PedAM

Pediatric Disease Annotations & Medicines


	alcohol dependence

Disease ID	508
Disease	alcohol dependence
Definition	A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
Synonym	(alcohol dependence syndrome [including alcoholism]) or (alcohol problem drinking) (alcohol dependence syndrome [including alcoholism]) or (alcohol problem drinking) (disorder) [x]alcohol addiction [x]chronic alcoholism [x]dipsomania [x]mental and behavioral disorders due to use of alcohol: dependence syndrome [x]mental and behavioral disorders due to use of alcohol: dependence syndrome (disorder) [x]mental and behavioural disorders due to use of alcohol: dependence syndrome abuse alcohol alcoholism addiction alcohol addiction, alcohol alcohol abuse alcoholism alcohol addiction alcohol dependence (disorder) alcohol dependence syndrome alcohol dependence syndrome (& [dipsomania]) alcohol dependence syndrome (& [dipsomania]) (disorder) alcohol dependence syndrome nos alcohol dependence syndrome nos (disorder) alcohol dependences alcohol dependency alcohol problem drinking alcoholic intox chronic alcoholic intoxication, chronic alcoholism alcoholism (disorder) alcoholism [disease/finding] alcoholism and alcohol abuse alcoholism chronic alcoholism chronic disorders alcoholism disorders alcoholism, nos alcoholism/alcohol abuse alcoholisms chronic alcohol abuse chronic alcoholic intoxication chronic alcoholism chronic alcoholism (& [dipsomania]) chronic alcoholism (& [dipsomania]) (disorder) chronic alcoholism (disorder) chronic alcoholism [ambiguous] chronic alcoholism nos chronic alcoholism nos (disorder) dependence alcoholism alcohol dependence, alcohol dipsomania dipsomania (finding) disorder alcoholism intoxication, chronic alcoholic persistent alcohol abuse persistent alcohol abuse (disorder) unspecified chronic alcoholism unspecified chronic alcoholism (disorder)
OMIM	OMIM:103780
DOID	DOID:0050741
UMLS	C0001973
MeSH	D000437
SNOMED-CT	SNOMEDCT_US_2016_09_01:284591009;SNOMEDCT_US_2016_09_01:66590003;SNOMEDCT_US_2016_09_01:7200002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:40) C0003467 \| anxiety \| 11 C0011570 \| depression \| 10 C0003469 \| anxiety disorder \| 6 C0003469 \| anxiety disorders \| 5 C0004936 \| mental disorders \| 5 C0023895 \| liver disease \| 5 C1510472 \| drug dependence \| 4 C0679466 \| cognitive deficits \| 4 C0038436 \| posttraumatic stress disorder \| 3 C0041696 \| major depression \| 3 C0041696 \| major depressive disorder \| 2 C0162429 \| malnourished \| 2 C0009171 \| cocaine abuse \| 2 C0011847 \| diabetes \| 2 C0242350 \| erectile dysfunction \| 2 C0023890 \| cirrhosis \| 2 C0001973 \| alcoholism \| 2 C0028754 \| obesity \| 2 C0149654 \| conduct disorder \| 2 C0005586 \| bipolar disorder \| 2 C0011849 \| diabetes mellitus \| 1 C0038436 \| post-traumatic stress disorder \| 1 C0023890 \| liver cirrhosis \| 1 C0442874 \| neuropathy \| 1 C0036349 \| paranoid schizophrenia \| 1 C0030783 \| pellagra \| 1 C0242379 \| lung cancer \| 1 C0600427 \| cocaine dependence \| 1 C0033975 \| psychoses \| 1 C0041696 \| unipolar depression \| 1 C0011860 \| type 2 diabetes mellitus \| 1 C0036341 \| schizophrenia \| 1 C0001622 \| hypercortisolism \| 1 C0002020 \| alexithymia \| 1 C0259749 \| autonomic neuropathy \| 1 C0011860 \| type 2 diabetes \| 1 C0033975 \| psychotic disorder \| 1 C0014544 \| seizure disorder \| 1 C0023895 \| liver diseases \| 1 C0031212 \| personality disorders \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:41) LHB \| 3972 \| CTD_human NPY2R \| 4887 \| CTD_human TACR3 \| 6870 \| CTD_human SNCA \| 6622 \| CTD_human SLC6A4 \| 6532 \| CTD_human PKNOX2 \| 63876 \| GWASCAT FSHB \| 2488 \| CTD_human NPY \| 4852 \| CTD_human PDYN \| 5173 \| CTD_human GABRA2 \| 2555 \| CTD_human COMT \| 1312 \| CTD_human CYP2E1 \| 1571 \| CTD_human GATA4 \| 2626 \| CTD_human HTR2A \| 3356 \| CTD_human CHRNA3 \| 1136 \| CTD_human GABRG2 \| 2566 \| CTD_human CHRNA5 \| 1138 \| CTD_human RCBTB1 \| 55213 \| CTD_human TF \| 7018 \| CTD_human GGT1 \| 2678 \| CTD_human ALDH2 \| 217 \| CLINVAR;CTD_human;GWASCAT OPRM1 \| 4988 \| CTD_human PDE4B \| 5142 \| CTD_human ADH1B \| 125 \| CTD_human;GWASCAT ADH1C \| 126 \| CTD_human ARL15 \| 54622 \| GWASCAT UTP20 \| 27340 \| GWASCAT SHBG \| 6462 \| CTD_human CDK20 \| 23552 \| CTD_human SERINC2 \| 347735 \| GWASCAT TACR1 \| 6869 \| CTD_human TAS2R38 \| 5726 \| CTD_human C15orf32 \| 145858 \| GWASCAT PECR \| 55825 \| GWASCAT GABBR1 \| 2550 \| CTD_human TAS2R16 \| 50833 \| CTD_human CCKAR \| 886 \| CTD_human GHSR \| 2693 \| CTD_human TBX19 \| 9095 \| CTD_human GPHN \| 10243 \| CTD_human MBNL2 \| 10150 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:538) 4915 \| NTRK2 \| infer 124 \| ADH1A \| infer 125 \| ADH1B \| infer 126 \| ADH1C \| infer 128 \| ADH5 \| infer 130 \| ADH6 \| infer 131 \| ADH7 \| infer 217 \| ALDH2 \| infer 831 \| CAST \| infer 885 \| CCK \| infer 886 \| CCKAR \| infer 887 \| CCKBR \| infer 1268 \| CNR1 \| infer 1394 \| CRHR1 \| infer 1813 \| DRD2 \| infer 1814 \| DRD3 \| infer 51752 \| ERAP1 \| infer 2099 \| ESR1 \| infer 2554 \| GABRA1 \| infer 2555 \| GABRA2 \| infer 2559 \| GABRA6 \| infer 2560 \| GABRB1 \| infer 2565 \| GABRG1 \| infer 2566 \| GABRG2 \| infer 2567 \| GABRG3 \| infer 2899 \| GRIK3 \| infer 3350 \| HTR1A \| infer 3351 \| HTR1B \| infer 3356 \| HTR2A \| infer 4852 \| NPY \| infer 4988 \| OPRM1 \| infer 55825 \| PECR \| infer 5521 \| PPP2R2B \| infer 6506 \| SLC1A2 \| infer 6580 \| SLC22A1 \| infer 6530 \| SLC6A2 \| infer 6532 \| SLC6A4 \| infer 374879 \| ZNF699 \| infer 109 \| ADCY3 \| infer 10550 \| ARL6IP5 \| infer 833 \| CARS \| infer 387707 \| CC2D2B \| infer 1363 \| CPE \| infer 58511 \| DNASE2B \| infer 2626 \| GATA4 \| infer 2915 \| GRM5 \| infer 3400 \| ID4 \| infer 4676 \| NAP1L4 \| infer 114879 \| OSBPL5 \| infer 7262 \| PHLDA2 \| infer 63876 \| PKNOX2 \| infer 9467 \| SH3BP5 \| infer 6555 \| SLC10A2 \| infer 5002 \| SLC22A18 \| infer 677833 \| SNORA54 \| infer 23345 \| SYNE1 \| infer 27010 \| TPK1 \| infer 150000 \| ABCC13 \| infer 25 \| ABL1 \| infer 35 \| ACADS \| infer 1636 \| ACE \| infer 58 \| ACTA1 \| infer 88 \| ACTN2 \| infer 89 \| ACTN3 \| infer 81 \| ACTN4 \| infer 100 \| ADA \| infer 11093 \| ADAMTS13 \| infer 11095 \| ADAMTS8 \| infer 116 \| ADCYAP1 \| infer 127 \| ADH4 \| infer 146 \| ADRA1D \| infer 154 \| ADRB2 \| infer 84632 \| AFAP1L2 \| infer 55326 \| AGPAT5 \| infer 9255 \| AIMP1 \| infer 1645 \| AKR1C1 \| infer 8644 \| AKR1C3 \| infer 1109 \| AKR1C4 \| infer 210 \| ALAD \| infer 216 \| ALDH1A1 \| infer 7915 \| ALDH5A1 \| infer 80216 \| ALPK1 \| infer 287 \| ANK2 \| infer 255239 \| ANKK1 \| infer 23294 \| ANKS1A \| infer 55435 \| AP1AR \| infer 348 \| APOE \| infer 367 \| AR \| infer 55843 \| ARHGAP15 \| infer 406 \| ARNTL \| infer 56938 \| ARNTL2 \| infer 57561 \| ARRDC3 \| infer 410 \| ARSA \| infer 79642 \| ARSJ \| infer 443 \| ASPA \| infer 100151642 \| ATG12P1 \| infer 540 \| ATP7B \| infer 6315 \| ATXN8OS \| infer 594 \| BCKDHB \| infer 56898 \| BDH2 \| infer 624 \| BDKRB2 \| infer 627 \| BDNF \| infer 658 \| BMPR1B \| infer 664 \| BNIP3 \| infer 118663 \| BTBD16 \| infer 699 \| BUB1 \| infer 145858 \| C15orf32 \| infer 401152 \| C4orf3 \| infer 775 \| CACNA1C \| infer 8912 \| CACNA1H \| infer 783 \| CACNB2 \| infer 817 \| CAMK2D \| infer 814 \| CAMK4 \| infer 23473 \| CAPN7 \| infer 839 \| CASP6 \| infer 859 \| CAV3 \| infer 147372 \| CCBE1 \| infer 84692 \| CCDC54 \| infer 904 \| CCNT1 \| infer 963 \| CD53 \| infer 1012 \| CDH13 \| infer 55755 \| CDK5RAP2 \| infer 1062 \| CENPE \| infer 3426 \| CFI \| infer 1123 \| CHN1 \| infer 8646 \| CHRD \| infer 1128 \| CHRM1 \| infer 1129 \| CHRM2 \| infer 1134 \| CHRNA1 \| infer 1135 \| CHRNA2 \| infer 1136 \| CHRNA3 \| infer 1137 \| CHRNA4 \| infer 1138 \| CHRNA5 \| infer 1143 \| CHRNB4 \| infer 1144 \| CHRND \| infer 150468 \| CKAP2L \| infer 1183 \| CLCN4 \| infer 9575 \| CLOCK \| infer 168975 \| CNBD1 \| infer 1258 \| CNGB1 \| infer 152330 \| CNTN4 \| infer 22837 \| COBLL1 \| infer 1277 \| COL1A1 \| infer 84570 \| COL25A1 \| infer 1284 \| COL4A2 \| infer 1285 \| COL4A3 \| infer 1291 \| COL6A1 \| infer 8292 \| COLQ \| infer 1312 \| COMT \| infer 10815 \| CPLX1 \| infer 1385 \| CREB1 \| infer 1393 \| CRHBP \| infer 1408 \| CRY2 \| infer 55790 \| CSGALNACT1 \| infer 114784 \| CSMD2 \| infer 80034 \| CSRNP3 \| infer 1491 \| CTH \| infer 1496 \| CTNNA2 \| infer 51076 \| CUTC \| infer 80319 \| CXXC4 \| infer 360168 \| CYCSP12 \| infer 1571 \| CYP2E1 \| infer 113612 \| CYP2U1 \| infer 1601 \| DAB2 \| infer 1630 \| DCC \| infer 1634 \| DCN \| infer 80821 \| DDHD1 \| infer 8528 \| DDO \| infer 1719 \| DHFR \| infer 23405 \| DICER1 \| infer 27123 \| DKK2 \| infer 1739 \| DLG1 \| infer 1742 \| DLG4 \| infer 1758 \| DMP1 \| infer 1794 \| DOCK2 \| infer 1812 \| DRD1 \| infer 1815 \| DRD4 \| infer 57453 \| DSCAML1 \| infer 1834 \| DSPP \| infer 1780 \| DYNC1I1 \| infer 9521 \| EEF1E1 \| infer 114327 \| EFHC1 \| infer 1950 \| EGF \| infer 23301 \| EHBP1 \| infer 339799 \| EIF3FP3 \| infer 60481 \| ELOVL5 \| infer 79071 \| ELOVL6 \| infer 133418 \| EMB \| infer 2028 \| ENPEP \| infer 9583 \| ENTPD4 \| infer 57089 \| ENTPD7 \| infer 2045 \| EPHA7 \| infer 23085 \| ERC1 \| infer 26059 \| ERC2 \| infer 2072 \| ERCC4 \| infer 57471 \| ERMN \| infer 2139 \| EYA2 \| infer 2166 \| FAAH \| infer 2169 \| FABP2 \| infer 11124 \| FAF1 \| infer 2184 \| FAH \| infer 9855 \| FARP2 \| infer 10667 \| FARS2 \| infer 2199 \| FBLN2 \| infer 10516 \| FBLN5 \| infer 2201 \| FBN2 \| infer 2222 \| FDFT1 \| infer 9637 \| FEZ2 \| infer 2250 \| FGF5 \| infer 2272 \| FHIT \| infer 2289 \| FKBP5 \| infer 2317 \| FLNB \| infer 2322 \| FLT3 \| infer 2324 \| FLT4 \| infer 2303 \| FOXC2 \| infer 2534 \| FYN \| infer 2561 \| GABRB2 \| infer 2562 \| GABRB3 \| infer 2570 \| GABRR2 \| infer 2571 \| GAD1 \| infer 2572 \| GAD2 \| infer 10912 \| GADD45G \| infer 51083 \| GAL \| infer 2587 \| GALR1 \| infer 8811 \| GALR2 \| infer 8484 \| GALR3 \| infer 51738 \| GHRL \| infer 2693 \| GHSR \| infer 2736 \| GLI2 \| infer 2739 \| GLO1 \| infer 8001 \| GLRA3 \| infer 2743 \| GLRB \| infer 2746 \| GLUD1 \| infer 8833 \| GMPS \| infer 2778 \| GNAS \| infer 100130060 \| GNPATP \| infer 2805 \| GOT1 \| infer 2897 \| GRIK1 \| infer 2900 \| GRIK4 \| infer 2902 \| GRIN1 \| infer 2903 \| GRIN2A \| infer 2904 \| GRIN2B \| infer 2869 \| GRK5 \| infer 2914 \| GRM4 \| infer 2917 \| GRM7 \| infer 2918 \| GRM8 \| infer 2932 \| GSK3B \| infer 79807 \| GSTCD \| infer 2954 \| GSTZ1 \| infer 149699 \| GTSF1L \| infer 3000 \| GUCY2D \| infer 9555 \| H2AFY \| infer 23498 \| HAAO \| infer 3033 \| HADH \| infer 348980 \| HCN1 \| infer 23072 \| HECW1 \| infer 391723 \| HELT \| infer 3081 \| HGD \| infer 3092 \| HIP1 \| infer 3096 \| HIVEP1 \| infer 3131 \| HLF \| infer 3159 \| HMGA1 \| infer 3176 \| HNMT \| infer 3181 \| HNRNPA2B1 \| infer 9456 \| HOMER1 \| infer 9455 \| HOMER2 \| infer 3358 \| HTR2C \| infer 3359 \| HTR3A \| infer 9177 \| HTR3B \| infer 3620 \| IDO1 \| infer 3480 \| IGF1R \| infer 3552 \| IL1A \| infer 3553 \| IL1B \| infer 3554 \| IL1R1 \| infer 3557 \| IL1RN \| infer 3617 \| IMPG1 \| infer 57117 \| INTS12 \| infer 3394 \| IRF8 \| infer 3673 \| ITGA2 \| infer 3689 \| ITGB2 \| infer 162073 \| ITPRIPL2 \| infer 3738 \| KCNA3 \| infer 3751 \| KCND2 \| infer 3756 \| KCNH1 \| infer 3778 \| KCNMA1 \| infer 57179 \| KIAA1191 \| infer 23303 \| KIF13B \| infer 3800 \| KIF5C \| infer 7071 \| KLF10 \| infer 3848 \| KRT1 \| infer 643858 \| KRT18P30 \| infer 51350 \| KRT76 \| infer 3912 \| LAMB1 \| infer 51574 \| LARP7 \| infer 253558 \| LCLAT1 \| infer 51176 \| LEF1 \| infer 26468 \| LHX6 \| infer 79888 \| LPCAT1 \| infer 345193 \| LRIT3 \| infer 4036 \| LRP2 \| infer 10128 \| LRPPRC \| infer 4046 \| LSP1 \| infer 130576 \| LYPD6B \| infer 84445 \| LZTS2 \| infer 140733 \| MACROD2 \| infer 4085 \| MAD2L1 \| infer 4126 \| MANBA \| infer 4128 \| MAOA \| infer 4129 \| MAOB \| infer 4293 \| MAP3K9 \| infer 4143 \| MAT1A \| infer 4148 \| MATN3 \| infer 4153 \| MBL2 \| infer 10150 \| MBNL2 \| infer 55784 \| MCTP2 \| infer 51072 \| MEMO1 \| infer 131572 \| MESTP4 \| infer 57721 \| METTL14 \| infer 64863 \| METTL4 \| infer 4249 \| MGAT5 \| infer 11343 \| MGLL \| infer 84953 \| MICALCL \| infer 27249 \| MMADHC \| infer 23531 \| MMD \| infer 4318 \| MMP9 \| infer 55686 \| MREG \| infer 359766 \| MRPS21P2 \| infer 4436 \| MSH2 \| infer 4524 \| MTHFR \| infer 4528 \| MTIF2 \| infer 4552 \| MTRR \| infer 9788 \| MTSS1 \| infer 4588 \| MUC6 \| infer 4589 \| MUC7 \| infer 4636 \| MYL5 \| infer 23026 \| MYO16 \| infer 4646 \| MYO6 \| infer 4647 \| MYO7A \| infer 51778 \| MYOZ2 \| infer 65065 \| NBEAL1 \| infer 4684 \| NCAM1 \| infer 4685 \| NCAM2 \| infer 8202 \| NCOA3 \| infer 9348 \| NDST3 \| infer 64579 \| NDST4 \| infer 4747 \| NEFL \| infer 63973 \| NEUROG2 \| infer 4783 \| NFIL3 \| infer 4790 \| NFKB1 \| infer 22871 \| NLGN1 \| infer 4842 \| NOS1 \| infer 4862 \| NPAS2 \| infer 64067 \| NPAS3 \| infer 10828 \| NPM1P19 \| infer 255743 \| NPNT \| infer 10718 \| NRG3 \| infer 8829 \| NRP1 \| infer 9378 \| NRXN1 \| infer 9369 \| NRXN3 \| infer 4916 \| NTRK3 \| infer 23620 \| NTSR2 \| infer 26747 \| NUFIP1 \| infer 11249 \| NXPH2 \| infer 80207 \| OPA3 \| infer 94233 \| OPN4 \| infer 4986 \| OPRK1 \| infer 4987 \| OPRL1 \| infer 26254 \| OPTC \| infer 403225 \| OR10V7P \| infer 81479 \| OR11I1P \| infer 23538 \| OR52A1 \| infer 58505 \| OSTC \| infer 5021 \| OXTR \| infer 10606 \| PAICS \| infer 9061 \| PAPSS1 \| infer 65217 \| PCDH15 \| infer 27445 \| PCLO \| infer 10846 \| PDE10A \| infer 5142 \| PDE4B \| infer 5144 \| PDE4D \| infer 8654 \| PDE5A \| infer 27115 \| PDE7B \| infer 23590 \| PDSS1 \| infer 79955 \| PDZD7 \| infer 27043 \| PELP1 \| infer 8864 \| PER2 \| infer 267007 \| PGBD3P3 \| infer 5287 \| PIK3C2B \| infer 10531 \| PITRM1 \| infer 5308 \| PITX2 \| infer 5310 \| PKD1 \| infer 81579 \| PLA2G12A \| infer 5332 \| PLCB4 \| infer 51196 \| PLCE1 \| infer 57480 \| PLEKHG1 \| infer 11243 \| PMF1 \| infer 5456 \| POU3F4 \| infer 11281 \| POU6F2 \| infer 27068 \| PPA2 \| infer 5496 \| PPM1G \| infer 151242 \| PPP1R1C \| infer 11107 \| PRDM5 \| infer 5549 \| PRELP \| infer 5578 \| PRKCA \| infer 5592 \| PRKG1 \| infer 5593 \| PRKG2 \| infer 8575 \| PRKRA \| infer 51334 \| PRR16 \| infer 79899 \| PRR5L \| infer 8492 \| PRSS12 \| infer 5787 \| PTPRB \| infer 5789 \| PTPRD \| infer 5791 \| PTPRE \| infer 5793 \| PTPRG \| infer 5797 \| PTPRM \| infer 5799 \| PTPRN2 \| infer 5801 \| PTPRR \| infer 5802 \| PTPRS \| infer 11122 \| PTPRT \| infer 5803 \| PTPRZ1 \| infer 5814 \| PURB \| infer 150962 \| PUS10 \| infer 5860 \| QDPR \| infer 10635 \| RAD51AP1 \| infer 5893 \| RAD52 \| infer 387496 \| RASL11A \| infer 10181 \| RBM5 \| infer 10180 \| RBM6 \| infer 5937 \| RBMS1 \| infer 5068 \| REG3A \| infer 5972 \| REN \| infer 5981 \| RFC1 \| infer 342931 \| RFPL4A \| infer 58480 \| RHOU \| infer 100151664 \| RNU7-66P \| infer 6092 \| ROBO2 \| infer 6096 \| RORB \| infer 6118 \| RPA2 \| infer 6119 \| RPA3 \| infer 100271279 \| RPL13AP15 \| infer 100128347 \| RPL15P15 \| infer 392979 \| RPL18P4 \| infer 100270986 \| RPL31P20 \| infer 6164 \| RPL34 \| infer 343495 \| RPL6P2 \| infer 645387 \| RPL6P27 \| infer 645918 \| RPS13P7 \| infer 390735 \| RPS15AP34 \| infer 100271236 \| RPS21P5 \| infer 100271093 \| RPS23P5 \| infer 645326 \| RPSAP11 \| infer 22800 \| RRAS2 \| infer 10692 \| RRH \| infer 6263 \| RYR3 \| infer 6304 \| SATB1 \| infer 10427 \| SEC24B \| infer 9871 \| SEC24D \| infer 6401 \| SELE \| infer 6402 \| SELL \| infer 26040 \| SETBP1 \| infer 23544 \| SEZ6L \| infer 6445 \| SGCG \| infer 137868 \| SGCZ \| infer 84251 \| SGIP1 \| infer 166929 \| SGMS2 \| infer 53358 \| SHC3 \| infer 6496 \| SIX3 \| infer 8170 \| SLC14A2 \| infer 344371 \| SLC25A5P2 \| infer 144195 \| SLC2A14 \| infer 84255 \| SLC37A3 \| infer 57181 \| SLC39A10 \| infer 6531 \| SLC6A3 \| infer 6533 \| SLC6A6 \| infer 6647 \| SOD1 \| infer 10580 \| SORBS1 \| infer 6660 \| SOX5 \| infer 55133 \| SRBD1 \| infer 6755 \| SSTR5 \| infer 256435 \| ST6GALNAC3 \| infer 53407 \| STX18 \| infer 6834 \| SURF1 \| infer 9145 \| SYNGR1 \| infer 11346 \| SYNPO \| infer 171024 \| SYNPO2 \| infer 6870 \| TACR3 \| infer 6902 \| TBCA \| infer 6905 \| TBCE \| infer 93627 \| TBCK \| infer 6948 \| TCN2 \| infer 146279 \| TEKT5 \| infer 7014 \| TERF2 \| infer 54790 \| TET2 \| infer 7039 \| TGFA \| infer 7042 \| TGFB2 \| infer 7050 \| TGIF1 \| infer 10618 \| TGOLN2 \| infer 7054 \| TH \| infer 92610 \| TIFA \| infer 8914 \| TIMELESS \| infer 83660 \| TLN2 \| infer 114795 \| TMEM132B \| infer 92293 \| TMEM132C \| infer 219854 \| TMEM218 \| infer 5651 \| TMPRSS15 \| infer 7124 \| TNF \| infer 63923 \| TNN \| infer 7155 \| TOP2B \| infer 7166 \| TPH1 \| infer 121278 \| TPH2 \| infer 84231 \| TRAF7 \| infer 133022 \| TRAM1L1 \| infer 28951 \| TRIB2 \| infer 7249 \| TSC2 \| infer 10100 \| TSPAN2 \| infer 54970 \| TTC12 \| infer 7272 \| TTK \| infer 150465 \| TTL \| infer 7323 \| UBE2D3 \| infer 7358 \| UGDH \| infer 7368 \| UGT8 \| infer 8633 \| UNC5C \| infer 54532 \| USP53 \| infer 1462 \| VCAN \| infer 7432 \| VIP \| infer 7434 \| VIPR2 \| infer 402117 \| VWC2L \| infer 7450 \| VWF \| infer 23335 \| WDR7 \| infer 7508 \| XPC \| infer 7520 \| XRCC5 \| infer 7533 \| YWHAH \| infer 60685 \| ZFAND3 \| infer 7678 \| ZNF124 \| infer 284695 \| ZNF326 \| infer 55205 \| ZNF532 \| infer 27332 \| ZNF638 \| infer 22834 \| ZNF652 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:508) 2554 \| GABRA1 \| DISEASES 84245 \| MRI1 \| DISEASES 1815 \| DRD4 \| DISEASES 6343 \| SCT \| DISEASES 9552 \| SPAG7 \| DISEASES 124 \| ADH1A \| DISEASES 9342 \| SNAP29 \| DISEASES 6948 \| TCN2 \| DISEASES 402055 \| SRRD \| DISEASES 80339 \| PNPLA3 \| DISEASES 5173 \| PDYN \| DISEASES 5020 \| OXT \| DISEASES 2742 \| GLRA2 \| DISEASES 84560 \| MT4 \| DISEASES 1428 \| CRYM \| DISEASES 6530 \| SLC6A2 \| DISEASES 1512 \| CTSH \| DISEASES 83988 \| NCALD \| DISEASES 3972 \| LHB \| DISEASES 6449 \| SGTA \| DISEASES 973 \| CD79A \| DISEASES 6142 \| RPL18A \| DISEASES 218 \| ALDH3A1 \| DISEASES 6347 \| CCL2 \| DISEASES 5539 \| PPY \| DISEASES 4790 \| NFKB1 \| DISEASES 2597 \| GAPDH \| DISEASES 55907 \| CMAS \| DISEASES 1839 \| HBEGF \| DISEASES 2908 \| NR3C1 \| DISEASES 5967 \| REG1A \| DISEASES 4985 \| OPRD1 \| DISEASES 51569 \| UFM1 \| DISEASES 847 \| CAT \| DISEASES 2693 \| GHSR \| DISEASES 114784 \| CSMD2 \| DISEASES 4852 \| NPY \| DISEASES 2166 \| FAAH \| DISEASES 55786 \| ZNF415 \| DISEASES 57699 \| CPNE5 \| DISEASES 79143 \| MBOAT7 \| DISEASES 2678 \| GGT1 \| DISEASES 8484 \| GALR3 \| DISEASES 50833 \| TAS2R16 \| DISEASES 7166 \| TPH1 \| DISEASES 57053 \| CHRNA10 \| DISEASES 3630 \| INS \| DISEASES 259232 \| NALCN \| DISEASES 11024 \| LILRA1 \| DISEASES 348 \| APOE \| DISEASES 55821 \| ALLC \| DISEASES 23039 \| XPO7 \| DISEASES 1571 \| CYP2E1 \| DISEASES 55902 \| ACSS2 \| DISEASES 8572 \| PDLIM4 \| DISEASES 84152 \| PPP1R1B \| DISEASES 113 \| ADCY7 \| DISEASES 8864 \| PER2 \| DISEASES 1401 \| CRP \| DISEASES 222 \| ALDH3B2 \| DISEASES 4922 \| NTS \| DISEASES 57578 \| UNC79 \| DISEASES 51124 \| IER3IP1 \| DISEASES 29969 \| MDFIC \| DISEASES 80896 \| NPL \| DISEASES 3357 \| HTR2B \| DISEASES 80704 \| SLC19A3 \| DISEASES 160428 \| ALDH1L2 \| DISEASES 3569 \| IL6 \| DISEASES 2572 \| GAD2 \| DISEASES 9568 \| GABBR2 \| DISEASES 9177 \| HTR3B \| DISEASES 9360 \| PPIG \| DISEASES 27340 \| UTP20 \| DISEASES 3839 \| KPNA3 \| DISEASES 6532 \| SLC6A4 \| DISEASES 217 \| ALDH2 \| DISEASES 1143 \| CHRNB4 \| DISEASES 23469 \| PHF3 \| DISEASES 4025 \| LPO \| DISEASES 4969 \| OGN \| DISEASES 25939 \| SAMHD1 \| DISEASES 2033 \| EP300 \| DISEASES 2906 \| GRIN2D \| DISEASES 3553 \| IL1B \| DISEASES 8273 \| SLC10A3 \| DISEASES 4528 \| MTIF2 \| DISEASES 114879 \| OSBPL5 \| DISEASES 390 \| RND3 \| DISEASES 84708 \| LNX1 \| DISEASES 1001 \| CDH3 \| DISEASES 8540 \| AGPS \| DISEASES 2557 \| GABRA4 \| DISEASES 51191 \| HERC5 \| DISEASES 2892 \| GRIA3 \| DISEASES 64579 \| NDST4 \| DISEASES 2891 \| GRIA2 \| DISEASES 5443 \| POMC \| DISEASES 3781 \| KCNN2 \| DISEASES 11343 \| MGLL \| DISEASES 5924 \| RASGRF2 \| DISEASES 6507 \| SLC1A3 \| DISEASES 56311 \| ANKRD7 \| DISEASES 2568 \| GABRP \| DISEASES 55825 \| PECR \| DISEASES 11112 \| HIBADH \| DISEASES 127 \| ADH4 \| DISEASES 4986 \| OPRK1 \| DISEASES 51083 \| GAL \| DISEASES 55749 \| CCAR1 \| DISEASES 5286 \| PIK3C2A \| DISEASES 56938 \| ARNTL2 \| DISEASES 7112 \| TMPO \| DISEASES 85439 \| STON2 \| DISEASES 5373 \| PMM2 \| DISEASES 23174 \| ZCCHC14 \| DISEASES 10351 \| ABCA8 \| DISEASES 147381 \| CBLN2 \| DISEASES 6531 \| SLC6A3 \| DISEASES 3782 \| KCNN3 \| DISEASES 149111 \| CNIH3 \| DISEASES 5972 \| REN \| DISEASES 80731 \| THSD7B \| DISEASES 130749 \| CPO \| DISEASES 29114 \| TAGLN3 \| DISEASES 2169 \| FABP2 \| DISEASES 8001 \| GLRA3 \| DISEASES 6715 \| SRD5A1 \| DISEASES 635 \| BHMT \| DISEASES 1393 \| CRHBP \| DISEASES 2559 \| GABRA6 \| DISEASES 2561 \| GABRB2 \| DISEASES 2830 \| GPR6 \| DISEASES 92129 \| RIPPLY1 \| DISEASES 3358 \| HTR2C \| DISEASES 6570 \| SLC18A1 \| DISEASES 8973 \| CHRNA6 \| DISEASES 9705 \| ST18 \| DISEASES 1392 \| CRH \| DISEASES 10280 \| SIGMAR1 \| DISEASES 4915 \| NTRK2 \| DISEASES 6506 \| SLC1A2 \| DISEASES 9538 \| EI24 \| DISEASES 10326 \| SIRPB1 \| DISEASES 2904 \| GRIN2B \| DISEASES 3176 \| HNMT \| DISEASES 150 \| ADRA2A \| DISEASES 84076 \| TKTL2 \| DISEASES 23657 \| SLC7A11 \| DISEASES 55768 \| NGLY1 \| DISEASES 5741 \| PTH \| DISEASES 814 \| CAMK4 \| DISEASES 2893 \| GRIA4 \| DISEASES 23171 \| GPD1L \| DISEASES 3087 \| HHEX \| DISEASES 2911 \| GRM1 \| DISEASES 518 \| ATP5G3 \| DISEASES 5651 \| TMPRSS15 \| DISEASES 351 \| APP \| DISEASES 27123 \| DKK2 \| DISEASES 761 \| CA3 \| DISEASES 2890 \| GRIA1 \| DISEASES 114 \| ADCY8 \| DISEASES 6750 \| SST \| DISEASES 6529 \| SLC6A1 \| DISEASES 3361 \| HTR5A \| DISEASES 3763 \| KCNJ6 \| DISEASES 9162 \| DGKI \| DISEASES 1142 \| CHRNB3 \| DISEASES 8659 \| ALDH4A1 \| DISEASES 1636 \| ACE \| DISEASES 7109 \| TRAPPC10 \| DISEASES 2905 \| GRIN2C \| DISEASES 3060 \| HCRT \| DISEASES 1742 \| DLG4 \| DISEASES 115 \| ADCY9 \| DISEASES 114905 \| C1QTNF7 \| DISEASES 2565 \| GABRG1 \| DISEASES 2560 \| GABRB1 \| DISEASES 886 \| CCKAR \| DISEASES 213 \| ALB \| DISEASES 7349 \| UCN \| DISEASES 7123 \| CLEC3B \| DISEASES 128 \| ADH5 \| DISEASES 51151 \| SLC45A2 \| DISEASES 6690 \| SPINK1 \| DISEASES 9607 \| CARTPT \| DISEASES 107 \| ADCY1 \| DISEASES 216 \| ALDH1A1 \| DISEASES 115825 \| WDFY2 \| DISEASES 63876 \| PKNOX2 \| DISEASES 6571 \| SLC18A2 \| DISEASES 2562 \| GABRB3 \| DISEASES 1138 \| CHRNA5 \| DISEASES 2587 \| GALR1 \| DISEASES 113201 \| CASC4 \| DISEASES 1548 \| CYP2A6 \| DISEASES 10653 \| SPINT2 \| DISEASES 956 \| ENTPD3 \| DISEASES 4054 \| LTBP3 \| DISEASES 5368 \| PNOC \| DISEASES 5617 \| PRL \| DISEASES 3479 \| IGF1 \| DISEASES 51181 \| DCXR \| DISEASES 7200 \| TRH \| DISEASES 6869 \| TACR1 \| DISEASES 53343 \| NUDT9 \| DISEASES 1140 \| CHRNB1 \| DISEASES 9455 \| HOMER2 \| DISEASES 1816 \| DRD5 \| DISEASES 2915 \| GRM5 \| DISEASES 2353 \| FOS \| DISEASES 125 \| ADH1B \| DISEASES 255239 \| ANKK1 \| DISEASES 4761 \| NEUROD2 \| DISEASES 8462 \| KLF11 \| DISEASES 113189 \| CHST14 \| DISEASES 152189 \| CMTM8 \| DISEASES 3354 \| HTR1E \| DISEASES 2147 \| F2 \| DISEASES 5644 \| PRSS1 \| DISEASES 9575 \| CLOCK \| DISEASES 3265 \| HRAS \| DISEASES 6868 \| ADAM17 \| DISEASES 836 \| CASP3 \| DISEASES 2944 \| GSTM1 \| DISEASES 374879 \| ZNF699 \| DISEASES 7368 \| UGT8 \| DISEASES 5978 \| REST \| DISEASES 4744 \| NEFH \| DISEASES 160762 \| CCDC63 \| DISEASES 3642 \| INSM1 \| DISEASES 3952 \| LEP \| DISEASES 55584 \| CHRNA9 \| DISEASES 79822 \| ARHGAP28 \| DISEASES 3352 \| HTR1D \| DISEASES 64689 \| GORASP1 \| DISEASES 1191 \| CLU \| DISEASES 57453 \| DSCAML1 \| DISEASES 1136 \| CHRNA3 \| DISEASES 1310 \| COL19A1 \| DISEASES 3350 \| HTR1A \| DISEASES 4684 \| NCAM1 \| DISEASES 57722 \| IGDCC4 \| DISEASES 1129 \| CHRM2 \| DISEASES 285195 \| SLC9A9 \| DISEASES 10938 \| EHD1 \| DISEASES 28232 \| SLCO3A1 \| DISEASES 6863 \| TAC1 \| DISEASES 10611 \| PDLIM5 \| DISEASES 119682 \| OR51L1 \| DISEASES 6330 \| SCN4B \| DISEASES 170572 \| HTR3C \| DISEASES 10194 \| TSHZ1 \| DISEASES 23362 \| PSD3 \| DISEASES 284358 \| MAMSTR \| DISEASES 5179 \| PENK \| DISEASES 1555 \| CYP2B6 \| DISEASES 66000 \| TMEM108 \| DISEASES 57010 \| CABP4 \| DISEASES 400359 \| C15orf53 \| DISEASES 27430 \| MAT2B \| DISEASES 161882 \| ZFPM1 \| DISEASES 4094 \| MAF \| DISEASES 4661 \| MYT1 \| DISEASES 1812 \| DRD1 \| DISEASES 1946 \| EFNA5 \| DISEASES 125061 \| AFMID \| DISEASES 121278 \| TPH2 \| DISEASES 256435 \| ST6GALNAC3 \| DISEASES 5121 \| PCP4 \| DISEASES 8971 \| H1FX \| DISEASES 8811 \| GALR2 \| DISEASES 2894 \| GRID1 \| DISEASES 2520 \| GAST \| DISEASES 796 \| CALCA \| DISEASES 2567 \| GABRG3 \| DISEASES 2903 \| GRIN2A \| DISEASES 4887 \| NPY2R \| DISEASES 113612 \| CYP2U1 \| DISEASES 91582 \| RPS19BP1 \| DISEASES 9001 \| HAP1 \| DISEASES 255061 \| TAC4 \| DISEASES 3840 \| KPNA4 \| DISEASES 9456 \| HOMER1 \| DISEASES 2626 \| GATA4 \| DISEASES 51738 \| GHRL \| DISEASES 342035 \| GLDN \| DISEASES 285242 \| HTR3E \| DISEASES 887 \| CCKBR \| DISEASES 2558 \| GABRA5 \| DISEASES 885 \| CCK \| DISEASES 135 \| ADORA2A \| DISEASES 4987 \| OPRL1 \| DISEASES 79157 \| MFSD11 \| DISEASES 1641 \| DCX \| DISEASES 57142 \| RTN4 \| DISEASES 3363 \| HTR7 \| DISEASES 2289 \| FKBP5 \| DISEASES 23236 \| PLCB1 \| DISEASES 3983 \| ABLIM1 \| DISEASES 6622 \| SNCA \| DISEASES 9369 \| NRXN3 \| DISEASES 64682 \| ANAPC1 \| DISEASES 3266 \| ERAS \| DISEASES 4889 \| NPY5R \| DISEASES 222236 \| NAPEPLD \| DISEASES 4128 \| MAOA \| DISEASES 1395 \| CRHR2 \| DISEASES 113675 \| SDSL \| DISEASES 108 \| ADCY2 \| DISEASES 3146 \| HMGB1 \| DISEASES 5498 \| PPOX \| DISEASES 26053 \| AUTS2 \| DISEASES 220004 \| PPP1R32 \| DISEASES 2918 \| GRM8 \| DISEASES 401024 \| FSIP2 \| DISEASES 4929 \| NR4A2 \| DISEASES 224 \| ALDH3A2 \| DISEASES 54820 \| NDE1 \| DISEASES 10307 \| APBB3 \| DISEASES 65992 \| DDRGK1 \| DISEASES 309 \| ANXA6 \| DISEASES 2534 \| FYN \| DISEASES 223 \| ALDH9A1 \| DISEASES 50618 \| ITSN2 \| DISEASES 7453 \| WARS \| DISEASES 145741 \| C2CD4A \| DISEASES 3359 \| HTR3A \| DISEASES 79710 \| MORC4 \| DISEASES 5265 \| SERPINA1 \| DISEASES 10438 \| C1D \| DISEASES 3240 \| HP \| DISEASES 219844 \| HYLS1 \| DISEASES 2555 \| GABRA2 \| DISEASES 23237 \| ARC \| DISEASES 781 \| CACNA2D1 \| DISEASES 135250 \| RAET1E \| DISEASES 10865 \| ARID5A \| DISEASES 2917 \| GRM7 \| DISEASES 1121 \| CHM \| DISEASES 5992 \| RFX4 \| DISEASES 2571 \| GAD1 \| DISEASES 79694 \| MANEA \| DISEASES 8936 \| WASF1 \| DISEASES 57181 \| SLC39A10 \| DISEASES 387129 \| NPSR1 \| DISEASES 79947 \| DHDDS \| DISEASES 1825 \| DSC3 \| DISEASES 4311 \| MME \| DISEASES 6536 \| SLC6A9 \| DISEASES 55833 \| UBAP2 \| DISEASES 23560 \| GTPBP4 \| DISEASES 8532 \| CPZ \| DISEASES 1312 \| COMT \| DISEASES 460 \| ASTN1 \| DISEASES 4886 \| NPY1R \| DISEASES 115265 \| DDIT4L \| DISEASES 1813 \| DRD2 \| DISEASES 8863 \| PER3 \| DISEASES 116443 \| GRIN3A \| DISEASES 63901 \| FAM111A \| DISEASES 2913 \| GRM3 \| DISEASES 23038 \| WDTC1 \| DISEASES 6000 \| RGS7 \| DISEASES 4139 \| MARK1 \| DISEASES 81788 \| NUAK2 \| DISEASES 127833 \| SYT2 \| DISEASES 3765 \| KCNJ9 \| DISEASES 632 \| BGLAP \| DISEASES 154215 \| NKAIN2 \| DISEASES 1141 \| CHRNB2 \| DISEASES 64077 \| LHPP \| DISEASES 27246 \| RNF115 \| DISEASES 1268 \| CNR1 \| DISEASES 4803 \| NGF \| DISEASES 3351 \| HTR1B \| DISEASES 22854 \| NTNG1 \| DISEASES 1137 \| CHRNA4 \| DISEASES 164045 \| HFM1 \| DISEASES 959 \| CD40LG \| DISEASES 7803 \| PTP4A1 \| DISEASES 58511 \| DNASE2B \| DISEASES 84251 \| SGIP1 \| DISEASES 56889 \| TM9SF3 \| DISEASES 2902 \| GRIN1 \| DISEASES 56654 \| NPDC1 \| DISEASES 2030 \| SLC29A1 \| DISEASES 10420 \| TESK2 \| DISEASES 2899 \| GRIK3 \| DISEASES 83931 \| STK40 \| DISEASES 1025 \| CDK9 \| DISEASES 4674 \| NAP1L2 \| DISEASES 3061 \| HCRTR1 \| DISEASES 347735 \| SERINC2 \| DISEASES 79570 \| NKAIN1 \| DISEASES 4736 \| RPL10A \| DISEASES 23673 \| STX12 \| DISEASES 7099 \| TLR4 \| DISEASES 1269 \| CNR2 \| DISEASES 4524 \| MTHFR \| DISEASES 2550 \| GABBR1 \| DISEASES 1325 \| CORT \| DISEASES 219 \| ALDH1B1 \| DISEASES 4129 \| MAOB \| DISEASES 8514 \| KCNAB2 \| DISEASES 84912 \| SLC35B4 \| DISEASES 6497 \| SKI \| DISEASES 3356 \| HTR2A \| DISEASES 4897 \| NRCAM \| DISEASES 551 \| AVP \| DISEASES 8544 \| PIR \| DISEASES 114131 \| UCN3 \| DISEASES 4676 \| NAP1L4 \| DISEASES 689 \| BTF3 \| DISEASES 8777 \| MPDZ \| DISEASES 7054 \| TH \| DISEASES 2618 \| GART \| DISEASES 2788 \| GNG7 \| DISEASES 1010 \| CDH12 \| DISEASES 200909 \| HTR3D \| DISEASES 4155 \| MBP \| DISEASES 1814 \| DRD3 \| DISEASES 4336 \| MOBP \| DISEASES 2617 \| GARS \| DISEASES 406 \| ARNTL \| DISEASES 79866 \| BORA \| DISEASES 9290 \| GPR55 \| DISEASES 1621 \| DBH \| DISEASES 84628 \| NTNG2 \| DISEASES 51520 \| LARS \| DISEASES 130 \| ADH6 \| DISEASES 2912 \| GRM2 \| DISEASES 174 \| AFP \| DISEASES 137872 \| ADHFE1 \| DISEASES 899 \| CCNF \| DISEASES 594857 \| NPS \| DISEASES 1394 \| CRHR1 \| DISEASES 2687 \| GGT5 \| DISEASES 815 \| CAMK2A \| DISEASES 2897 \| GRIK1 \| DISEASES 24144 \| TFIP11 \| DISEASES 728441 \| GGT2 \| DISEASES 3778 \| KCNMA1 \| DISEASES 7018 \| TF \| DISEASES 2570 \| GABRR2 \| DISEASES 210 \| ALAD \| DISEASES 10618 \| TGOLN2 \| DISEASES 10213 \| PSMD14 \| DISEASES 51194 \| IPO11 \| DISEASES 2641 \| GCG \| DISEASES 1385 \| CREB1 \| DISEASES 285175 \| UNC80 \| DISEASES 375248 \| ANKRD36 \| DISEASES 146713 \| RBFOX3 \| DISEASES 4988 \| OPRM1 \| DISEASES 113235 \| SLC46A1 \| DISEASES 10163 \| WASF2 \| DISEASES 2898 \| GRIK2 \| DISEASES 117579 \| RLN3 \| DISEASES 7124 \| TNF \| DISEASES 8910 \| SGCE \| DISEASES 7086 \| TKT \| DISEASES 79827 \| CLMP \| DISEASES 1408 \| CRY2 \| DISEASES 2566 \| GABRG2 \| DISEASES 57579 \| FAM135A \| DISEASES 23270 \| TSPYL4 \| DISEASES 3586 \| IL10 \| DISEASES 2569 \| GABRR1 \| DISEASES 627 \| BDNF \| DISEASES 54872 \| PIGG \| DISEASES 645073 \| GAGE12G \| DISEASES 4753 \| NELL2 \| DISEASES 3077 \| HFE \| DISEASES 79068 \| FTO \| DISEASES 111 \| ADCY5 \| DISEASES 131 \| ADH7 \| DISEASES 79772 \| MCTP1 \| DISEASES 346007 \| EYS \| DISEASES 285605 \| DTWD2 \| DISEASES 55819 \| RNF130 \| DISEASES 3066 \| HDAC2 \| DISEASES 9312 \| KCNB2 \| DISEASES 54622 \| ARL15 \| DISEASES 54970 \| TTC12 \| DISEASES 9152 \| SLC6A5 \| DISEASES 10846 \| PDE10A \| DISEASES 27164 \| SALL3 \| DISEASES 51550 \| CINP \| DISEASES 51802 \| ASIC5 \| DISEASES 9 \| NAT1 \| DISEASES 6999 \| TDO2 \| DISEASES 136541 \| PRSS58 \| DISEASES 8972 \| MGAM \| DISEASES 5726 \| TAS2R38 \| DISEASES 79611 \| ACSS3 \| DISEASES 283450 \| HECTD4 \| DISEASES 4329 \| ALDH6A1 \| DISEASES 9628 \| RGS6 \| DISEASES 4293 \| MAP3K9 \| DISEASES 8742 \| TNFSF12 \| DISEASES 2108 \| ETFA \| DISEASES 124975 \| GGT6 \| DISEASES 64772 \| ENGASE \| DISEASES 391104 \| VHLL \| DISEASES 339894 \| LINC00880 \| DISEASES 677833 \| SNORA54 \| DISEASES
Locus	(Waiting for update.)

Disease ID	508
Disease	alcohol dependence
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:1) HP:0000707 \| Neurological abnormality
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:27) HP:0000739 \| Anxiety \| 10 HP:0000716 \| Depression \| 9 HP:0100543 \| Cognitive deficits \| 6 HP:0000708 \| Behavioral problems \| 5 HP:0001513 \| Obesity \| 2 HP:0100710 \| Impulsivity \| 2 HP:0007302 \| Bipolar disorder \| 2 HP:0002059 \| Degeneration of cerebrum \| 2 HP:0100785 \| Insomnia \| 2 HP:0000802 \| Erectile dysfunction \| 2 HP:0001578 \| Hypercortisolism \| 1 HP:0100033 \| Tic disorder \| 1 HP:0000989 \| pruritis \| 1 HP:0010885 \| Aseptic necrosis \| 1 HP:0001250 \| Seizures \| 1 HP:0012075 \| Personality disorder \| 1 HP:0000738 \| Sensory hallucination \| 1 HP:0002120 \| Cerebral cortical atrophy \| 1 HP:0000855 \| Insulin resistance \| 1 HP:0002529 \| Neuronal loss in central nervous system \| 1 HP:0100753 \| Schizophrenia \| 1 HP:0100754 \| Mania \| 1 HP:0001297 \| Cerebral vascular events \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0000718 \| Aggressive behaviour \| 1 HP:0001645 \| Sudden cardiac death \| 1 HP:0001394 \| Hepatic cirrhosis \| 1

Disease ID	508
Disease	alcohol dependence
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:251)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1000579	22004471	53407	STX18	umls:C0001973	GAD	[Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.]	0.002367032	2012	NA	4	4717767	A	G
rs10090288	22064162	286097	MICU3	umls:C0001973	GAD	[These results underscore the complex genomic influences on psychiatric phenotypes and suggest that a comorbid phenotype is partially influenced by genetic variants that do not affect AD alone.]	0.002367032	2012	MICU3	8	17072126	A	C
rs10160548	23757001	6532	SLC6A4	umls:C0001973	BeFree	Subsequent analysis of these two interaction models revealed an OR of 2.71 and 2.80, respectively, for AD (P < 0.001) in carriers of genotype combinations 5'-HTTLPR:LL/LS(SLC6A4)-rs1042173:TT/TG(SLC6A4)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B) and 5'-HTTLPR:LL/LS(SLC6A4)-rs10160548:GT/TT(HTR3A)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B).	0.215482118	2013	HTR3A	11	113985959	G	T
rs10160548	23757001	3359	HTR3A	umls:C0001973	BeFree	Subsequent analysis of these two interaction models revealed an OR of 2.71 and 2.80, respectively, for AD (P < 0.001) in carriers of genotype combinations 5'-HTTLPR:LL/LS(SLC6A4)-rs1042173:TT/TG(SLC6A4)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B) and 5'-HTTLPR:LL/LS(SLC6A4)-rs10160548:GT/TT(HTR3A)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B).	0.003181358	2013	HTR3A	11	113985959	G	T
rs10224675	20202923	27010	TPK1	umls:C0001973	GAD	[A genome-wide association study of alcohol dependence.]	0.002367032	2010	TPK1	7	144595669	A	G
rs1039002	22205951	10846	PDE10A	umls:C0001973	BeFree	Bipolar disorder with psychosis and/or substance abuse in the absence of alcohol dependence was associated with the rare variant rs1039002 in the vicinity of the gene phosphodiesterase 10A (PDE10A) on chromosome 6q27 (p = 1.7×10⁻⁸).	0.002638474	2011	NA	6	165741969	G	A
rs1042173	23757001	3359	HTR3A	umls:C0001973	BeFree	Subsequent analysis of these two interaction models revealed an OR of 2.71 and 2.80, respectively, for AD (P < 0.001) in carriers of genotype combinations 5'-HTTLPR:LL/LS(SLC6A4)-rs1042173:TT/TG(SLC6A4)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B) and 5'-HTTLPR:LL/LS(SLC6A4)-rs10160548:GT/TT(HTR3A)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B).	0.003181358	2013	SLC6A4	17	30197993	A	C
rs1042173	23757001	6532	SLC6A4	umls:C0001973	BeFree	Subsequent analysis of these two interaction models revealed an OR of 2.71 and 2.80, respectively, for AD (P < 0.001) in carriers of genotype combinations 5'-HTTLPR:LL/LS(SLC6A4)-rs1042173:TT/TG(SLC6A4)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B) and 5'-HTTLPR:LL/LS(SLC6A4)-rs10160548:GT/TT(HTR3A)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B).	0.215482118	2013	SLC6A4	17	30197993	A	C
rs1076560	17196743	1813	DRD2	umls:C0001973	BeFree	In this study, we examined the association between the single-nucleotide polymorphism (SNP) rs1076560 of the dopamine receptor D2 (DRD2) gene and susceptibility to alcoholism.	0.203722004	2007	DRD2	11	113412966	C	A
rs10892169	21445666	57453	DSCAML1	umls:C0001973	BeFree	Interestingly, four SNPs in DSCAML1 at 11q23 reached the genome-wide significance (the top SNP is rs10892169 with P = 5.31 × 10(-9)), while rs637547 in NKAIN2 at 6q21 showed strong association with AD (P = 5.11 × 10(-7)) in the replication sample.	0.002638474	2011	DSCAML1	11	117762339	A	G
rs10892169	21445666	154215	NKAIN2	umls:C0001973	BeFree	Interestingly, four SNPs in DSCAML1 at 11q23 reached the genome-wide significance (the top SNP is rs10892169 with P = 5.31 × 10(-9)), while rs637547 in NKAIN2 at 6q21 showed strong association with AD (P = 5.11 × 10(-7)) in the replication sample.	0.000271442	2011	DSCAML1	11	117762339	A	G
rs10893365	20202923	63876	PKNOX2	umls:C0001973	GAD	[A genome-wide association study of alcohol dependence.]	0.130011012	2010	PKNOX2	11	125306541	T	C
rs10893366	20202923	63876	PKNOX2	umls:C0001973	GAD	[A genome-wide association study of alcohol dependence.]	0.130011012	2010	PKNOX2	11	125308507	C	T
rs10893366	21956439	63876	PKNOX2	umls:C0001973	GAD	[Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.]	0.130011012	2012	PKNOX2	11	125308507	C	T
rs10908907	21529783	10912	GADD45G	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	NA	9	89634669	G	A
rs110402	24623788	1394	CRHR1	umls:C0001973	BeFree	This study examined the influence of an intronic CRHR1 gene variant, rs110402, on brain responses to negative emotional words, negative emotional traits, and alcohol use in adolescents and young adults at high risk for alcoholism.	0.005081451	2014	CRHR1;MGC57346-CRHR1	17	45802681	G	A
rs1109501	21529783	4589	MUC7	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	MUC7	4	70463773	G	A
rs11205760	NA	11124	FAF1	umls:C0001973	GAD	NA	0.004734064	NA	FAF1	1	50708658	C	T
rs11558538	15770103	3176	HNMT	umls:C0001973	BeFree	Thr105Ile, a functional polymorphism of histamine N-methyltransferase, is associated with alcoholism in two independent populations.	0.00554839	2005	HNMT	2	138002079	C	T
rs11558538	16950574	3176	HNMT	umls:C0001973	BeFree	Association of THR105Ile, a functional polymorphism of histamine N-methyltransferase (HNMT), with alcoholism in German Caucasians.	0.00554839	2007	HNMT	2	138002079	C	T
rs11558538	21138759	3176	HNMT	umls:C0001973	BeFree	The Thr105Ile polymorphism was associated with Parkinson's disease, essential tremor, attention-deficit hyperactivity disorder (ADHD), asthma and alcoholism, thus we tested possible association of HNMT functional polymorphism with AD.	0.00554839	2011	HNMT	2	138002079	C	T
rs1176744	20838391	9177	HTR3B	umls:C0001973	BeFree	The HTR3B rs1176744 gain-of-function Ser129 allele predicted alcohol dependence (P=0.002) and low 5-HTTLPR activity predicted cocaine/heroin dependence (P=0.01).	0.003181358	2011	HTR3B	11	113932306	A	C
rs1176744	23757001	6532	SLC6A4	umls:C0001973	BeFree	Subsequent analysis of these two interaction models revealed an OR of 2.71 and 2.80, respectively, for AD (P < 0.001) in carriers of genotype combinations 5'-HTTLPR:LL/LS(SLC6A4)-rs1042173:TT/TG(SLC6A4)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B) and 5'-HTTLPR:LL/LS(SLC6A4)-rs10160548:GT/TT(HTR3A)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B).	0.215482118	2013	HTR3B	11	113932306	A	C
rs1176744	23757001	3359	HTR3A	umls:C0001973	BeFree	Subsequent analysis of these two interaction models revealed an OR of 2.71 and 2.80, respectively, for AD (P < 0.001) in carriers of genotype combinations 5'-HTTLPR:LL/LS(SLC6A4)-rs1042173:TT/TG(SLC6A4)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B) and 5'-HTTLPR:LL/LS(SLC6A4)-rs10160548:GT/TT(HTR3A)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B).	0.003181358	2013	HTR3B	11	113932306	A	C
rs1176744	20838391	6532	SLC6A4	umls:C0001973	BeFree	The HTR3B rs1176744 gain-of-function Ser129 allele predicted alcohol dependence (P=0.002) and low 5-HTTLPR activity predicted cocaine/heroin dependence (P=0.01).	0.215482118	2011	HTR3B	11	113932306	A	C
rs1229984	23969552	125	ADH1B	umls:C0001973	BeFree	Genetic polymorphisms of alcohol dehydrogenase-1B (ADH1B, rs1229984) and aldehyde dehydrogenase-2 (ALDH2, rs671) affect ethanol (EtOH) metabolism and susceptibility to alcoholism.	0.347415629	2014	ADH1B	4	99318162	T	C
rs1229984	23969552	217	ALDH2	umls:C0001973	BeFree	Genetic polymorphisms of alcohol dehydrogenase-1B (ADH1B, rs1229984) and aldehyde dehydrogenase-2 (ALDH2, rs671) affect ethanol (EtOH) metabolism and susceptibility to alcoholism.	0.470944373	2014	ADH1B	4	99318162	T	C
rs1229984	25410943	125	ADH1B	umls:C0001973	BeFree	We tested the most significant ADH1B single nucleotide polymorphisms for alcohol dependence from a genomewide association study with this sample, ADH1B-rs1229984 (Arg48His) and ADH1B-rs2066702 (Arg370Cys), in EA and AA subsamples, respectively.	0.347415629	2014	ADH1B	4	99318162	T	C
rs1229984	20180859	10327	AKR1A1	umls:C0001973	BeFree	Because alcohol dehydrogenase (ADH1B) His47Arg and mitochondrial aldehyde dehydrogenase (ALDH2) Glu487Lys single nucleotide polymorphisms (SNPs), which affect alcohol metabolism, have been reported to exert significant impacts on alcohol consumption and on the risk for alcoholism in East Asia populations, we explored associations of the two functional SNPs with suicide using a case-control study of 283 completed suicides and 319 control subjects in the Japanese population.	0.015200745	2010	ADH1B	4	99318162	T	C
rs1229984	23456092	125	ADH1B	umls:C0001973	GWASCAT	In case-control analysis, ADH1B rs1229984 (H47R) showed the most significant association with the risk of AD (p = 2.63 × 10(-21), OR = 2.35).	0.347415629	2013	ADH1B	4	99318162	T	C
rs1229984	15048643	10327	AKR1A1	umls:C0001973	BeFree	In recent studies of the role of the alcohol dehydrogenase genes (ADH) in alcoholism the ADH1B Arg47His polymorphism appears to affect risk via a protective effect associated with the ADH1B*47His.	0.015200745	2004	ADH1B	4	99318162	T	C
rs1229984	23456092	125	ADH1B	umls:C0001973	BeFree	In case-control analysis, ADH1B rs1229984 (H47R) showed the most significant association with the risk of AD (p = 2.63 × 10(-21), OR = 2.35).	0.347415629	2013	ADH1B	4	99318162	T	C
rs1229984	24735490	551	AVP	umls:C0001973	BeFree	In conclusion, the rare ADH1B rs1229984 mutation provides significant protection against ADS in this British and Irish population; other variants in the ADH gene cluster also alter ADS risk, although the strong linkage disequilibrium between SNPs at this location precluded clear identification of the variant(s) driving the associations.	0.014386419	2016	ADH1B	4	99318162	T	C
rs1229984	15048643	125	ADH1B	umls:C0001973	BeFree	In recent studies of the role of the alcohol dehydrogenase genes (ADH) in alcoholism the ADH1B Arg47His polymorphism appears to affect risk via a protective effect associated with the ADH1B*47His.	0.347415629	2004	ADH1B	4	99318162	T	C
rs12388359	19581569	1183	CLCN4	umls:C0001973	GAD	[This is the first GWAS and follow-up study to identify a genome-wide significant association in alcohol dependence. Further independent studies are required to confirm these findings.]	0.002367032	2009	NA	X	10263651	G	T
rs12529	21323680	8644	AKR1C3	umls:C0001973	BeFree	The minor allele for both SNPs was more common among controls than subjects with AD: SRD5A1 rs248793 C-allele (χ(2)(1) = 7.6, p = 0.006) and AKR1C3 rs12529 G-allele (χ(2)(1) = 14.6, p = 0.0001).	0.002909916	2011	AKR1C3	10	5094459	C	G
rs130058	19519719	3351	HTR1B	umls:C0001973	BeFree	The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence.	0.020912294	2009	HTR1B;LOC105377864	6	77463564	T	A
rs13150562	19581569	51752	ERAP1	umls:C0001973	GAD	[Genome-wide association study of alcohol dependence.]	0.002367032	2009	NDST4	4	115036437	T	C
rs13150562	19581569	831	CAST	umls:C0001973	GAD	[Genome-wide association study of alcohol dependence.]	0.002367032	2009	NDST4	4	115036437	T	C
rs1318937	20202923	9467	SH3BP5	umls:C0001973	GAD	[A genome-wide association study of alcohol dependence.]	0.002367032	2010	SH3BP5;SH3BP5-AS1	3	15253857	A	G
rs1318937	22488850	23473	CAPN7	umls:C0001973	GAD	[Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.]	0.004734064	2012	SH3BP5;SH3BP5-AS1	3	15253857	A	G
rs1318937	21956439	23473	CAPN7	umls:C0001973	GAD	[Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.]	0.004734064	2012	SH3BP5;SH3BP5-AS1	3	15253857	A	G
rs13297480	19175764	8777	MPDZ	umls:C0001973	GAD	[Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry.]	0.003181358	2009	MPDZ	9	13219571	T	C
rs13423141	NA	1496	CTNNA2	umls:C0001973	GAD	NA	0.002638474	NA	CTNNA2	2	80543683	C	T
rs1344694	22004471	55686	MREG	umls:C0001973	GAD	[Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.]	0.005005506	2012	NA	2	216028914	T	G
rs1380131	21529783	80821	DDHD1	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	LOC105370504	14	53606140	C	T
rs1426153	22488850	63876	PKNOX2	umls:C0001973	GAD	[Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.]	0.130011012	2012	PKNOX2	11	125300743	A	G
rs1570989	22488850	3096	HIVEP1	umls:C0001973	GAD	[Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.]	0.002367032	2012	HIVEP1	6	12048594	A	G
rs16139	20554694	4852	NPY	umls:C0001973	GAD	[The role of DRD2 and NPY on alcohol dependence was also supported.]	0.219088146	2010	NPY	7	24285260	T	C,A
rs16969968	23334941	1138	CHRNA5	umls:C0001973	BeFree	The analysis revealed a candidate SNP from CHRNA5, rs16969968, associated with both ND and AD, and replicated the findings in an independent dataset with a P-value of 1.06 × 10(-03) .	0.132649486	2013	CHRNA5	15	78590583	G	A
rs1701137	19204064	6869	TACR1	umls:C0001973	BeFree	Four single-nucleotide polymorphisms (rs3771829, rs3771833, rs3771856, and rs1701137) at the TACR1 gene, previously known to be associated with bipolar disorder or alcoholism, were strongly associated with ADHD.	0.123724241	2010	VPS53;LOC105371476	17	572682	C	T
rs17427389	22488850	57480	PLEKHG1	umls:C0001973	GAD	[Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.]	0.002367032	2012	PLEKHG1	6	150841979	G	A
rs17750015	22064162	23335	WDR7	umls:C0001973	GAD	[These results underscore the complex genomic influences on psychiatric phenotypes and suggest that a comorbid phenotype is partially influenced by genetic variants that do not affect AD alone.]	0.002367032	2012	WDR7	18	56730391	T	C
rs1799971	23032071	4988	OPRM1	umls:C0001973	BeFree	Variation at a single nucleotide polymorphism in the μ-opioid receptor gene (OPRM1), A118G (Asn40Asp), may moderate naltrexone (NTX) effects in alcohol dependence.	0.159066562	2013	OPRM1	6	154039662	A	G
rs1799971	22909206	4988	OPRM1	umls:C0001973	BeFree	Influence of the OPRM1 A118G polymorphism on alcohol-induced euphoria, risk for alcoholism and the clinical efficacy of naltrexone.	0.159066562	2012	OPRM1	6	154039662	A	G
rs1799971	20077761	4988	OPRM1	umls:C0001973	BeFree	These results suggest that, while the risk of alcoholism in Korean men is predominantly affected by the presence of the ALDH2 1/1 genotype, the risk of alcoholism in Korean women is primarily associated with the ADH2 1/1 genotype and G carrier genotype of the OPRM1 A118G polymorphism.	0.159066562	2009	OPRM1	6	154039662	A	G
rs1799971	15584875	125	ADH1B	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.347415629	2004	OPRM1	6	154039662	A	G
rs1799971	15584875	4988	OPRM1	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.159066562	2004	OPRM1	6	154039662	A	G
rs1799971	23254216	4988	OPRM1	umls:C0001973	BeFree	The A118G (rs 1799971) polymorphism in the mu-opioid receptor gene (OPRM1) has been reported to be associated with alcohol addiction.	0.159066562	2013	OPRM1	6	154039662	A	G
rs1799971	15584875	1312	COMT	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.157100455	2004	OPRM1	6	154039662	A	G
rs1799971	21946895	4988	OPRM1	umls:C0001973	BeFree	OPRM1 A118G genotype fails to predict the effectiveness of naltrexone treatment for alcohol dependence.	0.159066562	2011	OPRM1	6	154039662	A	G
rs1799971	24220019	4988	OPRM1	umls:C0001973	BeFree	Genetic analyses of the level of response to alcohol, particularly of the functional OPRM1 A118G polymorphism and 5' and 3' functional polymorphisms in SLC6A4, are beginning to provide insights into the etiology of alcoholism and also genotype-stratified subgroup responses to naltrexone and SSRIs/ondansetron respectively.	0.159066562	2013	OPRM1	6	154039662	A	G
rs1799971	20077761	217	ALDH2	umls:C0001973	BeFree	These results suggest that, while the risk of alcoholism in Korean men is predominantly affected by the presence of the ALDH2 1/1 genotype, the risk of alcoholism in Korean women is primarily associated with the ADH2 1/1 genotype and G carrier genotype of the OPRM1 A118G polymorphism.	0.470944373	2009	OPRM1	6	154039662	A	G
rs1799971	22551036	4988	OPRM1	umls:C0001973	BeFree	Two hundred and sixty-five nontreatment-seeking individuals with alcohol dependence were genotyped a priori for the OPRM1 asn40asp SNP and post hoc for DAT (SLC6A3) 9 and 10 VNTRs.	0.159066562	2012	OPRM1	6	154039662	A	G
rs1799971	23543091	4988	OPRM1	umls:C0001973	BeFree	A single-nucleotide polymorphism (SNP) within the OPRM1 gene, A118G, leading to an amino acid change (Asn40Asp) in the extracellular portion of the receptor, has been implicated in alcoholism as well as in drug addiction, pain sensitivity and stress response, and in animal and human studies relates to the alcohol-dependent phenotype as well as to the treatment response to the µ-opioid antagonist naltrexone.	0.159066562	2014	OPRM1	6	154039662	A	G
rs1799971	21895723	4988	OPRM1	umls:C0001973	BeFree	The role of the Asn40Asp polymorphism of the mu opioid receptor gene (OPRM1) on alcoholism etiology and treatment: a critical review.	0.159066562	2012	OPRM1	6	154039662	A	G
rs1799971	22397905	4988	OPRM1	umls:C0001973	BeFree	The Asn40Asp variant (A118G) of the μ opioid receptor (OPRM1) gene is thought to contribute to the development and treatment of alcohol dependence.	0.159066562	2013	OPRM1	6	154039662	A	G
rs1799971	15252283	4988	OPRM1	umls:C0001973	BeFree	The functional polymorphism (A118G) of the mu-opioid receptor gene (OPRM1) is thought to have clinical significance in the treatment of alcohol dependence.	0.159066562	2004	OPRM1	6	154039662	A	G
rs1799971	16679777	4988	OPRM1	umls:C0001973	BeFree	Association of mu-opioid receptor gene polymorphism A118G with alcohol dependence in a Japanese population.	0.159066562	2006	OPRM1	6	154039662	A	G
rs1799971	22071118	4988	OPRM1	umls:C0001973	BeFree	Ethnic-specific meta-analyses of association between the OPRM1 A118G polymorphism and alcohol dependence among Asians and Caucasians.	0.159066562	2012	OPRM1	6	154039662	A	G
rs1799971	20077761	125	ADH1B	umls:C0001973	BeFree	These results suggest that, while the risk of alcoholism in Korean men is predominantly affected by the presence of the ALDH2 1/1 genotype, the risk of alcoholism in Korean women is primarily associated with the ADH2 1/1 genotype and G carrier genotype of the OPRM1 A118G polymorphism.	0.347415629	2009	OPRM1	6	154039662	A	G
rs1799971	19764934	4988	OPRM1	umls:C0001973	BeFree	Our results suggest main effect of education background, OPRM1 A118G, and DRD2 -141C Ins/Del as well as education*OPRM1 interaction in contribution to moderate and/or severe alcoholism in Mexican Americans.	0.159066562	2009	OPRM1	6	154039662	A	G
rs1799971	11424981	4988	OPRM1	umls:C0001973	BeFree	In the present investigation we hypothesized the A118G (Asn40Asp) polymorphism of the mu-opioid receptor gene (OPRM1) as a particular vulnerability factor for heroin and alcohol dependence.	0.159066562	2001	OPRM1	6	154039662	A	G
rs1799971	21900886	4988	OPRM1	umls:C0001973	BeFree	Recent clinical and laboratory studies have shown that the effects of naltrexone for alcoholism may be moderated by the Asn40Asp single-nucleotide polymorphism (SNP) of the μ-opioid receptor gene (OPRM1).	0.159066562	2012	OPRM1	6	154039662	A	G
rs1799971	19764934	1813	DRD2	umls:C0001973	BeFree	Our results suggest main effect of education background, OPRM1 A118G, and DRD2 -141C Ins/Del as well as education*OPRM1 interaction in contribution to moderate and/or severe alcoholism in Mexican Americans.	0.203722004	2009	OPRM1	6	154039662	A	G
rs1799971	22587755	4988	OPRM1	umls:C0001973	BeFree	The best-studied functional genetic variant relevant to alcoholism treatment is rs1799971, a single-nucleotide polymorphism in exon 1 of the OPRM1 gene that encodes the μ-opioid receptor.	0.159066562	2012	OPRM1	6	154039662	A	G
rs1799971	24220019	6532	SLC6A4	umls:C0001973	BeFree	Genetic analyses of the level of response to alcohol, particularly of the functional OPRM1 A118G polymorphism and 5' and 3' functional polymorphisms in SLC6A4, are beginning to provide insights into the etiology of alcoholism and also genotype-stratified subgroup responses to naltrexone and SSRIs/ondansetron respectively.	0.215482118	2013	OPRM1	6	154039662	A	G
rs1799971	17374034	4988	OPRM1	umls:C0001973	BeFree	These results do not support association of the OPRM1 Asn40Asp polymorphism with NTX treatment response for AD.	0.159066562	2007	OPRM1	6	154039662	A	G
rs1799971	22551036	6531	SLC6A3	umls:C0001973	BeFree	Two hundred and sixty-five nontreatment-seeking individuals with alcohol dependence were genotyped a priori for the OPRM1 asn40asp SNP and post hoc for DAT (SLC6A3) 9 and 10 VNTRs.	0.035190431	2012	OPRM1	6	154039662	A	G
rs1799971	23729673	4988	OPRM1	umls:C0001973	BeFree	μ-Opioid receptor gene (OPRM1) polymorphism A118G: lack of association in Finnish populations with alcohol dependence or alcohol consumption.	0.159066562	2014	OPRM1	6	154039662	A	G
rs1800497	20554694	1813	DRD2	umls:C0001973	GAD	[The role of DRD2 and NPY on alcohol dependence was also supported.]	0.203722004	2010	ANKK1	11	113400106	G	A
rs1801028	9259374	1813	DRD2	umls:C0001973	BeFree	Linkage and association of a functional DRD2 variant [Ser311Cys] and DRD2 markers to alcoholism, substance abuse and schizophrenia in Southwestern American Indians.	0.203722004	1997	DRD2	11	113412762	G	C
rs1801028	9650635	1813	DRD2	umls:C0001973	BeFree	A functionally deficient DRD2 variant [Ser311Cys] is not linked to alcoholism and substance abuse.	0.203722004	1998	DRD2	11	113412762	G	C
rs1806191	15812607	2904	GRIN2B	umls:C0001973	BeFree	Moreover, we hypothesized that another genetic variation within GRIN2B (rs1806191) may have an effect in the etiology of alcoholism or withdrawal-related traits.	0.021279544	2005	GRIN2B	12	13563704	G	A,T
rs1864982	19581569	5521	PPP2R2B	umls:C0001973	GAD	[This is the first GWAS and follow-up study to identify a genome-wide significant association in alcohol dependence. Further independent studies are required to confirm these findings.]	0.002367032	2009	PPP2R2B	5	146941260	G	T
rs1932011	NA	4153	MBL2	umls:C0001973	GAD	NA	0.002638474	NA	NA	10	53597376	A	C
rs195204	21529783	10100	TSPAN2	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	NA	1	115191470	T	C
rs1986644	21445666	1910	EDNRB	umls:C0001973	BeFree	The most significant association with AD was observed with SNP rs1986644 (P = 8.51 × 10(-6)) at 13q22 near EDNRB gene.	0.000271442	2011	RNF219-AS1	13	78409942	G	C
rs2039617	20202923	387707	CC2D2B	umls:C0001973	GAD	[A genome-wide association study of alcohol dependence.]	0.002367032	2010	CC2D2B;ENTPD1-AS1	10	95999446	G	A
rs2066702	25410943	125	ADH1B	umls:C0001973	BeFree	We tested the most significant ADH1B single nucleotide polymorphisms for alcohol dependence from a genomewide association study with this sample, ADH1B-rs1229984 (Arg48His) and ADH1B-rs2066702 (Arg370Cys), in EA and AA subsamples, respectively.	0.347415629	2014	ADH1B	4	99307860	G	A
rs2072450	23693003	2903	GRIN2A	umls:C0001973	BeFree	In the present study we report reduced amygdala activity during the acquisition of conditioned fear in healthy carriers of a risk variant for alcoholism (rs2072450) in the NR2A subunit-containing N-methyl-d-aspartate (NMDA)-receptor.	0.003181358	2013	GRIN2A	16	9821855	C	A
rs2140418	21529783	23294	ANKS1A	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	ANKS1A	6	35007638	T	C
rs2173201	24889829	125	ADH1B	umls:C0001973	BeFree	Three mQTLs (rs2173201, rs4147542, and rs4147541 in ADH1B-AHD1C gene cluster region) found in AAs were previously identified by our genome-wide association studies as being significantly associated with AD in AAs.	0.347415629	2014	NA	4	99329813	C	A
rs2218433	NA	4685	NCAM2	umls:C0001973	GAD	NA	0.004734064	NA	NCAM2	21	21305454	A	G
rs2369955	21529783	348808	NPHP3-AS1	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	NA	3	132974744	A	C
rs237238	21529783	3092	HIP1	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	HIP1	7	75582098	A	G
rs237899	22064162	5021	OXTR	umls:C0001973	GAD	[These results underscore the complex genomic influences on psychiatric phenotypes and suggest that a comorbid phenotype is partially influenced by genetic variants that do not affect AD alone.]	0.002367032	2012	OXTR	3	8766829	G	A
rs248793	24838369	3291	HSD11B2	umls:C0001973	BeFree	We previously reported that a common nonsynonymous polymorphism, AKR1C3 2 in the gene encoding the enzyme 3α-HSD2/17β-HSD5, and a synonymous single nucleotide polymorphism (SNP), rs248793, in SRD5A1, which encodes 5α-reductase, were associated with alcohol dependence (AD).	0.000271442	2014	SRD5A1;NSUN2	5	6633666	C	G
rs248793	24838369	6715	SRD5A1	umls:C0001973	BeFree	We previously reported that a common nonsynonymous polymorphism, AKR1C3 2 in the gene encoding the enzyme 3α-HSD2/17β-HSD5, and a synonymous single nucleotide polymorphism (SNP), rs248793, in SRD5A1, which encodes 5α-reductase, were associated with alcohol dependence (AD).	0.000542884	2014	SRD5A1;NSUN2	5	6633666	C	G
rs248793	24838369	6060	RNU1-4	umls:C0001973	BeFree	We previously reported that a common nonsynonymous polymorphism, AKR1C3 2 in the gene encoding the enzyme 3α-HSD2/17β-HSD5, and a synonymous single nucleotide polymorphism (SNP), rs248793, in SRD5A1, which encodes 5α-reductase, were associated with alcohol dependence (AD).	0.000271442	2014	SRD5A1;NSUN2	5	6633666	C	G
rs248793	21323680	8644	AKR1C3	umls:C0001973	BeFree	The minor allele for both SNPs was more common among controls than subjects with AD: SRD5A1 rs248793 C-allele (χ(2)(1) = 7.6, p = 0.006) and AKR1C3 rs12529 G-allele (χ(2)(1) = 14.6, p = 0.0001).	0.002909916	2011	SRD5A1;NSUN2	5	6633666	C	G
rs2548145	21529783	1601	DAB2	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	NA	5	40134675	G	A
rs25531	25770138	6532	SLC6A4	umls:C0001973	BeFree	Alcohol dependence and serotonin transporter functional polymorphisms 5-HTTLPR and rs25531 in an Italian population.	0.215482118	2015	SLC6A4;LOC105371720	17	30237328	T	C
rs2727943	22205951	152330	CNTN4	umls:C0001973	BeFree	Bipolar disorder with alcohol dependence and other co-morbidities was associated with SNP rs2727943 (p = 3.3×10⁻⁸) on chromosome 3p26.3 located between the genes contactin-4 precursor (BIG-2) and contactin 6 (CNTN6).	0.002638474	2011	NA	3	1856289	T	C
rs2727943	22205951	27255	CNTN6	umls:C0001973	BeFree	Bipolar disorder with alcohol dependence and other co-morbidities was associated with SNP rs2727943 (p = 3.3×10⁻⁸) on chromosome 3p26.3 located between the genes contactin-4 precursor (BIG-2) and contactin 6 (CNTN6).	0.000271442	2011	NA	3	1856289	T	C
rs2727943	22205951	10564	ARFGEF2	umls:C0001973	BeFree	Bipolar disorder with alcohol dependence and other co-morbidities was associated with SNP rs2727943 (p = 3.3×10⁻⁸) on chromosome 3p26.3 located between the genes contactin-4 precursor (BIG-2) and contactin 6 (CNTN6).	0.000271442	2011	NA	3	1856289	T	C
rs279858	24557088	2555	GABRA2	umls:C0001973	BeFree	We used linear mixed models to examine the effects of dutasteride and alcohol on BAES and SS responses and the interaction of dutasteride with the GABRA2 alcohol dependence-associated polymorphism rs279858.	0.171173163	2014	GABRA2	4	46312576	T	C
rs279858	24166645	2555	GABRA2	umls:C0001973	BeFree	We genotyped subjects for three SNPs previously associated with AD: rs279858 in GABRA2, and rs7654165 and rs6447493 in GABRG1.	0.171173163	2014	GABRA2	4	46312576	T	C
rs279871	20698837	2555	GABRA2	umls:C0001973	BeFree	In this study, we stratified subjects who had participated in an fMRI study of alcohol cue responses according to their genotype at a SNP in GABRA2 (rs279871) shown to be associated with alcohol dependence (Edenberg et al., 2004).	0.171173163	2010	GABRA2	4	46303716	T	C
rs279871	19783384	2555	GABRA2	umls:C0001973	BeFree	Consistent with previous findings, the results do not support the association between GABRA2 SNP rs279871 and AD in adolescents.	0.171173163	2010	GABRA2	4	46303716	T	C
rs2810114	22004471	22990	PCNX	umls:C0001973	GAD	[Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.]	0.002638474	2012	PCNX	14	70928887	C	A
rs2827312	21529783	4685	NCAM2	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.004734064	2011	NA	21	22259356	G	T
rs3027172	21828288	5187	PER1	umls:C0001973	BeFree	In a confirmatory analysis, association of hPer1 rs3027172 with alcohol dependence was shown.	0.000542884	2011	PER1	17	8152405	A	G
rs34315573	15542698	6531	SLC6A3	umls:C0001973	BeFree	PCR-based assays showed that alcoholism was associated with polymorphisms of the dopamine D2 receptor (DRD2) TaqI B (P = .029) and the GABAA-beta2 subunit C1412T (P = .012) genes, but not with the glutamate receptor subunit gene NMDAR2B (366C/G), the serotonin transporter gene (5HTTL-PR), the dopamine transporter gene DAT1(SLC6A3), the dopamine D2 receptor gene DRD2 TaqI A, or the GABAA alpha1(A15G), alpha6(T1519C), and gamma2(G3145A) subunit genes.	0.035190431	2004	GRIN2B	12	13866194	C	T
rs34315573	15542698	55885	LMO3	umls:C0001973	BeFree	PCR-based assays showed that alcoholism was associated with polymorphisms of the dopamine D2 receptor (DRD2) TaqI B (P = .029) and the GABAA-beta2 subunit C1412T (P = .012) genes, but not with the glutamate receptor subunit gene NMDAR2B (366C/G), the serotonin transporter gene (5HTTL-PR), the dopamine transporter gene DAT1(SLC6A3), the dopamine D2 receptor gene DRD2 TaqI A, or the GABAA alpha1(A15G), alpha6(T1519C), and gamma2(G3145A) subunit genes.	0.001628651	2004	GRIN2B	12	13866194	C	T
rs34315573	15542698	1813	DRD2	umls:C0001973	BeFree	PCR-based assays showed that alcoholism was associated with polymorphisms of the dopamine D2 receptor (DRD2) TaqI B (P = .029) and the GABAA-beta2 subunit C1412T (P = .012) genes, but not with the glutamate receptor subunit gene NMDAR2B (366C/G), the serotonin transporter gene (5HTTL-PR), the dopamine transporter gene DAT1(SLC6A3), the dopamine D2 receptor gene DRD2 TaqI A, or the GABAA alpha1(A15G), alpha6(T1519C), and gamma2(G3145A) subunit genes.	0.203722004	2004	GRIN2B	12	13866194	C	T
rs34315573	15542698	2904	GRIN2B	umls:C0001973	BeFree	PCR-based assays showed that alcoholism was associated with polymorphisms of the dopamine D2 receptor (DRD2) TaqI B (P = .029) and the GABAA-beta2 subunit C1412T (P = .012) genes, but not with the glutamate receptor subunit gene NMDAR2B (366C/G), the serotonin transporter gene (5HTTL-PR), the dopamine transporter gene DAT1(SLC6A3), the dopamine D2 receptor gene DRD2 TaqI A, or the GABAA alpha1(A15G), alpha6(T1519C), and gamma2(G3145A) subunit genes.	0.021279544	2004	GRIN2B	12	13866194	C	T
rs35951	24962325	54622	ARL15	umls:C0001973	GWASCAT	We also identified intronic SNPs in the ADP-ribosylation factor like 15 (ARL15) gene on chromosome 5 (P=1.11×10(-8)) and the UTP20 small subunit (UTP20) gene on chromosome 12 (P=4.32×10(-8)) that were associated with age at onset of AD.	0.120271442	2014	ARL15	5	54296531	G	T
rs3762894	21083667	127	ADH4	umls:C0001973	BeFree	The ADH4 SNP rs3762894 was associated with AD in Plains Indians.	0.015092462	2011	ADH4;LOC100507053	4	99144933	T	C
rs3771829	24817687	6869	TACR1	umls:C0001973	BeFree	To further elucidate the role of TACR1 in affective disorders, rs3771829 was genotyped in a second BPAD sample of 593 subjects (UCL2), in 997 subjects with ADS, and a subsample of 143 individuals diagnosed with BPAD and comorbid alcohol dependence (BPALC).	0.123724241	2014	TACR1	2	75137019	C	G
rs3771829	19204064	6869	TACR1	umls:C0001973	BeFree	Four single-nucleotide polymorphisms (rs3771829, rs3771833, rs3771856, and rs1701137) at the TACR1 gene, previously known to be associated with bipolar disorder or alcoholism, were strongly associated with ADHD.	0.123724241	2010	TACR1	2	75137019	C	G
rs3771833	19204064	6869	TACR1	umls:C0001973	BeFree	Four single-nucleotide polymorphisms (rs3771829, rs3771833, rs3771856, and rs1701137) at the TACR1 gene, previously known to be associated with bipolar disorder or alcoholism, were strongly associated with ADHD.	0.123724241	2010	TACR1	2	75139811	C	T
rs3771856	19204064	6869	TACR1	umls:C0001973	BeFree	Four single-nucleotide polymorphisms (rs3771829, rs3771833, rs3771856, and rs1701137) at the TACR1 gene, previously known to be associated with bipolar disorder or alcoholism, were strongly associated with ADHD.	0.123724241	2010	TACR1;LOC105374811;LOC105374812	2	75186888	G	A
rs3782025	23757001	6532	SLC6A4	umls:C0001973	BeFree	Subsequent analysis of these two interaction models revealed an OR of 2.71 and 2.80, respectively, for AD (P < 0.001) in carriers of genotype combinations 5'-HTTLPR:LL/LS(SLC6A4)-rs1042173:TT/TG(SLC6A4)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B) and 5'-HTTLPR:LL/LS(SLC6A4)-rs10160548:GT/TT(HTR3A)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B).	0.215482118	2013	HTR3B	11	113936885	G	A
rs3782025	23757001	3359	HTR3A	umls:C0001973	BeFree	Subsequent analysis of these two interaction models revealed an OR of 2.71 and 2.80, respectively, for AD (P < 0.001) in carriers of genotype combinations 5'-HTTLPR:LL/LS(SLC6A4)-rs1042173:TT/TG(SLC6A4)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B) and 5'-HTTLPR:LL/LS(SLC6A4)-rs10160548:GT/TT(HTR3A)-rs1176744:AC(HTR3B)-rs3782025:AG(HTR3B).	0.003181358	2013	HTR3B	11	113936885	G	A
rs3814964	NA	4676	NAP1L4	umls:C0001973	GAD	NA	0.004734064	NA	NAP1L4	11	2978277	G	T
rs3827730	22064162	11124	FAF1	umls:C0001973	GAD	[These results underscore the complex genomic influences on psychiatric phenotypes and suggest that a comorbid phenotype is partially influenced by genetic variants that do not affect AD alone.]	0.004734064	2012	FAF1;LOC105378715	1	50472176	T	C
rs3827730	NA	11124	FAF1	umls:C0001973	GAD	NA	0.004734064	NA	FAF1;LOC105378715	1	50472176	T	C
rs386539811	12215082	4852	NPY	umls:C0001973	BeFree	A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States.	0.219088146	2002	NA	NA	NA	NA	NA
rs386539811	15654286	847	CAT	umls:C0001973	BeFree	Four polymorphisms were evaluated, including the serotonin transporter HTTLPR promoter ins/del, GABAAalpha6 Pro385Ser, NPY Leu7Pro, and catalase 262C>T. Two of these, HTTLPR and GABAAalpha6 Pro385Ser, had been previously associated with LR and alcoholism in a preliminary study.	0.000814326	2005	NA	NA	NA	NA	NA
rs386539811	15654286	4852	NPY	umls:C0001973	BeFree	Four polymorphisms were evaluated, including the serotonin transporter HTTLPR promoter ins/del, GABAAalpha6 Pro385Ser, NPY Leu7Pro, and catalase 262C>T. Two of these, HTTLPR and GABAAalpha6 Pro385Ser, had been previously associated with LR and alcoholism in a preliminary study.	0.219088146	2005	NA	NA	NA	NA	NA
rs386539811	12544000	4852	NPY	umls:C0001973	BeFree	NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations.	0.219088146	2003	NA	NA	NA	NA	NA
rs386602118	23023098	627	BDNF	umls:C0001973	BeFree	In conclusion, these data do not support the view that BDNF Val66Met polymorphism correlates with the specific alcohol related phenotypes in ethnically homogenous medication-free Caucasian subjects with alcohol dependence.	0.011715608	2013	NA	NA	NA	NA	NA
rs386602118	19170664	627	BDNF	umls:C0001973	BeFree	Association between Val66Met brain-derived neurotrophic factor (BDNF) gene polymorphism and post-treatment relapse in alcohol dependence.	0.011715608	2009	NA	NA	NA	NA	NA
rs386602118	25650137	627	BDNF	umls:C0001973	BeFree	This study indicates a possible effect of BDNF Val66Met on alcohol addiction-related phenotypes in adolescence.	0.011715608	2014	NA	NA	NA	NA	NA
rs386602118	15896496	627	BDNF	umls:C0001973	BeFree	A study of the association of (Val66Met) polymorphism in the brain-derived neurotrophic factor gene with alcohol dependence and extreme violence in Chinese males.	0.011715608	2005	NA	NA	NA	NA	NA
rs386602118	23582695	627	BDNF	umls:C0001973	BeFree	These results suggest that the BDNF Val66Met polymorphism may contribute to alcohol dependence vulnerability via lower EFs performance.	0.011715608	2013	NA	NA	NA	NA	NA
rs386602118	21640793	627	BDNF	umls:C0001973	BeFree	The BDNF polymorphism Val66Met (rs6265) has been studied in the context of etiology of mental diseases including alcoholism.	0.011715608	2011	NA	NA	NA	NA	NA
rs386602276	23321485	3356	HTR2A	umls:C0001973	BeFree	However, the potential association between the T102C polymorphism (rs6313) in the type 2A serotonin receptor (HTR2A) gene and treatment outcomes in alcohol dependence has not been investigated.	0.146113297	2013	NA	NA	NA	NA	NA
rs386602276	17713649	3356	HTR2A	umls:C0001973	BeFree	T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism.	0.146113297	2007	NA	NA	NA	NA	NA
rs386602276	22661198	3356	HTR2A	umls:C0001973	BeFree	The results suggest a potential role of the T102C HTR2A polymorphism in development of alcohol dependence.	0.146113297	2012	NA	NA	NA	NA	NA
rs3930234	21529783	8646	CHRD	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	LOC105374252	3	184498342	T	C
rs4147541	24889829	125	ADH1B	umls:C0001973	BeFree	Three mQTLs (rs2173201, rs4147542, and rs4147541 in ADH1B-AHD1C gene cluster region) found in AAs were previously identified by our genome-wide association studies as being significantly associated with AD in AAs.	0.347415629	2014	ADH1C	4	99353000	G	C
rs4147542	24889829	125	ADH1B	umls:C0001973	BeFree	Three mQTLs (rs2173201, rs4147542, and rs4147541 in ADH1B-AHD1C gene cluster region) found in AAs were previously identified by our genome-wide association studies as being significantly associated with AD in AAs.	0.347415629	2014	ADH1C	4	99347396	T	C
rs4293630	21529783	1291	COL6A1	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	NA	21	46025877	A	G
rs4478858	23455491	347735	SERINC2	umls:C0001973	GWASCAT	NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.	0.120542884	2013	SERINC2	1	31411078	T	C
rs4532	24135011	1814	DRD3	umls:C0001973	BeFree	In the absence of genetic data from Indian population, we evaluated genetic association of three polymorphisms namely rs4532 in DRD1, rs6280 in DRD3 and 120 bp duplication in 1.2 kb upstream region of DRD4 with AD.	0.009901391	2013	DRD1	5	175443147	C	T
rs4605456	NA	4685	NCAM2	umls:C0001973	GAD	NA	0.004734064	NA	NCAM2	21	21264514	C	T
rs463379	19352220	6531	SLC6A3	umls:C0001973	BeFree	The present findings suggest that DAT1 genetic variation influences drinking behavior in our Finnish population, where the rs6350 A and rs463379 G alleles provide a protective role against high alcohol consumption and alcohol dependence, respectively.	0.035190431	2009	SLC6A3	5	1431049	G	C
rs4680	22474103	1312	COMT	umls:C0001973	BeFree	Reduced dopamine receptor sensitivity as an intermediate phenotype in alcohol dependence and the role of the COMT Val158Met and DRD2 Taq1A genotypes.	0.157100455	2012	COMT;MIR4761	22	19963748	G	A
rs4680	19023276	1312	COMT	umls:C0001973	GAD	[We evaluated the association of COMT genotype at this locus with blood pressure (BP) in 839 alcohol-dependent individuals before and during participation in an alcoholism treatment trial.]	0.157100455	2009	COMT;MIR4761	22	19963748	G	A
rs4680	22509987	1312	COMT	umls:C0001973	BeFree	COMT Val158Met modulates the effect of childhood adverse experiences on the risk of alcohol dependence.	0.157100455	2013	COMT;MIR4761	22	19963748	G	A
rs4680	22509987	1813	DRD2	umls:C0001973	BeFree	This study tested the hypothesis that genetic variation in COMT Val158Met and DRD2/ANKK1 Taq1A interacts with childhood adverse experiences to predict alcohol dependence.	0.203722004	2013	COMT;MIR4761	22	19963748	G	A
rs4680	15584875	4988	OPRM1	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.159066562	2004	COMT;MIR4761	22	19963748	G	A
rs4680	22474103	1813	DRD2	umls:C0001973	BeFree	COMT Val158Met and DRD2 Taq1A may confer their risk of alcohol dependence through reduced dopamine receptor sensitivity in the prefrontal cortex and hindbrain, respectively.	0.203722004	2012	COMT;MIR4761	22	19963748	G	A
rs4680	15584875	125	ADH1B	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.347415629	2004	COMT;MIR4761	22	19963748	G	A
rs4680	17079080	6532	SLC6A4	umls:C0001973	BeFree	The paper focuses on such candidate gene polymorphisms that alter alcoholism-related intermediate phenotypes including: dopaminergic system polymorphic variants (DRD2 -141C Ins/Del in promoter region, exon 8 and DRD2 TaqI A and DAT 40bp VNTR genes polymorphisms) that cause predisposition to severe alcoholism (haplotype Ins/G/A2); COMT Val158Met gene polymorphism related to differences in executive cognitive function and 5-HTT gene promoter polymorphism, which alters stress response and affects anxiety and dysphoria.	0.215482118	2006	COMT;MIR4761	22	19963748	G	A
rs4680	16499480	1312	COMT	umls:C0001973	BeFree	Sex differences in the influence of COMT Val158Met on alcoholism and smoking in plains American Indians.	0.157100455	2006	COMT;MIR4761	22	19963748	G	A
rs4680	15584875	1312	COMT	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.157100455	2004	COMT;MIR4761	22	19963748	G	A
rs4707535	NA	2570	GABRR2	umls:C0001973	GAD	NA	0.002638474	NA	GABRR2	6	89268187	T	C
rs4758533	NA	114879	OSBPL5	umls:C0001973	GAD	NA	0.005005506	NA	OSBPL5	11	3128856	A	G
rs4770403	22004471	6445	SGCG	umls:C0001973	GAD	[Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.]	0.002367032	2012	SGCG	13	23180988	G	A
rs4813680	NA	146	ADRA1D	umls:C0001973	GAD	NA	0.002638474	NA	NA	20	4259770	C	A
rs4961280	25495208	50628	GEMIN4	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	AGO2	8	140637315	C	A
rs4961280	25495208	26523	AGO1	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	AGO2	8	140637315	C	A
rs4961280	25495208	27161	AGO2	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	AGO2	8	140637315	C	A
rs4966017	NA	3480	IGF1R	umls:C0001973	GAD	NA	0.004734064	NA	IGF1R	15	98724404	T	G
rs523349	22707254	6716	SRD5A2	umls:C0001973	BeFree	In this study, we explored whether functionally relevant genetic polymorphisms in SRD5A2 (V89L, A49T, [TA](n)) are linked to alcohol addiction and craving.	0.000271442	2012	SRD5A2	2	31580636	G	C
rs528301	22488850	6496	SIX3	umls:C0001973	GAD	[Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.]	0.004734064	2012	NA	2	44927769	G	A
rs528301	22488850	79823	CAMKMT	umls:C0001973	GAD	[Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.]	0.002367032	2012	NA	2	44927769	G	A
rs5443	16897596	2784	GNB3	umls:C0001973	BeFree	The GNB3 C825T polymorphism and depression among subjects with alcohol dependence.	0.002638474	2007	GNB3;CDCA3	12	6845711	C	T
rs55868078	25410943	125	ADH1B	umls:C0001973	BeFree	We tested the most significant ADH1B single nucleotide polymorphisms for alcohol dependence from a genomewide association study with this sample, ADH1B-rs1229984 (Arg48His) and ADH1B-rs2066702 (Arg370Cys), in EA and AA subsamples, respectively.	0.347415629	2014	NA	NA	NA	NA	NA
rs57083693	24962325	27340	UTP20	umls:C0001973	GWASCAT	We also identified intronic SNPs in the ADP-ribosylation factor like 15 (ARL15) gene on chromosome 5 (P=1.11×10(-8)) and the UTP20 small subunit (UTP20) gene on chromosome 12 (P=4.32×10(-8)) that were associated with age at onset of AD.	0.120271442	2014	UTP20	12	101348402	T	C
rs578776	20485328	1138	CHRNA5	umls:C0001973	BeFree	We also observed two SNPs associated with alcohol dependence, that is, rs615470 in CHRNA5 (OR=0.77, P=0.0006) and rs578776 (OR=0.78, P=0.001).	0.132649486	2010	CHRNA3	15	78596058	G	A
rs5922838	22064162	5456	POU3F4	umls:C0001973	GAD	[These results underscore the complex genomic influences on psychiatric phenotypes and suggest that a comorbid phenotype is partially influenced by genetic variants that do not affect AD alone.]	0.002367032	2012	NA	X	83616187	A	G
rs595961	25495208	50628	GEMIN4	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	AGO1	1	35902179	A	G
rs595961	25495208	26523	AGO1	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	AGO1	1	35902179	A	G
rs595961	25495208	27161	AGO2	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	AGO1	1	35902179	A	G
rs5968205	22064162	5456	POU3F4	umls:C0001973	GAD	[These results underscore the complex genomic influences on psychiatric phenotypes and suggest that a comorbid phenotype is partially influenced by genetic variants that do not affect AD alone.]	0.002367032	2012	NA	X	83699482	C	T
rs615470	20485328	1138	CHRNA5	umls:C0001973	BeFree	We also observed two SNPs associated with alcohol dependence, that is, rs615470 in CHRNA5 (OR=0.77, P=0.0006) and rs578776 (OR=0.78, P=0.001).	0.132649486	2010	CHRNA3;CHRNA5	15	78593646	T	C
rs6265	21640793	627	BDNF	umls:C0001973	BeFree	The BDNF polymorphism Val66Met (rs6265) has been studied in the context of etiology of mental diseases including alcoholism.	0.011715608	2011	BDNF;BDNF-AS	11	27658369	C	T
rs6280	24776816	1814	DRD3	umls:C0001973	BeFree	DRD3 gene rs6280 polymorphism may be associated with alcohol dependence overall and with Lesch type I alcohol dependence in Koreans.	0.009901391	2013	DRD3	3	114171968	C	T
rs6280	24135011	1814	DRD3	umls:C0001973	BeFree	In the absence of genetic data from Indian population, we evaluated genetic association of three polymorphisms namely rs4532 in DRD1, rs6280 in DRD3 and 120 bp duplication in 1.2 kb upstream region of DRD4 with AD.	0.009901391	2013	DRD3	3	114171968	C	T
rs6296	22550993	6532	SLC6A4	umls:C0001973	BeFree	Our study suggests that neither the 5-HTTLPR gene nor the 5-HT1B G861C polymorphism alone is a risk factor for antisocial alcoholism in Taiwan's Han Chinese population, but that the interaction between both genes may increase susceptibility to antisocial alcoholism.	0.215482118	2012	HTR1B;LOC105377864	6	77462543	C	G
rs6296	12496953	3351	HTR1B	umls:C0001973	BeFree	No significant association of the genotype or allele frequencies of the h5-HTR(1B) G861C locus was observed with diagnoses of alcoholism, bipolar disorder, schizophrenia or a history of a suicide attempt.	0.020912294	2003	HTR1B;LOC105377864	6	77462543	C	G
rs6313	23321485	3356	HTR2A	umls:C0001973	BeFree	However, the potential association between the T102C polymorphism (rs6313) in the type 2A serotonin receptor (HTR2A) gene and treatment outcomes in alcohol dependence has not been investigated.	0.146113297	2013	HTR2A	13	46895805	G	A
rs6313	17713649	3356	HTR2A	umls:C0001973	BeFree	T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism.	0.146113297	2007	HTR2A	13	46895805	G	A
rs6313	22661198	3356	HTR2A	umls:C0001973	BeFree	The results suggest a potential role of the T102C HTR2A polymorphism in development of alcohol dependence.	0.146113297	2012	HTR2A	13	46895805	G	A
rs6318	14574222	3358	HTR2C	umls:C0001973	BeFree	In our sample, the functional relevant 5-HTT promoter and the 5-HT2c receptor Cys23Ser polymorphism do not contribute to the supposed common genetic predisposition of ADHD and alcohol dependence.	0.003724241	2003	HTR2C;LOC105373313	X	114731326	C	G
rs6318	14574222	6532	SLC6A4	umls:C0001973	BeFree	In our sample, the functional relevant 5-HTT promoter and the 5-HT2c receptor Cys23Ser polymorphism do not contribute to the supposed common genetic predisposition of ADHD and alcohol dependence.	0.215482118	2003	HTR2C;LOC105373313	X	114731326	C	G
rs6318	10494451	3358	HTR2C	umls:C0001973	BeFree	This finding suggests that 5-HT2C receptors are involved in the regulation of norepinephrine turnover in humans; however, HTR2C Cys23Ser does not appear to contribute to the risk of alcoholism, or its contribution to this complex and heterogenous disorder is too small to be detected by a sample of this size and structure.	0.003724241	1999	HTR2C;LOC105373313	X	114731326	C	G
rs6318	10994642	3358	HTR2C	umls:C0001973	BeFree	5-HT2C Cys23Ser allele frequencies and genotypes did not differ among patients with alcohol dependence, panic disorder, generalized anxiety disorder, narcolepsy and normal healthy volunteers.	0.003724241	2000	HTR2C;LOC105373313	X	114731326	C	G
rs6350	19352220	6531	SLC6A3	umls:C0001973	BeFree	The present findings suggest that DAT1 genetic variation influences drinking behavior in our Finnish population, where the rs6350 A and rs463379 G alleles provide a protective role against high alcohol consumption and alcohol dependence, respectively.	0.035190431	2009	SLC6A3	5	1443084	G	C,A
rs6356	15722952	7054	TH	umls:C0001973	BeFree	Tyrosine hydroxylase Val-81-Met polymorphism associated with early-onset alcoholism.	0.003995683	2005	TH	11	2169721	C	T
rs637547	21445666	154215	NKAIN2	umls:C0001973	BeFree	Interestingly, four SNPs in DSCAML1 at 11q23 reached the genome-wide significance (the top SNP is rs10892169 with P = 5.31 × 10(-9)), while rs637547 in NKAIN2 at 6q21 showed strong association with AD (P = 5.11 × 10(-7)) in the replication sample.	0.000271442	2011	NKAIN2	6	124589242	A	C
rs637547	21445666	57453	DSCAML1	umls:C0001973	BeFree	Interestingly, four SNPs in DSCAML1 at 11q23 reached the genome-wide significance (the top SNP is rs10892169 with P = 5.31 × 10(-9)), while rs637547 in NKAIN2 at 6q21 showed strong association with AD (P = 5.11 × 10(-7)) in the replication sample.	0.002638474	2011	NKAIN2	6	124589242	A	C
rs6447493	24166645	2555	GABRA2	umls:C0001973	BeFree	We genotyped subjects for three SNPs previously associated with AD: rs279858 in GABRA2, and rs7654165 and rs6447493 in GABRG1.	0.171173163	2014	GABRG1	4	46040928	C	T
rs6483362	20202923	2915	GRM5	umls:C0001973	GAD	[A genome-wide association study of alcohol dependence.]	0.002367032	2010	GRM5	11	88679283	A	G
rs6691840	23006490	2917	GRM7	umls:C0001973	BeFree	The aim of this study was to evaluate the role of the glutamate receptor subunit-7 (GluR7, GRIK 3) rs6691840 (Ser310Ala, T928G) in the pathogenesis of alcohol dependence (AD).	0.002638474	2013	GRIK3	1	36859876	A	C,G
rs6691840	16356644	2899	GRIK3	umls:C0001973	BeFree	Family-based and case-control association studies of glutamate receptor GRIK3 Ser310Ala polymorphism in Polish patients and families with alcohol dependence.	0.00764398	2006	GRIK3	1	36859876	A	C,G
rs6691840	23006490	2899	GRIK3	umls:C0001973	BeFree	Family-based and case-control study of glutamate receptor GRIK3 Ser310Ala polymorphism in alcohol dependence.	0.00764398	2013	GRIK3	1	36859876	A	C,G
rs6701037	21703634	63923	TNN	umls:C0001973	GAD	[, we identified three new loci (KIAA0040, THSD7B and NRD1) and confirmed the previous association of PKNOX2 with alcohol dependence.]	0.002367032	2011	NA	1	175150943	A	C
rs671	23969552	217	ALDH2	umls:C0001973	BeFree	Genetic polymorphisms of alcohol dehydrogenase-1B (ADH1B, rs1229984) and aldehyde dehydrogenase-2 (ALDH2, rs671) affect ethanol (EtOH) metabolism and susceptibility to alcoholism.	0.470944373	2014	ALDH2	12	111803962	G	A
rs671	24277619	217	ALDH2	umls:C0001973	GWASCAT	ALDH2 is associated to alcohol dependence and is the major genetic determinant of daily maximum drinks in a GWAS study of an isolated rural Chinese sample.	0.470944373	2013	ALDH2	12	111803962	G	A
rs671	NA	217	ALDH2	umls:C0001973	CLINVAR	NA	0.470944373	NA	ALDH2	12	111803962	G	A
rs671	23969552	125	ADH1B	umls:C0001973	BeFree	Genetic polymorphisms of alcohol dehydrogenase-1B (ADH1B, rs1229984) and aldehyde dehydrogenase-2 (ALDH2, rs671) affect ethanol (EtOH) metabolism and susceptibility to alcoholism.	0.347415629	2014	ALDH2	12	111803962	G	A
rs6716455	21529783	27249	MMADHC	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	LOC105373684	2	150269889	G	A
rs6902771	19581569	2099	ESR1	umls:C0001973	GAD	[This is the first GWAS and follow-up study to identify a genome-wide significant association in alcohol dependence. Further independent studies are required to confirm these findings.]	0.002367032	2009	ESR1	6	151836746	C	T
rs7279496	NA	4685	NCAM2	umls:C0001973	GAD	NA	0.004734064	NA	NCAM2	21	21307316	C	A
rs728115	22488850	3751	KCND2	umls:C0001973	GAD	[Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.]	0.002367032	2012	KCND2	7	120665095	G	A
rs729662	NA	833	CARS	umls:C0001973	GAD	NA	0.004734064	NA	CARS	11	3006910	G	A
rs7301328	15542698	1813	DRD2	umls:C0001973	BeFree	PCR-based assays showed that alcoholism was associated with polymorphisms of the dopamine D2 receptor (DRD2) TaqI B (P = .029) and the GABAA-beta2 subunit C1412T (P = .012) genes, but not with the glutamate receptor subunit gene NMDAR2B (366C/G), the serotonin transporter gene (5HTTL-PR), the dopamine transporter gene DAT1(SLC6A3), the dopamine D2 receptor gene DRD2 TaqI A, or the GABAA alpha1(A15G), alpha6(T1519C), and gamma2(G3145A) subunit genes.	0.203722004	2004	GRIN2B	12	13865843	G	C,T
rs7301328	15542698	6531	SLC6A3	umls:C0001973	BeFree	PCR-based assays showed that alcoholism was associated with polymorphisms of the dopamine D2 receptor (DRD2) TaqI B (P = .029) and the GABAA-beta2 subunit C1412T (P = .012) genes, but not with the glutamate receptor subunit gene NMDAR2B (366C/G), the serotonin transporter gene (5HTTL-PR), the dopamine transporter gene DAT1(SLC6A3), the dopamine D2 receptor gene DRD2 TaqI A, or the GABAA alpha1(A15G), alpha6(T1519C), and gamma2(G3145A) subunit genes.	0.035190431	2004	GRIN2B	12	13865843	G	C,T
rs7301328	15542698	2904	GRIN2B	umls:C0001973	BeFree	PCR-based assays showed that alcoholism was associated with polymorphisms of the dopamine D2 receptor (DRD2) TaqI B (P = .029) and the GABAA-beta2 subunit C1412T (P = .012) genes, but not with the glutamate receptor subunit gene NMDAR2B (366C/G), the serotonin transporter gene (5HTTL-PR), the dopamine transporter gene DAT1(SLC6A3), the dopamine D2 receptor gene DRD2 TaqI A, or the GABAA alpha1(A15G), alpha6(T1519C), and gamma2(G3145A) subunit genes.	0.021279544	2004	GRIN2B	12	13865843	G	C,T
rs7301328	15542698	55885	LMO3	umls:C0001973	BeFree	PCR-based assays showed that alcoholism was associated with polymorphisms of the dopamine D2 receptor (DRD2) TaqI B (P = .029) and the GABAA-beta2 subunit C1412T (P = .012) genes, but not with the glutamate receptor subunit gene NMDAR2B (366C/G), the serotonin transporter gene (5HTTL-PR), the dopamine transporter gene DAT1(SLC6A3), the dopamine D2 receptor gene DRD2 TaqI A, or the GABAA alpha1(A15G), alpha6(T1519C), and gamma2(G3145A) subunit genes.	0.001628651	2004	GRIN2B	12	13865843	G	C,T
rs738409	22704398	80339	PNPLA3	umls:C0001973	BeFree	Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) genetic variant has been associated with hepatocellular carcinoma (HCC) in individuals with chronic alcohol abuse or hepatic viral infection.	0.002638474	2012	PNPLA3	22	43928847	C	G
rs7481584	NA	833	CARS	umls:C0001973	GAD	NA	0.004734064	NA	CARS	11	3007859	G	A
rs75012854	15584875	125	ADH1B	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.347415629	2004	COMT;MIR4761	22	19962641	A	G
rs75012854	15584875	4988	OPRM1	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.159066562	2004	COMT;MIR4761	22	19962641	A	G
rs75012854	15584875	1312	COMT	umls:C0001973	BeFree	Functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1B and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-O-methyltransferase (COMT) Val158Met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (OPRM1) Asn40Asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and HTTLPR, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse.	0.157100455	2004	COMT;MIR4761	22	19962641	A	G
rs750338	21703634	63876	PKNOX2	umls:C0001973	GAD	[In conclusion, we identified three new loci (KIAA0040, THSD7B and NRD1) and confirmed the previous association of PKNOX2 with alcohol dependence.]	0.130011012	2011	PKNOX2	11	125302697	A	G
rs750338	21703634	63876	PKNOX2	umls:C0001973	GWASCAT	In conclusion, we identified three new loci (KIAA0040, THSD7B and NRD1) and confirmed the previous association of PKNOX2 with alcohol dependence.	0.130011012	2011	PKNOX2	11	125302697	A	G
rs750338	20202923	63876	PKNOX2	umls:C0001973	GAD	[A genome-wide association study of alcohol dependence.]	0.130011012	2010	PKNOX2	11	125302697	A	G
rs752949	15542698	10327	AKR1A1	umls:C0001973	BeFree	The genotype for the most active alcohol dehydrogenase enzyme ADH1C was associated with a lower risk of alcoholism (P = .026) and was less prevalent in alcoholics with DRD2TaqIA2/A2 (P = .047), GABAA-beta2 1412C/C (P = .01), or EAAT2 603G/A (P = .022) genotypes.	0.015200745	2004	SLC1A2	11	35306201	C	T
rs752949	15542698	6506	SLC1A2	umls:C0001973	BeFree	Combined DRD2TaqI A or B with GABAA-beta2 or EAAT2 G603A genotypes may have a concerted influence in the predisposition to alcoholism.	0.002909916	2004	SLC1A2	11	35306201	C	T
rs752949	15542698	126	ADH1C	umls:C0001973	BeFree	The genotype for the most active alcohol dehydrogenase enzyme ADH1C was associated with a lower risk of alcoholism (P = .026) and was less prevalent in alcoholics with DRD2TaqIA2/A2 (P = .047), GABAA-beta2 1412C/C (P = .01), or EAAT2 603G/A (P = .022) genotypes.	0.195114925	2004	SLC1A2	11	35306201	C	T
rs7590720	19581569	55825	PECR	umls:C0001973	GAD	[Genome-wide association study of alcohol dependence.]	0.122638474	2009	NA	2	216033935	G	A
rs7590720	19581569	55825	PECR	umls:C0001973	GWASCAT	Genome-wide association study of alcohol dependence.	0.122638474	2009	NA	2	216033935	G	A
rs7590720	19581569	55686	MREG	umls:C0001973	GAD	[This is the first GWAS and follow-up study to identify a genome-wide significant association in alcohol dependence. Further independent studies are required to confirm these findings.]	0.005005506	2009	NA	2	216033935	G	A
rs7654165	24166645	2555	GABRA2	umls:C0001973	BeFree	We genotyped subjects for three SNPs previously associated with AD: rs279858 in GABRA2, and rs7654165 and rs6447493 in GABRG1.	0.171173163	2014	GABRG1	4	46125050	C	T
rs768048	21529783	1630	DCC	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	DCC	18	52759028	C	T
rs8040009	21529783	145858	C15orf32	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.122367032	2011	C15orf32	15	92501109	T	C
rs8040009	21529783	145858	C15orf32	umls:C0001973	GWASCAT	A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.	0.122367032	2011	C15orf32	15	92501109	T	C
rs8062326	21876473	162073	ITPRIPL2	umls:C0001973	GAD	[We have confirmed the role of some genes previously shown to be associated with alcoholism in the comorbid bipolar alcoholism subgroup. In this subgroup, bipolar disorder may lower the threshold for the phenotypic expression of these alcoholism susceptibi]	0.002367032	2011	NA	16	19144694	G	A
rs8111589	22064162	80207	OPA3	umls:C0001973	GAD	[These results underscore the complex genomic influences on psychiatric phenotypes and suggest that a comorbid phenotype is partially influenced by genetic variants that do not affect AD alone.]	0.002638474	2012	OPA3	19	45531300	C	T
rs8115863	NA	146	ADRA1D	umls:C0001973	GAD	NA	0.002638474	NA	NA	20	4259862	T	C
rs8126935	NA	4685	NCAM2	umls:C0001973	GAD	NA	0.004734064	NA	NCAM2	21	21315260	A	G
rs8127865	NA	4685	NCAM2	umls:C0001973	GAD	NA	0.004734064	NA	NCAM2	21	21271400	A	G
rs910924	25495208	26523	AGO1	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	GEMIN4;DBIL5P	17	752680	G	A
rs910924	25495208	27161	AGO2	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	GEMIN4;DBIL5P	17	752680	G	A
rs910924	25495208	50628	GEMIN4	umls:C0001973	BeFree	We found that AGO1 rs595961 (χ(2) = 9.066, p = 0.003; odds ratio [OR] = 0.459, 95% confidence interval [CI]: 0.275-0.768) and AGO2 rs4961280 (χ(2) = 4.111, p = 0.043; OR = 0.590, 95% CI: 0.353-0.986) G alleles have significantly altered the risk for AD, and also there is a significant association of GEMIN4 rs910924 (χ(2) = 5.291, p = 0.021; OR = 1.913, 95% CI: 1.094-3.344) T allele with the risk for AD.	0.000271442	2015	GEMIN4;DBIL5P	17	752680	G	A
rs9282858	22707254	6716	SRD5A2	umls:C0001973	BeFree	In this study, we explored whether functionally relevant genetic polymorphisms in SRD5A2 (V89L, A49T, [TA](n)) are linked to alcohol addiction and craving.	0.000271442	2012	SRD5A2	2	31580756	C	T
rs9291283	24687270	2555	GABRA2	umls:C0001973	BeFree	Although the analysis provided nominal support for an association with rs9291283 and AAD in adulthood and CD in adolescence, the current study failed to replicate previous associations between two well replicated GABRA2 SNPs and CD and alcohol dependence.	0.171173163	2014	GABRA2	4	46369816	G	A
rs933769	21529783	55784	MCTP2	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	NA	15	95509513	C	T
rs9416295	NA	4153	MBL2	umls:C0001973	GAD	NA	0.002638474	NA	NA	10	53653356	T	C
rs9512637	21529783	387496	RASL11A	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.002367032	2011	NA	13	27346474	T	C
rs9556711	21529783	10150	MBNL2	umls:C0001973	GAD	[We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation acr]	0.122367032	2011	MBNL2	13	97364162	G	A
rs9556711	21529783	10150	MBNL2	umls:C0001973	GWASCAT	A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.	0.122367032	2011	MBNL2	13	97364162	G	A
rs9636231	21956439	11249	NXPH2	umls:C0001973	GAD	[Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.]	0.002367032	2012	LOC105373639	2	138914385	G	A
rs9939609	25265168	79068	FTO	umls:C0001973	BeFree	In conclusion, our study proves that there is an inverse association between rs9939609 polymorphism in FTO gene and completed suicide which is independent from association between FTO and alcohol addiction.	0.000814326	2014	FTO	16	53786615	T	A
rs9939609	21182554	79068	FTO	umls:C0001973	BeFree	Inverse association of the obesity predisposing FTO rs9939609 genotype with alcohol consumption and risk for alcohol dependence.	0.000814326	2011	FTO	16	53786615	T	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:3898)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	1110019	rs11260542	A	G	rs11260542	20201924	8.24E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	1173611	rs6697886	G	A	rs6697886	21703634	9.70E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	3744261	rs7545274	C	A	rs7545274	21314694	8.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	4295304	rs12132422	A	G	rs12132422	20201924	4.32E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	5795008	rs17028719	A	G	rs17028719	22096494	8.90E-07	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
1	6644723	rs731024	G	A	rs731024	24277619	4.58E-04	NA	0.41	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ZBTB48
1	6677064	rs10779795	A	G	rs10779795	24277619	8.53E-04	NA	0.38	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	PHF13
1	6764643	rs278020	C	T	rs278020	24277619	9.62E-04	NA	0.37	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
1	7363310	rs10489142	A	G	rs10489142	21314694	7.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	9000220	rs12091891	A	G	rs12091891	20201924	8.56E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	10232534	rs11121524	C	G	rs11121524	21314694	5.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	10655709	rs10864468	G	A	rs10864468	24962325	3.76E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10864468-A	Research Support, N.I.H., Extramural	G	PEX14
1	10658202	rs11121598	G	A	rs11121598	24962325	3.76E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11121598-A	Research Support, N.I.H., Extramural	G	PEX14
1	10666735	rs11121599	A	G	rs11121599	24962325	3.08E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11121599-A	Research Support, N.I.H., Extramural	A	PEX14
1	10668379	rs12722934	A	T	rs12722934	24962325	3.08E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs12722934-A	Research Support, N.I.H., Extramural	A	PEX14
1	10669098	rs6666075	C	G	rs6666075	24962325	3.08E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6666075-C	Research Support, N.I.H., Extramural	C	PEX14
1	10673094	rs3790630	C	T	rs3790630	24962325	6.83E-06	NA	1.32	[1.20-1.44]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs3790630-C	Research Support, N.I.H., Extramural	C	PEX14
1	10678488	rs284238	A	T	rs284238	24962325	1.61E-06	NA	1.4	[1.26-1.54]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284238-T	Research Support, N.I.H., Extramural	T	PEX14
1	10678610	rs284237	G	A	rs284237	24962325	2.08E-06	NA	1.4	[1.26-1.54]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284237-A	Research Support, N.I.H., Extramural	C	PEX14
1	10678843	rs284235	C	T	rs284235	24962325	7.11E-06	NA	1.38	[1.24-1.52]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284235-T	Research Support, N.I.H., Extramural	G	PEX14
1	10683683	rs190775	G	T	rs190775	24962325	2.39E-06	NA	1.41	[1.27-1.55]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs190775-T	Research Support, N.I.H., Extramural	C	PEX14
1	10687726	rs185864	G	C	rs185864	24962325	9.06E-07	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs185864-C	Research Support, N.I.H., Extramural	C	PEX14
1	10690883	rs284303	C	T	rs284303	24962325	9.06E-07	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284303-T	Research Support, N.I.H., Extramural	G	PEX14
1	10694125	rs284301	G	A	rs284301	24962325	1.12E-06	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284301-A	Research Support, N.I.H., Extramural	C	NA
1	10694907	rs61776290	C	T	rs61776290	24962325	2.00E-07	NA	1.48	[1.32-1.64]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs61776290-T	Research Support, N.I.H., Extramural	C	NA
1	10705880	rs284243	A	G	rs284243	24962325	2.90E-06	NA	1.37	[1.23-1.51]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284243-G	Research Support, N.I.H., Extramural	C	CASZ1
1	10708142	rs778228	A	G	rs778228	24962325	1.64E-06	NA	1.38	[1.24-1.52]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs778228-G	Research Support, N.I.H., Extramural	C	CASZ1
1	10709309	rs284300	C	G	rs284300	24962325	8.55E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284300-G	Research Support, N.I.H., Extramural	C	CASZ1
1	10710255	rs284298	G	A	rs284298	24962325	8.55E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284298-A	Research Support, N.I.H., Extramural	T	CASZ1
1	10712089	rs284296	A	G	rs284296	24962325	1.37E-06	NA	1.42	[1.28-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284296-G	Research Support, N.I.H., Extramural	C	CASZ1
1	10712097	rs284295	A	G	rs284295	24962325	1.37E-06	NA	1.42	[1.28-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284295-G	Research Support, N.I.H., Extramural	C	CASZ1
1	10714911	rs2242287	T	C	rs2242287	24962325	6.42E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2242287-C	Research Support, N.I.H., Extramural	G	CASZ1
1	10719566	rs476164	T	C	rs476164	24962325	7.42E-06	NA	1.38	[1.24-1.52]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs476164-C	Research Support, N.I.H., Extramural	G	CASZ1
1	10725498	rs284322	G	A	rs284322	24962325	5.54E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284322-A	Research Support, N.I.H., Extramural	C	CASZ1
1	10727020	rs284320	T	C	rs284320	24962325	2.02E-06	NA	1.38	[1.24-1.52]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs284320-C	Research Support, N.I.H., Extramural	A,G	CASZ1
1	10730002	rs11121604	A	G	rs11121604	24962325	3.11E-06	NA	1.43	[1.27-1.59]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11121604-G	Research Support, N.I.H., Extramural	A	CASZ1
1	10742120	rs61776326	G	A	rs61776326	24962325	7.20E-07	NA	1.45	[1.29-1.61]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs61776326-A	Research Support, N.I.H., Extramural	G	CASZ1
1	11043780	rs11121671	C	A,T	rs11121671	24277619	4.48E-04	NA	0.77	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
1	12598434	rs760943	T	C	rs760943	21529783	6.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	12684324	rs3010931	C	T	rs3010931	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	14585648	rs10928056	G	A	rs10928056	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	15743884	rs2496321	A	C	rs2496321	20201924	2.75E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	15744271	rs2496320	T	C	rs2496320	20201924	5.26E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	17869179	rs2477735	T	C	rs2477735	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	18236459	rs1339934	A	G	rs1339934	24277619	9.18E-04	NA	0.42	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
1	18392752	rs4920422	C	A	rs4920422	21314694	2.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	18528848	rs1033190	G	T	rs1033190	20201924	6.15E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	19056382	rs2743189	C	T	rs2743189	21314694	6.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	19284564	rs4912013	T	C	rs4912013	21314694	1.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	21725505	rs12736884	G	C	rs12736884	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	22537649	rs2473250	A	G	rs2473250	24277619	7.77E-04	NA	0.54	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
1	22954372	rs158761	C	A	rs158761	24277619	8.58E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
1	23266939	rs1832047	G	A	rs1832047	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	23794914	rs7522616	A	G	rs7522616	21703634	6.30E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	23942802	rs6677615	G	A	rs6677615	20201924	2.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	23942802	rs6677615	G	A	rs6677615	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24038231	rs11577033	T	C	rs11577033	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24038231	rs11577033	T	C	rs11577033	20201924	5.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24347103	rs7553231	T	C	rs7553231	20201924	2.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24347103	rs7553231	T	C	rs7553231	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24377326	rs11586125	T	C	rs11586125	20201924	4.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24377326	rs11586125	T	C	rs11586125	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24377944	rs7540557	T	C	rs7540557	20201924	2.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24377944	rs7540557	T	C	rs7540557	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24416133	rs4276859	C	T	rs4276859	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24416133	rs4276859	C	T	rs4276859	20201924	4.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	24475177	rs4648940	C	T	rs4648940	24277619	3.50E-05	NA	0.66	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
1	24532144	rs16860738	T	C	rs16860738	21314694	9.67E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	25193155	rs3131513	G	A	rs3131513	23942779	2.00E-06	NA	0.35	[NA] unit decrease	7,188 European ancestry individuals	European(7188)	ALL(7188)	EUR(7188)	ALL(7188)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs3131513-G	Twin Study	Research Support, N.I.H., Extramural	A
1	25467161	rs7530932	G	A	rs7530932	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	31881472	rs1039630	T	C	rs1039630	21703634	8.72E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	31883925	rs4478858	T	C	rs4478858	21703634	8.96E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	31883925	rs4478858	T	C	rs4478858	23455491	3.00E-08	NA	1.26	NA	1,409 European ancestry cases; 1,518 European ancestry controls	European(2927)	ALL(2927)	EUR(2927)	ALL(2927)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs4478858-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	31898234	rs4949402	T	C	rs4949402	21703634	9.44E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	31898536	rs2275435	C	T	rs2275435	21703634	9.53E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	33622077	rs676069	T	C	rs676069	21314694	7.10E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	33937135	rs10798953	T	C	rs10798953	19581569	2.04E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
1	34041191	rs6701268	T	G	rs6701268	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	34048268	rs416391	C	T	rs416391	20201924	3.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	34048268	rs416391	C	T	rs416391	20201924	4.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	34048268	rs416391	C	T	rs416391	pha002892	3.99E-05	phs000125	2.04	[1.45-2.86]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	CSMD2	intron	NM_052896
1	34181830	rs7533254	G	A	rs7533254	21314694	9.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	34375199	rs911216	A	C	rs911216	20201924	7.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	34379375	rs7536114	T	G	rs7536114	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	34479922	rs2358756	T	C	rs2358756	pha002893	2.73E-05	phs000125	1.79	[1.35-2.33]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	CSMD2	intron	NM_052896
1	34491558	rs2164581	A	G	rs2164581	pha002893	6.82E-05	phs000125	1.72	[1.32-2.27]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	CSMD2	intron	NM_052896
1	36653677	rs522468	T	G	rs522468	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	36789546	rs12116935	A	G	rs12116935	23691058	0.00000698	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	36822312	rs11583322	T	C	rs11583322	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	36822312	rs11583322	T	C	rs11583322	23691058	0.000000011	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	36831264	rs4451521	C	G	rs4451521	21314694	1.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	36874242	rs16822823	A	G	rs16822823	21314694	7.44E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	38161694	rs615530	A	G	rs615530	20201924	8.41E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	38173597	rs531454	A	G	rs531454	20201924	5.22E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	40503725	rs12402428	T	C	rs12402428	21314694	6.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	40531094	rs16826852	A	G	rs16826852	21314694	6.47E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	40549930	rs6688203	C	A	rs6688203	21314694	6.60E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	40601636	rs6600318	T	C	rs6600318	20201924	5.52E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	40628119	rs12074893	C	T	rs12074893	20201924	4.43E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	41484317	rs17357905	T	C	rs17357905	21314694	4.85E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	41666571	rs6672508	C	G	rs6672508	21314694	9.53E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	43540338	rs1198394	G	A	rs1198394	21314694	9.07E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	44062827	rs11582876	C	T	rs11582876	21314694	6.75E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	44469031	rs1362153	T	C	rs1362153	24962325	7.00E-06	NA	1.47	[1.29-1.65]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1362153-C	Research Support, N.I.H., Extramural	C	SLC6A9
1	47109328	rs1933932	C	T	rs1933932	21314694	8.90E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	47481616	rs9727862	G	A	rs9727862	20201924	5.82E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50590732	rs9436447	G	A	rs9436447	20201924	7.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50590732	rs9436447	G	A	rs9436447	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50882159	rs1278537	G	T	rs1278537	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50889255	rs1278530	G	A	rs1278530	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50889255	rs1278530	G	A	rs1278530	20201924	1.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50907438	rs4381241	T	C	rs4381241	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50907438	rs4381241	T	C	rs4381241	20201924	1.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50937848	rs3827730	T	C	rs3827730	20201924	1.40E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50937848	rs3827730	T	C	rs3827730	20201924	4.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	50937848	rs3827730	T	C	rs3827730	pha002892	1.42E-06	phs000125	1.57	[1.31-1.89]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	FAF1	intron	NM_007051
1	50937848	rs3827730	T	C	rs3827730	pha002893	4.08E-05	phs000125	1.56	[1.26-1.94]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	FAF1	intron	NM_007051
1	51174330	rs11205760	C	T	rs11205760	20201924	3.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	51174330	rs11205760	C	T	rs11205760	20201924	6.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	51174330	rs11205760	C	T	rs11205760	pha002892	3.37E-05	phs000125	1.47	[1.22-1.76]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	FAF1	intron	NM_007051
1	52258725	rs1004815	T	A,C,G	rs1004815	21703634	3.00E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	52263082	rs1417364	G	A	rs1417364	21703634	9.18E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	52324228	rs2842576	C	T	rs2842576	20202923	6.07E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	52324228	rs2842576	C	T	rs2842576	21703634	7.90E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	52324228	rs2842576	C	T	rs2842576	21956439	2.50E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	53344976	rs481440	C	T	rs481440	21314694	8.08E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	53792651	rs3820198	A	C	rs3820198	22096494	2.70E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
1	53808693	rs1416095	A	G	rs1416095	22096494	1.20E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
1	54198562	rs797913	C	T	rs797913	21314694	9.28E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	54199484	rs12075528	C	T	rs12075528	21314694	4.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	54756342	rs4927081	T	C	rs4927081	20201924	5.81E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	55107019	rs1368882	G	A	rs1368882	23942779	2.90E-04	NA	0.27	[NA] unit increase	7,188 European ancestry individuals	European(7188)	ALL(7188)	EUR(7188)	ALL(7188)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs1368882-A	Twin Study	Research Support, N.I.H., Extramural	T
1	56905445	rs6421495	T	A	rs6421495	21314694	4.09E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	57395251	rs605648	T	C	rs605648	24277619	8.94E-04	NA	0.77	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	C8B
1	57427251	rs856843	C	A	rs856843	21314694	9.96E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	57665932	rs17115341	C	T	rs17115341	21314694	7.39E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	57698001	rs12130571	C	A	rs12130571	21314694	8.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	58256148	rs12565523	T	G	rs12565523	24962325	4.04E-06	NA	1.3	[1.18-1.42]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	T	DAB1
1	58256191	rs12568292	C	A	rs12568292	24962325	4.04E-06	NA	1.3	[1.18-1.42]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	C	DAB1
1	58256544	rs35738462	T	C	rs35738462	24962325	2.00E-06	NA	1.32	[1.20-1.44]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs35738462-T	Research Support, N.I.H., Extramural	T	DAB1
1	58257250	rs1323838	T	C	rs1323838	24962325	2.41E-06	NA	1.32	[1.20-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	T	DAB1
1	58257587	rs7554147	T	C	rs7554147	24962325	2.41E-06	NA	1.32	[1.20-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	T	DAB1
1	58263767	rs7544843	G	A	rs7544843	24962325	3.53E-06	NA	1.32	[1.20-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	DAB1
1	59351143	rs17118349	C	T	rs17118349	20201924	8.07E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	59716043	rs12142820	A	T	rs12142820	21314694	5.10E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	62402549	rs10889272	C	T	rs10889272	21529783	1.00E-04	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	62890510	rs7523622	C	A	rs7523622	21314694	8.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	63384292	rs200589189	T	TG	rs7556152	21314694	1.43E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	63384292	rs7556152	T	G	rs7556152	21314694	1.43E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	66171970	rs12121677	T	C	rs12121677	20201924	5.57E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	66368865	rs17128103	C	T	rs17128103	21314694	4.34E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	66627732	rs2485381	G	A	rs2485381	24277619	8.44E-04	NA	0.38	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	PDE4B
1	67772582	rs3762317	A	G	rs3762317	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	68703087	rs12097456	C	T	rs12097456	24277619	9.88E-04	NA	0.61	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T,C	NA
1	69516639	rs2842040	G	A	rs2842040	24277619	9.79E-04	NA	0.38	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
1	69681190	rs12086324	C	T	rs12086324	24277619	1.04E-04	NA	0.64	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
1	70869116	rs664051	G	A	rs664051	24277619	2.94E-04	NA	0.76	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
1	70910065	rs12561944	A	G	rs12561944	20201924	4.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	70910065	rs12561944	A	G	rs12561944	20201924	8.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	70910065	rs12561944	A	G	rs12561944	pha002892	4.65E-05	phs000125	1.96	[1.41-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
1	70910065	rs12561944	A	G	rs12561944	pha002893	8.87E-05	phs000125	2.17	[1.47-3.23]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
1	71712223	rs12131265	C	T	rs12131265	23089632	1.34E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	71728900	rs11209757	T	G	rs11209757	23089632	1.29E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	74169283	rs9425128	C	T	rs9425128	20201924	6.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	74646058	rs17591292	C	T	rs17591292	21314694	5.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	76273313	rs5745331	A	G	rs5745331	20201924	3.47E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	76822600	rs12562911	A	G	rs12562911	21314694	7.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	81401098	rs10874182	C	T	rs10874182	24277619	4.92E-04	NA	0.59	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
1	83112722	rs373905	C	T	rs373905	21703634	2.06E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83117369	rs453456	G	A	rs453456	21703634	2.04E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83118044	rs2787985	T	G	rs2787985	21703634	1.20E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83132400	rs1433761	A	C	rs1433761	21703634	9.33E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83178180	rs1469743	G	T	rs1469743	21703634	5.92E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83184129	rs12744723	C	T	rs12744723	21703634	7.16E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83188821	rs10493727	C	T	rs10493727	21703634	4.51E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83196421	rs1338361	T	C	rs1338361	21703634	5.74E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83202936	rs11588508	A	G	rs11588508	21703634	5.61E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83203139	rs11588936	T	A	rs11588936	21703634	5.43E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	83231866	rs6429835	C	T	rs6429835	21703634	3.79E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	85240246	rs11576745	C	T	rs11576745	21314694	9.13E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	85898160	rs11161614	T	G	rs11161614	21314694	8.58E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	86085545	rs1999186	G	A	rs1999186	24277619	6.51E-04	NA	0.57	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
1	86465736	rs17128651	G	A	rs17128651	20201924	1.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	86465736	rs17128651	G	A	rs17128651	20201924	7.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	91141196	rs12116456	G	A	rs12116456	pha002893	8.28E-05	phs000125	1.95	[1.40-2.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
1	91155931	rs17131133	A	G	rs17131133	20201924	5.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	91155931	rs17131133	A	G	rs17131133	pha002893	5.10E-05	phs000125	2	[1.43-2.79]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
1	91175419	rs12133004	T	C	rs12133004	20201924	2.70E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	91175419	rs12133004	T	C	rs12133004	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	91175419	rs12133004	T	C	rs12133004	pha002893	2.75E-05	phs000125	2.05	[1.47-2.87]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
1	92332489	rs2489188	C	T	rs2489188	21314694	9.09E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	93939870	rs11164938	A	G	rs11164938	21314694	5.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	95249306	rs12743267	C	T	rs12743267	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	95302135	rs11165257	G	T	rs11165257	20201924	2.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	101199886	rs3176874	A	G	rs3176874	21703634	2.18E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	101620729	rs17417367	A	G	rs17417367	22096494	6.70E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
1	101784340	rs9433784	G	T	rs9433784	21314694	7.19E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	102312703	rs4907956	G	T	rs4907956	20202923	5.83E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	102312703	rs4907956	G	T	rs4907956	21703634	2.40E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	103348100	rs1241182	A	C	rs1241182	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	103348100	rs1241182	A	C	rs1241182	20201924	4.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	103763252	rs4907992	A	G	rs4907992	20201924	4.85E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	110652880	rs514341	C	T	rs514341	24962325	6.00E-06	NA	1.5	[1.32-1.68]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs514341-T	Research Support, N.I.H., Extramural	T	NA
1	110849205	rs17358933	G	A	rs17358933	21314694	8.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	111186784	rs2797533	C	T	rs2797533	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111206885	rs2640487	C	T	rs2640487	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111211533	rs1319782	C	T	rs1319782	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111213248	rs2640480	C	A	rs2640480	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111295050	rs41453452	G	C	rs41453452	21314694	3.09E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	111295674	rs420033	G	A	rs420033	19581569	6.17E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
1	111342490	rs343819	C	T	rs343819	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111342490	rs343819	C	T	rs343819	20201924	8.00E-06	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111342490	rs343819	C	T	rs343819	pha002893	7.98E-06	phs000125	1.69	[1.35-2.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
1	111393622	rs6685538	G	A	rs6685538	20201924	4.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111396088	rs4631693	C	T	rs4631693	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111396088	rs4631693	C	T	rs4631693	20201924	7.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111396088	rs4631693	C	T	rs4631693	pha002892	7.53E-05	phs000125	1.47	[1.20-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
1	111396606	rs718463	G	A	rs718463	20201924	2.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111396606	rs718463	G	A	rs718463	20201924	5.30E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111396606	rs718463	G	A	rs718463	pha002892	5.28E-05	phs000125	1.47	[1.22-1.79]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
1	111396915	rs12730405	A	G	rs12730405	20201924	2.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111396915	rs12730405	A	G	rs12730405	20201924	6.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111396915	rs12730405	A	G	rs12730405	pha002892	6.44E-05	phs000125	1.47	[1.22-1.79]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
1	111397090	rs6672672	C	T	rs6672672	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111397090	rs6672672	C	T	rs6672672	20201924	7.20E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111397090	rs6672672	C	T	rs6672672	pha002892	7.22E-05	phs000125	1.47	[1.22-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
1	111397176	rs6687919	T	G	rs6687919	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111397176	rs6687919	T	G	rs6687919	20201924	4.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111397316	rs6687898	A	G	rs6687898	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111397316	rs6687898	A	G	rs6687898	20201924	4.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111397451	rs6690536	T	C	rs6690536	20201924	1.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111397451	rs6690536	T	C	rs6690536	20201924	4.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111406899	rs6701134	A	G	rs6701134	20201924	2.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111406899	rs6701134	A	G	rs6701134	20201924	6.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111406899	rs6701134	A	G	rs6701134	pha002892	6.65E-05	phs000125	1.47	[1.22-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
1	111412912	rs7513168	T	C	rs7513168	20201924	1.50E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111412912	rs7513168	T	C	rs7513168	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111412912	rs7513168	T	C	rs7513168	pha002893	1.49E-05	phs000125	1.59	[1.30-1.96]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
1	111853581	rs4240530	C	T	rs4240530	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	111854207	rs4839122	T	C	rs4839122	21314694	5.05E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	113196896	rs3790598	G	A	rs3790598	20201924	1.91E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	115621860	rs17479252	C	T	rs17479252	21314694	9.95E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	115672145	rs11581510	G	A	rs11581510	20201924	5.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	115672145	rs11581510	G	A	rs11581510	20201924	8.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	115727948	rs195207	C	A	rs195207	21529783	8.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	115734091	rs195204	T	C	rs195204	21529783	9.00E-06	NA	0.1	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs195204-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	115839680	rs10489530	G	A	rs10489530	21314694	8.65E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	117754059	rs3806373	T	C	rs3806373	20201924	4.38E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	117759325	rs1892409	C	T	rs1892409	20201924	5.59E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	117759451	rs12098035	C	T	rs12098035	20201924	5.95E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	118864968	rs4375253	C	T	rs4375253	21703634	8.11E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	118878656	rs10802023	T	C	rs10802023	21703634	2.18E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	118903196	rs10923556	C	T	rs10923556	21703634	8.77E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	119512913	rs10923714	G	A	rs10923714	21314694	7.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	119795133	rs1341797	G	A	rs1341797	20201924	7.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	119795133	rs1341797	G	A	rs1341797	pha002892	6.95E-05	phs000125	1.47	[1.20-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
1	119854742	rs1891224	G	A	rs1891224	22096494	1.90E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
1	119871977	rs699771	C	A,G,T	rs699771	20202923	8.87E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	119871977	rs699771	C	A,G,T	rs699771	21956439	2.80E-05	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	119871977	rs699771	C	A,G,T	rs699771	22096494	1.70E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
1	145428296	rs6661602	C	T	rs6661602	21314694	2.76E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	145571398	rs6424380	T	C	rs6424380	21314694	1.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	147142457	rs13374159	C	T	rs13374159	20201924	6.26E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	152625148	rs10888505	A	G	rs10888505	20201924	8.56E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	152643160	rs12096806	G	A	rs12096806	20201924	3.22E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	152648950	rs12060809	T	C	rs12060809	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	153327756	rs12027903	G	T	rs12027903	20201924	4.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	154363985	rs11582424	A	C	rs11582424	24277619	6.04E-04	NA	0.49	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
1	154369252	rs17654071	A	G	rs17654071	24277619	3.53E-04	NA	0.44	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
1	154436195	rs4240872	C	T	rs4240872	20201924	4.51E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	155971887	rs11589188	T	C	rs11589188	21703634	6.00E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	156173082	rs2241109	C	T	rs2241109	20201924	6.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	156206121	rs1052067	G	A	rs1052067	20201924	5.12E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	156206121	rs1052067	G	A	rs1052067	pha002891	5.12E-05	phs000125	2.17	[1.49-3.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	PMF1	missense	NM_007221
1	157066129	rs1571045	C	T	rs1571045	20201924	1.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	157621513	rs2778010	T	C	rs2778010	21314694	3.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	157905143	rs12123554	T	C	rs12123554	20201924	5.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	157905143	rs12123554	T	C	rs12123554	pha002892	5.48E-05	phs000125	1.78	[1.34-2.35]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
1	158578865	rs12724903	A	C	rs12724903	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	161677807	rs1954174	C	T	rs1954174	21956439	5.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	162118046	rs1932933	T	C	rs1932933	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	162118046	rs1932933	T	C	rs1932933	23691058	0.00000582	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	162331621	rs6681981	A	G	rs6681981	20201924	5.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	162873220	rs12730805	C	A	rs12730805	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	164611901	rs10494419	T	G	rs10494419	21314694	2.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	167513418	rs1229430	C	T	rs1229430	21529783	8.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	169671088	rs964555	A	C	rs964555	20201924	2.34E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169671088	rs964555	A	C	rs964555	pha002891	2.34E-05	phs000125	2.22	[1.54-3.23]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	SELL	intron	NR_029467
1	169672343	rs4987314	C	T	rs4987314	20201924	1.23E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169672343	rs4987314	C	T	rs4987314	pha002891	1.23E-05	phs000125	2.27	[1.56-3.33]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SELL	intron	NR_029467
1	169673838	rs2229569	G	A	rs2229569	pha002891	9.88E-06	phs000125	2.22	[1.56-3.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	SELL	missense	NM_000655
1	169676223	rs2205847	G	T	rs2205847	20201924	1.94E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169677709	rs1051091	A	G	rs1051091	20201924	2.11E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169678024	rs4987285	T	C	rs4987285	20201924	6.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169678024	rs4987285	T	C	rs4987285	pha002891	6.00E-05	phs000125	1.96	[1.41-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SELL	intron	NM_000655
1	169681357	rs2205849	T	C	rs2205849	20201924	1.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169681357	rs2205849	T	C	rs2205849	pha002891	1.40E-05	phs000125	2.17	[1.54-3.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	SELL	nearGene-5	NM_000655
1	169688135	rs4656703	A	C	rs4656703	20201924	4.48E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169688135	rs4656703	A	C	rs4656703	pha002891	4.48E-05	phs000125	1.96	[1.43-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
1	169691219	rs3917449	G	A	rs3917449	20201924	5.35E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169691219	rs3917449	G	A	rs3917449	pha002891	5.35E-05	phs000125	1.89	[1.39-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
1	169692132	rs4786	T	C	rs4786	20201924	1.21E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169692522	rs5359	T	C	rs5359	20201924	6.98E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169692522	rs5359	T	C	rs5359	pha002891	6.98E-06	phs000125	1.11	[0.82-1.52]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SELE	UTR-3	NM_000450
1	169697444	rs1076637	C	T	rs1076637	20201924	1.89E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169697444	rs1076637	C	T	rs1076637	pha002891	1.89E-05	phs000125	2.08	[1.49-2.94]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	SELE	intron	NM_000450
1	169699819	rs3917419	G	A	rs3917419	20201924	2.43E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169699819	rs3917419	G	A	rs3917419	pha002891	2.43E-05	phs000125	2.15	[1.51-3.08]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	SELE	intron	NM_000450
1	169702705	rs932307	G	A	rs932307	20201924	3.96E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169702974	rs5353	T	C	rs5353	20201924	5.11E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	169702974	rs5353	T	C	rs5353	pha002891	5.11E-05	phs000125	1.05	[0.73-1.51]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	SELE	intron	NM_000450
1	170172417	rs10158534	T	G	rs10158534	20201924	4.61E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	170208724	rs1412787	C	T	rs1412787	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	171079700	rs7051320	C	T	rs7051320	21314694	4.98E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	172368967	rs6698987	T	C	rs6698987	21314694	1.76E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	172624864	rs2859242	C	T	rs2859242	20201924	6.73E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	172624864	rs2859242	C	T	rs2859242	pha002891	6.73E-05	phs000125	1.85	[1.37-2.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
1	173235835	rs844656	T	G	rs844656	21529783	7.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	174923346	rs3753563	T	C	rs3753563	21529783	7.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	175094025	rs12094153	G	A	rs12094153	21703634	5.49E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	175107826	rs2157588	C	T	rs2157588	21703634	7.16E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	175120079	rs6701037	A	C	rs6701037	20202923	1.75E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175120079	rs6701037	A	C	rs6701037	21703634	2.00E-07	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs6701037-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	175120079	rs6701037	A	C	rs6701037	21956439	2.30E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175125036	rs6425323	C	T	rs6425323	20202923	2.27E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175125036	rs6425323	C	T	rs6425323	21703634	3.13E-07	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	175125036	rs6425323	C	T	rs6425323	21956439	2.80E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175126423	rs1057302	A	G	rs1057302	20202923	1.94E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175126423	rs1057302	A	G	rs1057302	21703634	5.12E-07	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	175126423	rs1057302	A	G	rs1057302	21956439	6.20E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175128711	rs4650716	C	A	rs4650716	21703634	2.57E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	175130204	rs1057239	G	A	rs1057239	20202923	2.01E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175130204	rs1057239	G	A	rs1057239	21703634	1.93E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	175130204	rs1057239	G	A	rs1057239	21956439	3.10E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175132371	rs1894709	G	T	rs1894709	20202923	2.78E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175132371	rs1894709	G	T	rs1894709	21703634	2.12E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	175132371	rs1894709	G	T	rs1894709	21956439	4.30E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	175134677	rs10489326	A	G	rs10489326	21703634	4.90E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	176975445	rs12135256	C	G	rs12135256	21314694	9.76E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	178517591	rs4233175	A	G	rs4233175	20202923	3.78E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	178518008	rs10913569	A	G	rs10913569	20202923	9.22E-07	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	179516072	rs1410587	C	T	rs1410587	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	179521932	rs2274626	G	T	rs2274626	20201924	7.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	179609589	rs16854429	G	T	rs16854429	21703634	7.29E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	180774130	rs3789373	C	T	rs3789373	21314694	9.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	182116368	rs12564594	A	G	rs12564594	20201924	3.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	183190451	rs16860582	T	C	rs16860582	20201924	2.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	184493884	rs2001270	A	G	rs2001270	21529783	1.00E-04	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	186692562	rs2205953	T	C	rs2205953	21314694	7.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	186961326	rs761516	T	G	rs761516	21314694	5.15E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	187422872	rs1938512	C	A	rs1938512	24277619	3.45E-04	NA	0.44	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
1	191340943	rs6690512	G	A	rs6690512	24277619	7.68E-04	NA	0.88	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G,A	NA
1	196061711	rs11579497	G	A	rs11579497	19581569	2.60E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
1	196089818	rs12036795	A	C	rs12036795	19581569	3.94E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
1	197844367	rs10801629	C	T	rs10801629	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	197844367	rs10801629	C	T	rs10801629	23691058	0.00000413	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	197862321	rs10922323	T	C	rs10922323	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	197862321	rs10922323	T	C	rs10922323	23691058	0.00000646	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	201328824	rs2275863	G	A	rs2275863	21529783	7.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	201347315	rs2799686	A	G	rs2799686	21529783	1.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	204392257	rs4951373	G	A	rs4951373	20201924	1.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	204392257	rs4951373	G	A	rs4951373	20201924	6.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	204392257	rs4951373	G	A	rs4951373	pha002892	6.42E-05	phs000125	1.72	[1.33-2.27]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	PIK3C2B	UTR-3	NM_002646
1	204426373	rs2137255	C	T	rs2137255	21314694	4.57E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	204614475	rs11801229	A	G	rs11801229	21314694	5.28E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	205554095	rs7515820	A	C	rs7515820	21314694	8.95E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	206915334	rs4845133	C	G	rs4845133	21314694	9.11E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	207252911	rs12088135	C	T	rs12088135	21314694	6.19E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	208914856	rs4844438	A	G	rs4844438	24277619	9.20E-04	NA	0.5	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
1	209203866	rs12030256	T	C	rs12030256	20201924	2.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	211126407	rs1501558	G	A	rs1501558	20201924	3.06E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	211176922	rs1501551	C	T	rs1501551	20201924	6.18E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	211493573	rs6540681	A	G	rs6540681	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	212602176	rs612414	G	T	rs612414	23089632	0.000010661	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	212610755	rs583058	T	C	rs583058	23089632	0.0000142	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	212619339	rs4804	T	C	rs4804	23089632	0.000715	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	212619339	rs4804	T	C	rs4804	23089632	8.36E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	212620214	rs483954	A	G	rs483954	23089632	0.0000039	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	212620214	rs483954	A	G	rs483954	23089632	0.00063	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	212634583	rs675065	A	G	rs675065	24277619	4.26E-04	NA	0.42	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
1	213779196	rs11120170	G	A	rs11120170	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	214261350	rs1440620	T	C	rs1440620	24277619	9.98E-04	NA	0.41	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
1	214416824	rs6665548	A	G	rs6665548	21314694	6.04E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	215102422	rs7534785	G	A	rs7534785	21314694	5.29E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	215649097	rs1911546	C	T	rs1911546	21314694	3.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	215825167	rs2677112	T	G	rs2677112	21314694	8.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	215839090	rs11120594	G	A	rs11120594	21529783	1.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	217094044	rs11572505	T	C	rs11572505	20201924	1.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	219083060	rs9661984	T	G	rs9661984	24277619	7.42E-04	NA	0.38	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
1	220931227	rs6659246	C	A	rs6659246	20201924	2.37E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	220935808	rs10779415	C	T	rs10779415	20201924	8.31E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	220935977	rs3795536	G	A	rs3795536	20201924	6.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	220936568	rs11118597	G	A	rs11118597	20201924	4.46E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	220984364	rs11118607	C	T	rs11118607	21314694	2.85E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	222751791	rs2936032	C	T	rs2936032	22096494	5.40E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
1	223349020	rs851171	G	A	rs851171	21314694	5.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	226820500	rs1050492	G	A	rs1050492	21314694	8.29E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	228543303	rs11578798	T	A	rs11578798	21314694	8.75E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	229105145	rs603404	A	G	rs603404	20201924	7.80E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	229105145	rs603404	A	G	rs603404	20201924	9.00E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	229105145	rs603404	A	G	rs603404	pha002892	7.84E-05	phs000125	1.43	[1.20-1.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
1	229105145	rs603404	A	G	rs603404	pha002893	9.02E-05	phs000125	1.04	[0.66-1.64]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
1	231658301	rs1059595	A	G	rs1059595	21314694	7.14E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	232811429	rs6699751	T	C	rs6699751	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	233098875	rs4141442	T	C	rs4141442	20201924	7.55E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	233100404	rs7523847	C	A	rs7523847	20201924	6.14E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	234230388	rs2045518	A	G	rs2045518	21314694	9.20E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	235094931	rs2802928	A	G	rs2802928	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	235290922	rs4329572	C	A	rs4329572	21529783	1.00E-04	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	237945870	rs12737847	T	C	rs12737847	20201924	4.39E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	238771226	rs7517092	T	C	rs7517092	20201924	1.59E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	238818794	rs16837283	T	C	rs16837283	24277619	9.69E-04	NA	0.48	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
1	239743257	rs12135445	G	A	rs12135445	24277619	4.71E-04	NA	0.6	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
1	239778660	rs12080951	C	T	rs12080951	24277619	2.64E-04	NA	1	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
1	240564513	rs10802867	A	G	rs10802867	20201924	2.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	240599099	rs10926254	A	G	rs10926254	20201924	6.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	241264216	rs12086317	A	G	rs12086317	24277619	8.53E-04	NA	1.79	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	RGS7
1	241288510	rs10158567	G	A	rs10158567	21314694	7.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	241684831	rs6678986	A	G	rs6678986	24277619	9.33E-04	NA	0.83	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	FH
1	241868349	rs9428890	G	A	rs9428890	21314694	2.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
1	244314476	rs913992	C	T	rs913992	20201924	1.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	244314476	rs913992	C	T	rs913992	20201924	4.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
1	247348189	rs3738443	C	T	rs3738443	21314694	4.00E-06	AA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs3738443-A	Research Support, N.I.H., Extramural
2	355800	rs6740249	T	C	rs6740249	21314694	4.37E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	1076684	rs4971371	C	T	rs4971371	21314694	5.57E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	2848102	rs823243	T	C	rs823243	20201924	8.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	4517511	rs648196	G	T	rs648196	20201924	3.06E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	4592241	rs1670530	C	T	rs1670530	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	6522333	rs6739653	G	A	rs6739653	20201924	7.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	6529504	rs1564032	T	C	rs1564032	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	6551857	rs6723180	A	G	rs6723180	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	6551873	rs6726264	T	C	rs6726264	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	9676413	rs17362650	T	C	rs17362650	24962325	8.00E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs17362650-C	Research Support, N.I.H., Extramural	T	ADAM17
2	10667749	rs2540275	G	A	rs2540275	20201924	1.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	11748406	rs12476319	T	C	rs12476319	21314694	5.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	11767282	rs7562399	G	A	rs7562399	20201924	7.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	12132638	rs1036668	G	T	rs1036668	24277619	9.71E-04	NA	0.47	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
2	12778345	rs6432321	T	C	rs6432321	24277619	2.25E-04	NA	0.67	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
2	16131782	rs6706117	A	G	rs6706117	20201924	5.34E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	18860375	rs1550771	T	C	rs1550771	20201924	5.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	19184996	rs884895	G	A	rs884895	21529783	7.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
2	26677303	rs2280515	G	T	rs2280515	21314694	2.68E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	29747174	rs12467802	C	T	rs12467802	21703634	7.40E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	29767894	rs7592571	C	A	rs7592571	21703634	8.53E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	29785679	rs10193521	G	A	rs10193521	21703634	5.27E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	29785781	rs12473275	G	A	rs12473275	21703634	6.11E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	30699970	rs829642	T	C	rs829642	20201924	4.80E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	30699970	rs829642	T	C	rs829642	pha002892	4.80E-05	phs000125	1.54	[1.25-1.89]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	LCLAT1	intron	NM_001002257
2	30719326	rs829646	T	C	rs829646	20201924	6.30E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	30719326	rs829646	T	C	rs829646	pha002892	6.34E-05	phs000125	1.52	[1.23-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	LCLAT1	intron	NM_001002257
2	30776270	rs4952147	G	A	rs4952147	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	30871808	rs2609954	G	A	rs2609954	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	32933095	rs6743661	T	G	rs6743661	20201924	1.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	35224451	rs17387182	C	T	rs17387182	20201924	7.75E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	35235120	rs17398711	C	T	rs17398711	20201924	7.54E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	35235120	rs17398711	C	T	rs17398711	pha002891	7.54E-05	phs000125	2.31	[1.52-3.49]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
2	36163832	rs2968625	A	G	rs2968625	20201924	4.03E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	36169533	rs2949081	G	T	rs2949081	20201924	4.03E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	36571139	rs10490672	A	C	rs10490672	21314694	6.14E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	37412935	rs11895771	T	G	rs11895771	21314694	3.95E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	38682719	rs12997019	T	C	rs12997019	21314694	3.40E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	40096398	rs7566309	A	G	rs7566309	24277619	6.00E-04	NA	0.63	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
2	40634834	rs9789765	A	T	rs9789765	21314694	4.58E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	41486554	rs17027360	A	G	rs17027360	20201924	3.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	41505473	rs1441231	T	C	rs1441231	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	42350487	rs6733455	C	T	rs6733455	21314694	7.08E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	44443079	rs2053458	C	G	rs2053458	21314694	9.57E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	44620810	rs1067344	T	G	rs1067344	21314694	3.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	45312967	rs2959236	T	C	rs2959236	20201924	5.47E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	45574206	rs4245803	G	A	rs4245803	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	45635465	rs2216506	T	C	rs2216506	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	45855315	rs12622230	A	C	rs12622230	20201924	4.02E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	45855315	rs12622230	A	C	rs12622230	pha002891	4.02E-05	phs000125	2.33	[1.56-3.57]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
2	47819972	rs4245815	G	A	rs4245815	20201924	6.62E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	49158325	rs989373	T	C	rs989373	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	51247294	rs13382584	T	C	rs13382584	20201924	7.12E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	55103265	rs13385982	G	T	rs13385982	20201924	2.07E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	55111689	rs2163618	G	A	rs2163618	20201924	3.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	56140531	rs2033316	A	G	rs2033316	21529783	7.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	56228351	rs13029542	C	T	rs13029542	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	56244096	rs4553860	A	G	rs4553860	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	56246340	rs1347093	G	T	rs1347093	20201924	4.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	56563822	rs9808416	C	T	rs9808416	21529783	2.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
2	56600669	rs17047859	A	C	rs17047859	21314694	1.55E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	56609371	rs17047868	G	A	rs17047868	22096494	6.00E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
2	58522661	rs11885675	T	A	rs11885675	21314694	9.48E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	59072969	rs17552189	C	T	rs17552189	20201924	8.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	59072969	rs17552189	C	T	rs17552189	pha002892	8.46E-05	phs000125	1.43	[1.20-1.71]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	FLJ30838	intron	NR_033873
2	59979504	rs17050411	T	C	rs17050411	24277619	9.96E-04	NA	0.48	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
2	59987774	rs11125811	T	C	rs11125811	24277619	7.02E-04	NA	0.59	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
2	62432133	rs7605321	G	A	rs7605321	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	64105553	rs12993544	A	G	rs12993544	20201924	6.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	64553440	rs919123	A	C	rs919123	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	64553440	rs919123	A	C	rs919123	20201924	4.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	68204413	rs17034763	C	T	rs17034763	24277619	3.77E-04	NA	0.41	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
2	72725947	rs11126370	G	A	rs11126370	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	72735509	rs2138683	G	A	rs2138683	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	72789317	rs12471136	A	G	rs12471136	20201924	8.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	72795730	rs1446890	G	A	rs1446890	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	75449983	rs1468900	A	G	rs1468900	20201924	1.32E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	78304795	rs11126651	T	G	rs11126651	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	78304795	rs11126651	T	G	rs11126651	20201924	8.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	78305622	rs7573381	A	G	rs7573381	20201924	6.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	80770808	rs13423141	C	T	rs13423141	20201924	8.74E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	80770808	rs13423141	C	T	rs13423141	pha002891	8.74E-05	phs000125	1.85	[1.37-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	CTNNA2	intron	NM_004389
2	80771190	rs7605261	T	G	rs7605261	20201924	5.73E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	82892794	rs6731289	C	A	rs6731289	21529783	7.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	84057963	rs4832336	G	A	rs4832336	20201924	5.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	84815684	rs17759625	A	G	rs17759625	21314694	6.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	88395824	rs2970911	G	A	rs2970911	21314694	7.03E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	95629038	rs10172167	T	G	rs10172167	21314694	3.22E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	100275925	rs11676683	A	C	rs11676683	24277619	5.80E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	AFF3
2	100288931	rs4851222	G	A	rs4851222	24277619	5.80E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	AFF3
2	101699063	rs7608232	C	A	rs7608232	21314694	6.09E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	103296936	rs6726894	C	G	rs6726894	21314694	1.01E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	105158776	rs17029932	G	A	rs17029932	21703634	9.91E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	106714038	rs10206195	T	C	rs10206195	21314694	9.10E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	112425540	rs1399665	A	G	rs1399665	24277619	6.66E-04	NA	0.41	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
2	113553426	rs6746923	A	G	rs6746923	21529783	1.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	113627234	rs2708914	T	G	rs2708914	20201924	4.47E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	113639584	rs17042517	A	G	rs17042517	21314694	3.34E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	113948159	rs6753019	G	A	rs6753019	24277619	5.89E-04	NA	0.47	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	PSD4
2	114083363	rs1191695	T	C	rs1191695	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	118716190	rs4142224	C	T	rs4142224	21314694	1.83E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	119000652	rs10864971	C	T	rs10864971	21529783	8.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T,C
2	119942886	rs11123504	G	A	rs11123504	21314694	1.46E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	119957026	rs4849770	G	A	rs4849770	21314694	1.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	121004979	rs3980213	A	G	rs3980213	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	121014589	rs1370379	C	T	rs1370379	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	121041347	rs3931840	A	C	rs3931840	20201924	6.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	122847139	rs1922179	C	T	rs1922179	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	127357688	rs7590496	C	A	rs7590496	20201924	3.93E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	127821207	rs1137845	G	A	rs1137845	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	129819469	rs11682667	T	C	rs11682667	23089632	7.06E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	129982956	rs13033188	C	T	rs13033188	24962325	8.33E-06	NA	1.27	[1.17-1.36]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
2	129983014	rs1251209	A	G	rs1251209	24962325	6.50E-06	NA	1.28	[1.18-1.38]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
2	129983131	rs2119515	G	A	rs2119515	24962325	9.42E-06	NA	1.28	[1.18-1.38]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2119515-G	Research Support, N.I.H., Extramural	G	NA
2	129983541	rs1251210	G	A	rs1251210	24962325	9.42E-06	NA	1.28	[1.18-1.38]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1251210-G	Research Support, N.I.H., Extramural	G	NA
2	129983664	rs1270481	T	C	rs1270481	24962325	5.12E-06	NA	1.28	[1.18-1.38]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1270481-T	Research Support, N.I.H., Extramural	T	NA
2	129984402	rs735987	G	A	rs735987	24962325	1.22E-06	NA	1.29	[1.19-1.39]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs735987-G	Research Support, N.I.H., Extramural	G	NA
2	129985114	rs1251214	C	A	rs1251214	24962325	9.24E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1251214-C	Research Support, N.I.H., Extramural	C	NA
2	129985154	rs1251215	C	T	rs1251215	24962325	9.24E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1251215-C	Research Support, N.I.H., Extramural	G	NA
2	129985182	rs1268546	T	C	rs1268546	24962325	9.24E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1268546-T	Research Support, N.I.H., Extramural	A	NA
2	129985210	rs1251216	G	C	rs1251216	24962325	9.24E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1251216-G	Research Support, N.I.H., Extramural	G	NA
2	129985425	rs2406641	A	G	rs2406641	24962325	9.24E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2406641-A	Research Support, N.I.H., Extramural	A	NA
2	129987520	rs1251205	T	A	rs1251205	24962325	9.24E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1251205-T	Research Support, N.I.H., Extramural	T	NA
2	129989847	rs12472824	C	T	rs12472824	24962325	8.18E-06	NA	1.28	[1.16-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs12472824-T	Research Support, N.I.H., Extramural	C	NA
2	129990197	rs4662907	G	A	rs4662907	24962325	5.69E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs4662907-A	Research Support, N.I.H., Extramural	G	NA
2	129990869	rs13033217	T	C	rs13033217	24962325	5.69E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs13033217-C	Research Support, N.I.H., Extramural	T	NA
2	129991012	rs1078826	G	A	rs1078826	24962325	5.69E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1078826-A	Research Support, N.I.H., Extramural	G	NA
2	129994332	rs1660895	A	T	rs1660895	24962325	7.00E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1660895-A	Research Support, N.I.H., Extramural	A	NA
2	129995501	rs35878075	G	A	rs35878075	24962325	6.78E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs35878075-A	Research Support, N.I.H., Extramural	G	NA
2	129996746	rs879533	T	A	rs879533	24962325	7.46E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs879533-T	Research Support, N.I.H., Extramural	A	NA
2	129996988	rs1734330	A	T	rs1734330	24962325	7.46E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1734330-A	Research Support, N.I.H., Extramural	T	NA
2	129997083	rs3856372	T	A	rs3856372	24962325	6.04E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs3856372-A	Research Support, N.I.H., Extramural	A	NA
2	129997543	rs894110	C	G	rs894110	24962325	7.64E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs894110-C	Research Support, N.I.H., Extramural	C	NA
2	129998033	rs935085	T	C	rs935085	24962325	7.64E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs935085-T	Research Support, N.I.H., Extramural	T	NA
2	129998443	rs2952621	T	C	rs2952621	23089632	9.51E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	129998443	rs2952621	T	C	rs2952621	24962325	7.64E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2952621-T	Research Support, N.I.H., Extramural	C	NA
2	129999190	rs1251172	G	A	rs1251172	24962325	7.64E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1251172-G	Research Support, N.I.H., Extramural	A	NA
2	129999796	rs4662640	A	C	rs4662640	24962325	6.77E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs4662640-C	Research Support, N.I.H., Extramural	A	NA
2	130000272	rs4662641	G	A	rs4662641	24962325	6.77E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs4662641-A	Research Support, N.I.H., Extramural	G	NA
2	130001725	rs10167178	C	T	rs10167178	24962325	6.77E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10167178-T	Research Support, N.I.H., Extramural	C	NA
2	130002073	rs1441141	A	G	rs1441141	24962325	6.77E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1441141-G	Research Support, N.I.H., Extramural	A	NA
2	130002186	rs6708498	C	T	rs6708498	24962325	5.97E-06	NA	1.28	[1.18-1.38]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6708498-C	Research Support, N.I.H., Extramural	C	NA
2	130003278	rs1441142	G	A	rs1441142	24962325	6.77E-06	NA	1.29	[1.17-1.41]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1441142-A	Research Support, N.I.H., Extramural	G	NA
2	130003735	rs1251179	A	G	rs1251179	24962325	1.25E-06	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1251179-A	Research Support, N.I.H., Extramural	A	NA
2	130004151	rs837827	G	A	rs837827	24962325	9.77E-07	NA	1.3	[1.20-1.40]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs837827-G	Research Support, N.I.H., Extramural	A	NA
2	130007175	rs6756671	G	A	rs6756671	24962325	9.70E-06	NA	1.27	[1.17-1.37]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6756671-G	Research Support, N.I.H., Extramural	G	NA
2	130550135	rs2464786	G	A	rs2464786	21703634	2.59E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	130562942	rs2707653	C	T	rs2707653	21703634	6.09E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	131537733	rs272146	C	A	rs272146	24277619	7.73E-04	NA	0.39	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
2	136817616	rs2011946	C	A	rs2011946	20202923	4.15E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	136817616	rs2011946	C	A	rs2011946	21703634	6.73E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	137009006	rs4477975	A	G	rs4477975	21703634	9.68E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	137194436	rs16834223	A	G	rs16834223	21529783	4.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	137207082	rs10496746	C	T	rs10496746	21529783	2.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
2	137240304	rs2033172	A	G	rs2033172	21529783	6.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	138227442	rs1869324	G	A	rs1869324	20201924	5.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	138227442	rs1869324	G	A	rs1869324	21703634	4.71E-07	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	138249452	rs2375511	C	A	rs2375511	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	139671955	rs9636231	G	A	rs9636231	21956439	8.00E-06	EA + AA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	139710863	rs10803574	G	A	rs10803574	21703634	9.52E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	139710863	rs10803574	G	A	rs10803574	21956439	1.80E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	139758906	rs3922799	G	A	rs3922799	21703634	6.48E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	139778282	rs1505846	C	T	rs1505846	21703634	9.39E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	139778282	rs1505846	C	T	rs1505846	21956439	2.00E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	139804141	rs1605136	A	G	rs1605136	21703634	7.51E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	139808906	rs11688290	C	T	rs11688290	21703634	3.18E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	141977173	rs7558514	G	A	rs7558514	21314694	1.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	142530120	rs10928122	G	T	rs10928122	20201924	6.63E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	143890281	rs16858596	G	A	rs16858596	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	146382236	rs2381750	G	T	rs2381750	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	146997640	rs11692798	C	T	rs11692798	24277619	5.08E-04	NA	0.4	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
2	149875961	rs7577450	A	G	rs7577450	pha002893	8.32E-05	phs000125	1.53	[1.24-1.90]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
2	149892614	rs10929935	T	C	rs10929935	20201924	6.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	149892614	rs10929935	T	C	rs10929935	20201924	7.30E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	149892614	rs10929935	T	C	rs10929935	pha002893	7.26E-05	phs000125	1.54	[1.25-1.92]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
2	149894724	rs16822509	T	C	rs16822509	20201924	3.20E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	149894724	rs16822509	T	C	rs16822509	pha002893	3.22E-05	phs000125	1.56	[1.27-1.93]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
2	149905641	rs10201643	T	G	rs10201643	20201924	2.00E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	149905641	rs10201643	T	G	rs10201643	pha002893	1.96E-05	phs000125	1.58	[1.28-1.94]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	LYPD6B	intron	NM_177964
2	150948703	rs330630	T	C	rs330630	21956439	3.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	151126403	rs6716455	G	A	rs6716455	21529783	7.00E-07	NA	0.12	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol use disorder factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D019973	Alcohol-Related Disorders	NA	NA	Drug abuse	rs6716455-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	151126403	rs6716455	G	A	rs6716455	21529783	9.00E-06	NA	0.11	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol dependence factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs6716455-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	152633114	rs12472627	C	T	rs12472627	21314694	4.82E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	154272542	rs13418009	A	G	rs13418009	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	159141224	rs2602189	A	C	rs2602189	20201924	2.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	159141224	rs2602189	A	C	rs2602189	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	159458601	rs17421757	G	A	rs17421757	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161386729	rs13382644	G	A	rs13382644	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161395188	rs6432628	C	T	rs6432628	20201924	9.10E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161395188	rs6432628	C	T	rs6432628	pha002892	9.13E-05	phs000125	1.49	[1.22-1.82]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
2	161406793	rs7598938	C	T	rs7598938	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161409559	rs13034284	C	T	rs13034284	20201924	1.80E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161409559	rs13034284	C	T	rs13034284	pha002892	1.85E-05	phs000125	1.52	[1.25-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
2	161410542	rs13410476	G	A	rs13410476	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161420179	rs9967749	A	G	rs9967749	20201924	8.10E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161420179	rs9967749	A	G	rs9967749	pha002892	8.13E-05	phs000125	1.47	[1.22-1.79]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
2	161424684	rs11681327	A	G	rs11681327	20201924	4.80E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161424684	rs11681327	A	G	rs11681327	pha002892	4.77E-05	phs000125	1.49	[1.23-1.79]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
2	161431604	rs7603576	A	G	rs7603576	20201924	4.70E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	161431604	rs7603576	A	G	rs7603576	pha002892	4.65E-05	phs000125	1.49	[1.23-1.82]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
2	161608769	rs17220405	C	T	rs17220405	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	162820220	rs16846221	G	T	rs16846221	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	162885450	rs2268888	C	T	rs2268888	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	165956508	rs3816195	T	G	rs3816195	24277619	5.29E-04	NA	0.5	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	SCN3A
2	165961865	rs1347992	T	C	rs1347992	24277619	4.85E-04	NA	0.5	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	SCN3A
2	166067658	rs2028891	T	G	rs2028891	24277619	1.40E-04	NA	0.47	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
2	168408438	rs1897339	T	G	rs1897339	20201924	3.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	170675765	rs3769769	C	T	rs3769769	21529783	9.80E-06	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	170954406	rs1381471	T	C	rs1381471	21529783	3.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	171695070	rs3791853	A	G	rs3791853	21314694	2.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	172006576	rs16859177	C	T	rs16859177	21314694	4.04E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	172946315	rs788160	T	G	rs788160	21529783	5.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	174125960	rs6761224	T	C	rs6761224	20201924	6.99E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	174852785	rs10497422	G	T	rs10497422	19581569	1.58E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	177070756	rs1026028	C	A	rs1026028	23089632	3.41E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	177071181	rs2166512	T	C	rs2166512	23089632	4.89E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	177962141	rs4894243	C	T	rs4894243	19581569	7.46E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	178890329	rs2117740	A	G	rs2117740	24962325	6.43E-06	NA	1.32	[1.20-1.44]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2117740-G	Research Support, N.I.H., Extramural	A	PDE11A
2	182906711	rs16822370	G	T	rs16822370	21314694	5.55E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	184407963	rs2368446	T	C	rs2368446	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	190402222	rs17271148	G	A	rs17271148	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	190425474	rs11539983	T	C	rs11539983	20201924	5.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	190432613	rs10188230	T	C	rs10188230	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	190771945	rs62184315	T	C	rs62184315	24962325	4.00E-06	NA	1.47	[1.31-1.63]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs62184315-T	Research Support, N.I.H., Extramural	T	NA
2	190779803	rs7563391	G	C	rs7563391	24962325	3.81E-06	NA	1.47	[1.31-1.63]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
2	190781764	rs62184317	C	T	rs62184317	24962325	3.81E-06	NA	1.47	[1.31-1.63]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
2	192532017	rs4592792	A	G	rs4592792	24277619	7.53E-04	NA	0.62	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
2	196505964	rs10460389	C	A	rs10460389	21314694	4.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	196517509	rs11682521	G	A	rs11682521	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	196536150	rs7424415	T	C	rs7424415	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	196536505	rs1866452	A	G	rs1866452	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	196542002	rs10178320	T	C	rs10178320	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	196549436	rs1561451	A	G	rs1561451	20201924	8.90E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	196549436	rs1561451	A	G	rs1561451	pha002892	8.86E-05	phs000125	1.46	[1.21-1.76]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SLC39A10	intron	NM_020342
2	196565241	rs6706771	G	T	rs6706771	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	196587670	rs6756374	C	A	rs6756374	20201924	1.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	196665083	rs6434799	C	T	rs6434799	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	196676489	rs6743998	T	C	rs6743998	21314694	7.57E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	197522966	rs10197202	G	A	rs10197202	21529783	1.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	198164530	rs1896857	A	G	rs1896857	24962325	8.00E-06	NA	1.3	[1.18-1.42]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1896857-A	Research Support, N.I.H., Extramural	C	ANKRD44
2	198982858	rs10180112	C	G	rs10180112	21314694	5.22E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	201525920	rs3815502	C	G	rs3815502	21314694	1.97E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	201527239	rs2241080	G	A	rs2241080	21314694	3.95E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	201576284	rs7563911	A	C,G,T	rs7563911	21529783	6.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	202196063	rs9288318	C	A	rs9288318	20201924	6.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	202241907	rs10202963	T	G	rs10202963	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	202928940	rs7566288	G	T	rs7566288	21529783	8.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	203469588	rs13432396	C	A	rs13432396	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203583254	rs7571219	G	A	rs7571219	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203602207	rs7602496	C	A	rs7602496	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203606754	rs7581854	T	C	rs7581854	20201924	4.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203606754	rs7581854	T	C	rs7581854	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203608742	rs6435163	T	C	rs6435163	20201924	4.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203608742	rs6435163	T	C	rs6435163	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203627311	rs2351116	G	A	rs2351116	20201924	4.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203627311	rs2351116	G	A	rs2351116	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203627412	rs2351117	C	T	rs2351117	20201924	5.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203628757	rs11685819	G	A	rs11685819	20201924	4.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	203628757	rs11685819	G	A	rs11685819	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	204051009	rs10182274	G	A	rs10182274	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	204051009	rs10182274	G	A	rs10182274	20201924	9.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	204051009	rs10182274	G	A	rs10182274	pha002893	9.90E-05	phs000125	1.54	[1.24-1.91]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NBEAL1	intron	NM_001114132
2	204060148	rs2117266	G	T	rs2117266	20201924	1.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	204459179	rs17478537	T	C	rs17478537	21314694	7.55E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	206025174	rs849118	G	A	rs849118	21314694	5.32E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	212416029	rs13421680	A	G	rs13421680	21314694	4.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	212431529	rs11885579	A	G	rs11885579	21314694	9.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	213611221	rs16849209	G	T	rs16849209	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	214592382	rs7597928	A	G	rs7597928	21314694	1.44E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	215350167	rs13425618	A	G	rs13425618	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	215356938	rs4629153	C	T	rs4629153	20201924	3.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	215356938	rs4629153	C	T	rs4629153	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	215370052	rs9288497	A	G	rs9288497	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	215370052	rs9288497	A	G	rs9288497	20201924	5.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	215833415	rs4673925	A	G	rs4673925	20201924	3.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	215833622	rs6756540	G	T	rs6756540	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	215834466	rs1464678	A	G	rs1464678	20201924	2.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	215834676	rs3795857	A	G	rs3795857	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	216893637	rs1344694	T	G	rs1344694	19581569	1.47E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
2	216893637	rs1344694	T	G	rs1344694	22004471	5.00E-06	NA	1.27	[1.15-1.41]	1,333 European ancestry cases; 2,168 European ancestry controls	European(3501)	ALL(3501)	EUR(3501)	ALL(3501)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	216898658	rs7590720	G	A	rs7590720	19581569	1.00E-08	NA	1.35	[1.22-1.49]	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs7590720-G	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	216933792	rs705648	C	T	rs705648	19581569	6.17E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
2	217640818	rs7421283	C	T	rs7421283	21314694	2.90E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	218862241	rs1001098	C	T	rs1001098	20201924	7.33E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	226456461	rs1993323	C	A	rs1993323	20201924	2.89E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	226515698	rs7595617	A	G	rs7595617	20201924	8.17E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	227131780	rs964818	C	A	rs964818	20201924	2.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	227131780	rs964818	C	A	rs964818	20201924	4.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	227131780	rs964818	C	A	rs964818	pha002893	4.37E-05	phs000125	1.82	[1.37-2.44]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
2	227148722	rs4510219	A	C	rs4510219	20201924	2.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	227148722	rs4510219	A	C	rs4510219	20201924	4.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	227148722	rs4510219	A	C	rs4510219	pha002893	4.86E-05	phs000125	1.82	[1.35-2.38]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
2	227174909	rs3914465	A	G	rs3914465	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	227174909	rs3914465	A	G	rs3914465	20201924	1.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	227174909	rs3914465	A	G	rs3914465	pha002893	1.85E-05	phs000125	1.89	[1.41-2.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
2	230545356	rs2216249	T	C	rs2216249	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231009554	rs1365773	C	A	rs1365773	20201924	7.57E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231230171	rs6712333	C	T	rs6712333	23942779	6.10E-05	NA	0.45	[NA] unit increase	7,188 European ancestry individuals	European(7188)	ALL(7188)	EUR(7188)	ALL(7188)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs6712333-A	Twin Study	Research Support, N.I.H., Extramural	C
2	231573384	rs9973480	A	C	rs9973480	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231573384	rs9973480	A	C	rs9973480	20201924	5.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231574896	rs11682404	A	G	rs11682404	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231574896	rs11682404	A	G	rs11682404	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231582196	rs10933355	G	A	rs10933355	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231582196	rs10933355	G	A	rs10933355	20201924	3.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231586340	rs13411251	T	G	rs13411251	20201924	2.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231586340	rs13411251	T	G	rs13411251	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231594089	rs6711453	A	G	rs6711453	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231594089	rs6711453	A	G	rs6711453	20201924	3.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231613141	rs6717266	G	A	rs6717266	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231613141	rs6717266	G	A	rs6717266	20201924	3.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231673225	rs3792068	A	G	rs3792068	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	231673225	rs3792068	A	G	rs3792068	20201924	4.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	236795801	rs11688841	G	A	rs11688841	21314694	9.89E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	237429154	rs7607774	G	A	rs7607774	21956439	4.00E-07	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
2	237509207	rs896543	G	A	rs896543	23089632	0.00000435	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	237509207	rs896543	G	A	rs896543	23089632	4.75E-07	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	237509207	rs896543	G	A	rs896543	24962325	1.00E-06	NA	1.54	[1.36-1.72]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs896543-G	Research Support, N.I.H., Extramural	A	NA
2	237516294	rs7565777	A	G	rs7565777	24962325	3.60E-06	NA	1.49	[1.32-1.67]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
2	237517937	rs6431476	T	C	rs6431476	23089632	0.00000114	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	237517937	rs6431476	T	C	rs6431476	23089632	0.00000392	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	237537935	rs7594454	C	T	rs7594454	23089632	0.0000305	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	237537935	rs7594454	C	T	rs7594454	23089632	2.60E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	240539765	rs1030891	A	G	rs1030891	20201924	2.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	240539765	rs1030891	A	G	rs1030891	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	240685573	rs6748389	T	G	rs6748389	20201924	2.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	240695511	rs11674512	A	G	rs11674512	20201924	1.59E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
2	240695511	rs11674512	A	G	rs11674512	pha002891	1.59E-05	phs000125	2.05	[1.48-2.84]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	LOC150935	intron	NR_037808
3	108226	rs17042708	A	G	rs17042708	20201924	6.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	133412	rs6443038	G	A	rs6443038	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	148725	rs9856879	T	C	rs9856879	20201924	2.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	1374976	rs10510170	A	G	rs10510170	21956439	5.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	1389117	rs17038032	C	T	rs17038032	21314694	8.11E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	1985238	rs6783551	T	C	rs6783551	24277619	3.64E-04	NA	0.43	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
3	2616290	rs2728055	C	T	rs2728055	20201924	1.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	3158485	rs1153459	T	C	rs1153459	20201924	5.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	3356174	rs9874556	A	G	rs9874556	24962325	9.00E-06	NA	1.3	[1.18-1.42]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9874556-A	Research Support, N.I.H., Extramural	A	NA
3	7603708	rs1485179	C	T	rs1485179	21314694	6.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	8808515	rs237899	G	A	rs237899	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	9200375	rs17530358	G	A	rs17530358	24277619	3.80E-04	NA	0.86	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	SRGAP3
3	9449055	rs6443238	C	T	rs6443238	22096494	5.10E-08	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
3	9458307	rs11922615	A	G	rs11922615	22096494	2.60E-08	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
3	10292643	rs11707074	C	T	rs11707074	21314694	7.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	10301300	rs2241312	A	G	rs2241312	21314694	3.57E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	10958276	rs3774084	T	C	rs3774084	22096494	6.50E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
3	11239366	rs9822871	C	T	rs9822871	21703634	6.31E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
3	11244906	rs433303	C	T	rs433303	20202923	1.72E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	11244906	rs433303	C	T	rs433303	21956439	6.90E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	11253721	rs443137	G	A	rs443137	21703634	1.80E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
3	11956598	rs6777876	A	G	rs6777876	21314694	4.00E-07	AA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs6777876-G	Research Support, N.I.H., Extramural
3	12443844	rs4135275	A	G	rs4135275	20201924	1.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	12624580	rs13106	G	A	rs13106	20201924	7.96E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	13308740	rs357159	G	C	rs357159	21314694	6.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	14184669	rs8516	T	C	rs8516	21314694	2.08E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	14275759	rs6442433	C	G	rs6442433	21314694	7.22E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	14501174	rs12489456	G	A	rs12489456	21956439	4.00E-07	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	14511699	rs3773172	G	A	rs3773172	20201924	1.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	14511699	rs3773172	G	A	rs3773172	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	14512093	rs3773171	C	T	rs3773171	20201924	3.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	14512093	rs3773171	C	T	rs3773171	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	14513695	rs2289128	G	A	rs2289128	20201924	2.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	14513695	rs2289128	G	A	rs2289128	20201924	4.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	14517115	rs9834678	T	C	rs9834678	20201924	2.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	14517115	rs9834678	T	C	rs9834678	20201924	5.60E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	14517115	rs9834678	T	C	rs9834678	pha002893	5.65E-05	phs000125	2.56	[1.61-4.00]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	SLC6A6	intron	NM_003043
3	14524270	rs3773165	G	A	rs3773165	21956439	1.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	15295364	rs1318937	A	G	rs1318937	21956439	3.00E-06	EA + AA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	15559228	rs12495710	C	T	rs12495710	20201924	4.38E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	15559228	rs12495710	C	T	rs12495710	pha002891	4.38E-05	phs000125	5	[2.33-11.11]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T,C	COLQ	intron	NM_005677
3	15908766	rs4685266	A	G	rs4685266	20201924	2.72E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	16749024	rs9860475	C	T	rs9860475	20201924	4.05E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	16855953	rs6778524	T	C	rs6778524	21956439	9.00E-08	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	17049965	rs9876768	T	C	rs9876768	20201924	5.05E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	17394615	rs1374197	A	G	rs1374197	20201924	5.91E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	17433383	rs7647905	T	C	rs7647905	20201924	6.47E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	17615737	rs9823767	A	G	rs9823767	20201924	8.17E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	17774944	rs4908967	C	A	rs4908967	20201924	7.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	17784818	rs7627732	T	C	rs7627732	20201924	7.82E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	17792118	rs4349529	A	G	rs4349529	20201924	5.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	17798649	rs4611850	T	G	rs4611850	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	18610877	rs334960	C	T	rs334960	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	18656350	rs336605	G	T	rs336605	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	18693223	rs9855153	A	G	rs9855153	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	18704299	rs11914608	A	G	rs11914608	20201924	1.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	18704299	rs11914608	A	G	rs11914608	20201924	2.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	18704299	rs11914608	A	G	rs11914608	pha002892	1.42E-05	phs000125	1.45	[1.23-1.71]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
3	18728878	rs9845140	C	A	rs9845140	20201924	1.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	18737796	rs9826966	A	G	rs9826966	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	18804655	rs9847248	G	A	rs9847248	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	20192769	rs17678713	G	A	rs17678713	20201924	5.81E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	20720138	rs1500422	G	A	rs1500422	20201924	6.31E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	20738089	rs17809565	A	G	rs17809565	20201924	5.24E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	21736573	rs4488861	G	A	rs4488861	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	21882991	rs9836784	G	A	rs9836784	19581569	7.48E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
3	21895087	rs2336055	C	T	rs2336055	19581569	5.36E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
3	22229748	rs17010983	C	A	rs17010983	20201924	3.67E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	24631165	rs6795607	T	C	rs6795607	20201924	2.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	24631165	rs6795607	T	C	rs6795607	pha002893	2.36E-05	phs000125	1.96	[1.43-2.63]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
3	24636524	rs9819865	G	A	rs9819865	pha002893	6.81E-05	phs000125	1.82	[1.35-2.44]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
3	27100290	rs6766181	C	T	rs6766181	21529783	2.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	27170777	rs1522153	G	A	rs1522153	21956439	3.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	28188749	rs6803625	C	G	rs6803625	21314694	5.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	28328583	rs11706542	C	T	rs11706542	19581569	9.43E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
3	28736622	rs4398388	G	A	rs4398388	20201924	1.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	29287651	rs9877517	G	A	rs9877517	20201924	6.53E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	29287651	rs9877517	G	A	rs9877517	pha002891	6.53E-05	phs000125	3.23	[1.82-5.88]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
3	29482046	rs1438339	C	T	rs1438339	24277619	5.56E-04	NA	0.44	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	RBMS3
3	30332349	rs2077164	A	G	rs2077164	20201924	3.86E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	31804842	rs2168422	G	T	rs2168422	20201924	7.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	31810558	rs7612780	A	G	rs7612780	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	31817544	rs2219250	T	C	rs2219250	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	31817544	rs2219250	T	C	rs2219250	20201924	5.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	32240119	rs9825310	G	A	rs9825310	22004471	8.00E-06	NA	1.25	[1.14-1.38]	1,333 European ancestry cases; 2,168 European ancestry controls	European(3501)	ALL(3501)	EUR(3501)	ALL(3501)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	33243386	rs4389431	C	T	rs4389431	21314694	5.63E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	33289596	rs7653239	G	A	rs7653239	21314694	2.04E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	33698172	rs9876025	G	A	rs9876025	21314694	4.69E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	34427945	rs1529075	T	G	rs1529075	20201924	5.69E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	34446738	rs17031657	A	C	rs17031657	20201924	7.55E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	41230323	rs2691678	A	G	rs2691678	20201924	2.77E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	41484831	rs10446425	C	A	rs10446425	22096494	3.40E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
3	42226151	rs4234445	T	C	rs4234445	24277619	9.39E-04	NA	5.24	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	TRAK1
3	42265369	rs3774391	C	T	rs3774391	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	42800291	rs11915803	T	C	rs11915803	20201924	8.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	43473914	rs11710107	A	C	rs11710107	21529783	7.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	43484967	rs2888312	G	A	rs2888312	21529783	7.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	45293379	rs33786	G	A	rs33786	20201924	8.55E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	46774776	rs7639979	A	G	rs7639979	20201924	3.17E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	46777885	rs6808303	T	C	rs6808303	20201924	2.23E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	46778008	rs6793661	C	T	rs6793661	20201924	2.23E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	47159688	rs9828473	G	A	rs9828473	20201924	6.84E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	47902247	rs34675858	C	T	rs34675858	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	48209486	rs3731539	C	T	rs3731539	20201924	6.12E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	48450082	rs4858818	T	C	rs4858818	20201924	8.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50011021	rs2681779	T	C	rs2681779	20201924	6.15E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50011021	rs2681779	T	C	rs2681779	pha002891	6.15E-05	phs000125	4.55	[2.17-9.09]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	RBM6	intron	NM_001167582
3	50014114	rs2624821	G	A	rs2624821	20201924	6.07E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50014114	rs2624821	G	A	rs2624821	pha002891	6.07E-05	phs000125	5	[2.27-11.11]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	RBM6	intron	NM_001167582
3	50113004	rs2240328	T	C	rs2240328	20201924	6.81E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50132131	rs2624834	G	T	rs2624834	20201924	4.44E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50132131	rs2624834	G	T	rs2624834	pha002891	4.44E-05	phs000125	5.26	[2.38-11.11]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	RBM5	intron	NM_005778
3	50424814	rs7644782	A	G	rs7644782	20201924	2.54E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50430478	rs7612641	G	A	rs7612641	20201924	3.56E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50562566	rs12487817	T	C	rs12487817	20201924	4.33E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50614990	rs2232251	T	G	rs2232251	20201924	7.61E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	50751850	rs17051404	A	C	rs17051404	20201924	7.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51378548	rs7630259	G	A	rs7630259	20201924	8.13E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51382601	rs7642077	T	C	rs7642077	20201924	8.94E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51382652	rs7635095	C	T	rs7635095	20201924	8.94E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51387047	rs17051755	T	C	rs17051755	20201924	8.13E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51393046	rs4974096	G	A	rs4974096	20201924	8.18E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51393457	rs2306431	C	T	rs2306431	20201924	8.18E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51422188	rs1370124	A	G	rs1370124	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51425481	rs2304512	T	C	rs2304512	20201924	1.26E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51425674	rs2217938	A	G	rs2217938	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51430657	rs3804766	A	C	rs3804766	20201924	1.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51437597	rs3792408	A	G	rs3792408	20201924	1.42E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51441667	rs10510758	C	A	rs10510758	20201924	2.28E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51445146	rs2356261	C	A	rs2356261	20201924	1.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51457035	rs3749317	T	C	rs3749317	20201924	2.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51474182	rs17712228	G	A	rs17712228	20201924	1.37E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51483210	rs4687610	T	C	rs4687610	20201924	1.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51517653	rs3762714	G	A	rs3762714	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	51554042	rs4687605	T	C	rs4687605	20201924	8.45E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	53175557	rs7615501	G	A	rs7615501	20201924	8.23E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	54111877	rs750379	T	C	rs750379	21529783	3.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	54371791	rs11708620	C	T	rs11708620	21314694	5.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	54891599	rs6810058	G	T	rs6810058	20201924	6.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	55305884	rs459737	A	G	rs459737	20201924	3.99E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	55881520	rs6782906	C	T	rs6782906	20201924	2.26E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	55883396	rs7631846	T	C	rs7631846	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	55955214	rs17288603	G	A	rs17288603	20201924	7.82E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	56924711	rs11916112	G	A	rs11916112	20201924	7.29E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	58098444	rs7615893	T	C	rs7615893	21314694	6.97E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	58109748	rs4681800	T	A	rs4681800	21314694	8.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	58112488	rs2362904	C	T	rs2362904	20201924	2.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	58136429	rs4681795	T	C	rs4681795	20201924	1.70E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	58136429	rs4681795	T	C	rs4681795	pha002891	1.70E-05	phs000125	2.86	[1.75-4.55]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	FLNB	intron	NM_001457
3	58199669	rs4681824	T	G	rs4681824	21314694	6.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	59105913	rs2137457	G	A	rs2137457	21314694	6.48E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	60683737	rs1735457	G	A	rs1735457	20201924	6.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	60691605	rs1735460	T	C	rs1735460	20201924	3.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	60691605	rs1735460	T	C	rs1735460	20201924	3.70E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	60691605	rs1735460	T	C	rs1735460	pha002892	3.67E-05	phs000125	3.13	[1.82-5.26]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	FHIT	intron	NM_002012
3	60691605	rs1735460	T	C	rs1735460	pha002893	3.40E-05	phs000125	5.26	[2.44-12.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	FHIT	intron	NM_002012
3	60852438	rs17064083	C	G	rs17064083	21314694	1.13E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	61082153	rs9825823	T	C	rs9825823	20201924	2.13E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	61082153	rs9825823	T	C	rs9825823	pha002891	2.13E-05	phs000125	1.92	[1.43-2.63]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	FHIT	intron	NM_002012
3	61111195	rs6445194	G	T	rs6445194	20201924	1.28E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	61581049	rs4580548	C	G	rs4580548	21314694	9.96E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	64497351	rs4688470	A	C	rs4688470	20201924	5.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	68165772	rs9990002	G	T	rs9990002	20201924	3.52E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	68252679	rs7650009	A	G	rs7650009	20201924	3.17E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	68961010	rs6770678	C	T	rs6770678	21314694	5.29E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	69150277	rs6549184	G	A	rs6549184	20201924	1.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	72043000	rs9860628	C	T	rs9860628	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	73179320	rs9835056	T	C	rs9835056	20201924	9.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	73450198	rs3816831	G	A	rs3816831	21314694	3.79E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	73548335	rs12632755	C	T	rs12632755	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	73548335	rs12632755	C	T	rs12632755	20201924	5.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	73548400	rs12632758	C	T	rs12632758	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	73548400	rs12632758	C	T	rs12632758	20201924	6.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	74880857	rs1918392	A	G	rs1918392	20201924	5.22E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	82019603	rs7431326	G	A	rs7431326	20201924	6.49E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	84931323	rs1248820	T	C	rs1248820	21529783	5.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	86555969	rs2035985	C	T	rs2035985	24277619	3.22E-04	NA	0.85	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
3	93638017	rs7428007	A	G	rs7428007	21314694	4.77E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	97472556	rs6439361	G	A	rs6439361	20201924	4.37E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	97566573	rs699300	G	A	rs699300	21314694	8.74E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	97583676	rs3856567	A	G	rs3856567	20201924	5.38E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	97595379	rs6786354	G	A	rs6786354	20201924	6.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	97620528	rs1498652	A	C	rs1498652	20201924	4.88E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	97622697	rs4857068	C	A	rs4857068	20201924	8.07E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	97633737	rs1391665	T	C	rs1391665	20201924	7.65E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	99085806	rs2700667	G	A	rs2700667	20201924	4.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	99094790	rs2700586	C	T	rs2700586	20201924	3.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	99095896	rs2200019	C	T	rs2200019	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	99107683	rs2700648	G	A	rs2700648	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	100263559	rs4928112	G	A	rs4928112	20201924	2.24E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	102406978	rs10212345	C	T	rs10212345	20201924	2.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	102436522	rs9873502	G	T	rs9873502	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	102467051	rs9860789	A	G	rs9860789	20201924	2.23E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	102834800	rs9832587	T	C	rs9832587	20201924	5.65E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	103635435	rs4132806	C	T	rs4132806	24277619	1.05E-04	NA	0.53	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
3	103648320	rs6765661	A	G	rs6765661	24277619	5.14E-04	NA	0.58	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
3	107185073	rs1850344	A	G	rs1850344	20201924	4.70E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	107185073	rs1850344	A	G	rs1850344	23691058	0.00000816	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	107185073	rs1850344	A	G	rs1850344	pha002892	4.72E-05	phs000125	1.43	[1.20-1.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
3	107187344	rs1429	C	T	rs1429	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	107202624	rs10511261	C	A	rs10511261	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	107233097	rs10511260	T	G	rs10511260	20201924	3.40E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	107233097	rs10511260	T	G	rs10511260	20201924	4.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	107233097	rs10511260	T	G	rs10511260	pha002892	3.41E-06	phs000125	1.54	[1.28-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
3	108725984	rs2044590	G	C	rs2044590	21314694	9.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	110501848	rs1462307	T	C	rs1462307	20201924	4.76E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	112604252	rs9876981	G	T	rs9876981	21314694	8.18E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	113560020	rs2566980	A	C	rs2566980	24277619	3.46E-04	NA	0.77	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	GRAMD1C
3	115740719	rs16824395	A	G	rs16824395	24962325	6.00E-06	NA	1.92	[1.63-2.21]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs16824395-A	Research Support, N.I.H., Extramural	A	LSAMP
3	115758068	rs62271282	T	G	rs62271282	24962325	9.16E-06	NA	1.96	[1.67-2.25]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	T	LSAMP
3	118157897	rs577196	C	T	rs577196	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	120350505	rs7613732	A	G	rs7613732	21314694	3.82E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	120690203	rs12491742	T	G	rs12491742	21314694	6.40E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	121486310	rs4413346	T	C	rs4413346	21314694	9.68E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	121556219	rs9826473	C	T	rs9826473	21314694	7.75E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	124297645	rs6438847	A	C	rs6438847	24277619	3.02E-04	NA	0.49	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	KALRN
3	124545750	rs6771896	G	A	rs6771896	24277619	3.63E-04	NA	0.58	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ITGB5
3	124610238	rs7373878	G	T	rs7373878	24277619	9.70E-04	NA	0.51	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
3	127548479	rs1525855	G	A	rs1525855	21314694	8.29E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	127931340	rs2999090	G	A	rs2999090	21314694	3.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	131775316	rs12634678	T	G	rs12634678	21314694	1.19E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	131984388	rs924949	G	A	rs924949	21314694	5.33E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	132693588	rs2369955	A	C	rs2369955	21529783	2.00E-06	NA	0.14	[NA] unit decrease	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs2369955-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	132800146	rs10935045	C	A	rs10935045	21529783	1.70E-06	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	134469531	rs10935129	T	A	rs10935129	21314694	7.59E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	135587811	rs1401543	T	C	rs1401543	21314694	4.02E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	137681448	rs6439772	A	G	rs6439772	21314694	4.26E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	138089824	rs1199335	A	G	rs1199335	21314694	8.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	138313834	rs529615	C	T	rs529615	21314694	2.82E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	138400332	rs12493155	C	T	rs12493155	21314694	7.31E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	139405342	rs10935342	T	C	rs10935342	21529783	6.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	139447500	rs10935348	C	A	rs10935348	21529783	2.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	139993694	rs7626587	A	G	rs7626587	20201924	8.08E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	139997148	rs4077501	T	C	rs4077501	20201924	1.53E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	140009220	rs6439914	A	G	rs6439914	20201924	7.96E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	140307406	rs347964	A	G	rs347964	21314694	5.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	142444625	rs13094259	G	T	rs13094259	20201924	6.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	142510348	rs9815607	G	A	rs9815607	20201924	7.95E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	142541687	rs9841007	T	C	rs9841007	20201924	1.52E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	142994194	rs7639109	C	T	rs7639109	21314694	7.92E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	143049769	rs7431637	T	C	rs7431637	23089632	0.00000758	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	143049769	rs7431637	T	C	rs7431637	23089632	0.00036	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	143068250	rs10446322	A	G	rs10446322	23089632	0.00000173	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	143068250	rs10446322	A	G	rs10446322	23089632	0.0000577	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	143085345	rs868702	G	A	rs868702	23089632	0.0000258	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	143085345	rs868702	G	A	rs868702	23089632	1.73E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	143177248	rs1723034	C	T	rs1723034	20201924	4.77E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	143178526	rs838610	A	C	rs838610	20201924	4.23E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	143188053	rs838621	C	T	rs838621	20201924	4.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	147712979	rs2061668	C	A	rs2061668	20201924	1.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	147712979	rs2061668	C	A	rs2061668	20201924	3.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	147712979	rs2061668	C	A	rs2061668	pha002892	1.64E-05	phs000125	1.43	[1.22-1.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
3	147712979	rs2061668	C	A	rs2061668	pha002893	3.39E-05	phs000125	1.49	[1.23-1.80]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
3	149340813	rs1344815	A	G	rs1344815	20201924	7.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	149344615	rs9857773	C	A	rs9857773	20201924	4.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	149347047	rs6790596	G	A	rs6790596	20201924	4.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	149347047	rs6790596	G	A	rs6790596	20201924	4.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	149347571	rs7638140	G	A	rs7638140	20201924	3.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	149347571	rs7638140	G	A	rs7638140	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	151514705	rs9874357	T	C	rs9874357	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	153027489	rs9822442	T	C	rs9822442	20201924	4.61E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	153316224	rs3961460	T	C	rs3961460	21529783	1.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	161229214	rs17479823	C	T	rs17479823	21703634	2.67E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
3	164520763	rs57350471	T	A	rs57350471	24962325	2.11E-08	NA	1.45	[1.31-1.59]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs57350471-A	Research Support, N.I.H., Extramural	T	NA
3	164520783	rs9871275	C	T	rs9871275	24962325	2.11E-08	NA	1.45	[1.31-1.59]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9871275-T	Research Support, N.I.H., Extramural	C	NA
3	164520853	rs9875364	G	C	rs9875364	24962325	2.06E-08	NA	1.44	[1.30-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9875364-C	Research Support, N.I.H., Extramural	G	NA
3	164531227	rs9862987	A	C	rs9862987	24962325	4.31E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9862987-C	Research Support, N.I.H., Extramural	A	NA
3	164534026	rs10936425	A	G	rs10936425	24962325	6.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10936425-G	Research Support, N.I.H., Extramural	A	NA
3	164535514	rs9838822	T	C	rs9838822	24962325	6.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9838822-C	Research Support, N.I.H., Extramural	T	NA
3	164540649	rs10433463	G	A	rs10433463	24962325	6.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10433463-A	Research Support, N.I.H., Extramural	G	NA
3	164542525	rs9876205	T	C	rs9876205	24962325	6.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9876205-C	Research Support, N.I.H., Extramural	T	NA
3	164543628	rs9824015	A	G	rs28675270	24962325	6.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs28675270-G	Research Support, N.I.H., Extramural	T	NA
3	164546258	rs9849299	G	A	rs9849299	24962325	6.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9849299-A	Research Support, N.I.H., Extramural	G	NA
3	164549686	rs57369046	T	C	rs57369046	24962325	6.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs57369046-C	Research Support, N.I.H., Extramural	T	NA
3	164551044	rs7633723	T	C	rs7633723	24962325	6.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7633723-C	Research Support, N.I.H., Extramural	T	NA
3	164552132	rs9825394	T	C	rs9825394	24962325	8.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9825394-C	Research Support, N.I.H., Extramural	T	NA
3	164553575	rs9831395	T	C	rs9831395	24962325	5.55E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9831395-C	Research Support, N.I.H., Extramural	C	NA
3	164554023	rs9816120	G	T	rs9816120	24962325	8.06E-08	NA	1.43	[1.29-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9816120-T	Research Support, N.I.H., Extramural	G	NA
3	164554801	rs9817317	G	A	rs9817317	24962325	9.29E-09	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9817317-A	Research Support, N.I.H., Extramural	A	NA
3	164555706	rs7630142	A	G	rs7630142	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7630142-G	Research Support, N.I.H., Extramural	A	NA
3	164556648	rs9874932	G	A	rs9874932	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9874932-A	Research Support, N.I.H., Extramural	G	NA
3	164557575	rs9824625	T	C	rs9824625	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9824625-C	Research Support, N.I.H., Extramural	T	NA
3	164557652	rs9880338	G	A	rs9880338	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9880338-A	Research Support, N.I.H., Extramural	G	NA
3	164557917	rs4541411	T	C	rs4541411	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs4541411-C	Research Support, N.I.H., Extramural	T	NA
3	164558595	rs9847462	A	G	rs9847462	23089632	6.65E-07	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	164558595	rs9847462	A	G	rs9847462	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9847462-G	Research Support, N.I.H., Extramural	A	NA
3	164559430	rs28821642	C	T	rs28821642	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs28821642-T	Research Support, N.I.H., Extramural	C	NA
3	164560182	rs7645282	A	G	rs7645282	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7645282-G	Research Support, N.I.H., Extramural	G	NA
3	164560194	rs7647704	T	A	rs7647704	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7647704-A	Research Support, N.I.H., Extramural	A	NA
3	164562164	rs7640074	C	T	rs7640074	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7640074-T	Research Support, N.I.H., Extramural	A	NA
3	164563201	rs9855885	T	C	rs9855885	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9855885-C	Research Support, N.I.H., Extramural	T	NA
3	164563390	rs9873722	A	G	rs9873722	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9873722-G	Research Support, N.I.H., Extramural	A	NA
3	164565763	rs9819217	C	T	rs9819217	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9819217-T	Research Support, N.I.H., Extramural	C	NA
3	164567759	rs79139973	G	GTAAA	rs9830200	24962325	2.91E-08	NA	1.44	[1.30-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9830200-G	Research Support, N.I.H., Extramural	NA	NA
3	164567759	rs9830200	G	A	rs9830200	24962325	2.91E-08	NA	1.44	[1.30-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9830200-G	Research Support, N.I.H., Extramural	NA	NA
3	164568563	rs9290244	T	G	rs9290244	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9290244-G	Research Support, N.I.H., Extramural	T	NA
3	164571138	rs7628882	G	A	rs7628882	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7628882-A	Research Support, N.I.H., Extramural	A	NA
3	164573311	rs9881091	T	G	rs9881091	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9881091-G	Research Support, N.I.H., Extramural	T	NA
3	164578266	rs4602392	C	T	rs4602392	24962325	2.07E-08	NA	1.44	[1.32-1.56]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs4602392-T	Research Support, N.I.H., Extramural	C	NA
3	164579310	rs9865078	G	A	rs9865078	24962325	9.71E-09	NA	1.45	[1.33-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9865078-A	Research Support, N.I.H., Extramural	G	NA
3	164580672	rs7619524	C	T	rs7619524	24962325	9.71E-09	NA	1.45	[1.33-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7619524-T	Research Support, N.I.H., Extramural	T,C	NA
3	164585575	rs6791103	A	C	rs6791103	24962325	8.85E-09	NA	1.45	[1.33-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6791103-C	Research Support, N.I.H., Extramural	A	NA
3	164586715	rs5023277	C	G	rs5023277	24962325	4.99E-09	NA	1.46	[1.34-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs5023277-G	Research Support, N.I.H., Extramural	G	NA
3	164587302	rs9879548	G	T	rs9879548	24962325	4.99E-09	NA	1.46	[1.34-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9879548-T	Research Support, N.I.H., Extramural	G	NA
3	164587350	rs7641732	A	T	rs7641732	24962325	4.99E-09	NA	1.46	[1.34-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7641732-T	Research Support, N.I.H., Extramural	A	NA
3	164587559	rs6808582	G	A	rs6808582	24962325	4.99E-09	NA	1.46	[1.34-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6808582-A	Research Support, N.I.H., Extramural	G	NA
3	164588205	rs6763281	G	T	rs6763281	24962325	9.02E-09	NA	1.45	[1.33-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6763281-T	Research Support, N.I.H., Extramural	G	NA
3	164588388	rs6788557	C	G	rs6788557	24962325	4.99E-09	NA	1.46	[1.34-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6788557-G	Research Support, N.I.H., Extramural	G	NA
3	164588702	rs9810313	G	T	rs9810313	23089632	4.14E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	164588702	rs9810313	G	T	rs9810313	24962325	6.95E-09	NA	1.45	[1.33-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9810313-T	Research Support, N.I.H., Extramural	T	NA
3	164589150	rs56303997	G	A	rs56303997	24962325	9.02E-09	NA	1.45	[1.33-1.57]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs56303997-A	Research Support, N.I.H., Extramural	G	NA
3	164589939	rs2168784	C	T	rs2168784	24962325	5.00E-09	NA	1.46	[1.34-1.58]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2168784-T	Research Support, N.I.H., Extramural	T	NA
3	164836372	rs11916446	G	T	rs11916446	21529783	9.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	166028706	rs526992	T	C	rs526992	21956439	4.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	167119945	rs13074970	C	T	rs13074970	21314694	6.63E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	167175247	rs4955672	C	G	rs4955672	21314694	9.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	168742461	rs1420469	T	C	rs1420469	24277619	2.37E-04	NA	4.81	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
3	170831072	rs4955765	G	A	rs4955765	21314694	4.05E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	171095094	rs11926949	T	C	rs11926949	20201924	6.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	172215637	rs2041692	T	C	rs2041692	20201924	7.67E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	176031687	rs9835842	A	G	rs9835842	20201924	1.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	176807314	rs1201284	G	A	rs1201284	19581569	1.76E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
3	176827927	rs1209035	T	C	rs1209035	19581569	3.96E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
3	176868053	rs7632766	T	C	rs7632766	21314694	9.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	177113056	rs9850957	C	T	rs9850957	20201924	4.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	178910350	rs17592582	T	C	rs17592582	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	182459069	rs4384980	A	C	rs4384980	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	182459069	rs4384980	A	C	rs4384980	23691058	0.000000578	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	183095982	rs12635655	C	T	rs12635655	20201924	5.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	183635768	rs1000002	C	T	rs1000002	21314694	9.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	183901389	rs13262	T	C	rs13262	20201924	3.42E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	184216130	rs3930234	T	C	rs3930234	21529783	8.00E-06	NA	0.1	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol use disorder factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D019973	Alcohol-Related Disorders	NA	NA	Drug abuse	rs3930234-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	184475833	rs9883278	G	A	rs9883278	21314694	8.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	185357531	rs9864104	C	T	rs9864104	21314694	4.87E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	186293820	rs2280390	T	G	rs2280390	21314694	5.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	190637833	rs6778263	C	A	rs6778263	24277619	2.52E-04	NA	0.48	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
3	190714587	rs9864764	A	C	rs9864764	24277619	8.67E-04	NA	0.99	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
3	191847799	rs6779599	C	A	rs6779599	21314694	1.98E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
3	192614308	rs4455277	T	C	rs4455277	20201924	1.90E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	192614308	rs4455277	T	C	rs4455277	pha002892	1.94E-05	phs000125	1.45	[1.22-1.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	MB21D2	intron	NM_178496
3	192614483	rs3952738	T	C	rs3952738	20201924	1.90E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	192614483	rs3952738	T	C	rs3952738	pha002892	1.94E-05	phs000125	1.45	[1.22-1.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	MB21D2	intron	NM_178496
3	192619383	rs7643379	A	G	rs7643379	20201924	5.20E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	192619383	rs7643379	A	G	rs7643379	pha002892	5.25E-06	phs000125	1.49	[1.25-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	MB21D2	intron	NM_178496
3	192625190	rs9869202	C	T	rs9869202	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	194119583	rs1572840	G	A	rs1572840	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
3	196414159	rs843511	C	T	rs843511	21314694	4.31E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	517198	rs7678962	G	A	rs7678962	21314694	2.21E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	3028113	rs2857845	A	T	rs2857845	21314694	3.60E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	3036630	rs2857839	T	C	rs2857839	20201924	2.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	3036630	rs2857839	T	C	rs2857839	23691058	0.0000066	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	3039150	rs1801058	T	C	rs1801058	20201924	2.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	3039150	rs1801058	T	C	rs1801058	20201924	9.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	3039150	rs1801058	T	C	rs1801058	23691058	0.00000648	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	3040587	rs2798303	T	C	rs2798303	20201924	1.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	3040587	rs2798303	T	C	rs2798303	20201924	2.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	3040587	rs2798303	T	C	rs2798303	23691058	0.00000128	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	3396963	rs11732375	G	A	rs11732375	20201924	6.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	3409024	rs16844280	C	T	rs16844280	20201924	2.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	4249300	rs2916468	T	C	rs2916468	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	4249620	rs2916464	T	C	rs2916464	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	4393068	rs3792686	T	C	rs3792686	22096494	5.80E-07	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
4	4719494	rs1000579	A	G	rs1000579	22004471	4.00E-07	NA	1.3	[1.17-1.43]	1,333 European ancestry cases; 2,168 European ancestry controls	European(3501)	ALL(3501)	EUR(3501)	ALL(3501)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	5838837	rs7654446	G	A	rs7654446	21314694	4.89E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	5945106	rs7682973	A	G	rs7682973	24277619	8.23E-04	NA	0.88	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
4	5964345	rs6446414	T	C	rs6446414	24277619	2.44E-04	NA	0.65	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	C4orf50
4	6675529	rs28620095	A	G	rs28620095	20201924	3.55E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	13715121	rs10939500	C	A	rs10939500	21314694	3.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	13815155	rs10939516	A	G	rs10939516	20201924	5.11E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	18072500	rs1563749	C	T	rs1563749	21529783	7.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	18079517	rs9291662	G	A	rs9291662	21529783	1.00E-04	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	18162104	rs2320289	A	C	rs2320289	21529783	4.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
4	22832682	rs439863	A	G	rs439863	20201924	5.91E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	24060605	rs647381	A	G	rs647381	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	25183445	rs13106651	A	G	rs13106651	21314694	3.83E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	25200584	rs1909475	T	C	rs1909475	21314694	1.35E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	26025756	rs4269167	T	C	rs4269167	24277619	5.10E-05	NA	0.75	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
4	30544014	rs11727470	A	G	rs11727470	20202923	9.68E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	31660739	rs11944702	T	C	rs11944702	24277619	4.52E-04	NA	0.52	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
4	31791952	rs10029539	T	C	rs10029539	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	31793650	rs6811255	G	T	rs6811255	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	31863889	rs1523145	T	C	rs1523145	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	31966758	rs7683244	G	T	rs7683244	20201924	3.45E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	32477273	rs4862932	T	C	rs4862932	21529783	7.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	38458620	rs1004064	G	A	rs1004064	21529783	8.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	41307008	rs1453048	C	T	rs1453048	21314694	7.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	55620032	rs17084794	C	A	rs17084794	21314694	1.40E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	55980456	rs2305949	C	T	rs2305949	21703634	3.46E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
4	59720431	rs7685041	G	A	rs7685041	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	59734211	rs28570064	A	G	rs28570064	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	59805404	rs4074334	G	T	rs4074334	20201924	7.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	63842062	rs2660598	G	A	rs2660598	24277619	2.31E-04	NA	0.47	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
4	68309566	rs6810410	T	C	rs6810410	20201924	3.57E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	68314440	rs7681618	A	G	rs7681618	20201924	2.77E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	68335971	rs11946612	T	C	rs11946612	20201924	7.07E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	68337435	rs1874633	A	G	rs1874633	20201924	3.03E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	71165706	rs729314	C	A	rs729314	20201924	3.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	71185721	rs11947897	C	A	rs11947897	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	71190301	rs717360	C	T	rs717360	19581569	7.94E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
4	71329490	rs1109501	G	A	rs1109501	21529783	5.00E-06	NA	0.1	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs1109501-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	71353508	rs6600832	C	T	rs6600832	21529783	3.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	72022775	rs17689531	T	C	rs17689531	21314694	7.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	72063044	rs2198341	G	A	rs2198341	24277619	7.24E-04	NA	0.47	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	SLC4A4
4	73931526	rs4694155	T	G	rs4694155	20201924	5.26E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	74626945	rs2886920	C	T	rs2886920	21314694	2.52E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	80491820	rs2165387	T	C	rs2165387	20201924	1.96E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	80753792	rs10031299	T	C	rs10031299	20201924	6.69E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	81061422	rs12513014	A	G	rs12513014	23089632	0.0000138	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	81073672	rs13102102	T	C	rs13102102	23089632	0.0000111	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	81073672	rs13102102	T	C	rs13102102	23089632	0.0000137	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	81087073	rs13138779	G	A	rs13138779	23089632	0.00000975	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	81087073	rs13138779	G	A	rs13138779	23089632	0.000769	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	81250441	rs2867709	C	A	rs2867709	21529783	9.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	82432069	rs4437240	C	A,G,T	rs4437240	21314694	8.14E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	83644726	rs12500169	C	G	rs12500169	21314694	6.98E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	86463558	rs1994074	T	C	rs1994074	21314694	6.15E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	88905903	rs7655182	G	A	rs7655182	21314694	2.23E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	89478101	rs10516812	C	T	rs10516812	21529783	7.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	90780902	rs6532194	C	T	rs6532194	21703634	9.69E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
4	91642911	rs13134142	T	G	rs13134142	19581569	3.67E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
4	95058293	rs9992640	A	G	rs9992640	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	100239319	rs1229984	T	C	rs1229984	23456092	3.00E-21	NA	2.35	[1.95-2.84]	117 Korean ancestry cases; 279 Korean ancestry controls	Korean(396)	ALL(396)	ASN(396)	ALL(396)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, Non-U.S. Gov't	G	ADH1B
4	100250419	rs1789891	C	A	rs1789891	22004471	1.00E-08	NA	1.46	[1.28-1.67]	1,333 European ancestry cases; 2,168 European ancestry controls	European(3501)	ALL(3501)	EUR(3501)	ALL(3501)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	100257907	rs2298753	T	C	rs2298753	21314694	8.11E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	108449838	rs17037826	A	C	rs17037826	20201924	4.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	108455221	rs1913586	T	C	rs1913586	21314694	5.43E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	110194284	rs6857726	C	A	rs6857726	21314694	9.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	110509186	rs12640500	G	T	rs12640500	21314694	3.07E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	113150288	rs9307379	G	C	rs9307379	21314694	7.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	113465651	rs1486865	A	G	rs1486865	20201924	6.18E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	113469913	rs4833414	T	C	rs4833414	20201924	5.62E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	113485372	rs9991830	T	C	rs9991830	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	113488134	rs2029211	T	C	rs2029211	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	113529834	rs9307383	C	T	rs9307383	20201924	6.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	113536080	rs2087111	A	G	rs2087111	20201924	8.36E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	113558602	rs13146963	A	G	rs13146963	20201924	4.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	114589266	rs6533710	A	G	rs6533710	20201924	6.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	114877120	rs10012206	T	C	rs10012206	21314694	1.84E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	115957593	rs13150562	T	C	rs13150562	19581569	7.00E-06	NA	1.27	[1.14-1.41]	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs13150562-G	Multicenter Study	Research Support, Non-U.S. Gov't	T
4	119408351	rs17642621	G	A	rs17642621	24277619	4.36E-04	NA	0.47	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
4	119865067	rs4834729	C	T	rs4834729	21314694	4.36E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	122300295	rs523815	G	A	rs523815	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	122899165	rs6838639	G	A	rs6838639	21314694	9.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	124477700	rs4076851	G	A	rs4076851	20201924	1.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	124483312	rs6813400	A	C	rs6813400	20201924	1.43E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	124592136	rs2589839	T	C	rs2589839	20201924	3.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	126007196	rs2390798	G	A	rs2390798	20201924	1.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	130962263	rs1567193	T	C	rs1567193	24277619	8.08E-06	NA	0.53	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
4	130978989	rs6534762	A	G	rs6534762	24277619	2.90E-05	NA	0.5	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
4	131013140	rs11933661	C	T	rs11933661	24277619	4.00E-06	NA	0.54	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
4	135686477	rs548172	T	C	rs548172	24277619	9.43E-04	NA	0.49	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
4	135735591	rs13144694	A	G	rs13144694	24277619	3.09E-04	NA	0.43	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
4	135735591	rs200733877	AT	A	rs13144694	24277619	3.09E-04	NA	0.43	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
4	139157996	rs11723658	C	A	rs11723658	20201924	4.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	142530609	rs1519548	C	T	rs1519548	20201924	2.88E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	143098939	rs9308148	A	G	rs9308148	21314694	7.79E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	146369756	rs13109195	T	C	rs13109195	20201924	1.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	146369756	rs13109195	T	C	rs13109195	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	147551074	rs970674	G	A	rs970674	20201924	7.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	150128848	rs17487852	A	G	rs17487852	21956439	4.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	151775259	rs11099777	G	A	rs11099777	21314694	5.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	153982885	rs6832907	A	G	rs6832907	21314694	9.61E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	154559151	rs2033831	A	G	rs2033831	21314694	8.73E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	154654323	rs4145338	T	C	rs4145338	21314694	7.67E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	157089605	rs5027023	C	A	rs5027023	24277619	8.18E-04	NA	0.44	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
4	157712959	rs12651147	C	T	rs12651147	21314694	9.39E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	160749263	rs1457805	C	A	rs1457805	20201924	7.15E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	162764014	rs1440588	A	G	rs1440588	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	163243053	rs4440177	G	A	rs4440177	23942779	6.00E-06	NA	0.35	[NA] unit increase	7,188 European ancestry individuals	European(7188)	ALL(7188)	EUR(7188)	ALL(7188)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs4440177-A	Twin Study	Research Support, N.I.H., Extramural	A
4	166335181	rs729699	C	A,T	rs729699	21703634	6.39E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
4	166384367	rs6536915	C	T	rs6536915	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	167422116	rs978230	C	T	rs978230	24277619	8.78E-04	NA	0.46	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
4	167454287	rs12506794	C	T	rs12506794	24277619	7.64E-04	NA	0.4	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
4	167528623	rs6536987	A	G	rs6536987	24277619	1.25E-04	NA	0.66	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
4	169672630	rs6831359	A	G	rs6831359	21314694	8.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	175740569	rs6824735	T	C	rs6824735	pha002893	3.90E-05	phs000125	1.58	[1.27-1.96]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	GLRA3	intron	NM_001042543
4	179046619	rs553372	G	A	rs553372	20201924	6.23E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	179279965	rs2705962	A	G	rs2705962	20201924	7.76E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	179290393	rs2705988	G	A	rs2705988	20201924	7.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	179307893	rs1567479	G	A	rs1567479	20201924	6.33E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	180466309	rs10017041	T	C	rs10017041	20201924	2.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	180899465	rs17769849	C	T	rs17769849	20201924	5.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	180902914	rs6836406	A	G	rs6836406	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	182576586	rs6552517	C	T	rs6552517	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	183929581	rs1377943	C	T	rs1377943	21314694	9.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	185109994	rs6552767	G	A	rs6552767	21314694	9.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	185123766	rs1882331	T	C	rs1882331	21529783	1.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	185892515	rs10009538	C	T	rs10009538	21314694	8.52E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
4	186046473	rs6818704	A	G	rs6818704	20201924	4.66E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
4	186046473	rs6818704	A	G	rs6818704	pha002891	4.66E-05	phs000125	2.01	[1.44-2.81]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
4	188698095	rs7683009	C	T	rs7683009	22096494	4.20E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
5	964250	rs16868701	G	A	rs16868701	21314694	8.48E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	1512208	rs2963282	G	A	rs2963282	20201924	2.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	1519197	rs4608970	T	C	rs4608970	20201924	2.30E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	1519197	rs4608970	T	C	rs4608970	20201924	8.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	1519197	rs4608970	T	C	rs4608970	pha002892	8.48E-05	phs000125	2.03	[1.43-2.90]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	LPCAT1	intron	NM_024830
5	1519197	rs4608970	T	C	rs4608970	pha002893	2.35E-05	phs000125	2.33	[1.58-3.46]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	LPCAT1	intron	NM_024830
5	1536257	rs4551123	A	G	rs4551123	20201924	4.30E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	1536257	rs4551123	A	G	rs4551123	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	1536257	rs4551123	A	G	rs4551123	pha002893	4.31E-05	phs000125	2.19	[1.50-3.18]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
5	1744484	rs1392466	G	A	rs1392466	24277619	5.50E-04	NA	0.42	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
5	2549211	rs7702425	A	G	rs7702425	20201924	8.36E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	2553159	rs6888228	T	C	rs6888228	20201924	2.34E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	3139158	rs597099	C	T	rs597099	24277619	9.50E-05	NA	0.44	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
5	3616637	rs7729527	T	C	rs7729527	21314694	6.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	3677182	rs871879	G	A	rs871879	21314694	2.14E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	6317306	rs12716179	T	C	rs12716179	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	6317306	rs12716179	T	C	rs12716179	20201924	5.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	6325850	rs4345283	A	C	rs4345283	20201924	8.22E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	9380110	rs1805243	T	C	rs1805243	20201924	4.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	9380110	rs1805243	T	C	rs1805243	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	9403974	rs268487	A	G	rs268487	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	9550642	rs930076	T	C	rs930076	21703634	1.67E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	9987734	rs1896785	A	G	rs1896785	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	9987734	rs1896785	A	G	rs1896785	20201924	5.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	10903781	rs1995364	A	G	rs1995364	23089632	8.79E-07	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	11300854	rs6869903	T	C	rs6869903	20201924	3.47E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	12975322	rs1017454	G	A	rs1017454	20201924	2.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	12975322	rs1017454	G	A	rs1017454	20201924	9.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	12975934	rs17237639	A	G	rs17237639	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13374095	rs1037112	A	G	rs1037112	20201924	1.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13374095	rs1037112	A	G	rs1037112	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13394171	rs985765	G	A	rs985765	20201924	1.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13394171	rs985765	G	A	rs985765	20201924	2.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13394171	rs985765	G	A	rs985765	pha002893	9.96E-05	phs000125	1.52	[1.23-1.88]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
5	13399634	rs7721685	A	G	rs7721685	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13399634	rs7721685	A	G	rs7721685	20201924	6.60E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13399634	rs7721685	A	G	rs7721685	pha002893	6.64E-05	phs000125	1.54	[1.25-1.90]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
5	13450794	rs1864097	C	T	rs1864097	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13450794	rs1864097	C	T	rs1864097	20201924	6.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	13450794	rs1864097	C	T	rs1864097	pha002893	6.42E-05	phs000125	1.49	[1.23-1.82]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
5	13834706	rs16902820	T	G	rs16902820	21314694	9.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	13993530	rs7727798	T	C	rs7727798	20201924	6.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	16272637	rs2582662	G	A	rs2582662	21529783	2.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
5	16449037	rs154791	G	A	rs154791	21314694	2.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	16617903	rs35004	C	A	rs35004	20201924	8.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	16818363	rs12188582	A	G	rs12188582	20201924	8.33E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	16822171	rs10063505	C	A	rs10063505	20201924	8.86E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	16910605	rs29452	C	A	rs29452	20201924	6.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	23532643	rs6889665	T	C	rs6889665	20201924	5.53E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	23579740	rs16892567	G	A	rs16892567	21314694	5.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	24884260	rs1389221	T	C	rs1389221	21529783	6.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	25717507	rs400196	A	G	rs400196	20201924	8.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	28696504	rs16897978	C	A	rs16897978	24962325	5.00E-06	NA	1.53	[1.35-1.71]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs16897978-C	Research Support, N.I.H., Extramural	C	NA
5	28696590	rs11747943	A	G	rs11747943	24962325	9.10E-06	NA	1.47	[1.29-1.65]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11747943-A	Research Support, N.I.H., Extramural	A	NA
5	31200936	rs7716554	G	A	rs7716554	21314694	8.27E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	31804573	rs7731219	A	G	rs7731219	21314694	9.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	31818948	rs4867084	G	A	rs4867084	21314694	6.51E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	32215515	rs8180531	T	C	rs8180531	20201924	2.89E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	32275467	rs4078204	G	A	rs4078204	20201924	1.28E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	32439324	rs641221	A	G	rs641221	21314694	7.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	37918703	rs2216712	C	T	rs2216712	21529783	7.90E-06	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	40134777	rs2548145	G	A	rs2548145	21529783	2.00E-06	NA	0.08	[NA] unit decrease	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol use disorder factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D019973	Alcohol-Related Disorders	NA	NA	Drug abuse	rs2548145-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	44012472	rs4587082	C	A	rs4587082	20201924	4.14E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	45393261	rs6874279	G	A	rs6874279	20201924	5.08E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	45393261	rs6874279	G	A	rs6874279	pha002891	5.08E-05	phs000125	2.03	[1.44-2.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	HCN1	intron	NM_021072
5	46160787	rs8185226	T	C	rs8185226	20201924	8.11E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	46192220	rs7293423	G	A	rs7293423	20201924	3.71E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	46211903	rs11958464	C	T	rs11958464	20201924	3.71E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	46332383	rs7293345	C	T	rs7293345	20201924	6.39E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49488236	rs7293378	G	A	rs7293378	20201924	1.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49522346	rs559096	C	T	rs559096	20201924	9.08E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49522346	rs559096	C	T	rs559096	pha002891	9.08E-05	phs000125	1.85	[1.35-2.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	NA	NA	NA	NA
5	49564628	rs1674512	G	A	rs1674512	20201924	9.15E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49564628	rs1674512	G	A	rs1674512	pha002891	9.15E-05	phs000125	1.85	[1.37-2.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
5	49575177	rs4865676	A	C	rs4865676	20201924	9.06E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49575177	rs4865676	A	C	rs4865676	pha002891	9.06E-05	phs000125	1.85	[1.37-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
5	49632762	rs10064702	T	G	rs10064702	20201924	9.15E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49632762	rs10064702	T	G	rs10064702	pha002891	9.15E-05	phs000125	1.85	[1.35-2.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
5	49645820	rs7710841	C	T	rs7710841	20201924	9.06E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49645820	rs7710841	C	T	rs7710841	pha002891	9.06E-05	phs000125	1.85	[1.37-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
5	49682163	rs10042504	A	G	rs10042504	20201924	9.15E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49682163	rs10042504	A	G	rs10042504	pha002891	9.15E-05	phs000125	1.85	[1.37-2.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
5	49696932	rs2036902	A	G	rs2036902	20201924	9.88E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49696932	rs2036902	A	G	rs2036902	pha002891	9.88E-05	phs000125	1.85	[1.35-2.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	EMB	intron	NM_198449
5	49739908	rs13157992	C	T	rs13157992	20201924	9.03E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49739908	rs13157992	C	T	rs13157992	pha002891	9.03E-05	phs000125	1.85	[1.37-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
5	49746323	rs7720960	A	G	rs7720960	20201924	7.28E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49746323	rs7720960	A	G	rs7720960	pha002891	7.28E-05	phs000125	1.89	[1.37-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
5	49767759	rs7378969	T	C	rs7378969	20201924	6.04E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49767759	rs7378969	T	C	rs7378969	pha002891	6.04E-05	phs000125	1.89	[1.39-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T,C	NA	NA	NA
5	49786597	rs1016620	A	G	rs1016620	20201924	9.80E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	49786597	rs1016620	A	G	rs1016620	pha002891	9.80E-05	phs000125	1.12	[0.82-1.54]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
5	49798429	rs10940335	T	C	rs10940335	20201924	1.26E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	53531305	rs33282	C	T	rs33282	24962325	2.09E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs33282-C	Research Support, N.I.H., Extramural	T	ARL15
5	53535247	rs3910951	C	T	rs3910951	24962325	4.69E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs3910951-C	Research Support, N.I.H., Extramural	A	ARL15
5	53535544	rs12233919	A	G	rs12233919	24962325	4.69E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs12233919-A	Research Support, N.I.H., Extramural	A	ARL15
5	53536998	rs9292042	C	T	rs9292042	24962325	4.69E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9292042-C	Research Support, N.I.H., Extramural	T	ARL15
5	53537154	rs10044346	C	T	rs10044346	24962325	4.69E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10044346-C	Research Support, N.I.H., Extramural	T	ARL15
5	53537546	rs2407405	C	T	rs2407405	24962325	4.69E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2407405-C	Research Support, N.I.H., Extramural	C	ARL15
5	53537599	rs250378	G	T	rs250378	24962325	9.95E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs250378-G	Research Support, N.I.H., Extramural	T	ARL15
5	53537742	rs3797237	G	A	rs3797237	24962325	3.30E-06	NA	1.32	[1.20-1.44]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs3797237-G	Research Support, N.I.H., Extramural	C	ARL15
5	53540925	rs166093	G	A	rs166093	24962325	2.90E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs166093-G	Research Support, N.I.H., Extramural	A	ARL15
5	53541553	rs6872062	G	A	rs6872062	24962325	7.83E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6872062-G	Research Support, N.I.H., Extramural	G	ARL15
5	53541755	rs6872430	G	A	rs6872430	24962325	7.83E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6872430-G	Research Support, N.I.H., Extramural	A	ARL15
5	53543905	rs3857282	G	C	rs3857282	24962325	2.60E-06	NA	1.33	[1.21-1.45]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs3857282-G	Research Support, N.I.H., Extramural	G	ARL15
5	53557538	rs388337	C	T	rs388337	24962325	5.90E-06	NA	1.32	[1.20-1.44]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs388337-C	Research Support, N.I.H., Extramural	A	ARL15
5	53565054	rs200457189	GAATAA	G	rs41151	24962325	5.06E-07	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs41151-G	Research Support, N.I.H., Extramural	T	ARL15
5	53565054	rs41151	G	A,C,T	rs41151	24962325	5.06E-07	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs41151-G	Research Support, N.I.H., Extramural	T	ARL15
5	53575691	rs10940373	A	G	rs10940373	24962325	1.60E-06	NA	1.37	[1.23-1.51]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10940373-A	Research Support, N.I.H., Extramural	G	ARL15
5	53582226	rs3776642	T	G	rs3776642	24962325	5.52E-07	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs3776642-T	Research Support, N.I.H., Extramural	A	ARL15
5	53582252	rs3776641	C	T	rs3776641	24962325	9.42E-07	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs3776641-C	Research Support, N.I.H., Extramural	A	ARL15
5	53582400	rs7725454	A	T	rs7725454	24962325	9.42E-07	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7725454-A	Research Support, N.I.H., Extramural	A	ARL15
5	53582505	rs6450184	G	C	rs6450184	24962325	9.42E-07	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6450184-G	Research Support, N.I.H., Extramural	C	ARL15
5	53587702	rs7704911	C	T	rs7704911	24962325	9.88E-06	NA	1.32	[1.20-1.44]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7704911-C	Research Support, N.I.H., Extramural	C	ARL15
5	53592163	rs35952	C	T	rs35952	24962325	2.21E-08	NA	1.42	[1.30-1.54]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs35952-C	Research Support, N.I.H., Extramural	T	ARL15
5	53592361	rs35951	G	T	rs35951	24962325	1.00E-08	NA	1.43	[1.31-1.55]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs35951-G	Research Support, N.I.H., Extramural	T	ARL15
5	53711122	rs7731258	G	A	rs7731258	20201924	5.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	55010963	rs7707639	G	A	rs7707639	20201924	5.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	55567581	rs27006	G	A	rs27006	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	55995035	rs16886113	T	G	rs16886113	20201924	1.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	55995035	rs16886113	T	G	rs16886113	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	56168712	rs2229882	C	T	rs2229882	20201924	3.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	56168712	rs2229882	C	T	rs2229882	20201924	5.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	57786543	rs6895889	G	T	rs6895889	20201924	5.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	60929982	rs26913	C	T	rs26913	21314694	4.99E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	62554047	rs349497	A	C	rs349497	20201924	3.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	62586301	rs7445832	T	A	rs7445832	20202923	2.26E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	62586301	rs7445832	T	A	rs7445832	21703634	3.04E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	62586301	rs7445832	T	A	rs7445832	21956439	4.20E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	63026219	rs12515008	A	G	rs12515008	21703634	8.30E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	64949594	rs17241135	G	A	rs17241135	21314694	9.63E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	65532167	rs10940057	A	G	rs10940057	21314694	1.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	65583098	rs12522102	A	G	rs12522102	20201924	8.53E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	66324075	rs6866391	A	G	rs6866391	20201924	3.79E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	66936150	rs4078050	G	A	rs4078050	24277619	4.94E-04	NA	0.43	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
5	67010538	rs4607305	T	C	rs4607305	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	67751221	rs42905	A	C	rs42905	20201924	5.33E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	73428043	rs288864	A	G	rs288864	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	73506784	rs292203	C	T	rs292203	20201924	6.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	73786880	rs6874566	T	C	rs6874566	24277619	8.74E-04	NA	0.48	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
5	75781290	rs10942782	T	C	rs10942782	20201924	2.82E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	79098186	rs746486	G	A	rs746486	21314694	3.35E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	80109258	rs2306371	T	C	rs2306371	20201924	1.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	80109258	rs2306371	T	C	rs2306371	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	80121646	rs6151896	G	T	rs6151896	20201924	1.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	80121646	rs6151896	G	T	rs6151896	20201924	6.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	80123311	rs3797898	C	T	rs3797898	20201924	1.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	80123311	rs3797898	C	T	rs3797898	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	80130712	rs6874652	C	T	rs6874652	20201924	1.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	80130712	rs6874652	C	T	rs6874652	20201924	6.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	80382806	rs7733625	G	T	rs7733625	19581569	4.22E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
5	83021826	rs1563551	A	G	rs1563551	20201924	4.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	83161278	rs6885336	G	A	rs6885336	21314694	6.96E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	83469915	rs153248	T	C	rs153248	20201924	6.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	85943936	rs7733888	T	C	rs7733888	20201924	2.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	86177591	rs7727185	A	G	rs7727185	21529783	1.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	86339887	rs2410729	G	A	rs2410729	21529783	4.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
5	86350878	rs7715840	A	C	rs7715840	21529783	4.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	86374758	rs2544689	C	T	rs2544689	21529783	6.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	86410998	rs1004988	T	G	rs1004988	21529783	3.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	86450305	rs2032793	G	A	rs2032793	21529783	7.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	86633973	rs3752862	G	A	rs3752862	21314694	8.51E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	88009593	rs254778	G	A	rs254778	21314694	8.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	91039040	rs12516181	T	C	rs12516181	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	91039040	rs12516181	T	C	rs12516181	20201924	1.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	91055657	rs6881283	C	T	rs6881283	20201924	1.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	91055657	rs6881283	C	T	rs6881283	20201924	5.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	91055657	rs6881283	C	T	rs6881283	pha002892	5.58E-05	phs000125	1.51	[1.24-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
5	91130565	rs10057238	A	G	rs10057238	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	91144564	rs16870132	T	C	rs16870132	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	91161330	rs7722750	G	T	rs7722750	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	96071194	rs13362120	T	C	rs13362120	19581569	9.65E-06	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
5	96111371	rs13160562	G	A	rs13160562	19581569	7.00E-06	NA	1.27	[1.14-1.41]	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs13160562-G	Multicenter Study	Research Support, Non-U.S. Gov't	G
5	98087319	rs10900866	T	C	rs10900866	19581569	8.51E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
5	100128913	rs4703116	T	C	rs4703116	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	105117603	rs1482912	C	T	rs1482912	20201924	6.03E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	105405167	rs1404170	T	C	rs1404170	19581569	7.92E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
5	107138981	rs6891749	G	A	rs6891749	21314694	7.14E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	107233791	rs10069340	G	A	rs10069340	21314694	9.76E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	108524616	rs4365877	G	A	rs4365877	20201924	6.85E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	108843934	rs7448843	A	C	rs7448843	24277619	6.41E-04	NA	0.39	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
5	108930590	rs17161951	C	T	rs17161951	24277619	1.14E-04	NA	0.44	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
5	111040322	rs42283	G	A	rs42283	24277619	5.78E-04	NA	0.55	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	LOC100505678
5	113166137	rs1116657	T	C	rs1116657	20201924	7.77E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	115349375	rs1529442	C	T	rs1529442	21314694	9.41E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	115861632	rs154576	G	A	rs154576	21956439	7.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	118953519	rs184497	T	C	rs184497	pha002893	6.86E-05	phs000125	1.51	[1.23-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
5	119869763	rs300974	G	A	rs300974	21314694	8.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	120776767	rs10065963	C	T	rs10065963	20201924	5.56E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	120779886	rs10463741	A	G	rs10463741	20201924	8.47E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	120779886	rs10463741	A	G	rs10463741	pha002891	8.47E-05	phs000125	4	[2.00-7.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
5	120790528	rs1469447	C	A	rs1469447	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	120797151	rs10213966	A	G	rs10213966	20201924	7.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	121190450	rs17148568	A	C	rs17148568	21314694	3.74E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	121570617	rs13356385	G	A	rs13356385	21314694	8.85E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	123398098	rs7448080	T	C	rs7448080	24962325	4.00E-06	NA	1.69	[1.47-1.91]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7448080-T	Research Support, N.I.H., Extramural	C	NA
5	123888331	rs10061885	C	T	rs10061885	20201924	1.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	123889581	rs9327332	A	C	rs9327332	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	125758373	rs4388209	T	C	rs4388209	20201924	4.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	131656760	rs11739484	A	G	rs11739484	20201924	4.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	131723065	rs17689550	C	T	rs17689550	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	133224088	rs731590	C	T	rs731590	21314694	3.27E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	133840796	rs10079478	T	C	rs10079478	21314694	9.11E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	134190225	rs7717860	C	A	rs7717860	21529783	9.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	134663097	rs7712997	G	T	rs7712997	20201924	7.15E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	134929690	rs17168703	A	G	rs17168703	21314694	5.58E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	134930005	rs17168705	C	A	rs17168705	21314694	4.10E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	135377349	rs2107331	C	A	rs2107331	20201924	3.24E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	141479065	rs11167764	A	C	rs11167764	20201924	2.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	141488792	rs9324865	T	C	rs9324865	20201924	1.15E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	141490587	rs4912622	G	A	rs4912622	20201924	4.85E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	141500436	rs11749731	A	C	rs11749731	20201924	8.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	141513204	rs6863411	A	T	rs6863411	20201924	6.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	141513854	rs7709361	T	C	rs7709361	20201924	6.08E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	141515564	rs7733850	C	T	rs7733850	20201924	5.37E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	141523000	rs1062158	C	T	rs1062158	20201924	5.37E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	146229102	rs10037107	A	G	rs10037107	21314694	1.70E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	146320823	rs1864982	G	T	rs1864982	19581569	3.00E-06	NA	1.36	[1.20-1.55]	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs1864982-A	Multicenter Study	Research Support, Non-U.S. Gov't	C
5	146791756	rs11167990	A	G	rs11167990	21314694	7.19E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	147241726	rs10515595	C	T	rs10515595	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	147537156	rs1117507	A	G	rs1117507	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	147541163	rs10037701	C	T	rs10037701	20201924	7.15E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	149136632	rs4705088	T	G	rs4705088	21314694	2.01E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	149137624	rs4705371	C	A	rs4705371	20201924	5.46E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	149154835	rs880770	G	A	rs880770	21314694	7.39E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	150619002	rs168700	G	A	rs168700	20201924	8.05E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	152961624	rs1973372	C	T	rs1973372	21314694	9.18E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	153120048	rs4273649	A	G	rs4273649	21529783	8.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
5	153123455	rs6889794	A	G	rs6889794	21529783	5.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A,G
5	153128715	rs4128572	A	G	rs4128572	21529783	7.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
5	153136785	rs7445323	T	G	rs7445323	21529783	9.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
5	153177053	rs2963998	C	T	rs2963998	21529783	7.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	153573938	rs890793	C	T	rs890793	23089632	1.10E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	155066776	rs4585515	G	A	rs4585515	20201924	3.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	156288822	rs17053982	G	A	rs17053982	21314694	7.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	158096651	rs403334	T	G	rs403334	20201924	7.13E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	158462476	rs13174549	C	T	rs13174549	20201924	6.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	158541200	rs6897374	C	A	rs6897374	24277619	3.69E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
5	158650814	rs7721001	C	T	rs7721001	24277619	6.76E-04	NA	0.43	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
5	158755845	rs1433048	G	A	rs1433048	21703634	2.41E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	162060365	rs312312	A	G	rs312312	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	169477011	rs1316638	T	C	rs1316638	21314694	2.66E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	169923903	rs888936	C	T	rs888936	21529783	5.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	170007503	rs11134638	A	G	rs11134638	20201924	4.59E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	170253981	rs1808374	C	T	rs1808374	20201924	4.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	170253981	rs1808374	C	T	rs1808374	20201924	7.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	171971486	rs1541918	C	A	rs1541918	21529783	1.10E-06	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	172291249	rs13176814	A	G	rs13176814	20201924	6.39E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	173006447	rs10077254	C	T	rs10077254	24277619	5.58E-04	NA	0.59	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
5	173011353	rs746215	T	C	rs746215	24277619	9.05E-04	NA	0.64	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
5	173017087	rs1363605	C	T	rs1363605	21956439	6.80E-05	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
5	174375709	rs17064145	C	A	rs17064145	21703634	8.04E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	174379564	rs4868468	G	A	rs4868468	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	175143632	rs718907	C	A	rs718907	20201924	3.78E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	175764368	rs13169783	T	C	rs13169783	20201924	3.54E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	175764368	rs13169783	T	C	rs13169783	pha002891	3.54E-05	phs000125	1.96	[1.43-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	C5orf25	intron	NM_198567
5	175770421	rs11134972	G	A	rs11134972	20201924	1.63E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	175770421	rs11134972	G	A	rs11134972	pha002891	1.63E-05	phs000125	2.04	[1.47-2.81]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	C5orf25	intron	NM_198567
5	175770422	rs11134973	C	T	rs11134973	20201924	2.29E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	175770422	rs11134973	C	T	rs11134973	pha002891	2.29E-05	phs000125	2	[1.45-2.76]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	C5orf25	intron	NM_198567
5	175776155	rs3749804	A	G	rs3749804	20201924	3.54E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	175776155	rs3749804	A	G	rs3749804	pha002891	3.54E-05	phs000125	1.96	[1.43-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	KIAA1191	intron	NM_020444
5	175781959	rs11134974	C	T	rs11134974	20201924	4.26E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	175781959	rs11134974	C	T	rs11134974	pha002891	4.26E-05	phs000125	1.95	[1.42-2.68]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	KIAA1191	intron	NM_020444
5	175784920	rs10063877	T	C	rs10063877	20201924	3.75E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	175784920	rs10063877	T	C	rs10063877	pha002891	3.75E-05	phs000125	1.96	[1.42-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	KIAA1191	intron	NM_020444
5	175795666	rs13170785	G	A	rs13170785	20201924	5.84E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	177611648	rs9329136	G	A	rs9329136	21703634	5.91E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	177612034	rs7380658	G	T	rs7380658	21703634	4.85E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	177612293	rs7719717	T	G	rs7719717	21703634	6.47E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	177612634	rs7715618	A	C	rs7715618	21703634	6.55E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	177613544	rs2961663	C	T	rs2961663	21703634	9.83E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	177684022	rs2913848	C	T	rs2913848	20201924	7.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
5	178720968	rs166031	A	G	rs166031	24277619	5.44E-04	NA	0.46	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	ADAMTS2
5	180111144	rs2387207	C	T	rs2387207	pha002893	4.50E-05	phs000125	1.49	[1.23-1.82]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
6	1764324	rs3800043	C	T	rs3800043	21703634	6.93E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
6	1918572	rs4463305	T	C	rs4463305	21314694	3.19E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	2524946	rs7749514	C	T	rs7749514	21314694	7.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	5513491	rs9328308	T	C	rs9328308	20201924	6.60E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	5513491	rs9328308	T	C	rs9328308	20201924	7.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	5513491	rs9328308	T	C	rs9328308	pha002893	6.57E-05	phs000125	1.59	[1.27-2.00]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	FARS2	intron	NM_006567
6	5648087	rs10484314	A	G	rs10484314	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	7063271	rs6936076	G	A	rs6936076	21314694	4.61E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	7195009	rs9392863	G	A	rs9392863	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	9314354	rs7772742	G	A	rs7772742	20201924	7.45E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	9608887	rs855250	A	C	rs855250	21703634	9.94E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
6	10460560	rs470790	T	C	rs470790	20201924	7.75E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	10906256	rs4713039	A	G	rs4713039	21314694	1.85E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	11229497	rs9366751	A	G	rs9366751	21314694	9.31E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	11510858	rs6927244	G	A	rs6927244	21314694	4.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	12048827	rs1570989	A	G	rs1570989	20201924	7.61E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	12531551	rs2504899	G	T	rs2504899	21703634	9.80E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
6	15537325	rs10456773	T	C	rs10456773	21314694	9.54E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	16918550	rs1473730	T	C	rs1473730	19581569	9.91E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
6	19214889	rs1858504	C	T	rs1858504	19581569	7.67E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
6	19821781	rs12527834	A	G	rs12527834	19581569	8.24E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
6	19899405	rs9350195	T	C	rs9350195	21314694	7.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	20015205	rs11753077	T	G	rs11753077	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	20027638	rs662751	A	G	rs662751	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	20128557	rs2483767	A	G	rs2483767	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	21824394	rs2479808	C	T	rs2479808	20201924	4.95E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	22686841	rs2057019	C	T	rs2057019	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	23934445	rs518587	A	G	rs518587	20201924	8.95E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	29672686	rs2394660	A	G	rs2394660	20201924	8.46E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	29673483	rs3131863	G	A	rs3131863	20201924	8.45E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	29674741	rs1476572	G	T	rs1476572	20201924	5.89E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	29677877	rs1736931	A	T	rs1736931	20201924	7.36E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	29679047	rs1610594	C	T	rs1610594	20201924	6.13E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	29680021	rs1611371	C	T	rs1611371	20201924	3.52E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	30692768	rs11546742	C	G	rs11546742	20201924	1.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	30692768	rs11546742	C	G	rs11546742	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	30907335	rs3131921	T	C	rs3131921	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	30919391	rs3094086	G	A	rs3094086	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	30920124	rs3132580	G	A	rs3132580	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31922254	rs630379	A	C	rs630379	20201924	2.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31922254	rs630379	A	C	rs630379	20201924	6.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31928799	rs419788	T	C	rs419788	20201924	3.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31929014	rs437179	A	C	rs437179	20201924	3.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31936668	rs410851	T	C	rs410851	20201924	1.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31936668	rs410851	T	C	rs410851	20201924	5.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31946837	rs386480	C	G	rs386480	20201924	1.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31946837	rs386480	C	G	rs386480	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31947460	rs389883	G	T	rs389883	20201924	1.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	31947460	rs389883	G	T	rs389883	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	32033007	rs7766862	G	A	rs7766862	21529783	3.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	32062687	rs2071293	G	A	rs2071293	21529783	5.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	32152387	rs1800624	A	T	rs1800624	21529783	5.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	32788707	rs2621323	A	G	rs2621323	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	32791299	rs2857103	C	A	rs2857103	20201924	8.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	33903076	rs9380389	A	G	rs9380389	21314694	8.13E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	34851134	rs2273006	T	C	rs2273006	21529783	3.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	34904488	rs1737727	T	C	rs1737727	21529783	5.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	34904584	rs847851	G	A	rs847851	21529783	9.30E-06	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	34906168	rs847848	T	C	rs847848	21529783	1.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	34975415	rs2140418	T	C	rs2140418	21529783	4.00E-06	NA	0.1	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol use disorder factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D019973	Alcohol-Related Disorders	NA	NA	Drug abuse	rs2140418-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	36618821	rs1321313	C	T	rs1321313	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	36618821	rs1321313	C	T	rs1321313	20201924	6.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	36622900	rs1321311	C	A	rs1321311	20201924	6.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	36622900	rs1321311	C	A	rs1321311	20201924	7.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	36735480	rs7769970	C	G	rs7769970	21314694	1.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	36934244	rs708006	C	A	rs708006	19581569	1.09E-06	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
6	37301117	rs195411	A	G	rs195411	21314694	3.73E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	37469537	rs2646937	C	T	rs2646937	21314694	4.36E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	37562703	rs6458004	T	C	rs6458004	20201924	8.29E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	37937302	rs6901928	T	C	rs6901928	20201924	9.73E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	37937302	rs6901928	T	C	rs6901928	pha002891	9.73E-05	phs000125	2.56	[1.61-4.17]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	ZFAND3	intron	NM_021943
6	38519761	rs2814889	C	T	rs2814889	21314694	8.21E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	38877605	rs4714198	C	A	rs4714198	21314694	6.65E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	39414027	rs4236064	G	T	rs4236064	21529783	4.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	40365601	rs2436728	G	A	rs2436728	21529783	3.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	41307594	rs6929418	A	G	rs6929418	21314694	3.15E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	41625429	rs2746183	A	C	rs2746183	20201924	5.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	41625429	rs2746183	A	C	rs2746183	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	44533311	rs6923772	A	G	rs6923772	20201924	8.17E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	45391943	rs1321075	T	G	rs1321075	21529783	9.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	46625635	rs10807344	C	T	rs10807344	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	46654246	rs11961117	G	A	rs11961117	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	46669936	rs12528857	C	A	rs12528857	20201924	5.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	46689529	rs3799861	T	C	rs3799861	24277619	7.49E-04	NA	0.58	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	PLA2G7
6	47318818	rs3905310	G	A	rs3905310	21314694	4.96E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	48858479	rs1938218	T	C	rs1938218	20201924	8.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	48862878	rs9357585	G	A	rs9357585	20201924	6.89E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	48949938	rs9367338	C	T	rs9367338	20201924	2.39E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	48957842	rs7772532	T	G	rs7772532	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	52802244	rs371403	A	G	rs371403	21314694	7.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	53143554	rs2281274	T	C	rs2281274	20201924	3.10E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	53143554	rs2281274	T	C	rs2281274	pha002892	3.14E-05	phs000125	1.56	[1.27-1.93]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	ELOVL5	intron	NM_021814
6	53461965	rs2179545	T	C	rs2179545	20201924	4.73E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	64162953	rs9449291	G	A	rs9449291	22096494	7.80E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64176447	rs6942342	T	C	rs6942342	22096494	4.10E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64186032	rs9353016	G	A	rs9353016	22096494	1.00E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64190446	rs4299811	C	T	rs4299811	22096494	7.00E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64190547	rs4557499	G	T	rs4557499	22096494	1.00E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64193107	rs2758259	C	T	rs2758259	22096494	1.10E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64212831	rs1744140	T	C	rs1744140	22096494	1.20E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64215163	rs2984458	T	C	rs2984458	22096494	1.10E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64223145	rs1681957	T	C	rs1681957	22096494	9.10E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64235006	rs1197905	T	C	rs1197905	22096494	9.10E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64254019	rs1322416	T	G	rs1322416	22096494	7.50E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64337297	rs9294269	A	C	rs9294269	22096494	3.70E-06	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64386060	rs10485358	C	T	rs10485358	22096494	3.20E-04	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64397853	rs10755432	A	C	rs10755432	22096494	3.40E-04	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64487247	rs319924	A	G	rs319924	22096494	6.40E-04	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64504252	rs319920	A	G	rs319920	22096494	2.90E-04	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64505213	rs756274	A	G	rs756274	22096494	5.00E-04	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64524151	rs6921058	G	T	rs6921058	22096494	8.00E-04	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
6	64831120	rs3003672	A	C	rs3003672	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	65496953	rs6911837	G	A	rs6911837	20201924	1.99E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	67054884	rs851860	A	G	rs851860	24277619	4.94E-04	NA	1.15	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
6	67803212	rs9351629	G	A	rs9351629	20201924	6.10E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	67803212	rs9351629	G	A	rs9351629	pha002892	6.08E-05	phs000125	1.41	[1.19-1.68]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
6	73660234	rs885247	T	C	rs885247	23089632	1.99E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	73719982	rs10943075	A	G	rs10943075	23089632	7.93E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	73889797	rs12662682	A	G	rs12662682	21314694	2.81E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	74858456	rs7775575	C	T	rs7775575	21529783	3.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	77529907	rs936498	G	A	rs936498	20201924	2.46E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	78160933	rs1343485	A	C	rs1343485	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	79910318	rs9352704	T	C	rs9352704	21314694	9.96E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	80311361	rs1394289	T	C	rs1394289	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80441913	rs9352760	G	A	rs9352760	24277619	2.26E-04	NA	0.96	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
6	80810013	rs7453746	T	G	rs7453746	20201924	7.10E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80810013	rs7453746	T	G	rs7453746	20201924	7.90E-06	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80810013	rs7453746	T	G	rs7453746	pha002892	7.12E-05	phs000125	1.42	[1.19-1.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
6	80810013	rs7453746	T	G	rs7453746	pha002893	7.86E-06	phs000125	1.59	[1.30-1.95]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
6	80816296	rs2298307	T	C	rs2298307	20201924	1.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80816296	rs2298307	T	C	rs2298307	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80828592	rs4437429	A	G	rs4437429	20201924	1.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80828592	rs4437429	A	G	rs4437429	20201924	4.30E-06	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80828592	rs4437429	A	G	rs4437429	pha002892	1.00E-05	phs000125	1.48	[1.24-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	BCKDHB	intron	NM_183050
6	80828592	rs4437429	A	G	rs4437429	pha002893	4.34E-06	phs000125	1.61	[1.31-1.97]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	BCKDHB	intron	NM_183050
6	80837253	rs9448894	G	A,C,T	rs9448894	20201924	7.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80837253	rs9448894	G	A,C,T	rs9448894	20201924	7.30E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80837253	rs9448894	G	A,C,T	rs9448894	pha002892	7.28E-05	phs000125	1.41	[1.19-1.68]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	BCKDHB	intron	NM_183050
6	80837253	rs9448894	G	A,C,T	rs9448894	pha002893	7.14E-05	phs000125	1.5	[1.23-1.84]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	BCKDHB	intron	NM_183050
6	80839315	rs4706113	C	T	rs4706113	20201924	7.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80839315	rs4706113	C	T	rs4706113	20201924	7.30E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80839315	rs4706113	C	T	rs4706113	pha002892	7.28E-05	phs000125	1.41	[1.19-1.68]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	BCKDHB	intron	NM_183050
6	80839315	rs4706113	C	T	rs4706113	pha002893	7.14E-05	phs000125	1.5	[1.23-1.84]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	BCKDHB	intron	NM_183050
6	80843956	rs2322631	A	C	rs2322631	20201924	4.10E-06	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80843956	rs2322631	A	C	rs2322631	20201924	9.70E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80843956	rs2322631	A	C	rs2322631	pha002892	9.67E-06	phs000125	1.48	[1.24-1.76]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	BCKDHB	intron	NM_183050
6	80843956	rs2322631	A	C	rs2322631	pha002893	4.13E-06	phs000125	1.61	[1.31-1.97]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	BCKDHB	intron	NM_183050
6	80845989	rs2322633	T	C	rs2322633	20201924	1.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80845989	rs2322633	T	C	rs2322633	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80854470	rs10080237	T	C	rs10080237	20201924	4.10E-06	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80854470	rs10080237	T	C	rs10080237	20201924	9.70E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80854470	rs10080237	T	C	rs10080237	pha002892	9.67E-06	phs000125	1.48	[1.24-1.76]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	BCKDHB	intron	NM_183050
6	80854470	rs10080237	T	C	rs10080237	pha002893	4.13E-06	phs000125	1.61	[1.31-1.97]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	BCKDHB	intron	NM_183050
6	80880150	rs942381	T	G	rs942381	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80880150	rs942381	T	G	rs942381	20201924	1.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80924645	rs9343974	A	G	rs9343974	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80924645	rs9343974	A	G	rs9343974	20201924	1.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80959912	rs978814	C	A	rs978814	20201924	1.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80959912	rs978814	C	A	rs978814	20201924	3.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80959912	rs978814	C	A	rs978814	pha002892	3.03E-05	phs000125	1.44	[1.21-1.71]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	BCKDHB	intron	NM_183050
6	80959912	rs978814	C	A	rs978814	pha002893	1.91E-05	phs000125	1.55	[1.27-1.90]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	BCKDHB	intron	NM_183050
6	80967001	rs9343977	C	T	rs9343977	20201924	2.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80967001	rs9343977	C	T	rs9343977	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80968727	rs3812121	A	G	rs3812121	20201924	2.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80968727	rs3812121	A	G	rs3812121	20201924	4.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80968727	rs3812121	A	G	rs3812121	pha002892	4.03E-05	phs000125	1.43	[1.21-1.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	BCKDHB	intron	NM_183050
6	80968727	rs3812121	A	G	rs3812121	pha002893	2.07E-05	phs000125	1.55	[1.27-1.90]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	BCKDHB	intron	NM_183050
6	80979053	rs2179842	T	C	rs2179842	20201924	2.60E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80979053	rs2179842	T	C	rs2179842	20201924	3.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	80979053	rs2179842	T	C	rs2179842	pha002892	3.51E-05	phs000125	1.44	[1.21-1.71]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	BCKDHB	intron	NM_183050
6	80979053	rs2179842	T	C	rs2179842	pha002893	2.61E-05	phs000125	1.54	[1.26-1.89]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	BCKDHB	intron	NM_183050
6	81012605	rs4706834	G	T	rs4706834	20201924	1.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	81012605	rs4706834	G	T	rs4706834	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	81025879	rs9352817	T	G	rs9352817	20201924	8.20E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	81025879	rs9352817	T	G	rs9352817	20201924	8.90E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	81025879	rs9352817	T	G	rs9352817	pha002892	8.91E-05	phs000125	1.4	[1.19-1.66]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	BCKDHB	intron	NM_183050
6	81025879	rs9352817	T	G	rs9352817	pha002893	8.23E-05	phs000125	1.49	[1.22-1.82]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	BCKDHB	intron	NM_183050
6	81040867	rs10455370	C	T	rs10455370	20201924	7.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	82828838	rs9443958	C	T	rs9443958	21314694	9.77E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	85800720	rs9450148	A	G	rs9450148	20201924	1.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	85934442	rs13206561	G	A	rs13206561	20201924	4.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	86028681	rs11752804	G	A	rs11752804	20201924	1.30E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	86028681	rs11752804	G	A	rs11752804	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	86028681	rs11752804	G	A	rs11752804	pha002892	1.30E-05	phs000125	1.9	[1.42-2.53]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
6	86885509	rs220394	G	A	rs220394	24277619	6.85E-04	NA	1.21	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
6	87001570	rs17541873	G	A	rs17541873	24277619	4.31E-04	NA	1	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
6	87094486	rs12193553	G	T	rs12193553	24277619	9.30E-05	NA	4.86	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
6	89977906	rs4707535	T	C	rs4707535	20201924	6.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	89977906	rs4707535	T	C	rs4707535	pha002892	5.97E-05	phs000125	1.52	[1.23-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	GABRR2	intron	NM_002043
6	90405993	rs9362672	C	G	rs9362672	21314694	7.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	93674832	rs17437983	T	C	rs17437983	19581569	5.75E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
6	94112802	rs625822	C	T	rs625822	20201924	4.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	94112802	rs625822	C	T	rs625822	20201924	7.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	94112802	rs625822	C	T	rs625822	pha002892	7.50E-05	phs000125	1.49	[1.22-1.82]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	EPHA7	intron	NM_004440
6	94389460	rs13208357	C	T	rs13208357	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	94473157	rs7765319	C	T	rs7765319	20201924	6.82E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	96595020	rs4132260	C	T	rs4132260	23089632	1.12E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	96739393	rs2263190	T	C	rs2263190	23089632	6.78E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	97314345	rs9374164	T	C	rs9374164	21314694	2.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	100779692	rs9390276	T	C	rs9390276	24277619	7.09E-04	NA	0.43	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
6	103775306	rs7768059	G	T	rs7768059	21529783	8.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	107886522	rs7775895	G	A	rs7775895	21529783	5.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	108175173	rs632582	G	A	rs632582	21314694	9.74E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	110231998	rs4245542	T	C	rs4245542	20201924	1.13E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	112964352	rs9387092	C	T	rs9387092	24277619	1.11E-04	NA	0.45	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
6	114378970	rs2282237	C	T	rs2282237	21314694	1.35E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	119570101	rs17080911	C	A	rs17080911	20201924	3.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	120452629	rs12661222	A	G	rs12661222	20201924	8.88E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	120484779	rs17081960	C	T	rs17081960	20201924	4.25E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	120484779	rs17081960	C	T	rs17081960	pha002891	4.25E-05	phs000125	2.63	[1.64-4.17]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
6	120490336	rs155155	A	G	rs155155	20201924	8.32E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	120490336	rs155155	A	G	rs155155	pha002891	8.32E-05	phs000125	1.47	[0.90-2.40]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
6	123983066	rs979537	T	C	rs979537	21529783	6.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	125401564	rs571846	C	T	rs571846	21314694	6.68E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	125666821	rs1934990	C	A	rs1934990	21703634	6.54E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
6	127850966	rs1512454	G	A	rs1512454	21314694	8.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	128951307	rs17056140	T	C	rs17056140	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	129373689	rs4534007	G	A	rs4534007	19581569	7.23E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
6	129384367	rs4895846	T	C	rs4895846	19581569	8.71E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
6	129798084	rs2571577	T	C	rs2571577	21314694	7.05E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	130032745	rs12213388	T	C	rs12213388	20201924	3.32E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	130154667	rs9492393	T	C	rs9492393	20201924	1.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	130154667	rs9492393	T	C	rs9492393	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	130155713	rs6912805	T	C	rs6912805	20201924	1.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	130155713	rs6912805	T	C	rs6912805	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	130806316	rs12210827	A	T	rs12210827	21314694	8.40E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	130984945	rs2020202	T	C	rs2020202	20201924	2.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	131090112	rs17059529	G	A	rs17059529	21314694	5.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	132600984	rs1883339	G	A	rs1883339	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	132607038	rs2092236	A	G	rs2092236	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	132607796	rs11760080	G	A	rs11760080	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	132613798	rs17061146	C	T	rs17061146	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	132617469	rs6903616	C	T	rs6903616	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	132817897	rs2842891	C	T	rs2842891	21314694	2.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	135148949	rs6904528	A	T	rs6904528	21314694	2.34E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	136370658	rs6921041	T	G	rs6921041	24277619	3.62E-04	NA	0.45	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	PDE7B
6	136396874	rs7765567	A	G	rs7765567	24277619	4.49E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	PDE7B
6	137324655	rs1744061	C	T	rs1744061	24277619	5.14E-04	NA	0.67	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	IL20RA
6	138417080	rs2506843	C	G	rs2506843	21314694	3.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	138417118	rs2484066	T	G	rs2484066	24277619	1.50E-05	NA	1.54	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	PERP
6	139216426	rs10499204	T	C	rs10499204	21314694	5.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	139238599	rs2272432	G	T	rs2272432	21314694	2.72E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	143145232	rs7768492	T	G	rs7768492	20201924	7.84E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	143270216	rs2095369	A	G	rs2095369	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	143270216	rs2095369	A	G	rs2095369	20201924	5.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	143735762	rs2496590	T	C	rs2496590	21314694	6.41E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	144079788	rs6931825	A	C	rs6931825	24277619	3.31E-04	NA	0.77	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	PHACTR2
6	144683621	rs12664298	G	A	rs12664298	20201924	4.52E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	148045181	rs9322108	A	G	rs9322108	21529783	6.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	148953088	rs6420783	C	A	rs6420783	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	149321746	rs2486396	C	T	rs2486396	21314694	4.94E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	149336009	rs2486416	C	T	rs2486416	21314694	6.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	150239330	rs17079029	C	T	rs17079029	21314694	7.43E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	151163115	rs17427389	G	A	rs17427389	20202923	6.45E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	151163115	rs17427389	G	A	rs17427389	21956439	7.20E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	152157881	rs6902771	C	T	rs6902771	19581569	8.00E-06	NA	1.24	[1.13-1.36]	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs6902771-C	Multicenter Study	Research Support, Non-U.S. Gov't	C
6	154708633	rs12526737	T	C	rs12526737	20201924	5.81E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	156163798	rs9397270	T	C	rs9397270	20201924	7.93E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	156342622	rs1449675	T	C	rs1449675	20201924	1.94E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	156492674	rs9397906	G	A	rs9397906	24277619	9.68E-04	NA	0.45	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
6	158411156	rs9365674	C	T	rs9365674	21703634	9.27E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
6	158480144	rs1750034	A	C	rs1750034	24277619	2.70E-04	NA	0.62	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	SYNJ2
6	161450528	rs9295134	C	T	rs9295134	21956439	7.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	161474966	rs12110787	A	C	rs12110787	21956439	5.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	161495658	rs9355870	A	G	rs9355870	21956439	7.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	161522478	rs9458121	A	G	rs9458121	21529783	2.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	161522478	rs9458121	A	G	rs9458121	21956439	1.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	161565158	rs12191615	T	C	rs12191615	20201924	8.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	164091657	rs1407662	A	G	rs1407662	20201924	2.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
6	164478916	rs395843	T	C	rs395843	21529783	6.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	165849238	rs220821	A	C	rs220821	24277619	9.37E-04	NA	0.38	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	PDE10A
6	165867791	rs9459418	C	A	rs9459418	21314694	3.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	168375191	rs2076663	C	T	rs2076663	21314694	8.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	169811294	rs368028	C	T	rs368028	21314694	9.11E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	170130247	rs9478099	G	C	rs9478099	21314694	8.08E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
6	170516123	rs9348260	G	A	rs9348260	20201924	7.11E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	1950809	rs4332037	C	T	rs4332037	20201924	4.63E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	3093297	rs11768102	C	T	rs11768102	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	4026009	rs11978979	A	T	rs11978979	21314694	1.22E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	5696125	rs852519	C	A,G,T	rs852519	21314694	5.21E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	6314766	rs4724793	T	C	rs4724793	21529783	6.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	6326147	rs12531066	A	G	rs12531066	21314694	2.13E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	7156472	rs6970410	C	T	rs6970410	24277619	1.74E-04	NA	0.45	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
7	7976243	rs7779286	A	G	rs7779286	20201924	7.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	8329762	rs7797010	G	T	rs7797010	24277619	9.17E-04	NA	0.55	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	LOC100505938
7	9010322	rs6959898	A	G	rs6959898	19581569	5.36E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
7	9903357	rs728260	G	A	rs728260	21529783	2.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	9906710	rs2915125	T	C	rs2915125	21529783	2.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
7	9926030	rs2915131	T	C	rs2915131	21529783	2.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
7	9965912	rs1557978	T	C	rs1557978	21529783	7.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	10278806	rs10225194	T	G	rs10225194	20201924	2.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	10452576	rs1111644	T	G	rs1111644	21529783	2.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	10469534	rs765805	C	T	rs765805	21529783	6.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	10990312	rs1681300	G	A	rs1681300	21314694	7.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	11008465	rs12112329	T	C	rs12112329	21314694	9.03E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	11321893	rs10253872	C	T	rs10253872	24277619	7.65E-04	NA	0.4	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
7	11677778	rs2526100	T	C	rs2526100	21314694	4.07E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	12781543	rs17616845	T	C	rs17616845	23089632	8.49E-08	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	14646285	rs17602660	A	T	rs17602660	21314694	3.26E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	17009601	rs1721013	C	T	rs1721013	21314694	8.98E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	17495669	rs1868361	C	T	rs1868361	20201924	5.18E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	19211253	rs11973510	C	A	rs11973510	21314694	8.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	22158064	rs17707505	C	T	rs17707505	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	23832103	rs12666547	C	A	rs12666547	21314694	5.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	28715056	rs16874653	A	G	rs16874653	20201924	5.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	28813782	rs4719953	T	A	rs4719953	21314694	7.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	29130762	rs7776819	A	G	rs7776819	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	29130762	rs7776819	A	G	rs7776819	20201924	2.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	29180335	rs13238274	C	T	rs13238274	21314694	9.04E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	30511949	rs2037955	C	A	rs2037955	21314694	8.75E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	30820930	rs11765514	G	T	rs11765514	21314694	7.51E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	31116168	rs12668955	G	A	rs12668955	20201924	7.88E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	31949763	rs13223209	G	A	rs13223209	21314694	8.59E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	34104225	rs1362456	G	A	rs1362456	19581569	6.36E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
7	34375553	rs1362182	G	A	rs1362182	20201924	8.93E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	37726951	rs1982389	A	G	rs1982389	20201924	2.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	39198864	rs41437948	T	G	rs41437948	21314694	9.77E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	43286839	rs17172185	T	C	rs17172185	pha002893	8.52E-05	phs000125	2.41	[1.56-3.74]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	HECW1	intron	NM_015052
7	43286893	rs17723330	G	A	rs17723330	20201924	6.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	43286893	rs17723330	G	A	rs17723330	pha002893	6.14E-05	phs000125	2.47	[1.59-3.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	HECW1	intron	NM_015052
7	43568104	rs13226386	G	A	rs13226386	21314694	4.22E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	44178743	rs882020	C	T	rs882020	21314694	4.23E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	45906903	rs12667301	G	A	rs12667301	21314694	2.39E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	45908994	rs1553009	G	A	rs1553009	21314694	1.54E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	48928297	rs885685	G	A	rs885685	20201924	1.09E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	50207532	rs12531206	G	A	rs12531206	23089632	5.47E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	50207547	rs10273199	A	C	rs10273199	21314694	1.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	52612271	rs712013	G	A	rs712013	21703634	4.39E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
7	52620633	rs804753	T	C	rs804753	21703634	4.89E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
7	54708056	rs17563093	A	G	rs17563093	20201924	4.75E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	54709473	rs475048	T	A	rs475048	21314694	8.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	55171629	rs2877260	A	G	rs2877260	21529783	4.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	56262054	rs10248609	C	T	rs10248609	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	56291170	rs1357741	G	A	rs1357741	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	67828081	rs1874243	G	A	rs1874243	20201924	7.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	70131823	rs2107942	T	C	rs2107942	21314694	6.17E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	73581402	rs223011	C	T	rs223011	20201924	4.82E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	73583703	rs223002	G	T	rs223002	20201924	1.59E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	75210659	rs237240	C	T	rs237240	21529783	2.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	75211414	rs237238	A	G	rs237238	21529783	7.00E-06	NA	0.16	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (12-month weekly alcohol consumption)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs237238-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	77327333	rs35216166	G	A	rs35216166	24277619	1.02E-04	NA	4.72	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	RSBN1L
7	78104476	rs6466241	T	C	rs6466241	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	78408559	rs13308578	C	T	rs13308578	20201924	4.03E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	78929161	rs1609276	G	C	rs1609276	21314694	9.30E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	80619607	rs853050	C	T	rs853050	21314694	6.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	82017449	rs6975142	A	T	rs6975142	21314694	4.67E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	82968522	rs9690922	A	G	rs9690922	20201924	4.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	82968522	rs9690922	A	G	rs9690922	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	86186533	rs781028	T	C	rs781028	21314694	6.57E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	86348037	rs2237547	A	G	rs2237547	21314694	5.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	87168749	rs4728699	C	T	rs4728699	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	87172053	rs4728701	A	G	rs4728701	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	88580316	rs17165697	G	A	rs17165697	20201924	8.06E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	90782534	rs705362	A	G	rs705362	21314694	5.34E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	90794795	rs803174	G	A	rs803174	21314694	3.26E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	91684086	rs12536529	A	G	rs12536529	21314694	1.54E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	91779971	rs6465353	T	G	rs6465353	21314694	1.70E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	91874686	rs12704637	C	T	rs12704637	21314694	2.08E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	92029302	rs12740	G	A	rs12740	21314694	2.41E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	92077716	rs4729043	G	A	rs4729043	20201924	5.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	92080395	rs2287179	A	G	rs2287179	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	92116101	rs6944759	C	T	rs6944759	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	92131029	rs3213609	A	G	rs3213609	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	92136073	rs7809455	T	C	rs7809455	20201924	5.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	92165862	rs929412	C	T	rs929412	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	92207270	rs6465363	C	T	rs6465363	20201924	9.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	92542849	rs10241695	C	T	rs10241695	21314694	5.61E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	95305368	rs854061	G	A	rs854061	21703634	7.22E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
7	95325734	rs854104	A	G	rs854104	21703634	6.25E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
7	96542982	rs17168021	T	C	rs17168021	24277619	1.35E-04	NA	0.69	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
7	96562031	rs1207688	C	T	rs1207688	24277619	3.10E-05	NA	0.5	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
7	98192191	rs705326	T	C	rs705326	21314694	8.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	103810129	rs2385134	G	A	rs2385134	20201924	7.91E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	103836980	rs10260238	C	T	rs10260238	20201924	6.94E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	103837341	rs6949887	G	A	rs6949887	20201924	5.83E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	104558939	rs2891786	C	T	rs2891786	20201924	8.93E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	105221097	rs1706923	A	G	rs1706923	21314694	5.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	107765230	rs7794978	C	A	rs7794978	21314694	1.67E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	110935979	rs11534045	G	A	rs11534045	21529783	5.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	110949566	rs6962665	C	A	rs6962665	21529783	6.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	112420072	rs7806781	C	T	rs7806781	21529783	6.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	114355002	rs12705988	A	G	rs12705988	21314694	6.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	114658486	rs13237006	A	G	rs13237006	21314694	4.36E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	117621877	rs7777391	A	G	rs7777391	20202923	2.70E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	117621877	rs7777391	A	G	rs7777391	22096494	3.00E-07	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
7	120765954	rs798949	T	C	rs798949	21314694	6.61E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	121275229	rs10253361	C	T	rs10253361	21529783	6.00E-06	NA	0.08	[NA] unit decrease	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol dependence factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs10253361-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
7	121275477	rs10227063	A	G	rs10227063	21529783	5.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	124078609	rs13239910	T	G	rs13239910	21703634	7.54E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
7	126368292	rs10256873	G	A	rs10256873	21314694	9.14E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	128014136	rs1651939	C	A	rs1651939	21314694	6.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	128222966	rs10230965	G	T	rs10230965	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	128568960	rs729302	A	C	rs729302	19581569	4.62E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
7	131223177	rs6953894	A	G	rs6953894	21314694	7.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	131226911	rs7807320	G	T	rs7807320	21314694	1.02E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	131865092	rs896170	T	C	rs896170	20201924	3.09E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	133474772	rs1476118	C	T	rs1476118	20201924	1.25E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	133970444	rs393459	T	G	rs393459	21314694	9.61E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	134465394	rs2347896	C	A	rs2347896	21314694	5.03E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	134994297	rs17235985	G	T	rs17235985	20201924	1.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	137703336	rs11971315	G	A	rs11971315	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	139359087	rs10954654	C	T	rs10954654	21529783	8.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	139496215	rs6958644	A	G	rs6958644	20201924	6.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	140071315	rs7777468	C	T	rs7777468	20201924	6.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	140071315	rs7777468	C	T	rs7777468	pha002892	6.51E-05	phs000125	1.72	[1.32-2.27]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	SLC37A3	intron	NM_032295
7	140077428	rs6955063	A	C	rs6955063	20201924	4.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	140077428	rs6955063	A	C	rs6955063	pha002892	4.02E-05	phs000125	1.75	[1.33-2.27]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	SLC37A3	intron	NM_032295
7	140079848	rs6947516	G	A	rs6947516	20201924	6.30E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	140079848	rs6947516	G	A	rs6947516	pha002892	6.25E-05	phs000125	1.72	[1.33-2.27]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SLC37A3	intron	NM_032295
7	140096157	rs9640465	C	T	rs9640465	20201924	2.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	140096203	rs9640467	C	T	rs9640467	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	142100911	rs7796556	C	T	rs7796556	21529783	5.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	142839168	rs12703516	A	G	rs12703516	20201924	7.12E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	144292762	rs10224675	A	G	rs10224675	21956439	3.80E-05	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	146968295	rs10279700	T	C	rs10279700	21314694	4.08E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	148771346	rs6973937	C	T	rs6973937	20201924	3.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	148778682	rs12113550	A	G	rs12113550	20201924	3.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	148785721	rs7797617	A	C	rs7797617	20201924	3.86E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	150060163	rs10263613	G	A	rs10263613	20201924	8.94E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	151415041	rs10224002	A	G	rs10224002	21314694	7.28E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	151653635	rs10952334	G	C	rs10952334	21314694	7.81E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	154900857	rs2969540	C	T	rs2969540	20201924	4.85E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
7	156042243	rs4446619	G	A	rs4446619	24277619	7.63E-04	NA	0.39	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
7	157277828	rs741000	C	T	rs741000	21314694	7.80E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
7	157819325	rs11772608	T	C	rs11772608	24277619	7.23E-04	NA	0.55	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	PTPRN2
8	531083	rs11136864	A	C	rs11136864	24277619	2.07E-04	NA	0.69	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
8	1648035	rs7825359	A	G	rs7825359	24277619	5.01E-04	NA	0.46	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	DLGAP2
8	1649960	rs7005715	G	A	rs7005715	24277619	4.60E-05	NA	0.51	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	DLGAP2
8	3643255	rs1383951	C	T	rs1383951	20201924	7.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	3682023	rs7830364	A	G	rs7830364	21314694	1.10E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	3947325	rs11783062	T	G	rs11783062	23089632	4.18E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	4070495	rs3849840	C	A,T	rs3849840	24277619	2.27E-04	NA	0.7	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	CSMD1
8	4110032	rs13259289	T	C	rs13259289	23942779	5.30E-04	NA	0.25	[NA] unit decrease	7,188 European ancestry individuals	European(7188)	ALL(7188)	EUR(7188)	ALL(7188)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs13259289-G	Twin Study	Research Support, N.I.H., Extramural	T
8	5579875	rs263328	T	G	rs263328	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	5580761	rs1512791	A	G	rs1512791	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	5581652	rs2725730	A	C	rs2725730	20201924	2.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	5581690	rs2733020	A	C	rs2733020	20201924	2.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	5582174	rs2733022	T	C	rs2733022	20201924	2.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	5584374	rs2527128	C	A	rs2527128	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	5641443	rs7813894	C	T	rs7813894	20201924	1.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	5641443	rs7813894	C	T	rs7813894	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	6612836	rs2980700	G	A	rs2980700	21314694	7.30E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	6633702	rs17637986	T	G	rs17637986	20201924	5.20E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	6633702	rs17637986	T	G	rs17637986	20201924	5.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	6633702	rs17637986	T	G	rs17637986	pha002892	5.45E-05	phs000125	1.79	[1.35-2.38]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
8	6633702	rs17637986	T	G	rs17637986	pha002893	5.17E-05	phs000125	2.04	[1.45-2.86]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
8	6634214	rs2912091	C	T	rs2912091	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	6634214	rs2912091	C	T	rs2912091	20201924	3.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	6634214	rs2912091	C	T	rs2912091	pha002893	3.87E-05	phs000125	1.75	[1.35-2.33]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
8	6634774	rs2912089	G	A	rs2912089	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	6634774	rs2912089	G	A	rs2912089	20201924	3.70E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	6634774	rs2912089	G	A	rs2912089	pha002893	3.72E-05	phs000125	1.79	[1.35-2.33]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
8	6637188	rs17078124	C	T	rs17078124	20201924	6.31E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	8155475	rs2945891	G	A	rs2945891	21314694	1.71E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	8384479	rs11777086	G	T	rs11777086	21529783	8.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
8	9508879	rs4128324	A	G	rs4128324	24277619	9.85E-04	NA	0.42	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	TNKS
8	11294575	rs4310165	C	T	rs4310165	21314694	8.39E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	11643915	rs804292	G	A	rs804292	23942779	2.00E-06	NA	0.41	[NA] unit decrease	7,188 European ancestry individuals	European(7188)	ALL(7188)	EUR(7188)	ALL(7188)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs804292-G	Twin Study	Research Support, N.I.H., Extramural	T
8	11830502	rs9657521	A	C,G,T	rs9657521	24277619	9.41E-04	NA	0.41	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
8	15355669	rs6985300	A	C	rs6985300	20201924	4.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15355669	rs6985300	A	C	rs6985300	20201924	4.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15355669	rs6985300	A	C	rs6985300	pha002893	4.38E-05	phs000125	1.54	[1.25-1.90]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
8	15356034	rs6530877	C	T	rs6530877	20201924	1.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15356034	rs6530877	C	T	rs6530877	20201924	7.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15356384	rs1390052	A	C	rs1390052	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15356384	rs1390052	A	C	rs1390052	20201924	8.00E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15356384	rs1390052	A	C	rs1390052	pha002893	8.02E-05	phs000125	1.52	[1.23-1.87]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
8	15356455	rs1390053	C	T	rs1390053	20201924	4.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15356455	rs1390053	C	T	rs1390053	20201924	7.00E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15356455	rs1390053	C	T	rs1390053	pha002893	7.02E-05	phs000125	1.52	[1.24-1.88]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
8	15356535	rs1390054	C	T	rs1390054	20201924	1.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15356535	rs1390054	C	T	rs1390054	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15357053	rs7013543	C	A	rs7013543	20201924	1.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15357809	rs13271637	G	A	rs13271637	20201924	1.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	15357809	rs13271637	G	A	rs13271637	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	16558730	rs10097146	G	A	rs10097146	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	16575112	rs1580852	C	T	rs1580852	20201924	4.71E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	16830934	rs1721078	A	G	rs1721078	24277619	5.67E-04	NA	0.61	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
8	16837199	rs823583	A	G	rs823583	24277619	9.97E-04	NA	0.59	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
8	16929635	rs10090288	A	C	rs10090288	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	18795045	rs6999315	A	G	rs6999315	20201924	8.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	19511972	rs11779629	A	T	rs11779629	21314694	3.55E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	19600329	rs6983139	A	G	rs6983139	20201924	2.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	19600329	rs6983139	A	G	rs6983139	20201924	5.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	19600329	rs6983139	A	G	rs6983139	pha002892	2.65E-05	phs000125	1.45	[1.22-1.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
8	19600329	rs6983139	A	G	rs6983139	pha002893	5.10E-05	phs000125	1.52	[1.23-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
8	19762732	rs6586879	C	T	rs6586879	21314694	2.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	20639494	rs10089021	T	C	rs10089021	21529783	8.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
8	21793608	rs6996493	A	G	rs6996493	21314694	7.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	23411275	rs17089358	T	C	rs17089358	21314694	6.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	23691273	rs17784945	A	G	rs17784945	20201924	5.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	25834968	rs11984569	G	T	rs11984569	20201924	1.91E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	26227640	rs3808565	A	G	rs3808565	20201924	2.81E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	27512786	rs12677898	A	G	rs12677898	21314694	7.99E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	29873603	rs309853	A	G	rs309853	24277619	3.76E-04	NA	0.44	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
8	29876605	rs9297181	G	A	rs9297181	24277619	3.70E-04	NA	0.45	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
8	32517162	rs2466046	G	A	rs2466046	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	36158771	rs670603	C	T	rs670603	20201924	1.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	39131690	rs7830120	G	A	rs7830120	21314694	9.31E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	40965681	rs6474300	A	G	rs6474300	21703634	4.38E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	40967164	rs12550040	G	T	rs12550040	21703634	4.18E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	40972233	rs12547609	A	C	rs12547609	21703634	3.02E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	40973567	rs12548368	A	G	rs12548368	21703634	5.68E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	40980390	rs737505	C	T	rs737505	20201924	8.82E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	41387921	rs7819949	C	T	rs7819949	20201924	1.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	41387921	rs7819949	C	T	rs7819949	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	49323385	rs6987448	C	T	rs6987448	20201924	6.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	49364880	rs13280598	C	A	rs13280598	20201924	5.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	51613483	rs713179	A	G	rs713179	21314694	5.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	52557431	rs4873568	T	C	rs4873568	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53037349	rs2114226	T	C	rs2114226	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53039720	rs7821217	G	A	rs7821217	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53041190	rs9694119	T	C	rs9694119	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53046681	rs11990195	G	A	rs11990195	20201924	1.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53046681	rs11990195	G	A	rs11990195	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53049037	rs3815868	T	C	rs3815868	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53055483	rs7010548	C	T	rs7010548	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53055483	rs7010548	C	T	rs7010548	20201924	8.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53058501	rs7837915	G	A	rs7837915	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53058501	rs7837915	G	A	rs7837915	20201924	2.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53059486	rs3891723	G	A	rs3891723	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53059486	rs3891723	G	A	rs3891723	20201924	2.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53068920	rs17290977	C	T	rs17290977	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	53758886	rs10112899	G	A	rs10112899	21314694	7.97E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	58514086	rs2325777	C	T	rs2325777	20201924	1.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	58616620	rs7004631	G	A	rs7004631	24277619	3.82E-04	NA	0.43	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
8	58664288	rs9694511	T	C	rs9694511	24277619	7.92E-04	NA	0.4	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
8	58670352	rs10096565	A	C	rs10096565	24277619	4.10E-04	NA	0.44	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
8	60214029	rs6997052	G	A	rs6997052	20201924	7.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	60221132	rs7835993	G	A	rs7835993	20201924	7.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	61764389	rs3763591	G	T	rs3763591	20201924	2.67E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	62839354	rs6981356	T	C	rs6981356	20201924	7.52E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	70442873	rs16936012	G	T	rs16936012	22096494	7.30E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
8	70970618	rs16936661	T	C	rs16936661	21314694	2.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	72684401	rs4738159	C	T	rs4738159	21314694	6.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	73439070	rs1431659	A	G	rs1431659	21314694	3.87E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	75154867	rs17337083	T	C	rs17337083	21314694	5.27E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	76811708	rs3911770	T	G	rs3911770	21529783	6.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
8	78093837	rs7821178	C	A,G,T	rs7821178	20201924	4.94E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	78325636	rs13258743	G	A	rs13258743	20201924	3.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	79186223	rs1030547	G	A	rs1030547	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	79186223	rs1030547	G	A	rs1030547	20201924	7.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	85118619	rs7845564	C	T	rs7845564	21314694	8.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	87761007	rs4961216	A	C	rs4961216	21529783	2.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
8	87934432	rs4526378	G	T	rs4526378	21314694	4.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	88125718	rs719779	T	C	rs719779	20201924	7.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	88255964	rs2336981	G	A	rs2336981	20201924	5.01E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	88255964	rs2336981	G	A	rs2336981	pha002891	5.01E-05	phs000125	2.13	[1.47-3.03]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	CNBD1	intron	NM_173538
8	88261791	rs7833568	T	C	rs7833568	20201924	3.55E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	88261791	rs7833568	T	C	rs7833568	pha002891	3.55E-05	phs000125	2.17	[1.49-3.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	CNBD1	intron	NM_173538
8	88480902	rs428838	T	C	rs428838	20201924	2.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	88480902	rs428838	T	C	rs428838	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	90601100	rs11780016	A	G	rs11780016	19581569	6.09E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
8	91288667	rs4735301	A	G	rs4735301	24277619	2.28E-04	NA	0.43	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
8	93568065	rs2256182	T	C	rs2256182	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	94352802	rs277778	A	G	rs277778	19581569	4.31E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
8	97685591	rs12675345	C	A	rs12675345	20201924	3.18E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	99129649	rs2071597	A	G	rs2071597	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	99133678	rs4734384	A	C	rs4734384	20201924	2.15E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	99137153	rs10808358	G	A	rs10808358	20201924	3.84E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	99139610	rs4735529	C	T	rs4735529	20201924	1.31E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	102609456	rs16867971	T	C	rs16867971	21314694	9.97E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	103714346	rs2513929	C	T	rs2513929	21314694	7.07E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	106269195	rs2880439	A	G	rs2880439	21314694	9.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	109096029	rs374810	G	A	rs374810	20201924	1.58E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	112098293	rs11781492	G	A	rs11781492	20201924	4.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	112098293	rs11781492	G	A	rs11781492	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	113246250	rs4876460	T	C	rs4876460	21314694	9.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	114226643	rs10505201	G	A	rs10505201	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	114274275	rs6996697	A	G	rs6996697	20201924	4.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	116320062	rs6469576	G	A	rs6469576	24277619	7.07E-04	NA	1.11	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
8	117681031	rs7833054	A	G	rs7833054	21314694	4.82E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	117916281	rs720133	T	C	rs720133	20201924	3.20E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	117916281	rs720133	T	C	rs720133	pha002891	3.20E-05	phs000125	2.04	[1.45-2.86]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
8	118808893	rs10113582	T	C	rs10113582	21529783	4.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
8	121650125	rs11780390	G	A	rs11780390	21314694	5.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	121971039	rs7824584	T	C	rs7824584	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	121972058	rs6988609	A	C	rs6988609	20201924	6.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	121979657	rs939144	G	A	rs939144	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	121979657	rs939144	G	A	rs939144	20201924	7.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	122683440	rs9297647	A	G	rs9297647	21314694	9.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	123772834	rs997795	T	G	rs997795	21314694	9.67E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	124699175	rs17256536	A	G	rs17256536	21314694	9.59E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	125763884	rs16900003	G	A	rs16900003	21314694	8.30E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	126267630	rs7008482	T	G	rs7008482	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	126570279	rs7829236	G	A	rs7829236	20201924	7.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	127335010	rs2253162	A	G	rs2253162	24277619	9.50E-05	NA	0.5	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
8	127478325	rs4870976	G	A	rs4870976	19581569	6.40E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
8	129463535	rs10808570	A	C	rs10808570	20201924	3.49E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	131135269	rs7004884	A	G	rs7004884	21314694	9.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	131442851	rs10956525	T	C	rs10956525	21529783	2.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
8	131744988	rs10505560	T	C	rs10505560	21314694	7.40E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	132567154	rs13275290	G	A	rs13275290	20201924	8.21E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	133159425	rs1595411	G	A	rs1595411	20201924	5.89E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	133161324	rs1991718	C	T	rs1991718	20201924	8.07E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	133831483	rs10956683	G	A	rs10956683	21314694	4.22E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	133967395	rs12677246	C	G	rs12677246	21314694	8.87E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	134519265	rs6989475	A	G	rs6989475	21956439	5.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	137328144	rs16905615	G	A	rs16905615	20201924	4.11E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	140603502	rs2542435	G	A	rs2542435	21314694	2.99E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	140640634	rs2014712	C	T	rs2014712	21314694	8.40E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	140771011	rs11773968	G	T	rs11773968	20201924	8.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	140771011	rs11773968	G	T	rs11773968	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
8	141257264	rs7014855	C	T	rs7014855	21314694	5.77E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	142151713	rs307766	C	T	rs307766	21314694	6.60E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	143324399	rs6583607	T	C	rs6583607	21314694	8.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
8	144183966	rs7846671	A	G	rs7846671	21314694	8.01E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	398673	rs12346176	A	G	rs12346176	21314694	6.60E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	1230619	rs7018922	T	C	rs7018922	19581569	9.63E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
9	1605827	rs702167	G	A	rs702167	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	2237390	rs2376227	C	A	rs2376227	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	2239429	rs4741657	T	C	rs4741657	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	2918656	rs1501576	T	C	rs1501576	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	4505544	rs10814995	A	C	rs10814995	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	4517894	rs17812250	A	G	rs17812250	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	4574022	rs12682807	A	C	rs12682807	21314694	5.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	4758022	rs1756871	G	A	rs1756871	20201924	2.28E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	5987781	rs1993912	A	C	rs1993912	21314694	6.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	7563692	rs2381642	A	G	rs2381642	24277619	6.90E-05	NA	0.54	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
9	7578222	rs4742378	C	T	rs4742378	24277619	4.14E-04	NA	0.45	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
9	7786701	rs10125984	C	T	rs10125984	21314694	6.82E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	8206576	rs1781276	C	T	rs1781276	20201924	5.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	8558331	rs7026937	G	A	rs7026937	24277619	2.96E-04	NA	1.25	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	PTPRD
9	8847233	rs2117099	G	A	rs2117099	20201924	1.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	8847233	rs2117099	G	A	rs2117099	20201924	4.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	8870553	rs12002381	C	T	rs12002381	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	9862171	rs2209192	C	G	rs2209192	21314694	7.44E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	10247217	rs4741020	T	C	rs4741020	20201924	2.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	10260263	rs2475335	C	T	rs2475335	20201924	7.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	12766337	rs10809838	T	G	rs10809838	21314694	8.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	14058548	rs10116586	A	C	rs10116586	21314694	1.11E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	14749434	rs10117516	C	T	rs10117516	24277619	1.37E-04	NA	0.51	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	FREM1
9	14791715	rs1389733	G	T	rs1389733	20201924	1.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	15343709	rs1215130	C	T	rs1215130	20201924	5.08E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	15351450	rs680686	A	G	rs680686	20201924	2.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	15353410	rs7867510	G	A	rs7867510	21314694	3.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	16035672	rs1887671	T	C	rs1887671	21314694	8.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	16321578	rs16934439	T	G	rs16934439	20201924	5.84E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	17474085	rs2441997	G	A	rs2441997	20201924	4.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	18130036	rs10963462	G	T	rs10963462	23089632	0.0000118	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	18130036	rs10963462	G	T	rs10963462	23089632	6.22E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	18134914	rs763976	A	C	rs763976	23089632	0.0000074	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	18134914	rs763976	A	C	rs763976	23089632	0.00001	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	18166899	rs12006002	C	T	rs12006002	23089632	0.000000487	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	18166899	rs12006002	C	T	rs12006002	23089632	7.24E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	18178314	rs34236855	G	A	rs34236855	24962325	9.49E-06	NA	1.37	[1.23-1.51]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
9	18251855	rs10810935	A	G	rs10810935	24962325	2.00E-06	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10810935-A	Research Support, N.I.H., Extramural	A	NA
9	18386757	rs10120545	C	T	rs10120545	21314694	4.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	18601139	rs10963662	A	C	rs10963662	20201924	2.69E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	19014645	rs7030400	C	A	rs7030400	21529783	6.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	20255355	rs1551534	A	G	rs1551534	21314694	6.46E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	20945207	rs6475490	G	C	rs6475490	21314694	9.84E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	21030851	rs11789272	G	A	rs11789272	21314694	5.42E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	23563772	rs10511730	C	T	rs10511730	20201924	1.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	23563772	rs10511730	C	T	rs10511730	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	25658150	rs4144931	C	T	rs4144931	20201924	7.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	26722838	rs10812450	C	T	rs10812450	20201924	7.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	27233968	rs1590255	G	T	rs1590255	20201924	3.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	27233968	rs1590255	G	T	rs1590255	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	27234521	rs7468695	G	A	rs7468695	20201924	4.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	27441537	rs2589053	C	T	rs2589053	21314694	2.83E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	28600142	rs12348435	A	C	rs12348435	24962325	2.00E-06	NA	1.59	[1.39-1.79]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs12348435-C	Research Support, N.I.H., Extramural	A	LINGO2
9	28603940	rs10968666	A	G	rs10968666	24962325	2.29E-06	NA	1.59	[1.39-1.79]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10968666-G	Research Support, N.I.H., Extramural	A	LINGO2
9	30751220	rs10969853	T	C	rs10969853	24962325	5.00E-06	NA	1.61	[1.41-1.81]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10969853-T	Research Support, N.I.H., Extramural	T	NA
9	32884983	rs10122775	C	T	rs10122775	20201924	7.29E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	32899807	rs4879635	G	A	rs4879635	20201924	4.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	33388289	rs17251987	C	T	rs17251987	21314694	9.83E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	36293157	rs7044830	C	T	rs7044830	21314694	3.53E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	36576847	rs10972978	A	G	rs10972978	21314694	3.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	36638245	rs2246564	A	T	rs2246564	21314694	8.22E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	36738641	rs7857754	G	A	rs7857754	20201924	5.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	36740957	rs7873864	G	A	rs7873864	20201924	2.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	36740957	rs7873864	G	A	rs7873864	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	36741027	rs10116484	C	T	rs10116484	20201924	2.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	36741027	rs10116484	C	T	rs10116484	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	36885746	rs3824339	G	A	rs3824339	21314694	3.27E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	71211602	rs7032966	C	T	rs7032966	21314694	4.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	73224560	rs10114679	C	T	rs10114679	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	74325433	rs1010434	C	T	rs1010434	21314694	7.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	76187539	rs157113	T	C	rs157113	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	77690749	rs2376397	C	T	rs2376397	21529783	1.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	78069679	rs516609	C	T	rs516609	23089632	1.35E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	82729842	rs971258	C	T	rs971258	21529783	6.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
9	82730333	rs10512096	T	C	rs10512096	21529783	5.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	82743820	rs1328433	A	G	rs1328433	21529783	5.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	83898995	rs7042916	G	A	rs7042916	20201924	1.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	84520436	rs7018590	A	G	rs7018590	21314694	4.02E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	87632318	rs4877900	C	T	rs4877900	21314694	9.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	87647434	rs1586681	G	T	rs1586681	21314694	3.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	87795226	rs329200	A	G	rs329200	20201924	9.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	88728064	rs7867760	G	C	rs7867760	21314694	8.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	89375314	rs994029	C	T	rs994029	23691058	0.000000198	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	89586340	rs12554360	C	T	rs12554360	21314694	8.13E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	90896077	rs10868746	G	A	rs10868746	20201924	1.42E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91732709	rs13295927	T	C	rs13295927	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91732709	rs13295927	T	C	rs13295927	20201924	6.30E-06	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91732709	rs13295927	T	C	rs13295927	pha002893	6.31E-06	phs000125	1.92	[1.45-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	SHC3	intron	NM_016848
9	91848678	rs12341391	A	G	rs12341391	20201924	2.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91848678	rs12341391	A	G	rs12341391	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91878702	rs10441779	C	T	rs10441779	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91878702	rs10441779	C	T	rs10441779	20201924	3.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91906139	rs13294002	T	G	rs13294002	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91906139	rs13294002	T	G	rs13294002	20201924	7.20E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	91906139	rs13294002	T	G	rs13294002	pha002893	7.20E-05	phs000125	1.82	[1.35-2.44]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
9	92249584	rs10908907	G	A	rs10908907	21529783	6.00E-06	NA	0.1	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs10908907-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
9	94222921	rs10820857	G	A	rs10820857	20201924	1.29E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	94225537	rs1591068	G	A	rs1591068	20201924	8.21E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	94225537	rs1591068	G	A	rs1591068	pha002891	8.21E-05	phs000125	1.96	[1.41-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
9	94235377	rs1855065	T	G	rs1855065	20201924	4.28E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	94235377	rs1855065	T	G	rs1855065	pha002891	4.28E-05	phs000125	2.33	[1.56-3.45]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
9	94488415	rs4073735	C	T	rs4073735	21314694	7.65E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	94985637	rs556155	T	C	rs556155	21314694	9.69E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	95101729	rs10820967	G	C	rs10820967	21314694	9.23E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	95220601	rs10820978	G	T	rs10820978	21314694	4.14E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	95487497	rs10821008	G	A	rs10821008	21314694	6.79E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	95881054	rs13285107	C	T	rs13285107	20201924	5.69E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	96144349	rs2086106	T	C	rs2086106	21314694	8.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	96415899	rs11793637	A	G	rs11793637	21314694	5.55E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	98360116	rs1932075	C	T	rs1932075	21314694	8.63E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	99946041	rs10980992	C	T	rs10980992	24277619	3.31E-04	NA	0.73	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	ANKRD18CP
9	106304253	rs9299372	A	C	rs9299372	21529783	9.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	106345310	rs1396554	A	G	rs1396554	21529783	9.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
9	109631825	rs17787921	C	T	rs17787921	20201924	4.49E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	110006085	rs1323806	C	T	rs1323806	20201924	8.67E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	110712165	rs10979126	G	A	rs10979126	20201924	1.13E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	110923018	rs4542003	T	C	rs4542003	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	110940319	rs1412428	G	A	rs1412428	20201924	3.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	110940360	rs1412427	C	T	rs1412427	20201924	5.73E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	112933781	rs10125067	A	G	rs10125067	20201924	8.99E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	113581359	rs509276	G	A	rs509276	20201924	1.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	113581359	rs509276	G	A	rs509276	20201924	2.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	113581359	rs509276	G	A	rs509276	pha002892	2.53E-05	phs000125	1.56	[1.27-1.92]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
9	115894240	rs7867889	G	A	rs7867889	21529783	3.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
9	115904129	rs4979215	C	T	rs4979215	21529783	5.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
9	116741439	rs10513224	A	C	rs10513224	21314694	8.26E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	116874355	rs1570589	A	G	rs1570589	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	117314774	rs10982289	G	A	rs10982289	20201924	1.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	117314774	rs10982289	G	A	rs10982289	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	117430611	rs1359992	A	T	rs1359992	21314694	2.44E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	118223430	rs1632812	G	A	rs1632812	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	118254988	rs10982769	T	C	rs10982769	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	119612028	rs1326814	C	T	rs1326814	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	119616042	rs1536428	A	G	rs1536428	20201924	1.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	119709428	rs13288277	A	G	rs13288277	20201924	7.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	124331759	rs1757321	C	T	rs1757321	21314694	1.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	125001985	rs10733657	C	T	rs10733657	20201924	1.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	125003528	rs7042018	A	G	rs7042018	20201924	4.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	125377505	rs1329957	A	G	rs1329957	20201924	2.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	125384788	rs10739616	A	G	rs10739616	20201924	2.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	130776407	rs4837223	C	T	rs4837223	21314694	7.81E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	132163254	rs4837362	A	C	rs4837362	24277619	2.50E-04	NA	0.59	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
9	132352219	rs10988439	G	T	rs10988439	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	132617888	rs7858348	G	A	rs7858348	21314694	9.83E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	135114365	rs2274853	G	A	rs2274853	20201924	6.63E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
9	136139265	rs657152	C	A	rs657152	21529783	4.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
9	137736544	rs4504708	G	T	rs4504708	21314694	2.54E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	138195203	rs4841962	A	C	rs4841962	24277619	8.67E-04	NA	0.39	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
9	139559127	rs7041558	A	G	rs7041558	24277619	9.81E-04	NA	0.46	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	EGFL7
9	139823622	rs2386140	A	G	rs2386140	21314694	7.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	139830940	rs6560652	T	C	rs6560652	21314694	1.08E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	139857912	rs11145948	G	A	rs11145948	21314694	2.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
9	139978619	rs17065341	A	G	rs17065341	21314694	5.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	1854773	rs12570407	C	T	rs12570407	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	2154862	rs12776254	A	G	rs12776254	20202923	1.82E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	2154862	rs12776254	A	G	rs12776254	21703634	6.81E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
10	2703572	rs17158770	C	T	rs17158770	24277619	9.89E-04	NA	0.57	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
10	2715418	rs11597478	G	A	rs11597478	24277619	1.25E-04	NA	1.58	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
10	2722162	rs10903843	A	G	rs10903843	24277619	6.10E-04	NA	0.86	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
10	3150371	rs4881084	G	A	rs4881084	23089632	1.43E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	3176389	rs2306311	C	T	rs2306311	21314694	4.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	3186943	rs7097793	G	C	rs7097793	21314694	1.10E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	3333530	rs17135017	G	A	rs17135017	20201924	4.30E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	3333530	rs17135017	G	A	rs17135017	pha002892	4.32E-06	phs000125	1.67	[1.33-2.08]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
10	3335447	rs11251836	G	T	rs11251836	20201924	2.90E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	3335447	rs11251836	G	T	rs11251836	pha002892	2.88E-05	phs000125	1.82	[1.39-2.44]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
10	4829103	rs2397990	C	T	rs2397990	20201924	2.29E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	5147909	rs2275928	G	A	rs2275928	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	5331159	rs2398236	A	G	rs2398236	23691058	0.00000907	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
10	5332349	rs9423593	C	T	rs9423593	23691058	0.00000832	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
10	5333008	rs7076488	G	A	rs7076488	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	5333008	rs7076488	G	A	rs7076488	23691058	0.00000213	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
10	5355712	rs9423407	C	T	rs9423407	20201924	9.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	5689058	rs11256831	G	T	rs11256831	21703634	7.15E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
10	6292607	rs2185691	T	C	rs2185691	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	7611498	rs12247601	T	C	rs12247601	21529783	8.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
10	9020234	rs827628	T	C	rs827628	20201924	3.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	10277345	rs17527069	T	C	rs17527069	20201924	5.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	11795575	rs4750099	G	T	rs4750099	21314694	4.87E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	16873547	rs3740169	G	A	rs3740169	21314694	5.13E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	17351794	rs400333	A	G	rs400333	21314694	4.82E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	17596121	rs6602203	C	T	rs6602203	21314694	8.74E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	17962530	rs544313	G	A	rs544313	20201924	1.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	18372986	rs12255303	A	G	rs12255303	24277619	1.21E-04	NA	0.66	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
10	19795045	rs6481955	A	G	rs6481955	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	19796430	rs3852465	T	C	rs3852465	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	19807875	rs10494868	C	A	rs10494868	20201924	6.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	22341895	rs11812890	T	C	rs11812890	21314694	1.89E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	24014122	rs4748908	A	G	rs4748908	21314694	6.63E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	24707669	rs2366915	C	T	rs2366915	24277619	9.66E-04	NA	0.42	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	KIAA1217
10	24803057	rs4748949	G	A	rs4748949	21529783	7.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A,G
10	25174726	rs7078551	C	T	rs7078551	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	25776176	rs3005191	A	G	rs3005191	20201924	4.54E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	25996101	rs10764581	T	C	rs10764581	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	26955598	rs1009273	A	G	rs1009273	21314694	2.96E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	28373644	rs4749301	T	C	rs4749301	20201924	5.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	29871949	rs7079620	G	A	rs7079620	21314694	9.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	31580605	rs16932309	C	A	rs16932309	21314694	6.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	32357556	rs4747764	G	A	rs4747764	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	32393213	rs211409	T	C	rs211409	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	32398895	rs211424	T	C	rs211424	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	32400396	rs73477	G	A	rs73477	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	38416473	rs16937688	C	T	rs16937688	21314694	7.20E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	42981695	rs1889310	A	T	rs1889310	20201924	8.46E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	48353676	rs7090464	T	C	rs7090464	21314694	7.29E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	52039157	rs2813323	G	A	rs2813323	20201924	7.79E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	53020936	rs10490975	G	T	rs10490975	20201924	7.21E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	53608977	rs1937701	C	T	rs1937701	20201924	1.51E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	53613913	rs7080306	C	T	rs7080306	20201924	9.57E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	53613913	rs7080306	C	T	rs7080306	pha002891	9.57E-05	phs000125	1.97	[1.40-2.77]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	PRKG1	intron	NM_001098512
10	53806602	rs17641137	C	T	rs17641137	20201924	5.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	54361898	rs10824650	A	G	rs10824650	20201924	8.77E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	54399802	rs959781	C	T	rs959781	20201924	1.67E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	55343454	rs3120130	A	G	rs3120130	20201924	5.09E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	55344712	rs351847	T	C	rs351847	20201924	4.54E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	55357136	rs1932011	A	C	rs1932011	20201924	8.49E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	55357136	rs1932011	A	C	rs1932011	pha002891	8.49E-05	phs000125	2.08	[1.45-3.03]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
10	55365419	rs7904493	C	A	rs7904493	20201924	3.89E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	55367569	rs1489843	G	A	rs1489843	20201924	4.58E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	55381191	rs9416285	C	T	rs9416285	20201924	4.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	55413116	rs9416295	T	C	rs9416295	20201924	9.93E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	55413116	rs9416295	T	C	rs9416295	pha002891	9.93E-05	phs000125	2.5	[1.59-4.00]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
10	55421304	rs825820	T	C	rs825820	20201924	1.11E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	56900638	rs10825471	A	G	rs10825471	20201924	8.36E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	56972812	rs2247977	G	A	rs2247977	21529783	6.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
10	59559120	rs17625002	T	G	rs17625002	24962325	3.93E-06	NA	1.41	[1.27-1.55]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
10	59559319	rs56299213	C	T	rs56299213	24962325	3.93E-06	NA	1.41	[1.27-1.55]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
10	59560685	rs11594537	T	C	rs11594537	24962325	5.36E-06	NA	1.41	[1.27-1.55]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
10	59572370	rs7909889	C	T	rs7909889	24962325	3.29E-06	NA	1.41	[1.27-1.55]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
10	59572708	rs17625382	G	A	rs17625382	24962325	3.00E-06	NA	1.41	[1.27-1.55]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs17625382-G	Research Support, N.I.H., Extramural	G	NA
10	59969111	rs12261547	G	C	rs12261547	21314694	2.05E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	62070753	rs10821716	C	T	rs10821716	21314694	6.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	64307317	rs2138564	C	T	rs2138564	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	64668048	rs10509177	C	T	rs10509177	21529783	9.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
10	65587937	rs4427464	T	G	rs4427464	24277619	6.28E-04	NA	0.5	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
10	65650779	rs884242	C	T	rs884242	24277619	3.15E-04	NA	0.5	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
10	66762723	rs7904001	G	A	rs7904001	20201924	6.55E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	68482454	rs10997361	C	T	rs10997361	20201924	2.94E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	68861272	rs2394340	T	C	rs2394340	21314694	8.03E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	69222470	rs10997651	A	C	rs10997651	20201924	2.08E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	72462283	rs12775317	G	A	rs12775317	21956439	6.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	72996234	rs12766963	C	T	rs12766963	21314694	9.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	73326340	rs10999882	C	T	rs10999882	20201924	1.23E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	73454637	rs10823825	T	C	rs10823825	20201924	5.52E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	74764074	rs12573768	G	A	rs12573768	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	74767695	rs16930262	C	T	rs16930262	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	74776781	rs7085141	A	G	rs7085141	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	76505571	rs10824233	G	A	rs10824233	20201924	4.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	78028463	rs10762705	G	A	rs10762705	23089632	0.000013483	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	78918297	rs10824494	C	A,G	rs10824494	24277619	8.58E-04	NA	4.68	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	KCNMA1
10	79043364	rs717207	G	T	rs717207	21314694	2.17E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	79146116	rs2077641	G	C	rs2077641	21314694	7.92E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	79173540	rs12219105	T	C	rs12219105	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	79173540	rs12219105	T	C	rs12219105	20201924	9.70E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	79173540	rs12219105	T	C	rs12219105	pha002893	9.68E-05	phs000125	1.79	[1.33-2.38]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	KCNMA1	intron	NM_002247
10	79549242	rs2812431	C	T	rs2812431	21314694	1.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	80131442	rs10490996	G	A	rs10490996	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	80145435	rs719871	C	T	rs719871	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	81915136	rs2789686	T	C	rs2789686	21529783	1.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
10	84223466	rs1937970	A	G	rs1937970	24277619	7.37E-04	NA	0.42	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NRG3
10	85613835	rs11200700	A	G	rs11200700	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85613835	rs11200700	A	G	rs11200700	pha002891	1.00E-04	phs000125	2	[1.41-2.86]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
10	85789310	rs6585783	T	C	rs6585783	20201924	3.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85789310	rs6585783	T	C	rs6585783	20201924	4.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85789310	rs6585783	T	C	rs6585783	20202923	8.02E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	85795618	rs7068193	G	A	rs7068193	20201924	1.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85795618	rs7068193	G	A	rs7068193	20201924	6.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85795618	rs7068193	G	A	rs7068193	pha002893	6.40E-05	phs000125	1.52	[1.23-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
10	85798580	rs4615965	C	T	rs4615965	20201924	1.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85798580	rs4615965	C	T	rs4615965	20201924	8.60E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85798580	rs4615965	C	T	rs4615965	pha002893	8.65E-05	phs000125	1.49	[1.22-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
10	85802965	rs7076979	G	T	rs7076979	20201924	1.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85802965	rs7076979	G	T	rs7076979	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85803792	rs7906877	C	T	rs7906877	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85803792	rs7906877	C	T	rs7906877	20201924	8.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	85803792	rs7906877	C	T	rs7906877	pha002893	8.92E-05	phs000125	1.49	[1.22-1.82]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
10	86355239	rs11597975	A	G	rs11597975	24277619	7.72E-04	NA	0.77	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
10	89411554	rs791887	T	C	rs791887	21314694	5.04E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	90693569	rs1372325	T	C	rs1372325	21529783	7.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
10	92576448	rs11186320	T	C	rs11186320	21314694	7.92E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	95064137	rs10882215	G	T	rs10882215	20201924	8.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	97026458	rs7912686	T	C	rs7912686	21314694	3.99E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	97759203	rs2039617	G	A	rs2039617	21956439	1.40E-05	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	98766221	rs11188984	C	T	rs11188984	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	100089210	rs7075856	C	A	rs7075856	21314694	7.98E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	101452369	rs11813439	G	A	rs11813439	20201924	3.15E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	101452369	rs11813439	G	A	rs11813439	pha002891	3.15E-05	phs000125	2.63	[1.67-4.17]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	ENTPD7	intron	NM_020354
10	101494991	rs17112202	T	C	rs17112202	20201924	8.74E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	101494991	rs17112202	T	C	rs17112202	pha002891	8.74E-05	phs000125	3.23	[1.79-5.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	CUTC	intron	NM_015960
10	102672718	rs3802724	T	C	rs3802724	20201924	3.37E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	102673292	rs4917916	G	A	rs4917916	20201924	4.69E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	102692604	rs12241232	T	C	rs12241232	20201924	4.89E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	102692970	rs7911957	A	G	rs7911957	20201924	3.37E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	102775205	rs701837	T	C	rs701837	20201924	1.20E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	102775205	rs701837	T	C	rs701837	pha002892	1.19E-06	phs000125	1.02	[0.85-1.23]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	PDZD7	intron	NM_001195263
10	105603163	rs12573437	C	A	rs12573437	20201924	6.76E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	108861967	rs11193198	G	A	rs11193198	21314694	7.54E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	111197730	rs7092048	T	C	rs7092048	23089632	2.33E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	112750629	rs11195397	C	T	rs11195397	20201924	3.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	112858575	rs11593780	C	T	rs11593780	21314694	5.39E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	112862029	rs945333	T	C	rs945333	23089632	2.06E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	115330130	rs4918853	T	C	rs4918853	21314694	6.92E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	115421996	rs3121491	G	A	rs3121491	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	115464171	rs3124743	A	G	rs3124743	20201924	2.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	115464171	rs3124743	A	G	rs3124743	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	115480582	rs11196449	T	C	rs11196449	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	115480582	rs11196449	T	C	rs11196449	20201924	9.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	115746419	rs17653713	C	A,G,T	rs17653713	24277619	3.54E-04	NA	0.67	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
10	118560477	rs7097645	A	G	rs7097645	21314694	8.47E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	118962873	rs963975	G	C	rs963975	21314694	1.78E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	119043554	rs363294	C	T	rs363294	21703634	5.56E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
10	119051788	rs2532812	G	A	rs2532812	21703634	3.63E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
10	120697691	rs7905194	C	T	rs7905194	21314694	6.05E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	120952674	rs10886416	C	A	rs10886416	24277619	4.59E-04	NA	1.21	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
10	121212405	rs2297641	C	T	rs2297641	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	121216923	rs1999627	G	A	rs1999627	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	121217061	rs1999628	T	A	rs1999628	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	121217683	rs11198934	C	T	rs11198934	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	121218572	rs10886486	A	C	rs10886486	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	121383036	rs196313	G	A	rs196313	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	121411861	rs196335	C	T	rs196335	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	124097427	rs11200559	G	T	rs11200559	pha002893	8.33E-05	phs000125	1.65	[1.29-2.12]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	BTBD16	intron	NM_144587
10	124690291	rs17653439	G	A	rs17653439	20201924	7.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	124690291	rs17653439	G	A	rs17653439	20201924	8.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	124993940	rs12773354	C	T	rs12773354	21314694	8.95E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	126343931	rs3781458	C	T	rs3781458	23691058	0.00000427	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
10	126355129	rs3781452	C	T	rs3781452	23691058	0.00000686	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
10	126675365	rs11596226	T	G	rs11596226	21314694	8.19E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	126696872	rs4962416	T	C	rs4962416	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	126702049	rs12781214	C	T	rs12781214	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	126706676	rs11595908	C	T	rs11595908	21314694	8.59E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	129227488	rs11018077	G	A	rs11018077	20201924	7.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	131510293	rs4751115	T	C	rs4751115	21314694	4.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	131519512	rs10829622	T	C	rs10829622	21314694	4.58E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	131772971	rs7099076	T	C	rs7099076	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	131772971	rs7099076	T	C	rs7099076	20201924	4.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	131815674	rs942950	T	C	rs942950	21314694	5.96E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	132431119	rs16911018	G	A	rs16911018	20201924	1.93E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
10	132881848	rs3902786	A	T	rs3902786	21314694	1.31E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
10	135282201	rs2814209	T	C	rs2814209	21314694	4.79E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	771034	rs7930569	A	G	rs7930569	20201924	6.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	840034	rs11246327	C	A	rs11246327	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	1068233	rs12146505	T	G	rs12146505	20201924	3.68E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	1068233	rs12146505	T	G	rs12146505	pha002891	3.68E-05	phs000125	2.38	[1.56-3.57]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
11	1857270	rs907609	C	T	rs907609	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	1888955	rs11041553	G	A	rs11041553	20201924	2.86E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	1888955	rs11041553	G	A	rs11041553	pha002891	2.86E-05	phs000125	5.56	[2.50-12.50]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	LSP1	intron	NM_002339
11	2681118	rs12574151	T	G	rs12574151	20201924	4.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	2681118	rs12574151	T	G	rs12574151	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	2956166	rs2583442	T	C	rs2583442	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	2956166	rs2583442	T	C	rs2583442	20201924	8.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	2958818	rs2583435	T	C	rs2583435	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	2958818	rs2583435	T	C	rs2583435	20201924	7.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	2999507	rs3814964	G	T	rs3814964	20201924	7.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	2999507	rs3814964	G	T	rs3814964	20201924	7.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	2999507	rs3814964	G	T	rs3814964	pha002892	7.45E-05	phs000125	1.45	[1.20-1.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NAP1L4	intron	NM_005969
11	3009640	rs4758621	A	G	rs4758621	20201924	3.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3020740	rs12805661	C	T	rs12805661	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3020740	rs12805661	C	T	rs12805661	20201924	6.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3028140	rs729662	G	A	rs729662	20201924	3.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3028140	rs729662	G	A	rs729662	20201924	8.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3028140	rs729662	G	A	rs729662	pha002892	8.52E-05	phs000125	1.45	[1.20-1.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	CARS	cds-synon	NM_139273
11	3029089	rs7481584	G	A	rs7481584	20201924	4.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3029089	rs7481584	G	A	rs7481584	20201924	9.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3029089	rs7481584	G	A	rs7481584	pha002892	9.54E-05	phs000125	1.43	[1.19-1.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	CARS	intron	NM_139273
11	3046201	rs428726	G	A	rs428726	20201924	4.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3046201	rs428726	G	A	rs428726	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3046298	rs377765	C	T	rs377765	20201924	4.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3046298	rs377765	C	T	rs377765	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3050210	rs434114	A	G	rs434114	20201924	7.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3050210	rs434114	A	G	rs434114	20201924	8.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3060725	rs451041	A	G	rs451041	20201924	1.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3060725	rs451041	A	G	rs451041	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3061992	rs369461	T	C	rs369461	20201924	4.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3061992	rs369461	T	C	rs369461	20201924	5.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3076285	rs406598	G	A	rs406598	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3076285	rs406598	G	A	rs406598	20201924	5.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3143030	rs6578322	T	C	rs6578322	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3150086	rs4758533	A	G	rs4758533	20201924	4.80E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3150086	rs4758533	A	G	rs4758533	pha002892	4.82E-05	phs000125	1.52	[1.25-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	OSBPL5	intron	NM_145638
11	3165412	rs4468331	G	A	rs4468331	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3266133	rs10766825	T	C	rs10766825	21314694	9.90E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	3691417	rs2672213	C	T	rs2672213	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	3856553	rs1451722	C	T	rs1451722	23089632	4.35E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	3856668	rs1451724	G	A	rs1451724	23089632	6.68E-07	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	5029457	rs11035102	A	G	rs11035102	23089632	4.37E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	5922707	rs7106300	C	T	rs7106300	20201924	3.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	5923297	rs4601752	A	G	rs4601752	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	5924061	rs7129741	A	G	rs7129741	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	6397336	rs2101469	T	C	rs2101469	20201924	5.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	6720186	rs10839595	G	A	rs10839595	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	7384411	rs977749	T	C	rs977749	21529783	7.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
11	7613349	rs4472926	A	G	rs4472926	21314694	6.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	8704091	rs10840110	C	T	rs10840110	21314694	9.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	11290071	rs4910291	G	A	rs4910291	20201924	8.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	11779374	rs874651	C	T	rs874651	21529783	7.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
11	12367806	rs10831798	T	C	rs10831798	20201924	2.78E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	12367806	rs10831798	T	C	rs10831798	pha002891	2.78E-05	phs000125	2.04	[1.45-2.86]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	MICALCL	intron	NM_032867
11	12368645	rs4757381	G	A	rs4757381	20201924	8.95E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	12368645	rs4757381	G	A	rs4757381	pha002891	8.95E-05	phs000125	2.13	[1.45-3.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	MICALCL	intron	NM_032867
11	12911236	rs10831916	C	T	rs10831916	20201924	4.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	13237709	rs11022710	T	C	rs11022710	20201924	7.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	13239500	rs7112005	T	C	rs7112005	20201924	3.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	13239559	rs7108752	A	G	rs7108752	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	13250399	rs10832000	A	G	rs10832000	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	13997808	rs12575169	A	C	rs12575169	21314694	9.34E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	14273677	rs731274	G	A	rs731274	20201924	1.58E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	14276999	rs2303975	G	A	rs2303975	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	14318830	rs11023182	G	T	rs11023182	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	14342761	rs11023186	G	A	rs11023186	20201924	9.66E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	14342761	rs11023186	G	A	rs11023186	pha002891	9.66E-05	phs000125	2.22	[1.49-3.33]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	RRAS2	intron	NM_012250
11	14373662	rs2349300	T	C	rs2349300	20201924	2.75E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	14918216	rs1562902	C	T	rs1562902	24277619	7.36E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
11	14918308	rs16930625	A	G	rs16930625	24277619	4.54E-04	NA	0.61	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
11	15456468	rs11023571	G	A	rs11023571	24277619	8.79E-04	NA	0.46	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
11	16394068	rs1370465	G	A	rs1370465	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	16408248	rs11603071	T	C	rs11603071	20201924	3.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	16452132	rs1503452	C	T	rs1503452	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	16452132	rs1503452	C	T	rs1503452	23691058	0.00000321	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
11	17726374	rs4757574	A	G	rs4757574	21529783	1.00E-04	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	19488083	rs1386449	A	G	rs1386449	20202923	5.68E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	19488083	rs1386449	A	G	rs1386449	21956439	4.20E-05	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	20199278	rs11025421	C	A	rs11025421	24277619	7.71E-04	NA	0.77	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
11	20617011	rs12791734	T	A	rs12791734	21314694	9.92E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	20853246	rs11825833	T	C	rs11825833	21314694	8.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	21015060	rs10500885	T	C	rs10500885	20201924	7.76E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	21016295	rs1400369	A	C	rs1400369	20201924	6.47E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	21950485	rs1487814	T	C	rs1487814	19581569	8.04E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
11	25846889	rs12418699	T	C	rs12418699	24277619	8.25E-04	NA	0.41	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
11	26826710	rs10767583	C	T	rs10767583	24277619	7.40E-05	NA	0.45	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
11	30165896	rs930321	T	C	rs930321	20201924	4.26E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	30651019	rs449438	A	C	rs449438	21314694	5.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	32838288	rs197710	A	G	rs197710	21314694	4.07E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	32895664	rs10767971	T	C	rs10767971	20201924	4.83E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	32905094	rs4756329	T	A	rs4756329	21314694	3.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	33415151	rs12291056	G	A	rs12291056	20201924	2.13E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	33415151	rs386752273	GGG	GTA	rs12291056	20201924	2.13E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	33709273	rs831620	A	G	rs831620	20201924	3.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	33709273	rs831620	A	G	rs831620	20201924	3.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	33709273	rs831620	A	G	rs831620	pha002893	3.87E-05	phs000125	1.52	[1.25-1.86]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
11	33714641	rs2746600	A	G	rs2746600	pha002893	8.29E-05	phs000125	1.52	[1.23-1.86]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
11	34187847	rs745809	G	A	rs745809	21314694	3.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	34449260	rs16925514	G	T	rs16925514	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	34449260	rs16925514	G	T	rs16925514	21703634	6.68E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	34450461	rs12295136	T	C	rs12295136	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	34450461	rs12295136	T	C	rs12295136	21703634	9.45E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	34456208	rs1107573	C	T	rs1107573	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	34456208	rs1107573	C	T	rs1107573	21703634	6.60E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	34461665	rs12272630	G	C	rs12272630	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	34461665	rs12272630	G	C	rs12272630	21703634	6.95E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	34468123	rs11032702	C	T	rs11032702	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	34468123	rs11032702	C	T	rs11032702	21703634	6.95E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	34472774	rs12269988	A	G	rs12269988	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	34472774	rs12269988	A	G	rs12269988	21703634	5.25E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	34479711	rs12273124	A	G	rs12273124	21703634	6.95E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	34659807	rs7936502	G	T	rs7936502	19581569	1.61E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
11	36095347	rs11033401	G	A	rs11033401	21314694	4.21E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	36356242	rs12418187	C	T	rs12418187	21314694	1.29E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	36447369	rs2292648	A	G	rs2292648	20201924	9.30E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	36447369	rs2292648	A	G	rs2292648	pha002892	9.25E-05	phs000125	1.61	[1.27-2.04]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	PRR5L	intron	NM_024841
11	36777339	rs4756348	T	G	rs4756348	21314694	4.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	39902443	rs10768556	C	A	rs10768556	20201924	4.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	39933968	rs10837301	A	C	rs10837301	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	39989962	rs7111117	T	C	rs7111117	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	40041290	rs6485172	A	G	rs6485172	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	40073820	rs10768576	G	A	rs10768576	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	40092793	rs16934315	T	C	rs16934315	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	40226381	rs4369393	G	T	rs4369393	21314694	9.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	40302006	rs10501226	T	C	rs10501226	21314694	6.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	42247461	rs12364934	T	G	rs12364934	20201924	5.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	42305063	rs12366192	T	C	rs12366192	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	43449285	rs3816766	T	C	rs3816766	21314694	2.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	45663568	rs1348965	T	C	rs1348965	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	45968661	rs11038720	A	T	rs11038720	21314694	3.69E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	48102806	rs6485806	C	T	rs6485806	24277619	9.24E-04	NA	0.57	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	PTPRJ
11	58438655	rs12798524	A	G	rs12798524	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	58440720	rs1014968	C	T	rs1014968	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	58693686	rs550864	G	T	rs550864	21314694	9.79E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	61379646	rs2429862	C	T	rs2429862	20201924	2.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	61692341	rs17156580	C	T	rs17156580	21314694	8.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	64331462	rs17300741	A	G	rs17300741	20201924	4.69E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	65802478	rs12576969	A	G	rs12576969	24277619	9.71E-04	NA	0.5	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
11	66319262	rs10791881	G	A	rs10791881	20201924	1.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	66319262	rs10791881	G	A	rs10791881	20201924	6.20E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	66319262	rs10791881	G	A	rs10791881	pha002892	6.16E-05	phs000125	1.44	[1.21-1.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	ACTN3	intron	NM_001104
11	66319262	rs10791881	G	A	rs10791881	pha002893	1.93E-05	phs000125	1.57	[1.28-1.93]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	ACTN3	intron	NM_001104
11	69952562	rs755016	G	A	rs755016	21529783	2.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
11	70526345	rs7940843	T	C	rs7940843	21529783	4.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
11	70789000	rs11238042	G	A	rs11238042	21529783	5.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
11	70829858	rs3924047	T	C	rs3924047	23691058	0.00000877	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
11	72935825	rs7111814	C	T	rs7111814	21314694	7.27E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	72995912	rs1790063	G	A	rs1790063	21314694	5.24E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	73365615	rs642490	A	G	rs642490	21314694	6.28E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	74996081	rs512797	G	A	rs512797	21314694	9.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	75956348	rs2226615	G	A	rs2226615	21314694	3.36E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	76412663	rs7127747	G	A	rs7127747	24277619	5.23E-04	NA	0.47	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	GUCY2E
11	76758592	rs4944137	G	C	rs4944137	21314694	7.99E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	79817252	rs998023	A	G	rs998023	20201924	8.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	80016503	rs11826437	T	G	rs11826437	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	81752743	rs656948	C	T	rs656948	21529783	3.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	83766621	rs4943885	A	G	rs4943885	21314694	9.69E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	84409477	rs1940094	C	T	rs1940094	20201924	7.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	86795933	rs17149719	T	C	rs17149719	21529783	1.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
11	86795933	rs17149719	T	C	rs17149719	21703634	3.80E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	86889284	rs1948206	C	T	rs1948206	21703634	6.69E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	86889448	rs4944672	C	T	rs4944672	21703634	6.42E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	86895621	rs17149800	T	C	rs17149800	21703634	9.25E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	87879627	rs302665	A	G	rs302665	21703634	5.93E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	87936024	rs633687	G	A	rs633687	21703634	6.44E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	88117962	rs7930237	A	G	rs7930237	21956439	9.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	88412451	rs6483362	A	G	rs6483362	21956439	1.60E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	88447646	rs1391875	G	C	rs1391875	21314694	6.03E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	93277266	rs7126188	C	T	rs7126188	20201924	4.59E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	95756412	rs607395	G	A	rs607395	21314694	3.18E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	95957204	rs12417347	A	G	rs12417347	20201924	7.45E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	101536336	rs1938831	T	C	rs1938831	23089632	4.63E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	102423666	rs7110424	G	T	rs7110424	20201924	8.62E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	103056680	rs17374436	T	C	rs17374436	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	105844065	rs609665	C	T	rs609665	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	106675310	rs10890597	A	G	rs10890597	21314694	9.31E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	107549519	rs10890750	G	A	rs10890750	21314694	7.68E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	108384661	rs12146448	C	A	rs12146448	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	110748070	rs10488719	G	A	rs10488719	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	111250650	rs4356268	A	G	rs4356268	20201924	5.84E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	113199146	rs10502172	C	T	rs10502172	20201924	2.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	113199146	rs10502172	C	T	rs10502172	20201924	7.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	113211370	rs10891537	T	G	rs10891537	20201924	3.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	113211370	rs10891537	T	G	rs10891537	20201924	7.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	114642623	rs7113782	A	C	rs7113782	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116118912	rs1009746	T	G	rs1009746	20201924	1.80E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116118912	rs1009746	T	G	rs1009746	20201924	4.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116118912	rs1009746	T	G	rs1009746	pha002892	4.03E-05	phs000125	1.04	[0.87-1.25]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
11	116118912	rs1009746	T	G	rs1009746	pha002893	1.83E-05	phs000125	1.03	[0.83-1.27]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
11	116126460	rs10891936	G	A	rs10891936	20201924	3.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116126460	rs10891936	G	A	rs10891936	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116126804	rs10891937	G	A	rs10891937	20201924	1.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116126804	rs10891937	G	A	rs10891937	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116129017	rs17473320	C	T	rs17473320	20201924	3.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116129017	rs17473320	C	T	rs17473320	20201924	8.80E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116129017	rs17473320	C	T	rs17473320	pha002893	8.79E-05	phs000125	1.47	[1.21-1.79]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
11	116131952	rs7128824	A	C	rs7128824	20201924	1.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116131952	rs7128824	A	C	rs7128824	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116139119	rs4938246	G	A	rs4938246	20201924	1.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	116139119	rs4938246	G	A	rs4938246	20201924	7.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	117461602	rs553637	C	T	rs553637	23089632	2.00E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	117908328	rs3016863	A	G	rs3016863	21314694	5.11E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	118765283	rs665648	G	A	rs665648	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	118943599	rs4531480	T	C	rs4531480	21314694	3.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	120167057	rs4142654	A	G	rs4142654	21314694	5.76E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	121223996	rs4936618	A	C	rs4936618	20201924	8.79E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	121568116	rs17337279	C	T	rs17337279	21314694	5.61E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	121779664	rs747915	T	C	rs747915	24277619	3.21E-04	NA	0.49	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
11	121815423	rs1448130	G	A	rs1448130	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	122452193	rs7925049	A	G	rs7925049	21529783	3.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	124995104	rs10893332	C	T	rs10893332	20201924	6.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	124997521	rs597900	C	T	rs597900	20201924	2.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	125001843	rs585977	G	A	rs585977	20201924	6.20E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	125001843	rs585977	G	A	rs585977	pha002892	6.15E-05	phs000125	1.56	[1.25-1.94]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
11	125006353	rs601813	A	G	rs601813	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	125170639	rs1426153	A	G	rs1426153	21703634	1.01E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	125171374	rs11220015	G	A	rs11220015	21703634	3.66E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	125171431	rs11602925	A	G	rs11602925	21703634	2.31E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	125172593	rs750338	A	G	rs750338	20202923	2.39E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	125172593	rs750338	A	G	rs750338	21703634	1.00E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs750338-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	125172593	rs750338	A	G	rs750338	21956439	7.50E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	125176437	rs10893365	T	C	rs10893365	21703634	9.55E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	125176437	rs10893365	T	C	rs10893365	21956439	3.60E-05	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	125178403	rs10893366	C	T	rs10893366	21703634	1.61E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	125178403	rs10893366	C	T	rs10893366	21956439	8.00E-06	EA + AA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	125179853	rs12284594	A	G	rs12284594	20202923	8.12E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	125179853	rs12284594	A	G	rs12284594	21703634	6.53E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	125179853	rs12284594	A	G	rs12284594	21956439	9.70E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	127900579	rs1785039	A	G	rs1785039	21529783	6.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	130934617	rs4937598	G	A	rs4937598	20201924	2.12E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
11	132492426	rs4936173	C	T	rs4936173	21314694	3.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	132584119	rs1793257	C	T	rs1793257	23942779	7.00E-06	NA	0.83	[NA] unit increase	7,188 European ancestry individuals	European(7188)	ALL(7188)	EUR(7188)	ALL(7188)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs1793257-A	Twin Study	Research Support, N.I.H., Extramural	T
11	132882997	rs11223321	A	C	rs11223321	21314694	4.17E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
11	134727848	rs11224040	T	C	rs11224040	23089632	1.09E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	384792	rs525381	G	A	rs525381	20201924	8.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	558423	rs12372234	C	T	rs12372234	24277619	2.40E-05	NA	0.52	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
12	922408	rs10774464	C	T	rs10774464	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	926248	rs7963376	T	C	rs7963376	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	1022679	rs6413436	A	G	rs6413436	20201924	4.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	1022679	rs6413436	A	G	rs6413436	20201924	9.00E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	1022679	rs6413436	A	G	rs6413436	pha002892	8.95E-06	phs000125	1.49	[1.25-1.78]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	RAD52	intron	NM_134424
12	1888673	rs10161408	T	C	rs10161408	21314694	1.80E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	4031104	rs10848958	C	T	rs10848958	21314694	3.81E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	5074338	rs10849182	G	A	rs10849182	21314694	9.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	5600466	rs4074967	T	G	rs4074967	21529783	5.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	6127891	rs1800385	C	A	rs1800385	21314694	8.39E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	6139261	rs216318	A	C	rs216318	21314694	3.23E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	7996890	rs11056079	C	T	rs11056079	20201924	6.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	7996890	rs11056079	C	T	rs11056079	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8000336	rs7965203	T	G	rs7965203	20201924	3.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8000336	rs7965203	T	G	rs7965203	20201924	4.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8014041	rs1894829	A	G	rs1894829	20201924	6.20E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8014041	rs1894829	A	G	rs1894829	20201924	8.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8014041	rs1894829	A	G	rs1894829	pha002892	8.02E-05	phs000125	1.45	[1.20-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	SLC2A14	intron	NM_153449
12	8014041	rs1894829	A	G	rs1894829	pha002893	6.24E-05	phs000125	1.56	[1.25-1.92]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	SLC2A14	intron	NM_153449
12	8016925	rs11612319	G	A	rs11612319	20201924	4.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8016925	rs11612319	G	A	rs11612319	20201924	6.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8016925	rs11612319	G	A	rs11612319	pha002892	6.55E-05	phs000125	1.45	[1.20-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SLC2A14	intron	NM_153449
12	8016925	rs11612319	G	A	rs11612319	pha002893	4.41E-05	phs000125	1.59	[1.27-1.96]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SLC2A14	intron	NM_153449
12	8023276	rs10047605	G	T	rs10047605	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8023276	rs10047605	G	T	rs10047605	20201924	2.60E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	8023276	rs10047605	G	T	rs10047605	pha002893	2.60E-05	phs000125	1.61	[1.28-2.00]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SLC2A14	intron	NM_153449
12	8271102	rs4883071	A	G	rs4883071	21314694	9.78E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	8804572	rs10505737	C	A	rs10505737	21314694	4.59E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	9139282	rs7296295	G	A	rs7296295	24277619	2.24E-04	NA	0.96	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
12	10480508	rs4102739	A	G	rs4102739	21314694	3.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	10926357	rs10845212	C	T	rs10845212	21314694	6.94E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	11411923	rs11835196	C	T	rs11835196	20201924	8.99E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	11841117	rs205534	A	G	rs205534	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	12109505	rs2961557	A	C	rs2961557	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	12358524	rs12307111	C	A	rs12307111	21314694	4.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	12903582	rs11055041	T	A	rs11055041	21314694	4.41E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	15368198	rs7955309	T	C	rs7955309	20201924	4.73E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	15370878	rs767201	G	A	rs767201	20201924	3.39E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	15463296	rs6488769	C	T	rs6488769	20201924	6.85E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	17572242	rs1305295	G	A	rs1305295	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	17639821	rs10219728	A	G	rs10219728	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	17653834	rs10840729	G	A	rs10840729	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	21070137	rs10841707	T	A	rs10841707	21314694	9.75E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	21222880	rs7980084	A	G	rs7980084	20201924	6.89E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	22105568	rs10743428	T	C	rs10743428	21314694	4.72E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	23193102	rs3913141	G	A	rs3913141	19581569	9.73E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
12	23674257	rs10842176	G	A	rs10842176	23089632	4.91E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	24122931	rs11047179	C	T	rs11047179	24277619	4.24E-04	NA	0.42	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	SOX5
12	24129436	rs12229376	G	T	rs12229376	24277619	9.35E-04	NA	0.39	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	SOX5
12	24375601	rs1357251	T	C	rs1357251	20201924	7.65E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	24512037	rs550338	G	A	rs550338	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	24512037	rs550338	G	A	rs550338	20201924	8.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	24512037	rs550338	G	A	rs550338	pha002893	8.88E-05	phs000125	1.56	[1.25-1.96]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SOX5	intron	NM_152989
12	24560244	rs7309268	G	T	rs7309268	21314694	9.64E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	24784139	rs4246224	G	A	rs4246224	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	25180058	rs11047768	G	A	rs11047768	24277619	6.65E-04	NA	0.44	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	LOC645177
12	25659672	rs10771224	T	C	rs10771224	21314694	5.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	26536761	rs11614384	T	C	rs11614384	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	27959905	rs7311374	C	T	rs7311374	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	28085129	rs7137085	G	A	rs7137085	20201924	3.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	28085129	rs7137085	G	A	rs7137085	20201924	3.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	28085129	rs7137085	G	A	rs7137085	pha002893	3.38E-05	phs000125	1.57	[1.27-1.94]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
12	28515881	rs10506030	A	T	rs10506030	21314694	5.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	30968662	rs2114904	A	G	rs2114904	24277619	5.49E-04	NA	0.41	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
12	30983838	rs33153	A	C	rs33153	21529783	6.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	31310808	rs6487980	T	C	rs6487980	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	31310808	rs6487980	T	C	rs6487980	20201924	9.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	31311075	rs7953222	C	T	rs7953222	20201924	5.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	44927340	rs4768555	A	G	rs4768555	20201924	7.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	44930901	rs1552859	G	T	rs1552859	24277619	7.40E-04	NA	0.42	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NELL2
12	45597540	rs12231753	C	T	rs12231753	19581569	6.96E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
12	45646266	rs2052603	G	T	rs2052603	19581569	2.23E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
12	45669753	rs7138247	G	A	rs7138247	19581569	7.21E-06	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
12	45710230	rs7965430	A	G	rs7965430	19581569	2.02E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
12	47084893	rs12229299	C	G	rs12229299	21314694	8.36E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	49066940	rs7315319	T	C	rs7315319	20201924	5.84E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	49066940	rs7315319	T	C	rs7315319	pha002891	5.84E-05	phs000125	3.7	[1.96-7.14]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	KANSL2	intron	NM_017822
12	49069636	rs2898086	T	C	rs2898086	20201924	1.34E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	49099850	rs7297499	T	C	rs7297499	20201924	5.97E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	49099850	rs7297499	T	C	rs7297499	pha002891	5.97E-05	phs000125	3.33	[1.85-6.25]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	CCNT1	intron	NM_001240
12	49714103	rs4898519	A	G	rs4898519	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	51616582	rs10747608	A	G	rs10747608	21314694	8.51E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	53069014	rs14024	T	C	rs14024	20201924	2.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	53069014	rs14024	T	C	rs14024	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	53069014	rs14024	T	C	rs14024	pha002893	2.86E-05	phs000125	1.07	[0.88-1.30]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	KRT1	missense	NM_006121
12	53173073	rs7397684	A	G	rs7397684	20201924	2.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	53173073	rs7397684	A	G	rs7397684	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	53173073	rs7397684	A	G	rs7397684	pha002893	2.09E-05	phs000125	1.63	[1.30-2.04]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	KRT76	nearGene-5	NM_015848
12	54450876	rs11170792	G	A	rs11170792	20201924	7.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	55343628	rs2252795	A	G	rs2252795	21314694	8.32E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	57917525	rs1148556	C	T	rs1148556	20201924	2.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	57938081	rs775238	C	T	rs775238	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	57942305	rs703841	T	G	rs703841	20201924	1.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	57942972	rs1148552	C	T	rs1148552	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	57945860	rs1148551	G	A	rs1148551	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	57946477	rs6581146	C	T	rs6581146	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	57953244	rs2600003	A	C	rs2600003	20201924	1.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	58167788	rs10877015	A	G	rs10877015	24277619	4.60E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	METTL21B
12	63114510	rs342171	T	C	rs342171	21314694	4.09E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	63167945	rs12303266	C	T	rs12303266	21703634	7.49E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
12	63305683	rs7967481	G	T	rs7967481	21314694	2.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	64597327	rs12581277	T	C	rs12581277	21314694	8.51E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	69162243	rs12321570	T	C	rs12321570	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	69334985	rs1144962	A	G	rs1144962	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	69334985	rs1144962	A	G	rs1144962	20201924	9.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	69341025	rs1195812	A	G	rs1195812	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	69432620	rs3925053	A	G,T	rs3925053	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	69432620	rs3925053	A	G,T	rs3925053	20201924	8.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	69744014	rs1800973	C	A	rs1800973	19581569	9.46E-07	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
12	70691305	rs11178177	C	T	rs11178177	21314694	8.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	71249996	rs12229663	A	G	rs12229663	24277619	4.29E-04	NA	0.45	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	PTPRR
12	76270756	rs1623319	G	A	rs1623319	21529783	9.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	76291888	rs7314267	G	A	rs7314267	21529783	4.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	76352699	rs3860052	T	G	rs3860052	21314694	9.59E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	77077098	rs17200717	T	C	rs17200717	21314694	3.98E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	77449514	rs10506725	T	C	rs10506725	21314694	9.24E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	77806686	rs4761378	T	C	rs4761378	21529783	3.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	78958896	rs1357096	G	A	rs1357096	20201924	8.18E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	79093237	rs487651	T	G	rs487651	24277619	2.47E-04	NA	0.63	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
12	80093317	rs2463107	A	C	rs2463107	21529783	7.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	82394154	rs1347222	T	C	rs1347222	21529783	3.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	82404500	rs7961308	T	C	rs7961308	21529783	4.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	83040610	rs12822754	A	G	rs12822754	21314694	6.40E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	83071648	rs4254133	C	T	rs4254133	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	83089431	rs12579483	T	C	rs12579483	23089632	1.86E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	83108395	rs4620789	G	T	rs4620789	23089632	9.63E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	87242122	rs4509845	A	G	rs4509845	21314694	6.87E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	87464274	rs1344791	C	T	rs1344791	21529783	3.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	88463451	rs2471503	T	C	rs2471503	21314694	7.05E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	88643302	rs11104778	C	G	rs11104778	21314694	6.21E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	92319215	rs4356270	G	A	rs4356270	20201924	3.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92319215	rs4356270	G	A	rs4356270	20201924	4.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92319215	rs4356270	G	A	rs4356270	23691058	0.00000842	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	92319215	rs4356270	G	A	rs4356270	pha002892	4.44E-05	phs000125	1.43	[1.20-1.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
12	92322558	rs4499040	G	A	rs4499040	20201924	4.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92322558	rs4499040	G	A	rs4499040	20201924	6.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92322558	rs4499040	G	A	rs4499040	pha002892	6.57E-05	phs000125	1.41	[1.19-1.67]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
12	92323972	rs12427267	A	G	rs12427267	20201924	2.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92323972	rs12427267	A	G	rs12427267	23691058	0.0000006	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	92325420	rs4842798	T	C	rs4842798	20201924	4.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92326500	rs11106345	T	C	rs11106345	20201924	3.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92326500	rs11106345	T	C	rs11106345	20201924	6.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92326500	rs11106345	T	C	rs11106345	23691058	0.00000722	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	92326500	rs11106345	T	C	rs11106345	pha002892	6.02E-05	phs000125	1.41	[1.19-1.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
12	92331588	rs10745574	A	G	rs10745574	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92336694	rs10777357	A	G	rs10777357	20201924	4.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92338833	rs4542452	C	A	rs4542452	20201924	5.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92353751	rs10777366	C	A	rs10777366	20201924	9.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92359839	rs7132890	G	A	rs7132890	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92368093	rs11106374	T	C	rs11106374	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	92370206	rs10859259	C	T	rs10859259	20201924	5.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	93049689	rs10859354	T	C	rs10859354	20201924	6.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	93972870	rs17021323	A	G	rs17021323	21314694	8.54E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	94672002	rs4761601	G	A	rs4761601	19581569	4.05E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
12	94729577	rs4761605	C	T	rs4761605	19581569	1.64E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
12	94741706	rs7138291	T	C	rs7138291	19581569	5.70E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
12	97321211	rs249571	C	T	rs249571	20201924	7.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	99490760	rs2372644	T	G	rs2372644	24277619	6.80E-04	NA	0.41	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	ANKS1B
12	99520594	rs17367186	T	G	rs17367186	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	99676996	rs11109794	G	A	rs11109794	21314694	9.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	101666017	rs703717	A	G	rs703717	24962325	6.70E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs703717-A	Research Support, N.I.H., Extramural	A,G	NA
12	101667827	rs703720	G	T	rs703720	24962325	7.49E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs703720-G	Research Support, N.I.H., Extramural	A	NA
12	101669016	rs2651251	C	T	rs2651251	24962325	7.49E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2651251-C	Research Support, N.I.H., Extramural	T	NA
12	101670656	rs824310	T	A	rs824310	24962325	7.49E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs824310-T	Research Support, N.I.H., Extramural	A	NA
12	101674285	rs703711	G	C	rs703711	24962325	8.41E-06	NA	1.35	[1.21-1.49]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs703711-G	Research Support, N.I.H., Extramural	C	UTP20
12	101685422	rs844030	G	A	rs844030	24962325	7.68E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs844030-G	Research Support, N.I.H., Extramural	T	UTP20
12	101688045	rs11608415	C	T	rs11608415	24962325	5.93E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11608415-T	Research Support, N.I.H., Extramural	C	UTP20
12	101690217	rs7296572	C	T	rs7296572	24962325	6.35E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7296572-T	Research Support, N.I.H., Extramural	C	UTP20
12	101705178	rs1472556	C	A	rs1472556	24962325	6.35E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1472556-A	Research Support, N.I.H., Extramural	G	UTP20
12	101715202	rs55721648	C	A	rs55721648	24962325	7.23E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs55721648-A	Research Support, N.I.H., Extramural	C	UTP20
12	101724081	rs7973083	T	A	rs7973083	24962325	5.53E-08	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7973083-A	Research Support, N.I.H., Extramural	T	UTP20
12	101729282	rs1814577	A	G	rs1814577	24962325	5.21E-08	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1814577-G	Research Support, N.I.H., Extramural	T,C	UTP20
12	101732655	rs56265469	C	T	rs56265469	24962325	1.25E-07	NA	1.33	[1.23-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs56265469-T	Research Support, N.I.H., Extramural	C	UTP20
12	101734684	rs7977587	A	G	rs7977587	24962325	1.66E-07	NA	1.32	[1.22-1.42]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7977587-G	Research Support, N.I.H., Extramural	A	UTP20
12	101736381	rs2270861	A	G	rs2270861	24962325	6.79E-08	NA	1.33	[1.23-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2270861-G	Research Support, N.I.H., Extramural	A	UTP20
12	101739860	rs3782848	G	A	rs3782848	24962325	6.31E-06	NA	1.31	[1.19-1.43]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs3782848-A	Research Support, N.I.H., Extramural	C	UTP20
12	101742180	rs57083693	T	C	rs57083693	24962325	4.00E-08	NA	1.35	[1.23-1.47]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs57083693-C	Research Support, N.I.H., Extramural	T	UTP20
12	101753954	rs10507130	G	A	rs10507130	24962325	1.20E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10507130-A	Research Support, N.I.H., Extramural	G	UTP20
12	101754920	rs11609516	C	G	rs11609516	24962325	1.20E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11609516-G	Research Support, N.I.H., Extramural	C	UTP20
12	101755683	rs7313312	T	C	rs7313312	23089632	1.03E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	101755683	rs7313312	T	C	rs7313312	24962325	1.20E-07	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7313312-C	Research Support, N.I.H., Extramural	T	UTP20
12	101944178	rs7299475	A	G	rs7299475	21314694	7.47E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	104664093	rs10861184	A	G	rs10861184	19581569	9.18E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
12	105561991	rs10861359	C	A	rs10861359	21314694	7.67E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	105827413	rs10746034	C	T	rs10746034	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	105827413	rs10746034	C	T	rs10746034	20201924	6.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	105833967	rs2082371	A	G	rs2082371	20201924	1.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	105833967	rs2082371	A	G	rs2082371	20201924	2.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	108798873	rs11113857	T	C	rs11113857	20201924	2.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	108803755	rs17040470	G	A	rs17040470	20201924	1.55E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	111331016	rs11065750	G	A	rs11065750	24277619	3.00E-05	NA	0.58	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A,G	CCDC63
12	111334117	rs1858881	T	C	rs1858881	24277619	1.80E-05	NA	0.6	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	CCDC63
12	111340243	rs10774610	T	C	rs10774610	24277619	1.80E-05	NA	0.6	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	NA	CCDC63
12	111692124	rs4766453	C	T	rs4766453	24277619	1.39E-06	NA	0.58	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	CUX2
12	111698457	rs6490029	G	A	rs6490029	24277619	1.33E-04	NA	0.51	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	CUX2
12	111706877	rs4766566	C	T	rs4766566	24277619	2.60E-05	NA	0.57	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	CUX2
12	112110489	rs3782886	T	C	rs3782886	24277619	4.55E-08	NA	0.89	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	BRAP
12	112241766	rs671	G	A	rs671	24277619	5.00E-08	NA	0.88	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ALDH2
12	113982522	rs11066595	C	G	rs11066595	21314694	6.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	114463587	rs898078	G	A	rs898078	21529783	2.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	114615807	rs7971457	T	C	rs7971457	24277619	7.17E-04	NA	0.73	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
12	117475178	rs1875144	T	C	rs1875144	21703634	9.37E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
12	117565281	rs6490111	G	T	rs6490111	20201924	5.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	117718822	rs2293050	C	T	rs2293050	21529783	8.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	118134939	rs7303368	C	T	rs7303368	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	118467645	rs5745879	C	T	rs5745879	21314694	2.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	118896470	rs7316050	A	T	rs7316050	21314694	4.78E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	120236754	rs203339	T	C	rs203339	21529783	8.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	121404056	rs7303401	T	A	rs7303401	21314694	1.48E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	121442199	rs3751151	T	A	rs3751151	21314694	2.74E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	125158762	rs11057750	A	G	rs11057750	24277619	7.59E-04	NA	0.4	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
12	125460667	rs4580006	T	A	rs4580006	21314694	2.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
12	126253507	rs1558062	G	A	rs1558062	20201924	6.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	126444520	rs10847023	T	C	rs10847023	20201924	2.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	126444520	rs10847023	T	C	rs10847023	20201924	8.40E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	126444520	rs10847023	T	C	rs10847023	pha002893	8.38E-05	phs000125	1.72	[1.31-2.26]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	LOC400084	intron	NR_034132
12	127629984	rs10847282	C	T	rs10847282	20201924	1.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	127629984	rs10847282	C	T	rs10847282	pha002892	1.39E-05	phs000125	1.69	[1.33-2.17]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
12	129158367	rs7960753	A	C	rs7960753	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129158367	rs7960753	A	C	rs7960753	20201924	4.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129161625	rs11608979	G	A	rs11608979	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129161625	rs11608979	G	A	rs11608979	20201924	1.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129163648	rs10773566	G	T	rs10773566	20201924	1.70E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129163648	rs10773566	G	T	rs10773566	20201924	7.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129163648	rs10773566	G	T	rs10773566	pha002892	7.52E-05	phs000125	1.42	[1.19-1.68]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	TMEM132C	intron	NM_001136103
12	129163648	rs10773566	G	T	rs10773566	pha002893	1.68E-05	phs000125	1.55	[1.27-1.89]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	TMEM132C	intron	NM_001136103
12	129166145	rs1489430	T	C	rs1489430	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129166145	rs1489430	T	C	rs1489430	20201924	5.10E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129166145	rs1489430	T	C	rs1489430	pha002893	5.09E-05	phs000125	1.49	[1.23-1.81]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	TMEM132C	intron	NM_001136103
12	129167872	rs6486717	T	G	rs6486717	20201924	2.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129167872	rs6486717	T	G	rs6486717	20201924	6.90E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	129167872	rs6486717	T	G	rs6486717	pha002893	6.89E-05	phs000125	1.5	[1.23-1.83]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	TMEM132C	intron	NM_001136103
12	129804154	rs11060247	C	T	rs11060247	20201924	7.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
12	131202035	rs10848190	C	T	rs10848190	23691058	0.00000543	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	131455221	rs4759814	T	G	rs4759814	23942779	9.60E-06	NA	0.74	[NA] unit increase	7,188 European ancestry individuals	European(7188)	ALL(7188)	EUR(7188)	ALL(7188)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs4759814-A	Twin Study	Research Support, N.I.H., Extramural	T
12	132154193	rs12832187	C	T	rs12832187	21314694	2.94E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	20798240	rs877098	A	G	rs877098	21314694	5.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	21188339	rs9506528	G	A	rs9506528	20201924	7.63E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	22304216	rs670821	C	T	rs670821	21529783	9.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	23755127	rs4770403	G	A	rs4770403	22004471	6.00E-06	NA	1.33	[1.17-1.50]	1,333 European ancestry cases; 2,168 European ancestry controls	European(3501)	ALL(3501)	EUR(3501)	ALL(3501)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
13	23957514	rs17078678	C	A	rs17078678	20201924	1.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	23984431	rs17078717	A	G	rs17078717	20201924	5.55E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	24255790	rs4769281	A	G	rs4769281	21314694	6.11E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	24658356	rs9805786	G	T	rs9805786	20201924	4.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	24658356	rs9805786	G	T	rs9805786	20201924	8.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	24659726	rs736081	T	C	rs736081	20201924	1.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	24659726	rs736081	T	C	rs736081	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	24718406	rs7982678	G	A	rs7982678	20201924	4.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	25784082	rs9581297	G	T	rs9581297	21314694	2.08E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	25996690	rs13378890	C	T	rs13378890	21314694	9.90E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	26262180	rs17685787	A	G	rs17685787	21314694	7.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	26510069	rs184249	G	A	rs184249	24277619	8.72E-04	NA	0.45	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	ATP8A2
13	26516460	rs1324408	A	G	rs1324408	24277619	2.46E-04	NA	0.48	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	ATP8A2
13	27586873	rs9512491	G	C	rs12020569	21314694	5.00E-06	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs12020569-C	Research Support, N.I.H., Extramural
13	27586873	rs9512491	G	C	rs9512491	21314694	5.00E-06	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	27748294	rs7336237	A	G	rs7336237	20201924	6.96E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	27910122	rs2094497	T	C	rs2094497	21529783	1.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	27920611	rs9512637	T	C	rs9512637	21529783	1.00E-07	NA	0.11	[NA] unit decrease	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs9512637-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	28377139	rs927848	A	G	rs927848	20201924	7.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	28584744	rs17086213	T	C	rs17086213	21314694	9.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	28586220	rs7317159	T	C	rs7317159	21314694	1.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	29101681	rs9550377	C	T	rs9550377	21314694	7.72E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	29152505	rs9508066	G	A	rs9508066	21314694	6.43E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	31512154	rs17600802	T	C	rs17600802	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	31726178	rs4943157	T	C	rs4943157	21314694	6.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	32635763	rs456053	G	A	rs456053	21314694	4.68E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	33387246	rs990324	A	G	rs990324	21529783	2.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	36535192	rs9545925	G	T	rs9545925	20201924	3.43E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	36696494	rs6563354	C	T	rs6563354	20201924	3.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	37347977	rs3897230	C	T	rs3897230	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	37350679	rs7322307	A	G	rs7322307	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	37458139	rs576434	T	C	rs576434	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	38512532	rs9548113	T	C	rs9548113	21314694	2.20E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	42196943	rs7981912	G	A	rs7981912	21314694	4.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	42560772	rs11620406	C	T	rs11620406	21529783	7.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
13	43798348	rs2289774	T	C	rs2289774	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	43815123	rs10507519	C	T	rs10507519	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	43859324	rs12874803	T	C	rs12874803	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	43883604	rs12857536	G	T	rs12857536	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	44000631	rs1323161	G	A	rs1323161	24277619	6.70E-05	NA	0.72	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ENOX1
13	44085945	rs3884613	T	C	rs3884613	20201924	7.95E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	46754734	rs372540087	TAGA	T	rs9567638	20201924	1.93E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	46754734	rs9567638	T	C	rs9567638	20201924	1.93E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	46785521	rs912784	C	A	rs912784	20201924	3.16E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	48628449	rs9595835	T	C	rs9595835	21314694	2.44E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	48666690	rs9316348	G	A	rs9316348	21314694	3.07E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	53359285	rs235786	C	T	rs235786	20201924	2.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	53359285	rs235786	C	T	rs235786	20201924	6.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	53359412	rs9536287	G	A	rs9536287	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	53359412	rs9536287	G	A	rs9536287	20201924	7.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	53527973	rs2208989	C	T	rs2208989	24277619	6.20E-04	NA	1.02	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
13	53543167	rs17053117	G	A	rs17053117	24277619	4.37E-04	NA	0.6	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
13	54915506	rs952766	G	A	rs952766	20201924	5.75E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	55795115	rs12857116	T	G	rs12857116	20201924	7.61E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	55836730	rs4146540	A	G	rs4146540	20201924	5.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	55853051	rs9537050	A	G	rs9537050	20201924	5.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	55861155	rs9316778	T	C	rs9316778	20201924	5.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	55921859	rs9597162	G	A	rs9597162	20201924	4.75E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	56019891	rs9597180	A	G	rs9597180	20201924	1.41E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	56109172	rs9597202	A	G	rs9597202	20201924	3.86E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	58033551	rs6561934	C	T	rs6561934	24962325	5.22E-06	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs6561934-T	Research Support, N.I.H., Extramural	C	NA
13	58033793	rs7338789	T	A	rs7338789	24962325	5.22E-06	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7338789-A	Research Support, N.I.H., Extramural	T	NA
13	58033890	rs7337578	C	T	rs7337578	24962325	6.59E-06	NA	1.34	[1.22-1.46]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7337578-T	Research Support, N.I.H., Extramural	T	NA
13	58040592	rs57558300	A	G	rs57558300	24962325	5.68E-06	NA	1.36	[1.22-1.50]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs57558300-G	Research Support, N.I.H., Extramural	A	NA
13	58049234	rs7984728	C	G	rs7984728	24962325	5.47E-06	NA	1.36	[1.22-1.50]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7984728-G	Research Support, N.I.H., Extramural	C	NA
13	58054783	rs11841410	A	C	rs11841410	24962325	5.47E-06	NA	1.36	[1.22-1.50]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11841410-C	Research Support, N.I.H., Extramural	A	NA
13	58054941	rs11840139	T	C	rs11840139	24962325	5.47E-06	NA	1.36	[1.22-1.50]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11840139-C	Research Support, N.I.H., Extramural	T	NA
13	58085565	rs61116530	T	C	rs61116530	24962325	5.94E-06	NA	1.36	[1.22-1.50]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs61116530-C	Research Support, N.I.H., Extramural	T	NA
13	58090211	rs7997918	A	C	rs7997918	24962325	5.94E-06	NA	1.36	[1.22-1.50]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs7997918-C	Research Support, N.I.H., Extramural	A	NA
13	58114748	rs11840092	T	C	rs11840092	24962325	2.00E-06	NA	1.37	[1.23-1.51]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs11840092-C	Research Support, N.I.H., Extramural	T	NA
13	59348264	rs7333252	T	C	rs7333252	24277619	1.77E-04	NA	0.6	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
13	59727520	rs7991723	C	T	rs7991723	24277619	9.09E-04	NA	0.46	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
13	60990506	rs4886227	A	G	rs4886227	20201924	1.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	60990506	rs4886227	A	G	rs4886227	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	61035798	rs9538710	G	A	rs9538710	20201924	7.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	61035798	rs9538710	G	A	rs9538710	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	61109963	rs9538740	A	G	rs9538740	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	61109963	rs9538740	A	G	rs9538740	20201924	2.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	61119357	rs12865240	A	G	rs12865240	20201924	7.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	61119357	rs12865240	A	G	rs12865240	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	62048616	rs2997415	G	A	rs2997415	20201924	2.28E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	64232341	rs1530485	C	T	rs1530485	20201924	5.78E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	64232341	rs1530485	C	T	rs1530485	20202923	3.52E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	64242114	rs2810864	G	A	rs2810864	20201924	7.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	64242114	rs2810864	G	A	rs2810864	20202923	9.00E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	66908399	rs1982305	G	A	rs1982305	21314694	5.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	67521014	rs17791001	A	C	rs17791001	20202923	5.40E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	67523258	rs9540953	T	C	rs9540953	20202923	3.42E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	68825070	rs1146833	C	T	rs1146833	20201924	5.25E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	70948065	rs17086945	T	C	rs17086945	20201924	1.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	70948065	rs17086945	T	C	rs17086945	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	70969302	rs7317253	T	G	rs7317253	20201924	2.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	70969302	rs7317253	T	G	rs7317253	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	70969302	rs7317253	T	G	rs7317253	pha002892	2.51E-05	phs000125	2.27	[1.56-3.33]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
13	71136143	rs9542387	G	A	rs9542387	20201924	4.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	71137148	rs9529776	G	A	rs9529776	20201924	2.24E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	71242767	rs1495858	G	A	rs1495858	20201924	6.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	71343278	rs6562646	C	A	rs6562646	20201924	6.83E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	71346319	rs4471563	T	C	rs4471563	20201924	1.67E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	71358187	rs2769493	G	A	rs2769493	20201924	2.12E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	71368970	rs2769490	T	C	rs2769490	20201924	3.43E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	72342436	rs17088471	C	A	rs17088471	21314694	2.63E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	74530279	rs9318232	T	C	rs9318232	20201924	1.58E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	74538020	rs9318238	T	C	rs9318238	20201924	4.25E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	74539068	rs2875670	A	G	rs2875670	20201924	5.45E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	76516894	rs1538901	T	C	rs1538901	20201924	3.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	77063531	rs493863	A	G	rs493863	20201924	2.96E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	77065032	rs433780	C	T	rs433780	20201924	8.36E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	78025986	rs4489889	C	T	rs4489889	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	78025986	rs4489889	C	T	rs4489889	20201924	7.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	81355623	rs9318714	G	A	rs9318714	20201924	1.78E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	81419379	rs2329172	G	A	rs2329172	20201924	3.14E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	82141621	rs9593569	G	A	rs9593569	20201924	1.42E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	82300981	rs261446	T	C	rs261446	20201924	8.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	85456392	rs17078679	A	G	rs17078679	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	86114450	rs9547256	T	G	rs9547256	20201924	2.28E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	86615348	rs7983827	G	A	rs7983827	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	86620040	rs9576007	G	A	rs9576007	20201924	6.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	86729008	rs9576027	A	G	rs9576027	24277619	3.28E-04	NA	0.65	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
13	95761886	rs16950632	G	A	rs16950632	20201924	6.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	95849680	rs4148478	A	G	rs4148478	21314694	7.57E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	97978485	rs1556086	A	G	rs1556086	21529783	2.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
13	98016416	rs9556711	G	A	rs9556711	21529783	2.00E-06	NA	0.16	[NA] unit decrease	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol use disorder factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D019973	Alcohol-Related Disorders	NA	NA	Drug abuse	rs9556711-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	98016416	rs9556711	G	A	rs9556711	21529783	8.00E-07	NA	0.17	[NA] unit decrease	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol dependence factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs9556711-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
13	98192735	rs184729	A	C	rs184729	21314694	7.55E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	100898529	rs681561	A	C	rs681561	21314694	3.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	102162080	rs9518426	C	T	rs9518426	20201924	1.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	102291577	rs9554813	A	G	rs9554813	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	102291577	rs9554813	A	G	rs9554813	20201924	3.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	102627599	rs7324177	G	A	rs7324177	20201924	3.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	102836774	rs7322577	T	G	rs7322577	20201924	4.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	106831787	rs9587100	A	G	rs9587100	21703634	1.92E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
13	107360401	rs9587180	A	G	rs9587180	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	109785845	rs919597	C	T	rs919597	20201924	4.56E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	109957290	rs4134382	T	C	rs4134382	21314694	8.26E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	110325749	rs6492218	C	T	rs6492218	21956439	3.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
13	111980478	rs2479955	A	G	rs2479955	20201924	4.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
13	111981399	rs2479956	T	C	rs2479956	20201924	5.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	20497737	rs7141391	A	C,G,T	rs7141391	20201924	2.79E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	24760009	rs4568	G	A	rs4568	20201924	4.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	24760255	rs2295310	C	T	rs2295310	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	25272926	rs9323560	G	A	rs9323560	21314694	3.54E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	28119601	rs10130248	A	G	rs10130248	24277619	4.61E-04	NA	0.46	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	LOC728755
14	33868380	rs17101003	G	A	rs17101003	21314694	6.85E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	33869876	rs17571355	A	C	rs17571355	pha002893	2.92E-05	phs000125	1.96	[1.43-2.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NPAS3	intron	NM_022123
14	35862404	rs7152826	C	A	rs7152826	24277619	3.87E-04	NA	0.46	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
14	41315945	rs1349568	A	C	rs1349568	20201924	2.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	41405093	rs12890528	C	T	rs12890528	21956439	7.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	41433306	rs1176968	G	A	rs1176968	21956439	9.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	41440331	rs12889050	C	T	rs12889050	21956439	7.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	42498031	rs1684716	T	G	rs1684716	21529783	6.80E-06	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	42511847	rs1632694	C	T	rs1632694	21529783	6.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	42548257	rs1684693	T	G	rs1684693	21529783	4.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
14	42548912	rs1542668	A	G	rs1542668	21529783	2.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
14	42634072	rs8006978	G	T	rs8006978	21529783	2.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	42644617	rs10135407	A	G	rs10135407	21529783	2.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	42655275	rs2154294	A	G	rs2154294	21529783	3.00E-06	NA	0.08	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (12-month weekly alcohol consumption)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs2154294-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
14	42907447	rs7157217	C	T	rs7157217	20201924	8.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	42909013	rs17113034	T	C	rs17113034	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	45110153	rs12896581	C	A	rs12896581	20201924	5.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	45188966	rs17115444	T	C	rs17115444	20201924	2.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	45189702	rs17115446	T	C	rs17115446	20201924	4.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	45415597	rs11848799	T	C	rs11848799	21314694	1.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	46232854	rs1266294	A	C	rs1266294	21529783	7.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
14	46241497	rs1686312	G	T	rs1686312	21529783	9.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	46268185	rs4900680	A	G	rs4900680	21529783	8.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	49868900	rs7148751	G	A	rs7148751	20201924	8.08E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	52621668	rs941612	A	G	rs941612	21529783	7.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	52768564	rs8008292	T	C	rs8008292	20201924	2.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	52768564	rs8008292	T	C	rs8008292	20201924	4.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	53046601	rs4901286	G	A	rs4901286	20201924	3.29E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	53094595	rs1007894	G	A	rs1007894	24277619	7.84E-04	NA	0.6	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	GPR137C
14	54072858	rs1380131	C	T	rs1380131	21529783	9.00E-06	NA	0.15	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs1380131-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	55194464	rs11845379	T	C	rs11845379	21314694	8.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	57033076	rs11623335	G	A	rs11623335	21956439	3.00E-07	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	57899894	rs7144713	T	C	rs7144713	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	59296184	rs442555	T	C	rs442555	21529783	9.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	61874448	rs767755	G	A	rs767755	24277619	1.49E-04	NA	0.58	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	PRKCH
14	61937801	rs10483734	T	C	rs10483734	19581569	1.20E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
14	64191750	rs11845765	T	G	rs11845765	20201924	1.62E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	64408108	rs2275019	G	C	rs2275019	21314694	5.68E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	65499450	rs7148144	G	A	rs7148144	20201924	6.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	65499450	rs7148144	G	A	rs7148144	20201924	6.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	65646445	rs7141753	C	T	rs7141753	21314694	3.81E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	65653895	rs1760981	T	G	rs1760981	20201924	5.38E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	65767333	rs1269068	C	T	rs1269068	19581569	4.05E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
14	67029033	rs7159831	G	A	rs7159831	20201924	8.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	70578699	rs1035717	A	G	rs1035717	23691058	0.00000636	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	70580236	rs4902778	C	T	rs4902778	21314694	2.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	70754807	rs2877626	A	G	rs2877626	21314694	6.17E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	71352648	rs36563	T	G	rs36563	19581569	5.00E-06	NA	1.33	[1.18-1.50]	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs36563-A	Multicenter Study	Research Support, Non-U.S. Gov't	C
14	71395604	rs2810114	C	A	rs2810114	22004471	4.00E-06	NA	1.29	[1.16-1.44]	1,333 European ancestry cases; 2,168 European ancestry controls	European(3501)	ALL(3501)	EUR(3501)	ALL(3501)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
14	71654121	rs8016108	C	T	rs8016108	20201924	5.02E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	72882397	rs11158954	C	T	rs11158954	24277619	9.35E-04	NA	0.44	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	RGS6
14	73071503	rs2803953	C	T	rs2803953	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	73071503	rs2803953	C	T	rs2803953	20201924	8.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	73107771	rs2526919	A	G	rs2526919	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	78351762	rs17753195	G	A	rs17753195	21314694	5.14E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	78363932	rs17106558	G	A	rs17106558	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	78555941	rs4903705	C	T	rs4903705	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	78557505	rs10483889	T	G	rs10483889	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	78557505	rs10483889	T	G	rs10483889	20201924	8.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	78615593	rs4903712	T	C	rs4903712	23691058	0.00000167	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
14	78622523	rs17754467	A	G	rs17754467	20201924	1.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	78622523	rs17754467	A	G	rs17754467	20201924	2.70E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	78622523	rs17754467	A	G	rs17754467	23691058	0.000000554	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	78622523	rs17754467	A	G	rs17754467	pha002892	1.55E-05	phs000125	1.56	[1.27-1.89]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
14	78622523	rs17754467	A	G	rs17754467	pha002893	2.71E-05	phs000125	1.67	[1.32-2.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
14	84180364	rs1958420	T	G	rs1958420	20201924	8.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	84180869	rs10873350	G	A	rs10873350	20201924	8.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	84182662	rs9323737	A	G	rs9323737	20201924	8.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	84192245	rs877800	C	T	rs877800	20201924	8.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	86691435	rs12437116	T	C	rs12437116	20201924	7.83E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	88645857	rs7157457	C	T	rs7157457	24277619	6.95E-04	NA	0.62	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
14	90636206	rs7149330	G	A	rs7149330	22096494	8.50E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
14	91247477	rs8012052	A	G	rs8012052	21314694	1.95E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	92556055	rs17807815	T	C	rs17807815	21314694	3.48E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	94934176	rs12892340	G	A	rs12892340	21314694	8.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	95207147	rs2896294	T	C	rs2896294	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	95477759	rs7148434	A	G	rs7148434	21314694	9.15E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	97057998	rs7149784	G	A	rs7149784	20201924	5.38E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	99053053	rs8005917	T	C	rs8005917	23089632	1.70E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
14	99053964	rs4905720	A	G	rs4905720	23089632	3.86E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
14	104062068	rs2403199	A	C	rs2403199	20201924	4.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
14	105386149	rs2841269	G	C	rs2841269	21314694	3.69E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	105402418	rs10083490	C	T	rs10083490	21314694	6.95E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
14	105457161	rs10133292	T	C	rs10133292	21314694	3.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	32299953	rs1567887	C	T	rs1567887	20201924	3.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	32299953	rs1567887	C	T	rs1567887	20201924	4.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	32373693	rs7179733	C	T	rs7179733	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	33688687	rs17236010	C	T	rs17236010	21314694	9.61E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	33794552	rs4144333	A	G	rs4144333	19581569	1.96E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
15	33892297	rs16973062	T	C	rs16973062	20201924	4.62E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	33896191	rs1565937	C	T	rs1565937	20201924	1.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	34421951	rs11639310	C	T	rs11639310	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	36520994	rs35852281	C	T	rs35852281	20201924	8.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	36548888	rs16962759	T	C	rs16962759	20201924	6.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	36548888	rs16962759	T	C	rs16962759	20201924	8.30E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	36548888	rs16962759	T	C	rs16962759	pha002892	6.38E-05	phs000125	1.64	[1.28-2.08]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
15	36548888	rs16962759	T	C	rs16962759	pha002893	8.28E-05	phs000125	1.79	[1.33-2.38]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
15	37212897	rs837136	G	A	rs837136	21703634	4.22E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	38960882	rs7168475	A	C,G,T	rs7168475	23089632	0.00000198	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38960882	rs7168475	A	C,G,T	rs7168475	23089632	0.000466	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38962756	rs1874252	G	T	rs1874252	24962325	7.00E-06	NA	1.32	[1.20-1.44]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs1874252-G	Research Support, N.I.H., Extramural	C	NA
15	38986368	rs12912251	G	T	rs12912251	23089632	4.56E-08	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38986813	rs12898460	C	T	rs12898460	23089632	4.71E-08	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38988097	rs12903120	G	T	rs12903120	23089632	0.00000762	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38988097	rs12903120	G	T	rs12903120	23089632	5.45E-08	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38988107	rs35102843	C	A	rs35102843	23089632	4.55E-08	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38988391	rs7163869	G	C	rs7163869	23089632	9.32E-08	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38988760	rs7171233	T	A	rs7171233	23089632	8.45E-08	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38988815	rs7165988	C	G	rs7165988	23089632	0.000000097	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38989605	rs34356257	T	C	rs34356257	23089632	0.000000101	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38989657	rs34141940	G	A	rs34141940	23089632	0.000000107	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38989674	rs34281605	G	A	rs34281605	23089632	0.000000125	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38989770	rs35024396	G	A	rs35024396	23089632	0.000000123	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38990171	rs2172835	C	T	rs2172835	23089632	0.000000201	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38991520	rs12916379	A	G	rs12916379	23089632	0.000000174	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38991520	rs12916379	A	G	rs12916379	23089632	0.0000406	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38992547	rs2132157	A	G	rs2132157	23089632	0.000000192	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38992547	rs2132157	A	G	rs2132157	23089632	0.0000435	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38992893	rs12901215	G	A	rs12901215	23089632	0.000000438	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38995491	rs12899449	A	G	rs12899449	23089632	0.0000126	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38996981	rs7183893	A	C	rs7183893	23089632	0.00000082	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38998395	rs36094159	G	A	rs36094159	23089632	0.000000694	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	38998669	rs35795311	C	G	rs35795311	23089632	0.000000644	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	39622593	rs7181250	T	C	rs7181250	21314694	7.02E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	41006523	rs2412546	G	A	rs2412546	21314694	7.02E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	42190196	rs1672461	C	T	rs1672461	21314694	7.17E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	42434837	rs1356410	T	C	rs1356410	21529783	3.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
15	42991066	rs4924694	T	A	rs4924694	21314694	9.32E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	43042690	rs7166775	G	A	rs7166775	21314694	6.26E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	43074680	rs12915116	C	T	rs12915116	21314694	2.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	44582886	rs8024461	G	A	rs8024461	21703634	3.17E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	44674840	rs11856569	A	C	rs11856569	21703634	1.48E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	44821843	rs2556560	A	G	rs2556560	21703634	1.77E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	44943757	rs3759871	A	G	rs3759871	21703634	2.46E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	49011049	rs2413913	C	T	rs2413913	21314694	7.42E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	49075918	rs11631496	T	C	rs11631496	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	49253961	rs8031813	C	A	rs8031813	24277619	6.81E-04	NA	0.53	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	SHC4
15	50352887	rs8024393	A	G	rs8024393	21314694	3.35E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	50477235	rs1365507	A	G	rs1365507	21314694	6.89E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	51901605	rs6493511	A	G	rs6493511	21314694	9.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	52997976	rs2433285	T	C	rs2433285	21314694	3.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	54476135	rs8036265	G	A	rs8036265	20201924	6.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	54476135	rs8036265	G	A	rs8036265	20201924	6.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	54974499	rs2414358	T	A	rs2414358	21314694	9.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	55555602	rs4261468	A	G	rs4261468	20201924	5.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	55560425	rs11071175	A	G	rs11071175	20201924	7.65E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	56044189	rs2414433	T	C	rs2414433	21529783	1.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
15	57694938	rs12440459	C	T	rs12440459	21314694	6.76E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	57734187	rs8034838	G	C	rs8034838	21314694	3.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	57859727	rs7179379	C	T	rs7179379	20201924	5.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57873438	rs935549	C	T	rs935549	20201924	1.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57873438	rs935549	C	T	rs935549	20201924	3.90E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57873438	rs935549	C	T	rs935549	pha002892	3.91E-06	phs000125	1.5	[1.26-1.78]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
15	57878811	rs11071334	T	C	rs11071334	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57881889	rs744318	T	G	rs744318	20201924	2.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57881889	rs744318	T	G	rs744318	20201924	3.60E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57881889	rs744318	T	G	rs744318	pha002892	3.60E-06	phs000125	1.4	[0.86-2.28]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
15	57918574	rs17239999	C	T	rs17239999	20201924	8.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57934701	rs7176042	G	A	rs7176042	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57935419	rs2433196	A	C	rs2433196	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	57957314	rs1425948	A	G	rs1425948	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	58475125	rs11854297	T	C	rs11854297	21314694	5.15E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	59711691	rs10519005	C	T	rs10519005	24962325	5.00E-06	NA	1.26	[1.16-1.36]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs10519005-T	Research Support, N.I.H., Extramural	T	NA
15	59715666	rs7164726	C	T	rs7164726	20201924	5.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	59715666	rs7164726	C	T	rs7164726	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	59988472	rs12438078	G	C	rs12438078	21314694	2.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	60000239	rs10851664	G	C	rs10851664	21314694	7.59E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	61433543	rs11071587	G	A	rs11071587	21314694	8.71E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	62939440	rs938979	T	C	rs938979	pha002893	2.26E-05	phs000125	1.1	[0.88-1.37]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
15	62948909	rs12591037	C	T	rs12591037	pha002893	3.67E-05	phs000125	1.58	[1.27-1.96]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	TLN2	intron	NM_015059
15	63145902	rs16945949	G	A	rs16945949	20201924	5.12E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	63320534	rs12164904	C	G	rs12164904	21314694	9.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	66890484	rs2439353	C	G	rs2439353	21314694	2.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	69018959	rs17279860	A	T	rs17279860	21314694	8.32E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	69278546	rs4777102	C	T	rs4777102	21314694	1.67E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	70452945	rs8040467	A	C	rs8040467	21314694	4.28E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	70477904	rs2009403	A	G	rs2009403	20201924	6.07E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	70490503	rs10162898	G	A	rs10162898	20201924	6.63E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	70517708	rs16954296	C	T	rs16954296	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	70525659	rs7175167	C	T	rs7175167	20201924	3.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	71655735	rs12102112	C	T	rs12102112	21314694	6.43E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	72598614	rs2959930	G	A	rs2959930	21314694	8.91E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	75415962	rs2029519	A	G	rs2029519	23089632	1.07E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	75422131	rs4479194	G	A	rs4479194	23089632	0.00000527	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	75424593	rs7172677	A	C	rs7172677	23089632	0.00000715	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	75424593	rs7172677	A	C	rs7172677	23089632	0.000535	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	78578659	rs7173851	T	G	rs7173851	24277619	5.75E-04	NA	0.41	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	WDR61
15	79484083	rs8028654	T	G	rs8028654	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	79787835	rs4778700	A	G	rs4778700	21314694	9.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	79815143	rs11638410	G	A	rs11638410	20201924	3.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	79819871	rs1415571	G	T	rs1415571	20201924	8.11E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	80033885	rs443394	C	T	rs443394	23089632	4.66E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	80779758	rs4778800	T	G	rs4778800	20201924	5.53E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	81367809	rs16972726	T	C	rs16972726	21314694	3.49E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	85314054	rs12443381	G	A	rs12443381	21529783	5.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
15	85447060	rs11634491	A	G	rs11634491	20201924	6.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	85471281	rs4980343	C	T	rs4980343	20201924	5.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	85938651	rs16977810	C	A	rs16977810	20201924	8.54E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	85948709	rs13379803	C	T	rs13379803	20201924	4.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	85951446	rs11858860	T	C	rs11858860	20201924	1.39E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	86465715	rs11858797	T	C	rs11858797	20201924	8.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	87664390	rs10152646	C	T	rs10152646	20201924	1.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	87664390	rs10152646	C	T	rs10152646	20201924	7.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	88824681	rs894290	A	G	rs894290	20201924	3.03E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	88824681	rs894290	A	G	rs894290	pha002891	3.03E-05	phs000125	1.96	[1.43-2.69]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
15	91561182	rs3743445	C	T	rs3743445	20201924	3.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	91562005	rs8026678	A	G	rs8026678	20201924	6.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	92322122	rs4322641	C	T	rs4322641	21314694	1.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
15	93044339	rs8040009	T	C	rs8040009	21529783	3.00E-07	NA	0.12	[NA] unit decrease	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs8040009-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	94863837	rs4328383	T	G	rs4328383	24277619	7.29E-04	NA	1.06	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	MCTP2
15	94884980	rs3743307	G	A	rs3743307	24277619	4.28E-04	NA	4.77	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	MCTP2
15	94959409	rs10520754	C	T	rs10520754	20201924	7.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	94960355	rs1368839	T	G	rs1368839	20201924	4.98E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	95024760	rs1048048	T	C	rs1048048	20201924	2.66E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	96052742	rs933769	C	T	rs933769	21529783	7.00E-06	NA	0.1	[NA] unit decrease	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol dependence factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs933769-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
15	96637443	rs7171368	T	C	rs7171368	24277619	7.72E-04	NA	0.5	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
15	96646200	rs1036517	G	A	rs1036517	24277619	8.10E-05	NA	0.52	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
15	99072905	rs12719740	G	A	rs12719740	20201924	3.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	99084760	rs4641724	C	A	rs4641724	20201924	7.33E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	99256570	rs3803476	A	G	rs3803476	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	99267633	rs4966017	T	G	rs4966017	20201924	6.40E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	99267633	rs4966017	T	G	rs4966017	pha002891	6.40E-05	phs000125	2	[1.43-2.86]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	IGF1R	intron	NM_000875
15	101094130	rs113791767	C	CT	rs11634945	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	101094130	rs11634945	C	T	rs11634945	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	101112342	rs1493652	T	C	rs1493652	20201924	8.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	101115448	rs4965678	C	A	rs4965678	20201924	7.15E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
15	101493839	rs12911894	C	A	rs12911894	20201924	3.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	1997614	rs2252523	A	G	rs2252523	21314694	2.54E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	3094261	rs1004792	G	A	rs1004792	20201924	5.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	3094261	rs1004792	G	A	rs1004792	20201924	6.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	4079823	rs10775349	G	C	rs10775349	21314694	6.13E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	4168170	rs9927767	T	A	rs9927767	21314694	8.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	4250915	rs879151	C	A	rs879151	21314694	2.83E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	5951424	rs17138815	C	T	rs17138815	20201924	4.49E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	7842522	rs3862445	T	C	rs3862445	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	7854984	rs8058542	G	A	rs8058542	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	8590873	rs8061765	G	A	rs8061765	21314694	8.12E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	10177995	rs7206714	A	C	rs7206714	21314694	1.69E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	10327329	rs1097863	T	G	rs1097863	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	10815230	rs4780986	A	G	rs4780986	20201924	9.42E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	10815230	rs4780986	A	G	rs4780986	pha002891	9.42E-05	phs000125	1.99	[1.41-2.81]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
16	11543870	rs12932782	C	T	rs12932782	21703634	9.62E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
16	11544673	rs12932948	G	A	rs12932948	21703634	1.17E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
16	11613169	rs11646835	G	A	rs11646835	21314694	9.55E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	12154378	rs350212	A	G	rs350212	21314694	2.75E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	12201691	rs183008	T	C	rs183008	21529783	2.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
16	12205542	rs350255	A	G	rs350255	21529783	1.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
16	13144688	rs1501304	T	C	rs1501304	20201924	4.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	13490380	rs734826	A	C	rs734826	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	14627694	rs732459	C	T	rs732459	20201924	8.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	14629488	rs12446921	A	G	rs12446921	20201924	8.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	16126475	rs924136	G	A	rs924136	21314694	2.83E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	19156016	rs8062326	G	A	rs8062326	21876473	4.00E-06	BPALC	NA	NA	506 European ancestry cases; 510 European ancestry controls	European(1016)	ALL(1016)	EUR(1016)	ALL(1016)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs8062326-T	Research Support, Non-U.S. Gov't	A	NA
16	20083693	rs1886712	C	G	rs1886712	21314694	5.61E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	22241433	rs4783448	C	T	rs4783448	20201924	7.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	23754198	rs13338358	G	A	rs13338358	21314694	9.65E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	24156946	rs2238493	T	C	rs2238493	21314694	9.29E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	24384711	rs9935277	A	G	rs9935277	24277619	2.38E-04	NA	0.81	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
16	31411185	rs2454908	C	T	rs2454908	22481050	0.0000404	NA	NA	NA	841 cases; 3135 controls	NOPOP(3976)	ALL(3976)	NOPOP(3976)	ALL(3976)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
16	31827215	rs929207	C	T	rs929207	24277619	1.01E-04	NA	1.15	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
16	50089192	rs4785201	A	G	rs4785201	19581569	4.53E-06	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
16	51130159	rs10521221	C	T	rs10521221	24277619	9.51E-04	NA	1.08	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
16	51144335	rs4238821	T	C	rs4238821	24277619	9.51E-04	NA	1.08	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
16	51279824	rs7500931	T	C	rs7500931	21314694	9.89E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	52062912	rs256596	C	A	rs256596	24277619	9.70E-05	NA	0.7	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	LOC388276
16	52083691	rs1592477	C	T	rs1592477	24277619	5.60E-05	NA	0.75	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	LOC388276
16	52089135	rs33364	G	T	rs33364	24277619	2.61E-04	NA	1.2	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	LOC388276
16	52104747	rs42771	G	A	rs42771	24277619	6.27E-04	NA	1.15	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	LOC388276
16	52421140	rs1125832	T	A	rs1125832	21314694	3.38E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	52833422	rs1579237	T	C	rs1579237	20201924	2.16E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	52921779	rs12930501	G	A	rs12930501	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	53004508	rs4784281	A	T	rs4784281	21314694	8.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	53911770	rs1362571	G	T	rs1362571	21314694	7.62E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	54130170	rs16953047	G	T	rs16953047	21314694	4.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	54265765	rs8060235	G	A	rs8060235	21529783	5.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
16	55118798	rs13333707	C	T	rs13333707	20201924	5.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	56612702	rs1909749	C	T	rs1909749	21314694	8.25E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	57113864	rs11639875	C	T	rs11639875	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	57212650	rs767505	A	G	rs767505	22481050	0.00031	NA	NA	NA	841 cases; 3135 controls	NOPOP(3976)	ALL(3976)	NOPOP(3976)	ALL(3976)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
16	58172603	rs1006438	T	C,G	rs1006438	21314694	7.81E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	60395347	rs8050990	C	T	rs8050990	20201924	5.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	60395347	rs8050990	C	T	rs8050990	20201924	5.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	61061390	rs1909766	T	C	rs1909766	20201924	9.90E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	61061390	rs1909766	T	C	rs1909766	pha002892	9.93E-05	phs000125	1.61	[1.27-2.04]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
16	63573514	rs9932227	C	T	rs9932227	20201924	1.30E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	63573514	rs9932227	C	T	rs9932227	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	63573514	rs9932227	C	T	rs9932227	pha002893	1.31E-05	phs000125	1.58	[1.29-1.94]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
16	63588542	rs11865197	T	C	rs11865197	20201924	3.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	63588542	rs11865197	T	C	rs11865197	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	63597260	rs2911181	A	G	rs2911181	20201924	3.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	63597260	rs2911181	A	G	rs2911181	20201924	9.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	66378752	rs11863931	A	G	rs11863931	21314694	4.64E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	66855647	rs363175	C	T	rs363175	21529783	7.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
16	66866633	rs422945	T	G	rs422945	21529783	7.00E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
16	68363181	rs1111571	G	A	rs1111571	21314694	9.50E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	69355506	rs11647864	C	T	rs11647864	21314694	3.92E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	71234989	rs2042423	C	T	rs2042423	21314694	8.84E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	75966770	rs16943694	T	G	rs16943694	20201924	6.83E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	76334673	rs929853	G	A	rs929853	21314694	5.80E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	77233168	rs11640619	G	A	rs11640619	21314694	8.86E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	77377567	rs11643269	G	A	rs11643269	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	77743177	rs10871341	A	G	rs10871341	24277619	8.17E-04	NA	0.41	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
16	78979515	rs9935088	A	G	rs9935088	21314694	7.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	80655883	rs12448290	T	G	rs12448290	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	80656966	rs9927571	G	T	rs9927571	20201924	2.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	81248935	rs8044334	T	G	rs8044334	21529783	8.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
16	81981176	rs4312298	T	G	rs4312298	21956439	7.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	82002104	rs4580155	T	C	rs4580155	21956439	8.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	82301047	rs4782727	A	C	rs4782727	20201924	3.22E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	82721424	rs11640875	A	G	rs11640875	19581569	2.01E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
16	83931538	rs3809622	C	T	rs3809622	20201924	8.51E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	84321653	rs11862438	C	G	rs11862438	21314694	7.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
16	84479620	rs16973814	G	T	rs16973814	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	84489033	rs17815700	T	C	rs17815700	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	84489033	rs17815700	T	C	rs17815700	20201924	7.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	86447184	rs2103284	G	A	rs2103284	20201924	7.35E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	86456633	rs9923190	C	T	rs9923190	20201924	3.62E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
16	88570383	rs868874	T	C	rs868874	23089632	1.28E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	88576794	rs3965782	G	A	rs3965782	24277619	7.40E-04	NA	0.55	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ZFPM1
16	89986760	rs3212369	A	G	rs3212369	20201924	3.78E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	222982	rs9319629	G	A	rs9319629	21314694	8.80E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	1522877	rs4790713	G	A	rs4790713	21314694	7.65E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	1745850	rs4790825	A	G	rs4790825	21314694	9.90E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	2810672	rs17835089	G	C	rs17835089	21314694	4.98E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	4074395	rs1982176	A	C	rs1982176	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4523167	rs11078523	T	C	rs11078523	20201924	4.41E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4594965	rs906453	C	T	rs906453	20201924	2.01E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4594965	rs906453	C	T	rs906453	pha002891	2.01E-05	phs000125	1.92	[1.43-2.63]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	PELP1	intron	NM_014389
17	4604030	rs12451741	G	T	rs12451741	20201924	7.88E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4604634	rs4790687	A	G	rs4790687	20201924	4.31E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4605068	rs4790688	C	T	rs4790688	20201924	4.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4605200	rs4790689	A	C	rs4790689	20201924	4.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4608052	rs7225717	A	G	rs7225717	20201924	4.14E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4608622	rs7215300	T	C	rs7215300	20201924	5.88E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4615098	rs3786047	A	G	rs3786047	20201924	1.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	4622638	rs1045280	C	T	rs1045280	20201924	6.56E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	7665293	rs12453814	A	G	rs12453814	21314694	4.81E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	7922025	rs7503918	C	T	rs7503918	21703634	6.15E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
17	7974834	rs12943817	C	T	rs12943817	20201924	5.43E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	8476743	rs7208821	C	T	rs7208821	21314694	7.41E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	9349826	rs7216753	A	C	rs7216753	21703634	5.46E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
17	9652868	rs424508	T	C	rs424508	21314694	8.77E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	13115254	rs2674959	G	T	rs2674959	20201924	8.16E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	13195189	rs8076501	G	A	rs8076501	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	13195189	rs8076501	G	A	rs8076501	20201924	7.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	14763564	rs9916612	C	T	rs9916612	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	14994001	rs11078278	T	C	rs11078278	20201924	5.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	15066696	rs4792581	T	C	rs4792581	21314694	6.53E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	25636954	rs11080131	T	G	rs11080131	21314694	6.84E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	25850509	rs17778162	G	A	rs17778162	21314694	1.77E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	27431425	rs7212295	A	G	rs7212295	23089632	9.42E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	30085200	rs9910565	A	T	rs9910565	21314694	7.89E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	32860649	rs1860275	G	A	rs1860275	24277619	7.21E-04	NA	0.44	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
17	32869951	rs990510	C	A	rs990510	24277619	2.84E-04	NA	0.42	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
17	32876946	rs758411	A	G	rs758411	24277619	2.42E-04	NA	0.49	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
17	32883256	rs988199	G	A	rs988199	24277619	7.06E-04	NA	0.45	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
17	33032098	rs16970282	A	C	rs16970282	21314694	3.35E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	33457028	rs17629188	G	A	rs17629188	20201924	3.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	33586840	rs899940	T	G	rs899940	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	37444036	rs585961	G	A	rs585961	20201924	3.56E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	37487168	rs7220650	T	C	rs7220650	20201924	5.72E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	37504933	rs8069451	T	C	rs8069451	20201924	8.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	37532916	rs4511574	C	T	rs4511574	20201924	4.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	37574722	rs12452509	G	A	rs12452509	20201924	5.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	37576417	rs7501488	T	G	rs7501488	20201924	5.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	37669704	rs7503705	A	G	rs7503705	20201924	6.71E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	37739274	rs1619021	G	A	rs1619021	20201924	1.69E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	40009955	rs17498875	C	T	rs17498875	21314694	6.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	46756891	rs9909854	C	T	rs9909854	21314694	3.29E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	47449499	rs16948058	C	T	rs16948058	20201924	2.37E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	47449499	rs16948058	C	T	rs16948058	pha002891	2.37E-05	phs000125	2.56	[1.67-4.00]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
17	48019891	rs6504626	T	C	rs6504626	20201924	3.46E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	53468213	rs888206	C	T	rs888206	20201924	3.11E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	53497765	rs4630612	A	G	rs4630612	20201924	4.47E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	53497765	rs4630612	A	G	rs4630612	pha002891	4.47E-05	phs000125	2.13	[1.49-3.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	MMD	intron	NM_012329
17	54976922	rs2525994	C	A	rs2525994	21314694	7.72E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	64284384	rs8081614	T	G	rs8081614	22096494	9.30E-05	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
17	64428682	rs973753	C	T	rs973753	20201924	4.73E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	64428682	rs973753	C	T	rs973753	pha002891	4.73E-05	phs000125	1.96	[1.41-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	PRKCA	intron	NM_002737
17	64432066	rs11079657	A	G	rs11079657	20201924	5.72E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	64816465	rs4791032	A	G	rs4791032	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	64818008	rs11870024	G	A	rs11870024	20201924	4.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	65938655	rs8071463	G	A	rs8071463	21703634	8.93E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
17	65944515	rs11870068	A	C	rs11870068	20202923	7.67E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	65944515	rs11870068	A	C	rs11870068	21703634	8.09E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
17	65944515	rs11870068	A	C	rs11870068	21956439	3.60E-04	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	66389646	rs6501422	T	C	rs6501422	21529783	6.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
17	66825940	rs8071366	G	A	rs8071366	20201924	8.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	68037314	rs180172	A	G	rs180172	21314694	6.48E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	70147581	rs1024826	T	C	rs1024826	20201924	2.65E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	70385567	rs7222185	G	A	rs7222185	21703634	1.64E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
17	71130573	rs4969069	C	T	rs4969069	21314694	8.93E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	71157265	rs1037260	G	T	rs1037260	20201924	6.50E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	71157265	rs1037260	G	T	rs1037260	pha002892	6.50E-05	phs000125	2.26	[1.52-3.37]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
17	72414761	rs9897184	G	A	rs9897184	24277619	1.88E-04	NA	0.55	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
17	72808647	rs16978197	C	T	rs16978197	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	72837012	rs1568447	C	T	rs1568447	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	72837012	rs1568447	C	T	rs1568447	23691058	0.00000408	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	72837832	rs9901283	G	A	rs9901283	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	72837832	rs9901283	G	A	rs9901283	21703634	9.43E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
17	72837832	rs9901283	G	A	rs9901283	23691058	0.00000931	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	72839832	rs11652088	G	A	rs11652088	20201924	4.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	72839832	rs11652088	G	A	rs11652088	21703634	7.08E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
17	72839832	rs11652088	G	A	rs11652088	23691058	0.0000035	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	72850173	rs690533	A	G	rs690533	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	72853450	rs690578	G	A	rs690578	20201924	6.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	72854983	rs2683267	T	C	rs2683267	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	72859078	rs690371	A	G	rs690371	20201924	5.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	72859709	rs690307	C	A	rs690307	20201924	3.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
17	74913937	rs2411042	G	T	rs2411042	21314694	3.42E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	75045983	rs679210	A	C	rs679210	21529783	1.10E-06	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
17	75109300	rs2053568	T	C	rs2053568	21314694	3.17E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	75332456	rs2411109	G	A	rs2411109	21314694	2.69E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	76219591	rs2071214	G	A	rs2071214	21314694	1.77E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
17	81006387	rs1143006	G	A	rs1143006	24277619	6.12E-04	NA	0.41	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	B3GNTL1
18	659236	rs502396	C	T	rs502396	20201924	7.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	1008339	rs789071	G	A	rs789071	24277619	8.58E-04	NA	0.51	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
18	1014560	rs16954588	C	T	rs16954588	24277619	8.58E-04	NA	0.51	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
18	1020820	rs789046	A	G	rs789046	24277619	8.53E-04	NA	0.51	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
18	1344120	rs9950729	T	C	rs9950729	20201924	1.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	1344120	rs9950729	T	C	rs9950729	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	1738361	rs1563188	A	G	rs1563188	20201924	3.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	2533130	rs770224	T	C	rs770224	pha002893	2.12E-05	phs000125	1.52	[1.25-1.85]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
18	2540198	rs2644171	A	G	rs2644171	pha002893	5.02E-05	phs000125	1.49	[1.23-1.79]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	METTL4	intron	NM_022840
18	3316176	rs1791124	T	G	rs1791124	19581569	1.85E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
18	3467413	rs431220	C	T	rs431220	20201924	5.88E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	3467413	rs431220	C	T	rs431220	pha002891	5.88E-05	phs000125	2.33	[1.54-3.45]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	LOC100505592	intron	XR_109463
18	5605989	rs10221410	C	T	rs10221410	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	6467156	rs6506389	C	T	rs6506389	20201924	5.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	6467156	rs6506389	C	T	rs6506389	pha002892	5.62E-05	phs000125	1.64	[1.28-2.04]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
18	6868925	rs2567261	T	C	rs2567261	23089632	1.21E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
18	6928180	rs4797265	G	T	rs4797265	20201924	5.41E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	7249740	rs4797283	C	T	rs4797283	20201924	8.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	9888027	rs11664080	C	T	rs11664080	19581569	6.19E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
18	10140629	rs532241	T	G	rs532241	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	11957685	rs663749	G	C	rs663749	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	11961189	rs619671	C	T	rs619671	20201924	8.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	11972439	rs1787984	A	G	rs1787984	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	13638962	rs4797793	G	A	rs4797793	21314694	5.34E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	21792650	rs17203129	G	A	rs17203129	24277619	5.70E-05	NA	0.84	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	OSBPL1A
18	21806700	rs4281802	T	C	rs4281802	21314694	5.27E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	22157554	rs17203601	G	A	rs17203601	21314694	1.65E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	22791558	rs7226622	C	T	rs7226622	21314694	6.74E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	25826962	rs11564346	C	T	rs11564346	20201924	7.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	32634634	rs7228414	A	G	rs7228414	20201924	6.21E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	35087383	rs10502674	C	T	rs10502674	21314694	6.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	35667915	rs17536346	A	G	rs17536346	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	35678711	rs10502685	C	A	rs10502685	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	38903507	rs4890712	C	A	rs4890712	24277619	4.80E-04	NA	0.42	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
18	38965524	rs7245323	T	C	rs7245323	24277619	8.33E-04	NA	0.4	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
18	43103958	rs8099211	G	A	rs8099211	20201924	8.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	43104212	rs8099273	A	G	rs8099273	20201924	6.66E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	43104212	rs8099273	A	G	rs8099273	pha002891	6.66E-05	phs000125	1.85	[1.37-2.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SLC14A2	intron	NM_001242692
18	43232274	rs7243707	A	C	rs7243707	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	44204713	rs544049	G	A	rs544049	21314694	3.39E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	45688841	rs4939747	C	T	rs4939747	20201924	7.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	45694281	rs6507820	C	T	rs6507820	20201924	5.41E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	45817748	rs9957779	A	G	rs9957779	20201924	1.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	45817748	rs9957779	A	G	rs9957779	20201924	5.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	45977075	rs8082814	G	A	rs8082814	21314694	7.56E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	47037399	rs7238552	C	T	rs7238552	21314694	6.87E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	50130337	rs1221872	A	G	rs1221872	21529783	5.80E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
18	50131110	rs1221874	A	G	rs1221874	21529783	6.40E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
18	50133826	rs1221877	A	G	rs1221877	21529783	5.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
18	50135346	rs1221884	A	G	rs1221884	21529783	7.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
18	50282122	rs10083941	C	T	rs10083941	21529783	1.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
18	50285398	rs768048	C	T	rs768048	21529783	8.00E-06	NA	0.11	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol use disorder factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D019973	Alcohol-Related Disorders	NA	NA	Drug abuse	rs768048-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
18	50288020	rs6508159	C	A	rs6508159	21529783	1.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
18	50308432	rs10515956	G	A	rs10515956	21529783	4.90E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
18	50326885	rs10469016	G	A	rs10469016	21529783	2.70E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
18	56149099	rs7240666	T	C	rs7240666	19581569	6.21E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
18	56578953	rs17761525	C	T	rs17761525	20201924	7.00E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	56578953	rs17761525	C	T	rs17761525	pha002892	7.05E-05	phs000125	3.13	[1.79-5.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	ZNF532	intron	NM_018181
18	56635323	rs7245090	T	G	rs7245090	20201924	1.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	56752500	rs4940444	T	C	rs4940444	21314694	8.92E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	57284133	rs1944980	C	T	rs1944980	20201924	1.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	57284133	rs1944980	C	T	rs1944980	20201924	5.80E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	57284133	rs1944980	C	T	rs1944980	pha002893	5.75E-05	phs000125	1.92	[1.41-2.70]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	CCBE1	intron	NM_133459
18	59207432	rs673401	C	T	rs673401	20201924	3.18E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	60609723	rs7235367	G	A	rs7235367	20201924	8.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	63195218	rs4941342	T	C	rs4941342	20201924	4.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	65318536	rs2448709	G	T	rs2448709	20201924	7.73E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	66095231	rs17212908	C	T	rs17212908	20201924	7.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	67981861	rs7242186	G	A	rs7242186	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	72492689	rs9947276	A	T	rs9947276	24962325	9.00E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs9947276-T	Research Support, N.I.H., Extramural	T	ZNF407
18	72493161	rs7228254	G	C	rs7228254	24962325	9.25E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ZNF407
18	72493314	rs7228438	G	T	rs7228438	24962325	9.25E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ZNF407
18	72494841	rs1974956	G	A	rs1974956	24962325	9.72E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	C	ZNF407
18	72494992	rs7229235	G	A	rs7229235	24962325	9.65E-06	NA	1.39	[1.25-1.53]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ZNF407
18	72504018	rs12956780	G	A	rs12956780	24962325	9.44E-06	NA	1.37	[1.23-1.51]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	G	ZNF407
18	73555117	rs2612391	G	T	rs2612391	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	73758103	rs4891112	G	A	rs4891112	24277619	2.05E-04	NA	0.54	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
18	73763670	rs1030565	A	C	rs1030565	24277619	2.05E-04	NA	0.54	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
18	74491675	rs6565917	A	G	rs6565917	20201924	6.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	74627099	rs562832	C	T	rs562832	21314694	9.40E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	74933003	rs12964446	A	C	rs12964446	24277619	5.24E-04	NA	0.67	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
18	75015563	rs1944550	A	G	rs1944550	21529783	7.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
18	75399395	rs9807163	C	A	rs9807163	20201924	2.06E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	75786773	rs11873161	T	C	rs11873161	20201924	8.68E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	76178452	rs12326991	T	C	rs12326991	20201924	7.62E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	76336288	rs10401125	C	T	rs10401125	20201924	3.67E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	76337612	rs9960787	G	A	rs9960787	20201924	1.91E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
18	76503253	rs9945493	G	A	rs9945493	21956439	5.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	77716624	rs12953577	G	A	rs12953577	21314694	9.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
18	77908065	rs12953980	A	G	rs12953980	24277619	6.07E-04	NA	1.37	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	LOC100130522
19	960445	rs1637995	A	G	rs1637995	21956439	9.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	988136	rs7249037	G	A	rs7249037	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	1002847	rs4807395	A	G	rs4807395	20201924	2.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	1002847	rs4807395	A	G	rs4807395	20201924	7.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	1526470	rs2292453	G	A	rs2292453	24277619	7.23E-04	NA	0.41	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	PLK5
19	1580334	rs7252741	T	C	rs7252741	24277619	5.52E-04	NA	0.41	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	MBD3
19	1858873	rs4807154	C	T	rs4807154	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	2106696	rs10413398	T	C	rs10413398	21314694	2.47E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	3974965	rs745414	G	A	rs745414	21314694	9.65E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	4487806	rs16992410	A	G	rs16992410	20201924	6.06E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	5258490	rs4807016	G	A	rs4807016	20201924	1.20E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	5258490	rs4807016	G	A	rs4807016	20201924	8.30E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	5258490	rs4807016	G	A	rs4807016	pha002892	8.29E-05	phs000125	1.43	[1.19-1.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	PTPRS	intron	NM_002850
19	6815948	rs4807101	C	T	rs4807101	23089632	1.06E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	6909565	rs673320	C	A	rs673320	21314694	4.75E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	7114213	rs1864193	C	A	rs1864193	21314694	2.27E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	7182963	rs10500204	A	C	rs10500204	20201924	5.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	7516243	rs12610760	A	G	rs12610760	20201924	8.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	7529415	rs2287919	C	T	rs2287919	20201924	7.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	7833690	rs3745376	G	T	rs3745376	21314694	5.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	8172681	rs10411526	A	G	rs10411526	24277619	7.55E-04	NA	1.45	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	FBN3
19	8973217	rs10412487	T	C	rs10412487	19581569	5.81E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
19	12434902	rs7246738	T	C	rs7246738	20201924	5.48E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	12436410	rs12610507	A	C	rs12610507	20201924	8.69E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	12439868	rs1593000	C	T	rs1593000	20201924	2.31E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	12441244	rs9676962	C	T	rs9676962	20201924	5.84E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	13942587	rs12610873	G	A	rs12610873	20201924	1.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	16072037	rs7251890	A	C	rs7251890	24277619	6.26E-04	NA	0.77	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
19	17099980	rs2353203	G	A	rs2353203	20201924	3.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	17232499	rs11667918	C	T	rs11667918	21314694	8.77E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	21857227	rs12232841	T	G	rs12232841	21703634	5.93E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
19	22837108	rs7250285	C	T	rs7250285	24277619	6.09E-04	NA	0.57	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	ZNF492
19	22925965	rs12974988	G	T	rs12974988	24277619	5.65E-04	NA	0.58	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
19	22956900	rs6511383	C	T	rs6511383	24277619	7.02E-04	NA	0.56	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T,C	ZNF99
19	29928853	rs10423905	A	C	rs10423905	20201924	5.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	29928853	rs10423905	A	C	rs10423905	20201924	6.60E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	30172341	rs8102949	T	C	rs8102949	21314694	5.63E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	30312582	rs3218065	G	A	rs3218065	20201924	2.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	32471523	rs17703610	A	C	rs17703610	21956439	5.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	35807845	rs11666282	C	T	rs11666282	20201924	7.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	36068062	rs12972040	G	C	rs12972040	21314694	4.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	39789115	rs30461	A	G	rs30461	21529783	3.30E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
19	39826479	rs3786949	G	A	rs3786949	21529783	2.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
19	39844176	rs30454	G	A	rs30454	21529783	7.10E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
19	40256328	rs1972537	G	A	rs1972537	21314694	9.55E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	40328615	rs616650	C	T	rs616650	21314694	3.89E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	40816530	rs7247916	A	G	rs7247916	21529783	6.20E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
19	41525952	rs1552223	G	A	rs1552223	21314694	3.13E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	42106367	rs16975393	C	A	rs16975393	21314694	2.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	42275099	rs2701	A	G	rs2701	21314694	1.05E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	42306043	rs7251960	T	C	rs7251960	21314694	2.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	44888276	rs4142248	T	C	rs4142248	20201924	4.77E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	45808142	rs344797	T	G	rs344797	21314694	9.22E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	46034558	rs8111589	C	T	rs8111589	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	46034558	rs8111589	C	T	rs8111589	23691058	0.00000827	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
19	46063167	rs1264226	G	A	rs1264226	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	46066318	rs16979890	G	A	rs16979890	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	47221758	rs10412340	G	A	rs10412340	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	47224590	rs3786704	C	T	rs3786704	20201924	7.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	47947982	rs830140	A	G	rs830140	24277619	5.63E-04	NA	0.47	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	SLC8A2
19	48836082	rs3745720	A	C	rs3745720	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	48935653	rs34997741	T	C	rs34997741	21314694	4.46E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	49738482	rs1177825	C	T	rs1177825	20201924	4.85E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	50316754	rs2286948	C	T	rs2286948	21314694	6.88E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	50563220	rs10422999	C	A	rs10422999	21314694	9.82E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	52187568	rs11670215	T	G	rs11670215	20201924	5.61E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	52899556	rs324119	C	A,G,T	rs324119	21314694	8.43E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	53633550	rs10423632	A	G	rs10423632	21314694	6.08E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	55074470	rs10402506	A	G	rs10402506	21314694	9.89E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	55105409	rs12980993	A	C	rs12980993	21314694	7.05E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	55377211	rs3826878	A	G	rs3826878	24277619	2.00E-05	NA	1	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	KIR3DL2
19	55632393	rs10417874	G	A	rs10417874	21314694	2.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	55842045	rs11084394	T	C	rs11084394	20201924	4.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	55842045	rs11084394	T	C	rs11084394	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	56293701	rs1423071	G	A	rs1423071	20201924	4.65E-06	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	56293701	rs1423071	G	A	rs1423071	pha002891	4.65E-06	phs000125	2.17	[1.56-3.03]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
19	57535252	rs8108432	A	G	rs8108432	20201924	4.92E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
19	57781095	rs2097983	A	C	rs2097983	21314694	8.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
19	57804362	rs3746228	G	A	rs3746228	21314694	9.74E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	689537	rs6117232	C	T	rs6117232	21529783	9.50E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
20	747835	rs6054627	A	G	rs6054627	21314694	6.37E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	3019957	rs8125955	A	C	rs8125955	20201924	7.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	4100321	rs6037767	T	C	rs6037767	20201924	2.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	4240417	rs4813680	C	A	rs4813680	20201924	8.30E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	4240417	rs4813680	C	A	rs4813680	pha002893	8.33E-05	phs000125	1.82	[1.35-2.44]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NA	NA	NA
20	4240509	rs8115863	T	C	rs8115863	20201924	8.30E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	4240509	rs8115863	T	C	rs8115863	pha002893	8.33E-05	phs000125	1.82	[1.35-2.44]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NA	NA	NA
20	4378871	rs6139415	A	G	rs6139415	21703634	2.94E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	4679519	rs11087653	G	A	rs11087653	21314694	7.70E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	4742080	rs968433	C	G	rs968433	21314694	1.65E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	6468261	rs10485705	G	T	rs10485705	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	6468371	rs1970008	A	G	rs1970008	20201924	8.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	6470805	rs6117294	T	G	rs6117294	20201924	3.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	6470805	rs6117294	T	G	rs6117294	20201924	4.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	6771370	rs6054517	C	A	rs6054517	20201924	7.22E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	8006196	rs6039005	G	T	rs6039005	20201924	7.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	8949064	rs2206266	T	C	rs2206266	21314694	7.10E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	10154444	rs6077681	T	C	rs6077681	24277619	9.04E-04	NA	1.1	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	LOC100131208
20	10643850	rs7267595	A	C	rs7267595	21314694	8.65E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	10843840	rs2024683	A	G	rs2024683	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	12898621	rs9680021	A	C	rs9680021	24277619	9.84E-04	NA	0.5	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NA
20	12988524	rs360534	G	A	rs360534	21703634	3.22E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	14517220	rs6079482	T	C	rs6079482	20201924	4.20E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	14517220	rs6079482	T	C	rs6079482	20201924	5.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	14517220	rs6079482	T	C	rs6079482	pha002892	4.19E-05	phs000125	1.64	[1.30-2.08]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	MACROD2	intron	NM_080676
20	14548676	rs6110333	C	T	rs6110333	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	16106040	rs6080131	A	G	rs6080131	20201924	8.16E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	17207721	rs3818916	G	T	rs3818916	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	17207721	rs3818916	G	T	rs3818916	20201924	4.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	17228744	rs1578405	A	G	rs1578405	24277619	3.73E-04	NA	0.59	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	PCSK2
20	17726683	rs6044991	A	G	rs6044991	21529783	9.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
20	18070328	rs4813301	G	A	rs4813301	21314694	1.47E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	21095936	rs6047255	A	G	rs6047255	21703634	7.96E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	21100138	rs6082329	A	C	rs6082329	21703634	7.95E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	23097880	rs1320561	G	A	rs1320561	21314694	8.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	23725019	rs4134385	A	G	rs4134385	23089632	4.93E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	24589790	rs6049811	T	G	rs6049811	21314694	9.71E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	31511702	rs11697967	A	C	rs11697967	21314694	6.80E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	31598781	rs6120085	T	C	rs6120085	21314694	8.79E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	32467139	rs6120401	C	T	rs6120401	21314694	6.18E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	33132191	rs6088519	C	T	rs6088519	23089632	3.00E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	33319388	rs6141509	G	A	rs6141509	23089632	8.80E-07	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	33357715	rs6060038	G	A	rs6060038	23089632	6.88E-07	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	33536897	rs6060124	C	A	rs6060124	23089632	0.000203	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	33536897	rs6060124	C	A	rs6060124	23089632	4.41E-07	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	33551100	rs6088664	G	A	rs6088664	23089632	3.23E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	33553677	rs6579204	A	G	rs6579204	23089632	0.00000454	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	33604042	rs3736802	T	C	rs3736802	23089632	7.56E-07	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	33734493	rs1415771	G	A	rs1415771	23089632	5.03E-06	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	40341122	rs16986005	G	A	rs16986005	21314694	1.06E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	42525490	rs11696193	A	G	rs11696193	20201924	4.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	42525490	rs11696193	A	G	rs11696193	20201924	6.20E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	42525490	rs11696193	A	G	rs11696193	pha002892	6.20E-05	phs000125	1.45	[1.22-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NA	NA	NA
20	42775843	rs2017246	A	G	rs2017246	20201924	6.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	44378211	rs462145	A	G	rs462145	21314694	8.96E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	44545048	rs4810479	C	T	rs4810479	20201924	3.33E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	44712175	rs6074015	C	T	rs6074015	20201924	2.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	44712175	rs6074015	C	T	rs6074015	20201924	4.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	45539797	rs6066110	A	G	rs6066110	21314694	6.73E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	45557451	rs6018185	T	C	rs6018185	20201924	4.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	45557451	rs6018185	T	C	rs6018185	20201924	9.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	46059823	rs6018477	A	C	rs6018477	20201924	4.49E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	48434636	rs8118160	A	G	rs8118160	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	48454671	rs4809760	A	G	rs4809760	20201924	2.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	48466885	rs17786105	A	G	rs17786105	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	48466885	rs17786105	A	G	rs17786105	20201924	6.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	48484241	rs2281223	G	A	rs2281223	20201924	2.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	48918420	rs7269352	A	G	rs7269352	20201924	3.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	48918420	rs7269352	A	G	rs7269352	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	51897115	rs1543080	C	A	rs1543080	21314694	5.59E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	51917248	rs6022378	A	G	rs6022378	20201924	5.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	51922638	rs1996017	T	C	rs1996017	20201924	4.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	52278258	rs6091723	G	A	rs6091723	21314694	1.63E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	54541019	rs1370271	T	C	rs1370271	21314694	6.58E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	54746137	rs6014619	C	G	rs6014619	21314694	5.33E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
20	56719673	rs6128273	C	A	rs6128273	20201924	8.02E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	59390992	rs10153975	T	C	rs10153975	20201924	8.33E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	60749183	rs6142969	C	T	rs6142969	20201924	2.78E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	60750857	rs6142970	C	T	rs6142970	20201924	1.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
20	61044227	rs6061245	T	C	rs6061245	21314694	9.00E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
21	15671024	rs2822557	G	A	rs2822557	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	15685452	rs887772	T	G	rs887772	20201924	7.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	15687493	rs8131875	A	G	rs8131875	20201924	7.80E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	15687493	rs8131875	A	G	rs8131875	pha002892	7.83E-05	phs000125	1.47	[1.20-1.75]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
21	15709614	rs2822582	T	G	rs2822582	20201924	6.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	15710017	rs2822586	T	C	rs2822586	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	15710017	rs2822586	T	C	rs2822586	20201924	7.00E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	15711540	rs2822589	T	C	rs2822589	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	15940389	rs760347	C	T	rs760347	21314694	6.85E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
21	20050573	rs9975541	G	A	rs9975541	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	20050573	rs9975541	G	A	rs9975541	20201924	8.70E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	20050573	rs9975541	G	A	rs9975541	pha002893	8.70E-05	phs000125	3.13	[1.75-5.56]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NA	NA	NA
21	20827199	rs1387616	A	G	rs1387616	21529783	5.60E-05	NA	NA	NA	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
21	22487854	rs2826659	A	C	rs2826659	24962325	7.00E-06	NA	1.35	[1.21-1.49]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs2826659-A	Research Support, N.I.H., Extramural	A	NCAM2
21	22488414	rs2826660	A	G	rs2826660	24962325	6.52E-06	NA	1.35	[1.21-1.49]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	Research Support, N.I.H., Extramural	A	NCAM2
21	22636834	rs4605456	C	T	rs4605456	pha002893	8.79E-05	phs000125	1.67	[1.30-2.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	T	NCAM2	intron	NM_004540
21	22643720	rs8127865	A	G	rs8127865	20201924	5.20E-05	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	22643720	rs8127865	A	G	rs8127865	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	22643720	rs8127865	A	G	rs8127865	pha002893	5.20E-05	phs000125	1.69	[1.32-2.17]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NCAM2	intron	NM_004540
21	22677774	rs2218433	A	G	rs2218433	pha002893	6.96E-05	phs000125	1.67	[1.30-2.17]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	NCAM2	intron	NM_004540
21	22679636	rs7279496	C	A	rs7279496	pha002893	8.95E-05	phs000125	1.67	[1.28-2.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	A	NCAM2	intron	NM_004540
21	22687580	rs8126935	A	G	rs8126935	pha002893	7.53E-05	phs000125	1.67	[1.30-2.13]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	NCAM2	intron	NM_004540
21	23358432	rs2827182	C	T	rs2827182	20201924	3.10E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	23358432	rs2827182	C	T	rs2827182	20201924	3.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	23631676	rs2827312	G	T	rs2827312	21529783	8.00E-06	NA	0.09	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (heaviness of drinking)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs2827312-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
21	23975806	rs2827634	G	A	rs2827634	24277619	5.93E-04	NA	0.55	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
21	25563034	rs17398828	T	G	rs17398828	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	26215045	rs11700693	C	T	rs11700693	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	26215045	rs532723366	CTCTG	C	rs11700693	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	26222398	rs6516643	T	C	rs6516643	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	26340199	rs17000583	A	G	rs17000583	20201924	2.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	26463074	rs2829538	T	C	rs2829538	20201924	2.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	26463074	rs2829538	T	C	rs2829538	20201924	4.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	27361704	rs7276036	G	A	rs7276036	20201924	2.76E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	27458409	rs2830045	A	G	rs2830045	23691058	0.00000631	NA	NA	NA	847 European ancestry cases; 552 European ancestry controls	European(1399)	ALL(1399)	EUR(1399)	ALL(1399)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
21	28596893	rs235938	T	C	rs235938	24277619	5.16E-04	NA	0.52	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
21	33021417	rs8128956	T	A	rs8128956	21314694	7.34E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
21	33022020	rs2173962	T	C	rs2173962	21314694	7.16E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
21	33087863	rs2833487	A	G	rs2833487	21314694	6.04E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
21	37651313	rs2284642	G	T	rs2284642	20201924	6.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	37651313	rs2284642	G	T	rs2284642	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	38082812	rs9977521	C	T	rs9977521	24277619	9.78E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	SIM2
21	38791156	rs2835725	A	G	rs2835725	20201924	8.05E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	39767874	rs2836364	C	T	rs2836364	19581569	3.36E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
21	40347685	rs2836800	C	T	rs2836800	21314694	3.65E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
21	40400958	rs2242930	G	A	rs2242930	20201924	1.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	41287057	rs7276341	A	G	rs7276341	21314694	6.98E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
21	41303895	rs2837302	C	T	rs2837302	20201924	3.20E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	41491366	rs16999304	T	C	rs16999304	20201924	1.97E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	41498026	rs2837437	T	C	rs2837437	20201924	8.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	42156432	rs8128946	A	G	rs8128946	20201924	6.30E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	42156432	rs8128946	A	G	rs8128946	20201924	6.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	42790341	rs758342	T	C	rs758342	24277619	2.74E-04	NA	0.66	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	NA
21	43407668	rs11702690	A	G	rs11702690	19581569	4.79E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
21	43706776	rs3788007	G	A	rs3788007	20201924	1.19E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	44871063	rs9680399	G	A	rs9680399	20201924	6.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
21	45595060	rs7280236	C	T	rs7280236	21703634	1.66E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
21	47445791	rs4293630	A	G	rs4293630	21529783	7.00E-06	NA	0.11	[NA] unit increase	8,754 European ancestry family members	European(8754)	ALL(8754)	EUR(8754)	ALL(8754)	Alcoholism (alcohol dependence factor score)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	NA	NA	Drug abuse	rs4293630-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
22	17057138	rs5746647	G	T	rs5746647	20201924	8.64E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	24148273	rs2267032	A	G	rs2267032	20201924	5.80E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	24148273	rs2267032	A	G	rs2267032	20201924	8.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	26713964	rs6519647	G	T	rs6519647	23089632	1.33E-05	NA	NA	NA	2010 individuals	NOPOP(2010)	ALL(2010)	NOPOP(2010)	ALL(2010)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
22	26774580	rs667577	A	G	rs667577	20201924	1.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	26774580	rs667577	A	G	rs667577	20201924	8.60E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	26774580	rs667577	A	G	rs667577	pha002892	8.58E-05	phs000125	1.45	[1.20-1.72]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SEZ6L	intron	NM_021115
22	26878024	rs5761557	A	G	rs5761557	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	26916722	rs134157	C	T	rs134157	24277619	2.46E-04	NA	0.41	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	T	NA
22	26924312	rs2283822	C	T	rs2283822	24277619	9.38E-04	NA	0.48	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	C	TPST2
22	26924535	rs2283825	C	T	rs2283825	21314694	8.43E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	26969061	rs2283839	A	C	rs2283839	21314694	7.66E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	26981039	rs4822743	A	G	rs4822743	24277619	3.20E-05	NA	0.53	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	TPST2
22	27021401	rs2071862	G	A	rs2071862	24277619	6.86E-04	NA	0.43	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	CRYBA4
22	27186321	rs4822791	G	A	rs4822791	21956439	5.00E-06	NA	NA	NA	1,409 European ancestry cases; 1,518 European ancestry controls; 681 African American cases; 508 African American controls	African American(1189)	European(2927)	ALL(4116)	AFR(1189)	EUR(2927)	ALL(4116)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	34078057	rs5754638	A	T	rs5754638	24962325	8.00E-06	NA	1.44	[1.28-1.60]	685 European ancestry cases; 1,103 European ancestry controls from 118 families	European(1788)	ALL(1788)	EUR(1788)	ALL(1788)	Alcohol dependence (age at onset)	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	rs5754638-T	Research Support, N.I.H., Extramural	A	LARGE
22	34291750	rs2213360	A	G	rs2213360	20201924	1.27E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	35503072	rs9622147	C	T	rs9622147	21314694	5.45E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	36120510	rs5999984	G	C	rs5999984	21314694	4.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	37970866	rs4821670	T	C	rs4821670	21703634	7.42E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
22	39592181	rs5750769	C	T	rs5750769	21314694	3.82E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	39764824	rs5757642	T	C	rs5757642	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	39769818	rs1569499	T	C	rs1569499	20201924	5.54E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	39769818	rs1569499	T	C	rs1569499	pha002891	5.54E-05	phs000125	1.89	[1.39-2.58]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	C	SYNGR1	intron	NM_004711
22	39770597	rs4821888	A	G	rs4821888	20201924	1.14E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	39770597	rs4821888	A	G	rs4821888	pha002891	1.14E-05	phs000125	2.04	[1.48-2.81]	NA	ALL(0)	ALL(0)	Alcoholism	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	NA	NA	NA	NA	Drug abuse	NA	NA	G	SYNGR1	intron	NM_004711
22	43079754	rs17003212	T	C	rs17003212	20201924	3.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	43079754	rs17003212	T	C	rs17003212	20201924	7.50E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	43084613	rs736013	T	C	rs736013	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	43084613	rs736013	T	C	rs736013	20201924	3.40E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	43088463	rs3747193	G	T	rs3747193	20201924	1.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	43153146	rs7287569	C	A	rs7287569	24277619	7.68E-04	NA	0.61	[NA] unit increase	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	A,C	NA
22	43498161	rs135015	T	C	rs135015	21314694	7.02E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	44757071	rs2014530	C	T	rs2014530	19581569	3.92E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
22	45811362	rs9614466	A	G	rs9614466	20201924	1.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	45838817	rs9614670	C	T	rs9614670	20201924	6.84E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	46213591	rs7284693	A	G	rs7284693	21314694	2.52E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	46984306	rs875778	T	C	rs875778	24277619	9.70E-04	NA	0.68	[NA] unit decrease	102 Han Chinese ancestry cases; 212 Han Chinese ancestry controls	Han Chinese(314)	ALL(314)	ASN(314)	ALL(314)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	G	NA
22	47659014	rs11704468	C	T	rs11704468	20201924	6.80E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	48453666	rs1014674	C	A	rs1014674	21703634	3.02E-05	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
22	48457696	rs737791	G	A	rs737791	21703634	8.12E-06	NA	NA	NA	1,283 European ancestry cases; 1,416 European ancestry controls	European(2699)	ALL(2699)	EUR(2699)	ALL(2699)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
22	49177741	rs6010529	A	G	rs6010529	21314694	8.68E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
22	50456791	rs137878	G	A	rs137878	20201924	4.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
22	50456791	rs137878	G	A	rs137878	20201924	6.90E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	5094340	rs17219798	G	A	rs17219798	20201924	7.30E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	10231691	rs12388359	G	T	rs12388359	19581569	4.00E-06	NA	1.61	[1.32-2.00]	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	rs12388359-T	Multicenter Study	Research Support, Non-U.S. Gov't	G
X	10305329	rs2214261	G	A	rs2214261	19581569	9.83E-05	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
X	11717299	rs999700	T	C	rs999700	20201924	5.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	14979765	rs5980083	T	C	rs5980083	20201924	8.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	17080716	rs7058279	T	C	rs7058279	20201924	3.74E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	24163287	rs5949232	G	A	rs5949232	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	31437805	rs1921968	C	T	rs1921968	21314694	3.46E-04	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
X	32115141	rs2405543	G	A	rs2405543	20201924	8.40E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	34137327	rs3006120	G	A	rs3006120	20201924	6.25E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	34180828	rs5928439	A	G	rs5928439	20201924	7.58E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	35184535	rs4610908	G	A	rs4610908	20201924	5.81E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	35184535	rs4610908	G	A	rs4610908	20202923	5.49E-06	NA	NA	NA	1,235 European American cases; 662 African American cases; 1,433 European American controls; 499 African American controls	African American(1161)	European American(2668)	ALL(3829)	AFR(1161)	EUR(2668)	ALL(3829)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
X	35184535	rs4610908	G	A	rs4610908	22096494	5.70E-07	Alcohol dependence	NA	NA	681 African ancestry cases; 508 African ancestry controls	African(1189)	ALL(1189)	AFR(1189)	ALL(1189)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, U.S. Gov't, Non-P.H.S.
X	36976855	rs28680858	T	C	rs28680858	20201924	6.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	37034677	rs28797478	G	A	rs28797478	20201924	4.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	42648004	rs5964215	T	C	rs5964215	20201924	6.28E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	42649528	rs5964217	G	A	rs5964217	20201924	3.44E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	42662929	rs5991588	C	T	rs5991588	20201924	5.81E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	55960724	rs6417935	T	C	rs6417935	20201924	8.79E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	68411445	rs943166	C	T	rs943166	20201924	7.07E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	69485529	rs3843841	A	C	rs3843841	20201924	4.01E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	82871195	rs5922838	A	G	rs5922838	20201924	7.00E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	82954490	rs5968205	C	T	rs5968205	20201924	6.70E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	82971008	rs5922858	G	T	rs5922858	20201924	7.10E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	92653385	rs7060195	T	G	rs7060195	20201924	8.42E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	97534844	rs1414298	T	C	rs1414298	20201924	8.23E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	99479968	rs5921523	A	C	rs5921523	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	105278765	rs17332369	T	A	rs17332369	21314694	8.82E-05	NA	NA	NA	2,357 European ancestry individuals; 812 African American individuals	African American(812)	European(2357)	ALL(3169)	AFR(812)	EUR(2357)	ALL(3169)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Research Support, N.I.H., Extramural
X	109471360	rs17254838	T	G	rs17254838	20201924	3.20E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	109549026	rs5942915	G	A	rs5942915	20201924	7.31E-05	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	116487848	rs12858772	C	T	rs12858772	19581569	2.57E-06	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
X	118189421	rs17261061	C	A	rs17261061	20201924	4.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	119393600	rs12857770	C	T	rs12857770	20201924	4.66E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	122141925	rs3013029	A	G	rs3013029	20201924	7.41E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	128735199	rs16999497	T	C	rs16999497	20201924	6.36E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	135732148	rs5930973	G	A	rs5930973	20201924	1.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	135732148	rs5930973	G	A	rs5930973	20201924	3.70E-04	Alcohol dependence (early age of onset)	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	136373714	rs5931118	G	A	rs5931118	20201924	8.60E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	148622730	rs3747443	G	A,C,T	rs3747443	20201924	7.90E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	149233232	rs6608304	G	A	rs6608304	20201924	2.04E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	151300722	rs1844895	C	T	rs1844895	20201924	8.50E-04	Alcohol dependence	NA	NA	847 European ancestry cases; 552 European ancestry controls; 345 African American cases; 140 African American controls	African American(485)	European(1399)	ALL(1884)	AFR(485)	EUR(1399)	ALL(1884)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study
X	153724351	rs12392447	G	A	rs12392447	19581569	2.88E-08	NA	NA	NA	476 European ancestry cases; 1,358 European ancestry controls	European(1834)	ALL(1834)	EUR(1834)	ALL(1834)	Alcohol dependence	HPOID:0000707	Abnormality of the nervous system	DOID:0050741	alcohol dependence	D000437	Alcoholism	EFOID:0003829	alcohol dependence	Drug abuse	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:9)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0001973	aripiprazole	D000068180	-	alcoholism	MESH:D000437	therapeutic	15960570
C0001973	ivermectin	D007559	70288-86-7	alcoholism	MESH:D000437	therapeutic	21402096
C0001973	lorazepam	D008140	846-49-1	alcoholism	MESH:D000437	therapeutic	12920420
C0001973	nicotine	D009538	-	alcoholism	MESH:D000437	marker/mechanism	17067804
C0001973	olanzapine	C076029	132539-06-1	alcoholism	MESH:D000437	therapeutic	12920420
C0001973	pregabalin	D000069583	-	alcoholism	MESH:D000437	therapeutic	23782139
C0001973	pyridoxine	D011736	-	alcoholism	MESH:D000437	therapeutic	619758
C0001973	topiramate	C052342	97240-79-4	alcoholism	MESH:D000437	therapeutic	16432681
C0001973	valproic acid	D014635	99-66-1	alcoholism	MESH:D000437	therapeutic	15643110

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)