  GOT1  |  DISEASES
959  |  CD40LG  |  DISEASES
55361  |  PI4K2A  |  DISEASES
1791  |  DNTT  |  DISEASES
11124  |  FAF1  |  DISEASES
11093  |  ADAMTS13  |  DISEASES
79717  |  PPCS  |  DISEASES
6429  |  SRSF4  |  DISEASES
7099  |  TLR4  |  DISEASES
5696  |  PSMB8  |  DISEASES
7133  |  TNFRSF1B  |  DISEASES
3105  |  HLA-A  |  DISEASES
10537  |  UBD  |  DISEASES
219  |  ALDH1B1  |  DISEASES
444  |  ASPH  |  DISEASES
3030  |  HADHA  |  DISEASES
402682  |  UFSP1  |  DISEASES
3875  |  KRT18  |  DISEASES
51070  |  NOSIP  |  DISEASES
250  |  ALPP  |  DISEASES
51520  |  LARS  |  DISEASES
130  |  ADH6  |  DISEASES
2875  |  GPT  |  DISEASES
6696  |  SPP1  |  DISEASES
3965  |  LGALS9  |  DISEASES
2919  |  CXCL1  |  DISEASES
174  |  AFP  |  DISEASES
728441  |  GGT2  |  DISEASES
7018  |  TF  |  DISEASES
501  |  ALDH7A1  |  DISEASES
2641  |  GCG  |  DISEASES
115677  |  NOSTRIN  |  DISEASES
22893  |  BAHD1  |  DISEASES
7124  |  TNF  |  DISEASES
4615  |  MYD88  |  DISEASES
2886  |  GRB7  |  DISEASES
3276  |  PRMT1  |  DISEASES
63924  |  CIDEC  |  DISEASES
834  |  CASP1  |  DISEASES
3586  |  IL10  |  DISEASES
6434  |  TRA2B  |  DISEASES
79813  |  EHMT1  |  DISEASES
131  |  ADH7  |  DISEASES
2920  |  CXCL2  |  DISEASES
84823  |  LMNB2  |  DISEASES
Locus(Waiting for update.)
Disease ID 1045
Disease alcoholic hepatitis
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:10)
HP:0001394  |  Hepatic cirrhosis  |  3
HP:0001409  |  Portal hypertension  |  1
HP:0002665  |  Lymphoma  |  1
HP:0002239  |  Gastrointestinal hemorrhage  |  1
HP:0002584  |  Intestinal hemorrhage  |  1
HP:0000822  |  Hypertension  |  1
HP:0100633  |  Inflammation of the esophagus  |  1
HP:0100806  |  Sepsis  |  1
HP:0012115  |  Liver inflammation  |  1
HP:0001138  |  Damaged optic nerve  |  1
Disease ID 1045
Disease alcoholic hepatitis
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:2)
C0023890  |  cirrhosis  |  3
C0948600  |  organ failure  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:1)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0019187theophyllineD01380658-55-9hepatitis, alcoholicMESH:D006519therapeutic20578267
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)