PedAM
Pediatric Disease Annotations & Medicines
| adenosquamous carcinoma | ||||
| Disease ID | 1253 |
|---|---|
| Disease | adenosquamous carcinoma |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0030731 | Carcinoma | 2 HP:0002669 | Osteosarcoma | 2 HP:0002860 | Squamous cell carcinoma | 1 HP:0002835 | Aspiration | 1 HP:0002584 | Intestinal hemorrhage | 1 HP:0030078 | Lung adenocarcinoma | 1 HP:0002664 | Neoplasia | 1 HP:0002239 | Gastrointestinal hemorrhage | 1 HP:0040276 | Adenocarcinoma of the colon | 1 |
| Disease ID | 1253 |
|---|---|
| Disease | adenosquamous carcinoma |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:3) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:3) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs121434569 | 21635547 | 1956 | EGFR | umls:C0206623 | BeFree | We analyzed 147 NSCLC tissues [70 adenocarcinomas (AD), 62 squamous cell carcinomas (SQ), 12 large cell carcinomas (LC), and three adenosquamous carcinomas] that had not been exposed to the TKI therapies, and found 12 (8.2%; 12/147) EGFR T790M mutation in eight AD (11.4%), three SQ (4.8%), and one LC (8.3%) by the PNA-clamping PCR. | 0.009248887 | 2011 | EGFR;EGFR-AS1 | 7 | 55181378 | C | T |
| rs25487 | 15990162 | 7515 | XRCC1 | umls:C0206623 | BeFree | This is the first report that the XRCC1 Arg399Gln polymorphism might be important in relation to the risk of adenocarcinoma/adenosquamous carcinoma of the cervix. | 0.000271442 | 2005 | XRCC1 | 19 | 43551574 | T | C |
| rs386493716 | 15990162 | 7515 | XRCC1 | umls:C0206623 | BeFree | This is the first report that the XRCC1 Arg399Gln polymorphism might be important in relation to the risk of adenocarcinoma/adenosquamous carcinoma of the cervix. | 0.000271442 | 2005 | NA | NA | NA | NA | NA |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
Chemical(Total Drugs:1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0206623 | diethylstilbestrol | D004054 | 56-53-1 | carcinoma, adenosquamous | MESH:D018196 | marker/mechanism | 5076457 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |