PedAM

Pediatric Disease Annotations & Medicines


	acute monocytic leukemia

Disease ID	829
Disease	acute monocytic leukemia
Definition	An acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage including monoblasts, promonocytes, and MONOCYTES.
Synonym	[m]acute monocytic leukaemia [m]acute monocytic leukaemia (disorder) [m]acute monocytic leukemia acute monoblastic leukaemia acute monoblastic leukemia acute monoblastic leukemias acute monocytic leukaemia acute monocytic leukaemia, fab m5 acute monocytic leukemia, fab m5 acute monocytic leukemia, fab m5 (disorder) acute monocytic leukemia, morphology acute monocytic leukemia, morphology (morphologic abnormality) acute monocytic leukemias disorder: acute monocytic leukemia, fab m5 (disorder) fab m5 leukemia monoblastic acute leukemia myeloid acute m 05 leukemia, acute monocytic leukemia, monoblastic, acute leukemia, monocytic, acute leukemia, monocytic, acute [disease/finding] leukemia, myeloid, acute, m5 leukemia, myeloid, schilling type leukemia, myeloid, schilling-type leukemia, schilling-type myeloid leukemias, acute monoblastic leukemias, acute monocytic monoblastic leukemia, acute monoblastic leukemias, acute monocytic leukemia, acute monocytic leukemias, acute myeloid leukemia acute m 05 myeloid leukemia, acute, m5 myeloid leukemia, schilling type myeloid leukemia, schilling-type schilling-type myeloid leukemia
Orphanet	ORPHANET:514
OMIM	OMIM:151380
DOID	DOID:8864
UMLS	C0023465
MeSH	D007948
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:10) C0024314 \| lymphoproliferative disorder \| 1 C0024291 \| hemophagocytic syndrome \| 1 C0024314 \| lymphoproliferative disorders \| 1 C1261473 \| sarcoma \| 1 C0023434 \| chronic lymphocytic leukemia \| 1 C0002871 \| anemia \| 1 C0023448 \| lymphocytic leukemia \| 1 C0002874 \| aplastic anemia \| 1 C0023418 \| leukemia \| 1 C0013080 \| trisomy 21 \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) DNMT3A \| 1788 \| CTD_human KMT2A \| 4297 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:176) 9703 \| KIAA0100 \| DISEASES 6376 \| CX3CL1 \| DISEASES 928 \| CD9 \| DISEASES 4830 \| NME1 \| DISEASES 350 \| APOH \| DISEASES 7049 \| TGFBR3 \| DISEASES 6367 \| CCL22 \| DISEASES 56915 \| EXOSC5 \| DISEASES 4353 \| MPO \| DISEASES 6347 \| CCL2 \| DISEASES 952 \| CD38 \| DISEASES 595 \| CCND1 \| DISEASES 3458 \| IFNG \| DISEASES 5273 \| SERPINB10 \| DISEASES 2322 \| FLT3 \| DISEASES 3759 \| KCNJ2 \| DISEASES 8744 \| TNFSF9 \| DISEASES 83596 \| BCL2L12 \| DISEASES 391013 \| PLA2G2C \| DISEASES 968 \| CD68 \| DISEASES 4695 \| NDUFA2 \| DISEASES 3741 \| KCNA5 \| DISEASES 4298 \| MLLT1 \| DISEASES 5914 \| RARA \| DISEASES 3569 \| IL6 \| DISEASES 7097 \| TLR2 \| DISEASES 25833 \| POU2F3 \| DISEASES 10113 \| PREB \| DISEASES 4069 \| LYZ \| DISEASES 5687 \| PSMA6 \| DISEASES 81617 \| CAB39L \| DISEASES 1975 \| EIF4B \| DISEASES 4481 \| MSR1 \| DISEASES 945 \| CD33 \| DISEASES 1387 \| CREBBP \| DISEASES 8178 \| ELL \| DISEASES 29904 \| EEF2K \| DISEASES 8424 \| BBOX1 \| DISEASES 2033 \| EP300 \| DISEASES 5024 \| P2RX3 \| DISEASES 3553 \| IL1B \| DISEASES 2817 \| GPC1 \| DISEASES 1788 \| DNMT3A \| DISEASES 3383 \| ICAM1 \| DISEASES 259 \| AMBP \| DISEASES 7994 \| KAT6A \| DISEASES 3687 \| ITGAX \| DISEASES 6455 \| SH3GL1 \| DISEASES 91937 \| TIMD4 \| DISEASES 23196 \| FAM120A \| DISEASES 3606 \| IL18 \| DISEASES 291 \| SLC25A4 \| DISEASES 64422 \| ATG3 \| DISEASES 5468 \| PPARG \| DISEASES 3815 \| KIT \| DISEASES 50848 \| F11R \| DISEASES 267 \| AMFR \| DISEASES 51517 \| NCKIPSD \| DISEASES 7412 \| VCAM1 \| DISEASES 50852 \| TRAT1 \| DISEASES 3148 \| HMGB2 \| DISEASES 308 \| ANXA5 \| DISEASES 27343 \| POLL \| DISEASES 290 \| ANPEP \| DISEASES 10653 \| SPINT2 \| DISEASES 7083 \| TK1 \| DISEASES 64581 \| CLEC7A \| DISEASES 929 \| CD14 \| DISEASES 29071 \| C1GALT1C1 \| DISEASES 8028 \| MLLT10 \| DISEASES 4323 \| MMP14 \| DISEASES 4973 \| OLR1 \| DISEASES 5653 \| KLK6 \| DISEASES 48 \| ACO1 \| DISEASES 1072 \| CFL1 \| DISEASES 947 \| CD34 \| DISEASES 5029 \| P2RY2 \| DISEASES 836 \| CASP3 \| DISEASES 79870 \| BAALC \| DISEASES 80169 \| CTC1 \| DISEASES 1662 \| DDX10 \| DISEASES 4928 \| NUP98 \| DISEASES 4302 \| MLLT6 \| DISEASES 375757 \| SWI5 \| DISEASES 4684 \| NCAM1 \| DISEASES 51157 \| ZNF580 \| DISEASES 9322 \| TRIP10 \| DISEASES 4018 \| LPA \| DISEASES 1153 \| CIRBP \| DISEASES 5032 \| P2RY11 \| DISEASES 146722 \| CD300LF \| DISEASES 1435 \| CSF1 \| DISEASES 3563 \| IL3RA \| DISEASES 1789 \| DNMT3B \| DISEASES 84295 \| PHF6 \| DISEASES 9146 \| HGS \| DISEASES 6401 \| SELE \| DISEASES 942 \| CD86 \| DISEASES 8338 \| HIST2H2AC \| DISEASES 10227 \| MFSD10 \| DISEASES 1233 \| CCR4 \| DISEASES 2152 \| F3 \| DISEASES 3984 \| LIMK1 \| DISEASES 114548 \| NLRP3 \| DISEASES 5269 \| SERPINB6 \| DISEASES 4602 \| MYB \| DISEASES 3720 \| JARID2 \| DISEASES 3146 \| HMGB1 \| DISEASES 5348 \| FXYD1 \| DISEASES 22953 \| P2RX2 \| DISEASES 3205 \| HOXA9 \| DISEASES 4542 \| MYO1F \| DISEASES 6144 \| RPL21 \| DISEASES 2331 \| FMOD \| DISEASES 130013 \| ACMSD \| DISEASES 5625 \| PRODH \| DISEASES 10987 \| COPS5 \| DISEASES 2526 \| FUT4 \| DISEASES 9332 \| CD163 \| DISEASES 10137 \| RBM12 \| DISEASES 3201 \| HOXA4 \| DISEASES 7037 \| TFRC \| DISEASES 5599 \| MAPK8 \| DISEASES 2882 \| GPX7 \| DISEASES 9619 \| ABCG1 \| DISEASES 961 \| CD47 \| DISEASES 5788 \| PTPRC \| DISEASES 962 \| CD48 \| DISEASES 6280 \| S100A9 \| DISEASES 4942 \| OAT \| DISEASES 5710 \| PSMD4 \| DISEASES 8337 \| HIST2H2AA3 \| DISEASES 2209 \| FCGR1A \| DISEASES 914 \| CD2 \| DISEASES 3738 \| KCNA3 \| DISEASES 4774 \| NFIA \| DISEASES 3725 \| JUN \| DISEASES 2060 \| EPS15 \| DISEASES 958 \| CD40 \| DISEASES 4318 \| MMP9 \| DISEASES 7075 \| TIE1 \| DISEASES 8565 \| YARS \| DISEASES 7099 \| TLR4 \| DISEASES 5030 \| P2RY4 \| DISEASES 19 \| ABCA1 \| DISEASES 10006 \| ABI1 \| DISEASES 3105 \| HLA-A \| DISEASES 7161 \| TP73 \| DISEASES 54790 \| TET2 \| DISEASES 4300 \| MLLT3 \| DISEASES 6370 \| CCL25 \| DISEASES 2113 \| ETS1 \| DISEASES 654364 \| NME1-NME2 \| DISEASES 4831 \| NME2 \| DISEASES 8301 \| PICALM \| DISEASES 153218 \| SPINK13 \| DISEASES 84444 \| DOT1L \| DISEASES 8115 \| TCL1A \| DISEASES 23210 \| JMJD6 \| DISEASES 960 \| CD44 \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 10499 \| NCOA2 \| DISEASES 5795 \| PTPRJ \| DISEASES 2821 \| GPI \| DISEASES 51652 \| CHMP3 \| DISEASES 79897 \| RPP21 \| DISEASES 834 \| CASP1 \| DISEASES 10043 \| TOM1 \| DISEASES 6256 \| RXRA \| DISEASES 930 \| CD19 \| DISEASES 3684 \| ITGAM \| DISEASES 9141 \| PDCD5 \| DISEASES 645030 \| NFIA-AS1 \| DISEASES 677833 \| SNORA54 \| DISEASES 285194 \| TUSC7 \| DISEASES
Locus	(Waiting for update.)

Disease ID	829
Disease	acute monocytic leukemia
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:1) HP:0004845 \| Acute monoblastic leukemia
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:9) HP:0001903 \| Anemia \| 1 HP:0001909 \| Leukemia \| 1 HP:0001915 \| Aplastic anemia \| 1 HP:0005523 \| Lymphoproliferative disorder \| 1 HP:0001945 \| Fever \| 1 HP:0100523 \| Hepatic abscess \| 1 HP:0100242 \| Sarcoma \| 1 HP:0005550 \| Chronic lymphatic leukemia \| 1 HP:0002170 \| Intracranial hemorrhage \| 1

Disease ID	829
Disease	acute monocytic leukemia
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0948976 \| leukemia cutis \| 1 C0023885 \| liver abscesses \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0023465	arsenic trioxide	C006632	1327-53-3	leukemia, monocytic, acute	MESH:D007948	therapeutic	16972261

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

Web
Analytics