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Pediatric Disease Annotations & Medicines



   acute pyelonephritis
  

Disease ID 1763
Disease acute pyelonephritis
Definition
Sudden onset pyelonephritis.
Synonym
acute kidney infection
acute pn - pyelonephritis
acute pyelonephritis (disorder)
acute pyelonephritis nos
acute pyelonephritis nos (disorder)
apn - acute pyelonephritis
pyelonephritis acute
pyelonephritis, acute
DOID
UMLS
C0520575
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:23)
C0178879  |  obstructive uropathy  |  2
C0011849  |  diabetes mellitus  |  2
C0042075  |  uropathy  |  2
C0042580  |  vesicoureteral reflux  |  2
C0011847  |  diabetes  |  2
C0007115  |  thyroid ca  |  1
C0549473  |  thyroid carcinoma  |  1
C0027709  |  nephrocalcinosis  |  1
C0022658  |  kidney disease  |  1
C0029927  |  ovarian cyst  |  1
C0035078  |  renal failure  |  1
C0004623  |  bacterial infection  |  1
C0011860  |  type 2 diabetes  |  1
C0020295  |  hydronephrosis  |  1
C0025229  |  melioidosis  |  1
C0238461  |  anaplastic thyroid carcinoma  |  1
C0011860  |  type 2 diabetes mellitus  |  1
C0002871  |  anemia  |  1
C0022660  |  acute renal failure  |  1
C0004659  |  bacteriuria  |  1
C0002871  |  anaemia  |  1
C0022667  |  papillary necrosis  |  1
C0272412  |  splenic abscess  |  1
Curated Gene(Waiting for update.)
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:86)
10777  |  ARPP21  |  DISEASES
4282  |  MIF  |  DISEASES
4350  |  MPG  |  DISEASES
973  |  CD79A  |  DISEASES
10392  |  NOD1  |  DISEASES
55131  |  RBM28  |  DISEASES
4353  |  MPO  |  DISEASES
3558  |  IL2  |  DISEASES
4057  |  LTF  |  DISEASES
9173  |  IL1RL1  |  DISEASES
566  |  AZU1  |  DISEASES
64895  |  PAPOLG  |  DISEASES
54210  |  TREM1  |  DISEASES
9459  |  ARHGEF6  |  DISEASES
10343  |  PKDREJ  |  DISEASES
2161  |  F12  |  DISEASES
1401  |  CRP  |  DISEASES
1131  |  CHRM3  |  DISEASES
3569  |  IL6  |  DISEASES
3658  |  IREB2  |  DISEASES
4223  |  MEOX2  |  DISEASES
23523  |  CABIN1  |  DISEASES
3552  |  IL1A  |  DISEASES
3553  |  IL1B  |  DISEASES
10140  |  TOB1  |  DISEASES
54858  |  PGPEP1  |  DISEASES
3934  |  LCN2  |  DISEASES
133  |  ADM  |  DISEASES
5281  |  PIGF  |  DISEASES
5205  |  ATP8B1  |  DISEASES
6352  |  CCL5  |  DISEASES
3577  |  CXCR1  |  DISEASES
213  |  ALB  |  DISEASES
2921  |  CXCL3  |  DISEASES
6374  |  CXCL5  |  DISEASES
134288  |  TMEM174  |  DISEASES
360  |  AQP3  |  DISEASES
6340  |  SCNN1G  |  DISEASES
4589  |  MUC7  |  DISEASES
4330  |  MN1  |  DISEASES
3627  |  CXCL10  |  DISEASES
7369  |  UMOD  |  DISEASES
3661  |  IRF3  |  DISEASES
64755  |  C16orf58  |  DISEASES
3579  |  CXCR2  |  DISEASES
2  |  A2M  |  DISEASES
7100  |  TLR5  |  DISEASES
26762  |  HAVCR1  |  DISEASES
84706  |  GPT2  |  DISEASES
273  |  AMPH  |  DISEASES
871  |  SERPINH1  |  DISEASES
51150  |  SDF4  |  DISEASES
26580  |  BSCL2  |  DISEASES
8532  |  CPZ  |  DISEASES
10724  |  MGEA5  |  DISEASES
4283  |  CXCL9  |  DISEASES
5406  |  PNLIP  |  DISEASES
1369  |  CPN1  |  DISEASES
959  |  CD40LG  |  DISEASES
2022  |  ENG  |  DISEASES
10800  |  CYSLTR1  |  DISEASES
7099  |  TLR4  |  DISEASES
51230  |  PHF20  |  DISEASES
8874  |  ARHGEF7  |  DISEASES
353116  |  RILPL1  |  DISEASES
5100  |  PCDH8  |  DISEASES
4868  |  NPHS1  |  DISEASES
3030  |  HADHA  |  DISEASES
55858  |  TMEM165  |  DISEASES
11082  |  ESM1  |  DISEASES
10333  |  TLR6  |  DISEASES
9467  |  SH3BP5  |  DISEASES
22900  |  CARD8  |  DISEASES
2919  |  CXCL1  |  DISEASES
3652  |  IPP  |  DISEASES
1438  |  CSF2RA  |  DISEASES
7124  |  TNF  |  DISEASES
84148  |  KAT8  |  DISEASES
23098  |  SARM1  |  DISEASES
3586  |  IL10  |  DISEASES
4700  |  NDUFA6  |  DISEASES
2920  |  CXCL2  |  DISEASES
51271  |  UBAP1  |  DISEASES
5228  |  PGF  |  DISEASES
567  |  B2M  |  DISEASES
677807  |  SNORA22  |  DISEASES
Locus(Waiting for update.)
Disease ID 1763
Disease acute pyelonephritis
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:18)
HP:0100699  |  Scarring  |  7
HP:0001919  |  Acute renal failure  |  5
HP:0000010  |  Frequent urinary tract infections  |  3
HP:0100806  |  Sepsis  |  3
HP:0000819  |  Diabetes mellitus  |  2
HP:0000083  |  Renal insufficiency  |  1
HP:0030731  |  Carcinoma  |  1
HP:0001397  |  Hepatic steatosis  |  1
HP:0001903  |  Anemia  |  1
HP:0011779  |  Anaplastic thyroid carcinoma  |  1
HP:0001945  |  Fever  |  1
HP:0000121  |  Nephrocalcinosis  |  1
HP:0000138  |  Ovarian cyst  |  1
HP:0012461  |  Bacteria in urine  |  1
HP:0006573  |  Acute fatty liver  |  1
HP:0002890  |  Thyroid carcinoma  |  1
HP:0000076  |  Vesicoureteric reflux  |  1
HP:0000126  |  Hydronephrosis  |  1
Disease ID 1763
Disease acute pyelonephritis
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:5)
C0004610  |  bacteremia  |  6
C0036690  |  sepsis  |  3
C1096262  |  escherichia coli bacteremia  |  1
C0015967  |  fever  |  1
C0022660  |  acute renal failure  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:2)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs3804099234840497097TLR2umls:C0520575BeFreeFurther genotype pattern frequency analysis in TLR-2 SNPs (rs3804099 and rs3804100) showed significantly reduced occurrence of the rare allele homozygote (CC+CC) in the no-VUR subgroup of APN and ALN cases.0.0002714422013TLR24153703504TC
rs3804100234840497097TLR2umls:C0520575BeFreeFurther genotype pattern frequency analysis in TLR-2 SNPs (rs3804099 and rs3804100) showed significantly reduced occurrence of the rare allele homozygote (CC+CC) in the no-VUR subgroup of APN and ALN cases.0.0002714422013TLR24153704257TC
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:0)
(Waiting for update.)
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)