PedAM
Pediatric Disease Annotations & Medicines
| acute stress disorder | ||||
| Disease ID | 1502 |
|---|---|
| Disease | acute stress disorder |
| Definition | An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by dissociative symptoms; vivid recollections of the traumatic event; avoidance of stimuli associated with the traumatic event; and a constant state of hyperarousal for no more than one month. |
| Synonym | (examination fear) or (flying phobia) or (stage fright) or (acute stress reaction nos) (examination fear) or (flying phobia) or (stage fright) or (acute stress reaction nos) (disorder) [x]acute crisis reaction [x]acute reaction to stress [x]acute stress reaction [x]psychic shock acute crisis reaction acute disorders stress acute reaction to stress acute stress dis acute stress disorder (disorder) acute stress disorders acute stress react nos acute stress reaction acute stress reaction nos acute stress reaction nos (disorder) acute traumatic stress disorder gross stress reaction gross stress reaction (acute) gross stress reaction (disorder) gross stress reaction, nos post-traumatic stress - acute psychic shock psychic shock (disorder) stress dis acute stress dis traumatic acute stress disorder, acute stress disorders, acute stress disorders, traumatic, acute stress disorders, traumatic, acute [disease/finding] unspecified acute reaction to stress |
| DOID | |
| ICD10 | |
| UMLS | C0236816 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:7) C0011570 | depression | 1 C0152101 | hypoplastic left heart | 1 C0027051 | myocardial infarct | 1 C0152101 | hypoplastic left heart syndrome | 1 C0027051 | myocardial infarction | 1 C0003467 | anxiety | 1 C0155626 | acute myocardial infarction | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:40) 9817 | KEAP1 | DISEASES 2908 | NR3C1 | DISEASES 6532 | SLC6A4 | DISEASES 5465 | PPARA | DISEASES 2033 | EP300 | DISEASES 9759 | HDAC4 | DISEASES 7535 | ZAP70 | DISEASES 6647 | SOD1 | DISEASES 150094 | SIK1 | DISEASES 10428 | CFDP1 | DISEASES 3362 | HTR6 | DISEASES 6632 | SNRPD1 | DISEASES 4909 | NTF4 | DISEASES 116071 | BATF2 | DISEASES 43 | ACHE | DISEASES 7351 | UCP2 | DISEASES 3355 | HTR1F | DISEASES 7352 | UCP3 | DISEASES 8408 | ULK1 | DISEASES 2289 | FKBP5 | DISEASES 29102 | DROSHA | DISEASES 3767 | KCNJ11 | DISEASES 2555 | GABRA2 | DISEASES 51643 | TMBIM4 | DISEASES 10758 | TRAF3IP2 | DISEASES 19 | ABCA1 | DISEASES 7046 | TGFBR1 | DISEASES 6850 | SYK | DISEASES 7133 | TNFRSF1B | DISEASES 22894 | DIS3 | DISEASES 388585 | HES5 | DISEASES 444 | ASPH | DISEASES 100134934 | TEN1 | DISEASES 501 | ALDH7A1 | DISEASES 4908 | NTF3 | DISEASES 54475 | NLE1 | DISEASES 627 | BDNF | DISEASES 4914 | NTRK1 | DISEASES 104355217 | ERICD | DISEASES 79104 | MEG8 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1502 |
|---|---|
| Disease | acute stress disorder |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:6) HP:0004383 | Underdeveloped left heart | 1 HP:0000716 | Depression | 1 HP:0000739 | Anxiety | 1 HP:0001658 | Myocardial infarction | 1 HP:0012531 | Pain | 1 HP:0002354 | Memory loss | 1 |
| Disease ID | 1502 |
|---|---|
| Disease | acute stress disorder |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs25531 | 21893641 | 6532 | SLC6A4 | umls:C0236816 | BeFree | We found that although the STin2 variant and 5-HTTLPR alone did not associate with increased PTSD symptoms, rs25531 and the 5-HTTLPR multimarker genotype (combined 5-HTTLPR and rs25531) were associated with significantly increased acute stress disorder symptoms at 2 to 4 weeks postshooting (n = 161; P < .05). | 0.000271442 | 2012 | SLC6A4;LOC105371720 | 17 | 30237328 | T | C |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |