All Snps(Total Genotypes:44) |
|---|
| snpId |
pubmedId |
geneId |
geneSymbol |
diseaseId |
sourceId |
sentence |
score |
Year |
geneSymbol_dbSNP |
CHROMOSOME |
POS |
REF |
ALT |
| rs1064039 | 15882666 | 1471 | CST3 | umls:C0155626 | BeFree | Cystatin C levels are decreased in acute myocardial infarction: effect of cystatin C G73A gene polymorphism on plasma levels. | 0.000271442 | 2005 | CST3 | 20 | 23637790 | C | T |
| rs121917864 | 18442320 | 7097 | TLR2 | umls:C0155626 | BeFree | TLR2 and age-related diseases: potential effects of Arg753Gln and Arg677Trp polymorphisms in acute myocardial infarction. | 0.000542884 | 2008 | TLR2 | 4 | 153704936 | C | T |
| rs12375498 | 24667032 | 5069 | PAPPA | umls:C0155626 | BeFree | Cys327Cys PAPP-A polymorphism (SNP) (rs12375498) was found to be of significance in preeclampsia and the C allele of the PAPP-A C/G SNP (rs13290387) was defined as an independent risk factor for acute myocardial infarction. | 0.000814326 | 2014 | PAPPA | 9 | 116187719 | C | T |
| rs13290387 | 24667032 | 5069 | PAPPA | umls:C0155626 | BeFree | Cys327Cys PAPP-A polymorphism (SNP) (rs12375498) was found to be of significance in preeclampsia and the C allele of the PAPP-A C/G SNP (rs13290387) was defined as an independent risk factor for acute myocardial infarction. | 0.000814326 | 2014 | PAPPA | 9 | 116227647 | G | C |
| rs1799983 | 15284679 | 4846 | NOS3 | umls:C0155626 | BeFree | Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results are insufficient and contradictory, such as those about the association between the polymorphism G894T in the eNOS gene or the polymorphism C677T in the MTHFR gene and young AMI. | 0.002714419 | 2004 | NOS3 | 7 | 150999023 | T | G |
| rs1799983 | 15284679 | 4524 | MTHFR | umls:C0155626 | BeFree | Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results are insufficient and contradictory, such as those about the association between the polymorphism G894T in the eNOS gene or the polymorphism C677T in the MTHFR gene and young AMI. | 0.002714419 | 2004 | NOS3 | 7 | 150999023 | T | G |
| rs1799983 | 12243851 | 4846 | NOS3 | umls:C0155626 | BeFree | Recent reports have suggested that the Glu298Asp polymorphism in exon 7 of the endothelial nitric oxide synthase gene is associated with coronary spasm and acute myocardial infarction. | 0.002714419 | 2002 | NOS3 | 7 | 150999023 | T | G |
| rs1799983 | 15284679 | 5972 | REN | umls:C0155626 | BeFree | Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results are insufficient and contradictory, such as those about the association between the polymorphism G894T in the eNOS gene or the polymorphism C677T in the MTHFR gene and young AMI. | 0.001628651 | 2004 | NOS3 | 7 | 150999023 | T | G |
| rs1801253 | 12851615 | 153 | ADRB1 | umls:C0155626 | BeFree | Our findings suggest that the genotype of Arg389Gly polymorphism in the human ADRB1 gene is associated with AMI. | 0.000542884 | 2003 | ADRB1 | 10 | 114045297 | G | C |
| rs1801282 | 18561518 | 5468 | PPARG | umls:C0155626 | BeFree | The alanine allele of P12A polymorphism in PPARG gene in a few studies has been associated with a reduced or increased risk of acute myocardial infarction (AMI). | 0.000542884 | 2008 | PPARG | 3 | 12351626 | C | G |
| rs1805017 | 24732951 | 7941 | PLA2G7 | umls:C0155626 | BeFree | In high-risk coronary artery disease patients of European ancestry, the PLA2G7 rs1805017 GG genotype is associated with increased Lp-PLA2 plasma activity and AMI. | 0.000271442 | 2015 | PLA2G7 | 6 | 46716485 | C | T |
| rs1805123 | 22338672 | 3757 | KCNH2 | umls:C0155626 | BeFree | Thus, patients with an acute MI carrying the KCNH2-K897T polymorphism had an 8-fold greater risk of experiencing TdP compared with controls (95% confidence interval = 2-40). | 0.000271442 | 2012 | KCNH2 | 7 | 150948446 | T | G,A |
| rs1805192 | 18561518 | 5468 | PPARG | umls:C0155626 | BeFree | The alanine allele of P12A polymorphism in PPARG gene in a few studies has been associated with a reduced or increased risk of acute myocardial infarction (AMI). | 0.000542884 | 2008 | PPARG | 3 | 12379739 | C | G |
| rs199473244 | 24445991 | 6331 | SCN5A | umls:C0155626 | BeFree | We report identification and functional characterization of a rare non-synonymous (p.A1427S) variant in the SCN5A gene that was associated with incessant and lethal ventricular tachycardia and fibrillation after administration of lidocaine to a patient with acute myocardial infarction. | 0.001357209 | 2013 | SCN5A | 3 | 38557251 | C | A |
| rs200034939 | 24445991 | 6331 | SCN5A | umls:C0155626 | BeFree | We report identification and functional characterization of a rare non-synonymous (p.A1427S) variant in the SCN5A gene that was associated with incessant and lethal ventricular tachycardia and fibrillation after administration of lidocaine to a patient with acute myocardial infarction. | 0.001357209 | 2013 | SCN5A | 3 | 38557248 | C | A |
| rs200478651 | 12486862 | 2155 | F7 | umls:C0155626 | BeFree | Associations of the known polymorphisms of the coagulation factor VII (FVII) gene (R353Q), the coagulation factor XIII (FXIII) gene (V34L) and the glycoprotein Ia (Gp1a) gene (C807T) with the occurrence of AMI were studied in 142 AMI survivors and 142 age- and sex-matched control subjects. | 0.001357209 | 2002 | F7 | 13 | 113118414 | C | A,T |
| rs200478651 | 12486862 | 22915 | MMRN1 | umls:C0155626 | BeFree | Associations of the known polymorphisms of the coagulation factor VII (FVII) gene (R353Q), the coagulation factor XIII (FXIII) gene (V34L) and the glycoprotein Ia (Gp1a) gene (C807T) with the occurrence of AMI were studied in 142 AMI survivors and 142 age- and sex-matched control subjects. | 0.000814326 | 2002 | F7 | 13 | 113118414 | C | A,T |
| rs201058276 | 11578716 | 2155 | F7 | umls:C0155626 | BeFree | In order to determine the role of two polymorphisms in the factor VII gene (R353Q and intron 7 hypervariable region) in the susceptibility to develop early myocardial infarction, a total of 175 patients with acute myocardial infarction aged 50 years or less (mean age 41+/-7 years) and 200 controls (average age 42+/-6) without cardiovascular disease were genotyped for these polymorphisms. | 0.001357209 | 2001 | F7 | 13 | 113118731 | G | A |
| rs201058276 | 12486862 | 22915 | MMRN1 | umls:C0155626 | BeFree | Associations of the known polymorphisms of the coagulation factor VII (FVII) gene (R353Q), the coagulation factor XIII (FXIII) gene (V34L) and the glycoprotein Ia (Gp1a) gene (C807T) with the occurrence of AMI were studied in 142 AMI survivors and 142 age- and sex-matched control subjects. | 0.000814326 | 2002 | F7 | 13 | 113118731 | G | A |
| rs201058276 | 12486862 | 2155 | F7 | umls:C0155626 | BeFree | Associations of the known polymorphisms of the coagulation factor VII (FVII) gene (R353Q), the coagulation factor XIII (FXIII) gene (V34L) and the glycoprotein Ia (Gp1a) gene (C807T) with the occurrence of AMI were studied in 142 AMI survivors and 142 age- and sex-matched control subjects. | 0.001357209 | 2002 | F7 | 13 | 113118731 | G | A |
| rs2069709 | 18056971 | 3586 | IL10 | umls:C0155626 | BeFree | We identified four genetic risk sets for acute myocardial infarction (AMI) from information on functional gene variants that favor inflammation or modulate cholesterol metabolism: IL6 -174 G/C, TNF -308 G/A, IL10 -1082 G/A, SERPINA3 -51 G/T, IFNG +874 T/A, HMGCR -911 C/A, and APOE epsilon2/3/4; 316 patients and 461 healthy subjects, all Italian. | 0.001085767 | 2007 | IFNG | 12 | 68159923 | C | A |
| rs2069709 | 18056971 | 12 | SERPINA3 | umls:C0155626 | BeFree | We identified four genetic risk sets for acute myocardial infarction (AMI) from information on functional gene variants that favor inflammation or modulate cholesterol metabolism: IL6 -174 G/C, TNF -308 G/A, IL10 -1082 G/A, SERPINA3 -51 G/T, IFNG +874 T/A, HMGCR -911 C/A, and APOE epsilon2/3/4; 316 patients and 461 healthy subjects, all Italian. | 0.000271442 | 2007 | IFNG | 12 | 68159923 | C | A |
| rs2069709 | 18056971 | 3156 | HMGCR | umls:C0155626 | BeFree | We identified four genetic risk sets for acute myocardial infarction (AMI) from information on functional gene variants that favor inflammation or modulate cholesterol metabolism: IL6 -174 G/C, TNF -308 G/A, IL10 -1082 G/A, SERPINA3 -51 G/T, IFNG +874 T/A, HMGCR -911 C/A, and APOE epsilon2/3/4; 316 patients and 461 healthy subjects, all Italian. | 0.000814326 | 2007 | IFNG | 12 | 68159923 | C | A |
| rs2069709 | 18056971 | 7124 | TNF | umls:C0155626 | BeFree | We identified four genetic risk sets for acute myocardial infarction (AMI) from information on functional gene variants that favor inflammation or modulate cholesterol metabolism: IL6 -174 G/C, TNF -308 G/A, IL10 -1082 G/A, SERPINA3 -51 G/T, IFNG +874 T/A, HMGCR -911 C/A, and APOE epsilon2/3/4; 316 patients and 461 healthy subjects, all Italian. | 0.00434307 | 2007 | IFNG | 12 | 68159923 | C | A |
| rs2069709 | 18056971 | 348 | APOE | umls:C0155626 | BeFree | We identified four genetic risk sets for acute myocardial infarction (AMI) from information on functional gene variants that favor inflammation or modulate cholesterol metabolism: IL6 -174 G/C, TNF -308 G/A, IL10 -1082 G/A, SERPINA3 -51 G/T, IFNG +874 T/A, HMGCR -911 C/A, and APOE epsilon2/3/4; 316 patients and 461 healthy subjects, all Italian. | 0.001085767 | 2007 | IFNG | 12 | 68159923 | C | A |
| rs2069709 | 18056971 | 3458 | IFNG | umls:C0155626 | BeFree | We identified four genetic risk sets for acute myocardial infarction (AMI) from information on functional gene variants that favor inflammation or modulate cholesterol metabolism: IL6 -174 G/C, TNF -308 G/A, IL10 -1082 G/A, SERPINA3 -51 G/T, IFNG +874 T/A, HMGCR -911 C/A, and APOE epsilon2/3/4; 316 patients and 461 healthy subjects, all Italian. | 0.000542884 | 2007 | IFNG | 12 | 68159923 | C | A |
| rs2227721 | 23041018 | 790 | CAD | umls:C0155626 | BeFree | The rs2227721 was associated with susceptibility of vascular disease; the odds ratios among subjects carrying rs2227721-T allele were 1.298 (95% Confidence Interval-CI, 1.033-1.631) for non-MI CAD (P<0.05), 1.346 (95% CI, 1.068-1.695) for chronic MI (P<0.05), 1.486 (95% CI, 1.145-1.928) for acute MI (P<0.001), and 1.619 (95% CI, 1.108-2.366) for deep venous thrombosis (P<0.05). | 0.001357209 | 2012 | VTN;SARM1 | 17 | 28370430 | C | A |
| rs34637584 | 16966501 | 120892 | LRRK2 | umls:C0155626 | BeFree | Five LRRK2 G2019S carriers were identified, of whom 4 had Parkinson disease (clinically and pathologically confirmed), and the fifth was a control subject who died at age 68 years after an acute myocardial infarction with no evidence of neurodegenerative abnormalities. | 0.000271442 | 2006 | LRRK2 | 12 | 40340400 | G | A |
| rs375752214 | 15284679 | 4524 | MTHFR | umls:C0155626 | BeFree | Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results are insufficient and contradictory, such as those about the association between the polymorphism G894T in the eNOS gene or the polymorphism C677T in the MTHFR gene and young AMI. | 0.002714419 | 2004 | NOS3 | 7 | 150998541 | C | T |
| rs375752214 | 15284679 | 5972 | REN | umls:C0155626 | BeFree | Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results are insufficient and contradictory, such as those about the association between the polymorphism G894T in the eNOS gene or the polymorphism C677T in the MTHFR gene and young AMI. | 0.001628651 | 2004 | NOS3 | 7 | 150998541 | C | T |
| rs375752214 | 15284679 | 4846 | NOS3 | umls:C0155626 | BeFree | Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results are insufficient and contradictory, such as those about the association between the polymorphism G894T in the eNOS gene or the polymorphism C677T in the MTHFR gene and young AMI. | 0.002714419 | 2004 | NOS3 | 7 | 150998541 | C | T |
| rs386602276 | 10781645 | 3356 | HTR2A | umls:C0155626 | BeFree | T102C polymorphism of the serotonin (5-HT) 2A receptor gene in patients with non-fatal acute myocardial infarction. | 0.001085767 | 2000 | NA | NA | NA | NA | NA |
| rs386602276 | 17713649 | 3356 | HTR2A | umls:C0155626 | BeFree | T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism. | 0.001085767 | 2007 | NA | NA | NA | NA | NA |
| rs397507444 | 17412321 | 4524 | MTHFR | umls:C0155626 | BeFree | We have examined the prevalence of the C677T and A1298C single nucleotide polymorphisms (SNPs) in the methylenetetrahydrofolate reductase (MTHFR) gene in healthy Tamilians and in patients with acute myocardial infarction and related this polymorphism to plasma homocysteine concentrations, serum folate, serum cobalamin and riboflavin status. | 0.002714419 | 2007 | MTHFR | 1 | 11794407 | T | G |
| rs4986790 | 17587646 | 7099 | TLR4 | umls:C0155626 | BeFree | Recently, the common Asp299Gly polymorphism of the Toll-like receptor 4 (TLR-4) was found to be associated with a reduced incidence of acute myocardial infarction and carotid atherosclerosis. | 0.002171535 | 2007 | TLR4 | 9 | 117713024 | A | G |
| rs5743708 | 18442320 | 7097 | TLR2 | umls:C0155626 | BeFree | TLR2 and age-related diseases: potential effects of Arg753Gln and Arg677Trp polymorphisms in acute myocardial infarction. | 0.000542884 | 2008 | TLR2 | 4 | 153705165 | G | A |
| rs6313 | 10781645 | 3356 | HTR2A | umls:C0155626 | BeFree | T102C polymorphism of the serotonin (5-HT) 2A receptor gene in patients with non-fatal acute myocardial infarction. | 0.001085767 | 2000 | HTR2A | 13 | 46895805 | G | A |
| rs6313 | 17713649 | 3356 | HTR2A | umls:C0155626 | BeFree | T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism. | 0.001085767 | 2007 | HTR2A | 13 | 46895805 | G | A |
| rs662799 | 26731984 | 116519 | APOA5 | umls:C0155626 | BeFree | Only two SNPs, rs662799 (APOA5) and rs964184 (ZNF259) found at two independent loci, were associated with risk of MI in the Chinese Han population. | 0.000542884 | 2016 | APOA5 | 11 | 116792991 | G | A |
| rs662799 | 26731984 | 8882 | ZPR1 | umls:C0155626 | BeFree | Only two SNPs, rs662799 (APOA5) and rs964184 (ZNF259) found at two independent loci, were associated with risk of MI in the Chinese Han population. | 0.000271442 | 2016 | APOA5 | 11 | 116792991 | G | A |
| rs7493 | 19540141 | 5445 | PON2 | umls:C0155626 | BeFree | We analyzed the PON2 C311S polymorphism in 442 elderly patients who had experienced an AMI. | 0.000271442 | 2009 | PON2 | 7 | 95405463 | G | C |
| rs8193037 | 21062626 | 3605 | IL17A | umls:C0155626 | BeFree | Based on our data, we speculated that the SNP rs8193037 of IL17A gene is significantly associated with CAD risk in Chinese Han population and the rs8193037 G allele which is associated with increased expression of IL17A in AMI patients may be an independent predictive factor for CAD. | 0.000542884 | 2011 | IL17A | 6 | 52186311 | G | A |
| rs964184 | 26731984 | 8882 | ZPR1 | umls:C0155626 | BeFree | Only two SNPs, rs662799 (APOA5) and rs964184 (ZNF259) found at two independent loci, were associated with risk of MI in the Chinese Han population. | 0.000271442 | 2016 | ZPR1 | 11 | 116778201 | G | C |
| rs964184 | 26731984 | 116519 | APOA5 | umls:C0155626 | BeFree | Only two SNPs, rs662799 (APOA5) and rs964184 (ZNF259) found at two independent loci, were associated with risk of MI in the Chinese Han population. | 0.000542884 | 2016 | ZPR1 | 11 | 116778201 | G | C |
