PedAM
Pediatric Disease Annotations & Medicines
| acute hemorrhagic leukoencephalitis | ||||
| Disease ID | 995 |
|---|---|
| Disease | acute hemorrhagic leukoencephalitis |
| Definition | A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5) |
| Synonym | acute haemorrhagic leucoencephalitis acute haemorrhagic leucoencephalitis of weston hurst acute hemorrhagic encephalomyelitides acute hemorrhagic encephalomyelitis acute hemorrhagic leukoencephalitides acute hemorrhagic leukoencephalitis (disorder) acute hemorrhagic leukoencephalitis of weston hurst ahl disease, hurst disease, hurst's enceph acute necrotizing hemorrhagic encephalomyelitides, acute hemorrhagic encephalomyelitis, acute hemorrhagic encephalomyelitis, acute necrotizing hemorrhagic encephalomyelitis, necrotizing hemorrhagic, acute hemorrhagic encephalomyelitides, acute hemorrhagic encephalomyelitis, acute hemorrhagic leukoencephalitides, acute hemorrhagic leukoencephalitis, acute hurst dis hurst disease hurst syndrome hurst's disease hursts dis hursts disease leukoenceph acute hemorrhagic leukoencephalitides, acute hemorrhagic leukoencephalitis acuta hemorrhagica leukoencephalitis, acute hemorrhagic leukoencephalitis, acute hemorrhagic [disease/finding] leukoencephalitis, hemorrhagic, acute syndrome, hurst |
| OMIM | |
| DOID | |
| UMLS | C0014077 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:4) C0009319 | colitis | 1 C0026848 | myopathy | 1 C0009324 | ulcerative colitis | 1 C0026769 | multiple sclerosis | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:13) |
| Locus | (Waiting for update.) |
| Disease ID | 995 |
|---|---|
| Disease | acute hemorrhagic leukoencephalitis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:3) |
| Disease ID | 995 |
|---|---|
| Disease | acute hemorrhagic leukoencephalitis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0014077 | pyrimethamine | D011739 | 58-14-0 | leukoencephalitis, acute hemorrhagic | MESH:D004684 | therapeutic | 17907889 | ||
| C0014077 | sulfadiazine | D013411 | 68-35-9 | leukoencephalitis, acute hemorrhagic | MESH:D004684 | therapeutic | 17907889 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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